ライフサイエンスコーパス: hemoglobin C

1 with other protective polymorphisms, such as hemoglobin C.

2 Both hemoglobin C and S traits exerted a protective effect ag

3 Individuals expressing hemoglobin C (beta6 Glu-->Lys) present red blood cells (

4 grees -thalassemia (S beta degrees ), sickle-hemoglobin C disease (SC), or sickle-beta(+)-thalassemia

5 obinopathy (sickle-cell disease, sickle-cell hemoglobin C disease, and sickle-cell thalassemia) and a

6 aused by compound heterozygosity for HbS and hemoglobin C genes, is the second most common genotype o

7 l subjects were assayed for hemoglobin S and hemoglobin C genotypes.

8 Hemoglobin C (Glu beta 6-->Lys) shares with hemoglobin S

9 We have studied the self-assembly of Hemoglobin C-Harlem (HbC-Harlem), a double mutant of hem

10 The polymorphisms hemoglobin C (HbC) and hemoglobin S (HbS) - known to pro

11 Although hemoglobin S (HbS) and hemoglobin C (HbC) are well known to protect against sev

12 Although selection of hemoglobin C (HbC) by malaria has been speculated for de

13 Hemoglobin C (HbC) is a possible example in West Africa,

14 Hemoglobin S (HbS) and hemoglobin C (HbC) mutations are frequently encountered

15 und heterozygosity of hemoglobin S (HbS) and hemoglobin C (HbC), comprising 30% of sickle cell diseas

16 HbS that has features in common with that of hemoglobin C (HbC).

17 ism for explaining the protective effects of hemoglobin C (HbC).

18 Sickle cell hemoglobin C (HbSC) disease results from compound hetero

19 ous sickle cell anemia (HbSS), 7 with sickle hemoglobin C (HbSC), 7 with sickle/beta-thalassemia (HbS

20 melting curve analysis for factor V Leiden, hemoglobin C, hemoglobin S, the thermolabile mutation of

21 e findings indicate that schoolchildren with hemoglobin C mutation might contribute disproportionatel

22 hat G6PD deficiency, alpha+ thalassemia, and hemoglobin C protect against malaria mortality; the appl

23 ical characteristics, and laboratory values (hemoglobin, C-reactive protein, and serum albumin).

24 (SS) genotype, 113 (28%) showed sickle cell hemoglobin C (SC) genotype, and 77 (19%) showed trait ge

25 Nine patients had a sickle cell-hemoglobin C (SC) profile, 1 was sickle cell-beta(+) tha

26 b) three sheep received a bolus of 50 mg/kg hemoglobin; c) six sheep received 100 mg/kg of hemoglobi

27 Prevalence of hemoglobin C trait (HbAC) was similarly more common (5%

28 laria in children, but it is unclear whether hemoglobin C trait also protects against uncomplicated m

29 Hemoglobin C trait did not associate with prevalent CKD

30 t that the presence of sickle cell trait and hemoglobin C trait may explain, at least in part, prior

31 nts received 13.2% (P=0.003) higher dose and hemoglobin C trait patients exhibited a similar differen

32 We hypothesized that Malian children with hemoglobin C trait would have a lower risk of clinical m

33 2 patients (10.3% sickle cell trait and 2.4% hemoglobin C trait) receiving ESAs, demographic and clin

34 f-reported blacks (739 with SCT and 243 with hemoglobin C trait).

35 with SCT, six of 243 (2.5%) individuals with hemoglobin C trait, and 234 of 8927 (2.6%) noncarriers.

36 iants, including sickle cell trait (SCT) and hemoglobin C trait, have a role in kidney disease in bla

37 Hemoglobin C trait, like hemoglobin S trait, protects ag

38 ckle cell trait, and 129 (2.4%) patients had hemoglobin C trait; no other hemoglobinopathy traits wer

39 um erythrocyte membrane protein-1 display is hemoglobin C, which may protect against malaria by impai