ライフサイエンスコーパス: heterozygosity

1 , or for TYK2 I684S or V362F homozygosity or heterozygosity.

2 ion, enriched at QTL and regions of residual heterozygosity.

3 expressing mice were rescued by Rpl24(Bst/+) heterozygosity.

4 r fitness in individuals with higher genomic heterozygosity.

5 on or high percentage of genome-wide loss of heterozygosity.

6 genic annotation scores, total LD scores and heterozygosity.

7 l for chromosomal rearrangements and loss of heterozygosity.

8 vidual with sporadic SRNS exhibited compound heterozygosity.

9 h allelic diversity, mainly due to very high heterozygosity.

10 d fitness as a result of reduced genome-wide heterozygosity.

11 expose deleterious mutations through loss of heterozygosity.

12 orrelating STR genotypes with local sequence heterozygosity.

13 h 1p and 16q copy number loss and/or loss of heterozygosity.

14 ce, self-incompatibility, and high levels of heterozygosity.

15 versity, pedigree analysis, and detection of heterozygosity.

16 tigmatic pollen loads, outcrossing rates and heterozygosity.

17 om the normal meiotic program that maintains heterozygosity.

18 ood of a translocated individual's survival: heterozygosity.

19 and cell-free DNA samples revealing loss of heterozygosity.

20 duals, we also explored the role of compound heterozygosity.

21 with population-level differences in genetic heterozygosity.

22 sfunction), and 4 with MYH6-FLNC synergistic heterozygosity.

23 ellite-derived host population structure and heterozygosity.

24 ained by female hemizygosity rather than low heterozygosity.

25 separate into seven groups with 0.73 to 0.79 heterozygosity.

26 strated a high level of copy-neutral loss of heterozygosity.

27 ating locus through whole-chromosome loss of heterozygosity.

28 be obtained that retain genome-wide parental heterozygosity.

29 vel copy number alterations, and HLA loss of heterozygosity.

30 tively high P. vivax genetic diversity (mean heterozygosity, 0.843 [range 0.570-0.989] with low multi

31 associated relapse (20% relapse with loss of heterozygosity, 25% with loss of imprinting, and 3.3% re

32 al congenital heart disease, 4 with compound heterozygosity (3 with systolic ventricular dysfunction)

33 mprovement have been limited because of high heterozygosity, a very large genome size with a high lev

34 uding cases with clonal copy-neutral loss-of-heterozygosity affecting class I HLA genes (8.6% of case

35 This genetic approach involves detecting heterozygosity along chromosomes in segregating populati

36 sease, we computed the regression of average heterozygosity and average allele frequency of the risk

37 Loss of heterozygosity and decreased copy number delimited inter

38 We estimate levels of heterozygosity and find particularly low levels in an in

39 we identified a positive association between heterozygosity and fitness, indicating that inbreeding i

40 mutant mice and mice with pan-cellular Tcf4 heterozygosity and found that they exhibited hippocampal

41 an, and that the relationship between higher heterozygosity and healthy aging could be explained by h

42 Identified genetic groups vary in heterozygosity and levels of linkage, suggesting differe

43 interaction in mouse embryos between Notch1 heterozygosity and low oxygen- or anti-arrhythmic drug-i

44 excessive genetic risk imposed by HLA-DQ2/8 heterozygosity and may assist immune monitoring of disea

45 ers and cell lines, we find frequent loss of heterozygosity and mutations in BCL9L in aneuploid tumor

46 uction of MF phylogeny demonstrating loss of heterozygosity and parallel evolution as recurrent event

47 We propose that D. pachys preserves heterozygosity and produces diploid embryos without fert

48 To investigate interactions between heterozygosity and recombination we crossed Arabidopsis

49 g pollinator reliability, outcrossing rates, heterozygosity and relevant floral traits across populat

50 Due to DNA heterozygosity and repeat content, assembly of non-model

51 er relatedness-lower magnitude reductions in heterozygosity and significant reductions in allelic ric

52 Finally, we demonstrate that loss of heterozygosity and temporal dissection of mutations can

53 how TGCTs gain additional reciprocal loss of heterozygosity and that this is associated with loss of

54 egression model trained on both X chromosome heterozygosity and Y chromosome missingness, that consis

55 nges in genetic diversity (allelic richness, heterozygosity) and the effective number of breeders (N(

56 CA mutant or BRCA wild-type and high loss of heterozygosity), and the intention-to-treat population,

57 of evidence of activating mutations, loss of heterozygosity, and a mass forming proliferation, we pro

58 996 knockouts are strongly enhanced by Notch heterozygosity, and activated nuclear Notch is impaired

59 ony membership, mother-offspring similarity, heterozygosity, and genetic relatedness are all chemical

60 pecific hybridization, high levels of strain heterozygosity, and prion transmission suggest that outb

61 e major genome characteristics such as size, heterozygosity, and repetitiveness.

62 p.Gly374Glu-DLST tumors exhibited loss of heterozygosity, and their methylation and expression pro

63 han one locus, probably driven by absence of heterozygosity (AOH) burden due to identity-by-descent (

64 hich can accelerate cellular transition from heterozygosity (ApcMin/+) to homozygosity (ApcMin/Min) t

65 t the Wrangel mammoth has a 20% reduction in heterozygosity as well as a 28-fold increase in the frac

66 The genome-wide heterozygosity at 9590 genes, all heterozygous in a sing

67 me-wide functional inference of advantageous heterozygosity at cis-regulatory regions.

68 Molecular tumor profiling revealed a loss of heterozygosity at GPR161 in all affected MB(SHH) tumors,

69 Maximal heterozygosity at HLA-I loci ("A," "B," and "C") improve

70 e (including HLA-B*15:01) or somatic loss of heterozygosity at HLA-I was associated with poor outcome

71 Furthermore, loss of heterozygosity at the Chr.16q24.3 locus in breast cancer

72 are haploid, with sex usually determined by heterozygosity at the complementary sex-determining locu

73 line genotype misclassification from loss of heterozygosity at the CYP2D6 locus.

74 r loss of chromosome 22q, leading to loss of heterozygosity at the DGCR8 locus, was found in all 13 s

75 However, loss of heterozygosity at the human leukocyte antigen (HLA) locu

76 sporulate, but if sporulation is disabled by heterozygosity at the IME1 locus, those diploids can ent

77 ditionally, we measured immunocompetence via heterozygosity at the major histocompatibility complex (

78 lective advantage resulting from the loss of heterozygosity at the TP53 locus.

79 HD patients were genotyped for heterozygosity at three SNP sites, before phasing each S

80 enabled the study of haplotype structure and heterozygosities between homologous chromosomes, includi

81 es may be correlated with the maintenance of heterozygosity by mechanisms that rearrange genomes and

82 d with intrinsic noise reduction, regulatory heterozygosity can contribute to the suppression of extr

83 sms between homologous chromosomes, that is, heterozygosity, can influence meiotic recombination path

84 The relationship between CCR5-Delta32 heterozygosity, CCR5 expression, and markers of HIV-1 pe

85 their associated copy number neutral loss of heterozygosity (CN-LOH) were identified by STR and SNP a

86 tions, duplications and copy-neutral loss of heterozygosity (CN-LOH)) on all chromosomes(1,2,5,6,9),

87 , monosomy 7) or copy number neutral loss of heterozygosity (CN-LOH).

88 aberrations (CNAs) and copy-neutral loss of heterozygosity (cnLOH) identified by chromosome genomic-

89 late IHR and associated copy-neutral loss of heterozygosity (cnLOH) in human cells.

90 ng TNFRSF14, but copy-number neutral loss of heterozygosity (CNN-LOH) of this locus was more frequent

91 In summary, maternal DHCR7 heterozygosity, combined with offspring DHCR7 heterozygo

92 nctionality for testing tumors using loss of heterozygosity data or copy number arrays.

93 ssense mutation in one allele and a 'loss of heterozygosity' deletion encompassing the other.

94 rved in tumor phylogenies due to the loss of heterozygosity, deletions, and convergent evolution.

95 Genome-wide heterozygosity does correlate with DNM rate, but only ex

96 Heterozygosity, effective population sizes and gene flow

97 duals diagnosed with CF and SCD, we assessed heterozygosity effects at our lead variants.

98 ith an oncogenic insult, illustrated by Pten heterozygosity, elicited lethal metastatic prostate canc

99 , there was no difference in the variance in heterozygosity estimates, suggesting that some blind ind

100 loci for genotyping efficiency, and compare heterozygosity estimates.

101 Sr50 contained a 2.5 mega-base pair loss-of-heterozygosity event.

102 ncer chemotherapy targeting frequent loss of heterozygosity events is an attractive concept, since tu

103 rmalities, defined as copy number or loss of heterozygosity events that are large and present in only

104 argemouth bass populations had a significant heterozygosity excess, which is likely to indicate a pre

105 ile height is positively correlated with MHC heterozygosity, facial masculinity is not.

106 Heterozygosity-fitness associations were used to explore

107 Using heterozygosity-fitness correlations, we investigated the

108 ance population and (2) estimate genome-wide heterozygosity for 200 individuals.

109 Heterozygosity for a C-terminal truncation, which produc

110 s a common phenomenon and is correlated with heterozygosity for a frequent variant in the 3' untransl

111 erase chain reaction, we identified compound heterozygosity for a maternal splicing variant (chr5:601

112 whole exome sequencing established compound heterozygosity for a non-conservative missense change af

113 tion to date, the functional consequences of heterozygosity for ACTN3 are unclear.

114 orthologous variants and found that compound heterozygosity for all three variants recapitulated the

115 nificant increase in segregation errors, and heterozygosity for an smc1 deletion enhanced this phenot

116 ssels obstructing the bile duct and compound heterozygosity for collagen and calcium-binding epiderma

117 a recessive disorder resulting from compound heterozygosity for deleterious variants of VAC14.

118 Heterozygosity for Engrailed-1 (En1), one of the key fac

119 ities can be genetically separated, compound heterozygosity for functional complementary mutations ma

120 published and revise available estimates of heterozygosity for humans, chimpanzees and horses.

121 family UW-AP exhibited copy-neutral loss of heterozygosity for large portions of the long arm of chr

122 is required for embryonic survival and that heterozygosity for LoF variants of Arhgap29 increases th

123 Lack of difference in heterozygosity for low-frequency variants or disease-ass

124 These neuropathies are linked to heterozygosity for missense mutations in five ARS genes,

125 cEDS can be caused by heterozygosity for missense mutations in genes COL5A2 an

126 utosomal dominant form of the disease due to heterozygosity for missense or nonsense mutations in MYH

127 The mtrm gene is haploinsufficient, and heterozygosity for mtrm (mtrm/(+)) results in high level

128 In a case of SRPS we identified compound heterozygosity for mutations in IFT52, which encodes a c

129 keratosis/ichthyosis, we identified compound heterozygosity for mutations in KDSR, encoding an enzyme

130 o different CRC patient cohorts, we detected heterozygosity for NAT2 alleles targetable by APA, along

131 l anemia with kernicterus caused by compound heterozygosity for null mutations in KLF1, each inherite

132 In subjects with sickle cell trait, heterozygosity for PIEZO1 E756del did not confer additiv

133 Heterozygosity for pol2-P301R is compatible with either

134 ariation in humans and mice, we predict that heterozygosity for R36C, G175R, R17S, and R17H will prov

135 Among the extensive miR-124 target network, heterozygosity for targets in the BMP pathway substantia

136 This study provides strong evidence that heterozygosity for the c.643_663del21 deletion in CAPN3

137 Although heterozygosity for the previously validated human leukoc

138 n of GJB2 encoding connexin (Cx) 26 revealed heterozygosity for the recurrent de novo germline mutati

139 These results indicate that heterozygosity for the wild-type P2X7R and its mood diso

140 Here we sequence the genome of a low-heterozygosity Fraxinus excelsior tree from Gloucestersh

141 iation in at least two ways - by fixation of heterozygosity from diploid progenitors in allopolyploid

142 The expected pattern of heterozygosity from theoretical calculations and simulat

143 expected, the partial contribution to total heterozygosity gave high priority to Criollo pig breeds,

144 has the potential to cause extensive loss of heterozygosity, genetic disease, or cell death.

145 strains in showing slightly higher levels of heterozygosity genome-wide.

146 w-plated alleles has generally increased and heterozygosity has decreased.

147 nonneoplastic proliferation, albeit loss of heterozygosity has long been reported in a part of these

148 ot support the existence of founder effects: heterozygosity (He = 0.667) and allelic richness (Ar = 4

149 hism Information Content; 0.87) and expected heterozygosity (He = 0.79-0.82).

150 ge observed heterozygosity (Ho) and expected heterozygosity (He) in these highly inbred lines were 0.

151 ion in Eswatini was highly diverse (expected heterozygosity [HE] = 0.75) and complex: 67% polyclonal

152 ss 11 datasets in terms of SNP polymorphism, heterozygosity/heterogeneity, diversity indices, concord

153 ns, each accession still possesses extensive heterozygosity, highlighting the inherent differences be

154 The average observed heterozygosity (Ho) and expected heterozygosity (He) in

155 homologous recombination deficiency-loss of heterozygosity/homologous recombination deficiency-large

156 Most regions show significant heterozygosity; homozygosity is largely concentrated to

157 que genetic flatlining that is punctuated by heterozygosity hotspots, enriched for olfactory receptor

158 of epistatic QTL overlap regions of residual heterozygosity identified in the inbred parental parent

159 We observed a decline in heterozygosity in admixed Africans and found that the Eu

160 nges in tissue organisation that result from heterozygosity in Apc, a precancerous situation, are com

161 ed to be associated with significant loss of heterozygosity in breast cancer.

162 Importantly, conditional Mef2c heterozygosity in forebrain excitatory neurons reproduce

163 ergence between parents has been retained as heterozygosity in functionally asexual species, and that

164 quencies of examined L1 insertions indicated heterozygosity in genomes of DLPFC cells.

165 tter health and fitness, and observe greater heterozygosity in healthy-aged individuals.

166 Here, we present loss of heterozygosity in human leukocyte antigen (LOHHLA), a co

167 d ongoing immunoediting, with either loss of heterozygosity in human leukocyte antigens or depletion

168 not reflect immunocompetence measured by MHC heterozygosity in humans.

169 We observe an excess loss of heterozygosity in lung tumors among ATM L2307F allele ca

170 ef2c-Het phenotypes, while conditional Mef2c heterozygosity in microglia reproduced social deficits a

171 ay explain the high incidence of p53 loss of heterozygosity in mutant tumors.

172 me, which are important to identify compound heterozygosity in recessive Mendelian diseases and disco

173 the effect on B-cell function of TACI A181E heterozygosity in reportedly healthy subjects and of the

174 Deepening somatic loss of heterozygosity in serial tumor samples is observed, sugg

175 ers with dominant inheritance due to loss of heterozygosity in susceptible cells.

176 in allelic richness, and showed an excess in heterozygosity in the Cu- and Zn-selected populations co

177 tion, coding SNPs with the highest excess of heterozygosity in the healthy-aged cohort are enriched i

178 variants show significantly higher excess of heterozygosity in the healthy-aged cohort.

179 fied somatic mutations combined with loss-of-heterozygosity in the splicing factor SUGP1 in five of t

180 xual species, and that genome-wide levels of heterozygosity in these asexuals largely reflects the di

181 Mapping the distribution of heterozygosity in these half-tetrad individuals allowed

182 or WGD in tumor types with extensive loss of heterozygosity, including lung squamous cell carcinoma a

183 Ctbp2 heterozygosity increased the median survival of Apc(min/

184 s and the most private alleles, and observed heterozygosity indicates outcrossing.

185 discovered that PRL2 ablation inhibits PTEN heterozygosity-induced tumorigenesis.

186 CHEK2*1100delC heterozygosity is associated with 15% to 82% increased r

187 PODXL heterozygosity is associated with adult-onset kidney dis

188 pressor, and its inactivation due to loss of heterozygosity is associated with cancers of different o

189 Our results demonstrate that the genomic heterozygosity is associated with human healthspan, and

190 we tested the hypothesis that CHEK2*1100delC heterozygosity is associated with increased risk for oth

191 otype, suggesting that susceptibility to En1 heterozygosity is genetically regulated.

192 amino acid changing heterozygosity to silent heterozygosity is higher in dogs than in wolves and, on

193 Along these chromatids, heterozygosity is maximal at the centromeres, and homolo

194 rs and to determine to what extent increased heterozygosity is preserved after genetic recombination

195 Crossover remodeling at homozygosity-heterozygosity junctions requires interference, and non-

196 datasets with a wide range in genome sizes, heterozygosity levels and error rates.

197 imating runs of homozygosity and genome-wide heterozygosity levels are generally sensitive to such li

198 = 0.002), and increased frequency of loss of heterozygosity (LOH) across the genome (median 913 vs. 4

199 els), copy-number variations (CNVs), loss of heterozygosity (LOH) and complex rearrangements, such as

200 g in copy number variation (CNV) and loss of heterozygosity (LOH) are frequently observed during the

201 d-type allele in their tumors due to loss of heterozygosity (LOH) at 8p22.

202 ome (chr) 8p with a common region of loss of heterozygosity (LOH) at chr8p22 locus.

203 with stage III FHWT without combined loss of heterozygosity (LOH) at chromosomes 1p and 16q treated i

204 ithelial cell model and show that 8p loss of heterozygosity (LOH) attenuates the action of several ge

205 tudied the frequency and location of loss-of-heterozygosity (LOH) events on chromosome III in Sacchar

206 housands of non-driver genes undergo loss of heterozygosity (LOH) events per tumor, generating discre

207 Many cancers are initiated by loss-of-heterozygosity (LOH) events that lead to the replacement

208 s (SNPs), copy-number variations and loss-of-heterozygosity (LOH) events.

209 a(m/m);tp53(w/m) zebrafish displayed loss of heterozygosity (LOH) for the wildtype tp53 locus.

210 served point mutations, deletions or loss of heterozygosity (LOH) in beta-2-microglobulin (B2M), an e

211 cific mutations-such as copy-neutral loss of heterozygosity (LOH) in cancer-are missed.

212 occurrence of bursts of genome-wide loss-of-heterozygosity (LOH) in Saccharomyces cerevisiae, provid

213 to 9.53 months]); and BRCA wild-type/loss of heterozygosity (LOH) low patient subgroup (107 rucaparib

214 1 and BRCA2 (BRCA) mutations genomic loss of heterozygosity (LOH) might also represent homologous rec

215 eages revealed a diverse spectrum of loss-of-heterozygosity (LOH) signatures characterized by interst

216 DNA index, chromosome arm 1p or 11q loss of heterozygosity (LOH) status, and symptoms.

217 issue-specific, large copy-number or loss-of-heterozygosity (LOH) variants involving multiple Shh gen

218 he allelic shift signal measures the loss-of-heterozygosity (LOH) which is valuable for CNV identific

219 A2 allele (absence of locus-specific loss of heterozygosity (LOH)) is observed in 7% of BRCA1 ovarian

220 heterozygous deletions, copy-neutral loss-of-heterozygosity (LOH), allele-specific gains/amplificatio

221 s in one TP53 allele are followed by loss-of-heterozygosity (LOH), so tumors express only mutant p53.

222 nt number of copies and copy-neutral loss-of-heterozygosity (LOH).

223 t PDAC cells that have undergone p53 loss of heterozygosity (LOH).

224 rental genome, a phenomenon known as loss of heterozygosity (LOH).

225 fine estimates of continent-wide patterns of heterozygosity, long- and short-distance gene flow, arch

226 The heterozygosity maintained in this experiment allowed for

227 This effect was enhanced for a compound heterozygosity marker constructed from four pre-selected

228 The burden of E161K heterozygosity may be a forme fruste of dRTA.

229 rected for CN in aneuploid regions), loss of heterozygosity, megabase-scale phased haplotypes often s

230 eterozygosity, combined with offspring DHCR7 heterozygosity might represent a vulnerability factor to

231 and losses, and several copy neutral loss-of-heterozygosity mutations at a genome-wide level, includi

232 ch, due to chromosomal deletions and loss of heterozygosity, necessitate the development of inference

233 f wild-type TRPC6 and TRPC6 G757D, mimicking heterozygosity observed in patients, revealed a dominant

234 Haplotypes can be inferred using IGHJ6 heterozygosity, observed in one third of the people.

235 4q32 amplification, and copy-neutral loss of heterozygosity of 9p were gained in the B-LBL cells.

236 Here, we assess the impact of germline heterozygosity of a novel, oxygen-independent ubiquitin

237 Heterozygosity of Atoh1 reduced tumor occurrence and pro

238 parib pretreatment, PARP1 knockdown or Parp1 heterozygosity of Brca2(cko/ko) mouse embryonic stem cel

239 tumors revealed somatic copy-neutral loss of heterozygosity of chromosome 1q as the hallmark characte

240 5 (NWTS-5), tumor-specific combined loss of heterozygosity of chromosomes 1p and 16q (LOH1p/16q) was

241 Subsequent loss of heterozygosity of Dpc4 restores metastatic competency wh

242 Accordingly, compound germline heterozygosity of mouse Sdhb/Sdhc/Sdhd null alleles blun

243 re a hallmark of NF1 and result from loss of heterozygosity of NF1 in Schwann cells, leading to const

244 The tumors did not show loss of heterozygosity of Ptc1, despite high levels of Gli1 and

245 Among those with SHH-MB, loss of heterozygosity of PTCH1 was associated with prolonged PF

246 presentation caused by mutations or loss of heterozygosity of the major histocompatibility complex c

247 Compound heterozygosity of these variants is found at up to 12-fo

248 re, all tumors displayed concomitant loss of heterozygosity of Trp53 and Pten along with frequent amp

249 These data suggest that loss of heterozygosity of TSC1 or TSC2 may play an important rol

250 of KRAS and PIK3CA and mutation and loss of heterozygosity of tumor suppressor genes, such as APC an

251 ver, haplotype divergence in regions of high heterozygosity often results in assemblers creating two

252 The functional consequence of Parp1 heterozygosity on BRCA2 loss is demonstrated by a signif

253 correlations, we investigated the effect of heterozygosity on six diverse fitness measures (ulna len

254 that genetic predisposition to pB-ALL (Pax5 heterozygosity or ETV6-RUNX1 fusion) shaped a distinct g

255 ethnicity (OR: 1.8; P = 0.001) and HFE C282Y heterozygosity (OR: 1.9; P = 0.003) were associated with

256 ly, we did not observe enrichment for P1104A heterozygosity, or for TYK2 I684S or V362F homozygosity

257 fidence interval for the genome-wide rate of heterozygosity outside of such regions from modern genom

258 rected for aneuploidy), regions with loss of heterozygosity, phased haplotypes extending to entire ch

259 slocated tortoises and found that individual heterozygosity predicted tortoise survival, whereas tran

260 or performance status score, age, 1p loss of heterozygosity, presence of oligodendroglial elements, a

261 High levels of heterozygosity present a unique genome assembly challeng

262 f the F(ST) divergence statistic, their high heterozygosities produce greater ancestry inference pote

263 KCNJ2-R67Q mouse was generated and bred for heterozygosity (R67Q(+/-)).

264 rom 6 to 24 per locus, observed and expected heterozygosity ranged from 0.133 to 0.9 and 0.183 to 0.9

265 Heterozygosity ranged from 52-79%, averaging 65.5%, much

266 eristics of a genome, including genome size, heterozygosity rate and repeat content from unprocessed

267 We also find that individual heterozygosity rate is a significant predictor of electr

268 which substantially improves the estimate of heterozygosity rates both genome-wide and for genomic lo

269 s currently available methods for predicting heterozygosity rates for ancient samples.

270 pseudo-diploid yeast genomes with different heterozygosity rates, and real data from human chromosom

271 ic animals can skew estimates of genome-wide heterozygosity rates.

272 polygenic score, runs of homozygosity (ROH)/heterozygosity ratio, distant pedigree computation, and

273 Further, Irf6 heterozygosity reduced Esrp1/2 cleft severity.

274 These studies confirm FLI1 heterozygosity results in pleiotropic defects similar to

275 These results suggest that TACI A181E heterozygosity results in TACI haploinsufficiency with i

276 780CP/Cl-24 cells, which express loss of p53 heterozygosity, retained the p53(V172F) mutation and hig

277 rs12203592, P=1.8 x 10(-27)), MC1R (compound heterozygosity score, P=2.3 x 10(-24)), and RALY/ASIP (r

278 ence in GWAS that assesses only X chromosome heterozygosity, seXY achieved marginally better male cla

279 stricted to neurons by these miRNAs, and its heterozygosity strongly suppresses ectopic peripheral ne

280 ilocus genotype assignment and interspecific heterozygosity suggest incomplete reproductive isolation

281 ing that 509022 had overall higher levels of heterozygosity than HI33.

282 g abnormalities such as copy-neutral loss of heterozygosity that elude other approaches.

283 sion or loss, somatic mutagenesis or loss-of-heterozygosity (the first three also in a tumor-specific

284 Heterozygosity (the Pi*MZ genotype) is a risk factor for

285 total linkage disequilibrium (LD) scores and heterozygosity to construct enrichment scores for improv

286 e find that the ratio of amino acid changing heterozygosity to silent heterozygosity is higher in dog

287 cal-derived DNA samples often underestimated heterozygosity values, in some cases by over 20%.

288 o detects differences in somatic and loss of heterozygosity variants between paired samples.

289 and reciprocal deletions (reciprocal loss of heterozygosity), variations that are significantly enric

290 rrent study investigated whether greater MHC heterozygosity was associated with markers of slower lif

291 ns and to previously published findings, MHC heterozygosity was not related to any of the psychologic

292 Low level of heterozygosity was observed for both SNPs in all populat

293 Heterozygosity was seen in 4/27 (14.8%) mutations, sugge

294 thm, parameter, and biological sequence data heterozygosity, we highlight the need for better measure

295 osomes 13q and 13q, and copy-neutral loss of heterozygosity) were between two and six times less comm

296 ) such aneuploidies have resulted in loss of heterozygosity, where a chromosomal region is represente

297 a germline FAS mutation and somatic loss-of-heterozygosity, which allows comparing the fate of B cel

298 y organism and show large regions of loss of heterozygosity, which we hypothesise to be a short-term

299 ed study of the associations of CCR5-Delta32 heterozygosity with human immunodeficiency virus type 1

300 Sox9 heterozygosity worsens the P30 biliary tree phenotype an