ライフサイエンスコーパス: histology

1 ieved during keratoplasty were processed for histology.

2 n treatment decisions for patients with ABMR histology.

3 Further 33 had advanced disease, 30 benign histology.

4 ions or applied to point patterns outside of histology.

5 sis-related keratopathy were concordant with histology.

6 g metastases were quantified and analyzed by histology.

7 ed the lack of improved accuracy from adding histology.

8 nt of the PDL in DMD and its confirmation by histology.

9 o identify stent strut coverage validated by histology.

10 This gradient was confirmed by histology.

11 different regarding their relationship with histology.

12 apid resolution of rejection as confirmed by histology.

13 and remodeling assessments were performed by histology.

14 pletely (<=99%) necrotic based on transplant histology.

15 y measuring albuminuria and examining kidney histology.

16 1 or Day 5) and were routinely processed for histology.

17 restored and tissue damage being observed in histology.

18 ted States are discarded because of abnormal histology.

19 ed 92 patients, of whom 14 (15%) were of ILC histology.

20 surgery generally have improvements in liver histology.

21 echocardiography, morphometric analysis, and histology.

22 measures are when compared to the underlying histology.

23 , respectively, regardless of primary tumour histology.

24 recipient and control mice was confirmed by histology.

25 identify biomarkers to supplement or replace histology.

26 say, and intestinal tissues were analyzed by histology.

27 sed to correlate the fluorescent images with histology.

28 e the limitations of conventional bread-loaf histology.

29 fety of the method were validated by MRI and histology.

30 lations and validated from human GBM patient histology.

31 ith greater dysbiosis but no change in liver histology.

32 children that relate to improvement in liver histology.

33 graphy) that bridges the gap between MRI and histology.

34 flect tissue morphological heterogeneity and histology.

35 d Tumors [RECIST] version 1.1) regardless of histology.

36 ed by backscattering electron microscopy and histology.

37 and an in-depth analysis of subcutaneous AT histology.

38 ed tomography, microcomputed tomography, and histology.

39 in vivo and ex vivo findings, confirmed with histology.

40 Eighteen patients had ND and 7 had MBEN histology.

41 ten different tumour types and 19 different histologies.

42 tly-fused genes within different brain tumor histologies.

43 ne phenotypes that transcend specific tumour histologies.

44 A total of 2235 struts were reviewed by histology, 1216 were considered as well-matched struts w

45 Eleven percent (5/44) of PB displayed normal histology, 13.6% (6/44) fibrosis, 34.1% (15/44) inflamma

46 By histology, 160 struts were identified as uncovered, whil

47 Of 224 biopsy specimens, 56 had ABMR histology; 26 of these (46.4%) lacked detectable serum H

48 nts, predictors of CRM+ included signet-ring histology (38.1% vs. 26.7% non-mucinous, and 26.9% mucin

49 71% of patients were men, 84% had clear cell histology, 53% were at intermediate risk of recurrence,

50 followed-up with serial MRI, PET scans, and histology 6 months post-radiation.

51 st for patients with T1stage and epithelioid histology (69.8 months/54.1%).

52 Examining histology, a doubling of estradiol was associated with a

53 fusion-positive non-small-cell lung cancers; histology-agnostic approvals have yet to be granted.

54 ally, we discuss the challenges intrinsic to histology-agnostic drug development in oncology, includi

55 s been created to facilitate the approval of histology-agnostic indications.

56 rize the development and testing of approved histology-agnostic therapeutic agents and present data o

57 mplexities faced by drug developers pursuing histology-agnostic therapeutic agents.

58 es or Amsterdam II criteria) or endometrioid histology alone would have missed 9/16 (56%), 8/13 (62%)

59 ap and are sometimes indistinguishable using histology alone, were also investigated and the predicti

60 the FGGT, which was also correlated with the histology analyses where a greater number of medium and

61 issue graft was harvested from each side for histology analyses.

62 shortened host survival in many human cancer histologies and in murine cancer models.

63 be consistent with known measurements using histology and adaptive optics and/or OCTA, the selected

64 and GGT are associated with change in liver histology and appear to be powerful indicators of histol

65 melanomas that present inherently ambiguous histology and are challenging to classify.

66 econdary endpoints included changes in liver histology and development of liver-related outcomes.

67 deling and cardiac function were assessed by histology and echocardiography.

68 cer had a lower proportion of adenocarcinoma histology and epidermal growth factor receptor (EGFR) mu

69 Readouts included bladder histology and ex vivo assessments of urothelial prolifer

70 vels in multiple organs at adult age, normal histology and fertility.

71 Histology and flow cytometry on spleens and thymi from 3

72 Cardiac histology and function, BP, sodium and potassium excreti

73 udied differences in epithelial thickness by histology and gene expression by Affymetrix gene arrays

74 pleural (Pl) MM, implicating nonepithelioid histology and high vimentin, AKT1/2, and Galphai2 expres

75 three-dimensional (3D) approach for virtual histology and histopathology based on multi-scale phase

76 The results were confirmed by PET, histology and ICPMS.

77 The gold standards were histology and imaging follow-up.

78 lecular markers that can complement existing histology and imaging methods used to diagnose and class

79 interval, 86.3%-99.7%) by the combination of histology and imaging/clinical follow-up.

80 ere collected from some mice and analyzed by histology and immunofluorescence to quantify mast cells

81 Liver tissues were collected and analyzed by histology and immunofluorescence, and mesenchymal cells

82 ty and collected tumors and analyzed them by histology and immunohistochemistry to assess neural remo

83 Histology and immunohistochemistry were performed in pan

84 other tissues were collected and analyzed by histology and immunohistochemistry.

85 ard for diagnosis of tumors with overlapping histology and immunophenotype, such as small round blue

86 Rather, histology and in vitro experiments indicated 4-AP stabil

87 enerating en face images that correlate with histology and may be used to overcome the limitations of

88 Histology and microcomputed tomography were used to asse

89 ended to increase cementogenesis measured by histology and microcomputed tomography, while Scl-Ab del

90 e highly concordant with both WHO integrated histology and mutation classification as well as methyla

91 currently classified through integration of histology and mutation information, with new development

92 d assessment of muscle mechanics, innovative histology and oxygen tension modelling, we have comprehe

93 ues were collected from mice and analyzed by histology and real-time PCR; enterocytes were isolated b

94 Liver biopsy samples were analyzed by histology and scored centrally according to the NASH Cli

95 AOM had reduced liver injury as assessed by histology and serum transaminase levels compared with C5

96 ily members were used for analysis of muscle histology and ultrastructure, mtDNA sequencing, and RNA

97 ogic and hepatic functions, as well as liver histology and ultrastructure.

98 NT tumors, which showed distinct metaplastic histology and worse survival.

99 ive methods, and associations among markers, histologies, and molecular subtypes were analyzed.

100 cult to compare TMB values across platforms, histologies, and treatments.

101 fallopian tube), underlying genetic defects, histology, and biologic behavior of human HGSCs have bee

102 s; patients with de-novo metastases, lobular histology, and bone-only disease; patients with visceral

103 ncluded assessment of adverse events, airway histology, and changes in symptoms using the Chronic Obs

104 ata were collected from mice and analyzed by histology, and cytokine levels were measured in serum sa

105 to use transcriptional profiling, virology, histology, and echocardiograms to investigate the role o

106 by increased lung collagen deposition, lung histology, and elevated pulmonary Th1/Th2 cytokine level

107 native biotin, comparative tests using PET, histology, and ICPMS.

108 We used flow cytometry, histology, and immunofluorescence to characterize CD8 ef

109 In vivo fluorochrome labeling, histology, and immunohistochemical analyses indicated th

110 used synchrotron X-ray fluorescence imaging, histology, and immunohistochemistry to compare the iron

111 y enzyme-linked immunosorbent assay (ELISA), histology, and immunohistochemistry.

112 in aorta cryosections using autoradiography, histology, and immunostaining.

113 ation, preserved skeletal and cardiac muscle histology, and improved strength and heart function foll

114 y sound, must produce images consistent with histology, and must yield qualitatively similar images w

115 tratumor heterogeneity, pathway alterations, histology, and overall survival.

116 regenerative medicine of the knee with MRI, histology, and Prussian blue staining.

117 rtery SMCs, with single-cell RNA-sequencing, histology, and RNAscope in an SMC-specific lineage-traci

118 Combining immunohistochemistry, histology, and synchrotron microtomography, we reconstru

119 explains the association between panel size, histology, and TMB threshold with panel performance and

120 Here, using numerous vertebral series, histology, and X-ray computed tomography, we provide a d

121 Our "molecular histology" approach could support stratifying patients f

122 Alterations in placental histology are frequently reported in these pregnancy com

123 y, we observed that age, family history, and histology are imprecise clinical correlates of LS-EC.

124 IN (100%) vs. cancer (100%) when compared to histology as the gold standard.

125 In this multicenter study, donor kidney histology assessment during allocation did not provide s

126 and after treatment along with paired liver histology assessment.

127 and micro-computed tomography (micro-CT) and histology assessments were carried out on day 28.

128 By histology, astrocytic plaques are diagnostic of CBD(7,8)

129 rom Jerzy Kreiner's myeloarchitectonic-based histology atlas.

130 Renal histology, available in 55 patients, showed tubulointers

131 organization and interactions, we developed Histology-based Digital-Staining, a deep learning-based

132 Computational histology-based stromal phenotypes within the tumor micr

133 Using histology-based three-dimensional technology, we demonst

134 in constituent area fractions obtained from histology but emphasize the complexity of lesion morphol

135 MRI and PET demonstrated good agreement with histology but native T(1) underestimated infarct size.

136 ysiology of Covid-19, extending conventional histology by a third dimension and allowing for full qua

137 d up and may reduce the cost of conventional histology by several orders of magnitude.

138 were associated with LC risk, overall and by histology, by leveraging resources from five prospective

139 In particular, histology can be used to study brain tissue at the micro

140 dimension for transferring all cultures to a histology cassette in order.

141 IPI was studied using histology (Chiu score, Alcian blue staining), Western bl

142 ion of biomarkers that include age and tumor histology classified by age-linked International Neurobl

143 Renal function and histology, complement activation, and expression of kidn

144 hickness of stent strut coverage by OCT with histology confirmation.

145 Histology confirmed bone growth inside the porous 3D sca

146 ssociation of ART, CD4+ count, or HIV PVL on histology-confirmed CIN2+ detection at follow-up.

147 Tumor recurrence was histology-confirmed in 40% (28/70) of patients.

148 gene expression was performed using standard histology, confocal imaging with three-dimensional analy

149 Two-patients had histology consistent with inflammation and a subsequentl

150 ABMR histology corresponds to a robust intragraft transcripti

151 Histology corroborates the organic composition of these

152 by any routine BTB tests (BOVIGAM, necropsy, histology, culture, PCR) that are regularly performed by

153 wo mouse models (OA and OPOA), and conducted histology, cytology, and molecular analyses.

154 resistant starch is associated with reduced histology damage in animal studies, and improvements in

155 Model parameters can be tuned from histology data, including relative vascular volume, mean

156 Improvement in liver histology, defined as decrease in nonalcoholic fatty liv

157 f contractile impairment was proportional to histology-defined myocardial macrophage density on day 8

158 s: Of the 216 biopsies with PET/CT guidance, histology demonstrated 170 lesions (78.7%) to be maligna

159 Projecting the histology-derived MTL model to in-vivo functional MRI, w

160 Actionability rates differed among histologies (eg, > 35% for urothelial cancers and < 6% f

161 structural, and compositional analyses using histology, electron microscopy, and Raman spectroscopy.

162 contain inorganic compounds throughout their histology, enclose preserved cellulosic remains in place

163 No patients with MBEN histology experienced relapse.

164 8)Ga-PSMA PET/CT findings were compared with histology findings in radical prostatectomy patients und

165 We used the term ABMR histology for biopsy specimens that fulfill the first tw

166 Colon tissues were analyzed by histology for the presence of collagenolytic colonies an

167 s were assessed by serum biochemistry, liver histology, gene expression, and western blot characteriz

168 pplied the Adipocyte U-Net to 4 cohorts with histology, genetic, and phenotypic data (total N = 820).

169 s involve multiple potentially heterogeneous histologies, guidance is needed to navigate the challeng

170 Histology, haematology and biochemical analysis of urine

171 Complementing MRI with histology has important applications in ex vivo atlas bu

172 The pSCC histology identifies 4NQO-induced tongue cancers that ar

173 In histology/image-negative disease, elevated NETest may re

174 Whole-slide histology images contain information that is valuable fo

175 Biodistribution data, tumor histology images, spheroid experiments, in vivo single-c

176 ly derive mean adipocyte area estimates from histology images.

177 y enumeration of tissue-associated bacteria, histology, immunofluorescence microscopy and scanning el

178 of mice, and colon tissues were analyzed by histology, immunofluorescence, and immunoblots.

179 Colon tissues were collected and analyzed by histology, immunofluorescence, xMAP, and reverse-transcr

180 Pancreata were collected and analyzed by histology, immunohistochemistry, and (single-cell) RNA s

181 tinal tissues were collected and analyzed by histology, immunohistochemistry, and flow cytometry.

182 ues were collected from mice and analyzed by histology, immunohistochemistry, and quantitative real-t

183 lled Mtg16), and derived their organoids, by histology, immunohistochemistry, and RNA sequencing (RNA

184 and lung tissues from mice were analyzed by histology, immunohistochemistry, and/or quantitative pol

185 esophageal and stomach tissues and performed histology, immunohistochemistry, flow cytometry, transcr

186 ssues and mouse macrophages were analyzed by histology, immunohistochemistry, immunoblots, and quanti

187 Iron validation techniques used include histology, immunohistochemistry, spectrometry and spectr

188 Samples were analyzed by histology, immunohistochemistry, western blotting, and p

189 Variant histologies in tumour tissues that have developed distin

190 Finally, we explored the individual cancer histologies in which these genomic alterations are most

191 results of multimodal imaging with those of histology in a case of Hurler syndrome-associated kerato

192 Vitamin E improves liver histology in adults with nonalcoholic steatohepatitis (N

193 pression levels correlated with non-mucinous histology in early stage cancers but not with other clin

194 Intestinal tissues were analyzed by histology, in situ hybridization, proliferation assays,

195 d at a younger age, enriched for WHO grade I histology, infrequently progressed, and rarely resulted

196 ng that screening strategies should focus on histology instead.

197 tion of bioanalytes with their corresponding histologies is the landmark feature of matrix-assisted l

198 Outcome after ABMR histology is not solely determined by the histomolecular

199 Skin histology is traditionally carried out using two-dimensi

200 helial carcinoma or rare genitourinary tract histologies, Karnofsky performance scale index of 60% or

201 o types based on differences in ontogeny and histology: legume-type and actinorhizal-type nodules.

202 atures were defined by bulky tumors, variant histology, lymphovascular invasion, hydronephrosis and/o

203 ify injury even before it becomes visible on histology, making it possible to start treatment at the

204 d RNA-sequencing (RNA-seq) data with spatial histology mapped by deep learning in 100 patients with n

205 graphy (XPCT), providing virtual slices with histology-matching resolution.

206 Compared with standard histology, multimodal imaging allowed additional keratoc

207 We compared kidney histology, neutrophil functions, T cell proliferation an

208 hs of age, when all mice had normal prostate histology, Nkx3.1(+/-) mice demonstrated indices of meta

209 carcinoma metastases and patients with rare histologies of the genitourinary tract) were exploratory

210 on-HLA antibodies and their association with histology of AMR (AMRh) and kidney allograft failure.

211 ing for clinical value in patients with this histology of breast cancer.

212 etabolism, insulin tolerance test (ITT), and histology of cardiac structure at the endpoint.

213 Histology of heart sections included hematoxylin-eosin s

214 A specialized pathologist then analyzed the histology of the detected lesions.

215 ine with previous findings using post-mortem histology of the human substantia nigra and radiotracer

216 In both the father and the aunt, histology of the surgical specimen revealed a diffuse gr

217 Histology of tumor sections corroborated QSM visualizati

218 The primary endpoint, cervical HSIL by histology or cytology at either week 26 or 52, was compa

219 2 small adenomas (<1cm, and without villous histology or high-grade dysplasia) and no neoplasia, res

220 ed as adenomas >=10mm, adenomas with villous histology or high-grade dysplasia, or colorectal cancer

221 Verification of sex via histology or laparoscopy revealed that this method was 1

222 Mycological criteria included positive histology or microscopy, positive BAL fluid culture, gal

223 d an advanced adenoma (adenoma with advanced histology or polyp >=10 mm), and 2.6% were diagnosed wit

224 al [CI], 2.34-61.45; P = 0.003), monomorphic histology (OR, 10.63; 95% CI, 1.88-60.25; P = 0.008), mu

225 nner, but did not change TSH levels, weight, histology, or expression of marker genes of the thyroid

226 Patients of any age, sex, histology, or stage were considered eligible, including

227 5) are more predictive of the post-operation histology outcome than Clinical signs (Pseudo R-Square =

228 7) are more predictive of the post-operation histology outcome than MRI tests (Pseudo R-Square = 0.05

229 tched cohort study, comparing post-operative histology outcomes (benign versus non-benign) versus 15

230 howed a significant correlation with ex vivo histology (p < 0.001) and also corresponded well to indu

231 itis, and antibody markers within concurrent histology (P < 0.001).

232 lder than 12 months of age (P = .036) and ND histology (P = .005) were associated with worse PFS.

233 ommendations are conditional on the basis of histology, PD-L1 status, and/or the presence or absence

234 When adjusted for age, stage, and histology, pelvic lymph node TLG, PALN TLG, and PALN SUV

235 Histology performed on surgical specimens served as the

236 In histology-positive, the NETest accuracy was 100% (25/25)

237 ryonal carcinoma was the most frequent RPLND histology, present in 143 patients (92%).

238 Brain and eyes histology presented severe damage in the bilateral group

239 with an ORR of 38% (P < .0001) in this mixed histology, pretreated cohort.

240 T) at 52 weeks, for improvement in (1) liver histology primary outcome, (2) borderline zone 1 NASH, a

241 tome sectioning, the TTA allows for parallel histology processing for the entire samples cultured in

242 spheroids suggests a remarkable reduction in histology processing time by an order of magnitude.

243 , which were confirmed by immunostaining and histology qualitatively, and biochemistry assays and gen

244 Colon and tumor tissues were analyzed by histology, quantitative polymerase chain reaction, and 1

245 objective responses in patients with variant histology RCC or RCC with >= 20% sarcomatoid differentia

246 erentiation and 26% in patients with variant histology RCC.

247 The stage changes varied by tumor histology, receptor status, tumor grade, and Oncotype DX

248 We present results on 3D histology reconstruction of whole human hemispheres from

249 putational pipeline to produce 3D consistent histology reconstructions of the human brain.

250 kx3.1 protein, reduced prostate size, normal histology, reduced proliferation, and increased DNA end

251 However, histology requires sectioning tissue, hence distorting i

252 tus at sampling was assessed by gastroscopy, histology (resection margin [R] positivity of polypectom

253 307 women (median age, 36 years) with valid histology results and triple-matched urine, self-collect

254 Histology revealed abnormal intimal and medial thickenin

255 anularity, white spots, and furrowing, while histology revealed oedema, immune cell infiltration, and

256 different cell types during regeneration by histology, RNA sequencing, and flow cytometry.

257 Histology, scanning electron microscopy, and nanoindenta

258 These patients underwent medical record, EoE Histology Scoring System, Endoscopic Reference Score, an

259 The corresponding histology sections exhibit only minimal collateral damag

260 ecause of its high performance in tasks like histology segmentation.

261 Combining conventional diagnostics (histology, serology, and clinical data) and molecular ev

262 The final surgical histology served as the standard of reference.

263 Histology showed infiltration of inflammatory cells incl

264 Histology showed irregular orientation and organization

265 Biopsy specimens with ABMR histology showed overexpression of transcripts mostly re

266 Testis histology showed rainbowfish spermatogonia are large (>

267 AD versus wild-type mice correlate well with histology, showing promise for a fast and practical in v

268 their human counterparts judging from their histology, size, and marginal tendency to progress.

269 logical samples such as cell culture, tissue histology slices, or living subjects.

270 ect MSI and dMMR in tumor samples on routine histology slides faster and less expensively than molecu

271 ntial for extracting molecular features from histology slides has yet been performed.

272 Five had a histology specimen.

273 atient overall survival included epithelioid histology, T stage, quantitative clinical stage/tumor vo

274 tologic rejection showed less agreement with histology than unsupervised R2(TCMR) scores.

275 We explain the role of histology that defines subtypes of myocarditis and its p

276 For improvement in histology, the model (P < 0.0001) retained baseline and

277 For histology, the pooled prevalence estimate of anal squamo

278 ransformation from a prostate adenocarcinoma histology to a castration-resistant neuroendocrine prost

279 oss-sectional images were co-registered with histology to determine the optimal cutoff value for stru

280 x 1 mm) were coregistered with postoperative histology to determine tissue types present in each scan

281 ing global and local measures of the muscles histology to quantify changes in muscle phenotype, micro

282 A tool to enable in vivo histology to quickly and quantitatively distinguish betw

283 cipients at two French centers, adding donor histology to the model did not significantly improve pre

284 ypic characteristics across a range of tumor histologies using a validated, high-resolution digital m

285 tionship between liver chemistries and liver histology using data from the CyNCh (Cysteamine Bitartra

286 accuracy was evaluated by the agreement with histology using weighted Kappa.

287 Histology was correlated with spectral-domain optical co

288 There were 223 males, median age was 69 and histology was epithelioid in 184.

289 nomic alterations associated with clear-cell histology, we found that Hippo was one of the most frequ

290 Of these, the histologies were colorectal adenocarcinoma (N = 1) and b

291 The most frequent histologies were osteosarcoma (n = 6), inflammatory myof

292 dvanced renal cell carcinoma with clear cell histology were enrolled in 129 sites (hospitals and canc

293 rmatory study to validate this definition by histology which is the gold standard.

294 V16 D2 and D3 sublineages harboring distinct histology, which may help guide future therapeutic strat

295 Imaging results were validated by H&E histology, which showed evidence of remodeling of arteri

296 dentify those patients, independent of tumor histology, who would benefit from treatment with a MAP k

297 ficantly boosted performance: improvement in histology with AUROC of 0.89 (95% CI, 0.82-0.95), border

298 n to micro-computed tomography (microCT) and histology with fluorescent dextran tracers.

299 d EIT images correspond to microCT scans and histology, with significant separation between the fasci

300 It is unclear whether cases involving ABMR histology without detectable HLA-DSAs represent a distin