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1 where females are homogametic and males are heterogametic.
2 nderstanding of how flies with a typical X/Y heterogametic amphogeny (male and female offspring in si
4 These mechanisms include upregulation of the heterogametic chromosome as well as repression in the ho
5 g gene, the dmrt1-paralogue (dm-w) of female-heterogametic clawed frogs (Xenopus; ZW /ZZ ), is known
6 sent a chromosome-level genome assembly of a heterogametic female Atlas blue butterfly (Polyommatus a
9 showing that the ability to produce fertile heterogametic hybrids likely persisted for six million y
12 is largely inactivated in spermatogenesis of heterogametic males, and in multiple phyla it encodes fe
15 zed by Haldane's rule, which states that the heterogametic sex (XY or ZW) suffers the most dysfunctio
16 ve ignored the sex chromosomes unique to the heterogametic sex - Y and W - that are known as sex-limi
18 c sex determination system with males as the heterogametic sex and markedly reduced recombination in
19 ALDANE'S rule postulates that hybrids of the heterogametic sex are more likely to be inviable or ster
22 hibit genetic sex determination, with female heterogametic sex chromosomes (ZZ males, ZW females).
23 lts in the disparity in gene content between heterogametic sex chromosomes and creates the need for d
25 ropose that maintaining the viability of the heterogametic sex drove gene survival on amniote sex-spe
26 of male heterogamety, and the other changing heterogametic sex from XY to ZW, which could be partly e
30 complete genome sequencing confirms that the heterogametic sex is hemizygous for most sex-linked gene
31 with Haldane's rule that postulates that the heterogametic sex is more likely to be absent, rare, or
33 the sexes, as compensatory mutations in the heterogametic sex lead to hyperexpression in the homogam
36 nces of hybrid sterility or inviability, the heterogametic sex tends to be more severely affected.
37 to selection for dosage compensation in the heterogametic sex to rebalance average expression from t
41 must often have involved the emergence of a heterogametic sex-determining locus, the basis of XY and
49 promotes paternal genome elimination in the heterogametic sex; this may incur population extinction
51 ce of the sex-limited chromosome in a female heterogametic species and show that sex-specific selecti
52 ween male and female Z Chromosomes in female heterogametic species, which often lack complete dosage
56 d individuals allowed us to characterize the heterogametic systems of five species (one XY/XX and fou
61 , and their consequences in male- vs. female-heterogametic taxa may explain the pattern of exceptions
64 nterestingly, because butterflies are female heterogametic, this will presumably have also led to the
67 ter size at birth is much more pronounced in heterogametic X*Y females than in homogametic XX or X*X
68 ZW locus on chromosome 5, two separate male heterogametic XY loci on chromosome 7, and two additiona
69 in insects--ranging from the classical male heterogametic XY system in Drosophila to ZW systems in L
70 ely effect fitness within the family, a male heterogametic (XY male) sex determining system evolves,
73 the associated change in gene dosage in the heterogametic (XY) sex is often compensated for by regul
75 copies of this gene indicated that the male heterogametic (XY) system of sex determination in sablef
76 atic sex system consisting of a major female heterogametic ZW locus on chromosome 5, two separate mal
78 a sex chromosome system in which females are heterogametic (ZW) and males are homogametic (ZZ)(1).