ライフサイエンスコーパス: hepatic stellate cell

1 d in the liver, their expansion supported by hepatic stellate cells.

2 in embryonic stem cells, gastric tumors, and hepatic stellate cells.

3 ibrogenesis is limited compared with that of hepatic stellate cells.

4 GPR55 in mice, human hepatocytes, and human hepatic stellate cells.

5 l, the L4F nanoparticles were incubated with hepatic stellate cells.

6 pha SMA) revealed a significant reduction in hepatic stellate cells.

7 patocytes, sinusoidal endothelial cells, and hepatic stellate cells.

8 ctivation of neutrophils, Kupffer cells, and hepatic stellate cells.

9 secretion and inhibit collagen deposition in hepatic stellate cells.

10 ta (TGF-beta) signaling pathway in activated hepatic stellate cells.

11 mune response induced by B. abortus-infected hepatic stellate cells.

12 stern diet, indicating reduced activation of hepatic stellate cells.

13 both preneoplastic hepatocytes and activated hepatic stellate cells.

14 duces hepatocyte growth factor production by hepatic stellate cells.

15 les and vitamin A storage, resembled that of hepatic stellate cells.

16 sociated fibroblasts, dermal fibroblasts and hepatic stellate cells.

17 a1) expression suppresses MICA expression in hepatic stellate cells.

18 ocytes activates fibrosis-related markers in hepatic stellate cells.

19 C), as well as primary human hepatocytes and hepatic stellate cells.

20 fibrosis marker activation in primary human hepatic stellate cells.

21 e lineage tracing to follow transplanted rat hepatic stellate cells, a resident liver mesenchymal cel

22 lic fatty liver disease activity scores, and hepatic stellate cell activation (alpha-smooth muscle ac

23 th hepatic alphaSMA expression, a marker for hepatic stellate cell activation (r = -0.31, P < 0.02).

24 hat coincided with alterations in markers of hepatic stellate cell activation and extracellular matri

25 dently benefitted liver fibrosis via altered hepatic stellate cell activation and extracellular matri

26 recedes fibrosis, but is also permissive for hepatic stellate cell activation and fibrosis.

27 Finally, LPI promoted the initiation of hepatic stellate cell activation by stimulating GPR55 an

28 evance, C1QTNF2 expression is reduced during hepatic stellate cell activation in culture and in a mou

29 Finally, MSDC-0602 directly reduced hepatic stellate cell activation in vitro, and MSDC-0602

30 on, L4F nanoparticles were found to suppress hepatic stellate cell activation in vitro.

31 FR reduced hepatic stellate cell activation markers (transforming g

32 LOX inhibition attenuated hepatic stellate cell activation markers and promoted F4

33 idence demonstrate that the hepatic fibrosis/hepatic stellate cell activation may be an important gen

34 suppression of infiltrating macrophages and hepatic stellate cell activation through modulation of i

35 Hepatic stellate cell activation was detected by immunof

36 olic zonation, sinusoid capillarization, and hepatic stellate cell activation were assessed by anti-c

37 mes resulting in hyperammonemia, evidence of hepatic stellate cell activation, and progressive fibros

38 enesis partly mediated through inhibition of hepatic stellate cell activation, and significant decrea

39 ction induced liver fibrosis associated with hepatic stellate cell activation, hepatitis, and liver i

40 ary proliferation, senescence, fibrosis, and hepatic stellate cell activation, which were reduced in

41 phage activation, prothrombin activation and hepatic stellate cell activation.

42 culture models of monocyte/macrophage and/or hepatic stellate cell activation.

43 HCV-activated monocytes/macrophages promoted hepatic stellate cell activation.

44 HO-1 induction significantly suppressed hepatic stellate cell activation.

45 However, the molecular mechanisms for hepatic stellate-cell activation by HCV-infected hepatoc

46 Activated hepatic stellate cell (aHSC)-mediated liver fibrosis is

47 Activated hepatic stellate cells (aHSCs) orchestrate scarring duri

48 tivated myofibroblastic phenotype (activated hepatic stellate cell; aHSCs) expressing smooth muscle a

49 Addition of hepatic stellate cells allowed generation of myeloid-der

50 In vitro experiments were performed in rat hepatic stellate cells and hepatocytes.

51 tumors; and to detect pathways from profiled hepatic stellate cells and hippocampal neurons.

52 We identify potent MMIC activity in hepatic stellate cells and liver sinusoidal endothelial

53 ile a smaller fraction of NPs accumulated in hepatic stellate cells and liver sinusoidal endothelial

54 HCC cells under normoxia and hypoxia, human hepatic stellate cells and LX2 cells, and xenograft tumo

55 ein interactors for galectin-3 in live human hepatic stellate cells and peripheral blood mononuclear

56 triggering cellular senescence in activated hepatic stellate cells and portal fibroblasts by engagin

57 e system to study differentiation of primary hepatic stellate cells and portal fibroblasts from rats

58 ological events, including the activation of hepatic stellate cells and regulation of immune response

59 inct mesothelial cell types as well as early hepatic stellate cells and reveal distinct spatiotempora

60 We found that sGC is expressed in hepatic stellate cells and stellate-derived myofibroblas

61 he MIF receptor, CD74, that is released from hepatic stellate cells and that binds MIF, neutralizing

62 ells), LECs (Liver Endothelial Cells), HSCs (Hepatic Stellate Cells) and/or myofibroblasts to mimic i

63 rate fibrosis in a yin-yang interaction with hepatic stellate cells, and are a key component of tumor

64 , dendritic cells, biliary epithelial cells, hepatic stellate cells, and hepatocytes.

65 promotes fibrogenic activation of attenuated hepatic stellate cells, and limits fibrosis reversal.

66 with eosinophils, neutrophils, macrophages, hepatic stellate cells, and lymphocytes all identified a

67 Endothelin-induced vasoconstriction by hepatic stellate cells, and not platelet accumulation or

68 sion of a subset of TGF-beta target genes in hepatic stellate cells, and the cooperation between the

69 Hepatic stellate cells are key players in the progressio

70 Hepatic stellate cells are liver-specific mesenchymal ce

71 Activated hepatic stellate cells are the main source of excessive

72 were studied using K-562, P815, and primary hepatic stellate cells as targets.

73 ding of the formation and characteristics of hepatic stellate cells, as well as their function in liv

74 nistic target of rapamycin, likely targeting hepatic stellate cells because differentiation and activ

75 poptosis in CAF and in myofibroblastic human hepatic stellate cells but lacked similar effects in qui

76 ver, the major cellular source of HGF is the hepatic stellate cell, but after liver injury, HGF expre

77 s was accompanied by increased activation of hepatic stellate cells, but hepatic mediators of inflamm

78 mide-induced fibrosis, which requires motile hepatic stellate cells, but not from bile duct ligation-

79 rin induces Bmp6 mRNA expression in isolated hepatic stellate cells, but not in hepatocytes.

80 o, AGE exposure decreased Sirt1 and Timp3 in hepatic stellate cells by a NOX2-dependent pathway, and

81 tly induced production of collagen type I in hepatic stellate cells by activating the signal transduc

82 large numbers of hepatocytes, Kupffer cells, hepatic stellate cells, CD4-positive and CD8-positive ly

83 of an in situ liver perfusion system and on hepatic stellate cell contraction in vitro.

84 is, hepatic Rho-kinase activity (a marker of hepatic stellate cell contraction), and the endothelial

85 Instead, hepatic stellate cells cultured on EIIIA-containing cell

86 inhibition of miR-200b in cholangiocytes and hepatic stellate cells decreased the expression of miR-2

87 issue inflammation accompanied with elevated hepatic stellate cell-derived TnC and Toll-like receptor

88 Activation of the autophagic pathway in hepatic stellate cells during Brucella infection could h

89 nd activities of hepatocytes, Kupffer cells, hepatic stellate cells, endothelial cells, and circulati

90 In vitro primary mouse hepatic stellate cells exhibited iRhom2-dependent sheddi

91 MDSC were generated by addition of hepatic stellate cells from various stain mice into dend

92 Mice devoid of Stat3 signaling in hepatic stellate cells (GFAPStat3(-/-) mice) were less s

93 It is becoming increasingly clear that hepatic stellate cells have a profound impact on the dif

94 ors to apoptosis resistance in primary human hepatic stellate cells (hHSC).

95 We have reported that hepatic stellate cells (HpSCs), the stromal cells in the

96 n the transcriptome of rat PMFs, compared to hepatic stellate cell HSC-derived myofibroblasts in cult

97 ceptor (A2AR) activation is known to enhance hepatic stellate cell (HSC) activation and A2AR deficien

98 istration of obeticholic acid (OCA) prevents hepatic stellate cell (HSC) activation and fibrogenesis.

99 ing on the role of inflammatory mediators in hepatic stellate cell (HSC) activation and HSC survival

100 Liver X receptors (LXRs) are determinants of hepatic stellate cell (HSC) activation and liver fibrosi

101 such as dendritic cells (DCs) contribute to hepatic stellate cell (HSC) activation and liver fibrosi

102 ceptor tyrosine kinases, which contribute to hepatic stellate cell (HSC) activation and liver fibrosi

103 Hepatic stellate cell (HSC) activation and transforming

104 Hepatic stellate cell (HSC) activation is a pivotal even

105 Hepatic stellate cell (HSC) activation on liver injury f

106 External stiffness is known to promote hepatic stellate cell (HSC) activation through mechanotr

107 We investigated mechanisms of hepatic stellate cell (HSC) activation, which contribute

108 cantly increased after pIVCL concurrent with hepatic stellate cell (HSC) activation.

109 ive polymerase chain reaction for markers of hepatic stellate cell (HSC) activation.

110 ation of extracellular matrix components and hepatic stellate cell (HSC) activation.

111 I), which enhances TGF-beta signaling during hepatic stellate cell (HSC) activation.

112 is induced as an immediate-early gene during hepatic stellate cell (HSC) activation.

113 nds against oxidative stress, which promotes hepatic stellate cell (HSC) activation.

114 bition could partly account for reduction of hepatic stellate cell (HSC) activation.

115 These pathways included overexpression of hepatic stellate cell (HSC) activators such as fibronect

116 M-CSF-Mphi and IL-34-Mphi also express the hepatic stellate cell (HSC) activators, platelet-derived

117 e role and the molecular mediators of EMT in hepatic stellate cell (HSC) and human liver cancer cells

118 study was to identify the role of Nogo-B in hepatic stellate cell (HSC) apoptosis in cirrhotic liver

119 liferation, LPC biliary differentiation, and hepatic stellate cell (HSC) chemotaxis.

120 rs and consequences of hepatocyte-macrophage-hepatic stellate cell (HSC) crosstalk.

121 tor type 4 (CXCR4) pathway directly promotes hepatic stellate cell (HSC) differentiation and activati

122 thymosin beta-4 (TB4) involved in regulating hepatic stellate cell (HSC) functions remain unclear.

123 MPI in zebrafish liver in vivo and in human hepatic stellate cell (HSC) lines in culture activates f

124 Hepatic stellate cell (HSC) transdifferentiation from a

125 YK expression in the parenchymal hepatocyte, hepatic stellate cell (HSC), and the inflammatory compar

126 sition of extracellular matrix components by hepatic stellate cell (HSC)-derived myofibroblasts.

127 reaction (qRT-PCR) and western blotting and hepatic stellate cell (HSC)-MF contractility by gel cont

128 eceptor type 2 (CCR2) is expressed by active hepatic stellate cells (HSC) and is a key monocyte recru

129 larifying the crosstalk of hepatocytes (HC), hepatic stellate cells (HSC) and liver sinusoidal endoth

130 Erlotinib reduced EGFR phosphorylation in hepatic stellate cells (HSC) and reduced the total numbe

131 ion would normalize crosstalk with activated hepatic stellate cells (HSC) and thereby promote quiesce

132 Hepatic stellate cells (HSC) are a major source of the i

133 Hepatic stellate cells (HSC) are the major cellular cont

134 Hepatic stellate cells (HSC) are the major source of ext

135 Recently, human hepatic stellate cells (HSC) have been reported to induc

136 Activated hepatic stellate cells (HSC) play a critical role in fib

137 n (AR) involvement in liver fibrogenesis and hepatic stellate cells (HSC) regulation is under study.

138 Murine FHL2(-/-) and hepatic stellate cells (HSC) were isolated and investiga

139 s ectopically expressed during activation of hepatic stellate cells (HSC) when it is responsible for

140 -22 ameliorates liver fibrosis by inhibiting hepatic stellate cells (HSC), and loss of miR-200a is as

141 in response (UPR) both promote activation of hepatic stellate cells (HSC), however the link between t

142 e influence on viability and mitochondria of hepatic stellate cells (HSC), the toxicity of the codrug

143 growth factor (CCN2) drives fibrogenesis in hepatic stellate cells (HSC).

144 r are principally regulated by activation of hepatic stellate cells (HSC).

145 system (MLH) comprising primary macrophages, hepatic stellate cells (HSC, LX-2), and hepatocytes (Huh

146 ole of secreted bioactive TGF-beta1 in human hepatic stellate cells (HSCs) activation and invasion.

147 on-kinse (FAK) plays a key role in promoting hepatic stellate cells (HSCs) activation in vitro and li

148 (CTGF) is constantly expressed in activated hepatic stellate cells (HSCs) and acts downstream of TGF

149 was principally expressed in quiescent mouse hepatic stellate cells (HSCs) and directly suppressed pr

150 OPN biological actions were studied in human hepatic stellate cells (HSCs) and in precision-cut liver

151 ed the anti-fibrotic effects of neratinib in hepatic stellate cells (HSCs) and in vivo models of CCl(

152 A to regulate transcription, is expressed by hepatic stellate cells (HSCs) and is required for develo

153 Hepatic stellate cells (HSCs) and portal fibroblasts (PF

154 n induce liver fibrosis remission by killing hepatic stellate cells (HSCs) and producing interferon (

155 Liver repair involves phenotypic changes in hepatic stellate cells (HSCs) and reactivation of morpho

156 IL-20 activated quiescent rat hepatic stellate cells (HSCs) and up-regulated TGF-beta1

157 that accumulate during tissue fibrosis, and hepatic stellate cells (HSCs) are believed to be the maj

158 Hepatic stellate cells (HSCs) are key players in the dev

159 ownstream of TLRs on Kupffer cells (KCs) and hepatic stellate cells (HSCs) are poorly defined.

160 Activated hepatic stellate cells (HSCs) are the major source for a

161 In liver fibrogenesis, hepatic stellate cells (HSCs) are thought to transdiffer

162 ha-actin (SM alpha-actin) is up-regulated in hepatic stellate cells (HSCs) as they transition to myof

163 e factor-1alpha (HIF-1alpha) is activated in hepatic stellate cells (HSCs) by hypoxia and regulates g

164 he hypothesis that the NLRP3 inflammasome in hepatic stellate cells (HSCs) can directly regulate thei

165 Activation of hepatic stellate cells (HSCs) contributes to the develop

166 tyrosine kinase receptor, is up-regulated in hepatic stellate cells (HSCs) during chronic liver injur

167 Effects of LPS on fibrogenic hepatic stellate cells (HSCs) from WT and TLR4-KO mice w

168 Hepatic stellate cells (HSCs) have been identified as th

169 Retinoid-storing hepatic stellate cells (HSCs) have recently been describ

170 ve shown potent immunoregulatory activity of hepatic stellate cells (HSCs) in mice.

171 t the potential role of progenitor cells and hepatic stellate cells (HSCs) in promoting the early eve

172 Activation of hepatic stellate cells (HSCs) in response to injury is a

173 hepatic gammadelta T cells colocalized with hepatic stellate cells (HSCs) in vivo and promoted apopt

174 Hepatic stellate cells (HSCs) induce hepatic inflammatio

175 Hepatic stellate cells (HSCs) inhibit T cells, a process

176 We answered the questions of whether hepatic stellate cells (HSCs) interact with CD4+ T cells

177 the transition of quiescent hepatocytes and hepatic stellate cells (HSCs) into the cell cycle.

178 TGFbeta induces the differentiation of hepatic stellate cells (HSCs) into tumor-promoting myofi

179 Activation of hepatic stellate cells (HSCs) is a critical step in the

180 Activation of hepatic stellate cells (HSCs) is a key event in the init

181 Rho kinase activity in hepatic stellate cells (HSCs) is associated with activat

182 Activation of hepatic stellate cells (HSCs) is crucial to the developm

183 onic liver disease mediated by activation of hepatic stellate cells (HSCs) leads to liver fibrosis.

184 Hepatic stellate cells (HSCs) may play an important role

185 Proliferating cholangiocytes and activated hepatic stellate cells (HSCs) participate in the promoti

186 Hepatic stellate cells (HSCs) play a major role increasi

187 Hepatic stellate cells (HSCs) play critical roles in liv

188 FXR activation in hepatic stellate cells (HSCs) reduces liver fibrosis (LF

189 ammatory and pro-fibrogenic environment with hepatic stellate cells (HSCs) remodeling the extracellul

190 Finally, hepatic stellate cells (HSCs) serve as a hub of intrahep

191 (NKT) cells to the liver to remove activated hepatic stellate cells (HSCs) significantly and ameliora

192 We demonstrated previously that mouse hepatic stellate cells (HSCs) suppress T cells via progr

193 n of matrix proteins, such as collagen I, by hepatic stellate cells (HSCs) that culminates in cirrhos

194 developed a novel model for depleting mouse hepatic stellate cells (HSCs) that has allowed us to cla

195 These secreted cytokines may activate hepatic stellate cells (HSCs) toward fibrosis.

196 Hepatic stellate cells (HSCs) undergo myofibroblastic tr

197 Hh-sensitive, hepatic stellate cells (HSCs) were identified as the sou

198 Kupffer cells and hepatic stellate cells (HSCs) were isolated from WT mice

199 Hepatic stellate cells (HSCs) were recently identified a

200 Hepatic stellate cells (HSCs) were treated with or witho

201 novel Cre-transgenic mouse that marks 99% of hepatic stellate cells (HSCs), a liver-specific pericyte

202 Hepatic stellate cells (HSCs), a population of liver non

203 ading to increased LPA levels, activation of hepatic stellate cells (HSCs), and amplification of prof

204 noreactivity was detected in cholangiocytes, hepatic stellate cells (HSCs), and hepatocytes.

205 o-fibrogenic microenvironment, activation of hepatic stellate cells (HSCs), and progression of biliar

206 ver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs), are the first liver cells

207 ion of myofibroblasts derived from quiescent hepatic stellate cells (HSCs), but the mechanisms that c

208 tion of liver disease is mostly displayed in hepatic stellate cells (HSCs), causing fibrosis/cirrhosi

209 acellular matrix (ECM) cytokine expressed in hepatic stellate cells (HSCs), could drive fibrogenesis

210 In cultured hepatic stellate cells (HSCs), disrupting Hedgehog signa

211 lls of the gastrointestinal tract, including hepatic stellate cells (HSCs), endothelial cells, and he

212 oncomitant with activation and senescence of hepatic stellate cells (HSCs), exhibiting a senescence-a

213 of nonalcoholic steatohepatitis (NASH) using hepatic stellate cells (HSCs), hepatocytes, and mouse mo

214 periments were performed with primary rodent hepatic stellate cells (HSCs), Kupffer cells (KCs), and

215 Activated hepatic stellate cells (HSCs), liver sinusoidal endothel

216 78a-3p, directly targeting Gli3 in activated hepatic stellate cells (HSCs), reduces expression of Gli

217 yte-macrophage colony-stimulating factor and hepatic stellate cells (HSCs), resulting in the generati

218 tamoxifen promotes mechanical quiescence in hepatic stellate cells (HSCs), stromal fibroblast-like c

219 Activated hepatic stellate cells (HSCs), the main fibrogenic cell

220 levels of IL-10R2 and IL-22R1 expression on hepatic stellate cells (HSCs), the predominant cell type

221 A transcriptome signature of activated hepatic stellate cells (HSCs), the primary collagen-secr

222 Hepatic stellate cells (HSCs), the primary mediators of

223 at TGF-beta1 recruited IQGAP1 to TbetaRII in hepatic stellate cells (HSCs), the resident liver pericy

224 uct ligation (BDL) and in cultured activated hepatic stellate cells (HSCs), we show that OPN, besides

225 mechanism of this resistance by focusing on hepatic stellate cells (HSCs), which are known to regula

226 In human cultured hepatic stellate cells (HSCs), which express high levels

227 wth factor beta (TGFbeta) potently activates hepatic stellate cells (HSCs), which promotes production

228 Hepatic fibrosis is marked by activation of hepatic stellate cells (HSCs).

229 ra-epithelial neoplasia, or PDAC, as well as hepatic stellate cells (HSCs).

230 eins including laminin (Ln)-332, produced by hepatic stellate cells (HSCs).

231 o with special focus on the STAT3 pathway in hepatic stellate cells (HSCs).

232 ved exosomes could regulate the phenotype of hepatic stellate cells (HSCs).

233 growth factor-beta (PDGFB) is a mitogen for hepatic stellate cells (HSCs).

234 ions of Kupffer cells (KCs), neutrophils, or hepatic stellate cells (HSCs).

235 d by the deposition of collagen by activated hepatic stellate cells (HSCs).

236 erformed in cell lines of cholangiocytes and hepatic stellate cells (HSCs).

237 e stored as retinyl esters in the retina and hepatic stellate cells (HSCs).

238 SEMA7A is highly expressed in hepatic stellate cells (HSCs).

239 sponse involving TGFbeta1/SMAD activation of hepatic stellate cells (HSCs).

240 is by regulating the fibrogenic phenotype of hepatic stellate cells (HSCs).

241 trafficking in enterocytes, hepatocytes, and hepatic stellate cells (HSCs).

242 othelial cells (LSECs) promote quiescence of hepatic stellate cells (HSCs).

243 ires proliferation and activation of resting hepatic stellate cells (HSCs).

244 iew them as more than just an alternative to hepatic stellate cells in fibrosis.

245 of IL-20 was much higher in hepatocytes and hepatic stellate cells in liver biopsies from patients w

246 ivated B cells (NFkappaB) in hepatocytes and hepatic stellate cells in monoculture; however, they do

247 cant Timp3 gene transcription was induced by hepatic stellate cells in the inflamed liver.

248 inhibition of miR-200b in cholangiocytes and hepatic stellate cells in vitro, we evaluated angiogenes

249 ion of a p53-dependent senescence program in hepatic stellate cells increases liver fibrosis and cirr

250 on of tumor-derived JAG1 signaling activated hepatic stellate cells, increasing their recruitment to

251 We recently demonstrated that hepatic stellate cells induce the differentiation of mye

252 These results demonstrated that hepatic stellate cell-induced MDSCs concurrently suppres

253 Cells showed decreased fibrogenesis, hepatic stellate cell infiltration, Kupffer cells and in

254 r was miniaturized and integrated with human hepatic stellate cells inside microfluidic devices.

255 nitor cells (iPS-HPCs) and human iPS-derived hepatic stellate cell-like cells (iPS-HSCs).

256 ing LHX2, but not in co-culture with a human hepatic stellate cell line (LX-2) overexpressing LHX2.

257 emene (ELE) on the activation of human liver hepatic stellate cell line LX-2 cells.

258 This mechanism was confirmed in a hepatic stellate cell line stably that endogenously expr

259 PA-treated PRHs was applied to cultured rat hepatic stellate cell line, HSC-T6, with or without Flu-

260 l death involving the TRAIL receptors in the hepatic stellate cell line, LX2.

261 1 up-regulation; coculture of hepatocyte and hepatic stellate cell lines significantly increased expr

262 iven profibrogenic program in hepatocyte and hepatic stellate cell lines through ROS, NFkappaB, and T

263 Treatment of hepatic stellate cells (liver cells responsible for fibr

264 e performed in vitro studies on immortalized hepatic stellate cells (LX-2).

265 rix metalloproteinase-1 secretion induced by hepatic stellate cells (LX-2).

266 Human hepatic stellate cells (LX2 cells) were used to assess a

267 ted for up to 21 days using human cell lines hepatic stellate cells (LX2), hepatocellular carcinoma (

268 to activate cultured fibroblasts and primary hepatic stellate cells (myofibroblast precursors in the

269 of studies employing Tg technology to target hepatic stellate cells, myofibroblasts, liver sinusoidal

270 ed production of hepatocyte growth factor in hepatic stellate cells postinjury, which, in turn, resul

271 During liver injury, quiescent hepatic stellate cells (qHSCs) transdifferentiate into p

272 patic fibrosis, attenuated the activation of hepatic stellate cells, reduced frequencies of Th9, Th17

273 ors, liver sinusoidal endothelial cells, and hepatic stellate cells respond to liver injury and contr

274 Primary hepatic stellate cell-seeded hydrogels stiffened in situ

275 muscle actin mRNA), whereas EX increased the hepatic stellate cell senescence marker CCN1 (P < 0.01 v

276 In addition, KCs activate hepatic stellate cells that are involved in liver fibros

277 throughput image-based screen using primary hepatic stellate cells that identified the antifungal dr

278 9 (BMP9) is a circulating factor produced by hepatic stellate cells that plays a critical role in vas

279 as major active component) directly activate hepatic stellate cells, the fibrogenic cell in the liver

280 egression and reduced clearance of activated hepatic stellate cells, the key fibrogenic cell in the l

281 the activation of the autophagic pathway in hepatic stellate cells to create a microenvironment that

282 findings linking senescence and autophagy in hepatic stellate cells to HCC have also been discovered,

283 Praliciguat acted directly on isolated hepatic stellate cells to inhibit fibrotic and inflammat

284 lls, liver sinusoidal endothelial cells, and hepatic stellate cells to liver homeostasis and repair a

285 The TRAIL pathway can mediate apoptosis of hepatic stellate cells to promote the resolution of live

286 bsence of CYLD, gene transcription of HGF in hepatic stellate cells was repressed through binding of

287 sis and DNA damage, whereas proliferation of hepatic stellate cells was stimulated by KCa3.1 inhibiti

288 nthesis; and as ammonia is known to activate hepatic stellate cells, we hypothesized that ammonia may

289 Fibrotic status and the activation of hepatic stellate cells were improved upon pterostilbene

290 nation showed that macrophages and activated hepatic stellate cells were the main cell types expressi

291 CCN1 also induced Jag1 expression in hepatic stellate cells, whereupon they interacted with h

292 The inflammatory cells activate hepatic stellate cells, which are the major source of my

293 parent that the activation of perisinusoidal hepatic stellate cells, which is a key event mediating t

294 sis of liver fibrosis involves activation of hepatic stellate cells, which is associated with depleti

295 -catenin signaling may lead to activation of hepatic stellate cells, which is required for fibrosis.

296 r disease can induce prolonged activation of hepatic stellate cells, which may result in liver fibros

297 omoting ADAM17-mediated shedding of TNFRs in hepatic stellate cells, which reduces TNFR signaling and

298 Treatment of mouse hepatic stellate cells with ethanol significantly increa

299 ons in vitro, we treated rat hepatocytes and hepatic stellate cells with PLS, which caused proteolyti

300 Mechanistically, PTX3 mediated the hepatic stellate cell wound-healing response.