ライフサイエンスコーパス: high

1 ral sites, and rates of DFT1 coinfection are high.

2 development of the visual cortex and remains high.

3 elihood of deleterious interactions is quite high.

4 ase, the mortality of this condition is very high.

5 However, restenosis rates remain high.

6 stream differential expression analysis with high accuracy when applied to the Cancer Genome Atlas da

7 To achieve high accuracy, we performed a large number of expert-bas

8 s the results of unobserved experiments with high accuracy, while making no assumptions about the dyn

9 data to enable data-driven multiplexing with high accuracy.

10 ed internal mRNA m7G sites, a sequence-based high-accuracy predictor, the first web server for assess

11 entative single-atom catalysts, and it has a high activity and selectivity for electrochemical CO(2)

12 Comparative transcriptomics between low- and high-acylsugar-producing accessions of Solanum pennellii

13 s in increased resistance, probably owing to high-affinity binding of SAP2 to pyrethroid insecticides

14 conformational changes in PCSK9 required for high-affinity binding to LDL particles.

15 many biological processes because it builds high-affinity bonds by using several weak binding intera

16 their application in PCR-based diagnostics, high-affinity DNA aptamer generation, site-specific labe

17 ell homeostasis through its recruitment to a high-affinity heterotrimeric receptor complex (IL-2Ralph

18 nimal size (ca. 15-20 amino acids) affording high-affinity lanthanide ion binding, and X-ray fluoresc

19 ng beta2-beta3 loop sequences present in two high-affinity TBPs (K(D) values of 4.2 +/- 0.3 and 3.0 +

20 No association was seen between high aFXa and 90-day clinically relevant bleeding (4.8%

21 ere collected from 285 mothers enrolled in a high-allergy-risk birth cohort, the Melbourne Atopy Coho

22 echanisms, we find that liquid crystals with high anchoring strengths can ensure smooth electrodeposi

23 etry striped phase that is disrupted at both high and low extremes of chemical potential.

24 ion to social mating systems with relatively high and low sperm competition are therefore likely to h

25 In high and medium HIV prevalence settings in South Africa

26 oxygen supply and increasing oxygen demand, high and rising exposure to ultraviolet radiation, low i

27 d southern latitudes, mostly in areas with a high anthropogenic activity.

28 rom 13% in a general population cohort to as high as 78% in patients with inflammatory bowel disease(

29 coding DNVs in a fraction of CHD at least as high as that observed for damaging coding DNVs.

30 dyne imaging (IR-PHI) to interrogate single, high aspect ratio Au nanowires (NWs).

31 Zn anode enables a Zn||Ti cell to achieve a high average Coulombic efficiency of 99.1 % for 350 cycl

32 s, and molecular analyses showed that OXPHOS(high) BAP1 mutant UM cells utilize glycolytic and nucleo

33 In both cell types, promoters with high basal H3K4me2/3 activate in spite of some residual

34 w simultaneous up-regulation of vimentin and high basal Rac1-GTP levels when measured biochemically.

35 f SAE during TPVR in the C3PO-QI registry is high, but mortality is uncommon.

36 , three systems were declining strongly with high certainty (all in the Indo-Pacific region) and seve

37 RSA lineage with huge strain diversity and a high clinical impact.

38 The role of betaCA3 in the high CO(2) -mediated response in tomato and two other So

39 Results showed that KO mice accumulated high concentrations of upstream lysine metabolites inclu

40 Moreover, even when a high concordance about the relevance of one parameter wa

41 We observed high concordance rates between our platform and other ge

42 HEK293 genomic DNA, resulting in a set of 55 high-confidence gRNA cleavage sites identified by both m

43 r routes to produce methane with high FE and high conversion rate in CO(2)RR and also make direct use

44 produce such ceramic NWs have prohibitively high cost.

45 ee film growth while maintaining epitaxy and high crystal quality.

46 Strikingly, we observed very high currents of tens of nanoamperes, which flowed throu

47 Among individuals with high CVH, event rates were low across sociodemographic s

48 Those with high cycle threshold are unlikely to have infectious pot

49 With the possibilities of high data acquisition speed or high separation powers in

50 ver-three" splitting of the d-orbitals and a high degree of metal-ligand covalency due to metal -> li

51 nd surface proteins of erythrocytes showed a high degree of variability in display of modified Sia be

52 To achieve a high dendrite-suppression capability, SSEs should be the

53 bstantial proportion of these SINEs harbor a high density of the enhancer-specific histone mark H3K4m

54 ) is limited by a spatial disconnect between high-density wetland areas and N hotspots.

55 the echocardiographic parameters agreed and high discordance when 3 or 4 parameters were discordant.

56 ance, to aggressive and invasive tumors with high disease-specific mortality.

57 The high diversity microbiota, Community State Type IV-B, wa

58 ectories and reduced their variance, whereas high-dose AMPH expanded both.

59 the risk of, and associations with, SAE and high-dose radiation exposure using large-scale registry

60 Withdrawal of VKAs and high-dose vitamin K2 improve vitamin K status in patient

61 The present findings also revealed that high doses of BrdU lead to the activation of apoptotic c

62 ated ICU patients who were given moderate-to-high doses of opioids and expected to remain alive and v

63 Results: Each radioligand gave high early whole-brain uptake of radioactivity, followed

64 cular patterns (DAMPs/PAMPs) from blood with high efficiency (92-99%).

65 ucting electrode (TCE) properties, including high electrical conductivity (~11 670 S cm(-1) ) and hig

66 llenges and interactions among challenges in high-elevation streams, which include low but rising tem

67 sociated Hg-S(3)/S(4) species, as studied by high energy-resolution X-ray absorption near edge struct

68 Our study shows that at high enough cell concentration the interaction between b

69 ly, the LPL-GPIHBP1 fusion protein exhibited high enzyme activity in in vitro assays.

70 ey injury (AKI) and the risk of mortality is high, especially if renal replacement therapy is needed.

71 Here we demonstrate that, in regions of high exchange energy density, skyrmions may exhibit such

72 were expressed in the esophageal gland with high expression during the parasitic stages of nematode

73 infected with T. gondii, as associated with high expression level (P <= 0.001) of Peak # 15 (2 x Neu

74 We find that high-expression clones carry insertions that are not cor

75 a simultaneous high NH(3) formation rate and high Faradic efficiency (FE) difficult.

76 High-fat diet (HFD)-induced inflammation and steatosis o

77 skeletal muscle adaptions to training during high-fat diet.

78 ior were also normal, even after exposure to high-fat diet.

79 ective effects on glucose homeostasis during high-fat overfeeding.

80 We find that short-term high-fat-diet (HFD) feeding of mice activates prepronoci

81 indings offer routes to produce methane with high FE and high conversion rate in CO(2)RR and also mak

82 hazard ratio, 0.61 [95% CI, 0.44-0.83]) and high fit (tertile 3: hazard ratio, 0.38 [95% CI, 0.24-0.

83 es were detected on 5 (of 12) chromosomes in high-fitness individuals of both reciprocal crosses, whe

84 f proteins showed high intensities, while at high flow rates, ions related to higher charge states of

85 M-MDSCs remained high for 1 y posttransplantation.

86 ay excellent photophysical properties with a high fraction of long-lived charge carriers and the avai

87 t supports reliable synaptic transmission at high frequency in the CNS.

88 and information theoretic characteristics of high frequency LFP before and after local seizure invasi

89 minals of juvenile mice of either sex during high-frequency spiking.

90 ton campus with two populations sourced from high (Gatton) and medium (St George) rainfall areas of t

91 gimens could reduce this threat due to DTG's high genetic barrier to resistance.

92 ain comparable genetic diversity but display high genetic differentiation, a potential consequence of

93 , which mimic the diabetic milieu, including high glucose and/or fatty levels, and by the ablation of

94 l G6P but not ATP and decreased G6pc mRNA at high glucose.

95 oxicity tables that include the incidence of high-grade adverse events, defined by the Common Termino

96 ti-gammaH2AX-TAT localizes preferentially in high-grade PanIN lesions but not in established PDAC.

97 present study, we report the production of a high-grade spinal cord glioma model in pigs using lentiv

98 mphovascular invasion, hydronephrosis and/or high-grade upper tract disease(3-5).

99 ients with cerebral gliomas (9 low-grade, 34 high-grade; 9 primary tumors, 34 recurrent tumors) who h

100 aces was found to proceed rapidly leading to high grafting densities, while o-methylbenzaldehyde func

101 is challenging because of low bacterial and high human DNA abundances.

102 TOR inhibitors (mTORi) should not be used in high-immunological risk kidney transplant recipients due

103 confirmed COVID-19 infection rates have been high in the United Kingdom.

104 onists, and categorized as "high-in" or "not high-in" according to whether they contained high levels

105 a team of nutritionists, and categorized as "high-in" or "not high-in" according to whether they cont

106 n Africa (2.76 per 100 women), compared with high-income countries like the United States (1.69 per 1

107 ite race, older age, higher body mass index, high-income region of enrollment, hypertension, and teno

108 Currently, low gasoline prices and high initial expense means that, without subsidies, few

109 ates, lower charge states of proteins showed high intensities, while at high flow rates, ions related

110 educed behavioral reaction time latencies to high-intensity sounds.

111 through a phenomenon called sonoporation by high-intensity ultrasound and microbubbles or cavitation

112 Most respondents (61%) expressed high interest in genetic testing as a PLD: age >=35 year

113 Es should be thermodynamically stable with a high interface energy against Li, and they should have a

114 Additionally, the high intra-observer and inter-observer variability in gr

115 uld have a low electronic conductivity and a high ionic conductivity.

116 From 832 high-LD variants, we identify 39 candidate functional va

117 m DCLK1-overexpressing hepatoma cells showed high level expression of active beta-catenin, alpha-feto

118 nderstand whether SMC continues to provide a high level of protection and how SMC might be improved.

119 d by those patterns transitioned from low-to-high level properties.

120 Using high-level first-principles simulations of all critical

121 in (the "eat me" signal for macrophages) and high levels of CD47 (the "do not eat me" signal for macr

122 hin the BRB/BBB are tightly coupled, express high levels of Claudin-5 (CLDN5), a junctional protein t

123 droboration of 1,1-disubtituted alkenes with high levels of enantioselectivity, even when the two sub

124 Paradoxically, despite the high levels of Env on the surface of MT-4 cells, 2-fold

125 deal to examine this topic because they show high levels of leg loss in the field but do not regenera

126 high-in" according to whether they contained high levels of nutrients of concern (i.e., sugars, sodiu

127 by expression of FcgammaRIIIA (CD16) and by high levels of proinflammatory cytokine secretion and cy

128 echnology to prevent drowsy driving suggests high levels of readiness and acceptance for such interve

129 High levels of skeletal muscle sensory feedback related

130 were terminally differentiated and expressed high levels of the NKG2C ligand HLA-E.

131 Fermented avocado puree resulted in high levels of total free amino acids.

132 se cells, which express both RB and S18-2 at high levels, exhibited the potential to differentiate in

133 oods, wean early, mature slowly, and exhibit high lifelong investments in maintenance.(3-6) These ada

134 Switching mice to a high lysine/low PN diet led to vigorous seizures and a q

135 High magnification SEM images show that the thin film is

136 Additionally, high-mannose-binding lectins possess a broad capacity to

137 A high mass activity (1.946 A mg(-1) at 0.45 V) of Pd(delt

138 (HR-XANES) spectroscopy, under conditions of high MeHg production (with Cys addition).

139 LD and DQI sub-groups, with the exception of high MELD patients transplanted with "high-risk" grafts.

140 It also shows high metabolic stability in all species, linked to an ad

141 during the global re-methylation phase have high methylation levels prior to global de-methylation,

142 the intracellular [Ca(2+)] ([Ca(2+)](i)) and high-molecular-weight glycoprotein secretion.

143 e dominant, endemic(6-8) and associated with high mortality(6,9,10).

144 early diagnosis is an important cause of its high mortality.

145 NA polymerase epsilon (POLE) have incredibly high mutation burdens.

146 ssociated significantly with both myopia and high myopia (OR, 2.43 and 2.31).

147 ignificant challenges, making a simultaneous high NH(3) formation rate and high Faradic efficiency (F

148 genes, with a method able to handle both the high number of interacting variables and the noise in th

149 del, mice clustered in two groups displaying high or low clinical scores.

150 s only under specific physical conditions of high or low temperature or high pressure.

151 pounds containing such a salt bridge reached high oral bioavailability and oral exposure.

152 nalogues (RX, NaHCO(3)/DMF/100 degrees C) in high overall yields.

153 ising targets in cancer therapy due to their high overexpression on cancer cells and their ability to

154 including cerebral malaria (CM), driven by a high parasite load, leading to parasite sequestration in

155 acellular parasite research is collection of high parasite numbers separated from host contamination.

156 ECG and myopotential, it is possible to use high-pass or band-pass filtering to specifically isolate

157 At high peptide concentrations in the membrane, the (19)F-(

158 e application of this method in a fast ultra-high performance liquid chromatography (UHPLC) analysis

159 pollination time as well, which demonstrated high performance of the metabolic fingerprinting and rev

160 ptors (NFAs) with crystalline domains enable high-performance bulk heterojunction (BHJ) solar cells.

161 structures enhances the capability to design high-performance ion-regulating devices and promotes the

162 nd lipids were extracted and fractionated by high-performance liquid chromatography (HPLC).

163 design guidelines for the next generation of high-performance n-type materials for thermoelectric app

164 ay for practical large-scale applications of high-performance SDRC for human thermal comfort in build

165 fibers, it would be possible to compete with high-performance synthetic fibers such as glass fibers a

166 All these properties translate to high-performance X-ray imaging with sensitivity up to 17

167 ocessed metal oxide films and the promise of high-performance, ultra-stable metal oxide semiconductor

168 ship between alternating stereochemistry and high permeability, as well as a set of highly permeable

169 tron microscopy structures of human PAC in a high-pH resting closed state and a low-pH proton-bound n

170 Identifying field pea cultivars with high phosphorus use efficiency (PUE) is highly desirable

171 point to CN changes that are more common in high-ploidy tumors and thus support altered selection pr

172 89%, and 85% in EVOOs with low, medium, and high polyphenolic levels, respectively, with the highest

173 ce and refractory materials characterized by high porosity (70-75%) and low bulk strength (10(-4)-10(

174 entification of novel GSK3beta inhibitors of high potency and specificity.

175 w-energy attenuation and patch antennas with high-power radiation at frequencies from 5.6 to 16.4 GHz

176 A prenatal sex steroid environment of high prenatal testosterone and low prenatal oestrogen in

177 cal conditions of high or low temperature or high pressure.

178 Board of Trustees believes that myopia is a high-priority cause of visual impairment, warranting a t

179 However, the high processing temperatures prevent growth of other Jan

180 ase region" has low sequence complexity, has high proline content, and lacks predicted secondary stru

181 Bact2 is characterized by a high proportion of Bacteroides, a low proportion of Faec

182 hen phage infections occur on solid media, a high proportion of the surviving colonies display comple

183 These approaches frequently propose high proportions of nonforming or noninfective capsid pr

184 This device exhibits a high proton conductivity, fast response time, and extrem

185 Additionally, due to the high qualifying limit of 45Q for the power sector, e.g.,

186 y reducing the capacity of nurses to provide high quality care.

187 in the ovine Y chromosome isolation and the high quality of the Y chromosome sequences.

188 for wheat flour in producing sponge cakes of high quality.

189 ell-being; and (5) improve patient access to high-quality cancer care via telemedicine.

190 (1) promote and protect equitable access to high-quality cancer care; (2) support safe delivery of h

191 ty cancer care; (2) support safe delivery of high-quality cancer care; (3) advance policies to ensure

192 healthcare environment while still providing high-quality care to a large cohort of patients with hea

193 Although conventional homoepitaxy forms high-quality epitaxial layers(1-5), the limited set of m

194 ary, our yeast-display-based platform yields high-quality MHC-II-binding peptide datasets that can be

195 oviders have sufficient resources to provide high-quality patient care; (4) recognize and address thr

196 nly leads to good results when combined with high-quality structures, whereas it can even be detrimen

197 anical exfoliation has been a key to provide high-quality two-dimensional materials, but despite impr

198 s, the hazard ratios for CRC incidence after high-quality versus low-quality colonoscopy were 0.55 (C

199 This revealed 44,652 high-quality viral genomes (that is, >90% complete), alt

200 (203)Pb-L1-(203)Pb-L5 were synthesized in high radiochemical yield and specific activity.

201 nsplant dialysis treatment in a state with a high rate of dialysis mortality are at a higher risk for

202 The high rates of 2 or 3 treatment modifications over the 4-

203 th tetralogy of Fallot and an ICD experience high rates of appropriate therapies, including those imp

204 interpretation of mammograms is affected by high rates of false positives and false negatives(2).

205 The response of mangroves to high rates of relative sea level rise (RSLR) is poorly u

206 To explain the basis for the extraordinarily high recurrence rates of UTIs, we examined adaptive immu

207 e subunit was constructed with exceptionally high regio- and stereoselectivities.

208 High-resolution analyses of these two types of QTLs reve

209 High-resolution chromosome conformation capture (Hi-C) a

210 In summary, definition of high-resolution enhancer boundaries enables deconvolutio

211 ed on green fluorescent protein (GFP) enable high-resolution imaging of dopamine dynamics in behaving

212 Our study provides a high-resolution map of eRNA loci through which super-enh

213 We used HiCorr to compare the high-resolution maps of chromatin interactions from 10 t

214 oextraction (SPME) fiber, and the inlet of a high-resolution mass spectrometer is described.

215 e wide-isolation quantitative strategies for high-resolution mass spectrometry (HRMS) combined with p

216 benzoylbenzodipyrroles were characterized by high-resolution mass spectrometry (HRMS), NMR, and X-ray

217 Ultrahigh-performance liquid chromatography high-resolution mass spectrometry (UHPLC-HRMS) supported

218 resented method showed a stable baseline and high-resolution separation of the standards.

219 is entering an exciting time where many new high-resolution structures of large complexes and membra

220 Using high-resolution synchrotron radiation microtomography (S

221 Here, we apply a high-resolution, pressure-based approach to describe how

222 dvantage of sheathed flagella bundles is the high rigidity, making high swimming speeds possible.

223 italization for HFpEF identifies patients at high risk for near-term clinical progression.

224 racranial stenosis was perceived to convey a high risk of recurrent stroke, but two previous trials (

225 Patients at clinical high-risk (CHR) for psychosis show elevations in [(18)F]

226 ulopathy in patients of African ancestry and high-risk APOL1 genotype infected with SARS-CoV-2 have e

227 levated anxiety symptoms in combination with high-risk biological factors such as APOEepsilon4 and su

228 Our findings show that the known high-risk CNVs are not only associated with schizophreni

229 t is associated with increased prevalence of high-risk coronary plaque and risk of cardiovascular eve

230 lications in PCOS should focus on women with high-risk features rather than all women with PCOS.

231 High-risk features were defined by bulky tumors, variant

232 valve intervention improves outcomes in this high-risk group.

233 pathology, with an increasing occurrence of high-risk ICI-related myocarditis.

234 early phase clinical trials in children with high-risk MYCN-driven disease, with limited ability to e

235 ance mechanism (TMM) on clinical outcomes in high-risk neuroblastoma, we integrated the C-circle assa

236 ) are being used to rule out infection among high-risk persons, such as exposed inpatients and health

237 reexposure prophylaxis (PrEP) regimens among high-risk populations, including men who have sex with m

238 ES) to correct for intravascular deficits in high-risk surgical patients is either effective or safe.

239 ion of high MELD patients transplanted with "high-risk" grafts.

240 Remarkably high risks for second in situ squamous cell carcinoma of

241 omatic slide loader automates 3D imaging for high sample-throughput.

242 /through high-school education, 1.00; beyond high-school education, 0.61).

243 6; Blacks, 0.90; Whites, 0.50; up to/through high-school education, 1.00; beyond high-school educatio

244 The assay allowed a rapid and high-sensitive C. acutatum detection mean, being able to

245 A CDG with high sensitivity was derived and validated.

246 sibilities of high data acquisition speed or high separation powers in combination with the increased

247 ism (SNP)-trait associations, which leads to high sequencing cost.

248 for BSA-Seq data analysis require relatively high sequencing coverage to detect significant single nu

249 operative events occurred more frequently in high-severity versus low-severity cases (0.98 vs 0.40 ev

250 In the intertidal zone, high-shore environments experience more environmental fl

251 re highly polar functional groups leading to high solubility and metabolic stability but occasionally

252 Here, using high spatial and temporal resolution live-cell microscop

253 ic corals capable of growing microalgae with high spatial cell densities of up to 10(9) cells mL(-1).

254 sive mcfDNA-Seq had moderate sensitivity and high specificity, NPV, and PPV for pulmonary IMI after H

255 We recently developed high-speed single-point edge-excitation sub-diffraction

256 High spinal fluid protein was found in 27/32 (78%) cases

257 The high stability observed with the modified electrode for

258 erence between cv HI10 and cv Spence was the high steady-state level of K(+) in cv HI10.

259 The high stereoselectivity of the reaction is attributed to

260 e film endow the robust protective skin with high stretchability.

261 nown function with low sequence homology but high structural homology to both yeast Get2 and mammalia

262 lagella bundles is the high rigidity, making high swimming speeds possible.

263 Despite these high systemic ROS levels, stomatal aperture size returns

264 of SLG1 enhances the tolerance of plants to high temperature.

265 ins a formidable challenge, especially under high-temperature conditions.

266 the region of the trimeric serine hydrolase high-temperature requirement 1 (HTRA1) are associated wi

267 nets are excellent candidates owing to their high-temperature stability.

268 attention after a theoretical prediction of high thermoelectric figure of merit, zT > 2.

269 e in a fast (less than 1 min per sample) and high-throughput (up to 384 samples per run) way.

270 In summary, the platform affords high-throughput analyses of antibodies, including bispec

271 ia are inefficient, and often prevent rapid, high-throughput analyses.

272 within seconds, holding great potential for high-throughput analysis.

273 Combining high-throughput discovery and subsequent structure-funct

274 s and development of improved mixture-based, high-throughput drug discovery techniques.

275 were obtained from 16 055 datasets using 12 high-throughput experiment methods (e.g. H3K4me1/H3K27ac

276 tered and water-limited growth conditions, a high-throughput phenotyping facility was used to measure

277 A high-throughput platform would greatly facilitate corona

278 generation of more physiologically relevant high-throughput screens (HTS).

279 an inducing pseudouridylation of the miRNAs, high-throughput sequencing crosslinking immunoprecipitat

280 High-throughput sequencing experiments followed by diffe

281 combines chromatin conformation capture with high-throughput sequencing.

282 sources can be implemented in many different high-throughput settings to ultimately improve power.

283 technology to develop multiple all-inclusive high throughputs and customized organ-on-a-chip-like pla

284 The immunologic study revealed high titers of IgG autoantibodies in serum and cerebrosp

285 h yields, high volumetric productivities and high titers.

286 d with coexisting actionable mutations and a high TMB.

287 cancer, but is limited by short exposure and high toxicities.

288 Expanded GPA33(high) Treg cells are suppressive, unable to produce proi

289 A high tumour mutational burden (hypermutation) is observe

290 nging C(sp(3))-OC(sp(3)) bond formation at a high-valent nickel center to proceed in good yields whil

291 male rats were trained to exert effort for a high-value reward (sucrose pellets) in a progressive rat

292 ugars into biofuel will require high yields, high volumetric productivities and high titers.

293 ate hypersaline solutions with exceptionally high water flux (and throughput), single-pass water reco

294 h late presentations, the mortality rate was high, whereas frequencies of LVRR and LV full recovery w

295 ortality in ICU-admitted stroke patients was high with 30 days mortality of 31% in ischemic stroke an

296 ent satisfaction with breast appearance were high with either no difference or better outcome in the

297 s in S. pneumoniae and other bacteria drives high within-host pneumococcal genetic diversity.

298 ctrical conductivity (~11 670 S cm(-1) ) and high work function (~5.1 eV), which are achieved by comb

299 ising sustainable intensification options in high-yielding cereal systems.

300 ass-derived sugars into biofuel will require high yields, high volumetric productivities and high tit