ライフサイエンスコーパス: hippocampus

1 r interactions between the neocortex and the hippocampus.

2 increases in right middle and left posterior hippocampus.

3 activity of spatially sensitive cells in the hippocampus.

4 y decreased neurogenesis in the demyelinated hippocampus.

5 scriptome profiles of genes in the offspring hippocampus.

6 astrocyte subtypes in adult mouse cortex and hippocampus.

7 the dentate gyrus and CA1 subregions of the hippocampus.

8 xpression profiles of specific exons, in the hippocampus.

9 Th and Bdnf genes in the frontal cortex and hippocampus.

10 profiles in the posterior, but not anterior, hippocampus.

11 Neuronal differentiation is inhibited in the hippocampus.

12 in vivo after mAb injections into the rodent hippocampus.

13 ous theta-nested-gamma activity prominent in hippocampus.

14 mpus, and total N-acetyl aspartate (tNAA) in hippocampus.

15 ds to elevated bilateral connectivity in the hippocampus.

16 ect for rs2535629 and rs3617 on ITIH3 in the hippocampus.

17 s in the medial prefrontal cortex (mPFC) and hippocampus.

18 ge-related regenerative decline in the adult hippocampus.

19 -dependent long-term depression (LTD) in the hippocampus.

20 maintenance of latent information within the hippocampus.

21 region, with the greatest number observed in hippocampus.

22 h as the cortex, striatum, hypothalamus, and hippocampus.

23 involved in learning and memory, such as the hippocampus.

24 perience-dependent synapse remodeling in the hippocampus.

25 showing long-term self-renewal in the adult hippocampus.

26 ate neurons throughout life in the mammalian hippocampus.

27 -old adult-born neurons throughout the adult hippocampus.

28 pocampus and PPC, with earlier AR effects in hippocampus.

29 adult-born neurons reverted to normal in the hippocampus.

30 natomically defined subfields within the rat hippocampus.

31 ependence of remote episodic memories on the hippocampus.

32 y recovery of neurotransmitter levels in the hippocampus.

33 citatory input from the intermediate/ventral hippocampus.

34 ociated with neuroinflammation and AD in the hippocampus.

35 ing SST mRNA in cortex and striatum, but not hippocampus.

36 the brain and leads to cell death within the hippocampus.

37 accelerates pathological tau spread into the hippocampus.

38 esis and increased gliogenesis in the mature hippocampus.

39 of fluorescent puncta in the CA1 area of the hippocampus.

40 ing of afferent information from the ventral hippocampus.

41 events in time, a function dependent on the hippocampus.

42 t there was no significant difference in the hippocampus.

43 e formation and maturation in the developing hippocampus.

44 eural hyperactivity in the CA3 region of the hippocampus.

45 kinetics of proliferating progenitors in the hippocampus.

46 ve memory in both the anterior and posterior hippocampus.

47 of indirect, deep-brain targets, such as the hippocampus?

48 gnificantly lower [(11)C]UCB-J BP(ND) in the hippocampus (~10%, p = 0.008, effect size 1.2) and also

49 n neurotransmitter system was studied in the hippocampus, a brain region that is the principal target

50 The human hippocampus, a brain structure crucial for memory across

51 ssed in the forebrain and is enriched in the hippocampus, a region associated with temporal lobe epil

52 (PH) invigorates exploration while anterior hippocampus (AH) supports the transition to exploitation

53 and neuroimaging studies implicated anterior hippocampus (aHC) and amygdala in approach-avoidance dec

54 region and the dentate gyrus (CA3-DG) of the hippocampus, alongside associated memory impairments.

55 These processes are both known to engage the hippocampus, although whether they share similar mechani

56 for the prediction included the cerebellum, hippocampus, amygdala and insular cortex.

57 portions of the subgenual cingulate cortex, hippocampus, amygdala, and putamen as demonstrating conv

58 in T2DM patients, including the prefrontal, hippocampus, amygdala, insular, cingulate, cerebellum, c

59 s of the CNS, primarily the cerebral cortex, hippocampus, amygdala, suprachiasmatic nuclei, anterior

60 cent research has highlighted a role for the hippocampus and a Posterior Medial cortical network in s

61 right cingulum cingulate, the right cingulum hippocampus and anterior corpus callosum (CC) in aMCI co

62 uce damage in brain regions that include the hippocampus and associated limbic structures.

63 layer of the dentate gyrus (DG-GCL) in human hippocampus and contrast these data to those obtained fr

64 X and Y, respectively), and the role of the hippocampus and dorsolateral prefrontal cortex (dlPFC) i

65 In the rodent hippocampus and entorhinal cortex, evidence accumulated

66 36 mRNA expression were observed in the male hippocampus and female midbrain.

67 ts demonstrate lasting effects of PPS on the hippocampus and highlight the utility of EE during adole

68 n impact on encoding-related activity of the hippocampus and immediately adjacent medial-temporal cor

69 The hippocampus and its extended network contribute to encod

70 The interplay between hippocampus and medial entorhinal cortex (mEC) is of key

71 ypes across sub-regions/layers in the dorsal hippocampus and medial entorhinal cortex of rats during

72 y dysfunctional theta phase coupling between hippocampus and medial prefrontal cortex (mPFC).

73 We examined preparatory coding in the human hippocampus and mPFC, two regions that are important for

74 ess to an astrocytic energy reservoir in the hippocampus and neocortex, compromising long-term potent

75 se memories recruit interactions between the hippocampus and nucleus accumbens (NAc).

76 p-down control over mnemonic activity in the hippocampus and other brain structures, often via inhibi

77 is of neuronal cytoplasmic inclusions in the hippocampus and parahippocampus revealed a disease durat

78 ghts into the cross-regional dynamics in the hippocampus and parietal cortex.

79 patterns, similar to recent observations in hippocampus and parietal cortex.

80 gether, these findings demonstrate that (1a) hippocampus and PFC play complementary roles in the impl

81 as greater FA in white matter areas near the hippocampus and posterior limbs of the internal capsule.

82 ation between item and associative memory in hippocampus and PPC, with earlier AR effects in hippocam

83 s linked to altered connectivity between the hippocampus and right dorsolateral prefrontal cortex (PF

84 esting-state functional connectivity between hippocampus and sgACC, associated with sgACC hyper-activ

85 nsumption caused NBCn1 downregulation in the hippocampus and striatum of mice and humans.

86 exhibited greater functional coupling of the hippocampus and striatum.

87 The hippocampus and surrounding medial-temporal-lobe (MTL) s

88 hted MRI, GMV increased throughout bilateral hippocampus and surrounding tissue in nonresponders, whi

89 Cr and tCho levels in ACC and mIns levels in hippocampus and thalamus, but not with tNAA or glutamate

90 one H3 lysine 9 dimethylation) in the dorsal hippocampus and that SETD6 knockdown interferes with mem

91 ent brain structures, such as the vertebrate hippocampus and the arthropod mushroom bodies, are both

92 e signals are more prevalent in the anterior hippocampus and their frequency does not vary with movem

93 remember our past depends critically on the hippocampus and ventromedial prefrontal cortex (vmPFC),

94 vented cognitive decline, neuron loss in the hippocampus, and attenuated inflammation.

95 the muscle contractions did not activate the hippocampus, and in agreement, no DG activation was obse

96 RNA expression than females in the striatum, hippocampus, and midbrain.

97 DA neurons, pyramidal neurons in the ventral hippocampus, and projection neurons in the basolateral a

98 cingulate cortex (PCC), right amygdala, left hippocampus, and right thalamus were significant using m

99 Neural ensembles in prefrontal cortex, hippocampus, and simulated neural networks simultaneousl

100 (neuron-related metabolites) in ACC, DLPFC, hippocampus, and thalamus.

101 is unknown whether activity increases in the hippocampus, and the core network more broadly, play a c

102 ral representations of sensory events to the hippocampus, and the hippocampus is thought to classify

103 ocampus, tCr in ACC and hippocampus, tCho in hippocampus, and total N-acetyl aspartate (tNAA) in hipp

104 ial prefrontal cortex, basolateral amygdala, hippocampus, anterior cingulate cortex, and ventral tegm

105 Sleep oscillations in the neocortex and hippocampus are critical for the integration of new memo

106 s, we performed electrical recordings in the hippocampus as mice navigated in two distinct virtual en

107 oughout the anterior-posterior length of the hippocampus as neurosurgical subjects performed a virtua

108 In vivo, deletion of all LAR-RPTPs in the hippocampus at birth also did not alter synaptic connect

109 These findings place the human hippocampus at the interface of two major brain systems

110 e particularly effective for influencing the hippocampus because rhythmic neural activity in the thet

111 The hippocampus binds reward information into allocentric co

112 ow persistent microstructural changes in the hippocampus both pre- and post-synaptically.

113 (medial prefrontal cortex) and subcortical (hippocampus) brain regions.

114 also prevented hyperactivity in the ventral hippocampus but did not prevent hyperactivity in the bas

115 synaptic depression (LTD) in area CA1 of the hippocampus, but an effect on spine structural plasticit

116 e basolateral amygdala (BLA), but not dorsal hippocampus (CA1), selectively disrupts memories associa

117 OXTR binding in the hippocampus (CA1, CA2/3, CA4, dentate gyrus, subiculum)

118 ognitive, and motor function (e.g. amygdala, hippocampus, cerebellum).

119 pTau protein level was greater in the hippocampus, cerebellum, and brainstem and APP protein l

120 Brains were dissected into frontal cortex, hippocampus, cerebellum, and brainstem.

121 prefrontal cortex and 5-hydroxytryptamine in hippocampus, compared with their counterparts receiving

122 ng and extinction.SIGNIFICANCE STATEMENT The hippocampus contains place cells that encode an animal's

123 to retrieved locations, indicating that the hippocampus coordinates memory-guided eye movements.

124 r absent or directionally discordant in bulk hippocampus data.

125 In "place learning," associated with the hippocampus, decisions are anchored to an allocentric re

126 ances in different regions and layers of the hippocampus dentate gyrus (DG) in an electric stimulatio

127 RSC neurons show hippocampus-dependent activity reminiscent of place cell

128 encountered, as it transfers within similar hippocampus-dependent learning domains but not to other

129 memory losses at 4 and 8 months, it restored hippocampus-dependent location memory in 12-month-old ra

130 The mechanisms underlying the formation of hippocampus-dependent memories during infancy, and the r

131 he ontogeny and the biological correlates of hippocampus-dependent memories.

132 Sleep plays a key role in processing hippocampus-dependent memories.

133 Epigenetic mechanisms are critical for hippocampus-dependent memory formation.

134 memories that in adults are processed by the hippocampus-dependent memory system, and whether the hip

135 ce exerts in promoting the maturation of the hippocampus-dependent memory system, remain to be unders

136 Following two hippocampus-dependent memory tasks, DSW occurrence rates

137 ed avoidance response naturally resistant to hippocampus-dependent reconsolidation made it susceptibl

138 estrous cycle-dependent manner: MAS impaired hippocampus-dependent spatial memory in early-proestrous

139 -dependent learning domains but not to other hippocampus-dependent types of learning.

140 derived interneurons was preserved in mature hippocampus despite early elimination of AMPARs, which r

141 Both dorsal and ventral hippocampus (dH and vH) project to the NAc, but it remai

142 The dorsal hippocampus (DH) is involved in context-induced reinstat

143 (BLA) modulates the consolidation of dorsal hippocampus (DH)-dependent spatial and dorsolateral stri

144 nt across preclinical and human studies, the hippocampus displays alterations due to prenatal distres

145 oid beta toxicity and pathology in the mouse hippocampus due to increased levels of B2 RNA processing

146 citatory and inhibitory balance in the mouse hippocampus during early postnatal development.

147 ediated knockdown of Setd6 in the rat dorsal hippocampus during memory consolidation.

148 mick et al.) has shown that vmPFC drives the hippocampus during memory retrieval, irrespective of how

149 rk increased activity of the targeted (left) hippocampus during scene encoding and increased subseque

150 that activation of interictal spikes in the hippocampus during sleep and seizures specifically impai

151 We report that LASP1 is expressed in rat hippocampus early in development, and this expression is

152 Trajectory-dependent splitter neurons in the hippocampus encode information about a rodent's prior tr

153 ests that populations of "time cells" in the hippocampus encode temporal information.

154 elopment, anatomy, and physiology with human hippocampus, establishing canines as excellent animal mo

155 The hippocampus exhibits traveling 'theta' waves and interac

156 lutamatergic mossy fiber synapses of the rat hippocampus express previously unrecognized electrical s

157 1), putamen (F(1,59) = 87.20; p < 0.001) and hippocampus (F(1,59) = 14.49; p < 0.001) volumes.

158 r, studies examining multiple regions of the hippocampus fail to find links between behavior and tran

159 genes of the MHC II pathway while seahorses (Hippocampus) featured a highly divergent invariant chain

160 gnificantly downregulated in the GFAP-ARO-KO hippocampus following GCI.

161 Projections to the hippocampus from L2 of LEC arise from fan cells in a sup

162 ttle as 30 mg of skeletal muscle or a single hippocampus from Lafora disease mouse models.

163 ed about the physiology and functions of the hippocampus from studies in freely behaving rats.

164 bic interneurons impacts on mPFC and ventral hippocampus functional connectivity before and after ado

165 Dentate gyrus (DG) of the mammalian hippocampus gives rise to new neurons and astrocytes all

166 This suggests that the posterior hippocampus gradually builds the capacity to support det

167 Importantly, posterior hippocampus granularity during windows of putative memor

168 The hippocampus has a major role in encoding and consolidati

169 In humans, volume increase of the hippocampus has been reported, but accurately measuring

170 ork behavior in brain structures such as the hippocampus has been suggested to be controlled, in part

171 ies and discuss how our understanding of the hippocampus has evolved over the last several decades.

172 In the mammalian brain, the hippocampus has the ability to separately encode differe

173 ntegrity of this network, which includes the hippocampus (HC), is fundamental for maintaining cogniti

174 erved a concurrent spindle power increase in hippocampus (HIPP) and neocortex (NC) time-locked to ind

175 oding mechanisms are known to coexist in the hippocampus, how they are influenced by various environm

176 memories depend on interactions between the hippocampus (HPC) and other memory storage networks.

177 The hippocampus (HPC) has recently emerged as a brain region

178 Prefrontal cortex (PFC), hippocampus (HPC), and spleen were then collected and an

179 analyses probed stress effects on the dorsal hippocampus (HPC), basolateral amygdala (BLA), and somat

180 cluding affective motivational behaviors and hippocampus (HPC)-dependent memory [2-5].

181 the medial prefrontal cortex (mPFC) and the hippocampus (HPC).

182 icantly reduced Abeta42/Abeta40 ratio in the hippocampus, improved basal synaptic efficacy, and signi

183 rietotemporal cortex, entorhinal cortex, and hippocampus in the presence of amyloid pathology.

184 ellular/network level analyses in the CA1 of hippocampus in vivo to determine if neural activity, net

185 in the DG-GCL, 15% were not detected in bulk hippocampus, including 15 schizophrenia risk variants.

186 scriptome-wide association studies from bulk hippocampus, including GRM3 and CACNA1C.

187 edict later remembering and suggest that the hippocampus integrates these features into a coherent ex

188 The hippocampus is a brain region critical for cognitive fun

189 Hippocampus is a brain region where adult neurogenesis o

190 network dynamics.SIGNIFICANCE STATEMENT The hippocampus is a part of the mammalian brain that is cru

191 The functional organization of the hippocampus is distributed as a gradient along its longi

192 ve waking, the extracellular activity of the hippocampus is dominated by sharp wave-ripple events (SW

193 The hippocampus is essential for normal memory but does not

194 The hippocampus is implicated in associative memory and spat

195 pus-dependent memory system, and whether the hippocampus is involved in learning and memory processes

196 The hippocampus is likely to play pivotal role in generating

197 f sensory events to the hippocampus, and the hippocampus is thought to classify and sharpen the disti

198 The hippocampus is thought to support memory and decisions b

199 Patients with hippocampus lesions suffer profound failures in episodic

200 In AUD hippocampus, ligand-death receptor pairs, i.e., TL1A-DR3

201 rgic currents onto principal cells in rodent hippocampus likely through a postsynaptic mechanism, and

202 wing loss of NFIA are most pronounced in the hippocampus, manifested by impaired interactions with ne

203 ocation of ECT-related plasticity within the hippocampus may differ according to antidepressant outco

204 n, adult male KO mice showed reduced ventral hippocampus-mPFC-evoked potentials and an augmented low-

205 In the PET subgroup, brain iron in the hippocampus negatively correlated with episodic memory (

206 In the demyelinated hippocampus, neurogenesis was nearly absent in the denta

207 ibition of PTP1B reduced inflammation in the hippocampus, neuronal PTP1B ablation did not.

208 ols, after 6 mo in most areas except for the hippocampus, nucleus accumbens, and thalamus.

209 ndscape of basal TSPO gene expression in the hippocampus of adult (12 weeks old) C57BL6/N mice, follo

210 Gadd45) gamma is selectively impaired in the hippocampus of aged mice with cognitive deficits.

211 ral expression of TrkB 1-486 fragment in the hippocampus of APP/PS1 mice facilitates amyloid patholog

212 impairs the expression of Gadd45gamma in the hippocampus of cognitively impaired male mice.

213 tial mapping of potassium ion release in the hippocampus of freely moving mice.

214 ng produces unique biological changes in the hippocampus of infant rats and mice compared to juvenile

215 lly, we find that overexpressing LSD1 in the hippocampus of tauopathy mice, even after pathology has

216 proinflammatory mediators in the cortex and hippocampus of WT mice, whereas levels were mitigated in

217 d explains the effects of lesions to DLS and hippocampus on these tasks.

218 nders showed increased GMV in right anterior hippocampus only.

219 poral, parietal and frontal lobes, and right hippocampus (p < 0.025 after family-wise error correctio

220 tivity of inhibitory interneurons in the CA1 hippocampus (P = 0.04) which failed to occur in Orai1 KO

221 The top identified regions included the hippocampus, parahippocampus, thalamus, and fusiform.

222 we implemented a computational model of the hippocampus, performing the same task as the human parti

223 Here we report that human posterior hippocampus (PH) invigorates exploration while anterior

224 These findings highlight the hippocampus playing a multifaceted role in socially adap

225 These findings highlight the hippocampus playing a multifaceted role in socially adap

226 es a distributed neural circuit in which the hippocampus plays a central role.

227 The hippocampus plays a critical role in sleep-related memor

228 suggests that, as with awake cognition, the hippocampus plays a significant role in sleep physiology

229 The hippocampus plays an essential role in learning.

230 The more that the hippocampus predicted the category of an upcoming item,

231 Canine hippocampus presents many similarities in fetal developm

232 This region, comprised of the dentate gyrus, hippocampus proper, subiculum, presubiculum, parasubicul

233 cerebellar Crus I; and (3) increased dorsal hippocampus prostaglandins in males only.

234 nucleus accumbens, r = 0.24), memory (i.e., hippocampus, r = 0.32), and sensorimotor processes (i.e.

235 We show that patterned output from the hippocampus reaches both major cell types of deep entorh

236 ovement in recording is most dramatic in the hippocampus region, where the control group showed sever

237 tive microglia in the cerebellum, cortex and hippocampus relative to germ-free mice.

238 from the medial temporal lobe, including the hippocampus, reveal the existence of two classes of cell

239 RNA-sequencing of the hippocampus revealed that stress increased several canon

240 choices elicited a suppression signal in the hippocampus, revealing sensitivity for the subjective pe

241 leep was associated with bilateral volume of hippocampus (right: p = 0.001; left: p < 0.001), thalamu

242 arby gene expression (rs2714700/MAGI2-AS3 in hippocampus; rs1862416/TENM2 in lung), and expression of

243 reveal electrophysiological patterns in the hippocampus selectively involved in associative memory e

244 Among the prominent inputs to PL, the hippocampus shares with PL a role in both working memory

245 ised by extensive neuronal loss in different hippocampus sub-regions.

246 ation of projections from the macaque monkey hippocampus, subiculum, presubiculum, and parasubiculum

247 we introduce a computational model in which hippocampus subserves place and MB learning by learning

248 In the hippocampus, subunits alpha1, alpha2, alpha5, beta2, bet

249 The hippocampus supports episodic memory via interaction wit

250 The hippocampus supports memory for facts and events, collec

251 rved for mIns in hippocampus, tCr in ACC and hippocampus, tCho in hippocampus, and total N-acetyl asp

252 n the middle group were observed for mIns in hippocampus, tCr in ACC and hippocampus, tCho in hippoca

253 e networks, functional connectivity within a hippocampus-thalamus-striatum network decreased only in

254 ual behaviour and increased responses in the hippocampus than controls.

255 et spiking activity was much stronger in the hippocampus than in three other brain regions (amygdala,

256 and synaptic and cellular alterations to the hippocampus that last into adulthood.

257 however the molecular mechanisms within the hippocampus that underlie contextual extinction behavior

258 are spatially modulated neurons found in the hippocampus that underlie spatial memory and navigation:

259 famous-novel pairs becomes separated in the hippocampus, that is, more distinct from one another thr

260 In hippocampus, there were heterogenous changes in the numb

261 In the hippocampus, Tiam1 is predominantly expressed in the DG

262 s, and later encoding processes that recruit hippocampus to bind these features together.

263 by serial mediation through testosterone to hippocampus to emotion dysregulation.

264 mine the role of expectation in shifting the hippocampus to perform pattern separation.

265 g evidence suggests that the contribution of hippocampus to place learning may also underlie its cont

266 pecifically, we applied LFS in the sclerotic hippocampus to study the effects on spontaneous subclini

267 the propagation of network activity from the hippocampus to the medial entorhinal cortex.

268 ific mass spectrometry analysis of the aging hippocampus, together with an in vitro site-directed mut

269 rates that statistical regularities bias the hippocampus toward representing future states over curre

270 Cells in the hippocampus tuned to spatial location (place cells) typi

271 ranscripts in three complex samples of human hippocampus using deep sequencing.

272 s accumbens (NAc) afferents from the ventral hippocampus (vHIP) are implicated in stress-induced susc

273 -frequency communication between the ventral hippocampus (vHPC) and medial prefrontal cortex (mPFC) i

274 RNA-seq of the ventral hippocampus (vHpc) highlights that E2-dependent gene exp

275 tress (CRS) up-regulated Pdcd4 expression in hippocampus via decreasing mTORC1-mediated proteasomes d

276 ume, which corresponds to 29% of the overall hippocampus volume.

277 ompared with controls was found only for the hippocampus (VR, 1.14; p = 0.036; CVR, 1.30; p < 0.001),

278 The presence of a mixed supplied hippocampus was an advantage in several cognitive domain

279 neurons confirmed that IL-1 receptor in the hippocampus was critical for stress-induced behavioral d

280 t, and the rate of volume change in the left hippocampus was negatively correlated with the period of

281 Brain imaging revealed that the hippocampus was responsible for this interference betwee

282 reinstatement of oscillatory patterns in the hippocampus was stronger for successful recollection.

283 The extent to which the hippocampus was suppressed was associated with flexibly

284 stigate how these functions are mixed in the hippocampus, we recorded from single hippocampal neurons

285 responsive brain regions interconnected with hippocampus were differentially activated across high an

286 sts and MRI measures of white matter and the hippocampus were evaluated as endpoints.

287 ations of middle temporal gyrus (MT/V5), and hippocampus were found in the aesthetic judgments of dyn

288 Other cells in the Wls(fl/-);Gfap-Cre hippocampus were minimally affected, as determined by si

289 e mature nervous system, particularly in the hippocampus, where its functions are largely unknown.

290 ly remembered as old further depended on the hippocampus, where the presence of more distinct represe

291 tion, a cognitive operation performed by the hippocampus wherein existing mnemonic representations ar

292 r cingulate cortex but also in precuneus and hippocampus, which are key regions implicated in structu

293 c memory formation depends critically on the hippocampus, which binds features of an event to its con

294 of autism-related PSD-95 and Homer-1 in the hippocampus, which were missing in the singular MIA or H

295 ded single neurons in the MFC, amygdala, and hippocampus while human subjects switched between making

296 ebral blood flow (CBF) in bilateral anterior hippocampus, while responders showed CBF increases in ri

297 gyrus/CA(2,3) and subiculum subfields of the hippocampus, while simultaneously leading to the formati

298 colitis-induced enhanced infiltration of the hippocampus with macrophages and inflammatory myeloid ce

299 normalizing excessive firing in the ventral hippocampus without affecting anxiety-like behaviors and

300 ocytes of the prefrontal cortex (PFC) or the hippocampus would produce behavioral abnormalities that