ライフサイエンスコーパス: histologic

1 MR, the findings were similar: Molecular and histologic activity and DSA were not important compared

2 n, we evaluated urinary CD163 agreement with histologic activity in 19 patients from the Mexican coho

3 ng/mmol perfectly agreed (kappa=1.0) with a histologic activity index <=1 or >1 in repeated biopsies

4 clinical severity, histologic class, and the histologic activity index.

5 nd multivariate analysis were conducted with histologic anal high-grade squamous intraepithelial lesi

6 g of intestinal peristalsis in zebrafish and histologic analyses of intestinal tissues from patients

7 Histologic analyses of lesions were completed.

8 Micro-computed tomography and histologic analyses showed that berberine treatment sign

9 cantly promoted, as seen in the micro-CT and histologic analyses.

10 value (PPV) of (18)F-DCFPyL PET/CT based on histologic analysis and to compare with pelvic multipara

11 Histologic analysis of pulmonary vessels in patients wit

12 Histologic analysis of small intestine tissues from IDO1

13 Macroscopic and histologic analysis revealed a reduced soft tissue wound

14 ty evaluation by in vivo microtomography and histologic analysis were performed.

15 patients with mucosal healing (based on the histologic analysis) using serum samples from patients w

16 The results of histologic analysis, as well as intact parathyroid hormo

17 oholic fatty liver disease (NAFLD), based on histologic analysis, compared with no alcohol consumptio

18 By histologic analysis, cone lipofuscin was found in outer

19 Serum and livers were harvested for histologic analysis, fatty acid profiling, and measureme

20 Furthermore, histologic analysis, immunohistochemistry, RNAscope in s

21 bserved in MS lesions and was conformed with histologic analysis.

22 indings from whole-exome, transcriptome, and histologic analysis.

23 Liver damage was characterized by histologic analysis.

24 We performed histologic and biochemical analyses of intestinal tissue

25 Liver biopsies were analyzed to define histologic and biochemical features associated with the

26 Here we show transcriptomic, histologic and cellular profiles of post mortem COVID-19

27 Histologic and chemical measures of fibrosis revealed in

28 We assessed the validity of a combined histologic and endoscopic (Mayo endoscopy subscore, 0 or

29 In addition to histologic and endoscopic assessment, esophageal biopsy

30 monoclonal antibody against IL13) to reduce histologic and endoscopic features compared with placebo

31 ween specific gastric molecular profiles and histologic and endoscopic features, providing insight an

32 a range of upper gastrointestinal symptoms, histologic and endoscopic findings.

33 We examined subclinical histologic and functional changes in kidney transplant r

34 Widespread reports of histologic and gene expression changes consistent with a

35 genesis of organized, vascularized bone with histologic and mechanical characteristics comparable to

36 fungoides and Sezary syndrome and maintained histologic and molecular characteristics of their clinic

37 Rigorous digitally measured histologic and molecular markers suitable for gluten cha

38 om a prospective study of 1679 biopsies with histologic and molecular testing, we selected one random

39 We assessed the associations between histologic and noninvasive tests (NITs) for fibrosis wit

40 Histologic and transcriptomic analyses revealed that Sfr

41 We used histologic and ultrastructural analyses, as well as clin

42 e prognostic value of 12 electron microscopy histologic and ultrastructural changes (descriptors) fro

43 We assessed relevant biochemical, histologic, and gene expression markers of kidney injury

44 ported the clinical, functional, radiologic, histologic, and hemodynamic characteristics, response to

45 28-day, micro-computed tomography scanning, histologic, and immunofluorescence staining were conduct

46 tudied the relative association of clinical, histologic, and molecular variables with risk of kidney

47 s to nearly complete resolution of clinical, histologic, and transcriptomic features of psoriasis.

48 m caused extensive improvements in clinical, histologic, and transcriptomic features of psoriasis.

49 e defined by more severe atopic, endoscopic, histologic, and transcriptomic features.

50 cyclophosphamide administration, followed by histologic assays and immunostaining.

51 and cytologic atypia) outperformed standard histologic assessment in an independent validation cohor

52 ce ODC activity in Tsc2-RG mice, followed by histologic assessment of brain development.

53 , and screening for cancer risk focuses upon histologic assessment of dysplasia within endoscopic bio

54 mography, scanning laser ophthalmoscopy, and histologic assessment of retinal morphology, we found th

55 ography imaging, visual function testing and histologic assessment, we observed a reduction in retina

56 Radiographic and histologic assessments for pulp regeneration were perfor

57 haracterized using a range of functional and histologic assessments, including nasal potential differ

58 abase, for which the percentage extent of 11 histologic attributes was available on corresponding his

59 stic radiomic features with disease-specific histologic attributes, with implications for risk-strati

60 yperreflective specks (HRS); we identified a histologic candidate for HRS.

61 individual INPC criteria (age at diagnosis, histologic category, mitosis-karyorrhexis index (MKI), g

62 The independent prognostic ability of age, histologic category, MKI, and grade were validated.

63 Histologic, cellular, microcomputed tomography, and elec

64 Sustained gluten exposure reliably induces histologic changes but is burdensome.

65 h decreased serum creatinine and ameliorated histologic changes compared with WT animals.

66 ly the KI/KO mice have clear skeletal muscle histologic changes in MFM.

67 years after kidney transplantation, chronic histologic changes such as arteriolar hyalinosis and mes

68 (HLA-ID)) to HLA non-ID to investigate which histologic changes were likely due to alloimmune injury

69 transplant glomerulopathy, but most chronic histologic changes were similar to less-well matched LDK

70 We analyzed histologic changes with respect to baseline and longitud

71 Livers from LD and MC mice were subjected to histologic changes, hepatic leukocyte population, hepati

72 to improve noninvasive predictions of tumor histologic characteristics, molecular profile, distincti

73 d correlated with disease clinical severity, histologic class, and the histologic activity index.

74 Aim of the pilot study was the histologic classification of the inflamed peri-implant s

75 n of well-differentiated G3 NENs, the newest histologic classification.

76 ificant correlations between visually scored histologic components and network-based measures.

77 mprove diagnostic value in patients for whom histologic confirmation is not easily obtained.

78 rmance in guiding percutaneous biopsies with histologic confirmation of lung lesions.

79 Here, we explore the biomechanical and histologic consequences of aging in black African-Americ

80 dings underscore the importance of assessing histologic CRC subtypes independently.

81 Histologic criteria for diagnosing acute rejection in va

82 etermined based on clinical, endoscopic, and histologic criteria.

83 sy-proven based on World Health Organization histologic criteria.

84 icroscopy showed the pathogen throughout the histologic cross-sections of burned skin.

85 responding reduction in oxidative stress and histologic damage compared to untreated NMP kidneys.

86 emonstrating improved serum creatinine, less histologic damage, reduced proinflammatory cytokine prod

87 ete imaging data and conclusive cytologic or histologic diagnoses.

88 Images in patients with a histologic diagnosis (n = 227) were used to train and ev

89 +/- 18 [standard deviation]; 250 women) with histologic diagnosis confirmed at biopsy or surgical exc

90 only cases for which a definitive diagnosis (histologic diagnosis or >=1 year stability on imaging te

91 To compare the histologic difference in healing between ridge preservat

92 7), and histologic response (modified global histologic disease activity score of 4 or less).

93 Histologic disease activity was evaluated in 2630 coloni

94 IL-21, activity and resulted in clinical and histologic disease remission in 3 patients and marked im

95 (ROC) and decision curve methodology against histologic EPE as standard of reference.

96 Histologic evaluation is the gold standard for grading a

97 Histologic evaluation of the residual fibril masses reve

98 of 42 patients dying with COVID-19, autopsy histologic evaluation revealed acute tubular injury, whi

99 Gross and histologic evaluations of the capsules were used to asse

100 ll under investigation, preclinical data and histologic evidence demonstrate that biologic-based tech

101 There was histologic evidence of acute herpesvirus pathology, incl

102 contrast material had greater functional and histologic evidence of acute kidney injury than wild-typ

103 active MMP-9 expression by 97%, ameliorated histologic evidence of injury, and reduced ALT by 58%, w

104 that are disrupted in schizophrenia and the histologic evidence suggesting abnormal kappa opioid rec

105 Histologic examination revealed prominent choroiditis wi

106 The presence of PanIN/PDAC as visualized by histologic examination was compared with autoradiography

107 d histologic examination, tumor viability at histologic examination, and vandetanib tissue concentrat

108 amma(-/-) mice were assessed using necropsy, histologic examination, IHC analysis, flow cytometry, an

109 luded bead distribution at x-ray imaging and histologic examination, tumor viability at histologic ex

110 fter IR, WT mice had worse mucosal damage on histologic examination.

111 We provide descriptive OCT and histologic examples of disease progression.

112 orectal tumors have been classified based on histologic factors, genetic factors, and consensus molec

113 We quantified the changes in histologic feature abundance for murine cohorts with onc

114 Our CNNs learned a hierarchy of recognizable histologic feature representations to classify the major

115 The unique histologic features and early presentation of disease in

116 symptom persistence despite normalization of histologic features and symptom resolution after esophag

117 h risk because of diminutive polyps advanced histologic features and their risk for metachronous adva

118 had disease progression to CP, with similar histologic features as those observed in human HP.

119 Improvement in histologic features associated with improved fibrosis fo

120 Replacing INPC with individual histologic features in the COG risk classification will

121 dometrial carcinoma characterized by unusual histologic features including discrete malignant epithel

122 However, overlapping histologic features may cause a diagnostic dilemma.

123 standard and clinicians' diagnosis was when histologic features of ABMR were present but donor-speci

124 resolution after esophageal dilation despite histologic features of active disease.

125 expression of proinflammatory cytokines and histologic features of colitis.

126 ith active EoE, dupilumab reduced dysphagia, histologic features of disease (including eosinophilic i

127 We also assessed histologic features of EoE (peak esophageal intraepithel

128 injections of antioxidants, only NAC reduced histologic features of liver damage and serum levels of

129 regressions to identify associations between histologic features of NAFLD severity and moderate alcoh

130 s are accompanied with chronic inflammation, histologic features of nonalcoholic steatohepatitis, ker

131 led in placebo groups of clinical trials had histologic features of progression within 2 years, in as

132 t knowledge about immunologic, clinical, and histologic features of virus- and drug-induced lesions o

133 r-specific antibody [DSA]) and molecular and histologic features reflecting injury (acute kidney inju

134 ng for rapid and objective quantification of histologic features relying solely on hematoxylin and eo

135 The individual histologic features underlying the INPC have prognostic

136 was identified and validated when individual histologic features were analyzed in lieu of INPC.

137 In 51,510 diminutive polyps, advanced histologic features were observed in 7.1% of polyps from

138 ts with MCAS-T showed unique morphologic and histologic features when compared with controls.

139 tes, positive predictive values, tumor size, histologic features, and receptor profile were compared.

140 polyps), or discarding a polyp with advanced histologic features, could result in a patient being con

141 l multimodal imaging features and associated histologic features.

142 because their diminutive polyps had advanced histologic features; and the risk of these patients for

143 roportion of diminutive polyps with advanced histologic features; the proportion of patients classifi

144 in MRE was associated with increased odds of histologic fibrosis progression (odds ratio [OR], 3.56;

145 iver stiffness on MRE may be associated with histologic fibrosis progression and progression from ear

146 ytic vasculitis was an easy and reproducible histologic finding.

147 3 United States kidneys discarded because of histologic findings could be accurately matched to very

148 sis from the core-needle specimen versus the histologic findings in the surgical specimens when core-

149 breast imaging radiologists blinded to final histologic findings interpreted DBT examinations by usin

150 le volume less than 500 mm(3) (P = .03), and histologic findings of invasive adenocarcinoma (P < .001

151 However, when we considered histologic findings of malignancy and follicular prolife

152 from the initial cohort showed inconclusive histologic findings on revision and were reassigned as s

153 BEST PRACTICE ADVICE 1: Review histologic findings with experienced pathologists who sp

154 inations, 74 mammographic findings had final histologic findings, including 31 masses (26 malignant),

155 benign and 17 (22%) lesions showed malignant histologic findings.

156 to determine the association between PET and histologic findings.

157 iver of lung adenocarcinoma, the most common histologic form of NSCLC.

158 y, alone or in combination with demographic, histologic, genomic, or proteomic data, be used for clin

159 more nodal involvement ( P = .02), and lower histologic grade ( P = .001).

160 Rates of histologic grade 1 invasive cancer were 0.5 per 1000 scr

161 e histopathologic features, including higher histologic grade and anaplasia, and also with both unila

162 The TNBC samples tended to have a higher histologic grade and proliferation index and had higher

163 esophageal locations (P < .0001), validated histologic grade and stage scores (both P < .0001), and

164 Treatment selection is based on histologic grade and underlying pathobiology with low-gr

165 level, digital rectal examination findings, histologic grade group (GG) from transrectal US-guided b

166 However, underestimation of histologic grade may occur because of tumor heterogeneit

167 MRI-targeted biopsy alone underestimated the histologic grade of some tumors.

168 as administered according to tumor location, histologic grade, and extent of resection.

169 idating the multivariate analysis found that histologic grade, intratumoral S100 dendritic cells, and

170 detected in PDAC and correlates with higher histologic grade.

171 f (18)F-FDG PET imaging and compared it with histologic grading.

172 ication of all NEN grades and is superior to histologic grading.

173 The long-term histologic groups differed significantly in biological s

174 deep-learning algorithm can learn objective histologic H&E features that predict the clinical subtyp

175 Nucleolar prominence is a histologic hallmark of CaP; however, the expression, loc

176 Crown-like structures (CLS) are histologic hallmarks of the proinflammatory process in a

177 The prevalence of anal histologic HSIL (hHSIL) was 27% (95% confidence interval

178 ologist-based interpretation of conventional histologic images (overall accuracy, 94.6% versus 93.9%)

179 eural networks (DNNs), complex properties of histologic images can be rigorously and reproducibly qua

180 Moreover, interpretation of intraoperative histologic images is dependent on a contracting, unevenl

181 ofluorescent translation (SHIFT) which takes histologic images of hematoxylin and eosin (H&E)-stained

182 used DNN-based transfer learning to analyze histologic images of periodic acid-Schiff-stained renal

183 lgorithm with the ability to digitally stain histologic images, achieving reliable nuclei segmentatio

184 Histologic imaging of the tibial marrow compartment, alp

185 We used histologic, immunofluorescence, RNA sequencing, and meta

186 We evaluated associations between histologic improvement (defined as the composite of neut

187 tients (24/71, P = .0009) with endoscopic or histologic improvement alone after induction, respective

188 Histologic improvement and endoscopic improvement follow

189 and maintained significantly higher rates of histologic improvement at induction week 8 and maintenan

190 3 induction and maintenance trials, we found histologic improvement in a greater proportion of patien

191 I-PDFF) from baseline may be associated with histologic improvement in nonalcoholic steatohepatitis (

192 Ustekinumab induces and maintains histologic improvement in patients with ulcerative colit

193 Histologic improvement was significantly (P < .0001) ass

194 n placebo when more stringent definitions of histologic improvement were used.

195 Clinical and histologic improvements in patients correlated with part

196 Urinary CD163 reflects histologic inflammation in lupus nephritis and is a prom

197 In addition, histologic inflammation was identified as a risk factor

198 was no evidence of increased inflammation or histologic injury in old grafts.

199 h which cells are harvested according to the histologic layers of mouse colon, and we compared cellul

200 Histologic lesions consisted of epidermal hydropic chang

201 mains unclear, due, in part to the fact that histologic lesions used to characterize early TCMR can b

202 TC was defined as same-nodule histologic malignancy.

203 with electronic microscopy, may be a useful histologic marker for active SARS-CoV-2 infection in kid

204 crease, which correlated with an increase in histologic markers of cell death and preceded decrease i

205 can then be confirmed based on clinical and histologic markers of improvement on the gluten-free die

206 NAFLD and control individuals, we associated histologic markers of NAFLD severity with significant de

207 econdary outcomes included serum markers and histologic measures of fibrosis improvement and NASH res

208 ces in adipose tissue fibrosis compared with histologic measures.

209 mice; livers were collected and analyzed by histologic, metabolomic, messenger RNA quantification, a

210 Functional, histologic, molecular, and pharmacologic assays characte

211 ytes of omics data but also in detailing the histologic-molecular correlations required for looking i

212 fication and delineation of brain regions in histologic mouse brain sections is especially pivotal fo

213 of the patients with borderline NASH in the histologic NAS score, 48% were classified as NASH by SAF

214 (median age 45, 81% women, and 81 [46%] with histologic NASH) were used for model derivation.

215 explore parameters that best correlated with histologic NASH, and MRI-PDFF to estimate steatosis.

216 : After complete eradication (endoscopic and histologic) of intestinal metaplasia has been achieved w

217 t the end of maintenance therapy than either histologic or endoscopic improvement alone.

218 Substantial improvement in histologic outcomes, including fibrosis, is directly cor

219 nfluenza-associated respiratory failure, the histologic pattern in the peripheral lung was diffuse al

220 , and the usual interstitial pneumonia (UIP) histologic pattern.

221 er researchers to apply this tool to measure histologic patterns for clinical and basic science studi

222 training of machine learning classifiers for histologic patterns in whole-slide images.

223 roarray analysis with extensive clinical and histologic phenotyping from 224 kidney transplant recipi

224 In order to investigate the relationship of histologic populations, mate-pair sequencing (MPseq) and

225 Four histologic prognostic groups were identified (< 18 month

226 py had a long-term beneficial effect against histologic progression.

227 Secukinumab improved clinical scores and histologic psoriasis features.

228 areas of freshly resected tissue to provide histologic-quality images of surgical margins without ph

229 R2(TCMR) correlated with histologic rejection although with many discrepancies, a

230 Supervised classifiers trained on histologic rejection showed less agreement with histolog

231 ulation was analyzed in 77 biopsies with "no histologic rejection" (NHR; n = 25), "clinical TCMR" (cT

232 ssion was defined as absence of clinical and histologic relapse and no premature withdrawal for any r

233 V-EoE was more likely to attain histologic remission via dietary restriction (P < .0001)

234 red and four adults with EoE in clinical and histologic remission, from 29 European study sites, were

235 epithelial tissues, leading to clinical and histologic resolution of blisters.

236 ntly greater proportion of patients achieved histologic response (>=50% decrease in GHAS from baselin

237 onance index of activity score below 7), and histologic response (modified global histologic disease

238 early on-treatment factors associated with a histologic response at 72 weeks.

239 liver fat reduction assessed by MRI-PDFF and histologic response in NASH.

240 decline in MRI-PDFF relative to baseline and histologic response in NASH.

241 tween 30% relative reduction in MRI-PDFF and histologic response in obeticholic acid (OCA) versus pla

242 The rate of histologic response in those who achieved less than 30%

243 We identify a unique very early histologic response pattern to anti-PD1 therapy in cHL t

244 f point for relative decline in MRI-PDFF for histologic response was 30% (using Youden's index).

245 Histologic response was defined as a 2-point improvement

246 4.86 (95% CI, 1.4-12.8, P value < 0.009) of histologic response, including significant improvements

247 entify clinical parameters associated with a histologic response.

248 Histologic results from core biopsy specimens determined

249 Collectively, the molecular and histologic results support the hypothesis that Acomys ha

250 assessed by comparing radiologic images with histologic results.

251 tumors, with a significant increase in mean histologic score, than infected Apc(Min/+) mice.

252 treatment, corresponding with improvement in histologic score.

253 eal intraepithelial eosinophil count and EoE histologic scores), endoscopically visualized features (

254 efined by the NASH clinical research network histologic scores.

255 on of 107.1%; P < .0001 vs placebo), the EoE-histologic scoring system (HSS) severity score by 68.3%

256 Using the NAS histologic scoring system bears the risk of underdiagnos

257 The EPX histologic scoring system can be used to differentiate c

258 ic Steatohepatitis Clinical Research Network histologic scoring system.

259 ur study, obtaining deeper and/or additional histologic sections from the other surface of the tissue

260 nalysis of formalin-fixed, paraffin-embedded histologic sections.

261 xia levels reflected in pimonidazole-stained histologic sections.

262 ADH1B*2 and moderate alcohol consumption and histologic severity of NAFLD.

263 Histologic slices were evaluated by immunostaining for c

264 Rationale: Histologic stains have been used as the gold standard to

265 All histologic subgroups, except teratoma, express this mark

266 d epithelial ovarian cancer risk overall, by histologic subtype and by participant characteristics.

267 In addition, each PRCC histologic subtype had its own set of mutational changes

268 Prognosis is good and the histologic subtype is a significant predictor for diseas

269 ly described "macrotrabecular-massive" (MTM) histologic subtype of hepatocellular carcinoma (HCC) (MT

270 The histologic subtype was found to be the main predictor fo

271 rates were estimated by race and ethnicity, histologic subtype, and stage.

272 age, clinical T or N stage, tumor location, histologic subtype, or prior neoadjuvant therapy.

273 PF correlated significantly with tumor site, histologic subtype, relative tumor size, and primary met

274 per 1 SD increase in TFA level and assessed histologic subtype-specific associations with multivaria

275 Two histologic subtypes of squamous cell carcinomas (SCCs) w

276 .696, p = 0.113) were the specific malignant histologic subtypes that demonstrated the greatest benef

277 In Group B (n=45), the most common histologic subtypes were IDC (82.2%) and LA (46.5%); the

278 In Group A (n=53), the most common histologic subtypes were infiltrating ductal carcinoma (

279 However, analysis of histologic subtypes, including adenocarcinoma (the focus

280 gating the metabolic differences between two histologic subtypes, the epithelial-mesenchymal transiti

281 incurable, and can be categorized into three histologic subtypes: epithelioid, biphasic, and sarcomat

282 wall, belonging to one of the following five histologic subtypes: high-grade myxoid liposarcoma (HG-M

283 MT- 27%; P < 0.001) and more likely for histologic TC (70% vs 16%, P < 0.001).

284 analysis of thymocytes and splenocytes, and histologic/transcriptomic analyses of thymic tissue.

285 l chemoimmunotherapy, refractory disease, or histologic transformation (tFL) have limited progression

286 HR-OCT has the potential to predict histologic tumor margins in OSSN.

287 As the principal histologic type of liver cancer, hepatocellular carcinom

288 juvant CTRT for p53abn tumors, regardless of histologic type.

289 e for associations of physical activity with histologic types and lung cancer in ever and never smoke

290 Because histologic types are subjective and difficult to reprodu

291 had medulloblastoma, and 51 (23%) had other histologic types of CNS tumors.

292 ecific cancer sites, stage at diagnosis, and histologic types.

293 Ten TGCTs with 1-3 histologic types/tumour were sequenced.

294 were able to perform CT-guided biopsies with histologic validation of the nonresponding lesions in 7

295 Histologic validation was obtained in 80 locations with

296 ovement in fibrosis to improvements in other histologic variables, resolution of steatohepatitis, and

297 nant Hodgkin lymphoma (NLPHL) is an uncommon histologic variant, and the optimal treatment of stage I

298 cinomas (UCs) by tissue microarray, on which histologic variants and molecular subtypes had previousl

299 cement of areas of glomerular capillaries in histologic variants of FSGS are unknown.

300 markers stratified by molecular subtypes and histologic variants.