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1 unoglobulin-inhibiting reagent, also blocked heterophilic activity.
2     The neuroligin-neurexin complex mediates heterophilic adhesion and can trigger assembly of glutam
3 ting cell adhesion and proliferation, and in heterophilic adhesion as a receptor for E-selectin and N
4 ed to investigate the molecular mechanism of heterophilic adhesion between the murine T-cell adhesion
5 Here, we report the crystal structure of the heterophilic adhesion complex between the amino-terminal
6 Pax3 transfectants having high PSA-NCAM show heterophilic adhesion involving polysialic acid to hepar
7                                 Furthermore, heterophilic adhesion is not substantially weaker than h
8 V and midline glial-expressed Wrapper act as heterophilic adhesion molecules that mediate multiple ce
9 an act in vitro either as a receptor in NCAM heterophilic adhesion or as a promoter of binding betwee
10 ession profiles are complemented by specific heterophilic adhesion patterns of SynCAM family members,
11  that encompass a superfamily of hydrolases, heterophilic adhesion proteins, and chaperone domains re
12         The neuroligin-neurexin complex is a heterophilic adhesion system that promotes assembly and
13  Mel-CAM mediates cell-cell adhesion through heterophilic adhesion to an as yet unidentified ligand p
14 hilic adhesion) or with non-PECAM-1 ligands (heterophilic adhesion).
15 y upregulated expression of genes related to heterophilic adhesion, activation and differentiation ma
16 ellular interactions via both homophilic and heterophilic adhesive mechanisms.
17 4 (also known as SHPS-1, BIT, and SIRP) is a heterophilic adhesive membrane protein involved in recep
18                                          For heterophilic aggregation to occur, a conserved 5-amino a
19 unoglobulin G (IgG) molecule reactive to the heterophilic alpha-Gal epitope [Galalpha-1-3Galbeta1-(3)
20 lobulin G molecule (IgG) that recognizes the heterophilic alpha-gal epitope.
21 he PCDH24 and CDHR5 domains involved in both heterophilic and homophilic adhesion for human and mouse
22 e domains of L1 have been implicated in both heterophilic and homophilic binding, the function of the
23 nematode orthologs ZIG-8 and RIG-5 also form heterophilic and homophilic complexes, and crystal struc
24 ar domains of these proteins are involved in heterophilic and homophilic interactions important for i
25  to L1 through a mechanism that is primarily heterophilic and integrin dependent.
26 lso in other conditions in which RF or other heterophilic antibodies may be present.
27       Serum rheumatoid factor (RF) and other heterophilic antibodies potentially interfere with antib
28                      Signal amplification by heterophilic antibodies was blocked effectively by Heter
29                Assay kinetics indicated that heterophilic antibodies were responsible for the false-p
30 bited significant confounding by RF or other heterophilic antibodies.
31 ch assays to improve reliability by reducing heterophilic antibody interference, thereby improving bi
32 oth SALMs 4 and 5 formed homophilic, but not heterophilic associations, whereas no trans associations
33 esponds with spatiotemporal gradients of two heterophilic atypical cadherins-Fat (Ft) and Dachsous (D
34                    These data establish that heterophilic axonal-L1 interactions mediate adhesion bet
35 orption or were exposed to agents that block heterophilic binding activity.
36 that small differences in the homophilic and heterophilic binding affinities of different type I fami
37 cadherin and, unexpectedly, the N/E-cadherin heterophilic binding affinity is intermediate in strengt
38 ee interactions, others affect homophilic or heterophilic binding alone.
39                     Recent studies show that heterophilic binding between Dsg and desmocollin (Dsc) i
40                   Blocking Abs targeting the heterophilic binding domain of PECAM-1 significantly inh
41 n flies, and reveal roles for homophilic and heterophilic binding in wiring.
42 formed large aggregates, confirming that the heterophilic binding is dominant.
43               Co-expression of complementary heterophilic binding isoform pairs in the same gammaC3-n
44 f the immune system, P84 and IAP represent a heterophilic binding pair that is likely to be involved
45         Recently, NB1 has been shown to be a heterophilic binding partner for the endothelial cell ju
46 etina indicated that cPTPRO has at least one heterophilic binding partner in the retina.
47 84 and integrin associated protein (IAP) are heterophilic binding partners that are expressed in the
48 d immune response through its homophilic and heterophilic binding patterns.
49 ammaC3 chimeric proteins that are capable of heterophilic binding to each other, but incapable of hom
50  known to participate in both homophilic and heterophilic binding, the latter including mechanisms th
51 s suggested that PSA can also be involved in heterophilic binding.
52 n superfamily capable of both homophilic and heterophilic binding.
53                   Two other blocking agents, heterophilic blocking reagent and immunoglobulin-inhibit
54 The mechanical and kinetic properties of the heterophilic bonds are similar to the homophilic interac
55 f chimeric isoforms that bind to each other (heterophilic) but not to themselves (homophilic).
56 ths and dissociation rates of homophilic and heterophilic cadherin (CAD) bonds.
57 differences between different homophilic and heterophilic cadherin dimerizaton affinities can result
58 ne whether the mechanism of aggregation is a heterophilic calcium-dependent process or a homophilic c
59                                          The heterophilic CD2-CD58 adhesion interface contains interd
60 e show that Ft and Ds mediate preferentially heterophilic cell adhesion in vitro, and that each stabi
61  beta-neurexins and neuroligins) function as heterophilic cell adhesion molecules in a Ca2+-dependent
62 1 to evaluate their potential to function as heterophilic cell adhesion molecules.
63 cting with beta-neurexins (beta-NXs) to form heterophilic cell adhesions.
64 hereas the role of CEACAM1 in homophilic and heterophilic cell interactions and immune evasion is wel
65             Thus, mammalian teneurins act as heterophilic cell-adhesion molecules that may be involve
66 s, in addition to binding to latrophilins as heterophilic cell-adhesion molecules.
67 uently lost in carcinomas; it functions as a heterophilic cell-cell adhesion molecule in breast epith
68   Here we show that cell-expansive forces of heterophilic cell-cell adhesion regulate ECD: higher cel
69 cal cadherins suggests a wider prevalence of heterophilic cell-cell adhesion-based ECD regulation dur
70 tic tests validate this mechanism of dynamic heterophilic cell-cell adhesion-based regulation of ECD.
71 fically, isoforms containing exon 14 mediate heterophilic cell-cell aggregation while those variants
72 AMs) that are responsible for homophilic and heterophilic cell-cell interactions.
73  in Drosophila S2 cells, the lectin mediates heterophilic cellular aggregation.
74                                Specifically, heterophilic coiled-coil interactions linked Sstn and St
75 ormation in vivo closely correlates with the heterophilic complex affinity, which appears to be tuned
76 icrovillar tips and interact to form a trans-heterophilic complex.
77 , yet preferentially assemble into specific, heterophilic complexes as shown for the synaptic SynCAM
78            The NTB-A homophilic and CD2-CD58 heterophilic dimers show overall structural similarities
79 ria, numerous gene duplications produced the heterophilic Dprs and DIPs in protostomes, along with tw
80 actions by same-charge repulsion and promote heterophilic Dsg:Dsc interactions through opposite-charg
81                   For each cell, we contrast heterophilic E:N-cadherin binding with the respective ho
82 lack any known PECAM-1 counter receptor, but heterophilic engagement of PECAM-1 can involve glycosami
83           Ft and Ds bind in a preferentially heterophilic fashion, and Ds is expressed in distinct pa
84 in genotypes are also negatively correlated (heterophilic) in friends.
85 ost responded to EHEC infection by promoting heterophilic infiltration of the colonic epithelium and
86 f disseminated anthrax included suppurative (heterophilic) inflammation, edema, fibrin, necrosis, and
87 trate that preferential adhesion mediated by heterophilic interacting cell-adhesion molecules can cre
88 te that the differential localization of two heterophilic interacting nectins mediates the selective
89 matical modeling, we determined that Hh-Ihog heterophilic interaction dominates and Hh can disrupt an
90 on molecules, whereas our findings suggest a heterophilic interaction mechanism.
91                        CD166 displays strong heterophilic interaction with CD6 and weaker homophilic
92  dopamine (mDA) neuron axons through a trans-heterophilic interaction with mDA-bound adhesion molecul
93 le C (JAM-C) was recently shown to undergo a heterophilic interaction with the leukocyte beta2 integr
94 face glycoproteins, which form homophilic or heterophilic interactions across the intercellular space
95 ecules (SynCAMs) 1 and 2 engage in homo- and heterophilic interactions and bridge the synaptic cleft
96 owth and neuronal survival in homophilic and heterophilic interactions and enhances neurite outgrowth
97 eneficial functions of L1 via homophilic and heterophilic interactions are functionally optimized and
98  and specific homophilic, and in some cases, heterophilic interactions between cells.
99 are remarkably precise, with no evidence for heterophilic interactions between different isoforms.
100                                   Initially, heterophilic interactions between glial and axonal cell
101  experiments for interactions of TRAILR2 and heterophilic interactions between the two death receptor
102 eristic repeats that regulate homophilic and heterophilic interactions during adhesion and cell sorti
103 rthermore, Ncad isoforms mediate promiscuous heterophilic interactions in an in vitro cell-aggregatio
104      Our results suggest that homophilic and heterophilic interactions involving PCDH24 and CDHR5 are
105 a to human CEACAM1, and other homophilic and heterophilic interactions of CEA family members.
106 epithelial cells, probably via homophilic or heterophilic interactions of the PKD domains.
107 s as a result of the numerous homophilic and heterophilic interactions that CEACAM1 can have with its
108 rvous system are triggered by homophilic and heterophilic interactions that stimulate signal transduc
109                    Many chemokines engage in heterophilic interactions to form heterodimers, leading
110 egate cells, Fat and Dachsous cadherins form heterophilic interactions to induce cell polarity within
111       Neurexin and neuroligin, which undergo heterophilic interactions with each other at the synapse
112 1 N-terminal domain are not only involved in heterophilic interactions with Opa proteins and H influe
113 AMs are brought about through homophilic and heterophilic interactions with other cell surface recept
114 where it bridges cells through homophilic or heterophilic interactions with other nectins.
115 ng affinities associated with homophilic and heterophilic interactions within the nectin family.
116 omains of L1 are required for homophilic and heterophilic interactions.
117 hat its effects on outgrowth are mediated by heterophilic interactions.
118  specific and are mediated by homophilic and heterophilic interactions.
119 de a structural basis for teneurin homo- and heterophilic interactions.
120 te cell-cell adhesion through homophilic and heterophilic interactions.
121 omophilic adhesion, homophilic repulsion and heterophilic interactions.
122 specificity in homophilic binding as well as heterophilic interactions.
123 ertoli and germ cells through homophilic and heterophilic interactions.
124                                Homophilic or heterophilic L1 binding and concomitant signaling have b
125 the activation of the myosin phosphatase via heterophilic leucine zipper interactions between its tar
126 sults suggest a model in which Nrg acts as a heterophilic ligand and activator of Ed, which in turn a
127 omain of human L1 (L1-Ig6) can function as a heterophilic ligand for multiple members of the integrin
128                    Thus, CEACAM1 serves as a heterophilic ligand for TIM-3 that is required for its a
129 r activation, but can also be activated by a heterophilic ligand, Gas6, a member of the family of vit
130 noglycans have been implicated as one of the heterophilic ligands for PECAM-1.
131 exploitation of homophilic and possibly also heterophilic mechanisms of neural stem cells overexpress
132    First, it can mediate cell adhesion via a heterophilic molecular interaction.
133 ative cell line, consistent with an ALCAM-L1 heterophilic molecular interaction.
134 homophilic PECAM-PECAM-1 engagement, but not heterophilic neutrophil PECAM-1 interactions, and is int
135 hus determine whether PECAM-1 functions as a heterophilic or homophilic adhesion molecule by processe
136 hat the Necl proteins preferentially mediate heterophilic rather than homophilic interactions.
137                              2B4 is the only heterophilic receptor of the SLAM family, whose other me
138 eural IgCAMs function as both homophilic and heterophilic receptors for a variety of cell-surface and
139 lecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and i
140 lecule (SLAM) family includes homophilic and heterophilic receptors that regulate both innate and ada
141  receptors thought to provide homophilic and heterophilic recognition specificity for neuronal wiring
142         This analysis revealed the basis for heterophilic recognition within the SLAM family.
143 hn2, revealing that Lphn2- and Ten3-mediated heterophilic repulsion and Ten3-mediated homophilic attr
144 as homophilic cell adhesion molecules and as heterophilic repulsive ligands of Unc5/Netrin receptors.
145 r these effects, suggesting the existence of heterophilic signaling.
146 tion experiments, we demonstrate family-wise heterophilic specificity: All Dsgs form adhesive dimers
147  homophilic and an immune system gene set is heterophilic, suggesting that these systems may play a r
148 n unusual orthogonal docking geometry in the heterophilic SYG-1/SYG-2 complex.
149 support stable cell adhesion, different from heterophilic teneurin-latrophilin binding.
150 ine phosphorylation and led to a switch from heterophilic to homophilic aggregation.
151 sults in a change in ligand specificity from heterophilic to homophilic binding.
152 ace change the mechanism of aggregation from heterophilic to homophilic, and 4) PECAM-1-dependent hom
153 ilic adhesion molecule and also engages in a heterophilic trans-interaction with Drosophila Neuroglia
154 gs strongly suggest that steric hindrance of heterophilic transinteraction between Dsg and Dsc is imp
155 efine SynCAM proteins as components of novel heterophilic transsynaptic adhesion complexes that set u
156 vide a mechanistic basis to explain stronger heterophilic versus weaker homophilic interactions among

 
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