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3 At the heart of the replicase machinery is a heteropentameric AAA+ clamp-loading machine that couples
6 ent ligands- we show this to be the case for heteropentameric (alpha4beta2) and homopentameric (alpha
7 f agonist and do not necessitate the complex heteropentameric architecture of the modern-day protein.
8 te that the functional ARC channel pore is a heteropentameric assembly of three Orai1 subunits and tw
9 ture, and their assembly is catalyzed by the heteropentameric Bam complex containing the outer membra
10 system and are driven in part by a class of heteropentameric beta2-containing nicotinic acetylcholin
14 human checkpoint Rad proteins, we purified a heteropentameric complex composed of hRad17-RFCp36-RFCp3
16 at loop extrusion requires the assembly of a heteropentameric complex consisting of the SMC1/SMC3 het
17 d trimeric PIX form an unusual high-affinity heteropentameric complex in which each Spa homology doma
18 Eukaryotic replication factor C (RF-C) is a heteropentameric complex that is required to load the re
26 lar localization and intrinsic properties of heteropentameric GABA(A) receptors themselves also const
28 d alpha5 subunits) in the composition of the heteropentameric GABA(A)-R subunit assembly without a ch
29 urally, GABRP homopentamers closely resemble heteropentameric GABA(A)R anion channels, transitioning
30 lays an important role in forming the mature heteropentameric glycine receptors in these brain stem n
34 nslation initiation factor 2B (eIF2B) is the heteropentameric guanine nucleotide exchange factor for
35 ranslation initiation factor 2B (eIF2B) is a heteropentameric guanine nucleotide exchange factor that
38 tations in the alpha1-subunit (GLRA1) of the heteropentameric human inhibitory glycine receptor (hGly
39 ieu, suggesting that asymmetric occupancy of heteropentameric ion channels by alkylphenol-based anest
41 dult muscle-type acetylcholine receptors are heteropentameric ion channels formed from four different
42 dult muscle-type acetylcholine receptors are heteropentameric ion channels formed from two alpha-subu
45 als that it occurs not only in the classical heteropentameric "monomer" form, but that it also adopts
47 n, and subunit interactions at the two major heteropentameric nicotinic receptors-those governing nic
48 receptors in the central nervous system, are heteropentameric proteins assembled from distinct subuni