ライフサイエンスコーパス: helix-turn-helix motif

1 s found previously for a naturally occurring helix-turn-helix motif.

2 suspected to be a DNA-binding protein, has a helix-turn-helix motif.

3 lysozyme (residues T115-K135), located in a helix-turn-helix motif.

4 ganized into a nascent helix-turn-helix-turn-helix-turn-helix motif.

5 yb proteins centering on the possession of a helix-turn-helix motif.

6 o known proteins but does contain a putative helix-turn-helix motif.

7 n which is responsible for DNA binding via a helix-turn-helix motif.

8 esence of a conserved C-terminal DNA-binding helix-turn-helix motif.

9 sis of HARS(WHEP) confirmed a well-organized helix-turn-helix motif.

10 pecific contacts to the major groove via its helix-turn-helix motif.

11 a three-helix bundle containing a canonical helix-turn-helix motif.

12 pin domain, a helical hairpin, and bipartite helix-turn-helix motif.

13 d antiparallel beta-barrel and an N-terminal helix-turn-helix motif.

14 the DNA in the classical fashion of a winged helix-turn-helix motif.

15 invariant cysteine residues and a conserved helix-turn-helix motif.

16 ing, form the second helix of an unpredicted helix-turn-helix motif.

17 the major groove contact site as a modified helix-turn-helix motif.

18 confirming that DNA binding is mediated by a helix-turn-helix motif.

19 boxyl-terminal domain binds DNA via a winged helix-turn-helix motif.

20 ly with a beta-barrel body capped by a small helix-turn-helix motif.

21 hosphate repressor which are not part of the helix-turn-helix motif.

22 meodomain protein, which binds DNA through a helix-turn-helix motif.

23 beta-sandwich and a potentially DNA-binding helix- turn-helix motif.

24 er structure in current databases, including helix-turn-helix motifs.

25 Lrp, including complete conservation of the helix-turn-helix motifs.

26 N-terminal DNA-binding domain containing two helix-turn-helix motifs.

27 rientation of the two DNA-interacting winged helix-turn-helix motifs.

28 by a complement of DNA contacts made by two helix-turn-helix motifs.

29 tructural features; embedded zinc ribbon and helix-turn-helix motifs.

30 fies an N-terminal cytoplasmic domain with a helix-turn-helix motif, a transmembrane sequence, and a

31 As one of the few stable helix-turn-helix motifs, alphatalpha is an excellent mod

32 putative recognition helix of the predicted helix-turn-helix motif and a basic region near the C ter

33 degrees rigid body rotations of each winged helix-turn-helix motif and DNA dissociation.

34 Structurally, the region comprises a helix-turn-helix motif and is positioned among the TRP h

35 f the dtxR gene that encodes the DNA-binding helix-turn-helix motif and metal-binding site 1 within d

36 The structure conforms to a helix-bend-helix-turn-helix motif and reveals that the anchor enter

37 ORF157 contains a helix-turn-helix motif and shares no homology with known

38 ra are at residues 78-81, at the turn of the helix-turn-helix motif and the tip of the recognition he

39 ruption of the interface between a conserved helix-turn-helix motif and the top of TMH2.

40 ers of this family, including the C-terminal helix-turn-helix motif and the well-conserved RpoN box.

41 A might use a slightly different part of the helix-turn-helix motif and there appears to be some asso

42 sults for p16; (b) two residues at the first helix-turn-helix motif and two at the third are importan

43 conserved motif that contains a well-folded helix-turn-helix motif and two highly dynamic wings.

44 ed conservation of basic residues within the helix-turn-helix motif and within the beta hairpin loop,

45 This domain, which is comprised of two helix-turn-helix motifs and a beta-hairpin structure, is

46 strongly to DNA through the zinc finger and helix-turn-helix motifs and that DNA binding and catalys

47 minal DNA-binding domain contains the winged helix-turn-helix motif, and the C-terminal presumed regu

48 that connects the helices of a non-canonical helix-turn-helix motif, and through a concomitant struct

49 groove binding wings, an inward movement of helix-turn-helix motifs, and a downward relocation of pl

50 in of AdpA (AdpA-DBD), which consists of two helix-turn-helix motifs, and a target duplex DNA contain

51 extended eukaryotic-like wings, prokaryotic helix-turn-helix motifs, and helix-helix elements.

52 B contains at least three DNA binding winged-helix-turn-helix motifs, and mutations within any of the

53 the DNA free state the backbone atoms of the helix-turn-helix motif are generally immobilized whereas

54 the helical N- and C-termini of hCRF form a helix-turn-helix motif around a turn centered at residue

55 recently, we suggested the possibility of a helix-turn-helix motif around a turn encompassing residu

56 e three-helix bundle protein form the native helix-turn-helix motif as an on-pathway intermediate wit

57 FP and the (13)C chemical shifts supported a helix-turn-helix motif at both pH 5.0 and 7.4 with an al

58 ed amino acid sequence of SusR protein had a helix-turn-helix motif at its carboxy-terminal end, and

59 The ARID (A-T Rich Interaction Domain) is a helix-turn-helix motif-based DNA-binding domain, conserv

60 This requires a putative helix-turn-helix motif between residues 88 and 108.

61 e DNA-binding domain of SimR has a classical helix-turn-helix motif, but it also carries an arginine-

62 a protein containing a potential DNA-binding helix-turn-helix motif close to its N terminus.

63 A DNA-binding helix-turn-helix motif close to the N terminus of gp16 i

64 alpha helices, of which the middle 2 form a helix-turn-helix motif closely related to that of Drosop

65 al region, the protein sequence contains the helix-turn-helix motif common to many DNA binding protei

66 bundle containing a pseudo 2-fold axis and a helix-turn-helix motif commonly found in DNA-binding pro

67 The structure also reveals a helix-turn-helix motif containing an arginine-rich alpha

68 E217 TerS contains both N-terminal helix-turn-helix motifs enriched in basic residues and a

69 The many alpha-helical HEAT repeats (helix-turn-helix motifs) facilitate bending and allow th

70 NrpR contained a putative N-terminal winged helix-turn-helix motif followed by two mutually homologo

71 The N-terminal domain carries a winged helix-turn-helix motif for binding to DNA and is primari

72 SpoIIID was predicted to have a helix-turn-helix motif for sequence-specific DNA binding

73 irF, it may use both of its carboxy-terminal helix-turn-helix motifs for DNA interaction, and may als

74 logs with 98% identity overall and identical helix-turn-helix motifs, for which a previous study neve

75 Two monomers of the helix-turn-helix motif form an antiparallel dimer as ori

76 r exchangeable apolipoproteins comprises the helix-turn-helix motif formed of four 11-mer sequence re

77 for the interaction and that Asp(18) of the helix-turn-helix motif forms a component of the interact

78 n an abiotic host while curiously resembling helix-turn-helix motif found in DNA binding proteins.

79 SmtB displays the classical helix-turn-helix motif found in many DNA-binding protein

80 ratricopeptide repeat (TPR), a 34 amino acid helix-turn-helix motif found in tandem arrays in many na

81 The structure reveals that a novel helix-turn-helix motif, found in NRPS R domains but not

82 Intriguingly, the helix-turn-helix motif, frequently used to recognize B-D

83 four-helix bundles formed by the pairing of helix-turn-helix motifs from two subunits; by means of a

84 ognition: anti-parallel beta strands (MetR), helix-turn-helix motif + hinge helices (PurR), and zinc

85 -binding site into the engrailed homeodomain helix-turn-helix motif (HTH).

86 tilt) from central helix C, positioning the helix-turn-helix motif in an unfavorable position for th

87 okaryotic DNA-binding proteins with a single helix-turn-helix motif in its ability to bind DNA monome

88 The -35 promoter region is recognized by a helix-turn-helix motif in region 4, while the -10 region

89 dues throughout the recognition helix of the helix-turn-helix motif in region 4.2, in contrast to DNA

90 ed a common orientation of the proposed ECL2 helix-turn-helix motif in the binding cavity of cCPE: re

91 ospecific interactions between the BRE and a helix-turn-helix motif in the C-terminal cyclin repeat o

92 Here, we show that the positively charged helix-turn-helix motif in the carboxy terminus (CTD) is

93 A helix-turn-helix motif in the crystal structure of human

94 es 28-35, which form the second helix of the helix-turn-helix motif in the crystal structure, do not

95 This peptide corresponds to the end of a helix-turn-helix motif in the IN(1-55) NMR structure and

96 g method, we found that ATR interacts with a helix-turn-helix motif in the minimal DNA-binding domain

97 es a 137-amino acid protein with a potential helix-turn-helix motif in the N-terminal domain, charact

98 We unravel a short helix-turn-helix motif in the proximal N-terminus, which

99 Our results indicate a conserved helix-turn-helix motif in the type I and type II D/D dom

100 s of mthCdc6-1 mutants demonstrates that the helix-turn-helix motif in the winged-helix domain mediat

101 w minor grooves using the separation between helix-turn-helix motifs in the Fis dimer as a ruler.

102 in the spatial relationship between the two helix-turn-helix motifs in the Fis dimer upon DNA bindin

103 and characterization generated a 24-residue helix-turn-helix motif, including a 13-residue insertion

104 The BtgA protein was predicted to contain a helix-turn-helix motif, indicating possible DNA binding

105 he complex, the alpha/beta-type SASP adopt a helix-turn-helix motif, interact with DNA through minor

106 d PerA protein that contains the DNA-binding helix-turn-helix motif is 100% conserved in all strains

107 Here we show that R432 within the helix-turn-helix motif is critical for sequence-specific

108 Since the distance between the two helix-turn-helix motifs is too great to allow binding to

109 The second helix in the helix-turn-helix motif lies deep in the major groove wit

110 tertiary structure of p16INK4A contains four helix-turn-helix motifs linked by three loops.

111 activator at a domain within or close to the helix-turn-helix motif located at the C terminus of the

112 During pore formation, the helix-turn-helix motif moves away from the bend in the c

113 Although the single Myb-type helix-turn-helix motif of a TRF1 monomer can interact wi

114 we obtained direct evidence that the central helix-turn-helix motif of EsxA inserted into the membran

115 The helix-turn-helix motif of I gamma, however, differs from

116 tein interaction; the protruding hydrophobic helix-turn-helix motif of one subunit fits into a groove

117 al half-site sequence for recognition by one helix-turn-helix motif of one TrpR dimer is 3'CNTGA5'5'G

118 ns with the invariant Arg383 in the putative helix-turn-helix motif of the DNA-binding domain substit

119 g domains has verified the assignment of the helix-turn-helix motif of the transcriptional regulators

120 We show that the cytoplasmic helix-turn-helix motif of Thermotoga maritima RodZ direc

121 that the ATR-XPA interaction mediated by the helix-turn-helix motif of XPA plays an important role in

122 igO2 structures reveals the distance between helix-turn-helix motifs of each HigA monomer increases b

123 The putative helix-turn-helix motifs of Jerky can also bind double-st

124 of alpha-helices in a series of right-handed helix-turn-helix motifs organized into a long rod of len

125 ternary structural change that moves the two helix-turn-helix motifs out of register with successive

126 hat for DNA binding, ComA uses the conserved helix-turn-helix motif present in other NarL family memb

127 and the unprecedented close spacing between helix-turn-helix motifs present in the apodimer is accom

128 domain containing two functionally separable helix-turn-helix motifs, resembling the paired domain of

129 ve examined the nature of the highly charged helix-turn-helix motif (S3b and S4) to address how a hig

130 s a unique fold in which three tandem winged helix-turn-helix motifs scaffold a positively charged co

131 The product of devH contains a helix-turn-helix motif similar to the DNA binding domain

132 whose amino acid sequence contains a winged helix-turn-helix motif similar to the DNA-binding domain

133 In addition to a predicted helix-turn-helix motif, SpoIIID has a C-terminal basic r

134 uelae and that it binds FtsZ via a conserved helix-turn-helix motif, stimulating the assembly of FtsZ

135 Its predicted helix-turn-helix motif suggested that it has a role as a

136 The helix-turn-helix motif, termed "DELSEED-loop," in the C-

137 Each HigA monomer contains a helix-turn-helix motif that binds to its own DNA operato

138 The structure reveals a helix-turn-helix motif that dimerizes to form an antipar

139 ignificant helical secondary structure via a helix-turn-helix motif that inserts the central hydropho

140 Helices 4 and 5 form a classic helix-turn-helix motif that is the putative DNA binding

141 r of the growing IRF family, revealing a new helix-turn-helix motif that latches onto DNA through thr

142 tratricopeptide repeat (TPR) is a 34-residue helix-turn-helix motif that occurs as three or more tand

143 o acid region which potentially folds into a helix-turn-helix motif that specifically binds to the Ca

144 ectors; namely, an outer layer of helix-turn-helix-turn-helix motifs that are packed onto the barrels

145 otein is composed of four ankyrin repeats (a helix-turn-helix motif) that stack linearly as two four-

146 o the binding cavity, which is formed by the helix-turn-helix motif, the betaC-betaD turn and the bet

147 conformational fluctuations that adjust the helix-turn-helix motif to open or close the top of the b

148 e phage excisionases may use variations of a helix-turn-helix motif to recognize specific DNA sequenc

149 anges needed to allow the DNA-binding winged helix-turn-helix motifs to interact with the consecutive

150 gions of the two subunits organized with two helix-turn-helix motifs; two globular flaps extending in

151 gntR product is 331 amino acids long, with a helix-turn-helix motif typical of a regulatory protein.

152 n and around the PobR region that contains a helix-turn-helix motif, whereas mutations causing defect

153 a dinucleotide folds but includes an unusual helix-turn-helix motif which extends from the central be

154 ins two regions resembling the characterized helix-turn-helix motif which is involved in DNA recognit

155 and another lysine, from the 'turn' of the 'helix-turn-helix' motif, which binds downstream and on t

156 FitA has a potential helix-turn-helix motif, while the deduced sequence of Fi

157 The ORF14 protein contains a helix-turn-helix motif, while the ORF16 upstream region

158 main caused by a 6-9 degrees rotation of the helix-turn-helix motif with respect to the rest of the m

159 R, encodes a 22-kDa protein which contains a helix-turn-helix motif with sequence identity to DNA bin

160 phaalphabeta subunits are characterized by a helix-turn-helix motif with sequence signature GxxG at t

161 he long, flexible loop between them form the helix-turn-helix motif, with the third helix being the r

162 th a prediction that DNA binding is due to a helix-turn-helix motif within this region.

163 y binding to voltage-sensor paddles, crucial helix-turn-helix motifs within the voltage-sensing domai