ライフサイエンスコーパス: heteroduplex

1 of the complementary strand, producing a new heteroduplex.

2 ve site is expanded to accommodate a growing heteroduplex.

3 ide RNA (sgRNA) are present in the sgRNA:DNA heteroduplex.

4 st chromosome to form a physical and genetic heteroduplex.

5 sion to the discontinuous strand of a nicked heteroduplex.

6 nerating increasing or decreasing lengths of heteroduplex.

7 cal geometry into the DNA/RNA portion of the heteroduplex.

8 contacts between REC3 and the guide RNA-DNA heteroduplex.

9 complexes containing a 10- or a 12-base-pair heteroduplex.

10 ge of complementary base pairs to form a new heteroduplex.

11 omplementary cytosine-rich sequences to form heteroduplexes.

12 g activity when interacting with nucleosomal heteroduplexes.

13 tion of loaded beta clamp on either 3' or 5' heteroduplexes.

14 ch with its own rules for mismatch repair of heteroduplexes.

15 RNA duplexes but not DNA duplexes or RNA-DNA heteroduplexes.

16 rna22 identifies most of the currently known heteroduplexes.

17 croRNA binding sites and their corresponding heteroduplexes.

18 ha, which efficiently corrects both types of heteroduplexes.

19 epleted HeLa extract in repair of mismatched heteroduplexes.

20 ctly on the surface concentration of DNA-RNA heteroduplexes.

21 from Ago2 peaks and prediction of miRNA::RNA heteroduplexes.

22 , intramolecular stem-loops into more stable heteroduplexes.

23 tions happen and the specifics of the formed heteroduplexes.

24 usly studied in this respect, cleave RNA/DNA heteroduplexes.

25 he mismatch and a d(GATC) site in a circular heteroduplex abolishes MutH activation, whereas a double

26 sed, the mismatch insensitive binding in the heteroduplex allows short mismatched regions to be incor

27 MutS800 binds a 20-base pair heteroduplex an order of magnitude more weakly than full

28 by single-strand conformational polymorphism-heteroduplex analysis (SSCP-HA) and by direct sequencing

29 The K3326X polymorphism was detected using heteroduplex analysis and DNA sequencing.

30 ded to each unknown before PCR, quantitative heteroduplex analysis can differentiate heterozygous, ho

31 Heteroduplex analysis of clinical samples from geographi

32 mperature-gradient capillary electrophoresis heteroduplex analysis of PCR amplicons of genes and ESTs

33 In the current study, heteroduplex analysis of the ISR was used to determine t

34 givalis strain diversity, we previously used heteroduplex analysis of the ribosomal operon intergenic

35 formed on 7 by PCR of each exon, followed by heteroduplex analysis using denaturing high-performance

36 this study was to apply temperature-mediated heteroduplex analysis using denaturing high-performance

37 onto the RNA array to form a surface RNA-DNA heteroduplex and (ii) the hydrolysis of the RNA microarr

38 yribonucleotide at the catalytic site of the heteroduplex and consisted of southern, northern, and ea

39 Heteroduplex and DNA sequence analyses were then perform

40 exon 10 microsatellite significantly reduced heteroduplex and full mutation in hMLH1(-/-) cells.

41 atin assembly is differentially regulated on heteroduplex and homoduplex substrates.

42 romoting local melting of already formed DNA heteroduplex and transient reverse strand exchange in a

43 e show that a more detailed model, involving heteroduplex and transient-duplex formation, leads to si

44 h RNase H required the presence of a surface heteroduplex and, upon completion, regenerated the origi

45 ridization of different subtypes resulted in heteroduplexes and generated multiple TGCE peaks.

46 es the resolution, with better separation of heteroduplexes and homoduplexes.

47 t with commercial antibodies specific to the heteroduplexes and secondary antibodies conjugated with

48 f these enzymes that can also cleave RNA/DNA heteroduplexes and that may therefore be useful as tools

49 ly in cleaving non-specifically at bulges in heteroduplexes, and single-base mismatches are the least

50 EDC and imidazole, of the hybridized PNA/DNA heteroduplexes, and then they were exploited as the elec

51 fic RNA-DNA antibodies recognizing miRNA-DNA heteroduplexes, antipoly(A)-poly(dT) and anti-S9.6, were

52 Severe distortions of the guide-target heteroduplex are observed in the ruinous 4-sites mismatc

53 or human and mouse miRNAs revealed that many heteroduplexes are "non-canonical" i.e. their seed regio

54 Mismatched base pairs in these heteroduplexes are cleaved by digestion with a single-st

55 In the presence of target miRNA, DNA-RNA heteroduplexes are formed and become substrate for the e

56 After heating and annealing, heteroduplexes are nicked at mismatched sites by the end

57 single-stranded DNA, (2) that the resulting heteroduplexes are resolved by chromosome replication an

58 The CPs together with the QDs in the heteroduplexes are subsequently cleaved off the magnetic

59 on both reparable and irreparable 3' and 5' heteroduplexes as judged by [32P]dAMP incorporation.

60 in the genital tract and blood, we performed heteroduplex assays on amplified env products from cell-

61 he native strand in a native:phosphoramidate heteroduplex at a rate comparable to that observed with

62 We report the development of a heteroduplex-based mutation detection method using multi

63 ctly purifies the single-stranded regions of heteroduplexes between alternative splices formed in the

64 , samples are denatured and annealed to form heteroduplexes between polymorphic DNA strands.

65 pts a bilobed architecture, with the RNA-DNA heteroduplex bound inside the central channel.

66 nd at saturating protein concentrations, the heteroduplex-bound mass observed with MutS800 is only ha

67 , indicating that the subunit copy number of heteroduplex-bound MutS is twice that of MutS800.

68 counter, and is sufficient to unwind RNA-DNA heteroduplex but not duplex DNA.

69 required for genome packaging, disrupts the heteroduplex by binding tightly to U5 (K(d) = 122 +/- 10

70 Incision of a nicked mismatch-containing DNA heteroduplex by this four-protein system is strongly bia

71 es were introduced to the hybridized PNA/DNA heteroduplexes by employing phosphate-zirconium-carboxyl

72 preferential processing of base-base and ID heteroduplexes by MutSalpha and MutSbeta is determined b

73 duplexes and support ribonuclease H mediated heteroduplex cleavage, all with negligible non-specific

74 ltered enzymatic activity toward immobilized heteroduplexes compared to substrates free in solution.

75 drolysis of nucleotide cofactors by the MutS-heteroduplex complex are required for downstream MMR act

76 insic dissociation rate of a particular MutS-heteroduplex complex.

77 Quasispecies emergence was determined via heteroduplex complexity assay.

78 for a C3'-endo conformation, and stabilizes heteroduplexes composed of modified DNA and complementar

79 from D344R, the sequence of which revealed a heteroduplex consistent with Int(Tn916)-mediated excisio

80 ence intensity of cells transfected with the heteroduplex construct divided by that of cells transfec

81 Heteroduplexes contain thermodynamically unstable nucleo

82 Here, we showed that MutS bound to a 30-bp heteroduplex containing an unpaired T with a binding aff

83 ocess DNA loop structures, a set of circular heteroduplexes containing a 30-nucleotide loop were cons

84 Heteroduplexes containing modifications exhibiting stron

85 Finally, modified heteroduplexes containing modifications predicted to mim

86 ased and artifacts are reduced by generating heteroduplexes containing only one of the two possible m

87 pecific recognition and binding of MutS to a heteroduplex, containing either a mismatch or an inserti

88 melting curve separation is proportional to heteroduplex content difference and that the addition of

89 ection system to assay cleavage of amplified heteroduplexes derived from a variety of induced mutatio

90 the mechanism of gene targeting, we examined heteroduplex DNA (hDNA) formation during targeting of tw

91 differences in the extents and locations of heteroduplex DNA (hDNA) in NCO versus CO products.

92 These models differ in the arrangement of heteroduplex DNA (hDNA) in recombination intermediates.

93 y a nondestructive dismantling of mismatched heteroduplex DNA (hDNA) intermediates.

94 e function of Rad54 is removal of Rad51 from heteroduplex DNA (hDNA) to allow HR-associated DNA synth

95 tiating DSB, with a short (<300 bp) tract of heteroduplex DNA (hDNA) to one side and hDNA on the othe

96 Heteroduplex DNA (hetDNA) is a key molecular intermediat

97 entical, there will be mismatches within the heteroduplex DNA (hetDNA).

98 issociating yeast Rad51 protein bound to the heteroduplex DNA after DNA strand invasion.

99 rkers spanning the DSB should be included in heteroduplex DNA and be detectable as non-Mendelian segr

100 e 3' invading strand to be incorporated into heteroduplex DNA and to be extended by DNA polymerases.

101 Mismatches in heteroduplex DNA are recognized and repaired efficiently

102 ous conversion tracts, as well as persistent heteroduplex DNA at crossover sites in mature spermatozo

103 Relaxed heteroduplex DNA containing a two or three-repeat unit e

104 ion between divergent sequences by rejecting heteroduplex DNA containing excessive nucleotide mismatc

105 hought to promote dissociation of RAD51 from heteroduplex DNA following strand exchange during homolo

106 e tract length and directionality, including heteroduplex DNA formation, transcription, replication a

107 with wild-type HIS4 sequence during meiotic heteroduplex DNA formation.

108 cture-specific proteins on TGR frequency and heteroduplex DNA formation.

109 ins are crucial for strand discrimination of heteroduplex DNA formed during ICTS.

110 (OsPERT) was primarily developed to prepare heteroduplex DNA from alkali-denatured high molecular we

111 the repair of 1-nucleotide loop mispairs in heteroduplex DNA generated during meiotic recombination.

112 ed in the rad51Delta mutant, indicating that heteroduplex DNA has an altered structure, or is process

113 ticular type of recombinant containing trans heteroduplex DNA has been observed at two loci.

114 lectrophoretic mobility of homoduplex versus heteroduplex DNA hybrids in high concentration agarose g

115 We have analyzed repair of nicked circular heteroduplex DNA in extracts of Exo1-deficient mouse emb

116 nation in male mice by analyzing patterns of heteroduplex DNA in recombinant molecules preserved by t

117 port of this, analysis of the arrangement of heteroduplex DNA in the postmeiotic segregation products

118 ation in the yeast Saccharomyces cerevisiae, heteroduplex DNA is formed when single-stranded DNAs fro

119 l repeats can be used for repair showed that heteroduplex DNA is likely to be unwound rather than deg

120 Mismatch correction of strand invasion heteroduplex DNA is strongly polar, favouring correction

121 amino acids involved in the stabilization of heteroduplex DNA joints with mismatch-containing base tr

122 ic amino acids gain the ability to stabilize heteroduplex DNA joints with mismatch-containing base tr

123 ad51 protein is stuck on the double-stranded heteroduplex DNA product of DNA strand invasion.

124 g the process of homologous recombination, a heteroduplex DNA structure, or a 'Holliday junction' (HJ

125 actions between polymerase II (Pol II) and a heteroduplex DNA template do not depend on general trans

126 ces to cleave single base pair mismatches in heteroduplex DNA templates used for mutation and single-

127 phosphorylated RPA initially binds to nicked heteroduplex DNA to facilitate assembly of the MMR initi

128 tial fraction of crossover products retained heteroduplex DNA, and some provided evidence of MSH2-ind

129 ive branch migration to extend the region of heteroduplex DNA, even without RecA.

130 Bs) but does not progress beyond this stage; heteroduplex DNA, joint molecules, and crossovers are no

131 Many crossover products yielded no heteroduplex DNA, suggesting dismantling by D-loop migra

132 of 0.7 microm in the absence or presence of heteroduplex DNA.

133 eleting mismatch repair proteins to identify heteroduplex DNA.

134 hat observed with otherwise identical nicked heteroduplex DNA.

135 ous dsDNA undergoes strand exchange yielding heteroduplex dsDNA in site I and the leftover outgoing s

136 d of a double-stranded DNA (dsDNA) and forms heteroduplex dsDNA in site I if homology is encountered.

137 After strand exchange, heteroduplex dsDNA is bound to site I.

138 at the DNA synthesis requires formation of a heteroduplex dsDNA that pairs >20 contiguous bases in th

139 leading end of a RecA/ssDNA filament, while heteroduplex dsDNA unbinds from the lagging end via ATP

140 airing events but, rather, it stimulates DNA heteroduplex extension in the 3' --> 5' direction relati

141 Conversely, Mer3 helicase blocks DNA heteroduplex extension in the 5' --> 3' direction.

142 e stabilizes nascent joint molecules via DNA heteroduplex extension to permit capture of the second p

143 of the Escherichia coli RecA-ssDNA and RecA-heteroduplex filaments.

144 Optimal nicking of heteroduplexes for mismatch detection was achieved using

145 CVR2 exon 3 and 10 microsatellites underwent heteroduplex formation (A(7)/T(8)) in hMLH1(-/-) cells,

146 een homeologous repeats yielded evidence for heteroduplex formation and preferential migration of the

147 ing that mismatches encountered early during heteroduplex formation induce rapid rejection of off-tar

148 dence that DNA strand separation and RNA-DNA heteroduplex formation initiate at the PAM and proceed d

149 racts primarily through base pairing, making heteroduplex formation strictly dependent on complementa

150 equired conformational changes for crRNA-DNA heteroduplex formation.

151 stal gene conversion requires both hMSH2 and heteroduplex formation.

152 mRNA expression in these cells via RNA/mRNA heteroduplex formation.

153 elting studies of Watson-Crick complementary heteroduplexes formed between 2'-O-methyl RNA and RNA ol

154 DNA mismatches are generated when heteroduplexes formed during recombination involve DNA s

155 phoretic analysis of splicing variants where heteroduplexes formed from different variants can produc

156 se H (RNase H) surface hydrolysis of RNA-DNA heteroduplexes formed on DNA microarrays was studied usi

157 oyed enzymatic or physical discrimination of heteroduplexed from homoduplexed target DNA.

158 A multiple-codon-specific heteroduplex generator probe was constructed to improve

159 The protease gene RNA heteroduplex generator-tracking assay (RNA-HTA) was test

160 omplexes were assembled by using a series of heteroduplex HIS4 promoters, TATA binding protein (TBP),

161 fluorescently labeled riboswitch RNA from a heteroduplex in a 5'-to-3' direction, at ~60 nt s(-1) [c

162 nuclease lobes, accommodating the sgRNA:DNA heteroduplex in a positively charged groove at their int

163 Modelling of an RNA-DNA heteroduplex in the interior of this ring demonstrates a

164 The causes of anomalous migration of Ppd-A1 heteroduplexes in gels were found to be the localization

165 acterized the preference of Pif1 for RNA:DNA heteroduplexes in vitro by investigating several kinetic

166 early step for HR pathways is formation of a heteroduplex, in which a single-strand from the broken D

167 ydrolyzable ATP analogue modulates MutSalpha.heteroduplex interaction in a manner that is distinct fr

168 Processing of the irreparable 3' heteroduplex is also associated with incision of the dis

169 hat one-sided events reflect events in which heteroduplex is formed predominantly on only one side of

170 MeG is located on the continuous strand, the heteroduplex is irreparable.

171 Once formed, the DNA-RNA heteroduplex is susceptible to RNAse H enzymatic cleavag

172 n to generate noncrossover products in which heteroduplex is unrepaired.

173 Interestingly, binding of MutSbeta to ID heteroduplexes is greatly stimulated when the MutSalpha:

174 rmodynamic properties of 2'-O-methyl RNA/RNA heteroduplexes is reported.

175 Insertion and deletion of small heteroduplex loops are common mutations in DNA, but why

176 stability experiments conducted on homo- and heteroduplexes made of (S)-ZNA are described that evince

177 te could not be attributed solely to altered heteroduplex melting, strongly suggesting that specific

178 e phosphate groups of the hybridized PNA/DNA heteroduplexes merely through one-step conjugation in th

179 WT/mutant heteroduplexes migrate more slowly and are distinguished

180 Heteroduplex mobility analysis (HMA) is a rapid, inexpen

181 To address this question, heteroduplex mobility analysis (HMA) of portions of the

182 nfected, using clonal frequency analysis via heteroduplex mobility analysis of the second envelope ge

183 assay compared to either the sequence or the heteroduplex mobility assay (HMA)-determined subtypes.

184 -strand conformation polymorphism (SSCP) and heteroduplex mobility assay (HMA).

185 this novel long-amplicon method followed by heteroduplex mobility assay combined with single-strande

186 Polymerase chain reaction combined with a heteroduplex mobility assay was subsequently used to eff

187 orbent assay, reverse transcriptase PCR, the heteroduplex mobility assay, and DNA sequencing.

188 assessed 64 patients for dual infection with heteroduplex mobility assay, viral sequencing, and phylo

189 mobility shift (MMS) values derived from the heteroduplex mobility assay.

190 Heteroduplex mobility assays were unable to distinguish

191 ir sexual partners were analyzed by RFLP and heteroduplex mobility assays.

192 To trigger synthesis, the heteroduplex must be near the 3' end of the initiating s

193 Furthermore, both heteroduplex (n = 21) and phylogenetic (n = 9) analyses

194 moduplexes of DNA, aeg-PNA, gamma-PNA, and a heteroduplex of DNA/aeg-PNA with identical nucleobase se

195 Here we develop a short DNA/RNA heteroduplex oligonucleotide (HDO) with a structure diff

196 striction endonucleases to hydrolyze RNA-DNA heteroduplex oligonucleotide substrates was assessed.

197 bulk, and conformational flexibility of the heteroduplex on enzyme efficiency.

198 g zippering up of 20-bp guide RNA:target DNA heteroduplex on ternary complex formation.

199 vely and repeatedly destroy RNA from RNA-DNA heteroduplexes on gold surfaces; when used in conjunctio

200 o the formation of a high density of PNA/DNA heteroduplexes on the electrode surface for the subseque

201 not be used in analytical methods to resolve heteroduplexes; only with the simplex system can proper

202 some with much lower efficiency than a naked heteroduplex or a heterology free of histone proteins bu

203 most cases, dimorphisms were detected using heteroduplex or single-strand conformational polymorphis

204 e complementary strand, forming either a new heteroduplex or-if homology is limited-a D-loop(1,2).

205 ses this process, through the cooperation of heteroduplex pairing with the binding of ssDNA to the se

206 ns based on single-base mismatch cleavage of heteroduplexed PCR products.

207 The heteroduplex plasmid and a similarly constructed homodup

208 mismatch to G-C or T-A, respectively, in the heteroduplex plasmid generates a functional EGFP gene ex

209 g due to the presence of unprocessed RNA/DNA heteroduplexes, potentially leading to the degradation o

210 s in lower mismatch signals than the RNA-DNA heteroduplexes produced by IVT amplification.

211 and is associated with translocation of the heteroduplex product as well as strand separation of the

212 ors, the MMR system can remove mismatches in heteroduplex recombination intermediates to generate gen

213 cesses are formed and constrained within the heteroduplex region of the D-loop.

214 n in DNA interstrand crosslink repair and/or heteroduplex rejection are mutually exclusive.

215 The involvement of Sgs1p in heteroduplex rejection but not nonhomologous tail remova

216 In contrast, the heteroduplex rejection function of MMR during recombinat

217 In mlh1 Delta strains, heteroduplex rejection was greater than in msh6 Delta st

218 This reduction in heteroduplex rejection was suppressed in a mismatch repa

219 to nonhomologous tail removal during SSA and heteroduplex rejection were characterized.

220 combination between divergent DNA sequences (heteroduplex rejection) during SSA.

221 Deleting PMS1, MLH2,or MLH3 had no effect on heteroduplex rejection, but a pms1 Delta mlh2 Delta mlh3

222 indicate a temporal coupling of MMR, but not heteroduplex rejection, to DNA replication.

223 tion, suppression of synthetic lethality and heteroduplex rejection.

224 t deleting the SGS1 helicase also suppressed heteroduplex rejection.

225 ative MMR and also plays a prominent role in heteroduplex rejection.

226 ided events are the norm but are "hidden" as heteroduplex repair frequently restores the parental con

227 no effect on the distribution of events when heteroduplex repair is lost.

228 In the absence of heteroduplex repair, the first model predicts that two-s

229 arison of the PNA homoduplex and the PNA-RNA heteroduplexes reveals PNA's intrinsic structural proper

230 Knockdown of DHX9 expression by small heteroduplex RNA dramatically blocked the ability of mDC

231 ion: it not only determines the guide-target heteroduplex's nucleation and propagation, but also regu

232 resence of sequence heterogeneity in a given heteroduplex sample by introducing a thermal denaturing

233 Instead, PCR amplification followed by heteroduplex scanning and/or direct nucleotide sequencin

234 A VEGF164/120 heteroduplex species was identified as a PCR artefact, s

235 However, correction of the mismatches within heteroduplex SSA intermediates required PMS1 and MLH1 to

236 and theoretical results suggesting that the heteroduplex stability is insensitive to mismatches.

237 pting a pre-existing stem loop and forming a heteroduplex stabilized by 11 Watson-Crick base pairs (K

238 depends on MutL alpha incision of the nicked heteroduplex strand and dNTP-dependent synthesis-driven

239 ndent instability in the base pairing in the heteroduplex strand exchange product could provide strin

240 ovoked by MeG-T is restricted to the incised heteroduplex strand, leading to removal of the MeG when

241 und that Artemis is capable of nicking small heteroduplex structures and is even able to nick single-

242 RNA-functionalized AuNPs which form DNA-RNA heteroduplex structures through specific hybridization w

243 gar conformation and helical geometry of the heteroduplex substrate at the catalytic site of human RN

244 rminants in the selective recognition of the heteroduplex substrate by human RNase H1 and offer immed

245 y a role in the selective recognition of the heteroduplex substrate by the enzyme.

246 Finally, the heteroduplex substrates exhibited preferred cleavage sit

247 NA elements, and RNA length to slipping on a heteroduplex template using a highly purified human pol

248 active on duplex DNA, were suppressed by the heteroduplex templates, showing that a major function of

249 upport assembly of the yMutLalpha.yMutSalpha.heteroduplex ternary complex.

250 r trans-T(p) by sequestering trans-T(p) in a heteroduplex that is more stable than homoduplex [T(p).T

251 ence of any mutation on the target DNA forms heteroduplexes that are subsequently denatured from the

252 e (MeG), we have constructed nicked circular heteroduplexes that contain a single MeG-T mispair, and

253 By using DNA heteroduplexes that inhibit rewinding of the upstream pa

254 fically recognizes both types of nucleosomal heteroduplexes, the protein bound the mismatch within a

255 sequesters mature miR-122 in a highly stable heteroduplex, thereby inhibiting its function.

256 genes are denatured and re-annealed to form heteroduplexes; they are then incubated with either comp

257 isense oligodeoxyribonucleotide (ASO) of the heteroduplex to alter the helical geometry of the substr

258 exon 10 frameshifts and inability of exon 3 heteroduplexes to fully mutate.

259 ons of the env gene were examined by using a heteroduplex tracking assay (HTA) capable of resolving t

260 Recent work using a heteroduplex tracking assay (HTA) to identify resident v

261 The original heteroduplex tracking assay (HTA) was modified by incorp

262 c variants that could be resolved by using a heteroduplex tracking assay (HTA).

263 We used heteroduplex tracking assay and single-genome sequencing

264 erse transcriptase inhibitor therapy using a heteroduplex tracking assay designed to detect common re

265 HIV-1 env diversity was analyzed by heteroduplex tracking assay in 27 infected subjects with

266 peripheral blood were determined by use of a heteroduplex tracking assay specific for the EBV gene en

267 od plasma and CSF were characterized using a heteroduplex tracking assay targeted to the V1/V2 hyperv

268 ild-type genotype ratio was measured using a heteroduplex tracking assay targeting tenofovir-selected

269 with matching blood were analyzed by using a heteroduplex tracking assay to distinguish LMP1 variants

270 A heteroduplex tracking assay used to genotype Plasmodium

271 ax merozoite surface protein 1 gene (Pvmsp1) heteroduplex tracking assay, we genotyped 107 P. vivax i

272 We have applied heteroduplex tracking assays (HTA) specific to variable

273 om 14 men with chronic HIV-1 infection using heteroduplex tracking assays (HTA).

274 Using heteroduplex tracking assays and direct DNA sequencing,

275 chronic phase of disease, and we analyzed by heteroduplex tracking assays and sequence analysis the d

276 Using heteroduplex tracking assays targeting the highly variab

277 We used heteroduplex tracking assays targeting the variable regi

278 We utilized heteroduplex tracking assays to differentiate CSF HIV-1

279 Using DNA heteroduplex tracking assays, we characterized human imm

280 rehensively examine the variability of major heteroduplex type strains by using the entire genome.

281 of the genomes of seven clinically prevalent heteroduplex type strains identified 133 genes from stra

282 fied 6 predominant geographically widespread heteroduplex types (prevalence, > or = 5%) and 14 rare h

283 ex types (prevalence, > or = 5%) and 14 rare heteroduplex types (prevalence, <2%) which are found in

284 trains in clinical samples and identified 22 heteroduplex types.

285 cess called large loop repair (LLR) corrects heteroduplexes up to several hundred nucleotides in bact

286 has been employed that combines cleavage of heteroduplexes using the Cel nuclease (Cel I), post-clea

287 Cleavage of a fluorescein-labeled RNA-DNA heteroduplex was monitored by capillary electrophoresis.

288 that the difference in MutS K(d) for various heteroduplexes was attributable to the difference in int

289 kinetic association event of MutS binding to heteroduplexes was marked by positive cooperativity.

290 latinated strands (even a unique G3,G4/G4,G5 heteroduplex) were formed.

291 MSH3, together with MSH2, forms the MutSbeta heteroduplex, which interacts with interstrand cross-lin

292 deaminate overhanging DNA strands of RNA/DNA heteroduplexes, which are early intermediates during rev

293 s from a single strand of targeting DNA into heteroduplex with the targeted locus creates a mismatch

294 on, orientation-specific mismatch removal of heteroduplexes with a pre-existing nick was monitored in

295 ing of protease variants isolated as RNA/DNA heteroduplexes with different electrophoretic mobilities

296 Target microRNAs can form DNA: RNA heteroduplexes with DNA probes on the surface of AuNPs,

297 Pol delta, RFC and PCNA, repair occurred on heteroduplexes with loops ranging from 8 to 216 nt.

298 nstead, Pif1 is capable of unwinding RNA:DNA heteroduplexes with moderately greater processivity comp

299 In a sample solution, strands of DV RNA form heteroduplexes with the QD-CPs on the magnetic beads.

300 purely based on thermal denaturation of DNA heteroduplexes without the need for enzymatic reactions.