ライフサイエンスコーパス: heme oxygenase-1

1 + monocytes expressed higher basal levels of heme oxygenase-1.

2 cyte anti-inflammatory heme-degrading enzyme heme oxygenase-1.

3 er two important molecules: nitric oxide and heme oxygenase-1.

4 f pathogenic CD8(+) T cells and induction of heme oxygenase-1.

5 n, the release of heme, and the induction of heme oxygenase-1.

6 l abrogated by pharmacological inhibition of heme oxygenase-1.

7 d on increased expression of the Nrf2 target heme oxygenase-1.

8 anced expression of glucose transporters and heme oxygenase-1.

9 nitric oxide synthase, cyclooxygenase-2, and heme oxygenase-1.

10 ement of NF-erythroid 2-related factor 2 and heme oxygenase-1.

11 p-regulation of the stress-inducible protein heme-oxygenase-1.

12 f Bcl-2 (5.5-folds), Bcl-xl (5.5-folds), and heme oxygenase-1 (4.4-folds); decreased expression of IC

13 ) mice have increased expression/activity of heme oxygenase-1, a phase II antioxidant, and NF (erythr

14 RSG-mediated transcriptional upregulation of heme oxygenase-1, a PPARgamma target gene.

15 kers Kim-1, p21, and the cytoprotective gene heme oxygenase-1 accompanied this.

16 The carboxyhemoglobin level (a measure of heme oxygenase 1 activity) has not been assessed in adul

17 Heme oxygenase 1, an enzyme upregulated by oxidative str

18 aimed to investigate the mechanisms by which heme oxygenase-1, an anti-inflammatory enzyme, is protec

19 , despite significantly higher expression of heme oxygenase-1, an antioxidant and cytoprotective enzy

20 miR-24 also regulated heme oxygenase 1 and H2A histone family, member X, in vi

21 orresponded with increases in cytoprotective heme oxygenase 1 and IL-10 mRNAs, selective reductions i

22 ential for linked antioxidant protection via heme oxygenase 1 and reduced foam cell formation via liv

23 ranofin displayed synergistic lethality with heme oxygenase-1 and glutamate-cysteine ligase inhibitor

24 via Nrf2 pathway, enhancing GSH/GSSG ratio, heme oxygenase-1 and glyoxalase 1 in liver tissue.

25 e discuss here new insights into the role of heme oxygenase-1 and heme on cardiovascular health, and

26 ontractility rather than passive stretch via heme oxygenase-1 and histone deacetylase signalling.

27 lls and up-regulated anti-inflammatory genes heme oxygenase-1 and IL-10.

28 d4 to Nrf2-binding sites on the promoters of heme oxygenase-1 and NADPH quinone oxidoreductase 1.

29 rf2 or DJ-1 attenuated Cu((II))ATSM-mediated heme oxygenase-1 and NADPH quinone oxidoreductase-1 indu

30 into the nucleus to induce transcription of heme oxygenase-1 and other cytoprotective enzymes throug

31 and reendothelialization via upregulation of heme oxygenase-1 and SDF-1alpha.

32 result of the upregulation of cytoprotective heme oxygenase-1 and sirtuin-1 (SIRT1).

33 )S increased the expression of antioxidants (heme oxygenase-1 and thioredoxin 1), increased the expre

34 Human heme oxygenases 1 and 2 (HO-1 and HO-2) degrade heme in

35 reverses vitamin C-induced up-regulation of heme-oxygenase-1 and ferritin in KRAS-mutant cancer cell

36 ples for hypoxia-inducible factor 1alpha and heme oxygenase 1, and 4) immunohistochemistry of hippoca

37 ntioxidant systems such as peroxiredoxins-1, heme oxygenase-1, and anti-apoptotic factors, including

38 ed anti-inflammatory factors interleukin-10, heme oxygenase-1, and Hsp70 in macrophages stimulated or

39 ing IL-1ra, IL-10, and PGE(2), but not IL-6, heme oxygenase-1, and NO, attenuated 5-FU-MSC-induced im

40 II, chemokine (C-C motif) ligand 22 (CCL22), heme oxygenase-1, and TSG6.

41 lation of the oxidative stress response gene heme oxygenase-1, and we demonstrated that NF-kappaB inh

42 evated levels of TNFalpha, reduced levels of heme-oxygenase-1, and display apparent signs of oxidativ

43 Mitochondrial accumulation of heme oxygenase-1, another heme protein, was also regulat

44 arkable cardioprotective effects ascribed to heme oxygenase-1 are best evidenced by its ability to re

45 We also show data to implicate heme oxygenase-1 as a potential molecular link between N

46 le to upregulate the atheroprotective enzyme heme oxygenase-1 at the RNA and protein level in respons

47 ntrol animals, and inhibiting the HIF target heme-oxygenase-1 before IR reduced GFR in STN animals.

48 nhancing expression of the IL-10 target gene heme oxygenase-1 by mechanisms dependent on p38 MAPK act

49 lial NOS (eNOS), Nrf2, and Phase II enzymes (heme oxygenase-1, catalase, superoxide dismutase-1) in a

50 issue was taken to determine lung damage and heme oxygenase-1 concentration and activity.

51 -1beta and FAS concentrations, and increased heme oxygenase-1 concentration.

52 H(2)O(2), concomitant with up-regulation of heme oxygenase 1, COX-2, and anti-apoptotic proteins (BC

53 Macrophages from heme oxygenase-1 deficient mice (Hmox1(-/-)) had increas

54 enhances its paracine effects on RIII via a heme oxygenase-1 dependent mechanism, which may help us

55 a, IL-1beta and nitric oxide partially via a heme oxygenase-1 dependent mechanism.

56 s, whereas treatment with carbon monoxide, a heme oxygenase-1 enzymatic product, abrogated this effec

57 als treated with tin protoporphyrin (SnPP, a heme oxygenase-1 enzyme inhibitor), even after Ad.Trx1 t

58 Heme oxygenase 1 expression is increased in pediatric pa

59 ion, hypoxia-inducible factor 1alpha-induced heme oxygenase 1 expression resulting in improved surviv

60 with the latter associated with induction of heme oxygenase 1 expression.

61 at abrogated the Nrf2-dependent induction of heme oxygenase-1 expression by nitro-oleic acid.

62 fects; JunB activated whereas JunD repressed heme oxygenase-1 expression in human renal epithelial ce

63 -induced oxidative stress by down-regulating heme oxygenase-1 expression via nuclear factor (erythroi

64 nd molecular markers (caspase-3 activity and heme oxygenase-1 expression) were analyzed.

65 Tin protoporphyrin IX did not affect heme oxygenase-1 expression, but heme oxygenase activity

66 ac Akt phosphorylation and further increased heme oxygenase-1 expression.

67 ncreased inducible nitric oxide synthase and heme-oxygenase 1 expression, and increased MDA and plasm

68 ncreased inducible nitric oxide synthase and heme-oxygenase 1 expression, and increased plasma creati

69 e and iron in liver despite up-regulation of heme oxygenase 1, ferroportin, and ferritins.

70 ation of the CBS inhibitor, CO, a product of heme oxygenase-1, flip the operating preference of CSE f

71 athione S-transferase (GST) genes as well as heme oxygenase 1 gene (HMOX1) encode enzymes that detoxi

72 med a systematic review and meta-analysis of heme oxygenase 1 gene (HO-1) promoter polymorphisms and

73 nosine thymidine dinucleotide repeats in the heme oxygenase-1 gene promoter in 386 patients with coro

74 nosine thymidine dinucleotide repeats in the heme oxygenase-1 gene promoter is associated with cardio

75 nosine thymidine dinucleotide repeats in the heme oxygenase-1 gene promoter is associated with higher

76 Heme oxygenase-1 (gene HMOX1; protein HO-1) is the induc

77 expression of Nrf2-dependent genes, such as heme oxygenase-1, glutamate-cysteine ligase catalytic su

78 Heme oxygenase-1 has been implicated in regulating DC ma

79 f the azide complex of substrate-bound human heme oxygenase 1 (hHO) has been investigated by (1)H NMR

80 Human heme oxygenase-1 (hHO-1) catalyzes the O2- and NADPH-dep

81 adenoassociated virus (rAAV)-encoding human heme oxygenase-1 (hHO-1) in attenuating post-ischemic in

82 In humans, heme oxygenase-1 (hHO-1) is overexpressed in tumor tissu

83 the CX3CR1 receptor induced upregulation of heme-oxygenase-1 (HMOX-1), an antioxidant and anti-infla

84 talase, glutathione peroxidase 1 (GPX1), and heme oxygenase 1 (Hmox1) and transcription factor nuclea

85 sapje-like, while upregulating the inducible heme oxygenase 1 (Hmox1) at the protein level.

86 We showed that variation in basal levels of heme oxygenase 1 (HMOX1) contribute to the response to O

87 ed reduced progesterone levels and placental heme oxygenase 1 (Hmox1) expression and increased methyl

88 translocate into the nucleus and up-regulate heme oxygenase 1 (HMOX1) gene expression.

89 nscriptional repressor, negatively regulates heme oxygenase 1 (HMOX1), a key cytoprotective enzyme th

90 h regulates the expression of genes encoding heme oxygenase 1 (Hmox1), glutamate-cysteine ligase cata

91 ous Nrf2-regulated genes/proteins, including heme oxygenase 1 (Hmox1).

92 We hypothesized that heme oxygenase 1 (HMOX1; HO-1), an enzyme responsible fo

93 o prevent accumulation, the inducible enzyme heme oxygenase-1 (HMOX1) catalyzes degradation of heme.

94 n (HP), cluster of differentiation (CD) 163, heme oxygenase-1 (HMOX1), and biliverdin reductase A (BL

95 Inactivation of heme oxygenase-1 (Hmox1), one of the most stringently de

96 genes increased in the DKO liver, including heme oxygenase-1 (Hmox1), which disrupts complex III and

97 otective response relies on the induction of heme oxygenase-1 (HMOX1; HO-1) and ferritin H chain (FTH

98 em macrophages through coregulation of HO-1 (heme oxygenase-1; HMOX1) and lipid homeostasis genes.

99 ctivated protein (MAP) kinase, expression of heme oxygenase 1 (HO-1) and cyclooxygenase 2 (COX-2), an

100 ession of heat-shock protein 70 (HSP-70) and heme oxygenase 1 (HO-1) and promoted cell survival after

101 nd up-regulation of the antioxidant proteins heme oxygenase 1 (HO-1) and sulfiredoxin 1 (SRXN1).

102 Heme oxygenase 1 (HO-1) and the cytochromes P450 (P450s)

103 re increases the stability of mRNAs encoding heme oxygenase 1 (HO-1) and TIEG-1 in human and mouse fi

104 D2) expression and a delayed upregulation of heme oxygenase 1 (HO-1) expression.

105 ctor erythroid 2-related factor 2 (Nrf2) and heme oxygenase 1 (HO-1) gene proteins in retinal tissues

106 ich then induced the stress-response protein heme oxygenase 1 (HO-1) in dermal fibroblasts.

107 Heme oxygenase 1 (HO-1) is a representative mediator of

108 investigated whether up-regulation of DAF by heme oxygenase 1 (HO-1) is an underlying mechanism by us

109 To assess intracellular heme oxygenase 1 (HO-1) isolated PBMCs were used.

110 e 2 signaling response, downstream of which, heme oxygenase 1 (HO-1) was also found to be time-depend

111 Importantly, mRNA expression of heme oxygenase 1 (HO-1), a potential modulator of immune

112 (hIL-10R) by cmvIL-10 led to upregulation of heme oxygenase 1 (HO-1), an enzyme linked with suppressi

113 ele contained less TNFalpha, MCP-1, and more heme oxygenase 1 (HO-1), and exhibited a higher rate of

114 overexpression of the heme-degrading enzyme, heme oxygenase 1 (HO-1), has been shown to protect mice

115 NAD(P)H:quinone oxidoreductase 1 (NQO1) and heme oxygenase 1 (HO-1), typical chemoprotective gene pr

116 AKI induces upregulation of heme oxygenase 1 (HO-1), which exerts cytoprotective eff

117 on a key enzyme involved in heme catabolism, heme oxygenase 1 (HO-1), which, ironically, has been poo

118 ar adiponectin (gAcrp) are mediated by IL-10/heme oxygenase 1 (HO-1)-dependent pathways.

119 catalase, NF-E2-related factor 2 (Nrf2), and heme oxygenase 1 (HO-1).

120 d expression of the major antioxidant enzyme heme oxygenase 1 (HO-1).

121 t stimulated MMP-1 expression via activating heme oxygenase 1 (HO-1).

122 tional downregulation of the redox regulator heme oxygenase-1 (HO-1 or HMOX1).

123 per-zinc superoxide dismutase (CuZnSOD), and heme oxygenase-1 (HO-1) (antioxidant enzymes) were reduc

124 in 1 (P<0.05), peroxiredoxin 3 (P<0.01), and heme oxygenase-1 (HO-1) (P<0.05), which are up-regulated

125 ffects of carbon monoxide (CO), a product of heme oxygenase-1 (HO-1) activity.

126 Although heme oxygenase-1 (HO-1) acts downstream of vascular endo

127 f2, NAD(P)H quinone oxidoreductase 1 (NQO1), heme oxygenase-1 (HO-1) and a high ratio of Bcl-2/Bax.

128 production of antioxidant enzymes, including heme oxygenase-1 (HO-1) and glutathione peroxidase 1 (Gp

129 of the antioxidant/anti-inflammatory enzyme heme oxygenase-1 (HO-1) and increased neuroinflammation

130 Heme oxygenase-1 (HO-1) and its catabolic by-products ha

131 Heme oxygenase-1 (HO-1) and its metabolic by-product, ca

132 BACKGROUND & AIMS: Heme oxygenase-1 (HO-1) and its metabolic by-product, ca

133 ATF-1 coinduces heme oxygenase-1 (HO-1) and Liver X receptor beta (LXR-b

134 NA and protein levels of HIF-dependent genes heme oxygenase-1 (Ho-1) and manganese superoxide dismuta

135 nd to oxidative stress-induced expression of heme oxygenase-1 (HO-1) and NAD(P)H:quinone oxidoreducta

136 d CXCL8 secretion and required activation of heme oxygenase-1 (HO-1) and phosphorylated adenosine mon

137 cells by the regulations of novel molecules heme oxygenase-1 (HO-1) and programmed death-1 ligand 1

138 An ELISA assay for the Nrf2 target gene heme oxygenase-1 (HO-1) and studies using Nrf2 small int

139 a hypoxia-inducible plasmid expressing both heme oxygenase-1 (HO-1) and the Src homology domain-2 co

140 Despite recent data identifying heme oxygenase-1 (HO-1) as a putative autophagy inducer,

141 AC and selected reaction monitoring revealed heme oxygenase-1 (HO-1) as the most significantly up-reg

142 he cytoprotective and antiapoptotic molecule heme oxygenase-1 (HO-1) at the transcriptional level.

143 Kidney-specific induction of heme oxygenase-1 (HO-1) attenuates the development of an

144 The Nrf2/heme oxygenase-1 (HO-1) axis affords significant protect

145 Heme oxygenase-1 (HO-1) catalyzes the conversion of heme

146 Heme oxygenase-1 (HO-1) catalyzes the degradation of hem

147 Heme oxygenase-1 (HO-1) concentrations have been recentl

148 The enzyme heme oxygenase-1 (HO-1) degrades heme and protects again

149 Heme oxygenase-1 (HO-1) enzyme plays a critical role in

150 a, urine, and tissues, which in turn induces heme oxygenase-1 (HO-1) expression in the colonic epithe

151 We investigated the effect of reduced heme oxygenase-1 (HO-1) expression on vaccine response a

152 vitro study showed that adiponectin induced heme oxygenase-1 (HO-1) expression through the peroxisom

153 We tested the hypothesis that heme oxygenase-1 (HO-1) expression, which is protective

154 ase expression, nitric oxide production, and heme oxygenase-1 (HO-1) expression, which was associated

155 nase-1 (PON-1) expression and down-regulated heme oxygenase-1 (HO-1) expression.

156 al injury, and inhibited RPTC Nrf2, Agt, and heme oxygenase-1 (HO-1) gene expression in Akita Cat tra

157 The donor hearts were also examined for heme oxygenase-1 (HO-1) gene induction.

158 Heme oxygenase-1 (HO-1) gene transcript in the donor hea

159 Catabolism of free heme by heme oxygenase-1 (HO-1) generates carbon monoxide, biliv

160 Heme oxygenase-1 (HO-1) has been demonstrated to protect

161 Heme oxygenase-1 (HO-1) has been viewed as a cytoprotect

162 Heme oxygenase-1 (HO-1) has potent anti-inflammatory act

163 lective overexpression of the stress protein heme oxygenase-1 (HO-1) in astrocytes of novel GFAP.HMOX

164 the products of the cytoprotective molecule heme oxygenase-1 (HO-1) in cancer cells, has been implic

165 of NO induce the anti-inflammatory effector heme oxygenase-1 (HO-1) in gastric epithelial cells thro

166 of the cytoprotective, heme-degrading enzyme heme oxygenase-1 (HO-1) in neutrophil progenitors in bon

167 e antioxidative and anti-inflammatory enzyme heme oxygenase-1 (HO-1) in the brains of individuals wit

168 ed a hypothesized anti-inflammatory role for heme oxygenase-1 (HO-1) in the development of metabolic

169 uanosine (8OHG), 4-hydroxynonenal (HNE), and heme oxygenase-1 (HO-1) in the pyramidal neurons of the

170 Although Heme Oxygenase-1 (HO-1) induction in various forms of ki

171 Heme oxygenase-1 (HO-1) induction in, or carbon monoxide

172 Heme oxygenase-1 (HO-1) induction is a crucial defense m

173 Carbon monoxide or the induction of heme oxygenase-1 (HO-1) inhibited the expression of myof

174 Induction of heme oxygenase-1 (HO-1) inhibits hepatitis C virus (HCV)

175 Heme oxygenase-1 (HO-1) is a cytoprotective protein whos

176 Heme oxygenase-1 (HO-1) is a key enzyme that is indispen

177 Heme oxygenase-1 (HO-1) is a key enzyme triggered by cel

178 Heme oxygenase-1 (HO-1) is a microsomal enzyme with anti

179 Heme oxygenase-1 (HO-1) is a stress-inducible, anti-infl

180 Heme oxygenase-1 (HO-1) is a ubiquitously expressed indu

181 Heme oxygenase-1 (HO-1) is an antioxidant defense and ke

182 Heme oxygenase-1 (HO-1) is an inducible enzyme that exhi

183 Heme oxygenase-1 (HO-1) is an inducible stress-response

184 Heme oxygenase-1 (HO-1) is an inducible stress-responsiv

185 Heme oxygenase-1 (HO-1) is an inducible, detoxifying enz

186 Induction of heme oxygenase-1 (HO-1) is associated with potential ant

187 sed expression of the cytoprotective enzyme, heme oxygenase-1 (HO-1) is often found.

188 The cytoprotective enzyme heme oxygenase-1 (HO-1) is often overexpressed in differ

189 Expression of the cytoprotective enzyme heme oxygenase-1 (HO-1) is significantly reduced in the

190 Heme oxygenase-1 (HO-1) levels were previously shown to

191 ion of host cell antioxidant enzymes such as heme oxygenase-1 (HO-1) may be useful therapeutically to

192 The stress-inducible cytoprotective enzyme heme oxygenase-1 (HO-1) may play a critical role in the

193 The induction of heme oxygenase-1 (HO-1) may protect against tissue injur

194 Induction of heme oxygenase-1 (HO-1) mediates tolerance to the cytoto

195 ukin-8 (IL-8), cyclooxygenase-2 (COX-2), and heme oxygenase-1 (HO-1) mRNA was measured in BEAS-2B cel

196 Treatment with CRA at nontoxic doses induced heme oxygenase-1 (HO-1) mRNA/protein expression and HO-1

197 of inducing the activity of the host enzyme heme oxygenase-1 (HO-1) on hRSV replication and pathogen

198 Induction of heme oxygenase-1 (HO-1) or administration of its product

199 overexpression of the cytoprotective enzyme heme oxygenase-1 (HO-1) play a critical role in the grow

200 Heme oxygenase-1 (HO-1) protein is an antioxidant enzyme

201 epatocellular injury is the up-regulation of heme oxygenase-1 (HO-1) signaling.

202 Only overexpression of the gene encoding heme oxygenase-1 (HO-1) significantly correlated with in

203 Carbon monoxide (CO) generated by heme oxygenase-1 (HO-1) strongly influences cellular pro

204 y amplified in human breast cancers, induced heme oxygenase-1 (HO-1) through Nrf2 transactivation in

205 Hepatocytes overinduced heme oxygenase-1 (HO-1) to catabolize free heme in build

206 gation revealed that the cytoprotective gene heme oxygenase-1 (HO-1) was induced in NF-kappaB-inhibit

207 erythroid 2p45-related factor-2 (Nrf2), and heme oxygenase-1 (HO-1) was tested in both in vitro and

208 up-regulation of the cytoprotective protein heme oxygenase-1 (HO-1) which is capable of mitigating a

209 amplification with pNaKtide and induction of heme oxygenase-1 (HO-1) with cobalt protoporphyrin (CoPP

210 d that PRRSV downregulates the expression of heme oxygenase-1 (HO-1), a pivotal cytoprotective enzyme

211 Heme oxygenase-1 (HO-1), a pivotal cytoprotective enzyme

212 Heme oxygenase-1 (HO-1), an enzyme that catalyzes the ra

213 of oxidative stress caused by low levels of heme oxygenase-1 (HO-1), an important cytoprotective mol

214 transcription of HDAC-repressed genes, e.g. heme oxygenase-1 (HO-1), Gadd45, and HSP70.

215 ter antioxidant transcription factor, and of heme oxygenase-1 (HO-1), one of its main target genes, i

216 ome solid tumors and myeloid leukemia cells, heme oxygenase-1 (HO-1), the anti-oxidant, anti-inflamma

217 Herein, we show that heme oxygenase-1 (HO-1), the inducible isozyme of heme d

218 attention as a master protective sentinel is heme oxygenase-1 (HO-1), the rate-limiting step in the c

219 The wound mRNA levels of heme oxygenase-1 (HO-1), TNF-alpha, the receptor for adv

220 ported in a human patient and mice that lack heme oxygenase-1 (HO-1), we studied iron distribution an

221 Many cancer cells constitutively express heme oxygenase-1 (HO-1), which catabolizes heme to gener

222 is the up-regulation of the inducible enzyme heme oxygenase-1 (HO-1), which catabolizes heme to gener

223 Intracellular heme levels are regulated by heme oxygenase-1 (HO-1), which catalyzes the degradation

224 We therefore investigated the role of heme oxygenase-1 (HO-1), which catalyzes the degradation

225 ng expression of the stress response protein heme oxygenase-1 (HO-1), which interacts with and thereb

226 ory functions, preclinical studies encourage heme oxygenase-1 (HO-1)-inducing regimens in clinical or

227 (WT) animals, and exhibited upregulation of heme oxygenase-1 (HO-1).

228 ctor erythroid 2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1).

229 ion of many cytoprotective enzymes including heme oxygenase-1 (HO-1).

230 e antioxidant response and reduces levels of heme oxygenase-1 (HO-1).

231 4/MyD88-dependent responses via induction of heme oxygenase-1 (HO-1).

232 wn-regulated the expression of antiapoptotic heme oxygenase-1 (HO-1).

233 cisplatin induces the protective antioxidant heme oxygenase-1 (HO-1).

234 d upregulation of the heme-degrading enzyme, heme oxygenase-1 (HO-1).

235 wnregulation of the stress-responsive enzyme heme oxygenase-1 (HO-1).

236 The heme oxygenase-1 (HO-1)/CO pathway modulates cellular re

237 is generated by the stress-responsive enzyme heme oxygenase-1 (HO-1, encoded by Hmox1), which is high

238 Heme oxygenase-1 (HO-1, Hmox1) regulates viability, prol

239 n, protein levels, and enzymatic activity of heme oxygenase-1 (HO-1, the enzyme that produces CO), in

240 The induction of heme oxygenase-1 (HO-1; Hmox1) by inflammation, for inst

241 Heme oxygenase-1 (HO-1; Hmox1) is critical in maintainin

242 quality control is regulated in part by the heme oxygenase-1 (HO-1; Hmox1) system through the redox-

243 Q61L) mutant induced the anti-oxidant enzyme heme-oxygenase-1 (HO-1) through activation of NRF2.

244 stress by upregulating the stress-responsive heme-oxygenase-1 (HO-1).

245 xidant defenses, including the expression of heme-oxygenase-1 (HO-1).

246 kers (matrix metalloproteinase 1 [MMP-1] and heme oxygenase 1 [HO-1]), and proinflammatory cytokines

247 pha, monocyte chemoattractant-1 [MCP-1], and heme oxygenase-1 [HO-1]) was assessed by chromatin immun

248 colocalization of NRF2 and NRP/B and induces heme oxygenase 1 (HO1).

249 In diabetics, up-regulation of heme oxygenase-1 (HO1) in gastric macrophages protects a

250 ), intercellular adhesion molecule 1, IL-10, heme oxygenase 1 hypoxia-inducible factor 1 (HIF-1), mon

251 ssion of hypoxia-inducible factor 1alpha and heme oxygenase 1 in the hippocampus was increased in the

252 The Heme Oxygenase-1 in renal Transplantation study was a ra

253 le to upregulate the atheroprotective enzyme heme oxygenase-1 in response to hemoglobin.

254 synthase derived) regulates the induction of heme oxygenase-1 in the lung, which in turn plays an imp

255 duced expression of the Nrf2 target protein, heme oxygenase-1 in the skin and protected against UVB-i

256 ge-like cell line RAW264.7, (b) induction of heme oxygenase-1 in these RAW cells, and (c) suppression

257 e (HbSS), corresponding with elevated plasma heme oxygenase-1 in this group.

258 several genes, including p53, cyclin G1, and heme oxygenase 1, in embryos.

259 Cobalt protoporphyrin (CoPP), a well known heme oxygenase 1 inducer, has been used to promote endog

260 tor-kappaB, hypoxia-inducible factor-1alpha, heme oxygenase-1, inducible nitric oxide synthase, B-cel

261 Heme oxygenase 1 induction, by counteracting the cytotox

262 vivo and IRAK-M(-/-) AECs in vitro with the heme oxygenase-1 inhibitor, tin protoporphyrin, substant

263 HO-1 (heme oxygenase-1) is an inducible microsomal enzyme that

264 ction, by overcoming its negative regulator, heme oxygenase-1, is a key underlying mechanism responsi

265 a 7-day doxycycline treatment sustained high heme oxygenase-1 levels during the entire period of hypo

266 T6 recruits BAF170 to enhancer region of the Heme oxygenase-1 locus and promotes recruitment of RNA p

267 Heme oxygenase-1 may confer protection from HPH by effec

268 itochondrial superoxide dismutase (SOD), and heme oxygenase-1, mucosal receptors such as the Toll-lik

269 on of antioxidant genes, including those for heme oxygenase 1, NAD(P)H quinone oxidoreductase 1, and

270 e regulation of key Nrf2 target genes (i.e., heme oxygenase-1, NAD(P)H dehydrogenase, quinone 1, glut

271 ificantly upregulates Nrf2-responsive genes, heme oxygenase-1, NAD(P)H quinone oxidoreductase 1, and

272 most robustly increased genes and proteins, heme oxygenase 1, NADPH-quinone oxidoreductase 1, and gr

273 n and expression of the antioxidant proteins heme oxygenase-1, NADPH quinone oxidoreductase 1, and gl

274 such as superoxide dismutase, nitric oxide, heme oxygenase-1, neutrophil infiltration, cysteamine, m

275 -dependent gene and protein markers, such as heme oxygenase-1, occurred, whereas Nrf2-deficient fibro

276 Heme oxygenase 1 (P < 0.01), an oxidative stress marker,

277 gets superoxide dismutase 2 (P <= 0.001) and heme oxygenase 1 (P <= 0.001).

278 es that impair liver regeneration, including heme oxygenase-1, programmed cell death 4, and the cycli

279 ing of PPARgamma to its response elements in heme oxygenase-1 promoter.

280 Experimental data suggest that heme oxygenase-1 protects against kidney disease.

281 t upregulation of superoxide dismutase 2 and heme oxygenase 1 protein following hypoxia-reoxygenation

282 related with CO in the breath were levels of heme oxygenase-1 protein in serum and HMOX1 transcripts

283 , more importantly, amplified renoprotective heme-oxygenase-1 protein and mRNA expression in injured

284 mL; CO-E-CPR, 89 +/- 26 pg/mL; p < 0.05) and heme oxygenase-1 (sham, 1 +/- 0.1; cardiopulmonary resus

285 based proteomics screen, we identified HO-1 (heme oxygenase-1), the rate-limiting enzyme in the degra

286 c-Jun), and heat shock proteins (HSP-70 and heme oxygenase-1) to the HMGCR promoter and transcriptio

287 ced increases of nitric oxide synthase-2 and heme oxygenase-1 transcriptions were also inhibited by 7

288 ted bitransgenic mice that overexpress human heme oxygenase-1 under doxycycline control in an inducib

289 diac function are mediated via Akt-dependent heme oxygenase-1 up-regulation under those conditions.

290 g trauma-hemorrhage occurs via Akt-dependent heme oxygenase-1 up-regulation.

291 Antioxidant capacity and muscularis heme oxygenase-1 upregulation are possible protective me

292 myocardial overexpression of thioredoxin-1, heme oxygenase-1, vascular endothelial growth factor, an

293 Anti-inflammatory and antiapoptotic heme oxygenase-1 was significantly upregulated in the hy

294 Cardiac Akt and heme oxygenase-1 were also determined.

295 ated protein 78), and the antioxidant enzyme heme oxygenase-1 were decreased, whereas levels of infla

296 tide phosphate:quinone oxidoreductase 1, and heme oxygenase-1 were lower in group 2 than group 3.

297 ioxidant enzymes peroxiredoxin-2 (Prdx2) and heme oxygenase-1 were upregulated in cd36-/- VSMCs.

298 pression levels of survival genes, Bcl-2 and heme oxygenase-1, were analyzed by gene array analysis a

299 ulation of H2A histone family, member X, and heme oxygenase 1, which were experimentally validated as

300 rdial nuclear factor E2-related factor 2 and heme-oxygenase 1 with a dietary supplement (Protandim) p