ライフサイエンスコーパス: histidine-rich protein

1 r proportion were positive for P. falciparum histidine rich protein 2 (192/246 [78.0%]) vs 811/1154 [

2 We compared the performance of a histidine rich protein 2 (HRP-2)-based RDT (First Respon

3 hrp3 that result in variable performance of histidine rich protein 2 (HRP2)-based rapid diagnostic t

4 st African country to discontinue the use of histidine rich protein 2 (HRP2)-detecting rapid diagnost

5 diagnostic tests (RDTs) detect P. falciparum histidine rich protein 2 (PfHRP2) and cross react with P

6 Plasmodium falciparum with the histidine rich protein 2 gene (pfhrp2) deleted from its

7 Rapid diagnostic tests (RDTs) detecting histidine-rich protein 2 (HRP2) and HRP3 are widely used

8 We compared RDTs based on histidine-rich protein 2 (HRP2) and RDTs based on Plasmo

9 imarily detect Plasmodium falciparum antigen histidine-rich protein 2 (HRP2) and the malaria-conserve

10 lood spots (DBS) which were later tested for histidine-rich protein 2 (HRP2) antigen (n = 8029).

11 a rapid diagnostic tests (mRDTs) that target histidine-rich protein 2 (HRP2) are important tools for

12 erase chain reaction (qPCR) and detection of histidine-rich protein 2 (HRP2) in plasma by enzyme-link

13 Histidine-rich protein 2 (HRP2) is produced by Plasmodiu

14 ecificity of the diagnosis, and the level of histidine-rich protein 2 (HRP2) may reflect the parasite

15 inces in Angola with known concentrations of histidine-rich protein 2 (HRP2), aldolase, and lactate d

16 um aldolase and lactate dehydrogenase (LDH), histidine-rich protein 2 (HRP2), P. vivax LDH (PvLDH).

17 ged between 6 months and 6 years using rapid histidine-rich protein 2 (HRP2)-based diagnostic tests (

18 control and elimination, and Haiti relies on histidine-rich protein 2 (HRP2)-based rapid diagnostic t

19 etect Plasmodium falciparum via its abundant histidine-rich protein 2 (HRP2).

20 Plasmodium falciparum parasites lacking histidine-rich protein 2 (pfhrp2) and 3 (pfhrp3) genes e

21 ic tests (RDTs) detect Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and PfHRP3, but deleti

22 at detect the Plasmodium falciparum-specific histidine-rich protein 2 (PfHRP2) antigen are the primar

23 pability using malaria Plasmodium falciparum histidine-rich protein 2 (PfHRP2) antigen detection.

24 tate dehydrogenase (pLDH), and P. falciparum histidine-rich protein 2 (PfHRP2) antigens.

25 th the malaria antigen Plasmodium falciparum histidine-rich protein 2 (PfHRP2) as an example of targe

26 uency of Plasmodium falciparum isolates with histidine-rich protein 2 (pfhrp2) gene deletion as one o

27 , and to investigate potential P. falciparum histidine-rich protein 2 (pfhrp2) gene deletions.

28 Plasma concentrations of P. falciparum Histidine-Rich Protein 2 (PfHRP2) have diagnostic and pr

29 bodies specific to the Plasmodium falciparum histidine-rich protein 2 (PfHRP2) malaria antigen.

30 However, the GM P. falciparum histidine-rich protein 2 (PfHRP2) values (95% CI) increa

31 was carried out using Plasmodium falciparum histidine-rich protein 2 (PfHRP2), a malaria parasite bi

32 apid quantification of Plasmodium falciparum histidine-rich protein 2 (PfHRP2), a malaria parasite bi

33 sor was used to detect Plasmodium falciparum histidine-rich protein 2 (PfHRP2), an important malaria

34 ing antibodies against Plasmodium falciparum histidine-rich protein 2 (PfHRP2).

35 The most prevalent P. falciparum RDTs detect histidine-rich protein 2 (PfHRP2).

36 asma concentrations of Plasmodium falciparum histidine-rich protein 2 (PfHRP2).

37 nd the plasma concentration of P. falciparum histidine-rich protein 2 (PfHRP2).

38 emonstrated in the presence of P. falciparum histidine-rich protein 2 (PfHRP2); however, the molecula

39 utility of plasma concentrations of parasite histidine-rich protein 2 (pHRP2), a Plasmodium-specific

40 d with age, independent of parasite biomass (histidine-rich protein 2 [HRP2]).

41 Plasmodium falciparum parasites lacking histidine-rich protein 2 and 3 (pfhrp2/3) genes have bee

42 diagnostic testing with a multiple-antigen (histidine-rich protein 2 and pan-lactate dehydrogenase p

43 of which detect circulating parasite-derived histidine-rich protein 2 antigen (PfHRP2) in capillary b

44 a (i) the detection of Plasmodium falciparum histidine-rich protein 2 antigen and (ii) multiplexed an

45 ests (RDTs) for falciparum malaria recognize histidine-rich protein 2 antigen.

46 nge in the presence of Plasmodium falciparum histidine-rich protein 2 at a concentration well below c

47 e presence of Plasmodium falciparum-specific histidine-rich protein 2 by using an antigen-capture imm

48 biomass estimated from plasma P. falciparum histidine-rich protein 2 correlated positively with dise

49 malaria parasites lacking the P. falciparum histidine-rich protein 2 gene (pfhrp2) have been observe

50 v) a malarial antigen (Plasmodium falciparum histidine-rich protein 2) for clinical research.

51 a concentrations of a malaria protein, HRP2 (histidine-rich protein 2) would serve this purpose.

52 the antibody directed against P. falciparum histidine-rich protein 2, which was used in the ParaSigh

53 sethylamodiaquine (MDAQ) was measured with a histidine-rich protein 2-based enzyme-linked immunosorbe

54 erformance of Plasmodium falciparum-specific histidine-rich protein 2-based rapid diagnostic tests (R

55 , we investigated the diagnostic accuracy of histidine-rich protein 2-based RDTs using qualitative po

56 next-generation sequencing, we estimate that histidine-rich protein 2-based RDTs would miss 9.7% (95%

57 be 4.5 pM in serum for Plasmodium falciparum histidine-rich protein 2.

58 ng rapid diagnostic tests (RDTs) that detect histidine-rich protein 2.

59 for Plasmodium falciparum malaria target the Histidine-Rich Proteins 2 and 3 (HRP2 and HRP3).

60 n diagnostic-resistant parasites mediated by histidine-rich proteins 2 and 3 (pfhrp2/3) deletions tha

61 relies on detection of Plasmodium falciparum histidine-rich proteins 2/3 (HRP2/3) through rapid diagn

62 eneration of VLR monoclonal antibody against histidine rich protein-2 (HRP-2) of Plasmodium falciparu

63 . falciparum (Pf)-LDH, P. vivax (Pv)-LDH, Pf-histidine-rich protein-2 (HRP2), and C-reactive protein.

64 Plasma Plasmodium falciparum histidine-rich protein-2 (PfHRP-2) concentrations, a mea

65 parasitemia and plasma Plasmodium falciparum histidine-rich protein-2 (PfHRP2).

66 nsitive nanobiosensor detection platform for Histidine-rich protein-2 having a limit of detection of

67 s of endothelial and platelet activation and histidine-rich protein-2 levels, but remained associated

68 in, ADMA, symmetric-dimethylarginine (SDMA), histidine-rich protein-2, and angiopoietin-2 were measur

69 dy, we assessed the accuracy of a dual-band (histidine-rich protein-2/pan-lactate dehydrogenase [HRP2

70 s routinely used in these diagnostic kits is Histidine-rich protein-2; a protein synthesized and rele

71 KAHRP (the knob-associated histidine-rich protein), a member of this group, has bee

72 A recombinant domain of knob-associated histidine-rich protein, a major protein found in both me

73 The histidine-rich proteins appear to compete with the Ni-de

74 Microscopy, a histidine-rich protein-based RDT, and two different real

75 otein HSPB5 (alphaB-crystallin), a Cys-free, histidine-rich protein chaperone that responds to cellul

76 Knob and knob-associated histidine-rich protein expression, CD36 adhesion, and an

77 sandwich ELISA for the detection of malarial histidine-rich protein from Plasmodium falciparum (Pf HR

78 Rapid diagnostic tests based on detection of histidine-rich proteins (HRPs) are widely used for malar

79 Two of these proteins, the histidine-rich proteins I and II (PfHRPI and PfHRPII), a

80 The histidine-rich protein II (HRP II) from Plasmodium falci

81 The histidine-rich protein II (HRP II) from Plasmodium falci

82 Antibodies identified histidine-rich protein II (HRP II) in purified digestive

83 Histidine-rich protein II (HRPII) is an abundant protein

84 Histidine-rich protein II (HRPII) is secreted by Plasmod

85 A candidate heme polymerase, the histidine-rich protein II (HRPII), is proposed to be del

86 gnostic tests based on Plasmodium falciparum histidine-rich protein II (PfHRP-II) and P. falciparum l

87 the malarial biomarker Plasmodium falciparum histidine-rich protein II (pfHRPII) from a complex matri

88 stic protein biomarker Plasmodium falciparum histidine-rich protein II (pfHRPII) from human plasma an

89 the malarial biomarker Plasmodium falciparum histidine-rich protein II (PfHRPII).

90 Ethiopia had the lowest PPVs (histidine-rich protein II [HRP2] assay, 17.35%; parasite

91 lciparum (MoabPf and PoabPf) for recombinant Histidine rich protein-II antigen (Ag) of Pf (rHRP-II Ag

92 o antigens diagnostic of recent infection Pf histidine-rich protein-II (HRP-II) and 6NANP, Pf-vaccine

93 laria RDT that targets Plasmodium falciparum histidine-rich protein-II (HRPII) and Plasmodium lactate

94 om transposon Tn 5, were expressed under the histidine-rich protein III (HRPIII) gene promoter and te

95 ng the genes encoding native knob-associated histidine-rich protein (kahrp) and erythrocyte binding a

96 n fails to bind the parasite knob-associated histidine-rich protein (KAHRP), an essential cytoadheren

97 nds on the parasite-derived, knob-associated histidine-rich protein (KAHRP).

98 parasite)/protein4.1(host) and P. falciparum histidine rich protein (PfHRP1) (parasite)/protein4.1(ho

99 Particularly interesting new cysteine- histidine- rich protein (PINCH) is an adaptor protein th

100 (the particularly interesting cysteine- and histidine-rich protein) plays a pivotal role in the asse

101 H. pylori can utilize stored Ni via defined histidine-rich proteins to aid colonization of the host.

102 The gene encodes a histidine-rich protein, which we refer to as "hZIP4," wh