ライフサイエンスコーパス: hermaphrodite

1 ryos (males) but repressed in 2X:2A embryos (hermaphrodites).

2 o accelerate the demise of the opposite sex (hermaphrodites).

3 ed for activation by the male but not by the hermaphrodite.

4 nervous system of the Caenorhabditis elegans hermaphrodite.

5 stressed and unstressed individuals are both hermaphrodite.

6 gland cells (RGC) located in the gut of the hermaphrodite.

7 d mate searching in the male, but not in the hermaphrodite.

8 ells (VPCs), which generate the vulva in the hermaphrodite.

9 briggsae might once have been a facultative hermaphrodite.

10 s, Caenorhabditis elegans, is a self-fertile hermaphrodite.

11 unction of its barnacle host, a simultaneous hermaphrodite.

12 tive success over time, using a simultaneous hermaphrodite.

13 ge in the female system of this simultaneous hermaphrodite.

14 sex-specifically in the non-gonadal soma of hermaphrodites.

15 ation and intense inbreeding by simultaneous hermaphrodites.

16 e transcription from the X between males and hermaphrodites.

17 males and the Y(h) regions of 12 cultivated hermaphrodites.

18 ID produced functional eggs, or self-fertile hermaphrodites.

19 es to have higher seed fitness compared with hermaphrodites.

20 aphrodites), including long-lived or sterile hermaphrodites.

21 tant developmental delay in rict-1 males and hermaphrodites.

22 X Chromosome-wide condensation in C. elegans hermaphrodites.

23 rodites was higher than that of restored CMS hermaphrodites.

24 is programmed in both sexes but repressed in hermaphrodites.

25 ours a capacity for inbreeding by functional hermaphrodites.

26 ood of carrying restorer alleles for non-CMS hermaphrodites.

27 ously identified from Caenorhabditis elegans hermaphrodites.

28 d-type males preferentially mated with older hermaphrodites.

29 ingent on the absence of active sperm in the hermaphrodites.

30 n expression and inhibit sperm production in hermaphrodites.

31 cinal leeches (Hirudo spp.) are simultaneous hermaphrodites.

32 tigated three approaches to producing hybrid hermaphrodites.

33 rodites and in both the germline and soma of hermaphrodites.

34 omones at concentrations that repel solitary hermaphrodites.

35 and behavior in adult Caenorhabditis elegans hermaphrodites.

36 m that restricts pheromone response to adult hermaphrodites.

37 tive memory (LTAM) in Caenorhabditis elegans hermaphrodites.

38 digm predicts that this should also hold for hermaphrodites.

39 pressed to restore homeostasis to C. elegans hermaphrodites.

40 specific mutations is less efficient than in hermaphrodites.

41 rs and physiological processes in C. elegans hermaphrodites [2-5].

42 eromone triggers avoidance behavior in adult hermaphrodites [3-7].

43 l polymorphism, produces males, females, and hermaphrodites [3].

44 s of the species Caenorhabditis remanei into hermaphrodites [6], their sperm were significantly small

45 The co-existence of males, females and hermaphrodites, a rare mating system known as trioecy, h

46 Loss of both snf-10 and a hermaphrodite activation factor render sperm completely

47 Excretory pore plugs are injurious and hermaphrodite activity is compromised in plep-1 mutants,

48 ehavior in response to male pheromone, adult hermaphrodites also require functional germline and egg-

49 Specifically, males crossed with females or hermaphrodites always generate 1:1 male:female or male:h

50 naling and GSC regulation have focused on XX hermaphrodites, an essentially female sex making sperm i

51 Knockdown of multiple DCC components in hermaphrodite and male animals indicates that the dauer

52 he connectomes of the Caenorhabditis elegans hermaphrodite and male nervous systems reveals the exist

53 es widely used by C. elegans researchers (N2 hermaphrodite and male stocks).

54 ips and regulate both sperm release into the hermaphrodite and the recovery from post-coital lethargy

55 tis have a high frequency of self-compatible hermaphrodites and a low frequency of males.

56 lex (DCC) localizes to both X chromosomes in hermaphrodites and downregulates gene expression 2-fold.

57 ystem in plants where populations consist of hermaphrodites and females.

58 f sexually antagonistic alleles that benefit hermaphrodites and harm males [5, 11], or neither of the

59 Laf-1 mRNA is expressed in both males and hermaphrodites and in both the germline and soma of herm

60 In hermaphrodites and larval males, the single cell anal de

61 dioecy to androdioecy (a sexual system where hermaphrodites and males coexist), offering an excellent

62 ave evolved a mating system in which selfing hermaphrodites and males coexist.

63 Thus, crosses between XX hermaphrodites and males yield exclusively male progeny.

64 from androdioecious species (which have both hermaphrodites and males), as predicted by the lower lev

65 ively regulating expression of tra-2 in both hermaphrodites and males.

66 ides a niche for germline stem cells in both hermaphrodites and males.

67 the sexes in overall morphology (two arms in hermaphrodites and one in males) and in the cell types c

68 vel regulator of axonal fusion in C. elegans hermaphrodites and the first regulator of EFF-1 in neuro

69 l X-linked transgenes is balanced between XX hermaphrodites and XO males.

70 n, which balances gene expression between XX hermaphrodites and XO males.

71 ntrations: ascr#3, which is more abundant in hermaphrodites, and ascr#10, which is more abundant in m

72 uscle contraction in the defecation cycle in hermaphrodites, and spicule eversion during mating in th

73 sex-specific small molecule cues secreted by hermaphrodites, and that these preferences emerge from t

74 tivity and quiescence in feeding and fasting hermaphrodites, and we define the neural circuits throug

75 oductive strategy and the effects harmful to hermaphrodites appear to be collateral damage rather tha

76 When hermaphrodites are grown under favorable conditions, the

77 is conclusion, in androdioecious species the hermaphrodites are more vulnerable, the males more benig

78 Here we discover that young C. elegans hermaphrodites are remarkably resistant to brief sexual

79 (C. elegans hermaphrodites are somatic females that transiently prod

80 t is able to attach to, and grow within, the hermaphrodite as well as wild-type bacteria but subseque

81 In nematodes, androdioecy (males/hermaphrodites) as found in Caenorhabditis elegans, is t

82 sixty sensory cilia in the C. elegans adult hermaphrodite at high resolution.

83 of sensory neuron cilia in adult C. elegans hermaphrodites at high resolution.

84 Hermaphrodite attraction to indole ascarosides depends o

85 ces ASK responses in social strains, causing hermaphrodite attraction to pheromones at concentrations

86 roside C9 (ascr#3) is repulsive to wild-type hermaphrodites, attractive to wild-type males, and usual

87 Changes in hermaphrodite attractiveness are tied to the production

88 behaviors include chemotaxis and response to hermaphrodites, backing, turning, vulva location, spicul

89 Thus, newly evolving hermaphrodites became self-fertile by co-opting either o

90 may present a larger mutational target than hermaphrodites because of the different ways in which fi

91 elegans males cause faster somatic aging of hermaphrodites but also manipulate different aspects of

92 f sex-shared phasmid neurons specifically in hermaphrodites but not in males.

93 s not their youthfulness that protects young hermaphrodites, but the fact that they have self-sperm.

94 biological property--contact recognition of hermaphrodites by males during mating--was also found to

95 all cholinergic neuron types in the male and hermaphrodite C. elegans nervous system.

96 ng of the genomes of C. elegans and a second hermaphrodite, C. briggsae, was facilitated in part by t

97 In npr-1 mutant hermaphrodites, C9 repulsion is reduced by the recruitme

98 The hermaphrodite Caenorhabditis elegans germline has become

99 Simultaneous hermaphrodites can function in both male and female role

100 ditis sp. SB347, in which males, females and hermaphrodites co-exist.

101 Similarly, when hermaphrodites co-occur with males, selection should fav

102 ynodioecy, a sexual system where females and hermaphrodites co-occur, is found in << 1% of angiosperm

103 Both restored CMS and non-CMS hermaphrodites co-occur.

104 oecy is a sexual system in which females and hermaphrodites co-occur.

105 plants, such as gynodioecy where females and hermaphrodites coexist.

106 tion coefficient against mutations affecting hermaphrodite competitive fitness agree to within two-fo

107 etitive fitness is 0.17%/generation; that of hermaphrodite competitive fitness is 0.11%/generation.

108 ficantly different from zero, whereas VM for hermaphrodite competitive fitness is similar to that of

109 in which they enhance male responsiveness to hermaphrodite contact.

110 pressor of female development drives male-to-hermaphrodite conversion.

111 While selfing produces XX hermaphrodites, cross-fertilization produces 50% XO male

112 present evidence of a Caenorhabditis elegans hermaphrodite-derived cue that stimulates male mating-re

113 at has a negative but reversible effect on a hermaphrodite-derived mating cue that regulates male mat

114 Mutations in the spe-8 group genes result in hermaphrodite-derived spermatids that cannot activate to

115 Hermaphrodites develop through an obligatory nonfeeding

116 We identified a critical regulator of hermaphrodite development in C. briggsae, named she-1.

117 , an RNA recognition motif protein, triggers hermaphrodite development in XX embryos by causing non-p

118 nto the sex-determination pathway to control hermaphrodite development, but these genes have distinct

119 ation, allowing XX animals to undergo normal hermaphrodite development.

120 In the presence of males, hermaphrodites did not evolve, probably because they wer

121 C. elegans hermaphrodites display dramatic age-related decline of r

122 The hermaphrodite distal tip cell (hDTC) also provides "lead

123 are rare, and the evolutionary interests of hermaphrodites dominate.

124 sensory neurons detect C9 and, in wild-type hermaphrodites, drive C9 repulsion through their chemica

125 the X chromosomes are delayed in mes mutant hermaphrodite embryos.

126 tly activated male developmental programs in hermaphrodite embryos.

127 But whether hermaphrodites evolved counter-strategies against males

128 ctly alternating environments, we found that hermaphrodites evolved the ability to increase embryo gl

129 s, and one subdioecious (males, females, and hermaphrodites), F. virginiana--share the same sex-deter

130 d the mechanisms that regulate female versus hermaphrodite fate in Rhabditis sp. SB347.

131 anema rhodensis [5] varies according to sex (hermaphrodite, female, or male) and type of gametogenesi

132 nt within the three genders; dark female and hermaphrodite flowers had higher sugar content than ligh

133 Most expression changes relative to hermaphrodite flowers occurred in females rather than ma

134 es evolved recently and one which maintained hermaphrodite flowers resembling the ancestral state, to

135 ages of bud development, in male, female and hermaphrodite flowers, identified new loci outside of an

136 ages of bud development, in male, female and hermaphrodite flowers, identified new loci outside of an

137 , to target the DCC to both X chromosomes of hermaphrodites for chromosome-wide reduction of gene exp

138 equencing (RAD-seq) of 47 males, females and hermaphrodites from one dioecious and one androdioecious

139 s nematode species have evolved self-fertile hermaphrodites from the obligately outcrossing females o

140 In C. elegans hermaphrodites, gamete production begins with spermatoge

141 the male disengages or is dislodged from the hermaphrodite genitalia.

142 y that governs the sperm/egg decision in the hermaphrodite germ line of Caenorhabditis elegans has be

143 The distal end of the adult hermaphrodite germline contains the proliferative zone,

144 ffects, for example, the slower aging of the hermaphrodite germline in the presence of physiologicall

145 The hermaphrodite germline of Caenorhabditis elegans initial

146 For example, most mpk-1 ATS are iATS in hermaphrodite germline stem cells, but most are cATS in

147 specific mRNAs from being transcribed in the hermaphrodite germline.

148 morphogenesis, the final U-shapes of the two hermaphrodite gonad arms are determined by migration of

149 he distinct physiological environment of the hermaphrodite gonad.

150 s (GSCs) with properties similar to those of hermaphrodite GSCs (lack of cell cycle quiescence and la

151 As expected, females and hermaphrodites had different nectar reward, with interme

152 SDR haplotypes, we compare male, female, and hermaphrodite haplotype structures and identify sex-link

153 oting attraction or aggregation of wild-type hermaphrodites have been identified.

154 Self-fertile hermaphrodites have evolved independently several times

155 ious and androdioecious populations and that hermaphrodites have likely evolved from females.

156 In hermaphrodites, high odr-10 expression promotes feeding,

157 t for the high frequency of males found with hermaphrodites in a common Mediterranean shrub.

158 Because this species never makes hermaphrodites in the wild, this dimorphism cannot be du

159 cific attraction and aggregation signals for hermaphrodites, in contrast to ascarosides lacking the i

160 ife span of individuals of the opposite sex (hermaphrodites), including long-lived or sterile hermaph

161 Multiple muscle types are impaired in the hermaphrodites, including body wall muscles, pharyngeal

162 Caenorhabditis elegans hermaphrodites initiate spermatogenesis in an otherwise

163 A simultaneous hermaphrodite is capable of functioning in both male and

164 f proliferative germ cells in the C. elegans hermaphrodite is sensitive to the organismal environment

165 Ectopic expression of EGL-5 in hermaphrodites is sufficient to induce male gonadal gene

166 Caenorhabditis elegans produces self-fertile hermaphrodites, it descended from a male/female species,

167 We previously reported a difference in hermaphrodite lifespan between two wild-type lines widel

168 re ciliated nervous system of both males and hermaphrodites, loss of ccpp-1 causes progressive defect

169 These XX hermaphrodites make smaller sperm than males [3, 4], whi

170 ptic strength in many systems, including the hermaphrodite marine mollusk, Aplysia californica Moreov

171 However, hermaphrodites mating in the absence of males evolved gr

172 lore the X chromosome behavior in female and hermaphrodite meioses.

173 l multicolor fluorescence map for the entire hermaphrodite nervous system that resolves all neuronal

174 In hermaphrodites, neuronal expression is initially highly

175 If hermaphrodites occur among females, selection should fav

176 In adult hermaphrodites, odr-10 expression is high, but in well-f

177 The derived hermaphrodite of C. elegans has regulated spermatogenesi

178 ed, first larval stage (L1) of the wild-type hermaphrodite of Caenorhabditis elegans at single-cell r

179 ot shrimp, Pandalus platyceros, a protandric hermaphrodite of commercial importance in North America,

180 o date, only the wiring diagram of the adult hermaphrodite of the nematode Caenorhabditis elegans has

181 We tested these predictions by allowing hermaphrodites of the plant Mercurialis annua to evolve

182 d two pairs of uterine cells in reproductive hermaphrodites only.

183 nsfer, culminating in cross-fertilization of hermaphrodite oocytes with male sperm.

184 ogenesis to yield haplo-X oocytes, during XX hermaphrodite oogenesis they segregate to the first pola

185 on-mediated depletion of NHR-23/NR1F1 within hermaphrodite or male germlines causes sterility due to

186 s between two individuals each chosen from a hermaphrodite or monoecious species.

187 is effect is to the benefit of the male, the hermaphrodite, or both.

188 Y(h) divergence supports the hypothesis that hermaphrodite papaya is a product of human domestication

189 ancestral male population that domesticated hermaphrodite papayas were selected from.

190 pses in a hybrid manner in both the male and hermaphrodite pattern before sexual maturation.

191 hich represses the transcription of dmd-3 in hermaphrodite PHC.

192 omply with 'the inability of a fully fertile hermaphrodite plant to produce zygotes when self-pollina

193 mutation which impairs pollen production in hermaphrodite plants.

194 cy or androdioecy, where males co-occur with hermaphrodites rather than females) have occurred more t

195 uronal functions of tra-1 are not limited to hermaphrodites; rather, tra-1 also acts in the male nerv

196 Second, hermaphrodites recognize pheromone as male if the concen

197 s sperm are very efficient at navigating the hermaphrodite reproductive tract and locating oocytes.

198 ilization site in the Caenorhabditis elegans hermaphrodite reproductive tract.

199 Although C. elegans hermaphrodites require fog-2, which encodes an F box pro

200 Sexual attraction in derepressed hermaphrodites requires the same sensory neurons as in m

201 predicted, it has now been demonstrated that hermaphrodites respond to the removal of males from expe

202 ses the magnitude and the sensitivity of the hermaphrodite response to the male pheromone, restrictin

203 somatic gonadal morphogenesis of lin-28(lf) hermaphrodites results from temporal discoordination bet

204 ty acids in embryos produced by bpl-1 mutant hermaphrodites, revealing a critical role for BPL-1 in l

205 duce and guide a contact-based search of the hermaphrodite's surface for the vulva (the vulva search)

206 les from their tail and insert them into the hermaphrodite's vulva during mating.

207 As the male tail presses against the hermaphrodite's vulva, cholinergic and glutamatergic rec

208 In C. elegans, males and hermaphrodites secrete similar blends of pheromone molec

209 ites always generate 1:1 male:female or male:hermaphrodite sex ratios, respectively, regardless of th

210 es has similar sarcomere morphology, but the hermaphrodite sex-determination system promotes more gro

211 As a hermaphrodite, sex is fluid, and individuals may allocat

212 Sex allocation in hermaphrodites should evolve in response to changes in t

213 tial aspects, suggest that self-incompatible hermaphrodites should have a twofold advantage over dioe

214 ther with Bateman's principles in sequential hermaphrodites, should be formally incorporated in the S

215 eh-18-dependent sperm-sensing pathway of the hermaphrodite somatic gonad.

216 condary (petals and sepals) sexual organs on hermaphrodite species can shed light on general evolutio

217 a sex-linked genes in S. vulgaris (a related hermaphrodite species without sex chromosomes).

218 entify genes important for inhibition of the hermaphrodite-specific motor neurons (HSNs) that stimula

219 ation and serotonin antibody staining of the hermaphrodite-specific neuron (HSN) pair.

220 of the transgene from only two neurons, the hermaphrodite-specific neurons (HSNs), and showed that G

221 Hermaphrodite-specific neurons (HSNs), the executive neu

222 ate the activity of the spontaneously active hermaphrodite-specific neurons (HSNs), which control the

223 riven by a pair of serotonergic neurons, the hermaphrodite-specific neurons (HSNs).

224 lele of the transcription factor HAM-1 [HSN (Hermaphrodite-Specific Neurons) Abnormal Migration].

225 2 or by the selective expression of grk-2 in hermaphrodite-specific neurons.

226 The hermaphrodite-specific region of the Y(h) chromosome (HS

227 y sex chromosome evolution, we sequenced the hermaphrodite-specific region of the Y(h) chromosome (HS

228 The papaya X and the hermaphrodite-specific region of the Y(h) chromosome and

229 However, no examples of a female- or hermaphrodite-specific sex attractant have been identifi

230 We find dmd-4 to promote hermaphrodite-specific synaptic connectivity and neurona

231 Furthermore, the onset of hermaphrodite-specific transcription of sdc-2 (which tri

232 pecificity of dmd-3 action is ensured by the hermaphrodite-specific transcriptional master regulator

233 ess is achieved in Caenorhabditis elegans by hermaphrodite-specific, dosage compensation complex (DCC

234 ntly, little is known about how simultaneous hermaphrodites specify and maintain male and female orga

235 ly labeled sperm revealed that both male and hermaphrodite sperm lacking GSP-3/4 are immotile.

236 During hermaphrodite spermatogenesis, the sister chromatids of

237 ngly, this is to promote, rather than limit, hermaphrodite spermatogenesis.

238 d is necessary and sufficient to specify the hermaphrodite state [3].

239 sexual encounters with males, whereas older hermaphrodites succumb prematurely.

240 which facilitates a systematic search of the hermaphrodite surface for the vulva.

241 Here, we show that hermaphrodites that are briefly exposed to ascr#3 immedi

242 cused on somatic aging, we identified mutant hermaphrodites that displayed extended periods of pharyn

243 with and successfully inseminate C. elegans hermaphrodites that do not concurrently harbor sperm.

244 In this paper, we focus on hermaphrodites that nourish post-zygotic stages, e.g. fl

245 In hermaphrodites the PHC neurons display a canonical patte

246 In the Caenorhabditis elegans hermaphrodite, the developmental sex-determination casca

247 ication of male germ cells in a simultaneous hermaphrodite, the planarian Schmidtea mediterranea.

248 tween Caenorhabditis elegans XO males and XX hermaphrodites through a dosage compensation complex (DC

249 A), which regulates the sex ratio of male to hermaphrodite tissues during the reproductive cycle.

250 e released throughout the body cavity of the hermaphrodite to encounter, and colonize, the developing

251 al depressor development in larval males and hermaphrodites to address how a differentiated cell sex-

252 Self-incompatibility, the ability of hermaphrodites to enforce outcrossing, is frequently los

253 without mating and required only exposure of hermaphrodites to medium in which males were once presen

254 eath cell precursors in L1 to early L2 stage hermaphrodites to permit gonadogenesis.

255 iven by its own promoter allows spe-5 mutant hermaphrodites to produce progeny, indicating that VHA-1

256 that male pheromone acts via this circuit in hermaphrodites to reduce exploration and decrease mating

257 I(DC) binds specifically to X chromosomes in hermaphrodites to regulate transcript levels.

258 The DCC binds to both X chromosomes of hermaphrodites to repress transcription by half.

259 rm maintenance of nuclear HLH-30/TFEB allows hermaphrodites to resist mating-induced death until self

260 n (tm3715) in one such gene (F28D1.8) caused hermaphrodites to show a male germline-dependent self-st

261 we found that males are less attracted than hermaphrodites to the food-associated odorant diacetyl,

262 theca-uterine valve morphology of lin-28(lf) hermaphrodites traps embryos in the spermatheca, which d

263 We grew tetraploid and hexaploid hermaphrodites under different levels of nutrient availa

264 Under adverse conditions, hermaphrodites undergo a prolonged quiescent period as d

265 way to activate sperm, whereas C. tropicalis hermaphrodites use a TRY-5 serine protease pathway.

266 ing, we show that C. elegans and C. briggsae hermaphrodites use the SPE-8 tyrosine kinase pathway to

267 Young Caenorhabditis elegans hermaphrodites use their own sperm to protect against th

268 velocity and inhibiting reversals within the hermaphrodite uterus.

269 ences in reproductive mode (self-fertilizing hermaphrodites versus females) in determining its severi

270 were co-opted for sex determination in each hermaphrodite via their long-standing association with g

271 mproved pkd-2 male response toward spermless hermaphrodites was blocked by prior insemination or by g

272 Siring success of non-CMS hermaphrodites was higher than that of restored CMS herm

273 nhanced response of pkd-2 males toward older hermaphrodites was independent of short-chain ascaroside

274 Increased sex appeal of older hermaphrodites was potent enough to stimulate robust res

275 reens focused on reproductive aging in mated hermaphrodites, we identified mutants that displayed inc

276 the 302 neurons of the nervous system of the hermaphrodite were categorized into 118 neuron classes m

277 Selfing rates of hermaphrodites were low and did not differ significantly

278 wild Xs, probably due to the bottleneck when hermaphrodites were selected during domestication.

279 We show that, in a population of hermaphrodites where male sterility is caused by a domin

280 Reproduction in hermaphrodites, which involves production of both sperm

281 Males prefer mating with females over hermaphrodites, which our results suggest is related to

282 ll abandon food to search for mates, whereas hermaphrodites will not) as well as developmental stage

283 Hermaphrodites with a masculinized nervous system secret

284 -type males, and usually neutral to "social" hermaphrodites with reduced activity of the npr-1 neurop

285 sis (Swip), a paralytic behavior observed in hermaphrodite worms with loss-of-function dat-1 mutation

286 In hermaphrodite worms, CPB-1 and FBF control key steps dur

287 The DCC first localizes to hermaphrodite X chromosomes at the 30-cell stage, coinci

288 richment of histone modification H4K20me1 on hermaphrodite X chromosomes during C. elegans dosage com

289 20 monomethylation (H4K20me1) is enriched on hermaphrodite X chromosomes in a DCC-dependent manner.

290 ctive embryos, we show that the DCC remodels hermaphrodite X chromosomes into a sex-specific spatial

291 tomeres lose their developmental plasticity, hermaphrodite X chromosomes transition from a MES protei

292 ex (DCC), a condensin complex, binds to both hermaphrodite X chromosomes via sequence-specific recrui

293 inds to and represses transcription from the hermaphrodite X chromosomes.

294 reducing Pol II recruitment to promoters of hermaphrodite X-linked genes using a chromosome-restruct

295 n X and autosomes: expression of compensated hermaphrodite X-linked transgenes is half that of autoso

296 pensation condensin complex (DCC) that binds hermaphrodite Xs and establishes megabase-sized topologi

297 C. elegans males (XO) can sometimes exhibit hermaphrodite (XX)-like feeding behavior [1, 2].

298 ent Y chromosomes distinguish males (XY) and hermaphrodites (XY(h)).

299 mutation leading to the domestication of the hermaphrodite Y(h) chromosome.

300 controlling the development of males (Y) and hermaphrodites (Y(h)).