ライフサイエンスコーパス: hearing impairment

1 birth defects, ranging from microcephaly to hearing impairment.

2 ty of a link between K(v)1.1 dysfunction and hearing impairment.

3 normal hearing listeners and other forms of hearing impairment.

4 within 19 genetic intervals associated with hearing impairment.

5 or a substantial proportion of patients with hearing impairment.

6 vere thyroid hormone deficiency and profound hearing impairment.

7 d can be a significant burden for those with hearing impairment.

8 135G>T [p.Glu379X]) in ILDR1 as the cause of hearing impairment.

9 rlying nonsyndromic prelingual sensorineural hearing impairment.

10 of the mechanisms of hypothyroidism-induced hearing impairment.

11 th an increased risk of substantial neonatal hearing impairment.

12 ner ear histology suggestive of a conductive hearing impairment.

13 e unit (NICU), and one of them had bilateral hearing impairment.

14 thyroid hormone dysregulation in age-related hearing impairment.

15 vating neurons is the most frequent cause of hearing impairment.

16 d neural system of the inner ear, leading to hearing impairment.

17 nd travel, among individuals who also have a hearing impairment.

18 ing a person's susceptibility to age-related hearing impairment.

19 s in cochlear hair cells, and thus relate to hearing impairment.

20 t heterozygous mice do not suffer peripheral hearing impairment.

21 d with a higher likelihood of developing any hearing impairment.

22 w of the genetic architecture of age-related hearing impairment.

23 molecular mechanisms underlying hearing and hearing impairment.

24 autosomal dominant, nonsyndromic hereditary hearing impairment.

25 universal neonatal screening programmes for hearing impairment.

26 egated with the inherited autosomal dominant hearing impairment.

27 a conditioning tone, perhaps attributable to hearing impairment.

28 characterized by congenital mild-to-moderate hearing impairment.

29 at least 30 autosomal loci for nonsyndromic hearing impairment.

30 vement in immobility, visual impairment, and hearing impairment.

31 sclerosis is the single most common cause of hearing impairment.

32 ry disorder that causes hypopigmentation and hearing impairment.

33 characterized by congenital mild-to-moderate hearing impairment.

34 0 of these children have moderate or greater hearing impairment.

35 111 out of 287 participants had hearing impairment.

36 brillation, cancer, asthma, and deafness and hearing impairment.

37 ccine compared with adults with little to no hearing impairment.

38 hearing impairment, and 121 (4%) had severe hearing impairment.

39 1 in 4 people worldwide will be living with hearing impairment.

40 ccine compared with adults with little to no hearing impairment.

41 ese myosins in patients suffering visual and hearing impairment.

42 normal hearing or mild, moderate, or severe hearing impairment.

43 hypertonia, visual problems, and conductive hearing impairment.

44 egenerate after damage, leading to permanent hearing impairment.

45 pumps, OHCs degenerate, leading to profound hearing impairment.

46 uced myelination might augment sensorineural hearing impairment.

47 idneys, diabetes, hepatitis, depression, and hearing impairment.

48 sleep deprivation, immobility and visual and hearing impairment.

49 l hearing and 7 with bilateral sensorineural hearing impairment.

50 deficit, cerebral palsy, or severe visual or hearing impairment.

51 RP) with or without congenital sensorineural hearing impairment.

52 CNS mechanisms are affected by a peripheral hearing impairment.

53 icity in the perceptual sequelae of cochlear hearing impairment.

54 gic disease, brain lesions, drug effect, and hearing impairment.

55 ptors of the auditory system re-emerges with hearing impairment.

56 ign of damage in both noise- and age-related hearing impairment.

57 oaches and medical care for LF patients with hearing impairment.

58 r, and prognostic indicator, for age-related hearing impairment.

59 , indicating hair cell dysfunction and gross hearing impairment.

60 in a socially excluded group of people with hearing impairment.

61 examined a clinical cohort of subjects with hearing impairment.

62 tation had symmetric, mild-to-moderate mixed hearing impairment.

63 isk for psychosis is observed in people with hearing impairment.

64 r diagnosis of cerebral palsy and visual and hearing impairments.

65 studies in older humans when controlling for hearing impairments.

66 s that cause severe prelingual non-syndromic hearing impairments.

67 e fibers, can lead to profound and permanent hearing impairments.

68 ls to the auditory nerve leads to undetected hearing impairments.

69 cues, posing challenges for individuals with hearing impairments.

70 00), IGF-1 was associated with lower odds of hearing impairment (0.86; 0.73, 1.00) after adjustment f

71 v lomustine monotherapy 29% of patients) and hearing impairment (24% v 0%).

72 missense variants in PLCG1 who present with hearing impairment (5/7), ocular pathology (4/7), cardia

73 ants had normal hearing, 1170 (40%) had mild hearing impairment, 692 (23%) had moderate hearing impai

74 Hearing impairment, a common treatable condition, may co

75 he appropriate compensation of sensorineural hearing impairment across a range of frequencies (e.g.,

76 ous for KARS mutations had symmetric, severe hearing impairment across all frequencies but did not sh

77 family with autosomal dominant nonsyndromic hearing impairment (ADNSHI) was enrolled in this study.

78 Genetic hearing impairment affects around 1 in every 2,000 birth

79 Hearing impairment affects many older adults but is ofte

80 [aHR], 1.89; 95% CI, 1.57-2.28), functional hearing impairment (aHR, 1.14; 95% CI, 1.00-1.31), and f

81 ter than the effects of vision impairment or hearing impairment alone, because when these two sensory

82 Its potential for permanent hearing impairment also emphasizes the need to better un

83 protective effects on hypothyroidism-induced hearing impairment, an F1 intercross was generated betwe

84 improvement indices of 0.21 (P = 0.008) for hearing impairment and 0.26 (P < 0.001) for mobility imp

85 n leads to the DFNA17 phenotype (progressive hearing impairment and cochleosaccular degeneration) rem

86 ) did not attenuate the associations between hearing impairment and cognition (global cognition: unst

87 Although association between hearing impairment and dementia has been widely document

88 recent intense interest in the link between hearing impairment and dementia, comprehension of acoust

89 uated and considered in future management of hearing impairment and design of auditory prostheses.

90 l hearing), adjusted for the severity of the hearing impairment and for maternal education.

91 the middle ear, is the most common cause of hearing impairment and surgery in children.

92 ion are advancing molecular understanding of hearing impairment and the complex mechanisms of the aud

93 screening for permanent bilateral childhood hearing impairment and the effects of confirmation of he

94 Variables, including hearing impairment and the presence of visual and other

95 an pathology including retinal degeneration, hearing impairment and type 2 diabetes.

96 mammalian vertebrates can fully recover from hearing impairments and balance dysfunctions because sup

97 ications for pitch perception in people with hearing impairments and cochlear implants.

98 search tool that can elucidate the nature of hearing impairments and suggest or eliminate compensator

99 d hearing impairment, 692 (23%) had moderate hearing impairment, and 121 (4%) had severe hearing impa

100 e outcomes of disability and death combined, hearing impairment, and adverse events.

101 deprivation, immobility, visual impairment, hearing impairment, and dehydration.

102 , rheumatoid arthritis, thyroid dysfunction, hearing impairment, and handgrip strength).

103 suffered from pancytopenia, allergy, asthma, hearing impairment, and mental retardation.

104 sability, facial and skeletal abnormalities, hearing impairment, and mild immune deficiency.

105 children aged 6-19 years have some degree of hearing impairment, and over 216,000 of these children h

106 cluding microcephaly, neurological deficits, hearing impairment, and vision loss.

107 iovascular disease, itself a risk factor for hearing impairment, and, in animal studies, molecular ev

108 OC, innervation, which likely contributes to hearing impairments, and a relative paucity of MOC termi

109 a range of adverse listening conditions and hearing impairments, and even for users of cochlear impl

110 , cognitive impairments, vision impairments, hearing impairments, and motor impairments) using compre

111 Both cardiovascular disease risk and hearing impairment are associated with cognitive dysfunc

112 sms by which cardiovascular disease risk and hearing impairment are collectively associated with cogn

113 is unfolding as genes underlying hereditary hearing impairment are identified.

114 People with hearing impairment are thought to rely heavily on contex

115 Age-related hearing impairment (ARHI) affects 25-40% of individuals

116 Age-related hearing impairment (ARHI) is the most common sensory imp

117 Age-related hearing impairment (ARHI), or presbycusis, is the most p

118 damage to the inner ear is a major cause of hearing impairment, arising from exposures occurring dur

119 within the autosomal-recessive nonsyndromic hearing impairment (ARNSHI) locus DFNB68 on 19p13.2.

120 ciated with autosomal-recessive nonsyndromic hearing impairment (ARNSHI), was mapped to chromosomal r

121 ate the ability of the dSHS to help rule out hearing impairment as a cause or confounder in clinical

122 ever, Mcu(-/-) mice displayed high-frequency hearing impairment as early as 3 weeks postnatal, which

123 bjects (8%) and 0 of 13 control subjects had hearing impairment, as did 1 nonrandomized subject.

124 e to the aetiology of amblyaudia, a binaural hearing impairment associated with bouts of otitis media

125 dulthood, corresponding with the early onset hearing impairment associated with Mass1frings.

126 formation of the heart and other organs, and hearing impairment associated with recurrent ear infecti

127 Hearing impairment at baseline was defined as a pure ton

128 Hearing impairment at birth was also less frequent in th

129 onates, both groups with no risk factors for hearing impairment at birth, were included.

130 ng loss gene, has been linked to age-related hearing impairment before, and in addition is preferenti

131 mpairment and the effects of confirmation of hearing impairment by nine months of age on subsequent v

132 Confirmation of hearing impairment by nine months of age was associated

133 Modern screening tests for hearing impairment can improve identification of newborn

134 family members in three generations: 10 with hearing impairment caused by the DFNA23 locus, 8 unaffec

135 Developmental hearing impairments compromise sound discrimination, spe

136 ogical abnormalities of the external ear and hearing impairment (conductive or sensorineural) affect

137 fects, but three of 11 surviving infants had hearing impairment confirmed on auditory testing between

138 la syndrome include cataracts, sensorineural hearing impairment, congenital heart disease, jaundice,

139 as immobility, functional decline, visual or hearing impairment, dehydration, and sleep deprivation a

140 or mobility impairment), sensory (visual or hearing impairments), developmental (intellectual or dev

141 (DFNB2), and autosomal-dominant nonsyndromic hearing impairment (DFNA11).

142 have been linked to non-syndromic hereditary hearing impairment DFNA17 as well as 'MYH9-related disea

143 me type IB, autosomal-recessive nonsyndromic hearing impairment (DFNB2), and autosomal-dominant nonsy

144 characterized by a pigmentation anomaly and hearing impairment due to lack of melanocyte.

145 ice, in contrast, present with non-syndromic hearing impairment due to the effects of multiple genes

146 Hearing impairment due to the loss of sensory hair cells

147 t of listening effort may thus help diagnose hearing impairment earlier.

148 the lesions but no new hair cells arise and hearing impairment ensues.

149 nt such that hyperglycemia in the context of hearing impairment exacerbated poor performance on learn

150 holistic approaches to health management and hearing impairment, (f) universal access to evolving and

151 In participants with hearing impairment, faster rates of whole brain atrophy

152 iption cofactor Eyes absent 4 (Eya4), causes hearing impairment followed by dilative cardiomyopathy.

153 a reduced likelihood of functional recovery: hearing impairment, greater increase in postsurgical dis

154 associated with functional recovery, whereas hearing impairment, greater increases in postsurgical di

155 categorized into normal (BPTA <=25 dB), mild hearing impairment (>25 to 40 dB), and moderate or great

156 ment (>25 to 40 dB), and moderate or greater hearing impairment (>40 dB).

157 US population, and prevalences of vision and hearing impairment have been extensively evaluated.

158 Age-adjusted prevalence of hearing impairment (HI) decreased across generations in

159 Congenital hearing impairment (HI) is a genetically highly heteroge

160 Hearing impairment (HI) is prevalent, is modifiable, and

161 d or absent for listeners with sensorineural hearing impairment (HI).

162 #267300) often associated with sensorineural hearing impairment; however, mice with a knockout mutati

163 ry, smoking, body mass index, and vision and hearing impairment (HR = 1.05, 95% CI = 1.03-1.07, p < 0

164 tudied 120 children with bilateral permanent hearing impairment identified from a large birth cohort

165 reduced hearing ability and the duration of hearing impairment in 42 unilateral hearing loss (UHL) p

166 0 on screening for age-related sensorineural hearing impairment in adults aged 50 years or older with

167 ions and 2) modifiable factors contribute to hearing impairment in adults.

168 which may have changed temporal patterns of hearing impairment in adults.

169 The condition began with high-frequency hearing impairment in all family members excluding III:2

170 effect of birth cohort on the prevalence of hearing impairment in an adult population aged 45-94 yea

171 as performed for 273 participants and showed hearing impairment in at least 1 ear, most commonly mild

172 tations in the POU domain gene Brn-3c causes hearing impairment in both the human and mouse as a resu

173 OM remains the most common cause of hearing impairment in childhood.

174 otic capsule are common causes of conductive hearing impairment in children and adults.

175 Because CSOM is the commonest cause of hearing impairment in children in these countries, an ef

176 the duration of MEE and possible concomitant hearing impairment in children with AOM.

177 iants co-segregates with congenital profound hearing impairment in consanguineous Pakistani families

178 mtDNA mutations predisposing to hearing impairment in humans are generally homoplasmic,

179 activating protein, is implicated in causing hearing impairment in humans.

180 tated the identification of genes that cause hearing impairment in humans.

181 icate that the short nose, otitis media, and hearing impairment in Jacobsen syndrome are likely becau

182 we link a previously uncharacterized gene to hearing impairment in mice and humans.

183 of candidate genes to late-onset progressive hearing impairment in mouse and human.

184 F) recommendation statement on screening for hearing impairment in older adults.

185 l function are important contributors to the hearing impairment in Pit1(dw) mice.

186 1 appeared to confer some protection against hearing impairment in some older adults warrants replica

187 aring loss (NSHL) is the most common type of hearing impairment in the elderly.

188 lea accounts for a significant proportion of hearing impairment in the population.

189 o national guidelines, and the prevalence of hearing impairment in the two groups was compared by usi

190 The prevalence of hearing impairment in these neonates was determined, wit

191 amily with X-linked postlingual nonsyndromic hearing impairment in which the critical linkage interva

192 the genetic and physiological bases of human hearing impairment, including both early- and late-onset

193 a range of adverse listening conditions and hearing impairments, including cochlear implant-supporte

194 , TR beta 2-null mice exhibit no evidence of hearing impairment, indicating that TR beta 1 and TR bet

195 Hearing impairment is 1 of the 4 most prevalent chronic

196 Given that the frequency of all childhood hearing impairment is 1/1,000 and that half of that is g

197 There are >400 disorders in which hearing impairment is a characteristic of the syndrome,

198 Pediatric hearing impairment is a chronic handicap that can potent

199 Hearing impairment is a common human condition, but we k

200 Functional simulation of sensorineural hearing impairment is an important research tool that ca

201 vous system symptoms, visual disturbance and hearing impairment is an oft-encountered clinical scenar

202 As newborn screening for hearing impairment is being implemented in many birth ho

203 Hearing impairment is clinically and genetically heterog

204 Hearing impairment is common in adults with diabetes, an

205 Although hearing impairment is common in patients with mtDNA defe

206 This is of importance as age-related hearing impairment is highly prevalent in our ageing soc

207 genetic deafness is non-syndromic, in which hearing impairment is not associated with any other abno

208 of middle ear effusion (MEE) and concomitant hearing impairment is not known.

209 Hearing impairment is one of the most common sensory def

210 mporal resolution in listeners with cochlear hearing impairment is presented with the aim of assessin

211 autosomal dominant late-onset non-syndromic hearing impairment is segregating, we have identified a

212 Hearing impairment is the most common sensory deficit.

213 Hearing impairment is the most common sensory disorder,

214 Late-onset non-syndromic hearing impairment is the most common type of neurologic

215 Severe deafness or hearing impairment is the most prevalent inherited senso

216 ion.The full extent of the genetic basis for hearing impairment is unknown.

217 the link between IGF-1 and the occurrence of hearing impairment is untested in population-based studi

218 ied mutation in CABP2 that causes a moderate hearing impairment likely via nonsense-mediated decay of

219 y, a novel autosomal recessive non-syndromic hearing impairment locus DFNB44 was mapped to chromosome

220 Hearing impairment may be a modifiable risk factor for d

221 It is currently unclear whether hearing impairment may impair the ability to use selecti

222 generation and a moderate but nonprogressive hearing impairment, mimicking the visual and hearing def

223 hich were not included in prior risk models: hearing impairment, mobility impairment, weight loss, an

224 for blindness (0.9% vs 0%; P = .02), and for hearing impairment (moderate and severe, 0.9% vs 0%; P =

225 d when exposed to asymmetrical mild-moderate hearing impairment, more specifically on the ipsilateral

226 sifiable category where 67.2% had documented hearing impairment, more than in any other group (P < 0.

227 benefit to individuals in all categories of hearing impairment (normal, mild, moderate, severe, and

228 Autosomal recessive non-syndromal hearing impairment (NSRD) is genetically heterogeneous.

229 mbers, consistent with the optic atrophy and hearing impairment observed in human patients.

230 ho had confirmed bilateral OME and bilateral hearing impairment of 25-70 dB of at least 3 months' dur

231 Hearing impairment of at least mild severity was defined

232 mutation is responsible for the early onset hearing impairment of BUB/BnJ mice.

233 y, age-adjusted prevalence of high-frequency hearing impairment of mild or greater severity in the wo

234 adjusted prevalence of low- or mid-frequency hearing impairment of mild or greater severity in the wo

235 Children with bilateral permanent hearing impairment often have impaired language and spee

236 uditory hair cell defect is a major cause of hearing impairment, often leading to spiral ganglia neur

237 is of clinically diagnosed and self-reported hearing impairment on 723,266 individuals and identified

238 uditory brainstem responses indicated a mild hearing impairment on hair cell-specific deletion of all

239 The rate of hearing impairment or deafness was found to be 0% (0 of

240 Hearing impairment or vestibular dysfunction in humans o

241 85); deafness (OR, 2.19; 95% CI, 1.17-4.12); hearing impairment (OR,1.55; 95% CI, 1.29-1.87); upper e

242 tory factors such as neurological disorders, hearing impairment, or lack of adequate opportunity-are

243 56; hepatitis: OR 1.30; depression: OR 1.47; hearing impairment: OR 1.91) (all P < .05).

244 rt, IGF-1 was not associated with subsequent hearing impairment (OR5nmol/L increase; 95% CI: 1.01; 0.

245 ive protein levels, lower handgrip strength, hearing impairment, orthostatic hypotension, stroke, dia

246 They exhibited hearing impairment, otitis media, fusions of ossicles to

247 , personal or parental history of migration, hearing impairment, parental age, parental income, paren

248 ement for infants with a permanent childhood hearing impairment (PCHI) during 2011-2015 at a U.K. ser

249 born screening (UNS) for permanent childhood hearing impairment (PCHI) was undertaken to establish wh

250 Group [ECOG] performance status 2, renal or hearing impairment, peripheral neuropathy, aged at least

251 riants both segregated with the nonsyndromic-hearing-impairment phenotype within the three families,

252 ost common sensory disorder, with congenital hearing impairment present in approximately 1 in 1,000 n

253 This hearing impairment progressed with age.

254 The enrichment of hearing impairment-related genes in the SOC may have imp

255 e brain revealed a significant enrichment of hearing impairment-related oligos in the SOC (26 in the

256 ents surviving BTs were at elevated risk for hearing impairments (relative risk [RR], 17.3; P = <.000

257 ad an increased risk of exacerbations but no hearing impairment, resting tachycardia, or apparent ris

258 To study the mechanism of hearing impairment resulting from CABP2 loss of function

259 tive risk [RR], 1.62; 95% CI, 1.40-1.88) and hearing impairment (RR, 1.22; 95% CI, 1.04-1.44).

260 hose with missense mutations; development of hearing impairment showed a similar trend.

261 ver, cardiovascular grouping interacted with hearing impairment such that hyperglycemia in the contex

262 nt was independent of known risk factors for hearing impairment, such as noise exposure, ototoxic med

263 he acoustic startle response consistent with hearing impairment, suggesting a novel role for Rsph9 in

264 lying neurodegenerative disorder or isolated hearing impairment tended to hear more persistent music,

265 ently believed to be permanent, resulting in hearing impairment that affects more than 10% of the pop

266 air cell survival and therefore minimize the hearing impairment that normally occurs with aging and/o

267 with universal newborn screening and 57 had hearing impairment that was confirmed by nine months of

268 Tecta domains causing mid- or high-frequency hearing impairments that are either stable or progressiv

269 e been linked to the most frequent monogenic hearing impairment, the recessive isolated deafness DFNB

270 th a relative frequency greater than 4% were hearing impairment (three [3%] of 93 patients in the SRS

271 Symptoms such as hearing impairment, tinnitus, or a disturbance in sense

272 The data linking hearing impairment to incident late-life depression are

273 We locate the cause of the hearing impairment to the middle ear, demonstrating over

274 ew locus-DFNA17, for nonsyndromic hereditary hearing impairment-to chromosome 22q12.2-q13.3.

275 ent, mobility impairment, vision impairment, hearing impairment, urinary incontinence, and impairment

276 urance, participants with moderate or severe hearing impairment walked a mean distance of -2.81 m (95

277 The prevalence of hearing impairment was 1% (one of 96; 95% confidence int

278 Hearing impairment was assessed from the pure tone avera

279 In the Tobit regression model, severe hearing impairment was associated with a lower mean SPPB

280 n fully adjusted logistic regression models, hearing impairment was associated with higher odds of lo

281 Early detection of childhood hearing impairment was associated with higher scores for

282 Hearing impairment was associated with poorer performanc

283 Hearing impairment was common, particularly in the not o

284 Hearing impairment was defined as a pure-tone average of

285 Hearing impairment was evident after 4-8 weeks of ADR tr

286 Hearing impairment was first detected at 3 weeks of age,

287 The association between diabetes and hearing impairment was independent of known risk factors

288 Hearing impairment was more penetrant and stapes malform

289 Hearing impairment was more prevalent among adults with

290 hildren and 0.0% of controls (P < .001), and hearing impairment was observed in 2.1% of extremely pre

291 for low- or mid-frequency and high-frequency hearing impairment were 1.82 [CI, 1.27 to 2.60] and 2.16

292 r increase in birth year, the odds of having hearing impairment were 13% lower in men (odds ratio = 0

293 severe, sloping, symmetrical, sensorineural hearing impairment were fitted with hearing aids.

294 of the baseline scores paralleled degree of hearing impairment when impairment was defined using a b

295 t at 4 weeks most showed variable degrees of hearing impairment, which became severe or profound in a

296 Four subjects from three families reported hearing impairment, which has not previously been report

297 Atp6v1b1vtx/vtx mutant mice exhibit profound hearing impairment, which is associated with enlarged en

298 fferent types of gene products can result in hearing impairment, which, given the complexity of the a

299 This stop-gained mutation segregated with hearing impairment within the family and was not identif

300 Hearing impairment without threshold elevations can occu