ライフサイエンスコーパス: heavily

1 al pathology, tooth loss) were weighted more heavily.

2 ry minor damage to enamel but are themselves heavily abraded (worn) in the process.

3 Interestingly, ERK was heavily activated in both patients, highlighting a poten

4 neutron scattering (SANS), have already been heavily adopted by the scientific community for use in t

5 to RVF virus (RVFV) in livestock in an area heavily affected by that outbreak.

6 France has been heavily affected by the severe acute respiratory syndrom

7 counties that will probably be consistently, heavily affected relative to the rest of the country acr

8 dary conditions selected for his model (e.g. heavily anaesthetized animals, negligible intramyocyte O

9 d soil erosion on river transport of Hg in a heavily ASGM-impacted watershed.

10 time, Pol II on alpha genes accumulated most heavily at promoter-proximal pause (PPP) sites located ~

11 ls, the TCR repertoire of reservoir cells is heavily biased: expanded clonotypes are present in all i

12 ulating additional methanogenesis in already heavily biodegraded oil reservoirs, oil sands samples we

13 A heavily boron-doped silicon substrate silences the photo

14 i screening indicates that only LCR segments heavily bound by this ternary complex are essential for

15 SDFs of the samples were composed of heavily branched heteromannans (~60%), slightly branched

16 nd higher proportion of hairy region that is heavily branched with arabinan and galactan side chains.

17 We identify 20 heavily burdened countries that account for over 75% of

18 nsformation with chromosomal DNA mutagenized heavily by in vitro transposition.

19 e cells are embedded within a matrix that is heavily calcified on the nanoscale.

20 pressure, with plants being more cryptic in heavily collected populations.

21 The burden of malaria is heavily concentrated in sub-Saharan Africa (SSA) where c

22 autocorrelated noise in FSL and SPM leads to heavily confounded first level results, particularly for

23 population falls within a m/z range already heavily congested with monoanions from more abundant gly

24 functional forms and, ultimately, to be more heavily constrained by survival optimality.

25 accident, and is still being detected in the heavily contaminated catchments of the Chernobyl Exclusi

26 llected off the coasts of Asia were the most heavily contaminated, coinciding with reported trends of

27 Microbial resting stages might heavily contribute to microbial biomass and thus drive t

28 e data suggest that repeated engagement with heavily cued probabilistic reward schedules can drive ad

29 tion of transition metals (TMs) in fresh and heavily cycled electrodes.

30 y photon irradiations, neutrons produce more heavily-damaged lymphocytes with multiple micronuclei/bi

31 A history of open-heart surgery has been a heavily debated topic in transvenous lead extraction.

32 the fossils, terrace fill and ages have been heavily debated(9-14).

33 resistance and disease progression has been heavily debated.

34 urs along the sides of fibrils, which become heavily decorated under the current solution conditions

35 ments from CBD reveal that this conformer is heavily decorated with posttranslational modifications (

36 Many Caribbean coral reefs are heavily degraded, yet their pre-human, natural states ar

37 t 1-X has an open core with the spin density heavily delocalized in the Co(IV)-O unit.

38 exacerbates inequality, especially when some heavily depend on collective action while others do not.

39 ct on private radiology practices, which are heavily dependent on examination volumes for practice re

40 who-already vulnerable and marginalized-are heavily dependent on face-to-face health care delivery.

41 sm behind the observed health effects and is heavily dependent on PM composition.

42 t charge capability of electric vehicles are heavily dependent on the 3D microstructure of lithium-io

43 However, their detection is still heavily dependent upon conventional biochemical assays t

44 bility and accuracy of this method, however, heavily depends on the quality of the acquired data, and

45 n-day and near-term hardening because of the heavily developed aspect of some shoreline segments.

46 onal orientation dispersion are eliminated - heavily diffusion-weighted MRI signals become sensitive

47 Typically, these inhibitory buffers are heavily diluted by the reaction mix (e.g., 10x dilution

48 H(3) NH(3) (+) is intrinsically polar, it is heavily disordered and this cannot be the sole reason fo

49 arthropod feeding groups and was similar for heavily disturbed versus relatively natural sites.

50 For heavily doped samples, the phonon spectrum is further mo

51 This uncovered several that were heavily enriched in development but reduced in adulthood

52 xoG RIP-seq) to identify 343 RNA transcripts heavily enriched in oxidations in human bronchial epithe

53 It is now extinct, having been heavily exploited for its eggs, meat, and feathers.

54 e not rare, occurring most often at shallow, heavily exploited seamounts, suggesting an important sub

55 e contacts do not become infected, even when heavily exposed.

56 While GluD1 was more heavily expressed in the striosomes than the matrix in t

57 However, unless heavily filtered, LBD generates more potential new knowl

58 Some of these systems have been heavily fished, causing a decline among their historical

59 , the anterior dorsal region (LHAad), stains heavily for PNNs and dense extracellular matrix (PNNs/EC

60 They will be more diminished in size and heavily fragmented (especially in lowland wet forests),

61 rowth rates, indicating that the proteome is heavily geared toward cell division.

62 ce projection electrophoresis to augment the heavily genomic and transcriptomic single-cell atlases w

63 CLC-7 is entirely covered by a dimer of the heavily glycosylated and disulfide-bonded OSTM1, which s

64 Fcalpha receptor (FcalphaRI), which is also heavily glycosylated at its extracellular domain.

65 The mammalian glycocalyx is a heavily glycosylated extramembrane compartment found on

66 identified were mainly large multidomain and heavily glycosylated proteins when compared to the gener

67 Heavily glycosylated S trimers bind to the angiotensin-c

68 bbits is located in an exposed region of the heavily glycosylated trimer that lacks potential N-linke

69 Iso1 was heavily glycosylated with limited ubiquitin ligase activ

70 , less accessible areas, and be missing many heavily hunted species.

71 CD8 T-cell population that resides within a heavily hyperinflammatory milieu.

72 ossible to uncover specific lipids that most heavily impact insulin sensitivity.

73 However, this equilibrium could be heavily impacted by behavioral considerations.

74 a, Cyanobacteria and Proteobacteria but were heavily impacted by climate variables that influenced wa

75 Freshwater ecosystems are heavily impacted by multiple stressors, and a freshwater

76 disturbed area, and the second was much more heavily impacted by research and tourism.

77 The United States has been heavily impacted by the COVID-19 pandemic.

78 emia is conducted in East Tennessee, an area heavily impacted by the opioid crisis and IDU.

79 raws upon the experiences of colleagues from heavily impacted regions of the United States and Europe

80 The specificity of the protease heavily impacted the number of proteins identified.

81 nfish (Pterois spp.) are considered the most heavily impacting invasive marine vertebrate ever record

82 able cortico-limbic scene-processing network heavily implicated in AD pathophysiology.

83 us of the stria terminalis (dBNST), a region heavily implicated in negative affect in both humans and

84 this period, many societies began to invest heavily in building monuments, which suggests an increas

85 s of the underlying genetic discovery weighs heavily in our funding considerations as does the suitab

86 es revealed that although AN and OCD overlap heavily in their shared risk with other psychiatric phen

87 son to be correctly re-identified, even in a heavily incomplete dataset.

88 crobiome succession over time was similar in heavily infected and uninfected plants.

89 ological assays that are biased towards more heavily infected animals.

90 ly isolate millions of immune cells from the heavily infected duodenum.

91 These lymphomas were heavily infiltrated by clonally restricted T cells and f

92 rials in organic electronic devices, as they heavily influence their optoelectronic properties.

93 ds a specialist or a generalist phenotype is heavily influenced by chance.

94 ealed that the distribution of DNA damage is heavily influenced by chromatin states and the binding o

95 etic structure of koala populations has been heavily influenced by human actions, specifically habita

96 een fluorescent protein (GFP) is known to be heavily influenced by hydrogen bonding between the core

97 ectrochemical properties of a solvent can be heavily influenced by its solvation status.

98 riation in discharge opioid prescriptions is heavily influenced by provider routine/bias and not by o

99 5)) concentrations since 2000 have been most heavily influenced by regional changes in sulfate and or

100 netic levels, but rare subcommunity was more heavily influenced by stochasticity (72%) than the abund

101 inated by a small number of individuals, and heavily influenced by superspreading events (SSEs).

102 We found that the perception of speed is heavily influenced by texture: some textures are systema

103 ials towards these described applications is heavily influenced by the choice of molecular building b

104 the distortion of the inorganic framework is heavily influenced by the degree of A' and A alloying.

105 Sea turtle eggs are heavily influenced by the environment in which they incu

106 This arbitrary method is heavily influenced by the mass transport of the electrol

107 These cognitive functions are heavily influenced by the neuromodulator dopamine.

108 Past research has shown that splashing is heavily influenced by the substrate roughness.

109 MXene properties are heavily influenced by their surface chemistry, but a det

110 exposure to a lethal pathogen, one colony is heavily influential to the entire group's survival after

111 and connections one to another, and both are heavily informed by knowledge accumulated from previous

112 strong efferents to these areas but is also heavily innervated by both brain regions.

113 Barrier tissues are heavily innervated by nociceptors, the sensory neurons t

114 The pathways are heavily interconnected and act on a variety of common ef

115 As expected, particles with cyclic RGD were heavily internalized by U87MG (proportional to the pepti

116 (Ailuropoda melanoleuca) is one of the most heavily invested species in conservation.

117 ing synaptic-resolution "holotypes" both for heavily investigated and previously unknown cell types.

118 netics on atomic length scales have not been heavily investigated due to the long times, high reactio

119 h selenide, and bismuth telluride, have been heavily investigated for therapeutic purposes.

120 its in aging human vasculature, has not been heavily investigated.

121 bors a highly specific, coevolved microbiota heavily involved in bee immune function and nutrition.

122 ts show that although supervised learning is heavily involved in VPL of complex natural images, the e

123 (7 g iodine/kg body weight), tumors showed a heavily iodinated rim surrounding the tumor having an av

124 mily members (n = 527) of extended pedigrees heavily loaded for bipolar disorder ascertained from gen

125 These services have been heavily marketed in the United States and often include

126 "Energy drinks" are heavily marketed to the general public, across the age s

127 This indicates that motor resonance is heavily mediated by top-down inputs from both pSTS and D

128 t can help physicians quantify tumor load in heavily metastasized prostate cancer patients.

129 r the observed self-compensation behavior in heavily Mg-doped GaN involving Mg-V(N) complexes.

130 This region has been heavily mined over the past 150 years.

131 netite (Fe(3)O(4)) within the cusps of their heavily mineralized and ultrahard radular teeth.

132 latory actions onto specific mRNAs, are also heavily miRNA-targeted.

133 nt conservation outcome: those that tolerate heavily modified ALCs are 26% more likely to have stable

134 MPO potentially can be heavily modified as it harbors 5 putative N-glycosylatio

135 sable elements (TEs) in the mouse genome are heavily modified by DNA methylation and repressive histo

136 ies-specific glycoconjugates, including ones heavily modified by fucose, sulfate, and sialic acid res

137 iopeptides are a broad class of macrocyclic, heavily modified peptide natural products that are unifi

138 The highest barrier densities occur in the heavily modified rivers of central Europe and the lowest

139 s to enhance sensing capabilities and enable heavily multiplexed assays.

140 uggested that the functional capacity of the heavily myelinated axons were preferentially compromised

141 ated that endothelial adhesion molecules are heavily N-glycosylated, but beyond regulating protein tr

142 etectable glycans, including isomers, on the heavily O-glycosylated protein lubricin.

143 he cell-surface level of endomucin (EMCN), a heavily O-glycosylated single-transmembrane sialomucin,

144 ith's account of resource-rationality relies heavily on a notion of teleology.

145 lease (effluent) via wastewater systems rely heavily on accurate population data.

146 Given that sooty terns rely heavily on associations with sub-surface predators such

147 to provide specificity, cellular assays rely heavily on biomolecular labels and tags while label-free

148 n of these ancient environments has depended heavily on carbon isotopic analysis of fossil bones and

149 ets, with larger mesocarnivores relying most heavily on carrion.

150 Lobsters rely heavily on chemical cues for many biological and ecologi

151 rrent diagnosis of early Lyme disease relies heavily on clinical criteria, including the presence of

152 Current approaches rely heavily on electrode-based devices, but size scalability

153 Bastin et al. present a framework that draws heavily on existing ideas of dual processes in memory in

154 Current models rely heavily on fetal tissues, can be prohibitively expensive

155 Oxidative dearomatizations commonly rely heavily on hypervalent iodine or heavy metals to provide

156 Wound care professionals rely heavily on images and image documentation for proper dia

157 prone regions remains a challenge and relies heavily on in-depth understanding of various driving mec

158 consequences of delayed vaccination depended heavily on influenza season timing, rate of waning, and

159 rent ovonic threshold switching devices rely heavily on intricate control of material stoichiometry a

160 The literature to date has focused heavily on issues surrounding the quality of seroprevale

161 The spirochaete relies heavily on its arthropod host for basic metabolic functi

162 the axon-rich white matter of the brain rely heavily on lactate as a substrate for ATP synthesis.

163 he developing tropics where communities rely heavily on marine-based protein.

164 Methods of evaluating treatments for BD rely heavily on meta-analysis, which is convenient but with i

165 me, a ribonucleoprotein complex that depends heavily on Mg(2+) for structure.

166 coding revealed that ruminant herbivores fed heavily on mimosa, and experimental exclosures confirmed

167 ncreatic beta cells and adipocytes both rely heavily on mitochondrial function in the regulation of o

168 ll mtDNA replication as certain cancers rely heavily on mitochondrial functions.

169 sis and light-emitting diodes, but they rely heavily on molecules containing precious metals such as

170 However, previous studies relied heavily on neurotoxic ablation of NK1R spinal neurons, w

171 tates, and current treatment approaches rely heavily on opioids, which often have limited efficacy an

172 location information in navigation, but rely heavily on optical flow.

173 derstanding of word meaning presumably draws heavily on our nonlinguistic sensory, motor, interocepti

174 ta, a ubiquitous pulmonate snail that grazes heavily on periphyton, exposed to either copper or gold

175 unities in the marine environment often rely heavily on provisioning to ensure the viewing of cryptic

176 n or soybean, sorghum improvement has relied heavily on public research; thus, many of the genetic re

177 e interplay between host and pathogen relies heavily on rapid protein synthesis and accurate protein

178 kinetoplastids such as trypanosomes depends heavily on RNA-binding proteins that influence mRNA deca

179 ries of the most active catalysts still rely heavily on serendipity.

180 go unnoticed when assessment is focused too heavily on simulated data, where the alignment task is o

181 This parameterization relies heavily on soil texture, but overlooks the critical role

182 ments of the value of modified habitats rely heavily on species presence and/or abundance, masking ec

183 Currently quantification relies heavily on staining methods which can be expensive, labo

184 complex environments, older adults rely more heavily on suboptimal reinforcement-learning strategies

185 pproaches to determine tumor boundaries rely heavily on surgeons' expertise, and final histopathologi

186 Proteome characterization relies heavily on tandem mass spectrometry (MS/MS) and is thus

187 gue virus (DENV) and Zika virus (ZIKV), rely heavily on the availability of endoplasmic reticulum (ER

188 In addition, power will depend heavily on the choice of the test statistic and on the u

189 volutionized cancer treatment, and it relies heavily on the comprehensive understanding of the immune

190 e and evidence-based decision-making depends heavily on the credibility of studies and their findings

191 c hematopoietic cell transplantation depends heavily on the delicate balance between the activity of

192 Aquaculture relies heavily on the fish meal and fish oils derived from capt

193 ion, including the rise of dinosaurs, relies heavily on the fossil-rich continental deposits of South

194 selectivity of trifluoromethylation depends heavily on the functional group protection strategy and

195 The study of the human microbiome relies heavily on the genomes of bacterial isolates that can be

196 s just seven known proteins; thus, it relies heavily on the host machinery to replicate.

197 Water stressed regions rely heavily on the import of water-intensive goods to offset

198 The workflow relies heavily on the input of a multidisciplinary team and inv

199 of the glomerular filtration barrier depends heavily on the integrity of lipid rafts, which include s

200 or complex sites, the log-normal fit depends heavily on the number of BDL sites included.

201 recision, the future of this practice relies heavily on the optimization of the cellular microenviron

202 onstructions from high latitudes, which rely heavily on the presence and abundance of pollen from the

203 Human social cognition relies heavily on the processing of various visual cues, such a

204 Current molecular biology laboratories rely heavily on the purification and manipulation of nucleic

205 ness of this collaborative mechanism depends heavily on the relative strengths of endocytic recruitme

206 e-weighted average (TWA) concentrations rely heavily on the robustness of sampling rates.

207 apies, should they be forthcoming, will rely heavily on the use of approved biomarkers or biomarkers

208 ed live attenuated influenza vaccines relies heavily on their ability to induce elevated interferon r

209 nce of spectral deconvolution methods relies heavily on their scoring functions, which distinguish co

210 nd in terrestrial environments and many rely heavily on their silks for fitness related tasks such as

211 We found that PGCCs rely heavily on their uniquely distributed and polarized VIF

212 opharmaceutical and regulatory agencies rely heavily on this technique for characterizations of pharm

213 or early career researchers (ECRs), who rely heavily on timely publication of their work to gain reco

214 transmission of the Hawaiian subtype relies heavily on tumor formation.IMPORTANCE Fibropapillomatosi

215 ements in memory performance, but has relied heavily on univariate approaches (averaging activity acr

216 Modern genomic breeding methods rely heavily on very large amounts of phenotyping and genotyp

217 of Africa, India, and the Middle East relies heavily on virtual water imports by the end of the centu

218 Heading perception in primates depends heavily on visual optic-flow cues.

219 entirely avoided with a strategy that relies heavily on VXM.

220 unoassays or digital-based systems that rely heavily on wash steps and can be run with common and rea

221 early-mid gestation, when pig placentae grow heavily, on placental and fetal development.

222 scount spectrotemporal regions where sources heavily overlap.

223 ly to low-oxidation GQDs, and not at all for heavily oxidized GQDs.

224 e of conservation concern as one of the most heavily poached, yet least understood mammals.

225 uld be applicable not only to individuals in heavily polluted countries, high-risk or susceptible ind

226 viral pathogens and their rapid spread into heavily populated areas around the world underscore the

227 rt (NbM), a subregion of the basal forebrain heavily populated by cortically projecting cholinergic n

228 e dorsal horns of the spinal cord, which are heavily populated with primary afferent sensory neurons.

229 The dysregulation of heavily post-translationally modified ECM proteins direc

230 ethasone has shown activity in patients with heavily pre-treated multiple myeloma.

231 porter (NET-1), shows promising responses in heavily pre-treated neuroblastoma (NB) patients.

232 nt activity in the phase 1 DREAMM-1 study in heavily pre-treated patients with relapsed or refractory

233 imilar to other AHSCT studies despite a more heavily pretreated cohort.

234 Methods: Twenty-two patients with heavily pretreated lymphoproliferative or myeloid malign

235 ing efficacy as monotherapy in patients with heavily pretreated multiple myeloma in the GEN501 and SI

236 activity with a manageable safety profile in heavily pretreated paediatric and adult patients with re

237 In this heavily pretreated patient population, treatment with th

238 In heavily pretreated patients with HER2-positive metastati

239 ncouraging preliminary antitumor activity in heavily pretreated patients with mesothelin-expressing s

240 Heavily pretreated patients with relapsed or refractory

241 esponses and was generally well tolerated in heavily pretreated patients with relapsed or refractory

242 our activity across multiple tumour types in heavily pretreated patients.

243 D-L1-positive population and be done in less heavily pretreated patients.

244 plus next-generation anti-CD20 antibodies in heavily pretreated relapsed or refractory non-Hodgkin ly

245 a manageable safety profile in patients with heavily pretreated RRMM, including those with triple-cla

246 3 of 24 with stage IIB to IV MF/SS) and were heavily pretreated with a median of four prior systemic

247 activity and a manageable safety profile in heavily pretreated, double-refractory iNHL, consistent w

248 a therapeutic opportunity for patients with heavily pretreated, HER2-amplified metastatic colorectal

249 gle-agent clinical activity in patients with heavily pretreated, platinum-refractory metastatic uroth

250 Enrolled patients with mUC (n = 155) were heavily pretreated, with 96% having prior platinum-based

251 CD16a is heavily processed, and recent reports indicate that the

252 kinase-directed precision medicine has been heavily pursued since the discovery and development of i

253 during the low-flow season when habitat was heavily reduced and water demand was highest.

254 lus chemotherapy in paediatric patients with heavily relapsed and refractory acute myeloid leukaemia

255 s in metabolic pathways, tumors often become heavily reliant on antioxidant machinery and may be susc

256 d, most require significant user-tuning, are heavily reliant on dimension reduction techniques and ar

257 Cellular Pi efflux is heavily reliant on Xenotropic and Polytropic Retrovirus

258 Most malaria-endemic countries are heavily reliant upon rapid diagnostic tests (RDT) for ma

259 alinity is shrimp production, which however, heavily relies on antibiotic usage.

260 within the precision agriculture system that heavily relies on drone-borne sensors.

261 one resorption of differentiated osteoclasts heavily relies on increased aerobic glycolysis and glyco

262 However, the interpretation of imaging data heavily relies on the "intuition" of experienced researc

263 ticularly, high quality electrochemical data heavily relies on the availability of high precision cur

264 agement and control of COVID-19 importations heavily rely on a country's health capacity.

265 Prostate cancer (PCa) cells heavily rely on an active androgen receptor (AR) pathway

266 atomistic computer simulations of materials heavily rely on interatomic potentials predicting the en

267 Neurons heavily rely on mitochondrial function, and deficits in

268 and quantification of peptides and proteins heavily rely on sequence database searching or spectral

269 ility, unilateral lower-limb amputees (LLAs) heavily rely on visual and vestibular inputs, and somato

270 Time-to-time technological advancements have heavily revolutionized the field of genomics, especially

271 stological sections of the retina revealed a heavily rod dominated retina containing only a few small

272 Traits of modern crops have been heavily selected in agriculture, leaving commercial line

273 The evolution of baboons has been heavily shaped by climatic changes and population expans

274 ct properties in vivo Sialidase treatment of heavily sialylated CHO-sKlotho increased its co-receptor

275 uces the mass formation of resting spores, a heavily silicified life cycle stage associated with carb

276 t is known that research into human genes is heavily skewed towards genes that have been widely studi

277 e intensities, not stirred and moderately or heavily stirred.

278 new network motif extends the impact of the heavily studied coding benefits of homotypic coupling to

279 port properties of these materials have been heavily studied, there are still key features that are n

280 he combinational chemo- photodynamic therapy heavily suppresses tumor growth and inducing immunogenic

281 s and transport injuries) that have not been heavily targeted by foreign aid and require health-care

282 wild type, rde-11 and sid-1 transcripts are heavily targeted by piRNAs and accumulate in P granules

283 t networks, identifies specific cell classes heavily targeted for serotonergic modulation in the olfa

284 Foxp2 and Pdyn subpopulations project heavily to the hypothalamus, but not to the cortex, basa

285 tively, it keeps proliferating, contributing heavily to the population of differentiating, invasive t

286 Remarkably, cortical regions contributing heavily to the prediction models exhibited distinctive f

287 ween fragmented and fused states that shifts heavily toward fission in response to cellular damage.

288 f GR signaling in two African populations of heavily traumatized individuals: Survivors of the rebel

289 We enrolled heavily treatment-experienced adults (>=18 years) failin

290 However, some people living with HIV who are heavily treatment-experienced have limited or no treatme

291 In heavily treatment-experienced individuals with advanced

292 chment inhibitor, temsavir, is indicated for heavily treatment-experienced individuals with multidrug

293 t options for people living with HIV who are heavily treatment-experienced, and additionally can impr

294 ant in terms of their biodiversity are still heavily under-represented by any type of conservation ef

295 s remains a challenge and coeliac disease is heavily underdiagnosed.

296 af allometry, whose expression is contingent heavily upon the environment.

297 r, polyanionic cathodes reported so far rely heavily upon transition-metal redox reactions for lithiu

298 While many of these applications heavily utilize the alignment of long nucleotide sequenc

299 data-deficient species inhabiting rugged or heavily vegetated terrain.

300 1-15.0 wt %) but dominate the composition of heavily weathered spilled petroleum.