ライフサイエンスコーパス: highly structured

1 n give rise to communities that are socially highly structured.

2 possibility that this fusion peptide may be highly structured.

3 o MM-1 in a specific manner without becoming highly structured.

4 cells in these dimensions was nonuniform and highly structured.

5 for the mRNA target even in a region that is highly structured.

6 Animal behavior is highly structured.

7 d visual neuropils of the praying mantis are highly structured.

8 Ecosystems are highly structured.

9 urvive in an environment that is diverse yet highly structured.

10 This implies that the G-matrix will be highly structured.

11 ndary and tertiary structure contacts in the highly structured 16S rRNA.

12 RNAs with highly structured 3' ends, including snRNAs and histone

13 In mammalian selenoprotein mRNAs, the highly structured 3' UTR contains selenocysteine inserti

14 Mechanistically, transcripts with highly structured 3' UTRs are preferentially degraded by

15 increased steady-state levels of mRNAs with highly structured 3' UTRs as well as highly structured c

16 by converting a DNA superlattice first into highly-structured 3D silica scaffold, to turn it from a

17 is-acting RNA elements mainly located in the highly structured 5' and 3' untranslated regions.

18 Enteroviral RNA genomes share a long, highly structured 5' untranslated region (5' UTR) contai

19 All enteroviral RNA genomes have a long and highly structured 5' untranslated region (5' UTR) contai

20 ely 10% of the CVB3 RNA genome consists of a highly structured 5' untranslated region (5' UTR) that i

21 ntron removal and the presence of a long and highly structured 5' untranslated region that inhibits e

22 enger RNA selectivity is proposed to reflect highly structured 5' untranslated regions that depend st

23 d for the translation of mRNAs with long and highly structured 5' untranslated regions, including tho

24 nomes occurs via internal ribosomal entry at highly structured 5' untranslated regions.

25 Central to the flavivirus life cycle are highly structured 5'- and 3'-untranslated regions (UTRs)

26 f a group of mRNAs that possesses a long and highly structured 5'-untranslated region (UTR) containin

27 that translation of MS, which has a long and highly structured 5'-untranslated region, is initiated f

28 lting in repressed translation of mRNAs with highly structured 5'-untranslated regions.

29 ith stimulation of translation of mRNAs with highly structured 5'-untranslated regions.

30 bl mRNA was discovered to possess a long and highly structured 5'-UTR containing a 12-pyrimidine TOP

31 These mRNAs possess highly structured 5'-UTRs that impede ribosome recruitme

32 erved preferential translation of mRNAs with highly structured 5'-UTRs that usually encode factors in

33 cruitment of these initiation factors to the highly structured 5'UTRs of fibroblast-growth factor 9 (

34 fficient 48S complex formation on mRNAs with highly structured 5'UTRs, and that this process requires

35 the Deep Impact encounter returned detailed, highly structured, 5- to 35-micrometer spectra of the ej

36 The highly structured (64% GC) covalently closed circular (C

37 linary rehabilitation team, but incorporates highly structured activity-based therapies, pharmacology

38 Resident among the highly structured adult nervous system, a few cells, ref

39 y process is highlighted by the inability of highly structured alpha-globins to undergo ordered oligo

40 lded microtubule-associated protein Tau to a highly structured amyloid fibril underlies human Tauopat

41 compassing most of the central beta-sheet is highly structured and alpha-helix 3, which is partially

42 point for folding under native conditions is highly structured and already poised to adopt the native

43 ork, constructs a DNA sequence and generates highly structured and annotated sequence representations

44 ctions to transform the nucleus and assemble highly structured and compartmentalized viral genome dom

45 some entry sites (IRESes) of viral mRNAs are highly structured and comprise several hundred nucleotid

46 on function AF-1 and DNA binding domains, is highly structured and contributes significantly to the o

47 esults indicate that DB340 binds to RRE in a highly structured and cooperative complex at a 2:1 DB340

48 ons of neurons whose electrical activity was highly structured and correlated with the images on the

49 (BBM) of intestinal epithelial cells forms a highly structured and dynamic environmental interface th

50 rocircuits in which synaptic connectivity is highly structured and excitatory neurons form subnetwork

51 o TNPO3 architecture and indicate that it is highly structured and exists in a monomer-dimer equilibr

52 dation is surprising, since SsrA RNA is both highly structured and highly abundant.

53 pe 4.3.1), the global S. Typhi population is highly structured and includes dozens of subclades that

54 -untranslated region that is predicted to be highly structured and is important for regulating the ra

55 Four different, both highly structured and nonstructured downstream GC-rich s

56 loop portion of the 690 hairpin folds into a highly structured and novel conformation.

57 calize PrP(C) expression in a tissue that is highly structured and of crucial behavioral importance t

58 by the Cluster mission that clearly show the highly structured and periodic pattern of these waves.

59 Furthermore, these model organisms are highly structured and require correction for population

60 nd then by organizing protein and DNA into a highly structured and stable nucleoprotein 'synaptic' co

61 IMPC mouse clinics worldwide follow rigorous highly structured and standardized protocols for the exp

62 that dimensions outside of this subspace are highly structured and task dependent, suggesting they to

63 lding and suggests that thiopeptoids will be highly structured and therefore potentially useful as th

64 he untranslated region (UTR) predicted to be highly structured and to encode a small ORF.

65 own by circular dichroism spectroscopy to be highly structured and to exhibit about 25% sequence iden

66 ner radiation belt are organized in regular, highly structured and unexpected 'zebra stripes', even w

67 re, the temporal pattern of EOD intervals is highly structured and varies depending on the behavioral

68 ogenic IR spectra of the cleaved glycans are highly structured and virtually identical to those of st

69 dues 22-421, that is proteolytically stable, highly structured, and able to fully support ERAD in viv

70 However, bacterial populations are highly structured, and sampling is biased towards human

71 ully solvent-exposed and mobile, the core is highly structured, and the C-termini are flexible but re

72 Thus, the second SID, SID2, is highly structured, and this alpha helix (helix 2(58-72))

73 The data also clearly show that highly structured ANME-2/Desulfosarcina consortia are no

74 adopts a hairpin structure with a large, but highly structured, apical and internal loops.

75 application of tumor down-staging requires a highly structured approach using a treatment protocol th

76 , we present evidence demonstrating that the highly structured approximately 160-nucleotide adenovira

77 The journey was enlightening, revealing a highly structured, arcane, but rigorous regulatory appro

78 x interactions, which ultimately mediate the highly structured arrangement of cells on a basement mem

79 t twitches are not produced randomly but are highly structured at multiple timescales.

80 at the site of the ciliary dilation (CD), a highly structured axonemal inclusion of hitherto unknown

81 ' turn of CD4 on this tryptophan "stem" are highly structured beta-hairpins in water.

82 how for the first time that pneumococci form highly structured biofilm communities during colonizatio

83 discuss these points we use microbial mats - highly-structured biofilm communities living under sharp

84 Specifically, animals are born with highly structured brain connectivity, which enables them

85 rconducting quantum circuits, we observe the highly structured branching quantum states that support

86 bout their evolutionary adaptations to these highly structured but heterogeneous environments.

87 GroEL-polypeptide complexes assembled into a highly structured but inactive 85.5-kDa alpha beta dimer

88 These data are often highly structured, but that structure is hidden in a com

89 Additionally, bacterial diversity was highly structured by neighbourhood tree competition, whe

90 which hydrolyzes only one peptide bond in a highly structured calcium-binding domain of desmoglein 1

91 procedures for quantifying small amounts of highly structured cDNAs and their RNA templates.

92 VAI consists of an apical stem-loop, a highly structured central domain, and a terminal stem.

93 ntains three domains: an apical stem-loop, a highly structured central domain, and a terminal stem.

94 The resulting highly structured ceramics could have applications in ar

95 se results suggest that HCR-1 functions in a highly structured chromatin environment requiring a comp

96 As with highly structured 3' UTRs as well as highly structured circular RNAs.

97 The highly structured, cis-encoded RNA elements known as rib

98 At neutral pH, DOBMP forms highly structured, clustered dispersions 500 nm in size.

99 pectedly, highly expressed mRNAs contained a highly structured coding sequence (CDS).

100 In addition, NC destabilizes the highly structured complementary trans-activation respons

101 ectable binding to duplex DNA, RusA formed a highly structured complex with a synthetic Holliday junc

102 customized chaperones, with which they form highly structured complexes.

103 elegans neuromuscular junctions (NMJs) were highly structured, composed of building units forming ba

104 uel cells, its near-surface layer exhibits a highly structured compositional oscillation in the outer

105 which four are proline, giving the peptide a highly structured conformation.

106 The specific, highly structured connectivity rules suggest that these

107 ates potentially functional regions that are highly structured, conserved, and contain low synonymous

108 in residues critical to hormone binding were highly structured, constraining potential allosteric mec

109 ligands and contain iron centers embedded in highly structured coordination sites defined by two bulk

110 ions: an unstructured N terminus (1-6) and a highly structured core (7-23).

111 brate TERs are thought to share a conserved, highly structured core domain that includes the templati

112 e activity in the auditory midbrain displays highly structured correlations that vary with distinct n

113 We show that a highly structured course design, based on daily and week

114 of the subunit ectodomain, which contains a highly structured cysteine-rich repeat region.

115 view about the molecule, with citations, and highly structured data for bioinformatics interrogation,

116 eway Molecule Pages (SGMP) database provides highly structured data on proteins which exist in differ

117 ted, ranging from simple data collections to highly structured databases.

118 Bivalent shells possess two highly structured defects, which are composed of a numbe

119 The highly structured differential cross sections directly r

120 in the NMR spectrum are consistent with the highly structured dimeric native state of the protein.

121 Double emulsions are highly structured dispersion systems that generate doubl

122 Tetrahymena thermophila stem-loop IV shows a highly structured distal stem-loop linked to a conformat

123 The structure of one of the toxins reveals a highly structured, disulfide-rich core and a structurall

124 en insensitivity syndrome are located in the highly structured DNA and ligand binding domains.

125 Here, we show that replication of a highly structured DNA in the presence of a unique set of

126 been ascribed to NS5A that is composed of a highly structured domain 1 (D1), as well as two intrinsi

127 An array of highly structured domains that function as metabolite-re

128 iting Enriched Regions (EERs), indicative of highly structured dsRNA.

129 ting and storing human genomic variations in highly structured, easily accessible databases.

130 The presence of highly structured, easily evoked behavioral systems offe

131 This highly structured element induces valylation of the vira

132 es a protein, Rev, which binds to a complex, highly structured element within viral RNA, the Rev resp

133 e extragenic palindromic (REP) sequences are highly structured elements found downstream of approxima

134 ome the translation-inhibitory effect of the highly structured encapsidation signal and other replica

135 Highly structured environments might offer clues.

136 re, we present a nucleotide-level model of a highly structured equilibrium folding intermediate of th

137 ensemble of the encapsulated beta-hairpin is highly structured even at substantially elevated tempera

138 ysis reveals that the decoy influence map is highly structured even beyond the three classic biases.

139 that activity in macaque auditory cortex is highly structured even in the absence of sensory stimuli

140 The plasma is highly structured-exhibiting sharp breaks, smooth variat

141 rom an intrinsically disordered monomer to a highly structured fiber.

142 rix uncovered by this procedure consisted of highly structured fibers, connected to the nuclear lamin

143 twork relies on dynamic communication across highly structured fibre tracts, enabling coherent face p

144 ts highlight the importance of mimicking the highly structured flavivirus surface when designing subu

145 Highly structured FLN spectra obtained at 4.2 K allowed

146 Double emulsions are highly structured fluids consisting of emulsion drops th

147 Each channel involves a stable, highly structured folding intermediate whose kinetic pro

148 The organ of Corti is highly structured for transmitting vibrations originatin

149 oDB, GUS (Genomics Unified Schema) employs a highly structured format to accommodate the diverse data

150 ) and RNA Abundance Database (RAD)] employ a highly structured format to accommodate the diverse data

151 This repeat expansion is highly structured, forming a periodic array of 5'CUG/3'G

152 These conotoxins fold into small highly structured frameworks, allowing them to potently

153 and XNAzymes and can be retargeted to cleave highly structured full-length (>5 kb) BRAF and KRAS mRNA

154 In contrast, chloroplast haplotypes were highly structured (G(STc) = 0.570) and reveal a disconti

155 f rhinophores, tentacles, and mouth showed a highly structured glomerular organization of 5-HT-IR fib

156 should observe forms of reciprocity even in highly structured group environments in which reciprocit

157 Highly structured group intervention did not outperform

158 They can also produce highly structured, high-quality data that could be exami

159 , which infer that such targets will produce highly structured hot electron transport.

160 rs after inhalation of Mtb, following which, highly structured immune structures called granulomas fo

161 ntaneous activity in cortical populations is highly structured in both space and time, (b) the spatio

162 Sensory signals are highly structured in both space and time.

163 tudies show that long-range correlations are highly structured in spatiotemporal patterns, known as r

164 s compartment, the matrix, is bounded by the highly structured inner membrane, which in turn is bound

165 ates were randomly assigned to view either a highly structured instructional videotape about the cons

166 atitis C virus (HCV) RNA is initiated from a highly structured internal ribosomal entry site (IRES) i

167 that ribosomes can efficiently read through highly structured internal ribosomal entry sites, enhanc

168 op V attenuation determinants lie within the highly structured internal ribosome entry site.

169 tions in low-resource settings have employed highly structured interventions delivered by non-profess

170 and in absence of any task, is astonishingly highly structured into spatiotemporal patterns.

171 These signals need to be integrated through highly structured intracellular networks to ensure coher

172 onds, and cryogenic IR spectroscopy provides highly structured IR fingerprints for unambiguous molecu

173 FMDV IRES is phylogenetically conserved and highly structured; it contains four-way junctions where

174 llic systems is to exploit the intricate and highly structured ligands found in natural metalloprotei

175 xplain how long-range correlations flow from highly structured linguistic levels down to the building

176 , the ability of ceramide to localize within highly structured lipid microdomains (rafts) and activat

177 Pharmacological disruption of highly structured lipid microdomains resulted in abrogat

178 n, and it has been shown to efficiently copy highly structured long RNA molecules in a single pass.

179 This highly structured loop contained between helices two and

180 spatial frequency tuning was organized into highly structured maps that remained consistent across t

181 in nanotechnology to direct the assembly of highly structured materials with specific nanoscale feat

182 Bone is a complex highly structured mechanically active 3D tissue composed

183 bacterial cells and further development into highly structured microcolonies.

184 sition state, the antibody pocket provides a highly structured microenvironment for the reaction in w

185 Plant cells create highly structured microtubule arrays at the cell cortex

186 These natural networks are highly structured, modular, coherent, and nested to some

187 mperatures, the rpoH gene transcript forms a highly structured mRNA containing several three-way junc

188 interaction to modulate translation of their highly structured mRNA.

189 is often due to the increased propensity of highly structured mRNAs to be degraded and/or processed

190 o promote the scanning of the 40S subunit on highly structured mRNAs.

191 The optical spectrum of this NC displayed highly structured multiple absorption peaks.

192 se range of ecosystems are often composed of highly structured multispecies communities.

193 sting of a relatively amorphous matrix and a highly structured network of microfibrils embedded in th

194 retical perspective, oscillations constitute highly structured network states that provide limited in

195 Instead, these are highly structured networks held together by receptor dim

196 Behaviour is governed by activity in highly structured neural circuits.

197 Here we show highly structured neuronal encoding of vowel articulatio

198 These highly structured non-coding RNAs of approximately 117 n

199 ymes are catalytically competent examples of highly structured noncoding RNAs, which are ubiquitous i

200 biology and engineering and emphasizes, (i) highly structured, nongeneric, self-dissimilar internal

201 The 5' end of the viral genome contains a highly structured nontranslated region (5'NTR) which fol

202 Strand transfer in highly structured nucleic acid species from the U3 3' lo

203 completely unable to stimulate annealing of highly structured nucleic acids.

204 uences of histones H3 and H4 extend from the highly structured nucleosome core.

205 assays were completed with unstructured and highly structured oligonucleotide complements.

206 of class A beta-lactamases: enzymes that are highly structured on the ps-ns timescale, with important

207 Despite the highly structured organization of the sensory inputs to

208 Our findings reveal a complex, highly structured organization underlying homolog pairin

209 molecular chaperone, transiently binding to highly structured, partially unfolded intermediates of a

210 of HDX simulations in a three-state system (highly structured, partially unstructured, and fully uns

211 ccessible chromatin (ATAC-seq), we observe a highly structured pattern of DNA fragment lengths and po

212 Highly structured, peptide antagonists of the interactio

213 enomous cone snails (genus Conus) use small, highly structured peptides (conotoxins) for interacting

214 Ph)Pz]Cu}(3) compound exhibits an additional highly structured phosphorescence with a vibronic struct

215 Ps to synthesize new soft materials, such as highly structured polymer meshes, are discussed.

216 stry correction, GWAS remains challenging in highly structured populations, such as S. cerevisiae.

217 f association mapping in barley, even within highly structured populations.

218 ce selectively stimulates the translation of highly structured proliferation and tumor-promoting mRNA

219 pper-zinc superoxide dismutase-1 (SOD1) is a highly structured protein and, a priori, one of the leas

220 ibrillation of this exceptionally stable and highly structured protein under mild, physiologically ac

221 involve somatosensory cortical neurons with highly structured receptive fields: these cortical popul

222 nate is 0.46 A for the backbone atoms in the highly structured region and 0.88 A along the entire bac

223 ments reveal that Hsp90 binds to a specific, highly structured region of Delta131Delta.

224 were more frequent but were restricted to a highly structured region of the reporter.

225 sociate with the telomerase RNA depends on a highly structured region rather than specific sequence e

226 uding a shifty heptanucleotide followed by a highly structured region.

227 While knowledge of highly structured regions is integral for mechanistic in

228 slated region of poliovirus RNA contains two highly structured regions, the cloverleaf (CL) and the i

229 Riboswitches represent a family of highly structured regulatory elements found primarily in

230 ns where Mfd regulates transcription contain highly structured regulatory RNAs.

231 Hepatocytes work in highly structured, repetitive hepatic lobules.

232 Highly structured retinal waves were first observed at E

233 zinc finger structures are needed to unfold highly structured RNA and DNA strand transfer intermedia

234 ecific metal ion interactions in this large, highly structured RNA are poorly understood.

235 Analysis of PTE by SHAPE revealed a highly structured RNA comprising seven stem-loop structu

236 ichroism spectra indicated the presence of a highly structured RNA conformation with a significant am

237 CV) internal ribosome entry site (IRES) is a highly structured RNA element that directs cap-independe

238 For example, fungi harbor highly structured RNA elements that humans lack, such as

239 IMPORTANCE HCV has one of the most highly structured RNA genomes studied to date, and it is

240 Our data show C6orf203 to bind highly structured RNA in vitro and associate with the mi

241 irus encodes virus-associated RNA I (VAI), a highly structured RNA inhibitor that binds PKR but fails

242 class-I translational preQ1 riboswitch as a highly structured RNA model whose conformation and struc

243 ocess Rev oligomerizes in association with a highly structured RNA motif, the Rev response element.

244 Ribozymes are highly structured RNA sequences that can be tailored to

245 lows the detection of m(5)C stoichiometry in highly structured RNA sequences.

246 DAD2 and Staufen1 display higher affinity to highly structured RNA substrates.

247 RNase R readily degrades highly structured RNA, whereas its paralogue, RNase II,

248 binding sites and conformational changes in highly structured RNA.

249 lease that has the unusual ability to digest highly structured RNA.

250 5' hydrolytic exoribonuclease able to digest highly structured RNA.

251 Barr virus (EBV) EBER transcripts are small, highly structured RNAs able to bind to and inhibit activ

252 ins accelerate folding and rearrangements of highly structured RNAs and RNA-protein complexes (RNPs)

253 A-binding motifs (dsRBMs) and interacts with highly structured RNAs as well as the dsRNA-activated pr

254 lding transitions involving large regions of highly structured RNAs can proceed in a concerted fashio

255 SHAPE-directed modeling of these highly structured RNAs gave an overall false negative ra

256 ture formation event and suggest that large, highly structured RNAs may have local regions that are m

257 and have developed conditions for purifying highly structured RNAs on a modified tube-gel apparatus.

258 iRNAs such as mir-17~92 and mir-15b~16-2 and highly structured RNAs such as vault RNAs is RanGTP-inde

259 Many lupus autoantigens contain small, highly structured RNAs, and studies have shown that the

260 bonucleases, RNase R can efficiently degrade highly structured RNAs, but the mechanism by which this

261 inger 1 (N-terminal) being more important on highly structured RNAs.

262 o mediate specific interactions with various highly structured RNAs.

263 of spurious association expected to occur in highly structured samples.

264 , folds into a conformation containing three highly structured segments, consisting of contiguous seq

265 uctures remain ill-defined, other than being highly structured, self-propagating, and often fibrillar

266 We have identified a small, highly structured (shs)RNA that binds human recombinant

267 me of the more fascinating features of these highly structured single stranded RNAs (ssRNAs) with emp

268 e human delta hepatitis agent is a circular, highly structured single-stranded RNA lacking regular ru

269 in rat orbitofrontal cortex (OFC) is instead highly structured: single neuron activity co-varies with

270 s at one locus express surface proteins with highly structured size-variable repeating domains, where

271 xhibit distinct physiological signatures and highly structured spatial distributions with mediolatera

272 At both ages, twitches exhibited highly structured spatiotemporal properties at multiple

273 Highly structured specific psychotherapy was moderately

274 plexes consist of SRP proteins and a single, highly structured SRP RNA.

275 proteins fold via parallel channels through highly structured submillisecond intermediates before ac

276 Heparan sulfate is a highly structured sulfated carbohydrate polymer that is

277 When analyzed within the context of highly structured, surface-associated communities (biofi

278 Biofilms are highly structured, surface-associated communities.

279 Here we describe highly structured symbiosomes within three free-living a

280 Gln3 is concentrated in or associated with a highly structured system in the cytosol, one that is pos

281 These results show how the highly structured T stem-loop region in a pre-tRNA subst

282 The accelerating and highly structured temporal pattern of thalamocortical ne

283 Here we generate complex, highly structured, three-dimensional heart-forming organ

284 data and is not well-suited for signals with highly structured time-frequency representations.

285 n proteins reveals a remarkably dynamic, but highly structured, tip growth apparatus.

286 How the ribosomal 30S subunit assembles on highly structured TIR is not known.

287 tify orientations of the apatite crystals in highly structured tissue matrices such as bone.

288 NC destabilizes the highly structured transactivation response region (TAR)

289 These findings disclose a highly structured transcriptional network that couples m

290 for most positions, indicating a polarized, highly structured TSE for folding of P. aeruginosa apo-a

291 vage sites within a large (4.2-kilobase) and highly structured viral mRNA, the 26 S subgenomic RNA of

292 on the interaction of the Rev protein with a highly structured viral RNA sequence, the Rev-responsive

293 he interleukin-2 promoter as well as certain highly structured viral RNAs.

294 he interaction of PKR with a number of other highly structured viral single-stranded RNAs, which inhi

295 R function can be evaded by transcription of highly structured virus-encoded dsRNA inhibitors that bi

296 MMN impairments were more likely to live in highly structured vs independent settings.

297 r cavities can be filled at equilibrium with highly structured water clusters.

298 These highly structured water molecules line up in a string th

299 er that the trapped intermediate ensemble is highly structured with little exposed hydrophobic surfac

300 solution studies suggest that the domain is highly structured, with the three stems assuming a Y-sha