ライフサイエンスコーパス: histone acetyltransferase

1 er protein of H3K36me3, and the KAT5 (TIP60) histone acetyltransferase.

2 sed and was essentially mediated by the p300-histone acetyltransferase.

3 lation were associated tightly with EP300, a histone acetyltransferase.

4 romoter (-98 to -94) and recruiting the p300 histone acetyltransferase.

5 understanding the structure/function of non-histone acetyltransferases.

6 h can be used to identify substrate sites of histone acetyltransferases.

7 obvious similarities between TAF1 and known histone acetyltransferases.

8 , including the transcription factor p53 and histone acetyltransferases.

9 with sequence similarity to the GCN5 family histone acetyltransferases.

10 d by epithelial growth factor, we identified histone acetyltransferase 1 (HAT1) as an induced gene th

11 -B is a multisubunit complex composed of the histone acetyltransferase 1 (Hat1) catalytic subunit and

12 Histone acetyltransferase 1 (Hat1) catalyzes the acetyla

13 Histone acetyltransferase 1 (HAT1) is responsible for th

14 Histone acetyltransferase 1 (HAT1), which catalyzes H4K5

15 We also uncovered the histone acetyltransferase 1 (HAT1)-RBBP7 lysine acetylas

16 s acetylated at lysine 5 and 12 (H4K5,12) by histone acetyltransferase 1 (HAT1).

17 1.9-A resolution crystal structure of human histone acetyltransferase 1 in complex with acetyl coenz

18 Histone acetyltransferase 1 is the founding member of th

19 ther govern substrate-binding specificity of histone acetyltransferase 1.

20 ; guanylate cyclase 1, soluble, beta 3; MYST histone acetyltransferase 1; protein phosphatase 3 (form

21 tion with its reciprocally imprinted ligand, histone acetyltransferase-1 (HAT1), a gene involved in c

22 This enables recruitment of the p300 histone acetyltransferase, a domain-wide increase in his

23 Mechanistically, p300-histone acetyltransferase acetylates STAT3, which, in tu

24 One member of the complex, MOF, a histone acetyltransferase, acetylates lysine 16 of histo

25 In embryonic stem cells (ESCs), the Tip60 histone acetyltransferase activates genes required for p

26 ylase inhibitor to determine the rate due to histone acetyltransferase activity alone and in the abse

27 e histone acetyltransferase enzyme p300, and histone acetyltransferase activity and histone acetylati

28 ranscriptional corepressor with inhibitor of histone acetyltransferase activity and is a potent suppr

29 nd -b and global DNA methylation and reduced histone acetyltransferase activity and TET1, -2, and -3

30 TAF7 acts as a dissociable inhibitor of TAF1 histone acetyltransferase activity and that this event e

31 This caused a significant decrease in Gcn5 histone acetyltransferase activity in vitro and in vivo

32 In addition, inhibition of histone acetyltransferase activity of P300 significantly

33 rsor proliferation was rescued by inhibiting histone acetyltransferase activity or expressing HDAC3.

34 hat a primary function of ATF4 is to recruit histone acetyltransferase activity to a sub-set of AAR t

35 ing, phospho-Ser 2 RNA Pol II formation, and histone acetyltransferase activity.

36 Such a function is mediated via its targeted histone acetyltransferase activity.

37 atible assay that measures the inhibition of histone acetyltransferase activity.

38 al control nonderepressible 5, which display histone acetyltransferase activity.

39 ure at promoters in eukaryotic cells via MOZ histone acetyltransferase activity.

40 ry and fibrogenic genes through its atypical histone acetyltransferase activity.

41 B-RNA polymerase II complex and inhibits its histone acetyltransferase activity.

42 ting RNA polymerase II, and by its intrinsic histone acetyltransferase activity.

43 REBBP) are transcriptional coactivators with histone acetyltransferase activity.

44 t that CSRP2BP, a coactivator for CRP2, is a histone acetyltransferase and a driver of smooth muscle

45 These acetylations require the Gcn5 histone acetyltransferase and are reversed by the sirtui

46 ity, we identified an essential role for the histone acetyltransferase and deubiquitinase SAGA comple

47 firm that nucleosomal H3K4me3 stimulates the histone acetyltransferase and H2Av exchange activities o

48 Using histone acetyltransferase and methyltransferase inhibito

49 Our work illustrates a causal role of histone acetyltransferases and acetylation in senescence

50 ensitivity to depletion and/or inhibition of histone acetyltransferases and CDK9 and less sensitivity

51 tion of histones and non-histone proteins by histone acetyltransferases and deacetylases (HDACs) play

52 factor Sp1, with commensurate recruitment of histone acetyltransferases and deacetylases, increased h

53 on residue T34 upregulates the activities of histone acetyltransferases and deacetylases, which then

54 on residue T34 upregulates the activities of histone acetyltransferases and deacetylases.

55 27ac), which correlated with the presence of histone acetyltransferases and deacetylases.

56 y, we ectopically overexpressed 21 different histone acetyltransferases and found that KAT6A, KAT6B a

57 tion status is modulated antagonistically by histone acetyltransferases and histone deacetylases (HDA

58 ion, is controlled by the opposing action of histone acetyltransferases and histone deacetylases (HDA

59 Histone acetyltransferases and histone deacetylases (HDA

60 d because of the limited specificity of most histone acetyltransferases and histone deacetylases.

61 ction of Elk-1 with co-activators, including histone acetyltransferases and the Mediator complex.

62 ow that suppressor of Ty (Spt)10, a putative histone acetyltransferase, and its binding partner Spt21

63 itional pentanoate-originated acetyl-CoA for histone acetyltransferases, and by pentanoate-triggered

64 The three histone acetyltransferases are MOZ, MORF, and HBO1, whic

65 Taybi syndrome (caused by mutations in other histone acetyltransferases) are discussed.

66 BRPF1 encodes a protein modifier of two histone acetyltransferases associated with ID: KAT6A (al

67 s well as peaks of acetylated H4K16 and KAT8 histone acetyltransferase at the transcription start sit

68 Levels of some histone acetyltransferases at this gene (PCAF and MOF) w

69 ons by disrupting the histone deacetylase-to-histone acetyltransferase balance in the nucleus.

70 Histone acetyltransferase binding to origin recognition

71 dicating that another as of yet unidentified histone acetyltransferase binds to SMAD3 at PLOD2.

72 lation leads to a specific activation of the histone acetyltransferase Brd2, which results in histone

73 TAT1 has an overall fold similar to the Gcn5 histone acetyltransferase but contains a relatively wide

74 hanced on nucleosomes acetylated by the NuA4 histone acetyltransferase, but recognition of nucleosome

75 GNATs are known for their role as histone acetyltransferases, but non-histone bacterial pr

76 l activity stimulates binding of IPMK to the histone acetyltransferase CBP and enhances its recruitme

77 1; cec-4 mutants is rescued by depleting the histone acetyltransferase CBP-1/p300 or the transcriptio

78 e acetylation associated with recruitment of histone acetyltransferase CBP.

79 (MLL) histone methylases (MLL2 and MLL3) and histone acetyltransferase CBP/P300 bind to the EZH2 prom

80 The histone acetyltransferases CBP/p300 are involved in recu

81 Inhibition of histone acetyltransferases CBP/p300 relieves the HMGN1-a

82 nt a small-molecule (TTK21) activator of the histone acetyltransferases CBP/p300, which, when conjuga

83 Kat2a is a histone acetyltransferase central to promoter activity,

84 data reveal how transcriptional regulators, histone acetyltransferases, chromatin remodelers, and tr

85 L2 suppressed this process by inhibiting the histone acetyltransferase coactivator p300, preventing t

86 The evolutionarily conserved histone acetyltransferase complex Elongator was identifi

87 this study, we show that the conserved Mst2 histone acetyltransferase complex in fission yeast regul

88 ic interactions with mutations affecting the histone acetyltransferase complex NuA4, vps15Delta and v

89 ex, instead, functions as an ATP-independent histone acetyltransferase complex similar to the yeast N

90 he NuA4, nucleosome acetyltransferase of H4, histone acetyltransferase complex, (ii) the switching de

91 We identified components of the SAGA histone acetyltransferase complex, in particular Gcn5, a

92 lation, likely through interactions with the histone acetyltransferase complex.

93 sion are alleviated by mutations of the SAGA histone acetyltransferase complex.

94 FD1 interactors were components of the TIP60 histone acetyltransferase complex.

95 Ada3 (ADA) and Esa1-Yng2-Epl1 (Piccolo NuA4) histone acetyltransferase complexes have the capacity to

96 yeast and humans, nucleosome remodeling and histone acetyltransferase complexes originate from gene

97 mplexes, including the Mediator and multiple histone acetyltransferase complexes, among which are the

98 folding protein required for the assembly of histone acetyltransferase complexes, where the gene of M

99 al tail lysine residues by the NuA4 and SAGA histone acetyltransferase complexes.

100 actor 4-like 1 (MORF4L1) is a relatively new histone acetyltransferase component that exists as a hom

101 nd K148Q, abolished its self-assembly of the histone acetyltransferase component.

102 g protein (p38IP) is a component of the GCN5 histone acetyltransferase-containing coactivator complex

103 ent binding (CREB) interaction domain of the histone acetyltransferase CREB-binding protein (CBP).

104 overexpression of HDAC8 or knocking down the histone acetyltransferase CREB-binding protein/p300, kno

105 riched for the activating marker H3K27ac and histone acetyltransferase CREBBP after MED25 overexpress

106 Plants treated with an inhibitor of histone acetyltransferases, curcumin, previous to the UV

107 3 is involved in histone acetylation via its histone acetyltransferase domain (HAT) and, as a result,

108 38IP N terminus (1-381 amino acids) and GCN5 histone acetyltransferase domain and bromodomain.

109 Rescue experiments with a MOF histone acetyltransferase domain mutant illustrated the

110 and pRb into a ternary complex, bringing the histone acetyltransferase domain of CBP/p300 into proxim

111 itative mass spectrometry, we identified the histone acetyltransferase domain of HBO1 as being essent

112 nd that Fos eRNAs directly interact with the histone acetyltransferase domain of the enhancer-linked

113 Current inhibitors of the p300 and CBP histone acetyltransferase domains, including natural pro

114 olangiocytes and uncovered that ETS1 and the histone acetyltransferase E1A-binding protein P300 (EP30

115 Once in the nucleus, sSDC1 binds to the histone acetyltransferase enzyme p300, and histone acety

116 mechanistically, far less is known about non-histone acetyltransferase enzymes.

117 , chronic stress increased expression of the histone acetyltransferase EP300 and increased histone ac

118 In turn, Hdac3 recruited histone acetyltransferase Ep300 to form an enhanceosome

119 acetylases and concurrent recruitment of the histone acetyltransferase EP300 to MEF2 target gene regu

120 rs and enhancers together with SMAD3 and the histone acetyltransferase EP300, enabling transcription

121 somal rearrangements of the ZNF384 gene with histone acetyltransferases EP300 and CREBBP ZNF384-rearr

122 with strongest differences for TP53 and the histone-acetyltransferase EP300.

123 through its interaction with the MYST family histone acetyltransferase Esa1.

124 eases Acetyl-CREB-binding protein (CBP/p300) histone acetyltransferase expression in a time and dose-

125 On the other hand, PAF increased p300 histone acetyltransferase expression, and the acetylatio

126 RTT109 is a histone acetyltransferase for histone H3 lysine 56 (H3K5

127 - and chromatin-related genes, including the histone acetyltransferases for H3K27ac and H3K9ac.

128 ous studies have shown perturbations in SAGA histone acetyltransferase function and transcriptional a

129 Li et al. now show that Mof, a MYST family histone acetyltransferase, functions as a coactivator of

130 ere significantly inhibited by inhibitors of histone acetyltransferase (garcinol and antisense agains

131 The histone acetyltransferase GCN5 (general control non-repr

132 /36/37 residues, which specifically recruits histone acetyltransferase GCN5 for subsequent H3 acetyla

133 tz1 inherently enhances the occupancy of the histone acetyltransferase Gcn5 on chromatin to promote h

134 The Arabidopsis thaliana histone acetyltransferase GCN5 regulates histone modific

135 d upon deletion of the previously implicated histone acetyltransferase Gcn5, but G1/S cell cycle regu

136 cific, conditional knockout mice for the key histone acetyltransferase Gcn5, which resulted in abnorm

137 Using the yeast histone acetyltransferase Gcn5p as a case study, we demo

138 on at sites of injury, paralleling increased histone acetyltransferase general transcription factor I

139 lators, including histone chaperones and the histone-acetyltransferase general control nonderepressib

140 and positively with DOG1 expression, as were histone acetyltransferase genes, with histone deacetylas

141 The monocytic leukemic zinc finger (MOZ) histone acetyltransferase (HAT) acetylates free histones

142 igenetic regulator with intrinsic kinase and histone acetyltransferase (HAT) activities that activate

143 actor 1 (TAF1), possesses protein kinase and histone acetyltransferase (HAT) activities.

144 iptional coactivator p300/CBP possesses both histone acetyltransferase (HAT) activity and scaffolding

145 Loss of the histone acetyltransferase (HAT) activity blocks oogenesi

146 pplementation; this microRNA alters HDAC and histone acetyltransferase (HAT) activity, which suggests

147 e exhibited increased renal HDAC and reduced histone acetyltransferase (HAT) activity; on the contrar

148 contains two enzymatic modules, which house histone acetyltransferase (HAT) and deubiquitinase (DUB)

149 Gcn5 and sirtuins are highly conserved histone acetyltransferase (HAT) and histone deacetylase

150 Chromatin remodeling through histone acetyltransferase (HAT) and histone deactylase (

151 Using steady-state histone acetyltransferase (HAT) assays, we show that an

152 We find that the histone acetyltransferase (HAT) Chameau (Chm) binds to a

153 Previous studies have established that the histone acetyltransferase (HAT) complex Hat1p/Hat2p medi

154 Brd1 is a subunit of the Hbo1 histone acetyltransferase (HAT) complex responsible for

155 Piccolo NuA4 is an essential yeast histone acetyltransferase (HAT) complex that targets his

156 udor domain of PHF20, which recruits the MOF histone acetyltransferase (HAT) complex to ERalpha targe

157 n PHD finger 1) is a core subunit of the MOZ histone acetyltransferase (HAT) complex, critical for no

158 mine tract in ATXN7, a component of the SAGA histone acetyltransferase (HAT) complex.

159 The lysine acetyltransferase 6 (KAT6) histone acetyltransferase (HAT) complexes are highly con

160 ed factor] and MOZ are catalytic subunits of histone acetyltransferase (HAT) complexes essential in h

161 SEs of the multisubunit Mediator and several histone acetyltransferase (HAT) complexes, including Spt

162 (ADA3) is an essential component of specific histone acetyltransferase (HAT) complexes.

163 of several transcriptional co-activator and histone acetyltransferase (HAT) complexes.

164 tations in several subunits of SAGA and NuA4 histone acetyltransferase (HAT) complexes.

165 of the Notch-binding region of MAML1 to the histone acetyltransferase (HAT) domain of p300 rescues e

166 The histone acetyltransferase (HAT) family of proteins perfo

167 tein microarray analysis that identified the histone acetyltransferase (HAT) Hbo1 as a novel cyclin E

168 en Phytophthora sojae acts as a modulator of histone acetyltransferase (HAT) in plants.

169 e ability of garcinol, a naturally-occurring histone acetyltransferase (HAT) inhibitor derived from t

170 The histone acetyltransferase (HAT) inhibitor garcinol or ve

171 Several histone acetyltransferase (HAT) inhibitors with these li

172 or-binding Tra1 module, the core module, the histone acetyltransferase (HAT) module and the histone d

173 contains a separable subcomplex known as the histone acetyltransferase (HAT) module that contains the

174 The histone acetyltransferase (HAT) Mof is essential for mou

175 In this manner, we discovered the H4K16 histone acetyltransferase (HAT) MOF to be important for

176 Histone acetyltransferase (HAT) p300 and its paralog CBP

177 , 2020 report that PCAF is a fork-associated histone acetyltransferase (HAT) that regulates the stabi

178 The histone acetyltransferase (HAT) Tip60 epigenetically reg

179 Besides the primary histone acetyltransferase (HAT)-mediated chromatin remod

180 se (HDA) and (2) auxin response factor (ARF)-histone acetyltransferase (HAT).

181 se (HDA) and (2) auxin response factor (ARF)-histone acetyltransferase (HAT).

182 Histone modifications, largely regulated by histone acetyltransferases (HAT) and histone deacetylase

183 Here, we identify a trypanosome histone acetyltransferase (HAT3) and a deacetylase (SIR2

184 acetylation state of histones, controlled by histone acetyltransferases (HATs) and deacetylases (HDAC

185 , maintained by the antagonistic activity of histone acetyltransferases (HATs) and histone deacetylas

186 n of histones by chromatin-modifying enzymes histone acetyltransferases (HATs) and histone deacetylas

187 ected histone lysine residues is governed by histone acetyltransferases (HATs) and histone deacetylas

188 Histone acetyltransferases (HATs) and histone deacetylas

189 rsible acetylation of proteins, catalysed by histone acetyltransferases (HATs) and histone deacetylas

190 KAT6 histone acetyltransferases (HATs) are highly conserved i

191 KAT6 histone acetyltransferases (HATs) are highly conserved i

192 ether other histone deacetylases (HDACs) and histone acetyltransferases (HATs) are involved in MSH2 d

193 transformation requires interaction with the histone acetyltransferases (HATs) CBP/p300 and now repor

194 The genes encoding the histone acetyltransferases (HATs) CREBB-binding protein

195 Although histone acetyltransferases (HATs) have been well charact

196 sequencing to screen the levels of all known histone acetyltransferases (HATs) in the hippocampal CA1

197 The MYST family of histone acetyltransferases (HATs) plays critical roles i

198 ted 300 kDa protein) are two closely related histone acetyltransferases (HATs) that play a key role i

199 We assess the ability of seven histone acetyltransferases (HATs) to catalyze acylations

200 nstrated using pharmacological inhibitors of histone acetyltransferases (HATs).

201 This process is controlled by histone acetyltransferases (HATs/KATs) found in multipro

202 Lysine acetyltransferases (KATs, also termed histone acetyltransferases, HATs) catalyze the acetylati

203 Whereas histone acetyltransferases have been extensively studied

204 erones, nucleosome remodeling complexes, and histone acetyltransferases have been implicated in nucle

205 MYST histone acetyltransferases have crucial functions in tra

206 modifiers such as DNA methyltransferases and histone acetyltransferases have revealed a critical role

207 Histone acetyltransferase HBO1 might acetylate this resi

208 total HDAC activity but increased the total histone acetyltransferase/HDAC activity ratio in mouse l

209 l HDAC activity, and it diminished the total histone acetyltransferase/HDAC activity ratio in mouse l

210 sferases, ten-eleven translocation proteins, histone acetyltransferases, histone deacetylases, BET br

211 The MYST family histone acetyltransferase hMOF (human MOF) is responsibl

212 other anti-silencing factors, including the histone acetyltransferase IDM1 and the alpha-crystallin

213 , we set out to investigate whether the main histone acetyltransferases in budding yeast, Gcn5 and Es

214 histone acetylation marks and for different histone acetyltransferases in long-range gene regulation

215 ly, prevention of histone acetylation by the histone acetyltransferase inhibitor curcumin diminished

216 We conclude that the CSRP2BP histone acetyltransferase is a coactivator for CRP2 that

217 CT 116 cells lacking p300 suggested that the histone acetyltransferase is a negative regulator of Hip

218 association, and a shortened isoform of Mst2 histone acetyltransferase is expressed.

219 The MYST family of histone acetyltransferases is autoacetylated at an activ

220 by complexes containing opposing lysine and histone acetyltransferase (KAT and HAT) and deacetylase

221 letion of the ubiquitin ligase HUWE1, or the histone acetyltransferase KAT5, top hits from our screen

222 ORC to the origin, suggesting that multiple histone acetyltransferases may be recruited during origi

223 Here, we show that histone acetyltransferase MOF plays a critical role in t

224 Histone acetyltransferase mortality factor 4-like 1 (MOR

225 The histone acetyltransferase MOZ (MYST3, KAT6A) is the targ

226 scription regulation in combination with the histone acetyltransferase NuA4 and histone H2A.Z exchang

227 ng proteins important for the recruitment of histone acetyltransferases of the MYST family to chromat

228 ng proteins important for the recruitment of histone acetyltransferases of the MYST family to chromat

229 Mechanistically, Wnt3a does not alter histone acetyltransferase or deacetylase activities but,

230 tion is accomplished by a dominant action of histone acetyltransferases over repressive histone-modif

231 on of AKT signaling, which in turn activates histone acetyltransferase p300 (p300 HAT), leading to ch

232 e strongly to the transcriptional regulators histone acetyltransferase P300 (p300), NFkappaB, and CCA

233 l roles in protein activation, including the histone acetyltransferase p300 acetylated in its activat

234 cts with the transcriptional coactivator and histone acetyltransferase p300 and activates gene expres

235 ough certain chromatin features, such as the histone acetyltransferase P300 and the histone modificat

236 f different epigenetic modifiers showed that histone acetyltransferase p300 could enhance both TALE-V

237 own of GATA6 or transcriptional co-activator/histone acetyltransferase p300 decreased AQP5 expression

238 The histone acetyltransferase p300 has been implicated in th

239 Overexpression of the histone acetyltransferase p300 is implicated in the prol

240 Once HDAC1 is tethered, histone acetyltransferase p300 is no longer recruited to

241 The histone acetyltransferase p300 is normally associated wi

242 Consistent with this idea, the histone acetyltransferase p300 is recruited to organizer

243 al activators Sp1 and HIF-1 colocalized with histone acetyltransferase p300 on ncx1-Br with a consequ

244 ain interactions, whereas sites bound by the histone acetyltransferase p300 or the transcription fact

245 ated beta-HPV E6 protein suggesting that the histone acetyltransferase p300 plays a role in promoting

246 Furthermore, we found that histone acetyltransferase p300 supported the recruitment

247 dentified multiple new players including the histone acetyltransferase p300 that was found to be a pr

248 d-chromatin association, and associates with histone acetyltransferase p300 to enhance Smad transcrip

249 to the VMP1 promoter and complexes with the histone acetyltransferase p300 to regulate promoter acti

250 tylation upon HDAC inhibition, partly by the histone acetyltransferase p300, and that both NF-kappaB

251 ders Il9 locus accessible via recruitment of histone acetyltransferase p300, and together with inhibi

252 ding histone H3K4 methyltransferase SET1 and histone acetyltransferase p300, whose levels are also el

253 LL4 (H3K4 methyltransferase) complex and the histone acetyltransferase p300.

254 g of IL10 through their interaction with the histone acetyltransferase p300.

255 chromatin environment via recruitment of the histone acetyltransferase p300.

256 described E3 ligase function of BRMS1 on the histone acetyltransferase p300.

257 F-kappaB through direct interaction with the histone acetyltransferase p300.

258 rough systematic epigenetic studies that the histone acetyltransferase p300/CBP-associated factor (PC

259 Here, we identify a novel activity of the histone acetyltransferase p300/CREB-binding protein (CBP

260 acute degradation system, we found that the histone acetyltransferases P300 and CBP maintained H3K27

261 Furthermore, histone acetyltransferases p300 and P300/CBP-associated

262 eraction between the DUX4 C-terminus and the histone acetyltransferases p300/CBP.

263 On the molecular level, hG9a interacted with histone acetyltransferase, p300/CBP, resulting in increa

264 t H3K9 acetylation by the NeuroD1-associated histone acetyltransferase, P300/CBP-associated factor (P

265 II histone deacetylase (HDAC), HDAC4, and a histone acetyltransferase, p300/CREB-binding protein-ass

266 unctions by binding to the KIX domain of the histone acetyltransferase paralogues CREB-binding protei

267 The histone acetyltransferase paralogues p300 and CREB-bindi

268 Here, we report the histone acetyltransferase PCAF (p300/CBP-associated) as

269 The histone acetyltransferase PCAF-mediated acetylation and

270 Here, we show that the histone acetyltransferase PCAF/KAT2B is an important fac

271 acterization demonstrated that SMAD2 and the histone acetyltransferase, PCAF, participate in this reg

272 Interestingly, CBP, a histone acetyltransferase previously implicated in repre

273 ption by acting at an early step to regulate histone acetyltransferase recruitment, histone acetylati

274 Novel inhibitor of histone acetyltransferase repressor (NIR) is a transcrip

275 Loss of the histone acetyltransferase Rtt109 also suppressed ctk1-de

276 from two repairable DSBs also depends on the histone acetyltransferase Rtt109 and the cullin subunit

277 g high-throughput screen (HTS) targeting the histone acetyltransferase Rtt109 were such compounds.

278 genome-wide screen and demonstrated that the histone acetyltransferase SAGA and the activity of histo

279 fferent epigenetic marks and activates three histone acetyltransferases, so it is both a reader and a

280 ltransferase 1 is the founding member of the histone acetyltransferase superfamily and catalyzes lysi

281 nteraction between Arabidopsis MRE11 and the histone acetyltransferase TAF1, a TATA-binding protein A

282 Together, this study identifies the first histone acetyltransferase that activates ERalpha express

283 e ERalpha, suggesting MYST3 functioning as a histone acetyltransferase that activates ERalpha promote

284 Tat-interactive protein 60 (Tip60) is a MYST histone acetyltransferase that catalyses acetylation of

285 is a MOZ, Ybf2/Sas3, Sas2, Tip60 (MYST)-type histone acetyltransferase that functions as a coactivato

286 regulates the availability of acetyl-CoA for histone acetyltransferases, thus representing a link bet

287 normal compaction pathway is defective, the histone acetyltransferase Tip60 is recruited to pericent

288 The histone acetyltransferase TIP60 was previously shown to

289 Foxp3(gfp) was unable to interact with the histone acetyltransferase Tip60, the histone deacetylase

290 cell master regulator Foxp3 mediated by the histone acetyltransferase Tip60, which targeted Foxp3 fo

291 zymes including histone demethylase LSD1 and histone acetyltransferase Tip60.

292 monocytic leukemia zinc finger protein (MOZ) histone acetyltransferase to the viral promoter, which p

293 ction in Th9 cells by binding and recruiting histone acetyltransferases to the Il9 locus at sites dis

294 tion of these 2 CpGs impaired binding of the histone acetyltransferase/transcriptional coactivator p3

295 Many histone acetyltransferases undergo autoacetylation, eith

296 ocytic leukemia zinc finger protein (MOZ), a histone acetyltransferase, we demonstrate that mutation

297 selectively target the catalytic activity of histone acetyltransferases, which may provide effective

298 ne expression and identify KAT8 as the first histone acetyltransferase with an essential function in

299 functions as a platform for recruiting Tip60 histone acetyltransferase with increased H4 acetylation

300 Sustained association of NFAT and p300 histone acetyltransferase with the IP-10 gene required p