ライフサイエンスコーパス: have

1 Despite having 10% less lignin, CCR2(-/*) line 12 grows normally

2 me positive (>0.3 units) after resuscitation had 3-times higher risk compared to those who remained n

3 Most were Non-Hispanic White (86.3%) and had a college degree (64.3%).

4 At Week 48, DOR at 100 mg had a favorable safety profile compared with EFV or DRV+

5 Provider COC had a greater effect on end-of-life care expenditures th

6 Moreover, pyramidal neurons in A25 had a heightened density of NMDARs, which are the target

7 clusion, patients on aspirin and clopidogrel had a higher incidence of aspirin resistance than all pa

8 , children under 10 years of age and females had a lower incidence of SARS-CoV-2 infection than adole

9 contacts who received INH preventive therapy had a lower incidence of tuberculosis disease even when

10 lly sun-exposed skin (for example, the face) had a lower mutation burden than melanocytes from interm

11 Over a mean follow-up of 30 months, women had a lower risk of MACE (9.5% vs. 11.2%; adjusted hazar

12 antibodies, suggesting that M-tropic viruses had a macrophage origin.

13 ica particles, which were less intrusive and had a milder effect on membrane pore structure.

14 uction therapy (day 85), 29% of the patients had a molecular response, and this percentage increased

15 Women who did not receive chemotherapy had a more than 97% rate of 8-year freedom from distant

16 ive history of malignancy, while 19% of them had a positive history of breast cancer in first- or sec

17 None of the cases had a positive history of malignancy, while 19% of them

18 ion found that the Fusion and BioFire assays had a positive percent agreement (PPA) of 98.7%, followe

19 Three in 10 Medicare beneficiaries had a preexisting mental illness diagnosis, which was st

20 tients with bilateral infiltrates more often had a primary diagnosis of pneumonia (41% vs 28%; p = 0.

21 Vegetation and atmospheric water vapor also had a profound influence on the LST changes, but it had

22 -based biosensor for lactate detection which had a response time of less than 10 s over the range of

23 ograms with experience transplanting <23 SLs had a RR of 1.43 (1.21-1.75).

24 Acquired hospitals had a significant differential improvement in performanc

25 The temperature had a small effect on recovery, but significant differen

26 irus and found that the DUBmut-infected mice had a statistically significant reduction (P < 0.05) in

27 rsely proportional to age, such that frailty had a stronger adverse impact on younger patients.

28 Caffeine worsened and L-theanine had a trend of worsening inhibitory control (i.e. increa

29 cents were female, 81% were orphans, and 47% had a viral load of at least 1000 copies per muL.

30 In chronological order, I have a B.A. in Scandinavian languages and literature fro

31 ae of injection and other drug use, and they have a continuing role in addressing the opioid crisis a

32 establish that reachable-scale environments have a distinct representational signature from both sce

33 Allergists and clinical immunologists should have a leading role in this unprecedent challenge.

34 interface energy against Li, and they should have a low electronic conductivity and a high ionic cond

35 is were deemed to be minimal and unlikely to have a measurable physiological impact.

36 We have a mouse line with Tropomyosin receptor kinase B (Tr

37 cently, it was reported that AspH substrates have a non-canonical EGFD disulfide pattern.

38 is the leading cause of death in women, who have a notable increase in the risk for this disease aft

39 -CCY (all P > 0.05), but were less likely to have a previous C-section, gestational diabetes, preecla

40 ridae), a group of dynamic, swift predators, have a sparse fossil record, particularly at the time of

41 Thus, the propensity to overeat may have a strong innate component embedded in reward circui

42 negative regulator of Notch signaling, could have a suppressive role in T-ALL.

43 H was found to be positively associated with having a diagnosis of melanoma (odds ratio [OR] 5.01; 95

44 mmunochip improved sensitivity to 100% while having a lower specificity of 95.2% using a set of inves

45 In multivariate analyses, the odds of having A-HSIL were >6 times higher in women with anal hr

46 Breakthroughs in materials engineering have accelerated the progress of immunotherapy in precli

47 Here, we have addressed these questions in a series of genome-wid

48 We discuss how these errors have affected downstream analyses and give recommendatio

49 ls of mouse DC development and function that have aided in correlating ontogeny with function, as wel

50 ances in developmental and stem cell biology have allowed the development of cell-replacement therapi

51 long term neurological deficits in life and have also been associated with dysbiosis.

52 have nearly doubled global grain yields, but have also increased losses of reactive N to the environm

53 Only 0.86% of patients had an HZ-related hospitalization.

54 or at least 4 weeks before screening and who had an LDL cholesterol level of 130 mg per deciliter (3.

55 A total of 104 individuals had an RT-PCR-positive viral test with a cycle threshold

56 ion of mtFAS, as mutants lacking lipoylation have an intact ETC.

57 ylic acid-deficient Arabidopsis eds5 mutants have an unnoticed fah1-2 background mutation, which coul

58 GPR56 peptide agonists have antidepressant-like effects and upregulated AKT/GSK

59 Most previous models of quark nuggets have assumed no intrinsic magnetic field; however, Tatsu

60 79 (77%) of 102 in the ixekizumab Q2W group had at least one treatment-emergent adverse event.

61 VLNT and LVB have become increasingly popular in the treatment of lym

62 lastic abundances in freshwater environments have become more common in the past five years, but few

63 69 years, (IQR 25) and 62% male), 381 (62%) had been discharged alive, 178 (29%) died and 55 (9%) re

64 dence of tuberculosis disease even when they had been exposed to an index patient with multidrug-resi

65 lianas were not deeper-rooted than trees as had been previously proposed; and (3) evergreen trees ha

66 conserved Trp residues in the binding tunnel had been replaced with Ala.

67 Such soliton microcombs(10) have been applied to spectroscopy(11-13), the search for

68 Women have been at the forefront of tremendous achievements in

69 s, such as inhibition of plasmin generation, have been attributed to its main structural domains, the

70 rees can mimic this transpiration cycle, but have been confined to pumping water across a single micr

71 Many multi-parent populations have been constructed in crop species, and their inbred

72 They have been described in wines and the role of yeast in th

73 Imaging technologies have been developed to address these problems, but each

74 ment of the database, several flexible tools have been developed to aid retrieval and analysis of the

75 nsequently, in recent years research efforts have been directed towards modeling the structure and dy

76 erved core proteins within this architecture have been elucidated.

77 These data have been evaluated to provide practical considerations

78 proliferation, such as interleukin (IL)-15, have been explored as a means of boosting the antitumor

79 New materials have been explored, including green materials, but their

80 t lead halide perovskite nanocrystals, which have been extensively studied in the past 5 years, are m

81 e-based approaches in childhood cancers, few have been guided by biomarkers or clinical-grade assays

82 vel H1N2 influenza A viruses (IAVs) in swine have been identified in Chile co-circulating with pandem

83 t the thyroid hormone system, and major gaps have been identified in the tools available for the iden

84 urrent understanding of retinal changes that have been identified using advances in imaging technolog

85 tified, and the signaling pathways for cGAMP have been inferred to display a narrow distribution base

86 ly, prognostic outcomes of many cancer types have been linked with the expression levels of several o

87 fungi that share features with animals that have been lost in most other fungi.

88 There have been no multicountry field trials with liquefied pe

89 st described by our group in 2006, and there have been no subsequent reports of outcomes with this te

90 in the late-positive potential (LPP) window have been observed.

91 Cortical layer 1 (L1) interneurons have been proposed as a hub for attentional modulation o

92 Although neutralizing antibodies have been proposed as a potential key mechanism of prote

93 Early impairments to neurovascular coupling have been proposed to be a key pathogenic factor in the

94 s main structural domains, the kringles, and have been proposed to be mediated by their lysine-bindin

95 However, few community-based studies have been published and the true PeV infection burden is

96 enes (PSST1, PSST2, PSST3, PSST5, and PSST6) have been recently identified in elasmobranchs (Tostivin

97 nvolved in fear transmission within families have been scarcely investigated in humans.

98 n recent years, organic electronic materials have been shown to be a promising tool, even transplante

99 complications and preoperative patient risk have been shown to increase costs following surgery.

100 (sodium-glucose cotransporter 2) inhibitors have been shown to lower blood pressure, reduce weight,

101 Selection behaviors have been studied under several intersecting umbrellas i

102 ' extremely important roles, many major PTMs have been studied, while the functional and mechanical c

103 ons between distinct loci and various traits have been successfully discovered and published for the

104 fessional-administered oral hygiene measures have been suggested to play a dominant role in preventio

105 ions, in which unstable short-lived products have been synthesized and analyzed.

106 e, porous covalent organic frameworks (COFs) have been synthesized and structurally characterized.

107 Universal molecular markers have been used to identify these species, but insufficie

108 While safeners have been utilized for decades, knowledge of mechanisms

109 ly inaccessible chemical transformations and have been widely used in both academic and industrial se

110 s); 69% were BRCA1+, 30% were BRCA2+, and 2% had both mutations.

111 mediate additional immune functions that may have both protective and pathological consequences.

112 two carbon atoms of the L->C(2) complex both have carbene character.

113 To clarify this point, we have characterized the genomic landscape of 34 BI-ALCLs

114 We have combined X-ray absorption spectroscopic (XAS) finge

115 objectively measured physiological responses have commonly been used as a proxy for measuring subject

116 ular complexity and scale of the early liver have constrained analyses examining its emergence during

117 how functional genomics and reverse genetics have contributed to our understanding of this important

118 An abundance of swimming animals have converged upon a common swimming strategy using mul

119 In our cohort, 296 (2.1%) household contacts had coprevalent TB and 145 (1.9%) adult contacts develop

120 To ease this computational barrier, we have created a dynamic web-based platform, NASQAR (Nucle

121 Thirty patients were found to have cysts on initial imaging.

122 udinal distributions of neotropical migrants have decreased.

123 Prior studies have demonstrated that surgeons with lower peer-reviewed

124 OHTS DH had densitometric measurements more similar in magnitude

125 loss was "detected" if >= N(theta) clusters had deteriorated with p < p(Cluster), chosen empirically

126 on on a nucleosome and not just histones, we have determined the crystal structure of the LSD1/CoREST

127 femtosecond X-ray crystallography (SFX), we have determined the pristine structures of the Fe(III) a

128 To assess their affinity to PIPs we have developed a new cell free assay based on the abilit

129 Herein, we have developed a new strategy using proteins as structur

130 organic substrate and a chiral mediator, we have developed a transient-directing-group approach to r

131 In response, many diagnostic manufacturers have developed molecular assays for SARS-CoV-2 under the

132 Here we have developed monobodies, synthetic binding proteins, t

133 All participants had device interrogations performed before and after eac

134 a group of patients variously designated as having 'difficult to treat', 'treatment-resistant' or 'r

135 We have directly observed sub-gap states significantly lowe

136 Astronomers have discovered thousands of planets outside the Solar S

137 pidemiological studies from the last century have drawn strong associations between paternal life exp

138 ow sperm competition are therefore likely to have driven changes in relative testes size in opposing

139 DNA-encoded small molecule libraries (DELs) have enabled discovery of novel inhibitors for many dist

140 These technologies have enabled previously inaccessible chemical transforma

141 heless, in recent years considerable efforts have ensued to characterize alternative electrophiles th

142 , marine resource managers in many locations have established marine protected areas or seasonal clos

143 Recently, bacteriocins have even been used to treat cancer.

144 We have evidence supporting that E4BP4 may suppress the AMP

145 nontarget-site resistance (NTSR) mechanisms have evolved to most herbicide classes.

146 We have examined the priming of naive CD4 T cells in vitro

147 The forests of the HRL have experienced low human impact and still constitute l

148 a simpler, fourfold symmetric structure and have facilitated studies of the structural basis of chan

149 vious standard-of-care preventive treatments had failed.

150 ilst others (for example, Lythrum salicaria) had few.

151 tofilament, consistent with a single cofilin having filament-severing activity.

152 Most gene-environmental studies have focused on breast cancers generally, the prepondera

153 cturally related alkaloids, but most studies have focused on just two of these, mitragynine and 7-hyd

154 e potential opportunities that these devices have for the advanced sensing of pharmaceutical compound

155 (-1)), indicating meter sized crystals could have formed within days, if these rates are sustained th

156 Several studies have found that a more extensive lymphadenectomy leads t

157 Three-dimensional (3D) culture systems have fueled hopes to bring about the next generation of

158 Of 527 ineligible patients, 386 had full DST, of which 246 were resistant to ethambutol

159 agnostic criteria for GERD, while 107 (3.0%) had GERD associated with significant impairment of quali

160 We compared 16 patients who had GHPs showing neoplastic transformation with 39 patie

161 ns will address drug delivery challenges and have great potential to improve the efficacy of DSF-base

162 I have had the privilege to work in institutions in four d

163 h neonates with missing data were counted as having had a primary outcome event in the LMA group and

164 ry outcome event in the LMA group and as not having had such an event in the face-mask group.

165 These corals initially had heat-sensitive algal symbiont communities, endured b

166 has grown, greater amounts of molecular data have helped improve the ability to detect and track outb

167 ctors during the global re-methylation phase have high methylation levels prior to global de-methylat

168 ower peer-reviewed ratings of surgical skill had higher complication rates after bariatric surgery.

169 p of patients with a schizophrenia diagnosis had higher glutamate levels in thalamus (p = .01), but G

170 induced IFN-lambda levels (>90th percentile) had higher viral loads and were more likely to have resp

171 s demonstrated that (a) infants (<18 months) had higher virus-induced IFN-lambda airway secretion; (b

172 Some single-molecule studies have, however, suggested that the SOSIP trimer is not a

173 Poor SRH had HR 2.51 (CI: 2.19, 2.88).

174 Studies in experimental models and humans have identified 9 highly interconnected hallmark process

175 In this issue of Blood, Huang et al have identified activating transcription factor 4 (ATF4)

176 estigations focusing on GGGGCC-transcription have identified specific, canonical complexes that may p

177 We have identified three loci associated with neck or shoul

178 rmed under low temperature aqueous conditons have illustrated that these are excellent reservoirs to

179 Moreover, c3a.1(-/-) zebrafish larvae have impaired recruitment to localized bacterial infecti

180 These findings have implications for the molecular and cellular mechani

181 These studies have implications in furthering our understanding of JAM

182 Their findings have important implications to vaccine design.

183 Prph2K/+/Rom1+/- mice had improved rod and cone function compared with Prph2K/

184 Medium-chain fatty acids (MCFAs) have in rodents been shown to have protective effects on

185 Groups with late boosts had increased functionality and polyfunctionality scores

186 mmon cause of heart failure in young people, have increased during the last decades.

187 distributions of temperate-wintering species have increased while the latitudinal distributions of ne

188 gene encoding DNA polymerase epsilon (POLE) have incredibly high mutation burdens.

189 se with high cycle threshold are unlikely to have infectious potential.

190 t fractures displaced by 2 mm or less should have initial cast immobilisation, and any suspected non-

191 y, and catalytic improvement of carboxysomes have inspired rational design and engineering of new nan

192 All patients had laboratory confirmation of SARS-CoV-2 infection.

193 with pancreatic ductal adenocarcinoma (PDAC) have lagged behind advances made in the treatment of man

194 Studies thus far, however, have largely focussed on refolding full-length proteins

195 ring the past 85 years of antibiotic use, we have learned a great deal about how these 'miracle' drug

196 lood cultures (15.4% vs 45.1%; P = .005) and had less severe clinical presentations (median Pitt scor

197 We also found that herds with smaller K had less stochastic fluctuation in abundances around K,

198 severe symptom cutoff thresholds will likely have little impact on population levels of first-episode

199 but the arrays described in previous reports had low channel counts and required time-consuming manua

200 whole group of antipsychotic-naive patients had lower levels of GABA in dorsal ACC (p = .03), and th

201 )CD19(+)CD20(+)CD24(+)CD27(+)) were found to have lower abundance in PBC than in control.

202 th a higher proportion of Hispanic residents have lower B-CPR rates and lower survival.

203 ty is higher and for those where individuals have lower income per capita.

204 Herein, we have made a collection of literature which utilizes mult

205 nzymatic domain, we found that ULK1 and ULK2 have major differences in their autophagy-related intera

206 ing rest and movement in the GPi, which also had more beta desynchronization during movement.

207 le in abetting Coronary Heart Diseases (CHD) have mostly focused on deterrent health factors, like sm

208 Nitrogenous fertilizers have nearly doubled global grain yields, but have also i

209 All patients had neonatal/early-onset diabetes, severe microcephaly,

210 PrEP, 6% had used PrEP in the past, and 75% had never used PrEP.

211 d that would presumably exhibit lesser TMFs, had nine values among our compartments and organisms >1.

212 oplastic transformation with 39 patients who had non-neoplastic GHPs.

213 properties in failing human heart ventricles have not been examined for a circadian expression patter

214 nce signatures, ligands of shorter sequences have not been identified, together with many "orphan" re

215 ired for survival and proliferation in blood have not been identified.

216 ity to and severity of RSV disease in adults have not been well defined.

217 Such near-freezing temperatures have not previously been reconstructed from proxy data f

218 ding green materials, but their performances have not yet reached the level of that for fluoropolymer

219 rofound influence on the LST changes, but it had obvious difference in latitude.

220 Significant advancements have occurred in the ability to study sleep in dogs, inc

221 lt in organ dysfunction in aging and disease have often not been clarified.

222 Most electroretinography findings have pathognomonic features, but quantitative assessment

223 Invasive non-native species have pervasive impacts on native biodiversity, including

224 Indeed, several recent reports have pointed out spectacular differences in terms of int

225 e relatively robust to disorder and this may have practical ramifications.

226 ; 9 primary tumors, 34 recurrent tumors) who had preoperative (time before surgery: median, 23 d; ran

227 However, ADM-adjacent untreated sites which had presented with recession at baseline but were not tr

228 MRI was performed in all patients after having presented at our department for thoracic computed

229 We have previously shown that the ts residue signature of t

230 We have previously shown that this effect of leptin is medi

231 11 (12.9%) had primary glaucoma and 74 (87.1%) had secondary glauco

232 synthesis routes to produce such ceramic NWs have prohibitively high cost.

233 Although studies have proposed lineage heterogeneity within GMPs, it is u

234 acids (MCFAs) have in rodents been shown to have protective effects on glucose homeostasis during hi

235 Hereby, we have provided a tutorial for multivariate classification

236 Taken together, we have provided genetic, structural, and chemical evidence

237 Patients 10 to 17 years of age who had received stable lipid-lowering treatment for at leas

238 to the global "greening up." These programs have received worldwide attention due to its contributio

239 Contrary to this notion, we have recently demonstrated that these defective provirus

240 Multiple researchers have recently reported a linear relation between the car

241 injury compared to controls and the kidneys have reduced expression of the hypoxia-inducible erythro

242 From the total students diagnosed to have refractive error (n = 92), myopia constituted 83/92

243 wever, the causes of evolutionary constraint have remained elusive due to a poor mechanistic understa

244 the mechanisms behind this directed movement have remained uncertain.

245 the Treg-specific demethylated region (TSDR) have remained unchanged.

246 mula (A')(2) (A)(n) (-1) Pb(n) I(3) (n) (+1) have remarkable stability and promising efficiency in ph

247 d higher viral loads and were more likely to have respiratory sick visits within 12 months of dischar

248 Moreover, human cohort data have revealed differential DNA methylation signatures in

249 n subcellular structures and organelles that have rotational symmetry.

250 Thirteen patients were identified to have RRD within 3 months of intravitreal injection.

251 hown to lower blood pressure, reduce weight, have salutary effects on left ventricular remodeling, an

252 (12.9%) had primary glaucoma and 74 (87.1%) had secondary glaucoma.

253 (1%) of 427 patients in the adalimumab group had serious infections.

254 e design was observational, 21 of 36 studies had serious ROB, and publication bias was possible.

255 tive when initiated early in illness but can have serious side effects.

256 nce with existing meta-analyses, and studies had several methodological shortcomings.

257 ved from human pluripotent stem cells, which have several advantages over fetal cell-derived therapie

258 ecent years, genome-wide association studies have shed light on the genetics of early growth and its

259 ater than DNA sequence changes and typically have short half-lives of two to three generations.

260 Genome-wide association studies have shown many variants are found within putative enhan

261 In conclusion, we have shown that anti-ADAMTS13 autoantibodies from iTTP p

262 al studies investigating the drivers of LLPS have shown that intrinsically disordered proteins (IDPs)

263 Many recent studies have shown that the integration of gene expression and p

264 gery (44.6% vs. 46.6%), 8 diabetes remitters had significant reductions in WBC and platelet counts wh

265 Altogether, flavonoids could have significant prophylactic value for retinal degenera

266 at storm drains, bromeliads and garbage cans had significantly more pupae in relation to larvae when

267 Both LF and NF groups had similar demographics, valve areas and indices.

268 Anti-IL-10-treated nonhuman primates had similar overall disease outcomes compared with untre

269 the context of small-molecule catalysts has had sizable impact on the field of asymmetric catalysis

270 measurements showed that humidified systems have slower real time water diffusion compared to anhydr

271 Though common variants individually have small effects on disease risk, GWAS provide a power

272 The fact that we have so many materials opens many exciting avenues but a

273 =30) were treated with the same schedule and had sparse dolutegravir pharmacokinetic sampling at week

274 icare reimbursement rates in general surgery have steadily decreased from 2000 to 2018.

275 ed that activations emerge spontaneously and have strong similarities to task-evoked activations(e.g.

276 Two variants, DAD2(N242I) and DAD2(F135A), having substitutions in the core alpha/beta hydrolase-fo

277 ple reductive quenching photoredox cycle, we have successfully harnessed this novel radical strain-re

278 nfluenza vaccines that target the HA protein have suffered resistance due to destabilizing HA mutatio

279 Here we have systematically studied Zn(2+) inhibition of AMPARs

280 Typically, such investigations have taken a 'black box' approach in which the internal

281 Though several hundred clinical trials have tested immune-based approaches in childhood cancers

282 previously proposed; and (3) evergreen trees had the deepest roots, which is necessary to maintain ca

283 Furthermore, fish-free feed had the highest degree of in-vitro protein hydrolysis an

284 l extract, whereas the ethyl acetate extract had the highest inhibitory effect on heat-induced protei

285 Biology students had the highest prevalence of GORD symptoms (63% - 127/2

286 Mammalian cells have the ability to incorporate thymidine analogs along

287 dy used for preventing asthma exacerbations) have the potential to circumvent steroid sensitivity pat

288 We have trained a machine learning model to analyze the cor

289 ted ART after 2.3 months of age, one of whom had two identical intact sequences, suggestive of a cell

290 Studies in recent years have uncovered the crucial function of neuroimmune inter

291 borated in stress-susceptible male mice that have undergone chronic social defeat stress, a mouse mod

292 )1.7-specific and Na(V)1.8-specific blockers have undergone clinical trials, with others in preclinic

293 in species-rich Mycalesina butterflies that have undergone parallel radiations in Africa, Asia, and

294 ative MSM, 19% were currently using PrEP, 6% had used PrEP in the past, and 75% had never used PrEP.

295 nstrate the feasibility of this approach, we have used the antihistamine agent loratadine (1).

296 protein (CSP) variants of P. vivax, besides having variations in the protein repetitive portion, can

297 cted celiac disease who are seronegative but have villous atrophy and genetic risk factors for celiac

298 Our results have wide-ranging implications for optimising antitrypan

299 No activators of cGAMP signaling have yet been identified, and the signaling pathways for

300 extensive peat bogs of Southern Scandinavia have yielded rich Mesolithic archaeological assemblages,