ライフサイエンスコーパス: helper T-cell

1 d steering their interaction with follicular helper T cells.

2 ne profile favoring the generation of Type 1 helper T cells.

3 e network controlling the differentiation of helper T cells.

4 4, which allowed stable expression of Cd4 in helper T cells.

5 ter B cell support by PG-specific follicular helper T cells.

6 molecule CD28 is essential for activation of helper T cells.

7 d T cells, especially in the TH17 lineage of helper T cells.

8 he development of IL-17-producing pathogenic helper T cells.

9 per cell type 17 (T(H)17), and of follicular-helper T cells.

10 or typically expressed by the TH17 subset of helper T cells.

11 -)Sirpalpha(+) DCs induced the TH1 subset of helper T cells.

12 ity to differentiate into the TH17 subset of helper T cells.

13 chanism did not appear to be shared by mouse helper T cells.

14 in controlling the proallergic generation of helper T cells.

15 trong CD4 cytokine response involving type 1 helper T cells.

16 ferentiation into the TH2 and TH9 subsets of helper T cells.

17 phabeta(+) cytotoxic T lymphocytes or CD4(+) helper T cells.

18 ediated functional differentiation of CD4(+) helper T cells.

19 ewildering number of fates seem possible for helper T cells.

20 tion ex vivo by LN CD4(+)CXCR5(+) follicular helper T cells.

21 with the T(H)1, T(H)17 and T(H)22 subsets of helper T cells.

22 iated into pro-inflammatory T(H)1 and T(H)17 helper T cells.

23 1(+) (V6, P = .003; V8, P = .002) follicular helper T cells.

24 preciated metabolic control of plasticity in helper T cells.

25 ernalization and presentation of antigens to helper T cells.

26 efined here as synaptic ectosomes (SE), from helper T cells.

27 uggesting a large pool of S. aureus-reactive helper T-cells.

28 tokine produced by regulatory T-cells and by helper T-cells.

29 ncreases proliferation of cytotoxic, but not helper, T cells.

30 autoimmune diseases through differentiating helper T cell 1 (TH1) and maintaining TH17 responses.

31 F-alpha ratio and suppressed proinflammatory helper T cell 1 (Th1) cytokine expression by autologous

32 wn-regulated pathogenic pro-inflammatory and helper T cell 1 (Th1) responses and up-regulated benefic

33 IV) disease progression is associated with a helper T cell 1 (Th1) to helper T cell 2 (Th2) cytokine

34 rmine whether blockade of the interleukin 23-helper T cell 17 (IL-23-TH17) pathway with ustekinumab r

35 s associated with a helper T cell 1 (Th1) to helper T cell 2 (Th2) cytokine profile switch.

36 n particular, nicotine is found to promote a helper T cell 2 adaptive immunologic response within T c

37 FIV employs a distinct strategy to target helper T cells; a high affinity interaction with CD134 (

38 Recent reports suggest helper T-cell abnormalities in minimal-change nephrotic

39 of their antigen receptor (TCR) by B cells, helper T cells act on B cells via CD40 ligand and secret

40 We describe distinct helper T cell activation and migration profiles along th

41 tipeptide vaccine (6MHP), designed to induce helper T cells against melanocytic and cancer-testis ant

42 rough liver-resident immunoregulatory CD4(+) helper T cells, alternatively activated macrophages, and

43 T-B zone interface and promote induction of helper T cell and antibody responses.

44 ecular interactions at the interface between helper T cells and antigen-presenting B cells govern the

45 as T(H)2, T(H)9, T(H)17, T(H)22, follicular helper T cells and CD28(null) T cells, as well as other

46 reased frequencies of tumor-infiltrating CD4 helper T cells and CD8 memory cytotoxic T cells.

47 ir differentiation into the T(H)17 subset of helper T cells and colitogenic potential, in a manner de

48 CD4+ helper T cells and cytotoxic CD8+ T cells are key player

49 hyperactive response of the T(H)17 subset of helper T cells and developed spontaneous IL-22-dependent

50 found a significant reduction in follicular helper T cells and germinal center B cells in these mice

51 nifestations and GATA2 deficiency, CD4+ CD3+ helper T cells and naive CD3+ CD4+ CD62L+ CD45RA+ helper

52 ed genes, increased the number of follicular helper T cells and plasmablasts in the spleen, and led t

53 We detected reduced relative numbers of helper T cells and reduced activation of B cells in DLB

54 ffector cells of the TH1 and TH17 subsets of helper T cells and the development of experimental autoi

55 is essential for the formation of follicular helper T cells and thus GCs, although whether IRF4 plays

56 ene expression specific to the TH2 subset of helper T cells and was important for the migration of TH

57 ting immune activation was assessed based on helper T-cell and regulatory T-cell activation in mice.

58 hances Ag-specific CD8(+) T cell, follicular helper T cell, and Ag-specific Ab responses.

59 mediated by CD4(+)CXCR5(+)PD-1(+) follicular helper T cells, and can suppress inflammation in autoimm

60 renal allograft rejection induced by memory helper T cells, and CD8 T cell depletion at the time of

61 ished bone marrow PCs, lymph node follicular helper T cells, and memory B cell proliferation.

62 regulatory T cells (Treg), exhausted CD4(+) helper T cells, and myeloid-derived suppressor cells (MD

63 acilitated antigen-specific interaction with helper T cells, and promoted antibody affinity maturatio

64 he generation of antigen-specific follicular helper T cells, antigen-specific GC B cells, and high-af

65 CD4 helper T cells are critical for proper immune cell homeo

66 echanisms that maintain lineage integrity of helper T cells are largely unknown.

67 roles in the differentiation and function of helper T cells are not well understood.

68 TH17 cells (interleukin-17 (IL-17)-producing helper T cells) are highly proinflammatory cells that ar

69 row-infiltrating OX40+ cytotoxic T cells and helper T cells, as well as decreased ICOS+ and 4-1BB+ na

70 unctional antibody responses, via follicular helper T cells, as well as on the roles of CD4(+) T cell

71 ity complex (MHC) class II-restricted CD4(+) helper T cells but are also a common feature of MHC clas

72 class II complexes and defective priming of helper T cells but not of cytotoxic T lymphocyte (CTL) r

73 bility (MHC) class II complexes to stimulate helper T cells, but the genetic and regulatory basis for

74 Alloreactive memory helper T cells can induce potent alloantibody responses

75 These include a defective interaction of helper T cells (CD4+) with B cells in germinal centers,

76 ded double-negative, but depleted follicular helper, T-cell compartments and impaired Fas-dependent a

77 Furthermore, we find an association between helper T cell content in thyroid tissue and a COMMD3/DNA

78 CD4(+) helper T cells contribute important functions to the imm

79 ggerated airway eosinophilia, release type 2 helper T cell cytokines and exhibit airway hyper-respons

80 findings demonstrate that individual type 17 helper T-cell cytokines can have proinflammatory or anti

81 Type 17 helper T-cell cytokines have been implicated in the path

82 y a reduced expression of both types 1 and 2 helper T-cell cytokines.

83 ia, yet the mechanism by which HIV-1 induces helper T-cell death has not been defined.

84 Treg-mediated suppression of host follicular helper T cell-dependent antibody production.

85 fibroblasts resulted in impaired follicular helper T cell differentiation and, consequently, in redu

86 ondary complications and a skewed follicular helper T-cell differentiation in defined monogenic immun

87 How MyD88 regulates helper T-cell differentiation remains largely unknown, h

88 iRNA down-regulation promotes acquisition of helper T cell effector functions by relaxing the repress

89 ller cells (consisting of cytotoxic T cells, helper T cells, effector B cells, and natural killer cel

90 us, targeted TGF-beta signalling blockade in helper T cells elicits an effective tissue-level cancer

91 ht zone phenotype (site of Ag and follicular helper T cell encounter) express much higher levels of G

92 Helper T-cell epitope dominance in human immunodeficienc

93 Using human cells, we identified eight helper T-cell epitopes in PE38, a portion of the bacteri

94 n processing and MHC protein binding for all helper T-cell epitopes of an antigen.

95 opment of innate-like T-cells and follicular helper T-cells, events that are known to require strong/

96 Here we found that the helper T cell fate was not fixed and that mature, antige

97 Despite this, circulating follicular helper T cells from CVID+AIC subjects exhibited aberrant

98 Our study highlights the critical role helper T cell function has in the elicitation of broadly

99 ulin class switching is due to deficient CD4 helper T cell function.

100 ter understanding of the mechanisms by which helper T cells function in the natural history of cholan

101 Follicular helper T cells, germinal center B cells, and autoantibod

102 Finally, in NSTEMI patients, helper T cells had a reduced ability in T-cell receptor-

103 which were implicated in Treg and follicular helper T cell homeostasis.

104 of key transcription factors in determining helper T cell identity.

105 t to the profiling of circulating follicular helper T cells implicated in systemic lupus erythematosu

106 phages, reminiscent of the licensing role of helper T cells in antiviral adaptive immunity.

107 anti-fungal responses of the TH17 subset of helper T cells in controlling infection with Candida alb

108 ut the differentiation of pathogenic type 17 helper T cells in experimental autoimmune uveoretinitis

109 that endogenous cells of the TH17 subset of helper T cells in lymphoid organs of naive mice 'prefere

110 ion, mature B cells interact with follicular helper T cells in specialized structures called germinal

111 on of germinal center B cells and follicular helper T cells in the draining lymph node and Ag-specifi

112 ed and presented by GC B cells to follicular helper T cells in the light zone.

113 accumulated as cells of the T(H)17 subset of helper T cells in the lungs.

114 for proper differentiation of types 1 and 2 helper T cells in vivo by restraining the expression and

115 r better showed greater maximum effector and helper T-cell increases, elevated antiviral and alloreac

116 Helper T cell induced plasma cells (PCs) that secrete cl

117 +) T cells and amplifying Th2 and follicular helper T cell induction.

118 Itch deficiency in the TH17 subset of helper T cells, innate lymphoid cells and gammadelta T c

119 The differentiation of helper T cells into effector subsets is critical to host

120 that drive the differentiation of human CD4+ helper T cells into TFH cells remain largely undefined.

121 ifferentiation of the TH1 and TFH subsets of helper T cells is not well understood.

122 induced expression of FcgammaRIIIa on CD4(+) helper T-cells is an important finding since these recep

123 g cells) and the inflammatory TH17 subset of helper T cells leads to the development of autoimmune an

124 A4, identifying neuropilin-1 (NRP1); and the helper T cell marker, CD4.

125 by key transcription factors, including the helper T cell master regulator ThPOK, which suppresses t

126 ell (Treg) subset that suppresses follicular helper T cell-mediated B cell responses in the germinal

127 essive interferon-gamma that directly limits helper T cell-mediated support of humoral immunity and d

128 and atopic dermatitis, which are both type 2 helper T-cell-mediated diseases.

129 hare common characteristics including type 2 helper-T-cell-mediated inflammation.

130 ry T cells and lymph node-derived follicular helper T cells of patients with CVID compared with those

131 nd of coreceptors through which signals from helper T cells or pathogen-associated molecular patterns

132 e differentiation and function of follicular helper T cells or that of other helper T cell subsets.

133 on (P = 0.007) and CD25 expression on CD4(+) helper T cells (P = 0.0003) in the activated cord blood

134 MSI-H was directly associated with Helper T-cells (p = 0.034) and M1 macrophages (p < 0.000

135 on factors do not neatly conform to a simple helper T-cell paradigm.

136 The IL-6/follicular helper T cell pathway is a potential therapeutic target

137 pt predominantly type 1 helper or follicular helper T cell phenotypes in response to bacterial or vir

138 CD4+ helper T cells play an essential role in protection agai

139 trates that CD28 persistence is required for helper T cell polarization in response to infection, des

140 ntributed to miRNA-dependent proinflammatory helper T-cell polarization.

141 )CXCR3(+) programmed death 1 (PD1)(hi)CD4(+) helper T cell population distinct from T(FH) cells and e

142 intenance and/or expansion of the follicular helper T cell population, although it was dispensable fo

143 nalysis we define an alpha4 nAChR expressing helper T-cell population (alpha4(+)CD3(+)CD4(+)) and sho

144 he resulting enlarged circulating follicular helper T-cell population from CVID+AIC subjects provided

145 icate allergic disorders that show a similar helper T-cell profile with Th2/Th17 predominance.

146 sulted in the post-thymic termination of the helper T cell program and the functional differentiation

147 itory circuit that stabilizes the follicular helper T cell program at least in part through the contr

148 generation of an autoreactive TH17 subset of helper T cells, prominently associated with autoimmune d

149 T(H)2 and follicular helper T/ex-follicular helper T cells promotes asthma by inhibiting Treg cells.

150 elper T lymphocyte proportions and low naive helper T cell proportions are associated with those most

151 d from the carrier protein were critical for helper T cell recognition.

152 Thus, the sites of helper T-cell recognition, the dominant epitopes, are ta

153 also discuss the role of mTOR in follicular helper T cells, regulatory T cells, and other T cell sub

154 rs experienced significant downregulation of helper T-cell-related (T(H)1, T(H)17, and T(H)22) mRNA e

155 nt for differentiation of the TH17 subset of helper T cells remain unclear.

156 Deer mice remain infected despite a helper T cell response that leads to high-titer neutrali

157 the proteins contribute most strongly to the helper T cell response, highlight specific weaknesses of

158 mice developed an exaggerated type 1 and 17 helper T-cell response, characterized by natural killer

159 erial burdens and changes in the host type 1 helper T-cell response.

160 in the lungs, associated with poor specific helper T-cell response.

161 MHC class II-restricted T cells and promote helper T cell responses.

162 and other diseases driven by an imbalance in helper T cell responses.

163 s in an impaired ability to stimulate CD4(+) helper T cell responses.

164 regions, suggesting that both cytotoxic and helper T-cell responses are important.

165 iew the current status of the flexibility of helper T-cell responses in relation to their genetic reg

166 mmunodeficiency viruses (FIV and HIV) target helper T cells selectively, and in doing so they induce

167 our findings suggest that the TH9 subset of helper T cells serves an important role in driving ulcer

168 rexate is an immunomodulator with effects on helper T-cell signaling in psoriasis.

169 what do terms like 'lineage commitment' and helper T-cell 'specification' mean in the early 21st cen

170 renal allograft rejection induced by memory helper T cells starting at day 4 after transplantation.

171 r T cells and naive CD3+ CD4+ CD62L+ CD45RA+ helper T cell subpopulation fractions were significantly

172 elper T cells (TFH cells) are the prototypic helper T cell subset specialized to enable B cells to fo

173 FOXP3-positive Treg cells are a critical helper T cell subset, and dysregulation of Treg generati

174 anti-tumor effects of a unique human CD4(+) helper T-cell subset that directly recognizes the cytopl

175 ve phenotypes that mirror those of polarized helper T cell subsets in their expression of core transc

176 n RA compared to healthy controls, but other helper T cell subsets were not different.

177 The differentiation of CD4(+) helper T cell subsets with diverse effector functions is

178 e Notch family direct the differentiation of helper T cell subsets, but their influence on regulatory

179 ell progenitors to terminally differentiated helper T cell subsets.

180 f follicular helper T cells or that of other helper T cell subsets.

181 ls, even as they differentiate into effector helper T cell subsets.

182 ously defined 'master regulators' for CD4(+) helper T-cell subsets are also shared by ILC subsets.

183 t and functional divergence of the different helper T-cell subsets as well as in regulatory T cells.

184 ur appreciation for the actual complexity of helper T-cell subsets continues unabated.

185 We analyzed CD4(+) helper T-cell subsets from peripheral blood or cerebrosp

186 Added to the crowded scene for helper T-cell subsets is the continuously growing family

187 an important regulator of other specialized helper T-cell subsets within germinal centers, pre-germi

188 ferentiation of naive CD4 T lymphocytes into helper T cells subtypes, including types 1, 2, and 17 he

189 lammatory diseases thought to be mediated by helper T-cell subtypes 1 and 2 (TH1 and TH2), respective

190 nteresting results include CSF enrichment of helper T cells (subtypes TH1 and TH17) and regulatory T

191 ntiated more readily into cytokine-producing helper T cells, suggesting that activation-induced miRNA

192 A follicular helper T cell (T(FH) cell)-like profile characterized HI

193 hought be an autocrine factor for follicular helper T cell (T(FH)) and Th17 differentiation.

194 umulating evidence has shown that follicular helper T cell (T(FH)), a critical player in humoral immu

195 d T(reg) cell-mediated suppression of type 1 helper T cell (T(H)1 cell) responses and protected again

196 iota-dependent interleukin (IL)-17-producing helper T cell (T(H)17 cell) and immunoglobulin A respons

197 CD4(+) follicular helper T cells (T(FH) cells) are essential for germinal

198 Follicular helper T cells (T(FH) cells) are responsible for effecti

199 Follicular helper T cells (T(FH) cells) are specialized effector CD

200 Follicular helper T cells (T(FH) cells) have long been implicated i

201 paralleled by the accumulation of follicular helper T cells (T(FH) cells) is linked to mutation of th

202 Follicular helper T cells (T(FH) cells) provide critical help to B

203 ediated by CD4(+)CXCR5(+)Foxp3(-) follicular helper T cells (T(FH) cells).

204 cells suppressed CD4 T cells and follicular helper T cells (T(FH)) in a perforin-dependent manner du

205 Interleukin 17-producing helper T cells (T(H)17 cells) have a major role in prote

206 Interleukin-17 (IL-17)-producing helper T cells (T(H)17 cells) promote inflammation throu

207 Given their functional relatedness to type 2 helper T cells (T(H)2 cells), we explored whether Gfi1 a

208 t the presence of pathogenic effector type 2 helper T cells (T(H)2) in asthmatic lungs and find evide

209 Amongst helper T cells, T(H)17 cells have prominent roles in aut

210 tches, such TH17 cells acquired a follicular helper T cell (TFH cell) phenotype and induced the devel

211 pe 1 helper T cell (TH1 cell) and follicular helper T cell (TFH cell) responses.

212 atory T cells (TFR cells) inhibit follicular helper T cell (TFH cell)-mediated antibody production.

213 In contrast, follicular helper T cell (TFH) effectors are generated after primin

214 le to identify a super-functional follicular helper T cell (Tfh)-like subpopulation in lupus-prone NZ

215 Follicular helper T cells (Tfh ) are located within germinal center

216 Follicular helper T cells (TFH cells) and follicular regulatory T c

217 Follicular helper T cells (TFH cells) are CD4(+) T cells specialize

218 Follicular helper T cells (Tfh cells) are required for T cell help

219 Follicular helper T cells (TFH cells) are the prototypic helper T c

220 Follicular helper T cells (TFH cells) compose a heterogeneous subse

221 g the developmental mechanisms of follicular helper T cells (TFH cells) in humans is relevant to the

222 Aberrant population expansion of follicular helper T cells (TFH cells) occurs in patients with lupus

223 Within the GC, FO helper T cells (TFH cells) provide a local source of BLy

224 cy virus (HIV), which persists in follicular helper T cells (TFH cells), and Epstein-Barr virus (EBV)

225 pends on interactions with CD4(+) follicular helper T cells (TFH cells).

226 fuels the stepwise development of follicular helper T cells (TFH cells).

227 g helper T cells (TH17 cells) and follicular helper T cells (TFH cells).

228 ected germinal center (GC) CD4(+) follicular helper T cells (Tfh) after combination antiretroviral th

229 is is dependent on CD4(+)CXCR5(+) follicular helper T cells (TFH) and inhibited by CD4(+)CXCR5(+)Foxp

230 Follicular helper T cells (Tfh) are essential for B cell production

231 CD4+ follicular helper T cells (Tfh) are essential for germinal center (

232 by the more recent definition of follicular helper T cells (Tfh) as the key T cell subset in B cell

233 In follicular lymphoma (FL), follicular helper T cells (TFH) have been depicted as one of the ma

234 Follicular helper T cells (Tfh) have been well documented to play a

235 Follicular helper T cells (Tfh) play critical roles instructing, an

236 ty and gene connectivity in human follicular helper T cells (TFH), a cell type required for anti-nucl

237 Follicular helper T cells (Tfh), CD4 lymphocytes critical for effic

238 esponse through interactions with follicular helper T cells (TFH).

239 Follicular helper T cells (TFHs) are a key component of adaptive im

240 ssion also expanded the number of follicular helper T cells (TFHs) in a cell-intrinsic and Ag-specifi

241 the normal balance of pneumococcal-specific helper T cell (Th) 1/Th17 immunity to colonization, resu

242 n model on the mouse, and detect whether the helper T cells (Th) and regulatory T cells (Treg) could

243 -based vaccine formulation enhances systemic helper T cells TH1 and TH2 serum antibody and cytotoxic

244 Treg cell stability to repression of type 1 helper T cell (TH1 cell) and follicular helper T cell (T

245 between groups were observed for the type 1 helper T cell (TH1)-associated chemokines CXCL9 and CXCL

246 uding Slc2a1, Slc2a3, Pkm and Hk2, in type 1 helper T cells (TH1 cells) exposed to low concentrations

247 r the signaling pathways of type 1, 2 and 17 helper T cells (TH1, TH2 and TH17), JAK-STAT, interferon

248 naling, induces the expression of the type 1 helper T-cell (Th1) cytokine, interferon gamma, and supp

249 Vaccination induced type 1 helper T-cell (Th1)-biased CD4 T-cell responses and low

250 ne networks in the intestine associated with helper T cells' (Th1, Th2, and Th17) specific pathways.

251 negative Borrelia cultures, and the type 17 helper T cell (TH17)-associated cytokine interleukin 23

252 Interleukin 17 (IL-17)-producing helper T cells (TH17 cells) and CD4(+) inducible regulat

253 ntiation of interleukin 17 (IL-17)-producing helper T cells (TH17 cells) and follicular helper T cell

254 Interleukin (IL) 17-secreting CD4(+) helper T cells (Th17 cells) are essential for host defen

255 tion of interleukin (IL)-17-producing CD4(+) helper T cells (TH17 cells) has a pivotal role in autoim

256 mediated by interleukin 17 (IL-17)-producing helper T cells (TH17 cells) in the peripheral immune and

257 IL-17-producing CD4 helper T cells (Th17 cells) play a critical role in prom

258 recently discovered interleukin-17 producing helper T cells (Th17), which are fundamental for anti-mi

259 al specimens reveals a predominantly type 17 helper T-cell (Th17)/Th1 signature, implicating this as

260 A-regulated pathways that control the type 2 helper T cell (TH2 cell) responses that drive pathogenic

261 Multiple exposure to type 2 helper T cell (Th2)-inducing stimuli further enhances bo

262 The role of the type 2 helper T cell (Th2)-polarizing cytokines IL-4 and IL-10

263 ated inflammation that is driven by a type 2 helper T cell (Th2).

264 ate lymphoid cells (ILC2s) and CD4(+) type 2 helper T cells (TH2 cells) are defined by their similar

265 p 2 innate lymphoid cells (ILC2s) and type 2 helper T cells (Th2 cells) are the primary source of int

266 interleukin-33 (IL-33), which induces type-2 helper T cells (Th2 cells) at the site of infection to p

267 Type 2 helper T cells (TH2 cells) produce interleukin 13 (IL-13

268 lymphoid cells (ILC2s) and recruited type 2 helper T cells (TH2 cells).

269 with increased levels of eotaxins and type 2 helper T-cell (Th2) cytokines as disease progressed and

270 Effects on various type 2 helper T-cell (Th2)-associated biomarkers and safety and

271 by dupilumab of these key drivers of type 2 helper T-cell (Th2)-mediated inflammation could help in

272 the differentiation of CD4(+) IL-9-producing helper T cells (TH9 cells) remain incompletely understoo

273 cells to differentiate into pro-inflammatory helper T cells that are prone to invade into tissue and

274 cells, promoting their differentiation into helper T cells that coordinate immune responses.

275 ility complex (MHC) class II-selected CD4(+) helper T cells that expressed CD8-lineage genes such as

276 dependent skin inflammation driven by CD4(+) helper T cells that produced the cytokines IL-17 and IL-

277 cells subtypes, including types 1, 2, and 17 helper T cells, that have more tailored immunologic resp

278 Unlike other helper T cells, the costimulatory ligands responsible fo

279 ate that they are not equivalent for CD4(+) 'helper' T cells, the principal orchestrators of adaptive

280 atory disease driven by the T(H)17 subset of helper T cells through molecular mechanisms that remain

281 ulates differentiation of the TH17 subset of helper T cells, thymic T cell development and lymph-node

282 The discovery of the specification of CD4(+) helper T cells to discrete effector 'lineages' represent

283 the expression of genes in the TH2 subset of helper T cells to enhancer occupancy by the BATF-IRF4 tr

284 In multimarker analysis, the helper T cell type 1 (TH1)-related markers interferon-ga

285 IL-13, a helper T cell type 2 (Th2) cytokine, transforms cultured

286 L-5 circumsporozoite protein (CSP) ratios, a helper T cell type 2 cytokine, correlated with higher od

287 s, highlighting the underappreciated role of helper T-cell type 2-related pathways.

288 t mRNA level ratio, consistent with a type 2 helper T-cell-type inflammatory response, and subacute f

289 modes of antigen presentation and priming of helper T cell versus CTL responses.

290 292, enhancing T-cell activation, in NSTEMI helper T cells versus SA and controls (each, p < 0.001),

291 ogate endogenous, Salmonella-specific CD4(+) helper T cells, we show that certain host microenvironme

292 These tonsillar CCR6(+)B helper T cells were phenotypically distinct from follicu

293 Follicular helper T cells were the primary source of IL-21 that inh

294 er ICOS(+) populations, including peripheral helper T cells, were highly sensitive to costimulation b

295 ibodies require help from other lymphocytes (helper T cells) which recognize small peptides derived f

296 ncrease in numbers of circulating follicular helper T cells, which correlated with decreased regulato

297 F) gene (Batf(-/-)) lack TH17 and follicular helper T cells, which demonstrates that Batf is a transc

298 haracterized population of extrafollicular B helper T cells, which produced IL-10 and could play a pr

299 ls and CD4(+) Th cells, including follicular helper T cells, which resulted in high titers of anti-nu

300 103(+) DC subsets induced the TH17 subset of helper T cells, while CD103(-)Sirpalpha(+) DCs induced t

301 thogen containment to the differentiation of helper T cells, yet the cues that position cells in this