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1 evelop from MPP2, a myeloid-biased subset of hematopoietic progenitors.
2 enhanced human erythroid differentiation of hematopoietic progenitors.
3 filtration of the bone marrow by transformed hematopoietic progenitors.
4 e enriched in NKT progenitors, like in other hematopoietic progenitors.
5 es the ex vivo characterization of zebrafish hematopoietic progenitors.
6 HPs transcriptionally resemble native Kit(+) hematopoietic progenitors.
7 oform of SON enhances replating potential of hematopoietic progenitors.
8 also revealed a prethymic role for BCL11B in hematopoietic progenitors.
9 -BP1) and 4E-BP2 as compared with most other hematopoietic progenitors.
10 t least 10(1)(3)-fold) expansion of immature hematopoietic progenitors.
11 ecreased expression of multiple Hox genes in hematopoietic progenitors.
12 and disrupts cis-regulatory architecture of hematopoietic progenitors.
13 ted in both CD11b + and CD11b- cells, and in hematopoietic progenitors.
14 s proliferation of embryonic fibroblasts and hematopoietic progenitors.
15 erate with GATA1s in transformation of fetal hematopoietic progenitors.
16 e expression of ETO and RUNX1 genes in human hematopoietic progenitors.
17 immune lineages and are accessible in common hematopoietic progenitors.
18 ythroid-specific genes within populations of hematopoietic progenitors.
19 tem cells (HSCs) and other lineage-committed hematopoietic progenitors.
20 the in vitro differentiation of iPSC toward hematopoietic progenitors.
21 lineages and colony-forming unit assays for hematopoietic progenitors.
22 er HSC re-entry into quiescence, contrary to hematopoietic progenitors.
23 nervous system (SNS) regulates neuronal and hematopoietic progenitors.
24 alternative for studying telomere crisis in hematopoietic progenitors.
25 ty of mast cells to differentiate from their hematopoietic progenitors.
26 ical pathways and in accessible chromatin of hematopoietic progenitors.
27 odor environments fail to sustain a pool of hematopoietic progenitors.
28 ) and mouse bone marrow cells, which contain hematopoietic progenitors.
29 ile promoting the self-renewal of very early hematopoietic progenitors.
30 Macrophages derive from multiple sources of hematopoietic progenitors.
31 hemogenic endothelium (HE), and multipotent hematopoietic progenitors.
32 am progenitors, including HE and multipotent hematopoietic progenitors.
33 the rarity and heterogeneity of the affected hematopoietic progenitors.
34 cessary to maintain many c-kit(+)-restricted hematopoietic progenitors.
35 ubtypes of acute leukemia, but not in normal hematopoietic progenitors.
36 ction to enforce self-renewal in bone marrow hematopoietic progenitors.
37 ccessfully engrafted and differentiated into hematopoietic progenitors.
38 ediated crosstalk between marrow B cells and hematopoietic progenitors.
39 udied erythropoiesis using knockout mice and hematopoietic progenitors.
40 y in the absence of PRC1, to fully transform hematopoietic progenitors.
41 ommitment were mediated by beta3 integrin on hematopoietic progenitors.
42 promote monocyte/macrophage development from hematopoietic progenitors, a process critical in trigger
43 spheres can significantly expand multipotent hematopoietic progenitors able to engraft immunodeficien
44 B cells into IFrag(-/-) mice protects early hematopoietic progenitor activity during systemic respon
45 iver exhibited severe deficiency in HSCs and hematopoietic progenitors, along with elevated reactive
46 o such effects were observed in CD34+ normal hematopoietic progenitors, although CDK6 was efficiently
47 iota is known to influence the generation of hematopoietic progenitors, although the pathways underly
48 scontinuous sinusoids also allow circulating hematopoietic progenitor and stem cells to populate the
49 with a median of 37.5% (range 12.6-76.4%) in hematopoietic progenitors and a vector copy number per c
50 potent stem (iPS) cell reprogramming of aged hematopoietic progenitors and allowed the resulting aged
52 hat express a hyperactive mutant of Stat5 in hematopoietic progenitors and derived lineages in a liga
53 rophages are derived from primitive yolk-sac hematopoietic progenitors and exhibit hallmarks of M2 ac
54 ia (MLL) trigger aberrant gene expression in hematopoietic progenitors and give rise to an aggressive
55 K2), showed a suppressive effect of HMGB1 on hematopoietic progenitors and increase in long-term cult
57 L-RARA mice, which express PML-RARA in early hematopoietic progenitors and myeloid precursors, with o
58 CD21 promoter enabled Xlf deletion in early hematopoietic progenitors and splenic mature B cells, re
60 ells was shown by the acquired resistance of hematopoietic progenitors and T lymphocytes to DNA cross
61 vites evolutionary parallels with vertebrate hematopoietic progenitors and the independent myeloid sy
62 nt by preserving immune resources, including hematopoietic progenitors and thymic activity, which cou
63 protein synthesis in HSCs, but not in other hematopoietic progenitors, and impaired their reconstitu
64 matopoietic engraftment and clonogenicity of hematopoietic progenitors, and is dependent on secreted
65 ression, enhanced self-renewal, expansion of hematopoietic progenitors, and myeloid differentiation b
66 deletion of Chd1 leads to loss of definitive hematopoietic progenitors, anemia, and lethality by embr
69 ence with expansion and differentiation into hematopoietic progenitors are incompletely understood.
72 oughout adult life, macrophages derived from hematopoietic progenitors are seeded throughout the body
74 plerixafor results in rapid mobilization of hematopoietic progenitors, but fails to mobilize 33% of
76 Applying treeHFM to time lapse images of hematopoietic progenitor cell differentiation, we demons
77 by which that occurs, using an immortalized hematopoietic progenitor cell line, EML-C1, as a model s
78 igratory responses of cocultured stromal and hematopoietic progenitor cell lines, helping explain how
79 on of hematopoietic stem cells and decreases hematopoietic progenitor cell numbers both in vivo and i
80 ability in hematopoietic stem cell (HSC) and hematopoietic progenitor cell populations from young and
81 Somatic mutations were tracked to CD34(+) hematopoietic progenitor cell populations, being further
82 ug sensitivity, and abrogated MPP1-dependent hematopoietic progenitor cell replating in methylcellulo
83 s of thrombotic microangiopathy secondary to hematopoietic progenitor cell transplantation, infection
84 ith significantly increased numbers of HSCs, hematopoietic progenitor cell-1 (HPC-1), HPC-2, and Lin(
87 report that inhibition of Notch signaling in hematopoietic progenitor cells (HPC), myeloid-derived su
89 oiesis characterized by increased numbers of hematopoietic progenitor cells (HPCs) at the expense of
90 , and narciclasine induced more lethality in hematopoietic progenitor cells (HPCs) expressing germlin
91 fety and effectiveness of mobilizing CD34(+) hematopoietic progenitor cells (HPCs) in adults with bet
93 d CD34(+)CXCR4(+) cells as well as assayable hematopoietic progenitor cells (HPCs) irrespective of th
94 rus (HCMV) can establish latent infection in hematopoietic progenitor cells (HPCs) or CD14 (+) monocy
95 nduce myelosuppression of uninfected CD34(+) hematopoietic progenitor cells (HPCs) through an increas
96 Here we show that murine HSCs and committed hematopoietic progenitor cells (HPCs) undergo a gradual,
97 (HSCs), impaired radioprotective function of hematopoietic progenitor cells (HPCs), and myeloid and e
98 determine the effect of fibrosis on healthy hematopoietic progenitor cells (HPCs), bioartificial mat
99 t5 deletion resulted in a concurrent loss of hematopoietic progenitor cells (HPCs), leading to fatal
100 d lung homing of bone marrow-derived CD34(+) hematopoietic progenitor cells (HPCs), which include eos
101 c stem cells (HSCs) generate highly dividing hematopoietic progenitor cells (HPCs), which produce all
108 transcriptomic profiling of normal human HSC/hematopoietic progenitor cells [HPCs], revealing that se
110 iferation and appropriate differentiation of hematopoietic progenitor cells and in animal hematopoies
111 tein that confers self-renewal capability to hematopoietic progenitor cells and induces acute myeloge
112 ga-dose" of T cell-depleted peripheral blood hematopoietic progenitor cells and no posttransplant pha
113 ed-forward loop between inflammation-adapted hematopoietic progenitor cells and the inflammatory diso
114 patient can be induced to differentiate into hematopoietic progenitor cells and then further to eryth
115 ired for latency and reactivation in CD34(+) hematopoietic progenitor cells and virion maturation in
116 The findings indicate that Th2-promoting hematopoietic progenitor cells are rapidly recruited to
117 wth factor A (Vegf-a)-dependent apoptosis of hematopoietic progenitor cells associated with overprodu
118 ytomegalovirus (HCMV) enters primary CD34(+) hematopoietic progenitor cells by macropinocytosis, wher
119 opoiesis and changes in pre-mRNA splicing in hematopoietic progenitor cells by whole transcriptome an
121 Recent studies have found that peripheral hematopoietic progenitor cells contribute to type 2 cyto
122 n attenuated strain of CMV are maintained in hematopoietic progenitor cells during their differentiat
123 reviously shown that HCMV infection of human hematopoietic progenitor cells engrafted in immune defic
125 tropenias and for mobilization of peripheral hematopoietic progenitor cells for stem cell transplanta
126 ultured from peripheral blood or bone marrow hematopoietic progenitor cells from four patients were u
127 BM) chimeras were generated by transplanting hematopoietic progenitor cells from stress-susceptible m
129 tly used to stimulate bone marrow release of hematopoietic progenitor cells in preparation for stem c
130 hich a low ROS level is required to maintain hematopoietic progenitor cells in the tissue and to redu
131 tivity promotes the generation of MDSCs from hematopoietic progenitor cells in vitro, demonstrating a
132 ed that HCMV enters into the primary CD34(+) hematopoietic progenitor cells in which it establishes l
133 CCR9 controls the immigration of multipotent hematopoietic progenitor cells into the thymus to sustai
134 skewing promote oncogenic transformation of hematopoietic progenitor cells into therapy-resistant le
138 ients with systemic histiocytoses resides in hematopoietic progenitor cells prior to committed monocy
139 tion here of HCMV entry into primary CD34(+) hematopoietic progenitor cells through macropinocytosis
141 elogenous leukemia (CML) caused normal mouse hematopoietic progenitor cells to divide more readily, a
142 the mechanisms that govern the adaptation of hematopoietic progenitor cells to inflammation and its s
145 , we examined the entry of HCMV into CD34(+) hematopoietic progenitor cells where the virus establish
146 y glycosyltransferases, and decorates marrow hematopoietic progenitor cells with alpha2,6-linked sial
147 f a human cell AML, generated in CD34+ human hematopoietic progenitor cells xenografted into immunoco
148 ic stem cells (HSCs), an increased number of hematopoietic progenitor cells, and an increased proport
149 thma, decreased B-lymphocyte development and hematopoietic progenitor cells, and lymphoid organ hypop
150 n, intermediate reactivity toward monocytes, hematopoietic progenitor cells, and T-cells was observed
151 is detected in hematopoietic stem cells and hematopoietic progenitor cells, and that its expression
152 cells, we transduced lineage-depleted murine hematopoietic progenitor cells, observing GFP expression
153 asia, fibrosis, and impaired colonization by hematopoietic progenitor cells, resulting in anemia and
154 of T-lineage specification in human CD34(+) hematopoietic progenitor cells, similar to ICN1 overexpr
155 Although both ligands activated Notch in hematopoietic progenitor cells, they had an opposite eff
156 em cells (HSCs) can result in high yields of hematopoietic progenitor cells, this generally occurs at
157 t-like or a replicative infection in CD34(+) hematopoietic progenitor cells, we defined classes of lo
158 ssion and ex vivo differentiation of CD34(+) hematopoietic progenitor cells, we demonstrate that C/EB
159 nant-negative ETS1 p27 isoform in cord blood hematopoietic progenitor cells, we show that the transcr
184 ding of RBCs, T cell numbers and activation, hematopoietic progenitor changes, and signaling kinetics
185 eukemia (AML) represents a clonal disease of hematopoietic progenitors characterized by acquired hete
186 this study, we test the assumption that the hematopoietic progenitor/colony-forming cells of the emb
188 ECs generated substantially more CD34+CD45+ hematopoietic progenitors compared with cells cocultured
189 find that deletion of Cebpa rendered murine hematopoietic progenitors completely resistant to MLL-EN
191 and KD of miR-486-5p in primary fetal liver hematopoietic progenitors demonstrated that miR-486-5p c
193 al-10 expression in human CD34(+) cord blood hematopoietic progenitors differentiated to eosinophils.
195 L cells, as CHD4 depletion in normal CD34(+) hematopoietic progenitors does not increase their suscep
198 wed the visualization and differentiation of hematopoietic progenitors ex vivo in real-time with time
199 the c-Kit receptor tyrosine kinase to elicit hematopoietic progenitor expansion but can be toxic when
200 tracking de novo transformation from normal hematopoietic progenitors expressing an acute myeloid le
203 imeric mice (Cdk5(+/+C) or Cdk5(-/-C)) using hematopoietic progenitors from either embryonic day 16.5
205 reviously demonstrated that the induction of hematopoietic progenitors from fibroblasts progresses th
206 gulation of SLPI in CD34(+) bone marrow (BM) hematopoietic progenitors from healthy individuals resul
207 omide-induced reprogramming was conserved in hematopoietic progenitors from individuals with sickle c
208 supporting B lymphopoiesis in vitro, whereas hematopoietic progenitors from mutant mice exhibit norma
209 ha-dependent inhibitory effects on malignant hematopoietic progenitors from patients with chronic mye
212 ng hematopoietic cells and bone marrow-based hematopoietic progenitors, functional evidence of the ce
214 found Cdc73 promotes expression of an early hematopoietic progenitor gene program that prevents diff
216 reases proliferation of these most primitive hematopoietic progenitors, giving rise to higher levels
217 nclear, and direct infection of intermediate hematopoietic progenitors has not been established as a
218 pyrimido-indole derivative UM171, to expand hematopoietic progenitors (HPs) derived from hPSCs in ch
220 ADAR1-induced hyper-editing in normal human hematopoietic progenitors impairs miR-26a maturation, wh
222 us to explore the effects of antibiotics on hematopoietic progenitors in detail using a murine model
223 Despite markedly reduced cellularity of hematopoietic progenitors in E18.5 bone marrow, the numb
224 st mature granulocytes, but not toward human hematopoietic progenitors in humanized immune reconstitu
225 irculation prevented CBLB502 from protecting hematopoietic progenitors in lethally irradiated mice, i
226 ated proliferation of adoptively transferred hematopoietic progenitors in the bone marrow of mice wit
227 ic tissue and the ability to clonally expand hematopoietic progenitors in vitro has provided fundamen
231 treatment with TNF-alpha of lineage-negative hematopoietic progenitors increased NK and myeloid diffe
232 n murine models, forced expression of MN1 in hematopoietic progenitors induces an aggressive myeloid
233 oid leukemia, mutated cells transform normal hematopoietic progenitors into "leukemic like" cells thr
234 olute a mixture of ES cells, fibroblasts and hematopoietic progenitors into high-quality chromatin st
235 normal gene expression networks to reprogram hematopoietic progenitors into preleukemic stem cells, a
237 ed with BCR-ABL1-positive ALL, a multipotent hematopoietic progenitor is affected by the BCR-ABL1 fus
238 standing how CMV interacts with LC and their hematopoietic progenitors is thus essential to develop i
241 p1 constitutively co-immunoprecipitated with hematopoietic progenitor kinase 1 (HPK1) in neutrophil-l
243 itment of the inhibitory signaling molecules hematopoietic progenitor kinase 1 and SH2-containing ino
246 rogenitor cells expressing SMC, myeloid, and hematopoietic progenitor-like properties and that differ
247 nt macrophages originate from both embryonic hematopoietic progenitors located within the yolk sac an
248 known to function as a positive regulator of hematopoietic progenitor maintenance in the lymph gland
249 cuit that controls quiescence of MB-HSCs and hematopoietic progenitors marked by histidine decarboxyl
251 GATA1 suppression in ES and iPS cell-derived hematopoietic progenitors may enhance megakaryocyte prod
252 in the transcriptional states of developing hematopoietic progenitors may generally shape the mutati
253 proliferation and blocked differentiation of hematopoietic progenitors mediated, in part, by altered
254 sed by HSCs, and at lower levels by c-kit(+) hematopoietic progenitors, megakaryocytes, and Leptin Re
257 atopoietic stem cells (HSCs) and multipotent hematopoietic progenitors (MPPs) are routinely isolated
258 e between proliferation and growth arrest in hematopoietic progenitors, myeloid lineage specific dele
264 is SCF variant elicited biased activation of hematopoietic progenitors over mast cells in vitro and i
266 consist of G-CSF-dependent shifts of marrow hematopoietic progenitor populations including expansion
267 e, we sequenced RNA from eight primary human hematopoietic progenitor populations representing the ma
269 TACs would spare a high proportion of normal hematopoietic progenitors, preventing the neutropenia in
272 nitial activation of the Gata1 gene in early hematopoietic progenitors remains to be elucidated.
274 d, consistent with a deficiency of primitive hematopoietic progenitors, serum levels of the hematopoi
275 for occluding-junctions in regulating niche-hematopoietic progenitor signalling and link this mechan
276 ilencing PAPD5-mediated oligoadenylation, on hematopoietic progenitor specification and function in D
277 tor ARID3a is expressed in a subset of human hematopoietic progenitor stem cells in both healthy indi
279 Recently, ST2 expression was described on hematopoietic progenitor subsets, where its function rem
280 uced beta1- and beta2-integrin expression on hematopoietic progenitors suggests that increased spleni
281 ization of the thymus by bone-marrow-derived hematopoietic progenitors that migrate through the blood
282 al profiling of bone marrow lineage negative hematopoietic progenitors that recovers a key missing br
283 ays an important role in the niche to expand hematopoietic progenitors through the modulation of seve
284 udied, the differentiation trajectories from hematopoietic progenitors to basophils and mast cells ar
285 Hypercholesterolemia acts in platelets and hematopoietic progenitors to exacerbate thrombosis and a
286 pectedly, Cdk6 R31C impairs the potential of hematopoietic progenitors to repopulate upon adoptive tr
287 are cytokines, which regulate commitment of hematopoietic progenitors to the different blood lineage
288 (EndoMT) and the recruitment of circulating hematopoietic progenitors to the heart have been reporte
289 in vivo by creating bone marrow chimera from hematopoietic progenitors transduced with an inducible s
290 hat Il7r-deficient, but not wild-type, mouse hematopoietic progenitors transduced with constitutively
291 gnaling does not alter gene expression until hematopoietic progenitors transition from fetal to adult
292 ts lineage choice in differentiating primary hematopoietic progenitors using image patches from brigh
296 h-risk LCH arises from somatic mutation of a hematopoietic progenitor, whereas low-risk disease arise
297 omparison with T cells generated from HE and hematopoietic progenitors, which could only be expanded
298 ensing dependence through RagA and mTORC1 in hematopoietic progenitors, which dynamically drive matur
299 n in a bone marrow (BM)-resident multipotent hematopoietic progenitor, while low-risk, MS-RO- and sin