ライフサイエンスコーパス: high expression

1 cterized both by elevated H3.3 occupancy and high expression.

2 ouse spleen, defined by cKit(+)CD71(low)CD24(high) expression.

3 pecimens stained positive for podoplanin (33 high expression, 47 medium expression, 71 low expression

4 t stabilize mRNA secondary structure enabled high expression across a wide variety of primary sequenc

5 The high expression across multiple tumor types and restrict

6 High expression and activation of EGFR and/or ErbB2 were

7 o natural duplicates sampled from genes with high expression and identified outlier samples with a 2-

8 CI-60 lung carcinoma cell lines, valine with high expression and isoleucine with low expression.

9 hine learning models to discriminate between high-expression and low-expression genes, focusing on th

10 promoters of highly amplified genes showing high expression, and with somatic single-nucleotide vari

11 Genes with high expression at baseline in fresolimumab nonimprovers

12 ATA3 in neuroblastoma, which correlated with high expression at both the RNA and protein level.

13 prostate cancer is spatially biphasic, with high expression at the invasive front, correlating with

14 We find that high-expression clones carry insertions that are not cor

15 suppressor gene role may be real, while its high expression correlating with worse end-point outcome

16 The results show particularly high expression during the first few hours of developmen

17 were expressed in the esophageal gland with high expression during the parasitic stages of nematode

18 We found uniformly high expression for these mutants and excellent reaction

19 The Mon/Mac cells were also shown to have high expression for TNFalpha but not IL-17A.

20 In total, 291 hypomethylation-high expression genes and 168 hypermethylation-low expre

21 ally significant differences between low and high expression groups (p < 0.0001).

22 ers have prognostic capability by indicating high-expression groups have higher chance of survival co

23 ps have higher chance of survival compare to high-expression groups.

24 Furthermore, it is unclear how the high expression impacts global translation.

25 The glucose transporter 1 (GLUT1) with high expression in cancer cells was approved to be invol

26 cer chemotherapy is increased in view of its high expression in cancer stem cells, a population of ca

27 THEMIS, a T cell-specific protein with high expression in CD4(+)CD8(+) thymocytes, has a crucia

28 centas, we found that both genes demonstrate high expression in first- and second-trimester placenta,

29 e expression profiling identified genes with high expression in human but not in bovine fibroblasts.

30 Despite its high expression in immune cells, the effect of c-Cbl on

31 t overlapping pattern of expression; GHR had high expression in liver and heart tissues, whereas PRLR

32 scopy and flow cytometry analysis, showing a high expression in macrophages, T cells, and fibroblasts

33 Periostin is a glycoprotein with high expression in many tumors of epithelial origin incl

34 but not for neuronal development despite its high expression in neurons.

35 rain at 16-18 weeks post-conception revealed high expression in radial glial cells, compatible with a

36 tected mostly in the tumor cell nuclei, with high expression in some mitotic cells.

37 In addition to high expression in the brain, we report for the first ti

38 chimpanzees and macaques and that genes with high expression in the DMN are involved in synapse and d

39 ATEMENT The alpha5-GABA(A)R subunit exhibits high expression in the hippocampus, and regulates the in

40 ng PIM1 as a putative resistance gene, whose high expression is associated with high-risk disease and

41 erexpressed in CRC patient specimens and the high expression is correlated with poor patient survival

42 t options for FGFR4-positive patients, whose high expression is not caused by mutation or amplificati

43 nt of the underlying disorder, and that this high expression is sufficient to drive constitutive phos

44 infected with T. gondii, as associated with high expression level (P <= 0.001) of Peak # 15 (2 x Neu

45 A typical feature of astrocytes is their high expression level of connexin43 (Cx43), a protein fo

46 A high expression level of EphA2 predicts poor prognosis,

47 Simultaneously, high expression level of IL-6R mRNA correlates with bett

48 ree alleles per cell were induced, a sign of high expression level.

49 E. ulmoides exhibits high expression levels and/or gene number expansion for

50 3G123500 and Glyma.13G194400 with relatively high expression levels at seed development stage compare

51 on increases as cancers progress, leading to high expression levels in high-grade tumors and metastas

52 We suggest that because of high expression levels in striated muscle, TRIC-A produc

53 Finally, we showed that high expression levels of both CD24 and CD44 were associ

54 -cell RNA-seq analysis of murine BC revealed high expression levels of cholinergic and bitter taste s

55 In colorectal adenocarcinomas, high expression levels of genes encoding CEACAM proteins

56 GLS1 expression in HNSCC, and patients with high expression levels of GLS1 experienced shorter disea

57 Owing to the high expression levels of HER2, combination therapies ar

58 rotein clients, which when combined with the high expression levels of Hsp proteins (2%-6% of total p

59 Interestingly, the high expression levels of Iso4/4b observed both at visit

60 tological analysis of tumor tissues revealed high expression levels of key mediators that were identi

61 to the more competitive G. androsaceus with high expression levels of keystone functional genes.

62 Notably, the survival rate for the high expression levels of Lrp5, CSF1, and CD105 in tumor

63 Targeting Notch1 in cancers that harbor high expression levels of Notch1 offers an addition to t

64 We show that high expression levels of p38alpha correlate with poor s

65 s compared with CD8+ T cells, with initially high expression levels of PD-1 and CTLA-4 that were asso

66 High expression levels of PUMA are correlated with decre

67 However, high expression levels of SFRP1 protein were correlated

68 ventions specifically activated regions with high expression levels of the dopamine receptors D2 and

69 entions predominantly activated regions with high expression levels of the dopamine receptors D2 and

70 hrough a large enhancer domain, resulting in high expression levels of the oncogene required for tumo

71 At high expression levels, APOL1-G0, -G1, and -G2 inserted

72 d-chain amino acid aminotransferase (BcAT)'s high expression levels, respectively.

73 OBPs and CSPs showed very high expression levels.

74 a particularly steep, nonlinear increase at high expression levels.

75 eckles, with chromosome regions of unusually high expression located at the apex of chromosome loops

76 rns that the results were determined only by high expression, non-barcoded genes.

77 ional and dysfunctional PF mutants developed high expression nongenetically, which then diminished, a

78 High expression of 11 complement genes was linked to unf

79 High expression of 2',5'-oligoadenylate synthetase 1 (OA

80 ing the intronic multimerized enhancer drove high expression of a betaGeo reporter in chondrocytes, b

81 l signatures in patients, grouped by low and high expression of a splice variant associated with pati

82 Human cell lines with high expression of a target, determined through a proteo

83 lar signature of adenosine and ECM profiles; high expression of A(2B) adenosine receptors correlated

84 elevated rates of protein synthesis and that high expression of ABCE1, a translation factor directly

85 ant meristems, with low mitotic activity and high expression of abscisic acid response genes.

86 earance of ACs; such characteristics include high expression of AC recognition receptors, low express

87 Adipose tissue demonstrates high expression of ACE2 which SARS- CoV-2 exploits to en

88 Nucleated erythroid cells had high expression of ACKR1, which facilitated their direct

89 Despite high expression of ACT, the rseA mutant strain did not i

90 ironment reduced the number of CD8 TILs with high expression of activating/inhibitory receptors PD-1

91 istics, including a distinct BCR repertoire, high expression of AID, high sensitivity to PAMPs, and t

92 rentiation capacity of BMSC was greater with high expression of alpha-SMA and NG2 positive cells.

93 metabolic sensor mTORC1, indicating that the high expression of amino acid transporters induces amino

94 A high expression of antiangiogenic factors leads to the l

95 Nrf2 protective role was associated with high expression of antioxidant genes (ho-1, gclc, nqo1..

96 Patients with high expression of AURKA were associated with shorter ov

97 High expression of AXL in melanoma cells is associated w

98 Given that high expression of B-Myb correlates with global loss of

99 activity of mitoBK(Ca) was accompanied by a high expression of BK(Ca) transcript in the BK-beta1 KO,

100 We also demonstrated that high expression of BMI1 is critical for the development

101 e samples from breast cancer patients, where high expression of both BCAR4 and YAP is associated with

102 Because high expression of both CD39 and CD73 ectonucleotidases

103 ombination of FUT1 and B3GALT5 revealed that high expression of both genes had poorer RFS and OS than

104 sal-like PDXs, cell lines, and patients, and high expression of both genes reduces metastasis-free su

105 High expression of both IL7R and IL-7R signaling signatu

106 layer V cortical neurons retains relatively high expression of both NEEP21/Nsg1 and P19/Nsg2 at post

107 High expression of both PINCH-1 and myoferlin correlates

108 High expression of CCAR2 correlates with poor outcomes i

109 CCR7 surface expression was associated with high expression of CCR5, which keeps DC in inflamed peri

110 Because high expression of CD11d was detected in several inflamm

111 For four consecutive weeks, high expression of CD137L by a K562-derived aAPC cell li

112 ident macrophages (BMRMs) characterized by a high expression of CD163 and functionally distinct from

113 Studies in mice have linked high expression of CD26 to a profibrotic fibroblast phen

114 High expression of CD31, which indicates presence of mor

115 e epithelial compartment was correlated with high expression of CD4 and ICOS in the stromal compartme

116 tumor sites and metastasis cancer cells with high expression of CD44.

117 on protein were linked to resistance, as was high expression of cell cycle gene signatures after trea

118 ation along with a transcriptomic profile of high expression of combined proinflammatory and profibro

119 CRLM with high expression of consensus molecular subtype-4 identif

120 Here, we report that high expression of CRIPTO correlates with poor survival

121 Additionally, the high expression of CSF1R on tumor cells has been associa

122 High expression of CtBP and low expression of SREBF2 and

123 Functionally matured NK cells with high expression of CX3CR1, HAVCR2 (TIM-3), and ZEB2 repr

124 AS(*)-mediated repression of IRF2 results in high expression of CXCL3, which binds to CXCR2 on myeloi

125 In clinical samples, ESCC patients with high expression of CXCR7 and IL6 presented a significant

126 ends on CDK2 degradation and correlates with high expression of cyclin E1 (CCNE1), which functions as

127 ial electron transport in DS cells is due to high expression of cystathionine-beta-synthase (CBS) and

128 osteosarcoma tissue microarray we identified high expression of cytoplasmic p27 in metastatic tumors.

129 We have demonstrated for the first time high expression of D2 dopamine (DA) receptors in CD133+v

130 ells can be identified in mice and humans by high expression of DNGR-1 (also known as CLEC9A), a rece

131 ogenesis phenotypes, we observe particularly high expression of ECT2, ECT3 and ECT4 in rapidly dividi

132 High expression of either FUT1 or B3GALT5 was significan

133 High expression of either S100A2 or S100A4 was independe

134 High expression of EN1 correlated with short overall sur

135 transcription of 41 of these 59 genes, with high expression of EPSPS, as well as genes coding for am

136 ERAS formed by chromothripsis and leading to high expression of ERAS, a constitutively active RAS pro

137 EAC gene expression patterns, we associated high expression of ERBB3 with an epithelial gene express

138 liver-adapted TRM, including their signature high expression of exhaustion markers PD-1 and CD39.

139 High expression of FABP3 and CD36 were associated with s

140 Furthermore, Id3(-) eT(R) cells have high expression of functional inhibitory markers and a t

141 High expression of GABPB1-AS1 was correlated with a poor

142 s expressed by 66% of PDAC samples analyzed; high expression of genes associated with metabolic adapt

143 was increased in old BM, and they exhibited high expression of genes encoding inflammatory cytokines

144 We propose that the high expression of genes involved in the persistently ac

145 They are characterized with high expression of genes related to Notch signalling, TG

146 ays genes in AF cells, while NP cells showed high expression of genes related to the protein synthesi

147 We observed high expression of GPC-1 in more aggressive prostate can

148 ofibroblasts and the second characterised by high expression of growth factors and immunomodulatory m

149 Moreover, high expression of GSDMC correlates with poor survival.

150 Furthermore, we found that high expression of H-RasV12 abolished this mechanism and

151 marker analyses suggested that patients with high expression of hepatocyte growth factor or unmethyla

152 High expression of HMGB1 was associated with MVD and poo

153 Arabidopsis thaliana with low, wild-type and high expression of HOL1 methyltransferase previously sho

154 eloid leukemia genetic sub-types converge on high expression of HOX genes, critical for their self-re

155 anti-PD-L1 immunotherapy, and patients with high expression of HPV16 E5 had worse survival.

156 Our investigation links high expression of HSATII RNA to the DNA damage response

157 most pronounced the DMN, runs parallel with high expression of human-accelerated genes (HAR genes).

158 LUAD cohorts from TCGA and SPORE showed that high expression of Id1 was a marker of poor survival in

159 ted with improved survival (p = 0.009) while high expression of IDO1 or CD47 in the malignant cells w

160 deficient Treg cells were unable to maintain high expression of IL-2Ralpha, resulting in impaired IL-

161 ferons juxtaposed to elevated chemokines and high expression of IL-6.

162 shows a significant association between the high expression of IL1beta and high D. nodosus load in f

163 le tumor immune microenvironment, as well as high expression of immune check point molecules.

164 rovement in multiple studies suggesting that high expression of immune-related genes indicates active

165 l-to-cell heterogeneity leading to uniformly high expression of individual rDNA in single cells.

166 nctions of antibody and cytokine production, high expression of inhibitory receptors and distinct tra

167 show progressive loss of effector functions, high expression of inhibitory receptors and distinct tra

168 of AXL in melanoma cells is associated with high expression of invadopodia components and an invasiv

169 A high expression of IPs renders monocytes susceptible to

170 ol of the human IRF6 enhancer element showed high expression of IRF6 in major and minor salivary glan

171 Moreover, the high expression of ISGs was associated with significantl

172 -translational control of its activation and high expression of its inhibitors in the gut, measuremen

173 ssivity of RNA polymerase II to maintain the high expression of key genes (including Hoxa9 and Hoxa10

174 Memory-like CD4(+) T cells had high expression of Ki-67, indicative of cell division, a

175 Importantly, high expression of Kv1.3 correlated with high Ki-67 and

176 e spa1-1 mutation resulted in constitutively high expression of LHCSR and PSBS RNAs in both low light

177 ic transmembrane protein marker (TM7318) and high expression of lipopolysaccharide-induced tumor necr

178 We also find evidence for high expression of low-voltage activated Ca(2+) channels

179 High expression of LRRK2 and its substrate Rab10 occurs

180 ar extracellular matrix (ECM) components and high expression of lysyl oxidases.

181 in HSPC-derived cells, which show aberrantly high expression of m1 and m3 under androgen deprivation

182 High expression of MAP4K1 (which encodes HPK1) correlate

183 which catabolic remodeling, associated with high expression of metallopeptidase-7, -9, and -12, dive

184 In human LA samples, we found high expression of MHC-II in tumor cells of AT-II cellul

185 High expression of miR-30a or miR-200c was associated wi

186 associated with the suppression of ROCK2 by high expression of miRNA-139-5p, whereas basal IAS tone

187 vealed a strong positive correlation between high expression of MLK4 and metastatic potential of tumo

188 Taken together, our results show that high expression of MLK4 promotes migratory and invasive

189 Here we report that high expression of monoamine oxidase-A (MAO-A) is associ

190 ver, B cells with Crebbp inactivation showed high expression of Myc and patterns of altered histone a

191 sion patterns, but instead ensures selective high expression of myelin and lipid biosynthesis genes a

192 High expression of NEK2 was predictive of low survival r

193 that centers around the dorsal midline with high expression of neural crest genes, pluripotency fact

194 We conclude that high expression of OAS1 in cancer cells promotes their a

195 High expression of oligomerization-deficient arrestin-1

196 High expression of one of these genes, Fgf13, is associa

197 equirement for vernalization is conferred by high expression of orthologs of the FLOWERING LOCUS C (F

198 Here, we demonstrated that HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1 (HOS1)

199 Here, we identify HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 15 (HOS1

200 psies of human hepatocellular carcinoma show high expression of p38gamma, suggesting that p38gamma co

201 ibodies may be loss of the HER2 receptor and high expression of p95HER2.

202 habdomyosarcomas that is sufficient to drive high expression of PAX3-FOXO1A there.

203 T conv cells had unusually high expression of PD-1 and the IL-33 receptor ST2.

204 The predominant and high expression of PD-L1 by CD11b(+)F4/80(-)I-A(-) glome

205 ors are a potential option for patients with high expression of PD-L1.

206 Previously we reported that high expression of PDI correlated with poor patient surv

207 To understand the high expression of PeMYB11 in harlequin flowers, we isol

208 gh accumulation of anthocyanins as well as a high expression of Phalaenopsis equestris MYB11 (PeMYB11

209 gement of the B-cell receptor (BCR), such as high expression of phosphorylated extracellular signal-r

210 ive BC, we find a strong association between high expression of PLK1 and a shorter metastases-free su

211 High expression of PLOD2 correlated with decreased overa

212 JMJD3 recruitment, and H3K27ac resulting in high expression of PLZF.

213 nscript with 427-nt 3'UTR is responsible for high expression of PolH in various cisplatin-resistant l

214 PMBL is characterized by high expression of programmed death-1 ligand and variabl

215 Here, we initially observed aberrantly high expression of protein kinase Calpha (PKCalpha) in l

216 maging of prostate cancer lesions because of high expression of PSMA in prostate carcinoma cells and

217 High expression of RAC1 correlates with poor clinical pr

218 Damaged cells displayed high expression of rad51, with the gene induced by multi

219 High expression of replication stress markers was associ

220 I/R-induced high expression of Rho-associated protein kinase 2 (ROCK

221 On the other hand, tumor vessels with high expression of S1PR1 (S1pr1 ECTG) show less branchin

222 Functionally, high expression of SDCBP is positively related to ESCC p

223 Furthermore, a high expression of SFRP1 predicted poor prognosis for am

224 olated from alcoholic hepatitis patients had high expression of SIRT1 and SIRT7 and failed to induce

225 n microvascular density, consistent with the high expression of Slco2a1 in the tumour-associated vasc

226 SHH/GLI1 positive samples demonstrated high expression of Snail and Vimentin with relatively lo

227 In HCC patients, high expression of SNHG6-003 closely correlated with tum

228 The high expression of somatostatin receptors on this neuroe

229 Combined low expression of FSTL1 and high expression of SPP1 predicted a poorer prognosis for

230 further provide evidence that the naturally high expression of Srrt in ESCs offsets deleterious effe

231 We suggest that high expression of SSBP1 during RGC differentiation is c

232 umors characterized by PBG involvement and a high expression of stem/progenitor cell markers.

233 Formation of elemental sulfur (S(0) ) and high expression of sulfide quinone oxidoreductase (SQR)

234 (EVs) released by BeWo cells in vitro showed high expression of syncytin-1, but no plac1 expression,

235 Despite high expression of T-bet, a characteristic of short-live

236 nd NK cells, excessive T-cell activation and high expression of T-cell inhibitory molecules are more

237 two distinct asthma subtypes associated with high expression of T-helper cell type 2 cytokines and la

238 to H3K27me3 at this time point, reinforcing high expression of target genes.

239 Our results showed high expression of TCblR/CD320 in the labyrinth of the p

240 fectively inhibit cell viability in AML with high expression of TET1 (i.e., TET1-high AML), including

241 Human SHH medulloblastomas with high expression of the AHR repressor (AHRR) exhibited a

242 We report that high expression of the autophagy marker cleaved LC3 expr

243 ular trap formation (NETosis) in response to high expression of the bacterial type-3 secretion system

244 KG2C+ NK cells while simultaneously inducing high expression of the checkpoint inhibitory receptors L

245 GC Tfh are identified by high expression of the chemokine receptor CXCR5 and the

246 One aspect of this state is high expression of the chemoreceptor odr-10.

247 ssion of interleukin 1 (IL-1) receptor 1 and high expression of the decoy receptor IL-1 receptor 2 an

248 cell line constitutively expressing GCaMP6s; high expression of the GECI was driven by coupling to a

249 Kp80(+) IL-7Ralpha(-) surface phenotype with high expression of the Helios transcription factor.

250 tumor-infiltrating CD8(+) T cells marked by high expression of the immunosuppressive ATP ecto-nucleo

251 mbers were increased in Amish children, with high expression of the innate genes TNF and TNF-alpha-in

252 g an epithelial morphology, sEOC maintains a high expression of the mesenchymal effector, TWIST-1.

253 ide association in lung tissue revealed that high expression of the monocyte-macrophage chemotactic r

254 High expression of the rate-limiting enzyme of de novo G

255 c stem and precursor cells (HSPCs) caused by high expression of the RNA-binding protein Lin28b.

256 ons, we show that the transition from low to high expression of the sigma(70)-controlled stress respo

257 2 expression levels are required to maintain high expression of the signature cytokine IL-21, the coi

258 86); muIs61 strain) nuclear accumulation and high expression of the SOD-3 gene (a DAF-16-specific tar

259 In human disease, high expression of the three Pim isoforms has been impli

260 rolled SLUG expression system, we found that high expression of the transcription factor SLUG was ind

261 Here, we demonstrated that high expression of the TTCC Cav3.1 isoform is related to

262 euroblastoma is a pediatric solid tumor with high expression of the tumor associated antigen disialog

263 to neoadjuvant chemotherapy (P < 0.001) with high expression of these genes being associated with an

264 altered in human cervical cancer tissues and high expression of this lncRNA was associated with worse

265 IFNG-AS1 was evident in memory T cells, with high expression of this long non-coding RNA (lncRNA) and

266 The spheroid surface exhibits high expression of tight junction proteins, VEGF-depende

267 nohistochemical analyses revealed consistent high expression of TMPRSS13 protein on the cancer cell s

268 hages expressed an activation signature with high expression of Tnf, Il1b, and MHC-II at both the tra

269 , high PRKCI expression also correlates with high expression of TNFalpha and YAP1 and low infiltratio

270 Two complete responders had high expression of total HER2 and p95HER2 in baseline ti

271 High expression of Tpm S283D variant in one transgenic m

272 remained largely inaccessible, and retained high expression of transcription factors such as TCF-1.

273 Ectopic or intrinsic high expression of TRIB2 induces drug resistance by prom

274 ated macrophages (NAMs), which are marked by high expression of triggering receptors expressed on mye

275 High expression of TRIM37 induced transcriptomic changes

276 activation systematically correlates with a high expression of Tspan8 protein in melanoma lesions fr

277 d evidence that low expression of IFNAR2, or high expression of TYK2, are associated with life-threat

278 Here we show that high expression of uc.339 correlates with lower survival

279 lico analysis of publicly available cohorts, high expression of USP11 was significantly associated wi

280 iltrating the meninges were characterized by high expression of vascular endothelial growth factor A

281 following CRLM resection was associated with high expression of VEGFC and Nrp-2.

282 FC, but not VEGFD, a finding consistent with high expression of VEGFC in both platelets and avian thr

283 Moreover, high expression of VIP and VPAC1, advanced tumor stage a

284 ans, mouse periodontitis was associated with high expression of Wnt5a and low expression of sFRP5, al

285 High expression of X-linked negative regulators of p53 i

286 y correlate with an MDSC gene signature, and high expression of YAP or MDSC-related genes predicts de

287 se therapy-resistant states characterized by high expression of ZEB1, including epithelial-mesenchyma

288 algorithm delineated clusters with low- and high- expression of genes related to recurrence of disea

289 disease-free survival rate for patients with high-expression of AR was significantly shorter than for

290 fied patients into two groups and found that high-expression of IL-6R mRNA in tumor tissues was a pos

291 Placental alkaline phosphatase also showed high expression on BeWo EVs, but due to concern for cros

292 High expression or aberrant subcellular distribution of

293 scued by recoded allotopic ATP8 (nATP8) in a high-expression plasmid or in a CEN plasmid in the prese

294 BCB1 is a key driver of chemoresistance, and high expression predicts treatment failure in acute myel

295 ficantly correlated with the presence of two high-expression promoter polymorphisms located in the MI

296 In a xenograft animal model, high expression ratio of MSI1 to TNS3 enhanced GBM tumor

297 precision for detecting gene pairs with both high expression similarities and high prior-knowledge ba

298 A similar high expression was seen in liver biopsies, but expressi

299 ined drug resistance without ever developing high expression, while quasifunctional and dysfunctional

300 PCs) such that there are sagittal stripes of high expression (ZII+) interdigitated with stripes of li