ライフサイエンスコーパス: have been elucidated

1 ing nor the molecular mechanism of switching had been elucidated.

2 erved core proteins within this architecture have been elucidated.

3 g with the interaction of nkx2.7 with tbx20, have been elucidated.

4 mechanisms of NK activation postvaccination have been elucidated.

5 iated, and many of its underlying mechanisms have been elucidated.

6 SUMO elicits its effects on target proteins have been elucidated.

7 y which autophagy operates in these contexts have been elucidated.

8 systems, few of its developmental functions have been elucidated.

9 hways that lead to Th17 cell differentiation have been elucidated.

10 functional roles of key residues and motifs have been elucidated.

11 pment and functioning of the auditory system have been elucidated.

12 ignaling in an androgen-depleted environment have been elucidated.

13 e TTF and newly formed triazole ring systems have been elucidated.

14 allene ether version of the Nazarov reaction have been elucidated.

15 grees C, and details of the reaction pathway have been elucidated.

16 nor its link to the progression of apoptosis have been elucidated.

17 ts on TLR signaling of several of these SNPs have been elucidated.

18 the genesis of dyslipidemia and hypertension have been elucidated.

19 ction against primary sclerosing cholangitis have been elucidated.

20 hat directly control V(H) gene rearrangement have been elucidated.

21 eraction between parasite and mammalian host have been elucidated.

22 ructures of these in complex with chitinases have been elucidated.

23 inetic contributions to stability or folding have been elucidated.

24 agents in simple ferric salt cross-couplings have been elucidated.

25 nd the major biochemical mechanisms involved have been elucidated.

26 s and mechanisms of these signaling pathways have been elucidated.

27 ch intron and the intron/exon junctions also have been elucidated.

28 mitosene (2,7-DAM), the major MC metabolite, have been elucidated.

29 lopment of a hyperexcitable neuronal network have been elucidated.

30 ecognition sites on AsiA and final sigma(70) have been elucidated.

31 half of them, binding sites on this collagen have been elucidated.

32 as zinc ligands and in binding and catalysis have been elucidated.

33 es of ulcerative colitis and Crohn's disease have been elucidated.

34 identified, and the mechanisms of cell entry have been elucidated.

35 e structures that alter CD44 affinity for HA have been elucidated.

36 nt of DNA polymerase I from Escherichia coli have been elucidated.

37 molecular regulators of retinal phagocytosis have been elucidated.

38 y complex RiPPs, very few biosynthetic steps have been elucidated.

39 s)(2)][NTf(2)], solid-state X-ray structures have been elucidated.

40 ic fates of these molecules in the cytoplasm have been elucidated.

41 s that drive proliferation nor their sources have been elucidated.

42 itating the emergence of pathogenic bacteria have been elucidated.

43 yte, and hydrogen bond donor species effects have been elucidated.

44 termining ring closure on enantioselectivity have been elucidated.

45 on efficiency and its transformation pathway have been elucidated.

46 lished specific genetic risk factors for CAD have been elucidated.

47 7, or either of these proteins with a kinase have been elucidated.

48 tosol to trigger activation of NOD1 and NOD2 have been elucidated.

49 molecular mediators of tamoxifen resistance have been elucidated.

50 t to lie outside the reducing range of SmI2, have been elucidated.

51 local connectivity, and parallel processing have been elucidated.

52 of the relevant adaptive traits and variants have been elucidated.

53 lopathies that underlie cardiac arrhythmias, have been elucidated.

54 f drugs, discovered by phenotypic screening, have been elucidated.

55 nor the molecular mechanisms underlying them have been elucidated.

56 , and their underlying molecular mechanisms, have been elucidated.

57 athways that promote cell fate specification have been elucidated.

58 transplantation treatment for this disorder have been elucidated.

59 for CoM biosynthesis in methanogenic archaea have been elucidated, a complete pathway for the biosynt

60 subcellular roles of many individual kinases have been elucidated, a comprehensive assessment of the

61 While multiple critical genes and pathways have been elucidated, a genome-wide analysis of gene exp

62 though possible underlying mechanisms of PTH have been elucidated, a substantial void remains in our

63 y have been known for some time, few details have been elucidated about changes that occur as a resul

64 monogenetic and complex polygenic disorders have been elucidated and functionally characterized.

65 of the biochemical steps of the PAO pathway have been elucidated and genes encoding many of the chlo

66 cribe characteristics of this chemistry that have been elucidated and how this chemistry may be utili

67 al abnormalities underlying these conditions have been elucidated and novel enzyme defects continue t

68 lecular contacts at the active site of FIH-1 have been elucidated and provide a platform for future d

69 The crystal structures of these receptors have been elucidated and reveal hydrogen bonding in the

70 ions of many previously uncharacterized COGs have been elucidated and tentative functional assignment

71 pathogenesis, the roles of several cytokines have been elucidated and tested in both preclinical anim

72 logy of pain transmission within the cranium have been elucidated, and advances been made into the pa

73 In the heart, elegant molecular pathways have been elucidated, and derangements in these pathways

74 defects underlying many of these conditions have been elucidated, and great progress has been made t

75 matory cascade underlying allergy and asthma have been elucidated, and IgE is now known to play a key

76 mical signaling pathways for these responses have been elucidated, and recent evidence points to the

77 he genetic bases for some of these disorders have been elucidated, and signaling pathways required fo

78 nteraction of these bacteria with their host have been elucidated, and the murine model of cystitis h

79 mammalian target of rapamycin (mTOR) pathway have been elucidated as driver mutations in ovarian carc

80 access, tumor biology, and cancer management have been elucidated as possible reasons for disparities

81 While specific functions of zinc have been elucidated at a molecular level in a number of

82 gh numerous direct neural targets of cocaine have been elucidated at the molecular level, little is k

83 (TF)-target gene binding relationships that have been elucidated at the molecular level.

84 asing numbers of plant biosynthetic pathways have been elucidated based on approaches utilizing genom

85 iron and sulfur loading onto monomeric ISCU2 have been elucidated biochemically, yet subsequent [2Fe-

86 which 8 E6 increases mutations caused by UV have been elucidated, but less is known about how 8 E6 i

87 molecular players mediating this interaction have been elucidated, but only a few works have studied

88 several features of copper binding to LPMOs have been elucidated, but the identity of the reactive o

89 ric acid- and levamisole-sensitive receptors have been elucidated, but the levamisole-insensitive ace

90 ays of the disassembly of the different MCCs have been elucidated, but the mode of their regulation r

91 matodes, globally acting regulatory pathways have been elucidated, but the more tissue- and organ-spe

92 plex formed by the oligonucleotide d(G3T4G3) have been elucidated by a combination of high-resolution

93 Sound British Columbia, and their structures have been elucidated by analysis of NMR and MS data.

94 The structures of the new dhilirolides have been elucidated by analysis of spectroscopic data a

95 Molecular mechanisms have been elucidated by biochemistry and structural biol

96 les of function for light-gated ion channels have been elucidated by creating channelrhodopsins with

97 hydride reduction of endocyclic iminium ions have been elucidated by density functional theory calcul

98 ly has a unique structure, features of which have been elucidated by DFT calculations.

99 ter partial chondroitin ABC lyase digestion, have been elucidated by disaccharide analysis, liquid se

100 ways underlying the effects of phytohormones have been elucidated by genetic screens and hypothesis-d

101 The photophysics have been elucidated by intensity-dependent correlation

102 roles of the three proteins present in mice have been elucidated by KO models, but the function of t

103 les from aqueous solutions of SnCl(4).5H(2)O have been elucidated by means of in situ X-ray total sca

104 n of alcohols by chiral pyridine derivatives have been elucidated by measurements of relative rates f

105 The circulation patterns for such systems have been elucidated by microearthquakes and geochemical

106 ues have been obtained, and their structures have been elucidated by NMR spectroscopy and X-ray cryst

107 iamine-based Trost 'Standard Ligand' (R,R)-1 have been elucidated by NMR, isotopic labeling and compu

108 The biological roles of DNA methylation have been elucidated by profiling methods based on whole

109 nal features of factor XIII and fibrin(ogen) have been elucidated by protein and gene analysis, site-

110 The functions of many cellular proteins have been elucidated by selective gene inactivation and

111 tion to increased levels of dietary peptides have been elucidated by studying the response to the sub

112 len)-catalyzed epoxidation by peracetic acid have been elucidated by the density functional [Becke th

113 rafficking and their roles in Cu homeostasis have been elucidated by the studies of model microorgani

114 acteristics of aromatic and aliphatic phases have been elucidated by the use of linear solvation ener

115 d truncated bacteriophage T4 gene 32 protein have been elucidated by two independent and sensitive me

116 l cycle regulation of Caulobacter crescentus have been elucidated by using defined unmethylated or he

117 solid-state structural features of 12 and 17 have been elucidated by X-ray crystallographic methods.

118 opy, and the molecular structures of 6 and 8 have been elucidated by X-ray crystallography.

119 ), 3-Cp*, 3-(t)Bu, 4-Cp*, 4-(t)Bu, and 5-Cp* have been elucidated by X-ray crystallography.

120 The structures of the porphyrins have been elucidated by x-ray diffraction analysis, and

121 high-resolution structures of these channels have been elucidated, capturing their dynamic conformati

122 er, few molecular details for turion biology have been elucidated due to the difficulties in isolatin

123 al structures of the C-terminal domain of A1 have been elucidated, each in complex with a nanobody as

124 From this database there have been elucidated elements of recognition rules that

125 the structural biology of the Pap CU pathway have been elucidated, except for the C-terminal domain o

126 Some determinants of Zn(2+) binding have been elucidated experimentally and in computational

127 Important roles for autophagy have been elucidated for cell survival during nutrient i

128 s, as well as inventories of affected genes, have been elucidated for deletions of AZFa and of AZFc b

129 While many details have been elucidated for how the cytosol and endoplasmic

130 Although chemical mechanisms have been elucidated for many enzymes, the question of h

131 Contributions to O(2) activation have been elucidated for non-heme relative to heme ligan

132 the genetic factors predisposing to obesity have been elucidated for several rare syndromes, the fac

133 Two distinct mechanistic pathways have been elucidated for stoichiometric reactions of the

134 bulins (acid and basic), whose 3D structures have been elucidated for the first time in Vitis vinifer

135 Crystal structures have been elucidated for the M(pro) complexes with each

136 Several biochemical functions have been elucidated for them, and notably, MAGEs regula

137 Only a few functionally significant residues have been elucidated for this enzyme, as well as for the

138 nection with details of the mechanism, which have been elucidated from kinetics, site-directed mutage

139 atomic or near-atomic resolution structures have been elucidated from various in vitro and ex vivo o

140 cellular determinants of heart regeneration have been elucidated, how injury triggers a regenerative

141 sms mediating genotoxic NF-kappaB activation have been elucidated, how this signalling is terminated

142 taxa inhabiting deep-sea hydrothermal vents have been elucidated; however, the physicochemical facto

143 growth and differentiation of the allantois had been elucidated in whole embryos.

144 While size control mechanisms have been elucidated in a number of other organisms, it

145 ecific differences in floral color and scent have been elucidated in a variety of plant genera, the g

146 ases in which the roles of individual miRNAs have been elucidated in behaving animals.

147 to conscious perception at a cortical level have been elucidated in both animals and humans.

148 reductions of structures with functions that have been elucidated in commonly studied mammalian speci

149 e involved in atmospheric particle formation have been elucidated in controlled laboratory studies of

150 uction of cyclic strain into cellular events have been elucidated in cultured vascular cells.

151 e endoplasmic reticulum (ER) stress response have been elucidated in detail in many eukaryotic organi

152 mechanisms of rRNA transcription regulation have been elucidated in great detail, the functional org

153 tential (TRP) channels, particularly as they have been elucidated in heterologous expression systems.

154 In plants, cysteines have been elucidated in maintaining protein folding and

155 principles of chromatin remodelling as they have been elucidated in non-plant systems and to discuss

156 functions of such polyadenylated transcripts have been elucidated in only a few examples.

157 (IGF-1R) and estrogen receptors (ERs), which have been elucidated in other systems, have yet to be ex

158 ly involved in the response to these changes have been elucidated in recent years and will be the sub

159 of the budding yeast G1-S transition (Start) have been elucidated in recent years, especially with re

160 ed by bacterial and oomycete plant pathogens have been elucidated in recent years, information for th

161 cal excision of introns and joining of exons have been elucidated in recent years, the signaling path

162 genesis and neurovascular barrier maturation have been elucidated in recent years.

163 , and dihydroxylated compounds, are degraded have been elucidated in recent years.

164 criptional level, and several major pathways have been elucidated in recent years.

165 s in asynchronous insect flight muscle (IFM) have been elucidated in situ using multiple approaches.

166 Although mechanisms of miRNA biogenesis have been elucidated in some detail, there is limited ap

167 The WhiA/B regulons and binding sites have been elucidated in Streptomyces venezuelae (Sven),

168 ular adsorbates on transition metal surfaces have been elucidated in the context of chemical catalysi

169 rising connectivities and diverse mechanisms have been elucidated in the development of these reactio

170 These two hypotheses of genetic control have been elucidated in the literature.

171 of the TLR-mediated cell signaling pathways have been elucidated in the past few years, the molecula

172 ve been identified, and molecular mechanisms have been elucidated in yeast.

173 onic MPN phenotype to acute myeloid leukemia have been elucidated, including deletion of the transcri

174 derlying methicillin resistance in S. aureus have been elucidated, including regulatory events and th

175 The initial steps in DSB formation have been elucidated, involving cytosine deamination by

176 own, and the deregulated downstream pathways have been elucidated, it will be possible to identify vu

177 he physiological roles of non-CG methylation have been elucidated, its direct impact on transcription

178 Although many of c-MYC's functions have been elucidated, its effect on the presentation of

179 gh molecular pathways of this underexcretion have been elucidated, its etiology remains mostly unknow

180 lthough early stages of invadopodia assembly have been elucidated, little is known about maturation o

181 ough some aspects of HSV-1 chromatin biology have been elucidated, many epigenetic factors controllin

182 ral steps in MPO biosynthesis and processing have been elucidated, many questions remained, such as t

183 ereas the events responsible for its release have been elucidated, mechanisms regulating the nuclear

184 many features of the translocation mechanism have been elucidated, molecular details of LPS insertion

185 h the structures of many DNA binding domains have been elucidated, no detailed structures are yet ava

186 isms for iron entry and storage within cells have been elucidated, no system to mediate iron efflux h

187 tal structures of alpha - and beta -phosgene have been elucidated on the basis of variable temperatur

188 improvement; however, gold-standard genomes have been elucidated only for modern temperate varieties

189 ents of the hair-cell transduction apparatus have been elucidated only recently.

190 iological dimensions of cultural transitions have been elucidated only to a limited extent so far.

191 de of action of this virulence master switch have been elucidated, others remain unsolved.

192 As the complexities of dystrophic pathology have been elucidated over the last few years, it has bec

193 regarding the coevolution of bats and moths have been elucidated over the past 50 years.

194 The underlying biochemical pathways have been elucidated over the past decades, yet the mech

195 sms for sensing mechanical and chemical cues have been elucidated over the past three decades, the me

196 hilic members of the family whose structures have been elucidated previously.

197 ction of inositol hexakisphosphate (InsP(6)) have been elucidated recently.

198 Furthermore, new details have been elucidated regarding the morphology and physio

199 perception, and signaling of these hormones have been elucidated, revealing the variety of mechanism

200 l structures of all three HIF-alpha proteins have been elucidated, revealing their bHLH and tandem PA

201 gh the general sortase-associated mechanisms have been elucidated, several structural attributes uniq

202 very few anthraquinone biosynthetic pathways have been elucidated so far, including the enzymatic dim

203 r which the structure-property relationships have been elucidated so far.

204 several singular dietary glycan-induced PULs have been elucidated, studies on the unusually high numb

205 The roles of miRNAs in CRC have been elucidated, subsequent to recent studies that

206 selectivity of the cyclopropanation process have been elucidated such that selective access to a wid

207 endent mechanisms of TF-induced angiogenesis have been elucidated that may signal through distinct pa

208 including innervation and taste acquisition, have been elucidated, the early patterning signals drivi

209 involved in synthesis of core and O-antigen have been elucidated, the effect of removing O-antigen a

210 ly steps in the biosynthesis of homoterpenes have been elucidated, the identity of the enzyme respons

211 ally induces catastrophic immune destruction have been elucidated, the important role that miRNAs pla

212 e for bacterial translocation into the heart have been elucidated, the initial interactions of heart-

213 Although CaMKIIalpha functions have been elucidated, the isoform-specific catalytic fun

214 oth open and closed states of the proteasome have been elucidated, the mechanism by which gates excha

215 he pathway regulating sexual differentiation have been elucidated, the mechanism of Sry action within

216 Although genetic and cell biological aspects have been elucidated, the molecular details of HP1 bindi

217 Although some embryological pathways have been elucidated, the molecular etiologies of ASD ar

218 onents of the class I MHC processing pathway have been elucidated, the participation of nonproteasoma

219 PQQ biosynthesis, involving PqqD/E and PqqC, have been elucidated, the precise nature and order of th

220 hile the processes driving T-IEL development have been elucidated, the precise roles of the different

221 lization of individual germ plasm components have been elucidated, the process by which germ plasm as

222 numerous hallmarks of age-related microglia have been elucidated, the progression from homeostasis t

223 g the generation of phenotypic heterogeneity have been elucidated, the speed with which identical sis

224 ar determinants of Th17 cell differentiation have been elucidated, the transcriptional programs that

225 eterminants of this metabolic transformation have been elucidated, their broad biological implication

226 everal Hdacs in bone development and biology have been elucidated though in vitro and in vivo models.

227 and binding to MHC class II HLA-DR molecules have been elucidated through a combination of peptide st

228 Further clues to its regulation have been elucidated through biosynthetic pathway determ

229 etagogue stimulation of pancreatic secretion have been elucidated through characterization of the Src

230 a+/ myo-inositol cotransporter (SLC5A3) gene have been elucidated through cloning, sequencing, mRNA a

231 The growth processes have been elucidated through experiments that probe dire

232 The structure and function of ion channels have been elucidated through high-resolution x-ray struc

233 amics of pathway complexity in self-assembly have been elucidated through kinetic models based on agg

234 echanism and microstructure of the nanotubes have been elucidated through SEM, STEM, HAADF-STEM tomog

235 al hemoglobin (HbF) regulation and switching have been elucidated through studies of human genetic va

236 Many useful principles of self-assembly have been elucidated through studies of systems where mu

237 en the ring expansion reactions of 1b and 1c have been elucidated through the calculation of the ener

238 ated ubiquitination and degradation of HMGCR have been elucidated through the study of cultured mamma

239 ed sequences for damage formation and repair have been elucidated, thus making it possible to identif

240 ndent optimization of plasma protein binding have been elucidated to achieve suitable effective half-

241 f those plant and algal polysaccharides that have been elucidated to date.

242 endelian disorders, only about half of which have been elucidated to date.

243 ors that participate in patterning the heart have been elucidated (Tu and Chi, 2012), the cellular ev

244 been separated by HPLC, and their structures have been elucidated unambiguously by NMR spectroscopy,

245 nal disease, and although initiation factors have been elucidated, uncertainty concerning the downstr

246 The global kinetics have been elucidated under four sets of conditions, and

247 Their electronic structures have been elucidated using a host of physical methods, i

248 redox oxidative C-O coupling, the mechanisms have been elucidated using density functional theory (DF

249 Structures of all the compounds have been elucidated using IR, NMR, MS, and elemental an

250 The structures of all of the compounds have been elucidated using IR, NMR, MS, and elemental an

251 chanisms of action of interventional devices have been elucidated using IVUS, and ultrasound is used

252 dy the genes regulated by MucR in B. abortus have been elucidated using microarray analysis and real-

253 tioselective oxidation of secondary alcohols have been elucidated using quantum mechanics (B3LYP DFT

254 ue lipid-protein interaction mechanisms that have been elucidated using SPR.

255 Key miRNA regulation features that have been elucidated via modelling include: (i) the role

256 some cases, the mechanisms of these effects have been elucidated, while other mechanistic functions

257 ation of 3-5 and their electronic structures have been elucidated with DFT calculations.

258 ry responsible for cellular self-destruction have been elucidated with unprecedented celerity during

259 cology of the soybean aphid in North America have been elucidated, with economic thresholds, sampling

260 ex and simple retroviruses and retroelements have been elucidated, with the exception of the gammaret

261 uctural biology of the peptidoglycan pathway have been elucidated, with the exception of the PNGM str

262 Many pathways regulating blood formation have been elucidated, yet how each coordinates with embr