ライフサイエンスコーパス: hearing loss

1 lood flow reduction, which may contribute to hearing loss.

2 althy diet might reduce the risk of acquired hearing loss.

3 mon disease in young children, can result in hearing loss.

4 articipants (n = 238) developed any level of hearing loss.

5 ists in caring for the adult population with hearing loss.

6 nelle connectomics may result in progressive hearing loss.

7 ition even in individuals with no measurable hearing loss.

8 disease-causing mechanism for DFNA10-related hearing loss.

9 arriers for delivery of therapeutics against hearing loss.

10 ing growth deficits, developmental delay and hearing loss.

11 strains with different levels of progressive hearing loss.

12 h rates (4 Hz) in listeners with age-related hearing loss.

13 eract with dementia pathology in people with hearing loss.

14 studying the mechanism underlying SV-related hearing loss.

15 ted by selective attention in listeners with hearing loss.

16 ncomplete penetrance as the reason for their hearing loss.

17 ccurring disease models to investigate human hearing loss.

18 relatively few adults receive treatment for hearing loss.

19 stem disorders, ranging from microcephaly to hearing loss.

20 correlation between hyperhomocysteinemia and hearing loss.

21 ective pexophagy as a cause of noise-induced hearing loss.

22 , one of its major side effects is permanent hearing loss.

23 as BACE1-deficient mice exhibit significant hearing loss.

24 erapy has potential to reverse some forms of hearing loss.

25 rategies to diagnose and treat sensorineural hearing loss.

26 ane interface binding activity, resulting in hearing loss.

27 ld shifts, synaptopathy and permanent hidden hearing loss.

28 limiting side effects including irreversible hearing loss.

29 of stereocilia, and they develop progressive hearing loss.

30 currently being investigated clinically for hearing loss.

31 ith acquired (age-related and noise-induced) hearing loss.

32 icated in both age-related and noise-induced hearing loss.

33 argets and novel therapies for noise-induced hearing loss.

34 ng and usually the first sign of age-related hearing loss.

35 w molecular pathways involved in progressive hearing loss.

36 essment techniques to study tumor growth and hearing loss.

37 = 30 mL/min), grade 2 neuropathy, or grade 2 hearing loss.

38 pact of genetics upon the risk of developing hearing loss.

39 rombocytopenia, photophobia, and progressive hearing loss.

40 tus indeed has different subtypes related to hearing loss.

41 s due to tinnitus from those that are due to hearing loss.

42 imental actions of caffeine and cisplatin on hearing loss.

43 in cochlea and potentiate cisplatin-induced hearing loss.

44 rt the use of PBM for aminoglycoside-induced hearing loss.

45 ntal retardation, seizures) to non-syndromic hearing loss.

46 dle ear may be able to reverse sensorineural hearing loss.

47 s exploring the role of DUSP1 in hearing and hearing loss.

48 ly between the two most common etiologies of hearing loss.

49 vity and give rise to late-onset progressive hearing loss.

50 cochlear function and the causes of cochlear hearing loss.

51 side ototoxicity, a common cause of acquired hearing loss.

52 ud music too often, results in noise-induced hearing loss.

53 be a viable strategy to prevent age-related hearing loss.

54 ders and in 5 out of 28 (~18%) children with hearing loss.

55 nerate over time, giving rise to progressive hearing loss.

56 in IHCs are a potential cause of age-related hearing loss.

57 "Growing old" is the most common cause of hearing loss.

58 t of inner ear disorders such as age-related hearing loss.

59 m albumin, body mass index, and pre-existing hearing loss.

60 have been linked to auditory dysfunction and hearing loss.

61 tributor to the hearing handicap in cochlear hearing loss.

62 o assess the degree and underlying source of hearing loss.

63 mptomatic at birth, but 10%-15% will develop hearing loss.

64 /ba/ are evaluated across various degrees of hearing loss.

65 ontributes to the progression of age-related hearing loss.

66 ce scores were associated with lower risk of hearing loss.

67 provides a primer on diagnosing and managing hearing loss.

68 rders following noise exposure or conductive hearing loss.

69 for recessively inherited moderate to severe hearing loss.

70 exposure is the largest preventable cause of hearing loss.

71 of a "phantom" sound that often accompanies hearing loss.

72 orns and children with metabolic diseases or hearing loss (106 participants total).

73 as DFNA5)-mutated in familial ageing-related hearing loss(2)-can be cleaved by caspase 3, thereby con

74 most frequent reason for request the MRI was hearing loss (52.5%).

75 family with autosomal dominant non-syndromic hearing loss (ADNSHL).

76 Hearing loss affects 380 million people worldwide due to

77 ed diagnosis, type, laterality and degree of hearing loss, age of onset, and additional variables suc

78 ory cortex (PAC) in patients with asymmetric hearing loss (AHL).

79 d contribute to the different progression of hearing loss among mouse strains.

80 op a clinical prediction model of AG-induced hearing loss among patients initiating DR-TB treatment i

81 redict which infants will have sensorineural hearing loss, among asymptomatic cCMV there are currentl

82 for public policies to prevent noise-induced hearing loss, an entirely avoidable hearing loss etiolog

83 rences in accuracy between older adults with hearing loss and a control group on the VSTMB task from

84 gata3 in inner hair cells causes progressive hearing loss and accounts for at least some of the deafn

85 hypermobility, hypotonia, hyperelastic skin, hearing loss and aortic rupture.

86 hair cells in the ear, causing irreversible hearing loss and balance deficits for millions.

87 One sibling had late onset hearing loss and both siblings had symmetric high myopia

88 arch and novel interventions for alleviating hearing loss and cognitive decline.

89 al interest lies in the relationship between hearing loss and cognitive impairment.

90 e new insights for future work in SV-related hearing loss and hearing fluctuation.

91 lso in predicting late-onset and progressive hearing loss and identifying individuals who are at risk

92 , we can develop strategies for ameliorating hearing loss and improving speech recognition technology

93 et to study treatment strategies for genetic hearing loss and inner ear development.

94 CMV) infection is a major cause of childhood hearing loss and neurodevelopmental delay.

95 virus (cCMV) infection is a leading cause of hearing loss and neurological disabilities in children,

96 er and bilateral non-syndromic sensorineural hearing loss and provide further data supporting a role

97 2, characterized by congenital sensorineural hearing loss and retinitis pigmentosa (RP), and also con

98 To determine the differential effect of hearing loss and tinnitus, both male and female particip

99 Early identification of hearing loss and understanding its etiology can assist w

100 s with non-syndromic bilateral sensorineural hearing loss and vestibular areflexia.

101 capacity, and their death leads to permanent hearing loss and vestibular dysfunction.

102 associated with high rates of post-operative hearing loss and vestibular dysfunction.

103 ions cause Usher's syndrome, associated with hearing loss and visual impairment.

104 f 24 months, the proportion of sensorineural hearing loss and/or neurologic sequelae were 32.4% (95%

105 27 males with a range of ages and degrees of hearing loss) and 27 young, normal-hearing listeners wit

106 n-dependent diabetes mellitus, sensorineural hearing loss, and mild intellectual disability.

107 After controlling for age, hearing loss, and stimulus variables, we discovered that

108 cated in pathophysiology including epilepsy, hearing loss, and the genetic disorders Andermann, Gitel

109 Hair cell death and consequent hearing loss are common results of treatment with ototox

110 with similar clinically defined severity of hearing loss are often assumed to reflect central neural

111 Age-related hearing loss (ARHL) (presbycusis) first affects the abil

112 Age-related hearing loss (ARHL) has been posited as a possible modif

113 Age-related hearing loss (ARHL) is a common problem for older adults

114 Age-related hearing loss (ARHL) is a threat to future human wellbein

115 Age-related hearing loss (ARHL) is a very heterogeneous disease, res

116 Age-related hearing loss (ARHL) is associated with the loss of inner

117 Presbycusis or age-related hearing loss (ARHL) is the most common sensory deficit i

118 Presbycusis, or age-related hearing loss (ARHL), is a major public health issue.

119 Epidemiological studies identify midlife hearing loss as an independent risk factor for dementia,

120 ts in ear canal development can cause severe hearing loss as sound waves fail to reach the middle ear

121 gene knock-out caused premature progressive hearing loss, as confirmed by auditory evoked responses

122 es increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia

123 ygous for del10 exhibit moderate-to-profound hearing loss at 4 weeks of age as measured by tone burst

124 The model predicting hearing loss at frequencies from 250 to 8000 Hz included

125 iagnosis of bilateral profound sensorineural hearing loss at neonatal hearing screening shortly after

126 = 0.81) but weaker for clinically determined hearing loss (AUC = 0.60).

127 s commonly identified in the pathogenesis of hearing loss based upon findings from excised tissue, th

128 transducer current, and develop progressive hearing loss, becoming deaf by 8 months of age.

129 downstream targets, where the pathologies of hearing loss begin.

130 tive GABA reuptake inhibitor during or after hearing loss, behavioral deficits were entirely correcte

131 as a viable therapeutic target not only for hearing loss but also other neurodegenerative diseases.

132 hearing problems in noise, known as "hidden hearing loss," but existing studies are controversial.

133 ring difficulties in noise, known as "hidden hearing loss," but support for this hypothesis is contro

134 e sensitized for detection of high-frequency hearing loss by low-pass filtering the broadband masking

135 proach to identify new molecules involved in hearing loss by screening a large cohort of newly genera

136 ird of individuals are affected by disabling hearing loss by the age of 65.

137 in hearing research: early-onset progressive hearing loss (C57BL/6J and C57BL/6NTac) and 'good hearin

138 ouse strains with a different progression of hearing loss (C57BL/6J, C57BL/6NTac, C57BL/6NTac(Cdh23+)

139 Hearing loss can be congenital, delayed onset, or acquir

140 cognitive deficits induced by developmental hearing loss can be prevented.SIGNIFICANCE STATEMENT Eve

141 Without hearing rehabilitation, hearing loss can cause detrimental effects on speech, la

142 is important, especially in children because hearing loss can impair speech-language acquisition deve

143 ATEMENT Even a temporary period of childhood hearing loss can induce communication deficits that pers

144 Transient periods of childhood hearing loss can induce deficits in aural communication

145 pes cavus, optic atrophy, and sensorineural hearing loss (CAPOS) syndrome is caused by the single mu

146 Hearing loss caused by the death of sensory hair cells o

147 Although recent studies indicate that hearing loss causes neuroinflammation in the auditory pa

148 Nhe6 knockout (KO) mice showed significant hearing loss compared to WT littermates.

149 Whereas traditional approaches distill hearing loss configurations down to a few canonical type

150 lar types, that only lacked the more extreme hearing loss configurations observed in our patient coho

151 Hearing loss correlated with cell death in hair cells, d

152 Second, EHF hearing loss correlated with self-reported difficulty he

153 without the observed functional compensation hearing loss could be greater.

154 Yet, it is unclear whether a peripheral hearing loss degrades the attentional modulation of cort

155 at it cannot explain why some people without hearing loss develop tinnitus, whereas conversely others

156 cteremic pneumonia, or bacteremia (including hearing loss, developmental delay, and speech delay, but

157 itution that causes the dominant progressive hearing loss, DFNA36.

158 minantly inherited progressive sensorineural hearing loss (DFNA41).

159 Gerbils reared with transient hearing loss displayed both learning and perceptual defi

160 lop tinnitus, whereas conversely others with hearing loss do not develop tinnitus.

161 ngs demonstrate that even a mild-to-moderate hearing loss during early-to-mid childhood can lead to c

162 ateral earplugs to induce a mild, reversible hearing loss during the critical period of auditory cort

163 TS), which is characterised by sensorineural hearing loss, dystonia and blindness.

164 rs of male chinchillas between two prevalent hearing loss etiologies: metabolic hearing loss (MHL) an

165 ced compared with an age-related (metabolic) hearing loss etiology may explain heightened speech perc

166 -induced hearing loss, an entirely avoidable hearing loss etiology, and for personalized strategies t

167 featuring varying degrees of high-frequency hearing loss, flat loss, mixed loss, and notched profile

168 cCMV and related sequelae (neurologic and/or hearing loss) following a maternal infection in the firs

169 mination was similar for ultrahigh-frequency hearing loss (frequencies >9000 Hz; AUC = 0.81) but weak

170 Elmod3-/- mice started to exhibit hearing loss from 2 months of age, and the deafness prog

171 date, as it contains our top SNP, is a known hearing loss gene, has been linked to age-related hearin

172 This was most prominent in the hearing loss group without tinnitus.

173 Recently, hearing loss has been identified as potentially the most

174 ency hearing loss (SFHL), and high frequency hearing loss (HFHL) in adolescent participants of the Na

175 functional properties lead to noise-induced hearing loss, highlighting the importance of these chann

176 progressive sensorineural autosomal dominant hearing loss (HL) in 20 affected individuals from the DF

177 tomegalovirus infection (cCMVI) to permanent hearing loss (HL) in highly seropositive populations is

178 Hearing loss (HL) is the most common neurodegenerative d

179 Hearing loss (HL) is the third most common chronic physi

180 million people worldwide are diagnosed with hearing loss (HL).

181 While commonly associated with hearing loss, hyperacusis can also occur without hearing

182 Disabling hearing loss impacts ~466 million individuals worldwide

183 ing loss, hyperacusis can also occur without hearing loss, implicating the central nervous system in

184 stigated the spectrum of genetic variants in hearing loss in a cohort of singleton affected individua

185 Consequences of hearing loss in children include worse outcomes in speec

186 Hearing loss in children is common and by age 18 years,

187 Hearing loss in children is common, and there has been s

188 ment, loss of Gsta4 results in more profound hearing loss in female mice compared to male mice.

189 When administered at nighttime, a mild hearing loss in GLAST KO mice was found but not at dayti

190 Furthermore, our work indicates that hearing loss in human hypoparathyroidism, deafness and r

191 ge to inner ear generally leads to permanent hearing loss in humans.

192 contributes to one third of all early-onset hearing loss in seropositive populations.

193 genes are responsible for moderate to severe hearing loss in sporadic individuals born to consanguine

194 hs of age, were correlated with the level of hearing loss in the different mouse strains, being most

195 ral olivocochlea fibres, was correlated with hearing loss in the different mouse strains.

196 al hearing in one ear and severe or profound hearing loss in the other.

197 Most (58%) of all hearing loss in the population was attributable to consa

198 NF2 (median age, 23 years) with progressive hearing loss in the target ear (median baseline WRS, 53%

199 Transient developmental hearing loss induced both learning and perceptual defici

200 to have a therapeutic effect on irreversible hearing loss induced by aminoglycosides, including genta

201 Here, we asked whether hearing loss-induced behavioral deficits could be revers

202 Similarly, SGRI prevented the hearing loss-induced reduction of GABA(A) and GABA(B) IP

203 ent during the critical period prevented the hearing loss-induced reduction of IPSP amplitudes; but w

204 al studies have suggested a relation between hearing loss-induced tonotopic reorganization and tinnit

205 spondylo-epiphyseal dysplasia, sensorineural hearing loss, intellectual disability and Leber congenit

206 Age-related hearing loss is a progressive hearing loss involving environmental and genetic factors

207 Hearing loss is a major risk factor for tinnitus, hypera

208 Age-related hearing loss is a progressive hearing loss involving env

209 Hearing loss is a significant late effect among childhoo

210 Inherited hearing loss is associated with gene mutations that resu

211 Hearing loss is associated with ~8100 mutations in 152 g

212 dividuals without previous family history of hearing loss is challenging and has been relatively unex

213 ctive personalized therapeutic treatment for hearing loss is currently not available.

214 ory of hearing loss, we estimate that 56% of hearing loss is genetic and 44% is not genetic.

215 Hearing loss is highly prevalent and may significantly a

216 Hearing loss is known to induce plastic changes in corti

217 Hearing loss is often due to the absence or the degenera

218 ng or preventing underlying genetic forms of hearing loss is poised to become a reality.

219 ution to the global prevalence of hereditary hearing loss is still widely unknown.

220 VSs) that cause progressive and debilitating hearing loss, leading to social isolation and increased

221 identification of the underlying etiology of hearing loss making development of pharmacological or mo

222 Hidden hearing loss manifests as speech perception difficulties

223 ors and studied multiplex family age-related hearing loss (mARHL) and simplex/sporadic age-related he

224 Hearing rehabilitation for children with hearing loss may include use of hearing aids, cochlear i

225 ear function and suggest that early forms of hearing loss may result from physiological changes in th

226 Early EHF hearing loss may thus be an easily measured, preventive

227 prevalent hearing loss etiologies: metabolic hearing loss (MHL) and noise-induced hearing loss (NIHL)

228 (C57BL/6J and C57BL/6NTac), from late-onset hearing loss mice (C3H/HeJ), and from mice corrected for

229 nal characteristics of IHCs from early-onset hearing loss mice harbouring the allele Cdh23(ahl) (C57B

230 he effects of mild-to-moderate sensorineural hearing loss (MMHL) during development.

231 Evaluation of hearing loss must be based on suspected diagnosis, type,

232 ic agent for solid tumors causes significant hearing loss, nephrotoxicity and peripheral neuropathy.

233 on the possible causal relationship between hearing loss, neural reorganisation, and cognitive impai

234 the auditory cortex following noise-induced hearing loss (NIHL) and its role in tinnitus in rodent m

235 Noise-induced hearing loss (NIHL) is a common health concern with sign

236 iometric notches indicative of noise-induced hearing loss (NIHL), speech frequency hearing loss (SFHL

237 tabolic hearing loss (MHL) and noise-induced hearing loss (NIHL).

238 d map reorganization are a characteristic of hearing loss, not of tinnitus.

239 l delay, brain dysmyelination, sensorineural hearing loss, nystagmus, progressive cholestatic liver d

240 Less education in early life, hypertension, hearing loss, obesity, and physical inactivity have part

241 Thirty-four loci are novel associations with hearing loss of any form, and only one of the ten known

242 gether, these data strongly suggest that the hearing loss of BACE1 knock-out mice represents a develo

243 TEMENT People with age-related sensorineural hearing loss often struggle to follow speech in the pres

244 an listeners to examine potential effects of hearing loss on EEG correlates of speech envelope synchr

245 e significantly reduced within a few days of hearing loss onset, and this reduction persisted into ad

246 livery, and there was no history of familial hearing loss or maternal illness.

247 .73), chronic kidney disease (P = 0.09), and hearing loss (P = 0.31).

248 at majority (87%) of families with inherited hearing loss, panel-based genomic DNA sequencing, follow

249 athophysiological progression of age-related hearing loss, possibly aimed at preserving functionality

250 der listeners with age-related sensorineural hearing loss (presbycusis) often struggle to understand

251 To better account for the full spectrum of hearing loss profiles, we used a Gaussian Mixture Model

252 n incomplete form of central compensation to hearing loss, rather than excessive adaptation.

253 In hearing loss-reared animals, cortical IPSP amplitudes we

254 is hindered by differences in definitions of hearing loss, recommendations for surveillance modalitie

255 tion of CR tones that accounts for f(T)- and hearing loss-related ERB widening and ERB overlaps and g

256 auditory pathway, the mechanisms underlying hearing loss-related pathologies are still poorly unders

257 development of therapeutic interventions for hearing loss requires fundamental knowledge about the si

258 ed the long-term incidence and predictors of hearing loss requiring hearing amplification devices (HA

259 Neural plasticity due to hearing loss results in tonotopic map changes.

260 ith a novel syndrome known as Short stature, Hearing loss, Retinitis pigmentosa and distinctive Facie

261 oss (mARHL) and simplex/sporadic age-related hearing loss (sARHL) cases and controls with normal hear

262 nduced hearing loss (NIHL), speech frequency hearing loss (SFHL), and high frequency hearing loss (HF

263 treatment for individuals with sensorineural hearing loss.SIGNIFICANCE STATEMENT Differences in speec

264 making it the leading cause of sensorineural hearing loss (SNHL) in childhood.

265 Sensorineural hearing loss (SNHL) is associated with intellectual and

266 Sensorineural hearing loss (SNHL) is the most common sensory disorder.

267 se exposure, a common cause of sensorineural hearing loss (SNHL), leads to cognitive impairments in m

268 detection in individuals with sensorineural hearing loss (SNHL).

269 compared with those caused by sensorineural hearing loss (SNHL).

270 xposures and late effects of cardiomyopathy, hearing loss, stroke, thyroid disorders, and diabetes we

271 c and environmental factors that can lead to hearing loss that is congenital or late onset, stable or

272 egeneration is a common trait of age-related hearing loss, the objective of this study was to investi

273 ing a cutoff of 80% predicted probability of hearing loss, the positive predictive value of this mode

274 he auditory midbrain of gerbils with "hidden hearing loss" through noise exposure that increased hear

275 We characterized the genetics of hearing loss throughout the Palestinian population, enro

276 as intended to clarify the relations between hearing loss, tinnitus, and tonotopic reorganization.

277 both have an increased risk of ototoxicity (hearing loss, tinnitus, or both).

278 People suffering from age-related hearing loss typically present with deficits in temporal

279 s that predict the presence of sensorineural hearing loss using only miRNA expression profiles.

280 Hearing loss was associated with a weaker capacity to pr

281 Hearing loss was associated with increased cochlear inju

282 The outcome of AG-induced hearing loss was identified from audiometric and clinica

283 Genetic heterogeneity of hearing loss was striking with respect to both genes and

284 e of dynamic stability prior to the eventual hearing loss we discovered a set of evolutionarily conse

285 In a human study tightly controlled for hearing loss, we establish a tinnitus subtype associated

286 alestinian families with no prior history of hearing loss, we estimate that 56% of hearing loss is ge

287 ng polyserositis, myalgia, epididymitis, and hearing loss weeks to months after recovery from acute i

288 12 months, but VL breakpoints predictive of hearing loss were not identified.

289 cognitive deficits induced by developmental hearing loss were prevented with a treatment that rescue

290 enty-one individuals with moderate to severe hearing loss were recruited.

291 This is particularly true for sensorineural hearing loss, which contributes to one third of all earl

292 ecline in consanguineous marriage, inherited hearing loss will likely be much rarer in the next gener

293 BL/6 background which develop high frequency hearing loss with age making them a less optimal choice

294 l disability, psychomotor development delay, hearing loss with disyllable pronunciation only, hyperac

295 e participants with bilateral high-frequency hearing loss, with and without tinnitus, and a control g

296 on of caffeine exacerbates cisplatin-induced hearing loss without increasing the damage to outer hair

297 Similarly, the tonotopic maps for the hearing loss without tinnitus group were significantly d

298 ants appear intermediate to the controls and hearing loss without tinnitus group.

299 conservative form of reorganization than in hearing loss without tinnitus.

300 -limited settings often experience permanent hearing loss, yet there is no practical method to identi