ライフサイエンスコーパス: help elucidate

1 These findings may help elucidate a deeper mechanistic understanding of the

2 key F. tularensis effector protein, and may help elucidate a mechanistic understanding of F. tularen

3 ething rarely done in a range-limit context, helps elucidate a mechanistic understanding of range con

4 within cellular and animal models as well as help elucidate aberrant proteolytic function correlated

5 systemic disease in broad strokes, which may help elucidate AD pathophysiology and to allow for new w

6 ht interfere with essential MA functions and help elucidate additional features of MA binding.

7 g modes within the intasome active sites and helped elucidate an important mechanism of viral resista

8 enase-2 inhibitors with regional blocks, may help elucidate and clarify the true benefits of perioper

9 re no published Guanche autosomal genomes to help elucidate and directly test this hypothesis.

10 A relatively unbiased method, as such, will help elucidate any potential associations between advers

11 selective, sensitive, and rapid method will help elucidate any potential associations between human

12 This study helps elucidate basic mechanotransduction properties tha

13 mechanisms underlying these associations may help elucidate biological mechanisms influencing sleep d

14 iated with early-stage neurodevelopment will help elucidate biological mechanisms involved in neuro-b

15 eterogeneity of colorectal neoplasia and may help elucidate carcinogenic mechanisms for distinct path

16 o-profiling of rare cell populations and may help elucidate correlates of protection for a variety of

17 occur during senescence/immortalization may help elucidate crucial events that lead to cell transfor

18 polymerization rate, while DFT calculations helped elucidate crucial intermolecular interactions bet

19 An Fe(2+)/Fe(3+) redox couple was used to help elucidate details of the band diagram.

20 abnormal mesocarp cell differentiation could help elucidate determinants of fruit cell fate maintenan

21 emonstrates how a computational approach can help elucidate developing ELNs and their impact on tumor

22 These results help elucidate differences between the initial negative

23 nical and biomarker fingerprint profiles may help elucidate disease subtypes as well as response to t

24 Our new coding regions help elucidate disease-associated regions by revealing t

25 l inconsistencies between similar components help elucidate DOM properties for which fluorescence spe

26 reinforcement learning techniques that have helped elucidate dopamine's role in appetitive behavior.

27 ical and genomic profiling technologies have helped elucidate early and late diversification mechanis

28 arking risk for psychotic illness and it may help elucidate etiological underpinnings of psychotic di

29 To help elucidate expansin's mechanism of wall loosening, w

30 method will find a significant hit that can help elucidate function.

31 equencing of protein-coding genes, which can help elucidate functional differences among microbial co

32 This tool is expected to help elucidate fundamental physiological and pathologica

33 ng with the recent advances in genetics, has helped elucidate further roles of primary cilia beyond s

34 These insights may help elucidate future adoptive immunotherapeutic approac

35 patiotemporal context of expression data and help elucidate gene function.

36 Their combined use can help elucidate gene regulation 'logic' by aiding in targ

37 CML and its progression to blast crisis may help elucidate general mechanisms of carcinogenesis and

38 ogonal RNA transcription regulators, and may help elucidate general principles of non-coding RNA regu

39 ioral measures linked to brain circuitry can help elucidate genetic mechanisms contributing to defici

40 for regulatory factor interactions that will help elucidate genome function and the implementation of

41 vide new drug and vaccine targets and should help elucidate hookworm pathogenesis.

42 body assembly and maturation to date and may help elucidate how abscission sites are positioned and r

43 These results help elucidate how cortical processing exploits spatial

44 These findings help elucidate how diverse genetic risk factors converge

45 These findings can help elucidate how faster processes can organize, transp

46 To help elucidate how general the role of dopamine (DA) rel

47 Our studies help elucidate how HSV gE/gI and US9 promote the assembl

48 n of other potential disease mechanisms will help elucidate how PLG contributes to OM susceptibility

49 The characterization of mutant lines can help elucidate how recombination is controlled.

50 dy mass and its demographic consequences can help elucidate how social and environmental factors affe

51 nmental field work, laboratory evolution may help elucidate how these bacteria have so successfully a

52 es that regulate EGFR signaling in vivo will help elucidate how this pathway can become inappropriate

53 e to EBV and disease risk across cancers may help elucidate how this ubiquitous virus contributes to

54 Model systems have helped elucidate how secretion systems function at both

55 broader view of neural circuit dynamics and helping elucidate how brain regions work in concert to s

56 Genomic biology offers promise in helping elucidate in greater detail how nutrient utiliza

57 ll the proposed computational frameworks can help elucidate input/output relationships of signaling n

58 In order to help elucidate its function, we undertook a determinatio

59 tion and fibrillation pathway of hSAA1.1 may help elucidate its pathological role.

60 tion of C9orf72 protein isoforms, which will help elucidate its physiological function and role in AL

61 AcroB may help elucidate key aspects of mitochondria electrophile

62 These results should help elucidate Li(+) intercalation motifs between curved

63 a can, with great spatiotemporal resolution, help elucidate local disease patterns.

64 These results may help elucidate lower than expected mortality rates obser

65 ts luminally exposed to high CO(2) saline to help elucidate luminal acid-sensing mechanisms.

66 interest since its discovery in 1980 and has helped elucidate many important aspects of quantum physi

67 Further genomic and functional analyses may help elucidate mechanisms by which tumor cells metastasi

68 ed spermatogonia, including SSCs, which will help elucidate mechanisms controlling the earliest cell

69 These investigations were conducted to help elucidate mechanisms for improving olefin hydrogena

70 Results from this and future cases may help elucidate mechanisms of antitumor immunity and allo

71 notypes associated with expression and could help elucidate mechanisms of intestinal disease.

72 C2-8 provides an essential tool to help elucidate mechanisms of neurodegeneration in HD and

73 preventive HIV-1 vaccine efficacy trial can help elucidate mechanisms of partial protection.

74 Understanding this difference may help elucidate mechanisms of pathogenesis.

75 udy of the loci identified in this study may help elucidate mechanisms of phosphorus regulation.

76 s to paired computational studies that often help elucidate mechanisms of the observed behavior.

77 e models with direct CD4 alloreactivity will help elucidate mechanisms of transplant rejection and to

78 They help elucidate mechanisms underlying campomelic dysplasi

79 wed for imaging of specific activity and has helped elucidate mechanisms of action for ROS.

80 res from a full repertoire of potential ones helps elucidate mechanisms of cancer development.

81 In addition, this methodology may help elucidate mechanistic pathways linking diet to chro

82 ood agreement with available experiments and help elucidate melanin's role in photoprotection against

83 contributions, these markers show promise to help elucidate mnemonic processing in TLE.

84 xpression profiling and ER protein assays to help elucidate molecular mechanism(s) responsible for ta

85 ors often use these datasets individually to help elucidate molecular mechanisms of human diseases.

86 NSAC1003 will help elucidate molecular mechanisms of RecBCD-Chi regula

87 Mouse models have helped elucidate MYCN functions; however its cardiac-spe

88 Our results help elucidate nanomedicines' in vivo fate and provide g

89 These findings help elucidate neural mechanisms of anhedonia, as a step

90 These findings help elucidate neurochemical substrates of choice, with

91 fication of numerous mutants whose study has helped elucidate new mechanisms in cardiac development.

92 sq1) mice might represent a valuable tool to help elucidate novel aspects of TLR7 biology.

93 suprachiasmatic nucleus, these findings will help elucidate novel mechanisms modulating circadian flu

94 Similar studies could help elucidate other DNA enzymes with activities coordin

95 ncer profiles, we showed that using pi-value helps elucidating otherwise overlooked important biologi

96 hanges seen in malnourished children and may help elucidate our understanding of long-term metabolic

97 These findings help elucidate possible mechanisms of nitrite-induced ca

98 results also show how a systems approach can help elucidate potential mechanisms of action and advers

99 at nanoscale remains a challenge that could help elucidate processes in biology, medicine and techno

100 Indeed, models can help elucidate properties of these networks, understand

101 y computational tools have been developed to help elucidate protein function.

102 sA from Streptomyces lividans can be used to help elucidate questions about channel inactivation and

103 traits influenced by a common group of genes helps elucidate regulatory networks and can improve link

104 Our proposed method may help elucidate relationships among key mutations and the

105 Eye tracking has helped elucidate relationships between eye movements, vi

106 analyses of the differentiation system have helped elucidate roles of chromatin state, transcription

107 binding sites around alternative exons will help elucidate splicing regulation by RBPs.

108 in vitro hydrogenase activation methods have helped elucidate steps in the H-cluster biosynthetic pat

109 otspots at mutant amino acid resolution will help elucidate the allele-specific differences in their

110 These findings help elucidate the amino acid side chains involved in DN

111 model of the ICE electric field was used to help elucidate the antifouling mechanism in solution.

112 These findings may help elucidate the apparently contradicting results of c

113 To help elucidate the assembly mechanism of the nucleocapsi

114 ell as the analytical method, can be used to help elucidate the axonal transport impairments observed

115 human non-small cell lung cancer (NSCLC) may help elucidate the basis for its dismal prognosis.

116 umbers, a larger multi-institution study may help elucidate the benefits of T2 mapping as an adjuncti

117 Specific inhibitors may also help elucidate the biochemical roles of each Hsp90 paral

118 stratification may reduce heterogeneity and help elucidate the biological basis of complex neuropsyc

119 the potential for this monogenic disorder to help elucidate the biological features of idiopathic aut

120 To help elucidate the biological function of PRMT6 in vivo,

121 isease status but also cognitive function to help elucidate the biological pathway from gene to brain

122 Our results can help elucidate the biological roles that TE play in the

123 These findings may help elucidate the biological validity of similar findin

124 ating activity of the amygdala in humans and help elucidate the causal neural interactions that under

125 Further study of SSPCs may help elucidate the cellular and molecular mechanism of s

126 Ice-COLD-PCR will help elucidate the clinical significance of low-abundanc

127 In sum, our comprehensive data help elucidate the complex binding landscape of C2H2-ZF

128 These findings help elucidate the complex communication that occurs in

129 These findings help elucidate the complex nature of CD28 gene regulatio

130 These findings may help elucidate the connection between key local events a

131 he findings constitute new evidence that may help elucidate the consequences of H.M.'s operation in t

132 f selection to aging within a population and help elucidate the contribution of aging itself to the v

133 Our method should help elucidate the contribution of mosaic somatic mutati

134 llular trafficking of PrP(C) may, therefore, help elucidate the conversion process.

135 ween consolation and empathy, these findings help elucidate the development of individual socio-cogni

136 ts with pediatric bipolar disorder (PBD) can help elucidate the developmental origins of altered stru

137 These mechanisms may help elucidate the differential mutational statistics in

138 three complementary animal models that will help elucidate the disease mechanism.

139 neation of such defining characteristics may help elucidate the etiology and prognosis of such tumors

140 n be relatively safe in this population, may help elucidate the etiology of renal failure, may predic

141 sed attention to events in this interval may help elucidate the etiology of TGCTs.

142 c regulation of melanoblast development will help elucidate the etiology of these and other neurocris

143 ng commonalities between lncRNA systems will help elucidate the evolution and mechanistic role of lnc

144 ous with vertebrate neurulation and thus may help elucidate the evolutionary origin of the brain.

145 studies of the kinetics of [(18)F]FSPG will help elucidate the factors mediating a decline in [(18)F

146 Our findings help elucidate the factors structuring marine mammal mic

147 Calculations help elucidate the factors that underlie the selective b

148 tly enhanced reproducibility are expected to help elucidate the formation mechanism of this interesti

149 oteins and their structural interactions may help elucidate the formation of the polar tube during th

150 iptional meta-analysis was also conducted to help elucidate the function of the CLE peptide family me

151 Studies of THRUMIN1 will help elucidate the function of this family of eukaryotic

152 These findings help elucidate the functional differences that result fr

153 To help elucidate the functions of the large number of PFam

154 um of laboratories utilizing metabolomics to help elucidate the functions of uncharacterized genes.

155 entification of an inner activation gate can help elucidate the gating and permeation mechanism of TM

156 We propose that this SthK model will help elucidate the gating mechanism of CNG channels.

157 d pathways, and cellular phenotypes that may help elucidate the genetic basis of childhood HSE.

158 landraces from a broad geographical range to help elucidate the genetic basis of local adaptation.

159 ferences obtained from experimental data and help elucidate the homeostatic mechanisms underpinning t

160 This work should help elucidate the hydrolytic ring-opening mechanism of

161 ron and high resolution x-ray diffraction to help elucidate the identity of the catalytic base in the

162 The two boundaries help elucidate the in vivo binding structure of a given

163 lity of intermolecular interactions may also help elucidate the interactions of the molecular nanofib

164 These findings help elucidate the link between compulsive eating and an

165 arine ecosystem in the Northeast Pacific can help elucidate the magnitude of assemblage shifts, and w

166 y of selective pressures on individuals will help elucidate the maintenance of microbial diversity an

167 ns ubiquitous in key cellular processes, and help elucidate the mechanism and pathological significan

168 ng a catalytic intermediate that promises to help elucidate the mechanism of catalysis.

169 ribution and evolution of these sites and to help elucidate the mechanism of frameshifting, we determ

170 KvDMR1 into its functional components should help elucidate the mechanism of its function in vivo.

171 Our study provides new data that will help elucidate the mechanism of PM10-mediated lung cance

172 To help elucidate the mechanism of protein inactivation med

173 ponse induced by the vaccine have promise to help elucidate the mechanism of SAEs.

174 define the role of OTT1 in hematopoiesis and help elucidate the mechanism of t(1,22) acute megakaryoc

175 ork was to obtain new information that might help elucidate the mechanism of T2 distribution in muscl

176 These findings may help elucidate the mechanism underlying arterivirus repl

177 ion of these findings in further studies may help elucidate the mechanisms behind this short-term inc

178 To help elucidate the mechanisms behind XMRV infection, we

179 APOL1 may provide clues that will ultimately help elucidate the mechanisms by which APOL1 variants pr

180 expression in response to E2F-1 in order to help elucidate the mechanisms by which E2F-1 causes apop

181 ow mutant TBP mediates neuropathology should help elucidate the mechanisms by which transcriptional d

182 gulators during internode morphogenesis will help elucidate the mechanisms coordinating axial growth

183 pattern of T cell differentiation that might help elucidate the mechanisms of HCV immunity and pathog

184 ering protective genetic variants that could help elucidate the mechanisms of Mendelian diseases and

185 rge capacity and hydrogen bonding, which can help elucidate the mechanisms of other heterogeneous ele

186 SA signaling network in plants, and may also help elucidate the mechanisms through which SA acts as a

187 We anticipate that these findings will help elucidate the mechanisms underlying HCM development

188 epts and simplifying modeling approaches may help elucidate the mechanisms underlying other cellular

189 To help elucidate the mechanisms underlying this phenomenon

190 fold and unfold, have recently been used to help elucidate the mechanistic principles that underlie

191 residues at the inhibitor-binding site will help elucidate the molecular basis for fusion activation

192 These findings help elucidate the molecular basis for the mixing vessel

193 crystal structures and enzymological studies help elucidate the molecular basis of LovC specificity,

194 aspartate-prone proteins identified here may help elucidate the molecular basis of one or more develo

195 transcriptional regulatory sites in vivo to help elucidate the molecular basis of sex-related differ

196 Expression profiling of pure DCIS will help elucidate the molecular characteristics that distin

197 al outcome of a mutation, and can be used to help elucidate the molecular mechanism of disease/cancer

198 Our findings help elucidate the molecular mechanisms by which transcr

199 The results help elucidate the molecular mechanisms for SD inducing

200 These models also help elucidate the molecular mechanisms of corneal epith

201 Identification of the causal alleles will help elucidate the molecular mechanisms responsible for

202 ypoparathyroidism-associated GCMB mutations, help elucidate the molecular mechanisms underlying DNA-b

203 These data help elucidate the molecular requirements for activation

204 tionary success of the ssDNA viruses and may help elucidate the mystery of integrated RNA viruses in

205 and functional ortholog of mammalian MCH and help elucidate the nature of MCH evolution among vertebr

206 lysis of intrinsic connectivity networks may help elucidate the neural architectures that support fun

207 These findings help elucidate the neural systems-level effects of methy

208 s of OT and OTR in social recognition should help elucidate the neurobiological bases of human disord

209 factors that enhance preference for risk may help elucidate the neurobiological mechanisms underlying

210 k towards postmortem human brain research to help elucidate the neurobiological underpinnings of MRI

211 These results not only help elucidate the origins of the TM(n+):TiO(2) DMS ferr

212 e remains are subject to intensive study and help elucidate the palaeoenvironment where these animals

213 Our findings help elucidate the paracrine signaling events activated

214 rther characterization of Vitamin D/VDR will help elucidate the pathogenesis of various human disease

215 The double-mutant mice will help elucidate the pathophysiological mechanisms underly

216 novel mouse model of BONJ-like disease will help elucidate the pathophysiology of BONJ and ultimatel

217 choroidal vasculature at variable depths may help elucidate the pathophysiology of disease and can co

218 chronic inflammatory disease models that can help elucidate the pathophysiology of vascular inflammat

219 sensitive detection of CCC DNA, which should help elucidate the pathways of CCC DNA formation and the

220 nd pathways governing liver development will help elucidate the physiological and pathological proces

221 and temporal resolution in intact organs may help elucidate the players involved.

222 ion in this model of open-angle glaucoma may help elucidate the primary changes occurring at the mole

223 ormational effects, the study of which might help elucidate the proton-coupled electron-transfer mech

224 These results could help elucidate the protumor mechanisms of iCAFs.

225 and intraocular pressure measurements, which help elucidate the relationship between corneal properti

226 s pave the way for further investigations to help elucidate the relationships between telomere length

227 s of neonatal Kiss1 and ERs mRNA levels will help elucidate the relative roles each plays in the sex-

228 ease and suggest research avenues that might help elucidate the role of activated platelets in CF.

229 Controlled clinical trials now underway will help elucidate the role of AVP receptor antagonism in th

230 echanisms of microRNA transcription, and can help elucidate the role of microRNA as mediators of comp

231 e and host-microbe chemical cross-talk would help elucidate the role of our gut microbiota in health

232 he Cu-induced transcriptome generated should help elucidate the role of the Cu response in maintainin

233 To help elucidate the role of the gp41 CT in HIV-1 transmis

234 ties influence the metabolic environment may help elucidate the role of the microbiota in disease dev

235 eloped based on binding domain structures to help elucidate the role of this enzyme in the central ne

236 This strategy is poised to help elucidate the role of variants at the low end of th

237 Genomic maps of DNA G-quadruplexes (G4s) can help elucidate the roles that these secondary structures

238 o budget-based global OH constraints and can help elucidate the spatial and temporal variability of O

239 is mouse model provides a powerful system to help elucidate the specific metabolic mechanisms that un

240 cyclin degradation that we report here could help elucidate the specific roles of the redundant CDK-c

241 The results help elucidate the structural origins of the extreme ant

242 campus, and provides a promising approach to help elucidate the synaptic basis of long-term memory.

243 temporally distinct, and this difference may help elucidate the therapeutic window for use of antivir

244 EYA-SO targets identified in this study will help elucidate the transcriptional circuitries whereby o

245 Whole-genome sequencing (WGS) can help elucidate the transmission route of nosocomial path

246 or a broad array of imaging applications and help elucidate the underlying biologic processes relevan

247 known functional information into GWASs can help elucidate the underlying biological mechanisms and

248 eeded in these secondary forms of disease to help elucidate the underlying cause and pathogenesis of

249 nd understanding their normal functions will help elucidate the underlying causes of these disorders.

250 discoveries with psychological processes and help elucidate the underlying neural mechanisms.

251 dividual differences in brain morphology may help elucidate the underlying pathophysiology of bipolar

252 We propose a mathematical model that may help elucidate the underlying physiological mechanism re

253 mplications for arbovirus evolution and will help elucidate the viral factors responsible for the bro

254 Recent studies helped elucidate the cellular and molecular basis of PDC

255 ppaB in complex with diverse kappaB DNA have helped elucidate the chemical principles that underlie t

256 ng individuals in households or schools have helped elucidate the determinants of transmission in sma

257 nsfer in donor-bridge-acceptor molecules has helped elucidate the distance dependence of electron tra

258 erate to large contemporary case series have helped elucidate the early natural history, presenting c

259 abricated and nanofabricated structures have helped elucidate the effects of nanoscale spatial confin

260 ithin- versus between-individual variability helped elucidate the factors contributing to the conside

261 nt studies using Cre-LoxP recombination have helped elucidate the function of LRP1 in mature normal a

262 Insights from basic science research have helped elucidate the mechanisms by which metabolism-base

263 This has helped elucidate the mechanisms of several mutations and

264 tion of the HJ in three different directions helped elucidate the structures of the transient species

265 insight into the behaviors of microtubules, helping elucidate the mechanism of chromosome segregatio

266 In addition to helping elucidate the role of B cells in MS, our approac

267 Our work helps elucidate the ambiguity concerning the role of TGF

268 onale for selectivity at the molecular level helps elucidate the biological function and design of sp

269 Mathematical modeling helps elucidate the biological mechanisms at play as the

270 resolution of the conformational transitions helps elucidate the complex chaperone machinery.

271 This work helps elucidate the design rules by which simple logic c

272 ed explanatory variables is developed, which helps elucidate the factors contributing to elevated (22

273 Using our method, we provide a resource that helps elucidate the functional and spatial organization

274 ias directed movement along microtubules and helps elucidate the intricate intracellular sorting obse

275 ain coarsening in the plasticized film which helps elucidate the mechanism by which additives improve

276 e and function of these infectious particles helps elucidate the mechanism by which extracellular ves

277 The resource helps elucidate the modulation of a stimulus by interact

278 tractile property of cardiomyocytes not only helps elucidate the pathophysiology of heart failure but

279 This finding helps elucidate the relative role of surface exposure of

280 tic step performed by key conserved residues-helps elucidate the structure-function relationships of

281 rity analysis of biological time series data helps elucidate the varying dynamics of biological syste

282 hem into chemically meaningful fragments can help elucidate their functional properties, and may be u

283 g TEELs with nucleotide precision, which can help elucidate their molecular origins.

284 Genetic association studies may help elucidate their origin and function.

285 ties of pesticide exposure, they nonetheless help elucidate their risks to colony health.

286 ontrolling cellular processes with light can help elucidate their underlying mechanisms.

287 To help elucidate these roles, we have characterized the fi

288 emand with spatial and temporal precision to help elucidate this important and dynamic process.

289 To help elucidate this process, we examined the binding act

290 bolites, which reflect dietary response, may help elucidate this role.

291 ng a set of microarray samples as input, can help elucidate tightly coexpressed gene sets (modules) t

292 enhance the electrocatalytic performance and help elucidate underlying mechanisms.

293 cation of changes most specific to HFpEF may help elucidate underlying pathophysiology.

294 annotation of the mammalian genome that will help elucidate various human disease genes and pathways.

295 tional redundancy for Drpr in Drosophila may help elucidate whether paralogs of MEGF10 in humans (eg,

296 researchers to conduct systematic reviews to help elucidate whether there is a replication crisis.

297 This new understanding helps elucidate which microstructural features need to b

298 contacts than from drinking water, which may help elucidate why interventions focused on water withou

299 ell compartments uniquely place zebrafish to help elucidate why mammals possess such low capacity to

300 Thus, these simulations also help elucidate why some inhibitory serpin families are m