ライフサイエンスコーパス: haematobium

1 um that are coinfected with S. mansoni or S. haematobium.

2 red with Schistosoma mansoni and Schistosoma haematobium.

3 parasitic trematode blood fluke Schistosoma haematobium.

4 ure of acetylcholinesterase from Schistosoma haematobium.

5 h endemic Schistosoma mansoni or Schistosoma haematobium.

6 h either Wuchereria bancrofti or Schistosoma haematobium.

7 scontinuity between northern and southern S. haematobium.

8 Urine examination revealed eggs of S. haematobium.

9 ew advances that will deepen knowledge of S. haematobium.

10 nown to exhibit activity against Schistosoma haematobium.

11 educes morbidity is proposed for Schistosoma haematobium, a parasite of major public health importanc

12 Schistosoma haematobium, a parasitic flatworm that infects more than

13 species and cloned the complete gene for S. haematobium AChE.

14 nd 96% NPV, and a boosted trees model for S. haematobium achieves 77% sensitivity, 95% specificity, a

15 nce), and a regression model for Schistosoma haematobium achieves 90% sensitivity, 90% specificity, a

16 tterns of recognition of defined Schistosoma haematobium adult worm antigens by serum antibodies from

17 aused by the parasitic trematode Schistosoma haematobium, affects over 112 million people worldwide.

18 indicate a diversity of lesions caused by S. haematobium and a dynamic evolution of the genital lesio

19 ted with Schistosoma mansoni and Schistosoma haematobium and considers the practical implications of

20 erative to search for new drug targets in S. haematobium and other schistosomes.

21 -1 gene (Mta1) product in the survival of S. haematobium and productive infection in the host.

22 ecimens to determine the seroprevalence of S haematobium and S mansoni by ELISA and immunoblot analys

23 ty and specificity of diagnostic tests for S haematobium and S mansoni infections against Kato-Katz t

24 The arithmetic mean egg intensities for S. haematobium and S. mansoni were 18.5 mean eggs/10 ml (95

25 n rural Tanzania with high prevalences of S. haematobium and S. mansoni, respectively.

26 s reference diagnostic tests for Schistosoma haematobium and Schistosoma mansoni infections, respecti

27 The literature search identified Schistosoma haematobium and Schistosoma mansoni surveys done in, res

28 992 validated and predicted proteins from S haematobium and screened it with serum and urine antibod

29 vides a global insight into the kinome of S. haematobium and should assist the repurposing or discove

30 the AChE from the human parasite Schistosoma haematobium and succeeded in expressing functional recom

31 Hybridisation between S haematobium and the cattle schistosome S bovis had a put

32 ution of Schistosoma mansoni and Schistosoma haematobium and the incidence of schistosomiasis in area

33 water exposure was limited to Lake Malawi; S haematobium antibodies were found in 135 of 141 (96%) se

34 he most comprehensive characterization of S. haematobium antigens to date and describes novel antigen

35 verrini, Clonorchis sinensis and Schistosoma haematobium are classified as Group 1 biological carcino

36 errini, Clonorchis sinensis, and Schistosoma haematobium are classified as group 1 biological carcino

37 ons, we also show that where S. bovis and S. haematobium are coendemic (in livestock and humans respe

38 Most kinases of S. haematobium are very similar to those of its congener, S

39 ts, Schistosoma japonicum, S. mansoni and S. haematobium, are blood flukes that have complex life cyc

40 h on Cancer classifies the infection with S. haematobium as a group 1 carcinogen, a definitive cause

41 To study the mechanisms of S. haematobium-bacterial urinary tract coinfections, we com

42 the genome for a key intermediate host of S. haematobium-called Bulinus truncatus-and explore protein

43 The blood fluke Schistosoma haematobium causes urogenital schistosomiasis, a neglect

44 rvention for reducing the transmission of S. haematobium [corrected] is an economically attractive st

45 show that genital infection with Schistosoma haematobium [corrected] may increase the risk for HIV in

46 y between 10% and 70% of WSH for reducing S. haematobium [corrected] transmission, our model predicte

47 valuated on a donor urine spiked with one S. haematobium egg and an array of other schistosomes and h

48 Schistosoma haematobium egg excretion rates showed a median reductio

49 S. haematobium egg injection triggered significant urotheli

50 articipants who had at least one Schistosoma haematobium egg observed on light microscopy from 10 mL

51 ion was defined via urine microscopy (>=1 S. haematobium egg) and urinalysis (haematuria).

52 Thus, S. haematobium eggs express IPSE homologs that appear to pe

53 matous responses to bladder-wall-injected S. haematobium eggs in Il4ra(-/-) versus wild-type mice.

54 ed optimal for extracting DNA from single S. haematobium eggs in spiked urine.

55 ltration technique was used to screen for S. haematobium eggs in urine samples.

56 y-intensity infections (ie, >=50 Schistosoma haematobium eggs per 10 mL of urine or >=400 Schistosoma

57 A single bladder exposure to S. haematobium eggs triggers interleukin-4 (IL-4) productio

58 icted in urothelial cells exposed only to S. haematobium eggs.

59 o bacterial UTI despite prior exposure to S. haematobium eggs.

60 out (Il4ra(-/-) ) and wild-type mice with S. haematobium eggs.

61 eripheral blood of children residing in a S. haematobium-endemic area and in the peripheral blood, sp

62 Women aged 15-35 years living in an S. haematobium-endemic area in Madagascar underwent pelvic

63 Venous blood from 72 Schistosoma haematobium-exposed participants was cultured with schis

64 zed by pooled serum samples from Schistosoma haematobium-exposed Zimbabweans were determined by 2-dim

65 tosomiasis due to infection with Schistosoma haematobium following recreational water exposure at Cap

66 Features of the S. haematobium genome that are conserved among platyhelmint

67 pecies with unusual interactions with the S. haematobium group parasites deserving of additional inve

68 say was robust, sensitive and specific to S. haematobium group species, detecting down to 10 fg of gD

69 snails, which are capable of transmitting S haematobium-group schistosomes.

70 Chronic infection with S. haematobium has been linked with bladder cancer and incr

71 d (3) the use of animal models to explore S. haematobium-host interactions.

72 tive species is probably an S. mattheei x S. haematobium hybrid.

73 The human parasitic fluke, Schistosoma haematobium hybridizes with the livestock parasite S. bo

74 ges to interrupt transmission of Schistosoma haematobium in a seasonal transmission setting of Cote d

75 Using the example of Schistosoma haematobium in Africa, this article illustrates how ecoz

76 cted Bulinus globosus, the snail vector of S haematobium in Malawi, were found at Cape Maclear and ot

77 S. haematobium-infected children and adolescents with bladd

78 S. haematobium-infected children with bladder pathology had

79 A greater percentage of B cells from S. haematobium-infected donors expressed cytoplasmic interl

80 level of interleukin 15 was lower in the S. haematobium-infected group (62.8 vs 102.9 pg/mL; adjuste

81 resulted in less IL-10(+) T cells in the S. haematobium-infected group, while levels of FoxP3(+) reg

82 re was a lack of treatment effects in the S. haematobium-infected group; however, the small sample si

83 lished study, which included 163 Schistosoma haematobium-infected individuals and 183 matched healthy

84 A Nigerian cohort of 168 Schistosoma haematobium-infected individuals and 192 healthy control

85 S. haematobium-infected schoolchildren were studied before

86 Schistosoma haematobium-infected schoolchildren were studied before

87 anemic children with documented Schistosoma haematobium infection (n = 224 for AGP, CRP, SF, sTfR, a

88 ctions in the prevalence and intensity of S. haematobium infection 1 year after treatment were, howev

89 with observed field patterns of Schistosoma haematobium infection and antibody responses, including

90 y that evaluates the relationship between S. haematobium infection and associated morbidity in childr

91 otherapy can have a substantial impact on S. haematobium infection and its associated morbidity in ch

92 r energy metabolism to be associated with S. haematobium infection and that EGR2 and EGR3, transcript

93 ular energy metabolism was associated with S haematobium infection and that the early growth response

94 in people with or without active Schistosoma haematobium infection and to determine whether this sign

95 We recruited women with and those without S. haematobium infection and women with and those without S

96 osed to increased TNF-alpha production to S. haematobium infection are more likely to develop an exag

97 lower interleukin 15 levels in women with S. haematobium infection as compared to those with S. manso

98 inal microbiome, and we hypothesized that S. haematobium infection could result in an alteration of i

99 C-ICTs to assess their ability to diagnose S haematobium infection from serum in a field-deployable f

100 We sought to determine whether women with S. haematobium infection had higher odds of high-risk human

101 Although Schistosoma haematobium infection has been reported to be associated

102 y was strongly predictive of Schistosomiasis haematobium infection in a nested cohort of 1976 primary

103 y outcome was prevalence and intensity of S. haematobium infection in children aged 9-12 years 1 year

104 d the efficacy of mefloquine IPTp against S. haematobium infection in pregnant women.

105 Overall, our analysis indicates that S. haematobium infection is associated with perturbations i

106 S haematobium infection is highly prevalent among expatria

107 ether bladder pathology in human Schistosoma haematobium infection is related to the balance of Th17

108 ws promising activity against concomitant S. haematobium infection leading to an important reduction

109 Schistosoma haematobium infection may impair female genital mucosal

110 Pregnant women with S. haematobium infection presenting at 2 antenatal health c

111 The primary outcome was S haematobium infection prevalence and intensity in 9-12-y

112 Removal of S haematobium infection resulted in increased schistosome-

113 Removal of S. haematobium infection resulted in increased schistosome-

114 in gene expression revealed clustering by S. haematobium infection status.

115 complex biological processes that connect S. haematobium infection to bladder carcinogenesis.

116 Schistosoma haematobium infection was positively associated with IgE

117 At baseline, higher intensities of S. haematobium infection were observed in children with ane

118 essed genes between those with or without S. haematobium infection when sex was included as a covaria

119 females without, particularly in Schistosoma haematobium infection, and a greater risk of death in HI

120 e risk of undernutrition and intensity of S. haematobium infection.

121 more than 50 eggs per 10 ml of urine for S. haematobium infection.

122 mucosa of 18 women with versus 39 without S. haematobium infection.

123 ell as differences in men and women, with S. haematobium infection.

124 en with different intensities of Schistosoma haematobium infection.

125 alent in cases with low-intensity urinary S. haematobium infection.

126 afebrile malaria, hookworm, and Schistosoma haematobium infection.

127 and intensity of Schistosoma mansoni and S. haematobium infections and to identify associated demogr

128 arm 2, and 167 (6.4%) of 2613 in arm 3 had S haematobium infections at baseline.

129 Both S. mansoni and S. haematobium infections occur in villages located along t

130 1.9%) of 3080 (1.3 [0.6-2.9]) in arm 3 had S haematobium infections.

131 Schistosoma mansoni (and rarely Schistosoma haematobium) intestinal infection is also not very commo

132 Schistosoma haematobium is a blood fluke that causes urogenital schi

133 Schistosoma haematobium is a parasitic helminth which causes urogeni

134 ract morbidity in areas in which Schistosoma haematobium is endemic.

135 nts from villages in rural Tanzania where S. haematobium is endemic.

136 Comparative genomics for S. haematobium is feasible, given the sequencing of multipl

137 Among the schistosomes, Schistosoma haematobium is responsible for the most infections, whic

138 Schistosoma haematobium is responsible for two-thirds of the world's

139 d, eyelids, and orbit, caused by Schistosoma haematobium is sporadic.

140 schistosomiasis, infection with Schistosoma haematobium, is linked to increased risk for the develop

141 nital schistosomiasis, caused by Schistosoma haematobium, is the most prevalent form of schistosomias

142 nth species and others that are unique to S. haematobium may provide novel diagnostic and drug target

143 Schistosoma mattheei nuclear and Schistosoma haematobium mitochondrial DNA, indicative of a hybrid sp

144 histosome species (Schistosoma mansoni or S. haematobium), number of treatment rounds, overall preval

145 Both S. haematobium (Odds ratio (OR): 4.7 [1.3-16.5], p=0.017) a

146 onward transmission of hybrid S. bovis x S. haematobium offspring within human populations.

147 d from cholangiocytes, in the presence of S. haematobium or S. mansoni eggs were investigated.

148 vical environment is impacted by Schistosoma haematobium or Schistosoma mansoni infection by quantify

149 ng anti-IL-10 added to PBMC from Schistosoma haematobium patients' enhanced adult worm (SWAP)- or egg

150 esearch into human coinfections (Schistosoma haematobium-Plasmodium falciparum versus Schistosoma man

151 urred 257-879 generations ago in northern S. haematobium populations.

152 ere evaluated of which 358 (34.1%) tested S. haematobium positive by the reference diagnostic standar

153 Biannual MDA substantially reduced the S haematobium prevalence and infection intensity but was i

154 terventions for the reduction of Schistosoma haematobium prevalence and infection intensity in childr

155 Sixty-four localities with a S. haematobium prevalence in school children aged 13-14 yea

156 By study end, we observed the lowest S. haematobium prevalence in the biannual MDA, compared to

157 For S haematobium, proteinuria (42 test comparisons, sensitivi

158 detection and quantification of Schistosoma haematobium provided by AiDx NTDx multi-diagnostic Assis

159 e most common human blood fluke, Schistosoma haematobium, responsible for approximately two-thirds of

160 were recruited from areas where Schistosoma haematobium (S.h) infections were high or low endemic.

161 Despite S. haematobium's importance, relevant research has lagged.

162 2 patients showed infection with Schistosoma haematobium, S haematobium-Schistosoma bovis hybrids, an

163 velers returned from Mali with a Schistosoma haematobium-Schistosoma bovis hybrid infection, confirme

164 ed infection with Schistosoma haematobium, S haematobium-Schistosoma bovis hybrids, and S bovis.

165 We aimed to screen the Schistosoma haematobium secretome to find antibody biomarkers of sch

166 t completely inhibited by CCDs, as well as S haematobium soluble egg antigen.

167 ance in each biofluid and exceeded that of S haematobium-soluble egg antigen in urine (AUC=0.79 [0.69

168 derivatives that kill both S. mansoni and S. haematobium, the two species responsible for >99% of sch

169 fective control strategy against Schistosoma haematobium transmission.

170 is context, we defined here the kinome of S. haematobium using a refined bioinformatic pipeline.

171 are orthologs of M-IPSE, from egg cDNA of S. haematobium Using PCR and immunodetection, we confirmed

172 SPR-assisted diagnostic test for Schistosoma haematobium, utilising recombinase polymerase amplificat

173 iagnosed via the Kato-Katz technique, and S. haematobium via urine centrifugation.

174 The prevalence S. haematobium was 0.83% (95%CI: 0.5-1.4) and that of haema

175 In contrast, S. haematobium was found in only a few villages in New Half

176 In the village where S. haematobium was prevalent, 110 genes were differentially

177 In contrast, the prevalence of Schistosoma haematobium was relatively low, with a rate of 2.1% in N

178 gene networks altered in the presence of S. haematobium We enrolled 33 participants from villages in

179 Cases of S. haematobium were detected only in three villages.

180 l disease caused by the parasite Schistosoma haematobium, which resides in the vasculature surroundin

181 enes are approaching fixation in northern S. haematobium with four genes potentially driving adaptati

182 million people are infected with Schistosoma haematobium, with the most intense infections in childre

183 hem was able to interrupt transmission of S. haematobium within a 3-year period.

184 ciated with increasing levels of Schistosoma haematobium worm IgG1, with adolescents with optical den

185 Urogenital schistosomiasis, Schistosoma haematobium worm infection, afflicts millions of people

186 eproducibly recovered significantly fewer S. haematobium worms and eggs from Mta1-/- mice than wild-t

187 ponse is stimulated by the death of adult S. haematobium worms and reduces worm fecundity.

188 schistosomiasis, infection with Schistosoma haematobium worms, remains poorly understood due to a hi

189 ract coinfection by bacteria and Schistosoma haematobium worms, the etiologic agent of urogenital sch