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1 ide-mediated palladium-catalyzed reductive N-heterocyclization.
2 orresponding 1,5-diketones followed by their heterocyclization.
3 y uncharacterized mode of post-assembly line heterocyclization.
4 is, 1,2-addition of the Normant reagent, and heterocyclization.
5 iocyanates 3 via condensation and subsequent heterocyclization.
6 re crucial for both amide bond formation and heterocyclization.
7  its N-terminal region necessary for peptide heterocyclization.
8  in the precursor to activate asparagine for heterocyclization.
9 atives at a constant current followed by N,S-heterocyclization.
10 -step route based on a biomimetic late-stage heterocyclization.
11              A robust Ag(I)-catalyzed tandem heterocyclization/[3 + 2] cycloaddition of alpha-alkynyl
12 -544) and is the first demonstration of such heterocyclization ability in a nonribosomal peptide synt
13 le for the protein scaffold component of the heterocyclization acceptor substrate.
14                                         Full heterocyclization activity could be restored by providin
15 s not stimulate synthetase reconstitution or heterocyclization activity in vitro.
16  The swapping of PCP2 of HMWP2 abolished the heterocyclization activity of the Cy2 domain while retai
17                                              Heterocyclization activity was reconstituted only by com
18 he second site resulted in a decrease in the heterocyclization activity when MBP-McbB was reconstitut
19 in (MBP), and the in vitro reconstitution of heterocyclization activity.
20 s presented, based on Pd-catalyzed oxidative heterocyclization-alkoxycarbonylation of readily availab
21 lds (56-93%) through a sequential 5-endo-dig heterocyclization-alkoxycarbonylation-dehydration proces
22  and leucine zipper motifs and a specialized heterocyclization and condensation domain found in certa
23  trapping of reactive dicarbonyls by one-pot heterocyclization and into the synthesis of six-membered
24 c and domain-deletion mutagenesis to map the heterocyclization and primary and secondary amine acylat
25                                              Heterocyclization and trans-metalation prior to annulati
26 )phenyl groups efficiently catalyzed diverse heterocyclizations and a cyclopropanation reaction, avoi
27 protection, imination, the key acid-promoted heterocyclization, and aromatization.
28 rtant halogenations, oxidations, aminations, heterocyclizations, and various oxidative functionalizat
29                   Mechanistic aspects of the heterocyclization are discussed.
30 that these cascade Pd(II)-mediated oxidative heterocyclizations are of value for various synthetic ap
31 in dehydration of Ser residues, and backbone heterocyclization at Ser, Thr, and Cys residues to the c
32 ciency of the catalyst- and irradiation-free heterocyclization/bis(triflyl)ethylation sequence showed
33                             Detection of the heterocyclization capacity of HMWP2 1-1491 implies salic
34               Furthermore, the first radical heterocyclization cascade triggered by reduction of amid
35 s rely on Pd(II)-catalyzed aerobic oxidative heterocyclization chemistry, which was employed to rapid
36                          The analysis of the heterocyclization course reveals the dependence of its r
37 RPS modules, the C domain is replaced by the heterocyclization (Cy) domain, a homologous domain that
38              Nonribosomal peptide synthetase heterocyclization (Cy) domains generate biologically imp
39 trophiles and nucleophiles for electrophilic heterocyclization/dealkylation sequences.
40 or 1,3-diketones, followed by dehydration or heterocyclization-dehydration of resulting products, rem
41 ered substrates and intermediates inside the heterocyclization domain and L-cysteinyl adenylate in th
42  protein domains (ArCP, PCP1, PCP2), and two heterocyclization domains (Cy1, Cy2).
43 mechanism for threonyl, seryl, and cysteinyl heterocyclization domains in siderophore and antibiotic
44                             We also examined heterocyclization donor substrate specificity at the lev
45 s and for uncoupling of the condensation and heterocyclization functions of Cy1 and Cy2.
46 ized utilizing two subsequent intramolecular heterocyclizations in one pot.
47                        Novel three-component heterocyclization involving gem-bromofluorocyclopropanes
48              In this route, an electrophilic heterocyclization is followed by ring-opening group tran
49 n contrast to previously reported borylative heterocyclization methods, a reaction here proceeds with
50              Additionally, it leads to a new heterocyclization motif and underlines the utility of ou
51 m of (IMes)Pd(TFA)2(H2O)-catalyzed oxidative heterocyclization of (Z)-4-hexenyltosylamide was investi
52 nzo[d][1,2,3]triazines via an intramolecular heterocyclization of 1-azido-2-[isocyano(p-tosyl)methyl]
53 osphate catalyst promotes the intramolecular heterocyclization of 2-(1-alkynyl)-2-alkene-1-ones and f
54 elopment of a Pd(II)-catalyzed oxidative bis-heterocyclization of alkenes.
55 dihydrothiazoles has been devised by [4 + 1] heterocyclization of alpha-(N-hydroxy/aryl)imino-beta-ox
56 sing InCl(3)- and [Rh]-catalyzed oxidative N-heterocyclization of amino alcohol to form the key amide
57                    This process provides the heterocyclization of electrophilic alkenes.
58 alyze deoxygenative N-N bond-forming Cadogan heterocyclization of o-nitrobenzaldimines, o-nitroazoben
59                                   A one-step heterocyclization of o-nitrobenzylamines to 3-alkoxy-2H-
60            A novel platinum-catalyzed double heterocyclization of propargylic ethers is described.
61 one[ b]-fused BODIPYs, respectively, similar heterocyclization of the 1,3-bis(dimethylaminovinyl)-BOD
62                                        While heterocyclization of the 3-(dimethylaminovinyl)-BODIPY a
63                            Tandem aza-Wittig/heterocyclization of the functionalized aryliminophospho
64  and subsequent base mediated intramolecular heterocyclization of the resulting alpha-hydroxyiminoimi
65 lation by 2,3-dihydrobenzoyl- (DHB-) S-VibB (heterocyclization or Cy domain), heterocyclization to DH
66 amide bond formation) step of the three-step heterocyclization process, while Cy1 is capable of and l
67 enzofused nitrogen heterocycles, and various heterocyclization processes furnish highly substituted a
68 oholic solvent affect the efficiency of this heterocyclization reaction (approximately 40-90%).
69     We used a three-component Biginelli-like heterocyclization reaction for the synthesis of a series
70 ino-2-(trifluoromethyl)-1H-pyrroles from the heterocyclization reaction of 5-bromo-4-methoxy-1,1,1-tr
71               Conversely, the gold-catalyzed heterocyclization reaction of beta-amino-gamma-hydroxyal
72 ished from beta-lactam-linked enynes through heterocyclization reaction taking advantage of the aceto
73 eb amide, followed by an ytterbium-catalyzed heterocyclization reaction with amidines.
74  compounds were found to readily engage in a heterocyclization reaction with elemental sulfur, afford
75 ro, and sulfur compounds was involved in the heterocyclization reaction, and a wide range of function
76        This contrasts sharply with oxidative heterocyclization reactions catalyzed by other nonheme i
77  and regioselectivity in the metal-catalyzed heterocyclization reactions of allenic amino alcohols.
78  harnessed for the development of borylative heterocyclization reactions under ambient-atmosphere con
79                                           As heterocyclization removes the carbonyl following the Ser
80 rocyclic aglycon 7, (i) a six-step classical heterocyclization starting from 5-chloro-1-methyl-4-nitr
81 ear precursor was fundamental to achieve the heterocyclization step as well as obtain the correct reg
82 t not the methyloxazolinyl thioesters of the heterocyclization step.
83 B-) S-VibB (heterocyclization or Cy domain), heterocyclization to DHP-oxazolinyl- and DHP-thiazolinyl
84 ocarbonyl)urethane as the starting material, heterocyclization to the putative "Dts-urethane" does no
85                                          NRP heterocyclizations to thiazoles and oxazoles can occur o
86 h pendant nucleophiles undergo carbonylative heterocyclization triggered by C-C bond activation to ge
87                                      Radical heterocyclizations triggered by electron transfer to ami
88 merase and the conformational changes of the heterocyclization tunnel are controlled by two residues.
89 mation, thus providing examples of reductive heterocyclizations where hydrogen embedded within an alc
90 fluoromethyl)sulfonyl] reaction, followed by heterocyclization, which contrasts with our previous res
91  to further understand the mechanism of this heterocyclization, which occurs in good to excellent yie
92                                   Subsequent heterocyclization with Eaton's reagent yields halo-subst
93 eral types of palladium- and copper-assisted heterocyclizations with the participation of the C ident
94 uirement for ATP or GTP in peptide substrate heterocyclization, with GTP one-third as effective as AT