ライフサイエンスコーパス: high molecular weight

1 d Ripr into host membranes as a complex with high molecular weight.

2 suppression in serum is non-steroidal and of high molecular weight.

3 and semiquantitative values for PAHs with a high molecular weight.

4 EC demonstrated that EAE extracted NEPs with high molecular weight.

5 Several IgE-binding proteins of high molecular weight (100- >200 kDa) were detected in p

6 A high molecular weight (148 kDa) PLGA at various concentr

7 Total adiponectin (T-AN) and high molecular weight adiponectin (H-AN) assays were dev

8 itivity (HOMA) and had increased circulating high-molecular weight adiponectin and decreased fasting

9 olubility, a delayed and rapid appearance of high molecular weight aggregates, and an age-dependent t

10 ed a biophysical separation of aging-related high molecular weight aggregates, isolated from the bone

11 are consumed in a time-dependent manner into high molecular weight aggregates.

12 extracts primarily to crystallin peptides in high-molecular weight aggregates and show with MS that t

13 al lobar degeneration (FTLD)-TDP are made of high-molecular-weight aggregates of TDP-43.

14 rently reduced efficiency for the removal of high-molecular-weight alkanes under high-speed/high-load

15 New-generation high-molecular-weight amorphous poly-l-lactic acid scaff

16 aling profile of a novel, sirolimus-eluting, high-molecular-weight, amorphous poly-l-lactic acid-base

17 High molecular weight amyloid beta(1-42) oligomers induc

18 ent in sensor response time when detecting a high molecular weight analyte (streptavidin) versus in t

19 The very high molecular weight and extensive O-glycosylation of g

20 aimed to be a safer alternative due to their high molecular weight and persistence by design.

21 permeability of PROTACs is limited by their high molecular weight and total polar surface area.

22 High-molecular weight and film-forming spiro-ionenes are

23 With its high-molecular weight and hydrophilicity, this conjugate

24 ved sex-specific differences for the sums of high-molecular-weight and di(2-ethylhexyl) metabolites a

25 n fatty amides, gamma- and delta-lactones of high molecular weight, and other aromatic compounds such

26 ained and significant elevation of total and high-molecular weight APN levels and enhanced APN locali

27 High molecular weights are obtained, showcasing the perf

28 olecular hydroarylation reactions to produce high molecular weight aromatic copolymers with 1,1-disub

29 an important role in their association into high molecular weight assemblies, their dynamics, their

30 eus (aSyn-NLS), we found the accumulation of high molecular weight aSyn species altered gene expressi

31 2) atmosphere for subsequent occurrence of a high-molecular-weight atmosphere using a simple model of

32 Our results imply that in order to find high-molecular-weight atmospheres on warm exoplanets orb

33 d with thick H(2)-dominated atmospheres lack high-molecular-weight atmospheres today.

34 eight species usually do not form long-lived high-molecular-weight atmospheres; instead, they are los

35 Despite the known toxicity of some high-molecular-weight azaarenes, their diversity, abunda

36 Deglycosylation treatment attenuated high molecular weight bands, induced a mobility shift, a

37 ion complex-phosphorylated beta-catenin, but high-molecular-weight beta-catenin is unexpectedly incre

38 pears to be irreversible, with both low- and high-molecular weight biologically relevant scavengers f

39 rend in drug development involves the use of high molecular weight, branched, and functionalized poly

40 re also abundant, suggesting a potential for high molecular weight carbon cycling.

41 e inhibition resulted in the accumulation of high molecular weight centromeric transcripts, concomita

42 HF, but not sham-operated mice, demonstrated high molecular weight CgA bands.

43 more aliphatic in nature and contains novel high molecular weight chlorinated DBPs that are detected

44 s were produced in excellent yields and with high molecular weights comparable to those produced usin

45 rk granules in Neoditomiya sp, consists of a high molecular weight complex of luciferin and proteins,

46 y to both NaFl and Evans blue, which forms a high molecular weight complex with serum albumin.

47 This oxidation led to a shift of GRXS17 to a high-molecular-weight complex and thus activated its hol

48 several lines of evidence indicate that the high-molecular-weight complex is the consequence of cova

49 ch in spirochaetes form an unusually stable, high-molecular-weight complex(9,12-17).

50 Blue native PAGE analysis identified high molecular weight complexes containing PAM-1; the ab

51 interactions were detected preferentially in high molecular weight complexes generated by size exclus

52 s with the newly synthesized Cox1 protein in high molecular weight complexes that include the factors

53 Inflammasomes are high molecular weight complexes that sense and react to

54 By promoting the formation of high molecular weight complexes, O-glycans may facilitat

55 components were present in several distinct high molecular weight complexes.

56 have fewer ER stress-induced BiP-containing high molecular weight complexes.

57 CurT is part of several high molecular-weight complexes and Blue Native/SDS-PAGE

58 COX1 mRNA and interacts with Cox1 protein in high-molecular-weight complexes (COA complexes) to form

59 ctive Lyn is sequestered by HSP90-70 to form high-molecular-weight complexes that stabilize and prote

60 Our data revealed that MF6p/FhHDM-1 forms high-molecular-weight complexes when associated with hem

61 y (TROSY)-based NMR optimized for studies of high-molecular-weight complexes, we evaluate whether the

62 nd on the presence of Ulk1 in Lyn-containing high-molecular-weight complexes.

63 a network of stable, survival-facilitating, high-molecular-weight complexes.

64 ed that all ORF45 protein in cells exists in high-molecular-weight complexes.

65 Increased relative fractions of high molecular weight components reduced the oxidation r

66 Polysaccharides are the major high-molecular weight components of wines.

67 ular weight compounds, while the transfer of high molecular weight compounds (>1569 Da) to purees ran

68 ent deployment is especially evident for the high molecular weight compounds such as benzo(a)pyrene.

69 monly applied as means to restrict access of high molecular weight compounds such as proteins.

70 s successfully been used for the analysis of high molecular weight compounds, such as proteins and nu

71 e extracts was linked to the accumulation of high molecular weight compounds, which were matched with

72 (Me)(CH3CN)(+) complexes 4a,b/B(C6F5)3 yield high molecular weight copolymers exhibiting highly branc

73 (Me) with rac-8DL(R) (R=Et, Bu) have yielded high-molecular-weight, crystalline isotactic PHA copolym

74 ences electron transport via an Hmc complex (high-molecular-weight cytochrome c encoded by dvu0531-dv

75 ined with a triple-antibody cocktail against high-molecular weight cytokeratin (HMWCK), p63, and alph

76 Inflammasomes are high-molecular-weight cytosolic complexes that mediate t

77 e reaction conditions for the preparation of high-molecular-weight, defect-free conjugated polymers.

78 studies revealed that immune sera raised to high-molecular-weight Delta123 was poly specific, given

79 hodology that allows for the construction of high molecular weight deoxynucleotide polymers.

80 By intravenous injection of fluorescent high-molecular weight dextran, we confirmed leakage of t

81 The flow instabilities of solutions of high molecular weight DNA in the entangled semi-dilute c

82 One selects specific 0.1-0.2 Mb high molecular weight DNA targets with custom-designed C

83 a single library from approximately 1 ng of high molecular weight DNA, using the 10x Genomics microf

84 Starting from ~1 ng of high molecular weight DNA, we produce barcoded short-rea

85 or the extraction of microgram quantities of high-molecular-weight DNA from human stool samples that

86 eobases, respectively, enabling the study of high-molecular-weight DNA molecules using TROSY approach

87 cal nanoparticles are uniformly dispersed in high molecular weight entangled polymers.

88 in, the actomyosin system and for insoluble, high molecular weight enzyme-protein assemblies in biops

89 enyl ether monomer and its use to synthesize high molecular weight estradiol-polyketal conjugates by

90 ntent, total dietary fiber and proportion of high molecular weight fiber fraction.

91 er, due to their extended aromatic cores and high molecular weight, film formation of large nanograph

92 the cardiovascular system and binds only the high-molecular-weight form of adiponectin.

93 This is due to accumulation of a novel high-molecular-weight form of phosphorylated beta-cateni

94 ulting in the accumulation of sumoylated and high molecular weight forms of retinoid receptors that l

95 We show that high-molecular-weight forms of Delta123 elicit distinct

96 Speciation of organic P in the high molecular weight fraction (>10 kDa) was markedly di

97 detergent-specific abundance of proteins in high molecular weight fractions did not correlate with t

98 otein complexes as indicated by migration in high molecular weight fractions in size exclusion chroma

99 s shown to derive from elevated quenching in high molecular weight fractions, rather than increased (

100 Our results support further investigation of high molecular weight free PEG as a potential method to

101 d protein and all categories of gliadins and high molecular weight glutenins.

102 CshA binds the high-molecular-weight glycoprotein fibronectin (Fn) via

103 the intracellular [Ca(2+)] ([Ca(2+)](i)) and high-molecular-weight glycoprotein secretion.

104 not RvD1, counterregulated the LTB4-induced high-molecular-weight glycoprotein secretion.

105 r observed in poly(vinylidene fluoride) with high molecular weight > 534 kg mol(-1), without the need

106 ion of proteins, high-fidelity MS imaging of high molecular weight (>30 kDa) proteins, and the rapid

107 Cheese whey culture media provided high molecular weight (>3000 kDa) HA products.

108 Under these circumstances, high molecular weight (>669 kDa) (208)Pb and (56)Fe elut

109 The hot water extract consisted mainly of high-molecular weight -> 2,6)-alpha-Man-(1 -> and -> 6)-

110 ong pools of various molecular weights (HMW: high molecular weight, >670-40 kDa; MMW: medium molecula

111 nker flexibility resulted in accumulation of high-molecular-weight H oligomers.

112 Fragmentation of homeostatic high molecular weight HA promoted HPASMC proliferation i

113 eases sensitivity to mechanical stimulation, high molecular weight HA reduces sensitization, attenuat

114 High-molecular weight HA (HMW-HA) is an important compon

115 to degree-of-polymerization 20, leaving the high molecular weight half of the LMWH preparation unass

116 Previous work has suggested that high-molecular-weight (high-MW) DON exists only in two c

117 om a microalbuminuria patient contained both high molecular weight (HMW) (11%) and middle molecular w

118 performance of sIgE detection test for most high molecular weight (HMW) allergens with a pooled sens

119 of Abeta in aqueous extracts of AD brain are high molecular weight (HMW) and relatively inactive.

120 An endogenous high molecular weight (HMW) complex (~5 MD) containing b

121 lmitoylated, N-Ras that is associated with a high molecular weight (HMW) complex.

122 oma cell lines that DJ-1 predominantly forms high molecular weight (HMW) complexes that included RNA

123 xtend megabases along the human genome using high molecular weight (HMW) DNA.

124 60, 120min, and dialysed into low (LMW) and high molecular weight (HMW) fractions.

125 f humans who died with confirmed AD elute at high molecular weight (HMW) on nondenaturing size-exclus

126 ly mainly occurred through the conversion of high molecular weight (HMW) physiological alpha-syn conf

127 ive OAg had a larger molecular size [80 kDa, high molecular weight (HMW)], and in a mouse model of tu

128 inding peptide (P15-1), via interacting with high molecular weight (HMW)HA can enhance the anti-infla

129 ration in LCPM but most importantly also the high molecular weight (HMW, 4-6 ring) PAHs that are cons

130 ifts in response to the same pool of complex high molecular weight (HMW-OM).

131 or exocyst-depleted endothelial cells lacked high-molecular weight (HMW) forms of VWF, demonstrating

132 idues were discovered and characterized from high-molecular weight (HMW) fractions of an IgG1 monoclo

133 or elution of low-molecular weight (LMW) and high-molecular weight (HMW) fractions.

134 Low-molecular-weight (LMW) and high-molecular-weight (HMW) agents have been recognized

135 xpressed in human cells exists in hypoactive high-molecular-weight (HMW) complexes, which can be acti

136 hat a cell culture-derived, disulfide-linked high-molecular-weight (HMW) form of the E2 receptor-bind

137 analytical tools to characterize acidic and high-molecular-weight (hMW) glycopeptides are still lack

138 A high-molecular-weight (HMW) isoform (110 kDa) that conta

139 e hypothesized that assessment of defects in high-molecular-weight (HMW) multimers of von Willebrand

140 e lens, is usually caused by the presence of high-molecular-weight (HMW) protein aggregates or disrup

141 High-molecular-weight (HMW) proteins and low-molecular-w

142 Analysis of the high-molecular-weight (HMW) root exudates of both wheat

143 au relates to the recently described soluble high-molecular-weight (HMW) species that is found in the

144 Activated platelets released high-molecular-weight (HMW)-EGF, produced by a single cl

145 lyzed using HESI contained a large number of high molecular weight homologues containing sulfur and n

146 g subsequent MS2 identification of important high-molecular weight human heart proteoforms such as la

147 signaling in the antihyperalgesia induced by high molecular weight hyaluronan (HMWH).

148 ession and deposition in the interstitium of high-molecular-weight hyaluronan (HA) is principally res

149 saminoglycans (GAGs) chondroitin sulfate and high-molecular-weight hyaluronan (HMW-HA) associated wit

150 We evaluated the mechanism by which high-molecular-weight hyaluronan (HMWH) attenuates nocic

151 iceptor sensitization.SIGNIFICANCE STATEMENT High-molecular-weight-hyaluronan (HMWH) is used to treat

152 Proteomic analyses revealed a decrease in high molecular weight isoforms of the major storage glob

153 e iron overload, and BMSCs implantation with high-molecular-weight keratin hydrogel was selected as t

154 finity (KD </= 0.8 nM) binding site for both high molecular weight kininogen (HK) and factor XII (FXI

155 d levels of plasma kallikrein, which cleaves high molecular weight kininogen (HK) to release bradykin

156 a kallikrein, in the presence and absence of high molecular weight kininogen (HK), an important cofac

157 bserve reduced plasma prekallikrein, cleaved high molecular weight kininogen and elevated plasma brad

158 When the prekallikrein-high molecular weight kininogen complex is bound to endo

159 bility due to the release of bradykinin from high molecular weight kininogen.

160 Plasma concentrations of cleaved high-molecular-weight kininogen (cHK), vascular endothel

161 serine protease known to induce cleavage of high-molecular-weight kininogen (HK) at sites of inflamm

162 ingle-chain precursor form, PK-R371A cleaves high-molecular-weight kininogen (HK) to release bradykin

163 Cleavage of high-molecular-weight kininogen (HK), a marker for activ

164 diverse proteins, including the known ligand high-molecular-weight kininogen (HK), as well as the ext

165 Kallikrein cleaves high-molecular-weight kininogen (HK), releasing the vaso

166 XII (FXII), prekallikrein (PK), and cofactor high-molecular-weight kininogen (HK).

167 vious studies have demonstrated that cleaved high-molecular-weight kininogen (HKa) induces endothelia

168 C1 inhibitor deficiency reduced cleavage of high-molecular-weight kininogen and attacks of angioedem

169 ecombinant FXII-W268R spontaneously triggers high-molecular-weight kininogen cleavage.

170 dose of 300 mg or 400 mg reduced cleavage of high-molecular-weight kininogen in plasma from patients

171 d by measurement of plasma levels of cleaved high-molecular-weight kininogen, and efficacy was assess

172 radykinin release resulting from cleavage of high-molecular-weight kininogen.

173 ofactor activity was ascribed to domain 5 of high-molecular-weight kininogen.

174 n initiated a biochemical fractionation of a high-molecular-weight leptin complex from human plasma a

175 thout affecting their ability to synthesized high-molecular-weight levans.

176 ses multimetallic active sites, and produces high-molecular-weight linear polyethylene.

177 rs were prepared and separated into low- and high-molecular-weight (LMW and HMW) fractions by Sephade

178 ex LH-20 column chromatography into low- and high-molecular-weight (LMW/HMW) fractions.

179 High-molecular weight low-GTPase activity oligomers in t

180 ica serovar Typhimurium is attributed to the high-molecular-weight LPS, we hypothesized that the O-Ag

181 e, we demonstrate that specific silencing of high-molecular-weight MAP2 in vivo abolished induction o

182 pinocytosis, defined by incorporation of the high molecular weight marker tetramethylrhodamine (TMR)-

183 yrrole comonomer to afford a highly soluble, high molecular weight material.

184 ier natural isotopic species, especially for high molecular weight metabolites ( approximately 20% un

185 High molecular weight metabolites were more abundant in

186 rizable" gamma-butyrolactone (gamma-BL) to a high-molecular-weight metal-free recyclable polyester is

187 with high monomer conversions (up to 90 %), high molecular weights (Mn up to 26.7 kg mol(-1) ), and

188 Moreover, high-molecular weight (molecular weight of >450 Da) prod

189 molecular function and impact of MCUB on the high-molecular-weight mtCU complex.

190 LysRS is normally sequestered in a high-molecular-weight multi-aminoacyl-tRNA synthetase co

191 zation of the entire impurity profile of the high molecular weight multifunctionalized PEG-maleimide

192 Hagfish Vwf formed high-molecular-weight multimers in hagfish plasma and in

193 by this symptom, possibly due to the loss of high-molecular-weight multimers of von Willebrand factor

194 Loss of high-molecular-weight multimers of VWF.

195 The biosynthesis of VWF high-molecular-weight multimers requires spatial separat

196 contained protein aggregates in addition to high molecular weight muscle proteins, while the second

197 tested using two different ratios of low and high molecular weight (MW) alginate polymers (75/25 and

198 Many researchers have focused on high molecular weight (Mw) exopolysaccharides (EPS) as a

199 We previously showed that infusion of high molecular weight (MW) free PEG can safely and effec

200 However, top-down MS analysis of high molecular weight (MW) proteins remains challenging

201 on process by shifting Akita proinsulin from high-molecular weight (MW) complexes toward smaller olig

202 prepare polysulfates and polysulfonates with high molecular weight, narrow polydispersity and excelle

203 Beer wort beta-glucans are high-molecular-weight non-starch polysaccharides of that

204 uscle hypertrophy increased the transport of high molecular weight nuclear proteins, while atrophy re

205 odiscs of 10-nm diameter were limited by the high molecular weight of these particles, which caused u

206 effects of HSA on Abeta monomers and soluble high-molecular weight oligomeric protofibrils.

207 id, and glyoxylic acid, but the formation of high molecular weight oligomers is not observed.

208 formation of low molecular weight oligomers, high molecular weight oligomers, protofibrils, and fibri

209 sease-relevant peptide Abeta (1-42) displays high-molecular-weight oligomers even in the absence of s

210 In particular, we relate the presence of high-molecular-weight oligomers of Abeta (1-40) (as foun

211 The dimers assemble into high-molecular-weight oligomers with an apparent two-fol

212 hange of both monomer and dimer species with high-molecular-weight oligomers.

213 s that self-assemble: trimers, hexamers, and high-molecular-weight oligomers.

214 roteorhodopsins with the remineralization of high molecular weight organic matter.

215 to screen the presence of five highly toxic, high-molecular weight PAHs (HMW-PAHs) in coal-tar sample

216 ereotaxic brain injection of human Alzheimer high-molecular-weight paired helical filaments (PHFs) in

217 was to evaluate the chemical degradation of high molecular weight PAM, including the effects of shal

218 High-molecular-weight PBA and diblock copolymers were sy

219 The results allow characterization of high molecular weight PBPs as enzymes and not merely the

220 These proteins are classified by mass into high-molecular-weight PBPs, which are transpeptidases th

221 essable elastomers from Lewis base-decorated high molecular weight PDMS in combination with Lewis aci

222 The concentrations of low- and high-molecular weight phthalate metabolites (SigmaLMWP <

223 tton than polyester and similar for BFRs and high molecular weight phthalates.

224 The MDA5/LGP2 agonist high molecular weight poly I:C improved the antitumor ef

225 n close to the narrow opening is filled with high molecular weight poly-l-lysine.

226 The synthesis of high-molecular-weight poly(vinyl ethers) under mild cond

227 anism for CCL3, CCL4, and CCL5 assembly into high-molecular-weight, polydisperse oligomers.

228 l property by coating PPTA fibers with ultra-high molecular weight polyethylene (UHMWPE) embedded wit

229 observed, leading to lightly branched ultra-high molecular weight polyethylene with M(n) values up t

230 ox-active moieties may be used to synthesize high molecular weight polyethylene with tailored microst

231 talyst for the polymerization of ethylene to high-molecular weight polyethylene hexanes suspension at

232 ermed here as PEO+) which primarily contains high-molecular-weight polyethylene oxide (HMW PEO).

233 The catalyst afforded high molecular weight polyethylenes with narrow dispersi

234 However, facile synthesis of high molecular weight polyketals is challenging, and sho

235 omyosin cycle reactions in the presence of a high-molecular-weight polymer, Ficoll70.

236 ic framework (MOF, UiO-66) and two different high molecular weight polymers (PEO and PVDF).

237 s for the efficient synthesis of families of high molecular weight polymers in one step from readily

238 f parameters were obtained that best produce high molecular weight polymers using this chemistry.

239 ing polymers reacted with diamines to afford high-molecular-weight polymers with triazole- and urea-t

240 tivation are rare, especially for generating high-molecular-weight polymers.

241 Active miRNAs bind target mRNAs in high molecular weight polysome complexes, while inhibite

242 induced the accumulation of proteasome-bound high molecular weight polyubiquitin conjugates and an ap

243 electrically tunable focus made of non-ionic high-molecular-weight polyvinyl chloride (PVC) gel.

244 ed two major macromolecular populations; the high molecular weight population showed a clear trend of

245 empts to synthesize unsubstituted, pristine, high-molecular-weight PPP have failed.

246 llected particles indicates the formation of high molecular weight products.

247 n increased accumulation of disulfide-linked high molecular weight proinsulin complexes and islet vul

248 ltered oxidation of free thiols to form more high molecular weight protein complex(es) than SS, a pot

249 the formation of cross-linked oligomers and high molecular weight protein complexes (HMWC) that are

250 Inflammasomes are high molecular weight protein complexes that assemble in

251 infected human erythrocyte contains numerous high molecular weight protein complexes, which may poten

252 that both of these proteins are contained in high molecular weight protein complexes.

253 m all patients but not controls recognized a high molecular weight protein in renal tubular protein e

254 ed by size exclusion chromatography, and one high molecular weight protein was detected relative to t

255 The aberrant accumulation of insoluble high-molecular-weight protein complexes containing the H

256 est, has facilitated quantitative studies of high-molecular-weight protein complexes.

257 Dop, PafA presents a distinct preference for high-molecular-weight protein substrates.

258 correlate with the urinary concentrations of high molecular weight proteins and correlated only weakl

259 sed by physical and enzymatic degradation of high molecular-weight proteins in shell and epidermis an

260 Animal and vegetable high-molecular-weight proteins present in aerosolized fo

261 mparable with the irreversible adsorption of high-molecular-weight proteins to surfaces, mediated by

262 in large noncrystalline assemblies formed by high-molecular-weight proteins, using modern solid state

263 ntages of greater peak sensitivity, even for high-molecular-weight proteins.

264 an heart proteome and allowed observation of high-molecular weight proteoforms.

265 d the limited degree of Dop interaction with high-molecular-weight pupylated proteins results in pref

266 nceling each other's activity, to generate a high-molecular-weight pupylome.

267 a protein of approximately 80-200 kDa in the high molecular weight region.

268 is used in stoichiometric amounts and has a high molecular weight, resulting in a large amount of ma

269 , we provide the first characterization of a high molecular weight ribonucleoprotein apparatus partic

270 r natural rubber (NR) production, due to its high molecular weight rubber, short breeding cycle, and

271 ysteine-string domain cause CSPalpha to form high molecular weight SDS-resistant aggregates, which ar

272 is under reducing conditions showed that the high molecular weight SE-HPLC peak (peak 1) of the cooke

273 y conditions (RH = 3%) the reaction produces high-molecular-weight secondary ozonides (SOZ), which ar

274 ospheres similar to those of Earth and Venus-high-molecular-weight (secondary) atmospheres-on rocky e

275 on (TcEP) for the template-free synthesis of high-molecular-weight, single-stranded DNA (ssDNA) and d

276 Some have very high molecular weight, some demonstrate in vivo instabil

277 ination and environmental behaviors of novel high molecular weight SPAs, toxicity effects of coexposu

278 ion of a mutant huntingtin protein-dependent high molecular weight species associated with pathogenes

279 ursive cycle, and the development of complex high molecular weight species is explored using a new me

280 nuclein from the rat brain exists as several high molecular weight species of approximately 56 kDa (a

281 ns, and coincides with the detection of both high molecular weight species of Rnq1 and large visible

282 nd McrC subunits oligomerise together into a high molecular weight species.

283 CD3 (aCD3) arm, aCD3 homodimer (aCD3 HD) and high-molecular-weight species (HMWS) are product-related

284 During early magma ocean crystallization, high-molecular-weight species usually do not form long-l

285 ceeds with quantitative conversions allowing high molecular weight star and dendritic block copolymer

286 's activity into the formation of amorphous, high molecular-weight structures that may contribute to

287 Moreover, in the absence of ICP0, high-molecular-weight SUMO-conjugated proteins do not ac

288 Trehalose polyphleates (TPP) are high-molecular-weight, surface-exposed glycolipids prese

289 tau through the formation of nonfilamentous high-molecular-weight tau aggregates, in the absence of

290 au in mice provoked the formation of soluble high-molecular-weight tau, the failure of axonal transpo

291 oung APP/PS1-rTg4510 mice and an increase in high-molecular-weight tau.

292 that is consistent with the accumulation of high molecular weight TDP-43 species and ubiquitinated p

293 High molecular weight, thus sufficient chain entanglemen

294 , loss of TAX1BP1 results in accumulation of high molecular weight ubiquitin conjugates and premature

295 death, but co-immunoprecipitates with fewer high-molecular-weight ubiquitinated peptide species, sug

296 hibition of DUBs resulted in accumulation of high molecular weight ubiquitylated proteins.

297 tive to proteasome inhibition and accumulate high-molecular weight, ubiquitylated proteins that are p

298 ined with over 99 % tail-to-head content and high molecular weight (up to 92.5 kg mol(-1) ).

299 nificantly increased OAg size [220 kDa, very high molecular weight (VHMW)] by expressing in F. tulare

300 AD support caused significant degradation of high-molecular-weight vWF multimers (-9+/-1%, P<0.0001)