ライフサイエンスコーパス: heterochromatin protein 1

1 ntaining lysine-9 methylated H3 histones and heterochromatin protein 1.

2 rough recruitment of histone deacetylase and heterochromatin protein 1.

3 to chromodomain-containing proteins such as Heterochromatin Protein 1.

4 m regions bound by Polycomb, Histone H1, and heterochromatin Protein 1.

5 ed and unexpected target loci for Drosophila heterochromatin protein 1.

6 ependent H3K9me3 and impairs localization of heterochromatin protein 1.

7 ryonic fibroblasts, Dnmt3a co-localizes with heterochromatin protein 1 alpha (HP1 alpha) and methyl-C

8 eraction domain for the epigenetic remodeler heterochromatin protein 1 alpha (HP1alpha) and isopeptid

9 We show that DEK interacts directly with Heterochromatin Protein 1 alpha (HP1alpha) and markedly

10 NA foci in the nucleus that co-localize with Heterochromatin Protein 1 alpha (HP1alpha), and exhibit

11 was a concomitant increase in the levels of heterochromatin protein 1 alpha (Hp1alpha), suggesting t

12 ), to define the dynamic interactions of the heterochromatin protein-1 alpha (HP1alpha) and the trans

13 rimethylation on lysine 9 of histone H3, and heterochromatin protein 1-alpha in p63-null keratinocyte

14 s recognized by a protein complex containing heterochromatin protein-1 and the DIM-2 DNA methyltransf

15 between proteins that compact the chromatin (heterochromatin protein 1) and the methyltransferases th

16 her defined by H3 trimethylated at lysine 9, heterochromatin protein 1, and histone H4 trimethylated

17 teins HDA-1, CDP-2 (Chromodomain Protein-2), Heterochromatin Protein-1, and CHAP (CDP-2 and HDA-1 Ass

18 chromodomain proteins Polycomb (Pc) and HP1 (heterochromatin protein 1) are highly discriminatory for

19 Across the developmental stages examined, heterochromatin protein 1 associates with variantly expr

20 Heterochromatin protein 1 beta (HP1beta) is abundant in

21 H3S28 and it is necessary and sufficient for heterochromatin protein 1 binding and H3K27me3 recruitme

22 maintaining proper histone modification and heterochromatin protein 1 binding at the pericentric het

23 In this study, we present evidence that heterochromatin protein 1 binding protein 3 (HP1BP3) can

24 We show that EZH2 binds to heterochromatin protein 1 binding protein 3 (HP1BP3) in

25 We observe reduced heterochromatin protein 1 binding protein 3 (HP1BP3) sta

26 ency in neurons activates the translation of heterochromatin protein 1 binding protein 3, which enhan

27 the late S phase, and both are required for heterochromatin protein 1 binding to heterochromatin.

28 sequences for two Xenopus laevis isoforms of heterochromatin protein 1, corresponding to HP1alpha and

29 Fission yeast Swi6 (a Heterochromatin protein 1 counterpart) is a component of

30 inding site on chromatin for proteins of the heterochromatin protein 1 family (HP1).

31 AP1 at Ser-473 attenuated its binding to the heterochromatin protein 1 family proteins and inhibited

32 omoter to recruit DNA methyltransferases and heterochromatin protein 1 for epigenetic modifications.

33 ribonucleic acid polymerase II together with heterochromatin protein 1 gamma (HP1gamma) at NF-kappaB-

34 one H3 lysine 9 trimethylation (H3K9me3) and heterochromatin protein 1 gamma (HP1gamma), as well as r

35 ressor Daxx (a binding partner of HDAC1), or heterochromatin protein 1 gamma resulted in robust and s

36 pression of green fluorescent protein-tagged heterochromatin protein 1 (GFP-HP1) or nontagged HP1 iso

37 These piRNA sources are marked by the heterochromatin protein 1 homolog Rhino (Rhi), which fac

38 In fission yeast, the Heterochromatin Protein 1 homolog Swi6 recognizes H3K9me

39 In contrast, a heterochromatin protein 1 homolog, LHP1, had no effect o

40 n the early embryo and its interactions with heterochromatin protein 1 (HP-1) lead us to speculate th

41 Satellites only accumulated abundant heterochromatin protein 1 (HP1) after replicating in S p

42 ffinity tag system, which was used to purify HETEROCHROMATIN PROTEIN 1 (HP1) and associated proteins

43 We found that heterochromatin protein 1 (HP1) and G9a formed a complex

44 Moreover, ZNF518s interact with heterochromatin protein 1 (HP1) and H3K9 methyltransfera

45 n from Drosophila melanogaster that binds to heterochromatin protein 1 (HP1) and has been implicated

46 Heterochromatin protein 1 (HP1) and HP1-ORC-associated p

47 he genes encoding heterochromatin components heterochromatin protein 1 (HP1) and Su(var)3-9 enhance t

48 e show that borealin interacts directly with heterochromatin protein 1 (HP1) and that this interactio

49 wn heterochromatin-forming proteins, such as heterochromatin protein 1 (HP1) and the histone H2A vari

50 histone H3 lysine 9 methylation (H3K9me) and heterochromatin protein 1 (HP1) are hallmarks of repress

51 histone H3K9 methyltransferase (DIM-5), and heterochromatin protein 1 (HP1) are required for DNA met

52 Loss of ATM reduces the levels of heterochromatin protein 1 (HP1) at telomeres and suppres

53 very of the heterochromatin-enriched protein heterochromatin protein 1 (HP1) by Elgin and co-workers

54 s of DNA damage, we investigated the role of heterochromatin protein 1 (HP1) during the DDR process.

55 The heterochromatin protein 1 (HP1) family is a crucial comp

56 The heterochromatin protein 1 (HP1) family members are canon

57 The heterochromatin protein 1 (HP1) family of proteins is in

58 Members of the diverse heterochromatin protein 1 (HP1) family play crucial role

59 Prohibitin could bind to heterochromatin protein 1 (HP1) family proteins and colo

60 Heterochromatin protein 1 (HP1) family proteins are cons

61 The heterochromatin protein 1 (HP1) family proteins HPL-1 an

62 Although phosphorylation of Heterochromatin Protein 1 (HP1) family proteins regulate

63 essor, which in turn recruits members of the heterochromatin protein 1 (HP1) family.

64 lpha-bound regulatory depots are tethered to heterochromatin protein 1 (HP1) for coordinated chromati

65 w that a young and rapidly evolving X-linked heterochromatin protein 1 (HP1) gene, HP1D2, plays a key

66 Heterochromatin protein 1 (HP1) has been proposed to dri

67 Heterochromatin protein 1 (HP1) has been proposed to pro

68 The heterochromatin protein 1 (HP1) homolog Rhino binds to t

69 ell as Su(var)205; the latter gene codes for heterochromatin protein 1 (HP1) in Drosophila.

70 lysine 9 of histone 3 (H3K9) and binding of heterochromatin protein 1 (HP1) in the promoter regions

71 Tethered heterochromatin protein 1 (HP1) induced H3K9me3, DNA met

72 finger, a PHD domain and a newly identified Heterochromatin Protein 1 (HP1) interaction motif that m

73 Heterochromatin protein 1 (HP1) is a central factor in e

74 Heterochromatin protein 1 (HP1) is a conserved chromosom

75 Heterochromatin protein 1 (HP1) is a conserved component

76 Heterochromatin protein 1 (HP1) is a conserved factor cr

77 Heterochromatin protein 1 (HP1) is a conserved non-histo

78 Heterochromatin protein 1 (HP1) is a key component of co

79 Heterochromatin protein 1 (HP1) is a major component of

80 Heterochromatin protein 1 (HP1) is a nonhistone chromoso

81 Heterochromatin Protein 1 (HP1) is a structural componen

82 Here, we show that heterochromatin protein 1 (HP1) is an essential CPC comp

83 one H3 lysine-9 trimethylation (H3K9me3) and heterochromatin protein 1 (HP1) is essential for proper

84 Heterochromatin protein 1 (HP1) is localized at heteroch

85 Heterochromatin protein 1 (HP1) is well known as a silen

86 rects the binding of nuclear proteins to the heterochromatin protein 1 (HP1) isoforms alpha, beta, an

87 We show that siRNA knockdown of TBX2, EGR1, Heterochromatin Protein 1 (HP1) isoforms and the generic

88 e methyltransferases (KMTs) and compacted by heterochromatin protein 1 (HP1) isoforms, represses alte

89 an increase in repressive H3K9me3 marks and heterochromatin protein 1 (HP1) on the reporter locus.

90 analyzed the genome-wide distribution of the heterochromatin protein 1 (HP1) ortholog HPL-2 and compa

91 be, the H3-K9 methyltransferase Clr4 and the heterochromatin protein 1 (HP1) ortholog Swi6 are critic

92 protein interaction network anchored at the heterochromatin protein 1 (HP1) paralog Rhino.

93 The recruitment of Heterochromatin Protein 1 (HP1) partners is essential fo

94 The identification of heterochromatin protein 1 (HP1) paved the way for a mole

95 Heterochromatin protein 1 (HP1) plays an important role

96 Heterochromatin protein 1 (HP1) proteins are "gatekeeper

97 Heterochromatin protein 1 (HP1) proteins are key factors

98 occur in part as a result of the ability of heterochromatin protein 1 (HP1) proteins to spread acros

99 Heterochromatin protein 1 (HP1) proteins, which are thou

100 ith E2F transcription factors and recruiting heterochromatin protein 1 (HP1) proteins.

101 In Drosophila, heterochromatin protein 1 (HP1) suppresses the expressio

102 A heterochromatin protein 1 (HP1) tethering system was dev

103 tone H3 lysine 9 is important for recruiting heterochromatin protein 1 (HP1) to discrete regions of t

104 nuclear compartments involves the binding of Heterochromatin Protein 1 (HP1) to H3K9me2/3-rich genomi

105 ne 9 (H3 Lys 9), and the specific binding of heterochromatin protein 1 (HP1) to methylated H3 Lys 9.

106 anscription (STAT) physically interacts with heterochromatin protein 1 (HP1) to promote heterochromat

107 Binding of heterochromatin protein 1 (HP1) to the histone H3 lysine

108 heterochromatin, because the chromodomain of heterochromatin protein 1 (HP1) typically recognizes his

109 ervation, Cuff physically interacts with the Heterochromatin Protein 1 (HP1) variant Rhino (Rhi).

110 The Drosophila Heterochromatin Protein 1 (HP1) variant Rhino permits tr

111 The chromoshadow domain (CSD) of heterochromatin protein 1 (HP1) was recently shown to co

112 rtant role in stabilizing the interaction of heterochromatin protein 1 (HP1) with chromatin.

113 ified an interaction between hTAF(II)130 and heterochromatin protein 1 (HP1), a chromatin-associated

114 ral blood monocytes the MIEP associates with heterochromatin protein 1 (HP1), a chromosomal protein i

115 Heterochromatin protein 1 (HP1), a highly conserved non-

116 t that MITR, HDAC4, and HDAC5 associate with heterochromatin protein 1 (HP1), an adaptor protein that

117 Here, we show that heterochromatin protein 1 (HP1), an H3K9me2 and 3 "reade

118 ylation of histone H3 lysine 9 (H3K9me), and heterochromatin protein 1 (HP1), and is a model to inves

119 vo interaction with the epigenetic regulator heterochromatin protein 1 (HP1), and this methyl-depende

120 matin protein like-2 (HPL-2), the homolog of heterochromatin protein 1 (HP1), down-regulates the UPR

121 Heterochromatin protein 1 (HP1), first discovered in Dro

122 its of the origin recognition complex (ORC), heterochromatin protein 1 (HP1), histone H3 trimethyl K9

123 y a chromodomain-containing protein, such as heterochromatin protein 1 (HP1), leading to transcriptio

124 ases (Dnmts) and respective binding proteins heterochromatin protein 1 (HP1), polycomb protein comple

125 ional activation is partially antagonized by heterochromatin protein 1 (HP1), the code reader for his

126 nd acetylation modifications, as well as the Heterochromatin Protein 1 (HP1), to characterise differe

127 n of lysine 9 in histone H3 is recognized by heterochromatin protein 1 (HP1), which directs the bindi

128 Heterochromatin protein 1 (HP1), which interacts with Rb

129 Central to heterochromatin spread is heterochromatin protein 1 (HP1), which recognizes H3K9-m

130 een these two methyl marks is facilitated by heterochromatin protein 1 (HP1), which serves as an adap

131 histone H3 lysine 9 methyltransferase DIM-5, Heterochromatin Protein 1 (HP1), which specifically bind

132 DNA breaks swiftly mobilize heterochromatin protein 1 (HP1)-beta (also called CBX1),

133 rochromatin formation by recruiting multiple heterochromatin protein 1 (HP1)-containing complexes tha

134 histone H3 at lysine 9 (H3K9), which allows heterochromatin protein 1 (HP1)-related chromodomain pro

135 H3 lysine 9 (DiMetH3K9) and the presence of heterochromatin protein 1 (HP1).

136 ion and serve as a specific binding site for heterochromatin protein 1 (HP1).

137 d was enhanced by the classical PEV modifier heterochromatin protein 1 (HP1).

138 acts as a recognition signal for binding of heterochromatin protein 1 (HP1).

139 ks of middle repetitious DNA associated with heterochromatin protein 1 (HP1).

140 act, repressed heterochromatin hallmarked by Heterochromatin Protein 1 (HP1).

141 88, and downstream of the Smc5/6 complex and heterochromatin protein 1 (HP1).

142 omatin including the H3K9me3-binding protein HETEROCHROMATIN PROTEIN 1 (HP1).

143 ine 9 and recruitment of its binding partner heterochromatin protein 1 (HP1).

144 9 of histone H3 (H3K9me), a binding site for heterochromatin protein 1 (HP1).

145 heterochromatin foci involves enrichment of heterochromatin protein 1 (HP1).

146 that controls its reversible association to heterochromatin protein 1 (HP1).

147 uctural and functional homologue of metazoan heterochromatin protein 1 (HP1).

148 terochromatin protein 2 (HP2) interacts with heterochromatin protein 1 (HP1).

149 n homologue (M31) of Drosophila melanogaster heterochromatin protein 1 (HP1; refs 7,8) in transgenic

150 The role of Heterochromatin Protein-1 (HP1) during mitosis has been

151 egulates cohesin-mediated CCAN stability via heterochromatin protein-1 (HP1), Haspin kinase, and phos

152 at, similar to the histone variant macroH2A, heterochromatin protein-1 (HP1), histone H1 and the high

153 our analyses of Rhino, a novel member of the Heterochromatin Protein 1(HP1) subfamily of chromo box p

154 Heterochromatin protein 1 (HP1a in Drosophila) is a cons

155 essor system, two transcriptional repressors-heterochromatin protein 1 (HP1a) and Kruppel-associated

156 Heterochromatin protein 1 (HP1a) has conserved roles in

157 5-encoded methyl-H3-lysine-9 binding protein heterochromatin protein 1 (HP1a)-have been inferred from

158 ins--origin recognition complex 2 (Orc2) and heterochromatin protein 1 (HP1alpha)--in Xi silencing.

159 Heterochromatin protein 1 (HP1beta), a key component of

160 Heterochromatin protein 1 Hsalpha (HP1(Hsalpha)) is one

161 Heterochromatin protein 1(Hsalpha) (HP1(Hsalpha)), one o

162 Here, we show that heterochromatin protein 1 in fission yeast (Swi6) is los

163 Heterochromatin protein 1 is an epigenetic modifier of g

164 B REPRESSIVE COMPLEX 1 (PRC1) component LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) binding throughout the

165 LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) binds Polycomb-deposite

166 Here, we report that A. thaliana LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) is necessary to maintai

167 ard genetic screen for enhancers of the like heterochromatin protein 1 (lhp1) mutant, which shows rel

168 LIKE HETEROCHROMATIN PROTEIN 1 (LHP1), as a component of Poly

169 ng proteins were identified, among them LIKE HETEROCHROMATIN PROTEIN 1 (LHP1).

170 such as proliferating cell nuclear antigen, heterochromatin protein 1, methyl-CpG binding protein 2,

171 f histone H3 at lysine 9, and association of heterochromatin protein 1 on the heterochromatic regions

172 We find heterochromatin protein 1/origin recognition complex-ass

173 n our model, this densification is caused by heterochromatin protein 1's preferential binding to hist

174 Overexpression of heterochromatin protein 1 significantly inhibited E2F1-K

175 sion of JHDM3A abrogates recruitment of HP1 (heterochromatin protein 1) to heterochromatin, indicatin

176 Expression of the heterochromatin protein 1 was increased, and expression

177 nt of the FLC silenced state but not on LIKE HETEROCHROMATIN PROTEIN 1, which functions to maintain s