ライフサイエンスコーパス: healing

1 s (e.g., cancer, heart attack, stroke, wound healing).

2 at coalesce into clots which assist in wound healing.

3 n and phenotypic changes in cancer and wound healing.

4 be reactivated and play roles in adult wound healing.

5 cally and/or electronically facilitate wound healing.

6 microcurrent electrotherapy on palatal wound healing.

7 2(Cre+)) resulted in improved diabetic wound healing.

8 inflammation, cell proliferation, and wound healing.

9 ed, showing rapid vacancy migration and self-healing.

10 for Zn alloys when considering bone fracture healing.

11 ro slows keratinocyte migration during wound healing.

12 d IL-6 levels associated with improved wound healing.

13 injury and subsequently improving aged bone healing.

14 anscriptional landscape that influence wound healing.

15 ensure efficient, spatially restricted wound healing.

16 rotein 1 (LRG1) in normal and diabetic wound healing.

17 lular creatine, barrier formation, and wound healing.

18 lerated the bone repair early from 7 days of healing.

19 ifferentiation and HO formation during wound healing.

20 raluminal polyamines that promote epithelial healing.

21 tissues results in delayed wound closure and healing.

22 MaR1 potently accelerated extraction socket healing.

23 stabilize the injury site and promote wound healing.

24 omotes epithelial barrier function and wound healing.

25 critical for embryonic development and wound healing.

26 rovide a new therapeutic avenue for fracture healing.

27 trix (ECM) production, chemotaxis, and wound healing.

28 noncoding RNA (lncRNA) KCNQ1OT1 in fracture healing.

29 that affected invasion, migration, and wound healing.

30 nocytes (Mo)/macrophages (MPhi) and impaired healing.

31 with MaR1 delivery versus vehicle on socket healing.

32 lline periodicity and display efficient self-healing.

33 sed by Pseudomonas aeruginosa and poor wound healing.

34 an potentially be targeted for enhancing DFU healing.

35 and have at least two key roles in scar-free healing.

36 sion, and the same might be useful for wound healing.

37 mosome ends are recapped by de novo telomere healing.

38 cy of ARP as compared with unassisted socket healing.

39 s crucial to embryonic development and wound healing.

40 beta (TGFbeta) play a critical role in wound healing.

41 thin the wound bed to overcome stalled wound healing.

42 on integrins, cellular migration, and wound healing.

43 the NPWT system in order to accelerate wound healing.

44 hanges in collagen organization during wound healing.

45 dicating a potential important role in wound healing.

46 tendon environment as the driver of scarless healing.

47 )-derived coatings to regulate scar-mediated healing.

48 ell dispersion, neuronal survival, and wound healing.

49 n the animal studies indicate a proper wound healing.

50 acteristics that might reproduce pASCs wound healing ability.

51 ither a provisional crown (test) or standard healing abutment (control) after immediate implant place

52 uncovered and connected to the corresponding healing abutments.

53 derivatives showed promising in vitro wound-healing activity.

54 Long-term bone healing/adaptation after a dental implant treatment star

55 esacral abscess formation and perineal wound healing after APR, while it increases the likelihood of

56 the achievement of histo-endoscopic mucosal healing after induction therapy is associated with lower

57 d leukocytes in the diseased heart, improved healing after infarction and attenuated heart failure.

58 compare the healing outcome between natural healing after molar tooth extraction and two different t

59 We conclude that early healing after orthopaedic trauma must be allowed prior t

60 on the efficacy and safety of various wound healing agents to improve chronic diabetic wounds.

61 reting hMSC lines as short-term, local wound healing agents with superior therapeutic efficacy over w

62 Following 2 to 8 months of healing, all implants were uncovered and connected to th

63 ectric crystalline lattice that enables self-healing and a reprogrammable stiffness for dynamic tunin

64 th types of microglia significantly improved healing and axon regrowth.

65 voir of bioactive molecules to support wound healing and bone regeneration.

66 and keloid scars result from abnormal wound healing and can have a variable response to a number of

67 tained cell migration is essential for wound healing and cancer metastasis.

68 re of collagen type I is a hallmark of wound healing and cancer that is commonly attributed to myofib

69 We report on in vitro wound-healing and cell-growth studies under the influence of r

70 herapy protocol may accelerate palatal wound healing and decrease patient discomfort after FGG harves

71 ks that might apply to both cancer and wound healing and discuss how wounding, as in biopsy and surge

72 nective tissue deposition, suggesting vessel healing and durable vessel occlusion.

73 oft and hyperextensible skin, abnormal wound healing and easy bruising.

74 ells, which are active participants in wound healing and fibrogenic processes.

75 ix protein that has important roles in wound healing and fibrosis.

76 so doing, to promote barrier function, wound healing and hair growth, while limiting cancer developme

77 ribosomal proteins, and initiation of wound healing and humoral immune responses.

78 lial homeostasis, tissue regeneration, wound healing and immune modulation.

79 le in organ development and repair, in wound healing and in numerous pathological processes such as c

80 been associated with decreased bone fracture healing and increased rates of nonunion in elderly patie

81 ent and impaired inflammation impedes tissue healing and is a characteristic of chronic wounds.

82 ned from the significant literature on wound healing and macrophage response to implanted biomaterial

83 Wound healing and Matrigel invasion assay, sphere formation as

84 Besides applications to wound healing and metastatic cancer, these studies are relevan

85 icantly reduce both corneal epithelial wound healing and nerve density in diabetic mice.

86 show that Hdac3 is required for optimal bone healing and osteoclast fusion, potentially via its regul

87 ng developmental stages, angiogenesis, wound healing and other processes.

88 and to uncover mechanisms that prevent wound healing and regeneration in mammals.

89 nflammatory process and perhaps initiate the healing and regeneration process of the periodontium.

90 properties play an important role in tissue healing and regeneration, activation of TLR3 may help to

91 popularity in the field of periodontal wound healing and regeneration.

92 nderlying angiogenesis, fertilization, wound healing and regeneration.

93 in) plays an important role in cardiac wound healing and remodeling.

94 lts cancer progression as a result of tissue healing and remodelling of the blood vasculature, causin

95 in collaboration with the Collaborative for Healing and Renewal in Medicine (CHARM) network, the aut

96 ding in Hydra, suggesting that Hydra's wound-healing and self-organization capabilities may employ si

97 insights into the process of diabetic wound healing and suggest topical mast cell stabilization as a

98 he angiogenic process during cutaneous wound healing and the regulatory roles played by catecholamine

99 tion dynamics that regulate subsequent wound healing and tissue regeneration are still unclear.

100 e resolution phase of inflammation, bridging healing and tissue regeneration.

101 sponses, activities that contribute to wound healing and tissue repair.

102 o pathway-focused RT-PCR gene arrays ("wound healing" and "neurogenesis") to evaluate tissue samples

103 The short- (bone healing) and long-term (bone remodeling) effects of init

104 fragility, wrinkles, laxity, impaired wound healing, and a microenvironment conducive to cancer.

105 oles in hemostasis, tumor development, wound healing, and atherogenesis.

106 ed at the inflammation stage of murine wound healing, and bone marrow-derived cells served as a major

107 sticity, stretchability, self-recovery, self-healing, and energy dissipation.

108 n the involvement of adipose tissue in wound healing, and may help to uncover and develop fat-related

109 f fibroblast heterogeneity during skin wound healing, and on open questions that must be addressed to

110 ears cutaneous bacterial infection, promotes healing, and protects against reinfection.

111 cular abnormalities, poor postinfection lung healing, and subsequent pulmonary failure.

112 nesis is one of such critical events in bone healing, and we previously reported the stimulatory effe

113 nflammatory, anticancer, antidiabetic, wound healing, anti-HIV, anti-anxiety and antidepressant, etc.

114 the challenges inherent to therapy-mediated healing are due to comorbidities of disease and aging th

115 Two mechanisms of self-healing are identified: viscoelastic shape memory (VESM)

116 /cell delivery, thrombus ablation, and wound healing are reviewed from these viewpoints.

117 ntroduced for analyzing a standardized wound healing assay by observing cell growth and quantifying c

118 The wound-healing assay demonstrated that, at concentrations of 0.

119 ents of cell proliferation, apoptosis, wound healing assay, as well as reverse-phase protein arrays,

120 Using an in vitro wound healing assay, cell migration was evaluated 2, 4, 6, and

121 Subsequent in vitro wound-healing assays also confirmed that M2 and M13 accelerate

122 aluated on sparse real-world data from wound healing assays with varying initial cell densities [2].

123 by intracellular calcium measurements, wound healing assays, and synthetic activation by gene array a

124 or inflammatory diseases and defective wound healing associated with aging and diabetes.

125 entage of study participants with epithelial healing at 3 days, 3 weeks, and 3 months, infiltrate or

126 are active processes that mediate epithelial healing at mucosal surfaces.

127 ts suggest that Gal-3 is essential for wound healing because it regulates the dynamics of macrophage

128 wound: proportion of newly formed bone (bone healing/BH), number of cells stained for tartrate-resist

129 prague-Dawley rats were extracted, and after healing, bilateral periodontal defects were surgically c

130 and its up-regulation is required for wound healing but is also involved in fibrosis.

131 rmal processes such as development and wound healing, but can go awry, as in oncogenesis and fibrosis

132 ethods have shown promise in monitoring bone healing, but no quantitative method to assess regenerate

133 ibrotic effects are of promise for improving healing by balancing the primary defensive functions and

134 been recently described to accelerate wound healing by enhanced keratinocyte migration and indirect

135 kpile of adenosine, resulting in accelerated healing by promoting both osteoblastogenesis and angioge

136 r surgery or traumatic injury, corneal wound healing can cause a scarring response that stiffens the

137 l plasticity underlying embryogenesis, wound healing, cancer metastasis and drug resistance.

138 s that occurs during tissue formation, wound healing, cancerous invasion, and viral infection.

139 hase with a high interfacial energy and self-healing capabilities, development of "anode-free" Li bat

140 Moreover, a decrease in wound healing capacity in hTERT-MCPyV gene-expressing HK was o

141 erapeutic capability to motivate canonically healing cells toward improved behavior; enhancing our ab

142 ientists must be particularly vigilant about healing claims that lack solid foundational data.

143 e and mouse models of angiogenesis and wound healing confirmed these predicted deficiencies and demon

144 t roles of fibroblasts in ECM biology, wound healing, diseases, and aging.

145 Perpetual cycles of wounding and healing drive fibrosis in DDEB and RDEB, as well as the

146 isol, which is responsible for delayed wound healing during a systemic excess of GC.

147 M13-NL) demonstrated excellent in vivo wound-healing effects, and these activities were better than t

148 The wound healing efficacy of the fabricated dressings was evaluat

149 development of hydraulically amplified self-healing electrostatic (HASEL) actuators, a new class of

150 Striking similarities between wound healing, epimorphic regeneration and the progression of

151 During wound healing, expression of AP-1B (and ARH in AP-1B-positive

152 obstruction of vascular invasion during bone healing favours chondrogenic over osteogenic differentia

153 ocesses such as embryonic development, wound healing, fibrosis and cancer.

154 Roth's Large (MRL/MpJ) mice exhibit improved healing following acute tendon injuries, but the driver

155 demonstrate functional improvements to bone healing following local beta-NGF injections which result

156 regates, and CDN-dictated stiffness and self-healing functions of hydrogels.

157 cludes innovative anomaly detection and self-healing functions that improve the efficiency of data pr

158 ificant upregulation of SERPINB1 and IL33 in healing gingiva.

159 8 to 10 weeks) or long-term (18 to 20 weeks) healing group.

160 cells (ASCs) have potential to improve wound healing; however, their equivalents from domestic animal

161 udy is the first to report on the miRNome of healing human gingiva and to provide an integrative anal

162 s ranging from recyclable thermosets to self-healing hydrogels.

163 The primary clinical endpoint was lesion healing (ie, full epithelialisation or stable scar) with

164 and lower tumour necrosis factor-alpha), pro-healing immune profiles (high insulin-like growth factor

165 their regenerative potential, and improving healing in a complex tissue environment.

166 ment with miR-19b and miR-20a improved wound healing in a mouse model of type 2 diabetes.

167 ium cobalt oxide cathode to achieve dendrite healing in a practical full-cell device.

168 cts of MaR1 on tooth extraction socket wound healing in a preclinical rat model.

169 this work we report the acceleration of self-healing in alternating/random hydrophobic acrylic-based

170 ducing bacterial load and accelerating wound healing in an excisional wound model.

171 ibute to sustained inflammation and impaired healing in chronic wounds.

172 Mast cells have been shown to regulate wound healing in diabetes.

173 eceptors promotes angiogenesis and expedites healing in diabetic wounds.

174 that Hdac3 promotes M2 activation and tissue healing in inflammatory conditions.

175 ory function of WDR26 in FPR1-mediated wound healing in intestinal epithelial cells.

176 ich negatively regulates FPR1-mediated wound healing in intestinal epithelial cells.

177 and their combination significantly hastened healing in ischemic methicillin-resistant Staphylococcus

178 e, an osteoanabolic agent that improves bone healing in preclinical studies and in chronic periodonti

179 der Waals (vdW) forces which facilitate self-healing in relatively narrow copolymer compositional ran

180 Furthermore, the rapid and consistent wound healing in seedling grafts along with lateral shoot form

181 s that could be used to facilitate scar-free healing in the adult mammalian nervous system.

182 key contributor to intestinal mucosal wound healing in vivo.

183 d of neointimal coverage and completeness of healing, including endothelialization.

184 Outcome variables were early healing index (EHI) at 7, 14, and 30 days, self-reported

185 , CEACAM1, and VCAM1), called the endoscopic healing index [EHI], using samples from 278 patients wit

186 Wound healing is characterized by cell and extracellular matri

187 Delayed wound healing is commonly associated with diabetes.

188 However, the soft tissue healing is technically sensitive to the surgical procedu

189 The healing is triggered by current-controlled, self-heating

190 r, the influence on peri-implant soft tissue healing is unclear.

191 expression in three settings: in vitro wound healing, live lymph node sections and a live tumor micro

192 perties for covalent materials, such as self-healing materials, covalent adaptable networks (CANs) an

193 g from sensing to molecular release and self-healing materials.

194 The concept may be applicable to other self-healing mechanisms involving reversible covalent bonding

195 Since two autonomous self-healing mechanisms result from viscoelastic behavior not

196 tural photosystems exhibit a variety of self-healing mechanisms.

197 technique, grafting materials, postoperative healing, medications used postoperatively, bone growth,

198 In an excisional wound healing model, i.p. MV administration accelerated wound

199 Using an endoscopic biopsy-based wound healing model, we report that RvE1 is locally produced i

200 ding area to the center in an in vitro wound healing model.

201 Improvement in mechanical properties of healing MRL/MpJ vs C57Bl/6 tendons that were isolated fr

202 and 2 diabetic full-thickness splinted wound healing murine model enhanced the microcirculatory blood

203 u beams show high robustness and have a self-healing nature.

204 healthy volunteers to study effects on wound healing (NCT04045405; NCT03603431).

205 In development of an embryo, healing of a wound, or progression of a carcinoma, a req

206 The healing of broken chromosomes by de novo telomere additi

207 es bone morphogenic protein 2 (BMP2) driving healing of calvarial defects in 4 weeks by a mechanism m

208 Hdac3 within myeloid progenitors accelerates healing of cortical bone defects.

209 he management of angiogenesis to promote the healing of dermal wounds.

210 d human dental pulp stem cells (DPSC) on the healing of experimental periodontal defects in rats.

211 difference in the amount of shrinkage during healing of free soft tissue autografts (FSTAs) using dif

212 The healing of large bone defects has been investigated for

213 CN allowed the healing of NK in all patients as well as improvement of

214 on-skin electronics demonstrates accelerated healing of skin wounds.

215 errupt that process and encourage growth and healing of the "baby lung" of severe acute respiratory d

216 At 1 week, healing of the 15 sites was uneventful.

217 ing the 12-month follow-up period to promote healing of the fracture.

218 s of atherosclerotic complications favor the healing of wounded arteries, whereas the immobilization

219 this mechanism in studies in vivo, in wound healing or angiogenesis, in which fibrin is contracted b

220 tissue shares features with mammalian wound healing or fibrosis.

221 nt, which we called histo-endoscopic mucosal healing (or histo-endoscopic mucosal improvement).

222 een achieved in creating biodegradable, self-healing, or breathable, on-skin electronics.

223 the multivariate parameters critical to self-healing organic fluorophore design.

224 hort study was to histologically compare the healing outcome between natural healing after molar toot

225 on-sutured sites display similar early wound healing outcomes and patient-reported outcomes.

226 y aimed to determine and compare soft tissue healing outcomes following implant placement in grafted

227 three from the nSG during the first week of healing (P >0.05).

228 icit anti-inflammatory responses and promote healing, pathways ending with cell membrane rupture may

229 ported outcomes were assessed during a 14-wk healing period.

230 l changes in SA and thickness over a 3-month healing period.

231 threads differentiated into bone during the healing phase but resorbed during remodeling.

232 ts of initial implant micromotion during the healing phase were studied.

233 sue types were modeled as poroelastic in the healing phase.

234 nd non-covalent bonding chemistries for self-healing polymers, an ultimate goal is to create high str

235 of microglia in neonatal mice disrupts this healing process and stalls the regrowth of axons, sugges

236 emoattraction of cells critical to the wound healing process, eCRT induces abundant neo-dermal extrac

237 ry of small molecules to improve the post-MI healing process.

238 variety of immunological reactions and wound healing process.

239 r their potential to contribute to the wound healing process.

240 lling determine outcomes of inflammation and healing processes.

241 As wound healing progresses, the collagen organization dramatical

242 ing point for the development of novel wound-healing promoters.

243 an element used for adding strength and self-healing properties to load-bearing materials.

244 r compositions can significantly impact self-healing properties.

245 , 2.5, and 5 mM) significantly reduced wound healing rates, whereas nicotine at a concentration of 10

246 Reduced wound healing ratios and nerve densities were not fully rescue

247 for 8 and 20 weeks, respectively) had slower healing ratios than wild-type diabetic mice.

248 mmune system is inextricably linked to wound healing/remodeling in the ischemically injured heart, th

249 provides an opportunity to examine a normal healing response and an aberrant fibrotic response withi

250 onclusion, we demonstrate that an endogenous healing response can be safely induced in tendon by mean

251 Therefore, the wound-healing response in the infarct area typically yields sc

252 njuries, but the driver of this regenerative healing response remains unknown.

253 hus due to an acute inflammatory-based wound-healing response that rejuvenates the infarcted area of

254 at while most of the gland underwent a wound-healing response that resolved by day 14, a small region

255 ells(3,4) and has a beneficial role in wound-healing responses(5,6).

256 ne marrow cells is required for normal wound healing, revealing a physiological role for this glycopr

257 e was an inverse association between mucosal healing risk of future small bowel adenocarcinoma (HR, 0

258 ally evaluate healing (using photographs and Healing Score Index) on Days 1, 5, 14, and 21.

259 oreover, the conservative measure of corneal healing showed statistical significance at week 4 (key s

260 eviously demonstrated that chick fetal wound healing shows a regenerative phenotype regarding the cel

261 itude, resulting in an increase of the wound-healing speed of up to 135 +/- 85% as compared to an int

262 randomized clinical pictures, then assessed healing status conventionally (<0.5 mm of fluorescein st

263 Pro-healing stent coatings may facilitate reendothelializati

264 year in the US, methods to promote fracture healing still rely primarily on fracture stabilization,

265 iRNA/mRNA expression during human oral wound healing; the results offer novel insights into the parti

266 ity of SERPINB1 and IL-33 as potential wound healing therapeutic targets.

267 ndothelial cells, it accelerates endothelial healing through activation of nuclear ERalpha in smooth

268 NF-kappaB may contribute to fibrotic tendon healing through both inflammation-dependent and inflamma

269 icit of Gal-3 affected the dynamics of wound healing, thus aggravating the evolution of remodeling an

270 ar on each mandibular quadrant (Day 0); bone healing time (week14); placement of four rough-surface e

271 By survival curve analysis median healing time for cure was 102 for Sb v group and 60 days

272 d to increase the cure rate and decrease the healing time.

273 t often damages host cells and lengthens the healing time.

274 sulfate are reported and correlated with the healing time.

275 protein-based adhesives and fibers in wound healing, tissue regeneration, drug delivery, biosensors,

276 re fibroblastic cells that function in wound healing, tissue repair and fibrosis, and arise from bone

277 lds have great potential for improving wound healing treatments by providing controlled drug delivery

278 elp to uncover and develop fat-related wound healing treatments.

279 feration, colony formation, migration, wound healing, tumor growth, and lung metastasis.

280 fibers and films capable of autonomous self-healing under ambient conditions.

281 nt, increased bacterial killing and improved healing upon a secondary infection.

282 were left undisturbed to clinically evaluate healing (using photographs and Healing Score Index) on D

283 emphasis on perioperative infections, wound healing, vascular complications, cancer propagation, as

284 d fibrosis through the temporal evolution of healing, ventricular remodeling, and function after myoc

285 hus, cDC2s promote itching during skin would healing via a TGF-beta-IL-31 axis with implications for

286 Wound-healing was also impaired in PSW compared to controls at

287 Clinical healing was documented.

288 were created using an Algerbrush, and wound healing was monitored over time.

289 the LCD1 patients, corneal epithelial wound healing was significantly delayed in TGFBI-R124C mice.

290 Soft tissue healing was uneventful in all patients.

291 associated with skin blood supply and wound healing were altered.

292 s in normal dermal wounds and thereby delays healing, whereas the stimulation of dopamine D1 receptor

293 is an essential step during cutaneous wound healing, which supports cells at the wound site with nut

294 provides a brief overview of cutaneous wound healing with discussion on how extracellular matrix prot

295 ion resembling the remodeling phase of wound healing, with increased matrix metalloproteinase express

296 vely removed without scarring, with complete healing within 2 weeks.

297 es were found for complicated perineal wound healing within 30 days (RR 1.30; 95% CI 0.92-1.82), chro

298 ient in a vicious cycle characterized by non healing wounds and malnutrition.

299 Non-healing wounds have placed an enormous stress on both pa

300 stant Staphylococcus aureus infected delayed healing wounds in rats with DM2.