ライフサイエンスコーパス: high level of

1 The models developed show a high level of accuracy, correctly assigning 87.20% of AR

2 Prostatic luminal epithelial cells secrete high levels of acetylated polyamines into the prostatic

3 f aposematic patterns is that they contain a high level of achromatic (luminance) contrast, for examp

4 h in tracheoblasts and this is necessary for high levels of activated (phosphorylated) Chk1.

5 should be monitored closely, and persistent high levels of acute-phase reactants should raise concer

6 t that nonlive vaccines will need to provide high levels of Ag recognition throughout the effector ch

7 d for a consistent flux definition, showed a high level of agreement for global and hemispheric CO(2)

8 These findings demonstrate very high levels of agreement among 4 SARS-CoV-2 IgG assays a

9 53, suggesting that tumor cells may adapt to high levels of Akt3, by inactivating the DNA damage resp

10 More than a year later, both patients had high levels of allelic editing in bone marrow and blood,

11 sphatase (ALP) is an important biomarker, as high levels of ALP in blood can indicate liver disease o

12 Moreover, we show that these high levels of amino acids are sufficient to drive HLC a

13 We demonstrated that bears are exposed to high levels of anthropogenic mortality, and the potentia

14 High levels of antibiotic resistance are consistent with

15 However, the high level of antibody in these patients is such that de

16 High levels of antioxidant metabolites in cells with red

17 that family members of ICU patients may have high levels of anxiety, depression, posttraumatic stress

18 health, the genetic variants associated with high levels of anxiety/tension, and high levels of worry

19 nt manner but this activity was abolished at high levels of AP-1 signalling, suggesting contextual re

20 oligomerization reduces the cytotoxicity of high levels of arrestin-1 monomer.

21 ed sterically demanding catalysts capable of high levels of asymmetric induction.

22 atients with NSAb-mediated diseases contains high levels of autoantigen-specific B cells that are lik

23 igate these cellular stresses by maintaining high levels of autophagy, an intracellular lysosome-depe

24 Despite a high level of awareness of LS (85%) and identical recomm

25 nterocytes actively reuptake BAs and express high levels of BA-sensitive nuclear receptors.

26 However, we observe 100% mortality and high levels of bacteraemia within 24 hours when BALB/c m

27 neumolysin, which is rapidly released due to high levels of bacterial autolysis.

28 High levels of beneficial LC-PUFAs and micro-nutrients w

29 In Parkinson's disease (PD), pathologically high levels of beta activity (12-30 Hz) reflect specific

30 alternatives to live viruses, which require high levels of bio-containment, in serological and viral

31 Recent studies have documented the high levels of biodiversity-across many taxa and biomes-

32 ings are observed in Type 2 Hi asthma, where high levels of both 15LO1-PEBP1 and LC3-II are seen in H

33 iGECI exhibits high levels of brightness and photostability and an incr

34 d Annexin A2 (pANXA2), with high affinity at high levels of calcium.

35 High levels of cancer aneuploidy are frequently associat

36 In a country with a high level of care, artesunate was associated with a sho

37 malaria cases in nonendemic countries with a high level of care.

38 These preliminary results showed high levels of catechins (157.18 +/- 34.34 mg/100 g(FW))

39 High levels of CCL2 are associated with increased risk o

40 High levels of Ccr2-chemokines are a feature of regenera

41 s of the anti-inflammatory phenotype express high levels of CD163, a scavenger receptor for the hemog

42 in (the "eat me" signal for macrophages) and high levels of CD47 (the "do not eat me" signal for macr

43 Cells engineered to localize high levels of CDHR2 at filopodial tips acquired interfi

44 High levels of Cdk1 in ESCs phosphorylate and partially

45 knockout mutants for each gene, accumulated high levels of ceramide, indicative of unregulated sphin

46 (e.g., kidney) and blood vessels can express high levels of certain GSLs, not least Gb3Cer/Gb4Cer.

47 t of good practice was made when there was a high level of certainty that the recommendation would do

48 Strains with high levels of CfrA present high levels of glycogen and

49 ted antigen and CCR4 (Ccr4), associated with high levels of chemokine C-C motif ligands 17 and 22.

50 lower adipose tissue mass than animals with high levels of chimerism.

51 diabetes, both of which are characterized by high levels of circulating asprosin.

52 er metastasis in athymic mice accompanied by high levels of circulating GM-CSF and TGFbeta1.

53 ons in promoter sequences contributed to the high level of cis regulation for PAV SPE and non-PAV SPE

54 hin the BRB/BBB are tightly coupled, express high levels of Claudin-5 (CLDN5), a junctional protein t

55 t plantation environment, even in areas with high levels of climatic stress.

56 vaccinate Sprague-Dawley rats, resulting in high levels of cluster of differentiation 8-positive (CD

57 ctors induced by inactivated vaccine require high levels of cognate Ag recognition at the effector ch

58 upposes abstraction capacities and implies a high level of cognitive sophistication.

59 ain and that people generally avoid exerting high levels of cognitive effort.

60 ed, allowing null-hypothesis thresholding at high levels of confidence.

61 tween sister chromatids, Mph1(FANCM) ensures high levels of crossovers and non-crossovers between hom

62 omplete protection, despite the induction of high levels of CSP-specific antibodies.

63 hibit a clear profibrotic signature, express high levels of Cthrc1 (collagen triple helix repeat cont

64 f sequenced E. coli O157:H7 genomes showed a high level of CycA conservation, highlighting a strong s

65 Proinflammatory myeloid cells expressed high levels of CYP27B1 compared with homeostatic myeloid

66 ransferred to this new host, where it showed high levels of cytoplasmic incompatibility, enabling rap

67 ease of neuropeptides requires long-lasting, high levels of cytosolic Ca(2+) However, the molecular r

68 ells in patients with severe disease express high levels of cytotoxic molecules.

69 High levels of DDX21 protein were found in 28% of stage

70 an association between growth inhibition at high levels of defense and dysregulation of Trp biosynth

71 jaz7, jaz9, jaz10, and jaz 13) that exhibits high levels of defense and strong growth inhibition.

72 The high level of degeneracy allows encoding 36 colours with

73 Many primary and metastatic tumors express high levels of DeltaNp63, while DeltaNp63 loss is crucia

74 of life can put children in a trajectory of high levels of dental caries.

75 of 296 000 (range 229 023-420 000) if such a high level of disruption occurred.

76 Because of their high level of diversity and complex evolutionary histori

77 ld be an important mechanism for maintaining high levels of diversity even in environments with few e

78 were assembled and genetic analyses revealed high levels of diversity within the S. indicum group.

79 up to four times more than GAC-PEDS (despite high levels of eDNA loss during desorption).

80 atment-associated toxicity while maintaining high levels of effectiveness.

81 Similarly, DAAM mutants express invariably high levels of Ena in vitro.

82 al radical formed after cyclization provides high levels of enantioselectivity across a variety of su

83 droboration of 1,1-disubtituted alkenes with high levels of enantioselectivity, even when the two sub

84 stereocenters were efficiently prepared with high levels of enantioselectivity.

85 al upwelling zone, revealing an unexpectedly high level of endemism within the Humboldt Current Syste

86 Apart from high levels of energy, proteins, micro- and macronutrien

87 Paradoxically, despite the high levels of Env on the surface of MT-4 cells, 2-fold

88 licating virus versus individuals exposed to high levels of environmental contamination but without v

89 acilitates this adaptation by countering the high levels of environmental stimulation.

90 Patients with TNBC tumors expressing high levels of ERK2 have a poorer prognosis than those w

91 A high level of erythrocyte fetal hemoglobin (HbF) compris

92 y in early-proestrous mice, characterized by high levels of estradiol, whereas memory of mice stresse

93 iff illusion was attenuated among those with high levels of everyday creative experience (study 6) an

94 This high level of expression seems to correlate with poor me

95 In particular, TRP channels showing high levels of expression in sensory neurons such as TRP

96 ods, DIEM better removed droplets containing high levels of extranuclear RNA and led to higher qualit

97 se of e-cigs in indoor environments leads to high levels of fine and ultrafine particles similar to t

98 r neighborhoods to be classified as having a high level of firearm violence.

99 High levels of fluconazole resistance were detected, whi

100 c and molecular regimes that underlie such a high level of foreign gene takeover.

101 ived PfCSP4/38 to immunize mice, it elicited high levels of functional antibodies that had the capaci

102 this strain led to a response that included high levels of gamma interferon (IFN-gamma) and tumor ne

103 revealing several geographic clades but also high levels of gene discordance.

104 growth in Atlantic salmon by exploiting the high level of genetic diversity and trait expression amo

105 plans should concentrate on maintaining this high level of genetic variability through both in and ex

106 These results suggest that high levels of genetic diversity together with the posit

107 Finally, we uncover relatively high levels of genetic diversity, suggesting that Homoth

108 tuted >= 35 distinct genotypes, representing high levels of genetic diversity.

109 breast cancer tumours and is associated with high levels of genomic instability(4-6).

110 in Nicotiana benthamiana This vector yielded high levels of GFP and catalytically active sgRNAs.

111 oconverted microtubules, we demonstrate that high levels of glucose induce rapid microtubule disassem

112 Strains with high levels of CfrA present high levels of glycogen and a decrease in photosynthetic

113 S-overexpressing (IRISOE) TNBC cells secrete high levels of GM-CSF in a hypoxia-inducible factor-1alp

114 A number of studies revealed that high levels of GRP78 protein in cancer cells confer mult

115 on observed by Hadi et al. was resulted from high levels of H-RasV12 overriding anti-cancer mechanism

116 Cities with high levels of heat vulnerability and exposure must be p

117 aBbOhmmDeltaBbSre1 double mutant accumulated high levels of heme and mitochondrial iron, regulating t

118 cells and is coincident with the presence of high levels of heterochromatic H3 lysine nine trimethyla

119 one the major age-related diseases; and 2) a high level of heterogeneity of their phenotype.

120 High levels of heterozygosity present a unique genome as

121 Single copy loss of HIF1A or high levels of HIF2A mRNA expression correlate with alte

122 HIV/SIV latent reservoir, since they harbor high levels of HIV/SIV; reverse CD4(+) T cell immune act

123 In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have be

124 ria (AKU) is a rare disease characterized by high levels of homogentisic acid (HGA); patients suffer

125 nguez et al. show the critical importance of high levels of hypoxia-inducible factor, HIF2alpha/EPAS1

126 Immunological perspective: A high level of IgE cross-reactivity towards allergens fro

127 However, this high level of IL-18BP was not sufficient to neutralize t

128 stimulated macrophages from KI mice secreted high levels of IL-1beta, IL-18, and IL-1alpha but low am

129 High levels of IL-8 in plasma, peripheral blood mononucl

130 n a basal-like molecular subtype and share a high level of immune infiltration and PD-L1 expression,

131 Low IFNgamma response to the SARS-CoV2 and high levels of immunosuppressive IL-10 in both COVID-19

132 gene editing into local parasites conferred high levels of in vitro artemisinin resistance.

133 ecently developed methods that are robust to high levels of incomplete lineage sorting also appear to

134 The region is characterised by high levels of inequities and is also vulnerable to many

135 ition characterized by severe disability and high levels of infected white blood cells.

136 e tumour inflammation, which is reflected by high levels of infiltrating T cells and interferon-gamma

137 ized by an inflammatory signature, including high levels of inflammatory cytokines, alveolar inflamma

138 The animals produced a high level of inhibitory antibodies and were protected f

139 ised to kill cancer cells despite expressing high levels of inhibitory receptors are unknown.

140 The high level of injury to seeds caused by pentatomids is r

141 pected inputs were prominent for moderate to high levels of input similarity.

142 Lymph node metastases, in contrast, display high levels of inter-lesion diversity.

143 , which have aged populations and relatively high levels of intergenerational coresidence, are, all e

144 In the acute phase of MIS-C, we observed high levels of interleukin-1beta (IL-1beta), IL-6, IL-8,

145 er (AUD) involves binge or heavy drinking to high levels of intoxication that leads to compulsive int

146 This demonstrated a high level of intra-colony differentiation, which closel

147 If the current high level of irreproducibility is to be eliminated, it

148 ram that prepares the brain to later execute high levels of juvenile adult sleep.

149 Taken together, high levels of kallistatin exacerbate DN at least partly

150 We show here that high Myosin II activity, high levels of ki-67 and high tumour-initiating abilitie

151 With high levels of knockdown, pn-csERRalpha/gamma knockdown

152 High levels of Kv3.1 and Kv3.3 mRNA and protein were mea

153 deal to examine this topic because they show high levels of leg loss in the field but do not regenera

154 reatment with ivermectin in individuals with high levels of Loa loa microfilariae in the blood preclu

155 AFFF has historically contained high levels of long-chain per- and polyfluoroalkyl subst

156 in 3D culture, has been set at either low or high level of mammographic density (MD) and the organoid

157 t a ZIKV strain from a region of Brazil with high levels of microcephaly (abnormally small head circu

158 routinely collected data, a variable with a high level of missingness or misclassification may deter

159 r degradative systems, chaperone shortage or high levels of mistranslation by ribosomes can result in

160 mosaicism and more than 2 tumors per eye had high levels of mosaicism.

161 nsity had 1.24-fold increased odds of having high levels of mtDNA copy number [Odds ratio (OR) = 1.24

162 This high level of mud supply had sharply declined by the ear

163 Conditioning with CD45-SAP enabled high levels of multilineage engraftment in both Rag1 mut

164 High levels of muscle sensory feedback restrict motor un

165 53 and TGF-beta pathway genes, we identified high levels of MYC expression.

166 Laser printers emit high levels of nanoparticles (PM(0.1)) during operation.

167 strate that the converse is also true, i.e., high levels of ND virus can block the ability of DVGs to

168 als who recover from COVID-19 do not contain high levels of neutralizing activity.

169 Achieving high levels of neutralizing antibodies to the spike prot

170 intranasal dose of ChAd-SARS-CoV-2-S induces high levels of neutralizing antibodies, promotes systemi

171 the E or prM-E proteins and the induction of high levels of neutralizing antibodies.

172 ble HVD and triple HVD/capsid mutants induce high levels of neutralizing antibodies.

173 used to distinguish between the islets with high levels of NF-kappaB transcription factor and contro

174 However, the high level of noise inherent in current scHi-C protocols

175 enomes of mammalian neurons contain uniquely high levels of non-CG DNA methylation that can be bound

176 of DNA methylation, including exceptionally high levels of non-CG methylation.

177 t the phosphorylation of IRT1 in response to high levels of non-iron metals likely triggers dissociat

178 iNKT cells constitutively express high levels of Nr4a1-encoded Nur77, a transcription fact

179 vaccine or two doses of DNA vaccine induced high levels of NS1-specfic antibody and T cell immune re

180 high-in" according to whether they contained high levels of nutrients of concern (i.e., sugars, sodiu

181 Mechanistically, visceral fat maintains a high level of O-GlcNAcylation during fasting.

182 diets is a major contributor to the current high levels of obesity.

183 In some regions with high levels of ocular chlamydia prevalence, additional a

184 ene was expressed in the fae1-1 mutant, with high levels of oleic acid available for elongation, sugg

185 This enabled to obtain an extract with both high level of oleuropein and antioxidant activity.

186 elopmental arrest, interspecies fetuses with high levels of organ chimerism can be generated via blas

187 e associated with extensive riparian canopy, high levels of organic carbon in soils, and suboxic cond

188 ility of a role in cell survival, although a high level of overexpression could be toxic to DA neuron

189 PDACs with high levels of OX40 and low levels of PD-1 were associat

190 However, a high level of oxalic acid, minerals and soluble sugars w

191 Our findings suggest that high levels of pANXA2 in association with elevated calci

192 ion in myeloid cells endogenously expressing high levels of PD-L1.

193 formation, thereby killing cancer cells with high levels of PDE3A and SLFN12 expression.

194 solation and confinement while maintaining a high level of performance with limited support from miss

195 hieving military mission objectives requires high levels of performance from Airmen who operate under

196 phs, and translate text between languages at high levels of performance.

197 dsRNA-analog poly(I:C), PGAM5 oligomers and high levels of PGAM5 were found in mitochondrial aggrega

198 particularly R-EPG and R-EPGO also contained high levels of phenolic compounds (hydroxytyrosol and fl

199 Individually, these traits present medium to high levels of phylogenetic signal, partly related to en

200 leading risk factor for death worldwide, and high levels of physical activity are associated with a l

201 tion of ALD1 resulted in the accumulation of high levels of Pip, which brought about increased levels

202 We previously reported that high levels of plasma neurotensin (NT), a gut hormone re

203 op in a "critical period" (CP), during which high levels of plasticity allow neural circuits to be tu

204 ut also to those traveling to locations with high levels of PM(2.5).

205 ver, this task remains challenging given the high level of polymorphism and homology between HLA gene

206 ukii strain that we sequenced has maintained high levels of polymorphism in some regions of its genom

207 was safe and well tolerated and demonstrated high levels of pre- and post-CHMI protective efficacy.

208 ome and the need for anti-TNF therapy with a high level of precision.

209 pling reactions in the early 2000s brought a high level of predictability and reliability to carbon-c

210 In addition, we show that high levels of preexisting antibody can have a negative

211 We show that high levels of primary and promiscuous functions could h

212 sequently, the activated fibroblasts produce high levels of pro-inflammatory cytokines to promote met

213 associated genes, PTX3+ cells co-expressing high levels of pro-inflammatory markers, APOD+ fibro-adi

214 Microglia produce high levels of progranulin, and reduction of progranulin

215 by expression of FcgammaRIIIA (CD16) and by high levels of proinflammatory cytokine secretion and cy

216 nderstand whether SMC continues to provide a high level of protection and how SMC might be improved.

217 Taken together the results indicate a high level of protection following BBT-059 administratio

218 s rules (precise triage, safe hospital path, high level of protection for health-care teams, prompt d

219 pite strong evidence that SMC is providing a high level of protection, the burden of malaria remains

220 This mutant strain accumulates abnormally high levels of purine nucleotides following amino-acid s

221 TCGA data showed that TNBCs express high levels of RBG regulators, and elevated RRS1 levels

222 rs (12x(PR)) does not form an HLB or express high levels of RD histone mRNA in the presence of the en

223 echnology to prevent drowsy driving suggests high levels of readiness and acceptance for such interve

224 model and clinical hepato-carcinoma samples, high levels of REGgamma in HCC tumor regions contribute

225 e-agent preclinical activity in cancers with high levels of replication stress.

226 iveness to hypoglycemia are observed only at high levels of residual C-peptide that likely contribute

227 n (RR) derived from the F(2) screen showed a high level of resistance to Vip3Aa39 protein, with a res

228 ferent terrain, the moth's policy exhibits a high level of robustness across terrains.

229 an primary AML showed that blasts generating high levels of ROS have increased glucose uptake and cor

230 of this variant to re-associate with NPR1 at high levels of SA remains intact.

231 y, depression, distress, and uncertainty and high levels of satisfaction with testing.

232 w oxidative damage, which is associated with high levels of scavenging systems, possibly resulting fr

233 isk sibships was substantially attenuated by high levels of school attainment and resilience, female

234 High levels of SENP3 in breast cancer are associated wit

235 ts in mice, potent insecticidal effects, and high levels of sequence conservation, we propose that th

236 They showed systemic inflammation with high levels of serum proinflammatory cytokines, inflamma

237 VF-Home can return a high level of short-term compliance and results comparab

238 f the related dengue virus on account of the high level of similarity exhibited by the two viral prot

239 with similar data from rats indicated a very high level of similarity in prefrontal and hippocampal a

240 High levels of skeletal muscle sensory feedback related

241 High levels of SLC43A3 mRNA predicted sensitivity to 6-t

242 ts low solubility, forcing cancer cells with high levels of SLC7A11 (SLC7A11(high)) to constitutively

243 Our data show that high levels of SOB3 expression lead to a short-petiole p

244 In contrast to social cohesion, high levels of social participation at the community lev

245 High levels of soluble CORIN have been reported in PE an

246 is secreted by trophoblastic cells and that high levels of soluble CORIN in preeclampsia have a plac

247 High levels of soluble CORIN were confirmed in maternal

248 s (mAbs) derived from these plasmablasts had high levels of somatic hypermutation (SHM) and recognize

249 Our results revealed broad dissemination and high levels of somatic hypermutation (SHM) of most linea

250 n of the non-neutralizing antibodies display high levels of somatic hypermutation and cross-react wit

251 High levels of SOX11 leads to the expression of markers

252 energy loss spectroscopy, which indicated a high level of sp(2) bonding type consistent with polymer

253 ldren living in neighbourhoods surrounded by high levels of SRI were at a significantly higher risk d

254 ated from gastric cancer stem cells retained high levels of ST6Gal-I and resisted TNF-induced apoptos

255 s can be employed for measurements requiring high levels of stability and resolution with wider impli

256 ted in the cases that involve systems with a high level of structural heterogeneity.

257 The high levels of structural similarity with cyanobacterial

258 We then analyzed regions of the genome with high levels of structural specificity to identify potent

259 Reducing consumption of drinks which contain high levels of sugar and/or alcohol may improve populati

260 miR-1291 agent was selectively processed to high levels of target miR-1291-5p in human pancreatic ca

261 The high level of taxonomic resolution offered by DNA sequen

262 Moreover, the high levels of TGF-beta might be related to the increase

263 )T cells comprise a subpopulation expressing high levels of Th2 and Th17 cytokines, chemokine recepto

264 In addition, the high level of the active ES transcription favors accumul

265 ein solubility and stress resilience through high levels of the ATP-dependent chaperonin TRiC/CCT.

266 Meningeal gammadelta T cells express high levels of the chemokine receptor CXCR6 and seed men

267 which allows for the generation of unusually high levels of the cis-isomer by irradiation with green/

268 adenocarcinoma cells (A549), which expresses high levels of the membrane transporter, using transport

269 ompeted T cells for methionine by expressing high levels of the methionine transporter SLC43A2.

270 were terminally differentiated and expressed high levels of the NKG2C ligand HLA-E.

271 ons are highly frequent in glioma, producing high levels of the oncometabolite D-2-hydroxyglutarate (

272 pecific for a variety of foreign Ags express high levels of the orphan nuclear receptor Nur77, which

273 terial diadenylate cyclase gene and releases high levels of the STING agonist bis-(3'-5')-cyclic dime

274 ronide); MR analysis showed that genetically high levels of these metabolites were associated with lo

275 The pMEI-associated eQTLs and sQTLs show a high level of tissue specificity, and these pMEIs are en

276 Ly6C(hi) monocytes in neonates that express high levels of TLR9 and low levels of TLR7, which may ex

277 In addition, these cells express high levels of TNF-alpha and IL-2, and provide B cell he

278 Fermented avocado puree resulted in high levels of total free amino acids.

279 ion with rhinovirus-16 among asthmatics with high levels of total IgE was compared to the response in

280 ting a physiological adaptation of plants to high levels of toxic metals.

281 e coral snake reveals that organoids express high levels of toxin transcripts.

282 coexert an antitumoral effect by maintaining high levels of transcription of tumor suppressors that p

283 r understand the drivers of these areas with high levels of transmission and help us determine how th

284 d 2%, suggesting the existence of areas with high levels of transmission Overall, 15.6% of heterogene

285 High levels of tumor mesothelin expression were detected

286 Epithelial ovarian carcinoma tissues express high levels of tumor necrosis factor-alpha (TNF-alpha) a

287 ese pDCs were initially capable of producing high levels of type I IFN, but rapidly lost this capacit

288 However, TS cells expressed high levels of type I IFNR subunits (Ifnar1 and Ifnar2)

289 tercountry differences were observed such as high levels of uncertainty and stress in respondents fro

290 nitoring data in space and time can mitigate high levels of uncertainty associated with measurements

291 However, pseudotime estimates are subject to high levels of uncertainty, and failing to account for t

292 e biggest difference for rule creation under high levels of uncertainty, such as when the resource is

293 ntration was the highest in RS patients with high level of urinary oxalate, which was positively corr

294 tion of a major resistance allele conferring high levels of Vip3Aa resistance in a field-derived stra

295 High levels of viral genetic diversity were maintained i

296 ive Epstein-Barr virus (CAEBV) presents with high levels of viral genomes in blood and tissue infiltr

297 n of SARS-CoV-2 in K18-hACE2 mice results in high levels of viral infection in lungs, with spread to

298 etuses but decreased its capacity to produce high levels of virus in the blood of nonpregnant macaque

299 CC fruits had high level of vitamin C (48-108 mg/100 g), malic acid (1

300 ted with high levels of anxiety/tension, and high levels of worry/vulnerability are associated with g