ライフサイエンスコーパス: heat shock

1 ss and promotes cell cycle reentry following heat shock.

2 Hsp70 (Ssa1) is differentially modified upon heat shock.

3 vironment abolished the protective effect of heat shock.

4 e penetrance of mutations and lifespan after heat shock.

5 nd K562 that are deacetylated in response to heat shock.

6 ators and maintenance of the epigenome after heat shock.

7 transcripts that overexpress in response to heat shock.

8 visiae in response to glucose starvation and heat shock.

9 rately predicts PrLD assembly into foci upon heat shock.

10 1 phenocopy PI(3)P-deficient parasites under heat shock.

11 ructs of human alphaB-crystallin (HSPB5) and heat-shock 27-kDa protein (Hsp27, HSPB1) during amyloid

12 acrine signaling that requires extracellular heat shock 70-kDa protein (HSP70).

13 ate valosin-containing protein/p97 (VCP) and heat shock 70-kDa protein 8 (HSPA8).

14 ces cyclin D1 expression by interacting with heat shock 71 kDa protein 8 (HSC70).

15 monocytes, monocyte-derived macrophages, and heat shock-activated monocytes.

16 Heat shock also induces LATS ubiquitination and degradat

17 bpopulation adopts chaperone function during heat shock, an activity that facilitates the transition

18 nduction of early response genes, oxidative, heat shock and endoplasmic reticulum stress, DNA damage

19 es cellular adaptation to challenges such as heat shock and oxidative and proteotoxic stresses.

20 downregulation hypersensitizes parasites to heat shock and PI3K inhibitors.

21 We derive a core gene set of 512 heat shock and stress response genes, including FOS and

22 Thus, orthologous hypoxia, heat-shock, and circadian clock proteins were found to c

23 ly unknown mechanisms of Hippo regulation by heat shock, as well as physiological functions of YAP, i

24 obtained using our platform with data from a heat shock-based transformation protocol and with data f

25 hat maize HEAT SHOCK FACTOR A2 (ZmHSFA2) and HEAT SHOCK BINDING PROTEIN 2 (ZmHSBP2) physically intera

26 of E. coli proliferation was exacerbated by heat shock but was nearly eliminated in a ClpB-deficient

27 ce showed significantly altered responses to heat shock challenge.

28 d DO was associated with up-regulation of 24 heat shock chaperones involved in protein folding and wi

29 ures of long-term balancing selection in the heat-shock co-chaperone sacsin We conducted a genome-wid

30 ntitative identification of HSP70 and 71 kDa heat shock cognate (HSC70) clients using a ubiquitin-med

31 Selectivity lies in the chaperone heat shock cognate 71 kDa protein (HSC70) recognizing a

32 e, 14-3-3 protein zeta/delta, cofilin-1, and heat shock cognate 71 kDa protein as novel biomarkers fo

33 e, 14-3-3 protein zeta/delta, cofilin-1, and heat shock cognate 71 kDa protein into a multimarker pre

34 ns as part of a foldosome complex containing heat shock cognate 71-kDa protein (HSC70) and the HSC70/

35 DjA1 is a cochaperone of Heat shock cognate 71-kDa protein (Hsc70), but the activ

36 HSCB (heat shock cognate B), which encodes a mitochondrial coc

37 ochondrial cochaperone, also known as HSC20 (heat shock cognate protein 20), is the partner of mitoch

38 Here, we show that heat shock cognate protein 70 (HSC70) complexes with NLR

39 ath-mediated protein release, but depends on heat-shock cognate protein 70 (HSC70) and its KFERQ-like

40 In animal models, induction of heat shock confers substantial otoprotection against ami

41 tor heat shock factor 1 (HSF-1), which binds heat shock elements (HSEs) in the promoters of genes ind

42 k, HSF-1 binds well-conserved motifs, called Heat Shock Elements (HSEs), and drives expression of gen

43 hock Factor 1 (HSF1) that activates HSR, and heat shock elements (HSEs), the binding sites for HSF1 -

44 ence of introns within genes and presence of heat shock elements in their promoter areas, the present

45 tem, which can also be temporally induced by heat shock, enables the temporal resolution of lineage d

46 distinct environmental stressors, including heat shock, endoplasmic reticulum stress, and arsenic.

47 cclimated adults) or subjected to a separate heat shock experiment were able to activate the full HSR

48 Heat Shock Factor 1 (HSF-1) is a key regulator of the he

49 vation of the conserved transcription factor heat shock factor 1 (HSF-1), which binds heat shock elem

50 cells whereby the transcriptional regulator Heat Shock Factor 1 (HSF1) drives a transcriptional prog

51 nserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells.

52 ucial role for the transcriptional regulator heat shock factor 1 (HSF1) in orchestrating these events

53 nstrated in vitro that active RhoC increased heat shock factor 1 (HSF1) phosphorylation, which induce

54 heat shock, or proteotoxic stress, response, heat shock factor 1 (HSF1) preserves proteomic stability

55 Heat shock factor 1 (HSF1) regulates cellular adaptation

56 al integrity of two crucial HSR regulators - Heat Shock Factor 1 (HSF1) that activates HSR, and heat

57 olecular chaperones that interact with human Heat Shock Factor 1 (HSF1), and observed an increased as

58 Knockdown of Heat Shock Factor 1 (HSF1), the master transcriptional r

59 eversal observed in model systems involves a heat shock factor 1 (HSF1)-mediated stress pathway.

60 infection of macrophages and suppression of heat shock factor 1, a transcriptional regulator of MDR1

61 We report here that maize HEAT SHOCK FACTOR A2 (ZmHSFA2) and HEAT SHOCK BINDING PR

62 CK FACTOR TRANSCRIPTION FACTOR13 (HSFTF13, a HEAT SHOCK FACTOR A6B [HSFA6B] family member) was compro

63 The expression of a key HEAT SHOCK FACTOR TRANSCRIPTION FACTOR13 (HSFTF13, a HEA

64 for cis-elements of ethylene-responsive and heat shock factor transcription factors, respectively.

65 rt that condensation and phase transition of heat-shock factor 1 (HSF1), a transcriptional regulator

66 -response element-binding protein (CREB) and heat-shock factor-4a (HSF-4a) facilitated the ANG II-med

67 stress (HS) by activating the expression of heat shock family proteins (HSPs) and other antioxidants

68 Although the response of canonical heat-shock genes dominates expression across cell types,

69 We previously found that the heat-shock GTPase HflX in the human pathogen Staphylococ

70 Heat shock has long been known to cause transient intrac

71 transcriptional activation occurring during heat shock (HS) induction is associated with the generat

72 Heat shock (HS) initiates rapid, extensive, and evolutio

73 research aimed to understand the effect of a heat shock (HS) prior to controlled atmosphere (CA) stor

74 and C-terminal domain occurs in response to heat shock (HS), allowing PARP-1 to scan chromatin for s

75 endogenous Hsp70 genes turn on 2-4 min after heat shock (HS), irrespective of their distance to speck

76 (HSEs) in the promoters of genes induced by heat shock (HS).

77 otein (PcG) complex integrity in response to heat shock (HS).

78 Upon heat shock, HSF-1 binds well-conserved motifs, called He

79 During heat shock, Hsp70 is out-titrated by misfolded proteins

80 onal and physiological responses to a sudden heat shock in Arabidopsis are profoundly sensitive to th

81 t-1/p62 is required for hormetic benefits of heat shock, including longevity, improved neuronal prote

82 eased association with several proteins upon heat shock, including translation elongation factors and

83 Heat shock induced progressive loss of 5' RNA binding by

84 at these residues alter expression of other heat-shock induced chaperones as well as directly influe

85 Similarly, half of heat shock-induced gene loci already preposition very cl

86 A Pol II is rapidly released from pausing at heat shock-induced genes, while most genes are paused an

87 a forward genetic screen for suppressors of heat-shock-induced gene expression in Caenorhabditis ele

88 l-2 provides insights into the regulation of heat-shock-induced gene expression to protect against he

89 strated that affl-2 mutants are deficient in heat-shock-induced transcription.

90 Heat shock induces a conserved transcriptional program r

91 Heat shock-inducible Cas9 was used for generating target

92 Notably, heat shock induction of ycjX exceeded even levels observ

93 Heat shock inhibits LATS kinase by promoting HSP90-depen

94 Conversely, sudden and acute heat shock leads to a stronger, coordinated response and

95 We, therefore, hypothesized that, heat shock may also be especially toxic to myeloma cells

96 ned the response of the siw14Delta mutant to heat shock, nutrient limitation, osmotic stress, and oxi

97 The effect of heat shock on YAP is dominant to other signals known to

98 Upon exposure to cellular stresses, such as heat shock or acidosis, HSP27 oligomers can dissociate i

99 fied interacting proteins in the response to heat shock or in the presence of a poly-glutamine aggreg

100 oth increase in proteotoxic conditions (e.g. heat shock or proteasome inhibition).

101 onal control of the evolutionarily conserved heat shock, or proteotoxic stress, response, heat shock

102 eat shock protein 70 (Hsp70) and cochaperone heat shock organizing protein (HOP).

103 However, B2 expression from the constitutive heat shock promoter had no impact on baculovirus replica

104 pti dicer-2 (Aedicer-2) using a constitutive heat shock promoter.

105 information on heat-shock proteins (Hsp) and heat-shock promoters from an important agricultural inse

106 The heat-inducible activity of heat-shock promoters from several SfHsp genes was tested

107 Here, we show that the heat-shock protease FtsH is generally required for growt

108 wth and overlaps functionally with the other heat-shock protease-encoding genes hslVU, lon, and clpXP

109 Systematic deletion of the heat-shock protease-encoding genes reveals that the prot

110 The molecular chaperone heat shock protein (HSP) 101 is a protein disaggregase t

111 Heat shock protein (Hsp) 104 is a hexameric ATPases asso

112 Heat shock protein (Hsp) 70 modulators are being develop

113 We investigated a role for heat shock protein (hsp) 90 in Mb maturation in C2C12 sk

114 ntributing to PIC assembly and expression of Heat Shock Protein (HSP) genes.

115 conditions screened, combined inhibition of heat shock protein (Hsp)-90 and MEK was found to produce

116 d to the erythrocyte; among them is a single heat shock protein (Hsp)70-class protein chaperone, P. f

117 ly on nonhistone substrates such as tubulin, heat shock protein (HSP)90, Foxp3, and cortactin, to nam

118 The 70 kDa heat shock protein (HSP70) family of chaperones are the

119 Small-molecule inhibitors for the 90-kDa heat shock protein (HSP90) have been extensively exploit

120 tion is necessary for the phosphorylation of heat shock protein (HSP90) that binds to unliganded AR i

121 zed groups of client proteins for the 90-kDa heat shock protein (HSP90), a molecular chaperone that s

122 the chemistry of probes for the biomarkers, heat shock protein 10 and lysophosphatidic acid.

123 Heat Shock Protein 101 (HSP101), the homolog of Caseinol

124 n particular class B J-domain proteins and a heat shock protein 110 (Hsp110)-type nucleotide exchange

125 orskolin (FSK) as well as the induction of p-heat shock protein 20 after 4 h of stimulation with ISO

126 n early dissemination is mediated by MK2 and heat shock protein 27 (Hsp27).

127 and expression of the downstream MK2 target, heat shock protein 27 (HSP27); and markers of epithelial

128 Heat shock protein 47 (HSP47) is an endoplasmic reticulu

129 The human mitochondrial heat shock protein 60 (hsp60) is a tetradecameric chaper

130 ccupying the surface presented LAP receptor, heat shock protein 60 and ameliorates the Lm-induced int

131 n protein (LAP) with the host cell receptor (heat shock protein 60) disrupts the epithelial barrier,

132 this study, we found that the GroEL protein (heat shock protein 60) of Mycoplasma gallisepticum could

133 ssion of glial fibrillary acidic protein and heat shock protein 60.

134 Heat shock protein 70 (HSP70) acts in concert with sever

135 e critical to the protein-folding machinery: heat shock protein 70 (Hsp70) and cochaperone heat shock

136 Heat shock protein 70 (HSP70) chaperones play a central

137 The ER heat shock protein 70 (Hsp70) family member BiP is an AT

138 aperones, such as those that are part of the heat shock protein 70 (Hsp70) family of proteins that bi

139 he potential role of the molecular chaperone heat shock protein 70 (HSP70) in prion replication in vi

140 inner ear tissue released exosomes carrying heat shock protein 70 (HSP70) in response to heat stress

141 Heat shock protein 70 (Hsp70) is an important molecular

142 urface plasmon resonance (SPR) biosensor and heat shock protein 70 (Hsp70) that recognizes and traps

143 relies on a multiprotein complex formed with heat shock protein 70 (Hsp70).

144 this fusion enzyme is the ability to recruit heat shock protein 70 (Hsp70).

145 ation after pre-fusion the HyT degrader with heat shock protein 70 (HSP70).

146 ochondrial membrane 34 (TOMM34) orchestrates heat shock protein 70 (HSP70)/HSP90-mediated transport o

147 The heat shock protein 70 (Hsp70):c-terminus of Hsp70-intera

148 Here, we identified Leishmania donovani heat shock protein 78 (LdHSP78), a putative caseinolytic

149 , we demonstrate that Mettl21c trimethylates heat shock protein 8 (Hspa8) at Lys-561 to enhance its s

150 on to the nucleus to identify a link between heat shock protein 90 (HSP90) and protein kinase A (PKA)

151 ach identified geldanamycin, an inhibitor of heat shock protein 90 (HSP90) as a candidate therapeutic

152 sGC (sGCbeta) is critical for function, and heat shock protein 90 (HSP90) associates with heme-free

153 Heat shock protein 90 (HSP90) binds to the N-terminal re

154 s, previously isolated from ICC samples, are heat shock protein 90 (HSP90) clients and undergo rapid

155 Cumulative evidence suggests that the heat shock protein 90 (Hsp90) co-chaperone UNC-45 myosin

156 Leveraging the unique surface expression of heat shock protein 90 (Hsp90) in breast cancer provides

157 rticipate in communicating with LGG and that heat shock protein 90 (HSP90) in these vesicles might me

158 Heat shock protein 90 (Hsp90) is a eukaryotic chaperone

159 Heat shock protein 90 (Hsp90) is a highly conserved mole

160 Heat shock protein 90 (Hsp90) is a molecular chaperone t

161 Heat shock protein 90 (Hsp90) is an evolutionarily conse

162 function of the dimeric molecular chaperone heat shock protein 90 (Hsp90), including transient, ATP-

163 er promoted T lymphocyte trafficking through heat shock protein 90 (Hsp90)-induced alpha4 integrin ac

164 1 from the TRIM23 complex that also contains heat shock protein 90 (Hsp90).

165 rough a proteomics screen, we identified the heat shock protein 90 B (hsp90B) chaperone as a direct M

166 Ganetespib, a highly potent heat shock protein 90 inhibitor, blocks multiple oncogen

167 ng cascade was mediated downstream by Hsp90 (heat shock protein 90), which in turn modulated mitochon

168 mplex that includes at least HYL1, AGO1, and HEAT SHOCK PROTEIN 90.

169 ctor receptor, cyclin-dependent kinases, and heat shock protein 90.

170 he impact of phosphosites in the L. donovani heat shock protein 90.

171 1 (HSF1) phosphorylation, which induced the heat shock protein 90alpha (HSP90alpha) expression, lead

172 protein 20), is the partner of mitochondrial heat shock protein A9 (HSPA9).

173 The small heat shock protein alphaA-crystallin is a molecular chap

174 s of BAG3-interacting proteins, such as p62, heat shock protein B8, and alphaB-crystallin.

175 When the J-domain of the heat shock protein DnaJB1 is fused to the catalytic (C)

176 is characterized by in-frame fusion of DnaJ heat shock protein family (Hsp40) member B1 (DNAJB1) wit

177 A human molecular chaperone protein, DnaJ heat shock protein family (Hsp40) member B6 (DNAJB6), ef

178 Mortalin [also known as heat shock protein family A (HSP70) member 9 (HSPA9) or

179 vented the normal upregulation of a group of heat shock protein genes in response to elevated tempera

180 dosage-sensitive proteins such as the small heat shock protein Hsp20, which exists in a dodecameric

181 rtial unfolding of its structure convert the heat shock protein Hsp33 into a highly active chaperone

182 We provide evidence that the heat shock protein HSP90 enhances wound responses at ET

183 rexpressed in metastatic PCs, TRPM8, and the heat shock protein HSPB8, whose levels were significantl

184 pha), the transcription factor ATF4, and the heat shock protein HSPB8.

185 w that in Mycobacterium smegmatis, the small heat shock protein HspX plays a critical role in the pol

186 plementary target-engagement method, HIPStA (Heat Shock Protein Inhibition Protein Stability Assay),

187 proteins, and the recruitment of a cellular heat shock protein, Hsc70, to nuclear domains.

188 UIMs function by interacting with the heat shock protein, Hsc70-4, whose reduction diminishes

189 is mellifera) and expression of a ubiquitous heat shock protein, HSP70, in their central nervous syst

190 Extracellular heat shock protein-90alpha (eHsp90alpha) plays an essent

191 obable trehalose-phosphate phosphatase 2 and heat shock protein.

192 The molecular chaperone 90-kDa heat-shock protein (Hsp90) assists the late-stage foldin

193 heavy chain-binding protein (BiP) homologue Heat-Shock Protein 4 (HSP-4), is selectively induced in

194 ceraldehyde-3-phosate dehydrogenase (G3PDH), heat-shock protein 60 (HSP60), DNA-dependent RNA polymer

195 treatment, and this effect was dependent on heat-shock protein 86 (HSP86) as HSP86-deficient Ret cel

196 ging human brain that may be reversible with heat-shock protein 90 (Hsp90) inhibitors.

197 r), GSK-690693 (AKT inhibitor), and KW-2478 (heat-shock protein 90 inhibitor) were substrates.

198 DNAJC7 encodes a member of the heat-shock protein family, HSP40, which, along with HSP7

199 ated with differential upregulation of three heat-shock protein genes, allowed aphids to occupy highe

200 The small heat-shock protein HSP27 is a redox-sensitive molecular

201 STIP1 is a co-chaperone for the heat-shock protein, HSP90, and has been shown to have di

202 Heat shock proteins (Hsp) are a class of stress-inducibl

203 protective enzymes (NQO1, HO-1, AKR1C1), and heat shock proteins (HSP27 and HSP70), increased.

204 e under conditions that induce expression of heat shock proteins (Hsp; thought to be immune adjuvants

205 Heat shock proteins (HSPs) are a large group of chaperon

206 Heat shock proteins (Hsps) are highly conserved molecula

207 Induction of heat shock proteins (HSPs) confers protection against am

208 Induction of heat shock proteins (HSPs) in response to heat stress (H

209 ria synthesize a family of proteins known as heat shock proteins (HSPs) to facilitate adaptation and

210 Heat shock proteins (HSPs), through regulation of extrac

211 Small heat shock proteins (sHSPs) are a class of ATP-independe

212 Small heat shock proteins (sHsps) are a family of ubiquitous i

213 Small heat shock proteins (sHsps) are a ubiquitous and ancient

214 Small heat shock proteins (sHSPs) are an ubiquitous protein fa

215 Small heat shock proteins (sHsps) are conserved, ubiquitous me

216 Small heat shock proteins (sHSPs) are nature's 'first responde

217 Small heat shock proteins (sHsps) constitute a diverse chapero

218 Small heat shock proteins (sHSPs) delay protein aggregation in

219 inducing those of the ATP-independent small heat shock proteins (sHSPs).

220 ess response, measured via the production of heat shock proteins (the heat shock response (HSR)), was

221 Heat shock proteins 90 (Hsp90) and 70 (Hsp70) are two fa

222 tion of protein-coding genes (PCGs), such as heat shock proteins and cytoskeletal regulators, is crit

223 DnaK, homologs of the respective eukaryotic heat shock proteins Hsp104 and Hsp70, are essential in t

224 es the interaction between p53 and the small heat shock proteins HSP27 (also known as HSPB1) and alph

225 The core chaperones, such as the heat shock proteins Hsp60, Hsp70, and Hsp90, are widely

226 ted athanogene 3 (BAG3) is a co-chaperone to heat shock proteins important in degrading misfolded pro

227 results in the selective induction of small heat shock proteins in adulthood, thereby protecting aga

228 expression and cell surface localization of heat shock proteins in murine breast (4T1) and prostate

229 Heat shock proteins of 70 kDa (Hsp70s) are ubiquitous an

230 the mammalian stage of Leishmania parasites, heat shock proteins show increased phosphorylation, indi

231 eins known to underlie thermal stress (i.e., heat shock proteins) even at low temperatures that refle

232 ve glycation, including translation factors, heat shock proteins, and histones.

233 nt, including exhaustion of cardioprotective heat shock proteins, disruption of cytoskeletal proteins

234 e responses during ciliate exposure, such as heat shock proteins, glutathione metabolism, and the rea

235 ncreased abundance of proteins classified as heat shock proteins, intracellular traffic, disease/defe

236 EVs with neuroprotective molecules including heat shock proteins, synapsin 1, unique microRNAs, and g

237 The functional information on heat-shock proteins (Hsp) and heat-shock promoters from

238 ion: an expanded repertoire of 70 kilodalton heat-shock proteins (Hsp70) and avrRpt2 induced gene 1 (

239 ating transcription factors (e.g., Atf4) and heat-shock proteins (Hsps).

240 Small heat-shock proteins (sHSPs) are molecular chaperones tha

241 Small heat-shock proteins (sHsps) are molecular chaperones tha

242 Small heat-shock proteins (sHSPs) are ubiquitously expressed m

243 Small heat-shock proteins (sHsps) compose the most widespread

244 lines, even though the myeloma cells induced heat-shock proteins and increased protein degradation si

245 ing to four major insect Hsp families (small heat-shock proteins, Hsp60, Hsp70, and Hsp90) in S. frug

246 n significant reduction in the expression of heat-shock proteins, previously implicated in Tau proteo

247 This post-heat shock recovery of pan-nuclear CBX protein localizat

248 decreased capacity to mount responses by the heat shock response (HSR) and other proteostatic network

249 The unfolded protein response (UPR) and the heat shock response (HSR) are two evolutionarily conserv

250 The heat shock response (HSR) in the cytosol and nucleus, as

251 Elevated temperatures activate a heat shock response (HSR) to protect cells from the path

252 a the production of heat shock proteins (the heat shock response (HSR)), was separately evaluated.

253 ergone an evolutionary loss of the inducible heat shock response (HSR), while facing perpetual low-te

254 k Factor 1 (HSF-1) is a key regulator of the heat shock response (HSR).

255 cose concentration increased proteins of the heat shock response - indicating activation of the unfol

256 nmental pollutant demonstrated to induce the heat shock response and recruit protein chaperones to si

257 cellular Hsp90, which results in a prolonged heat shock response despite concomitant degradation of t

258 icated that pharmacological induction of the heat shock response in cells chronically infected with p

259 ion in the transcriptional activation of the heat shock response in stressed senescent cells.

260 monstrate that acidification is required for heat shock response induction in translationally inhibit

261 Failure of the heat shock response is a key event that leads to insulin

262 Activation of this heat shock response is triggered by heat-induced misfold

263 heat shock transcriptional response, but the heat shock response pathway is not yet fully understood.

264 Both of these aspects of the heat shock response remain intact upon NELF loss.

265 s lacking Mgat4d generally mounted a similar heat shock response to control germ cells, but could not

266 anonical role as the master regulator of the heat shock response, leading to enhanced expression of a

267 During the heat shock response, RNA Pol II is rapidly released from

268 ation of AFFL-2 is necessary for its role in heat shock response.

269 rop in intracellular pH helps to trigger the heat shock response.

270 ive dimension of the well-studied eukaryotic heat shock response.

271 BMD monocytes exhibited an altered in vitro heat shock response.

272 oraphane: redox metabolism/oxidative stress; heat shock response; and immune dysregulation/inflammati

273 he genome-wide effects of time-of-day on the heat-shock response and the effects of "diurnal bias" in

274 an HSF-1-dependent manner, and restores the heat-shock response in the somatic tissues of the parent

275 arrest, and that coordinated activity of the heat-shock response is required to ensure ongoing protei

276 this site (S151D) dramatically downregulate heat shock responses, a result conserved with HSC70 S153

277 YAP and TAZ are crucial for cellular heat shock responses, including the heat shock transcrip

278 the immunosuppressive phenotype and altered heat shock responses.

279 pattern in monocytes and altered immune and heat shock responsiveness after 30 days.

280 of fibroblasts from affected individuals to heat shock resulted in a marked delay in their stress re

281 of MAV preparations made with or without the heat shock step showed no clear differences in protein a

282 Previous studies have shown that heat shock stress may activate transposable elements (TE

283 ng arrays of the (AATGG)n repeat involved in heat shock stress response.

284 Gle1 is regulated by phosphorylation during heat shock stress.

285 evels of sqst-1/p62 increase upon a hormetic heat shock, suggesting a role of SQST-1/p62 in stress re

286 cretion; monocytes were also challenged with heat shock to quantify mRNA expression.

287 model system, we targeted the gene encoding Heat Shock Transcription Factor 1 (HSF1) and obtained la

288 Heat shock transcription factor 1 (HSF1) orchestrates ce

289 The heat shock transcription factor 1 (HSF1) protects cells

290 s animals by restricting the activity of the heat shock transcription factor HSF-1.

291 Furthermore, we demonstrated that the heat shock transcription factor HSFA6a directly binds th

292 treatment with small-molecule regulators of heat-shock transcription factor 1 (HSF1) proteostasis th

293 Age-related loss of the heat-shock transcription factor, HSF-1, disrupts the JUN

294 aryotes, HSF1 is the master regulator of the heat shock transcriptional response, but the heat shock

295 cellular heat shock responses, including the heat shock transcriptome and cell viability.

296 ates, but higher expression of B2, following heat shock treatment, inhibited dicer activity in all ce

297 (6)A-mediated mechanism is also at play upon heat shock treatment.

298 oX2 lncRNA using this approach revealed that heat shock, unlike the unfolded protein response, leads

299 Isolated exosomes from heat-shocked utricles were sufficient to improve surviva

300 oper HSF-1 expression and localization after heat shock, which suggests that affl-2 may function down