ライフサイエンスコーパス: histone-like

1 that the sigma factors also possess a linker histone-like activity in the formation of a prokaryotic

2 packaged with protein VII, a virally encoded histone-like core protein that is suggested to protect i

3 aging protein in yeast, like its prokaryotic histone-like counterpart, HU protein.

4 HU, a nonspecific histone-like DNA binding protein, participates in a numb

5 This study identified HP119 as a putative histone-like DNA-binding protein and showed that it play

6 anded-DNA-binding 12RNP2 precursor (HP0827); histone-like DNA-binding protein HU (HP0835); ribosomal

7 the pandemic clone of V. parahaemolyticus, a histone-like DNA-binding protein, HU-alpha, has a C-term

8 onstrates that the evolutionarily conserved, histone-like domain is sufficient and necessary to suppo

9 lterin proteins TRF1 or TRF2, also possess a histone-like domain which is involved in protein-protein

10 specific genes; rather, MeCP2 functions as a histone-like factor whose phosphorylation may facilitate

11 Lsr2 is a M. tuberculosis protein with histone-like features, including the ability to regulate

12 DL1 and CiNF-YB8 interact with the classical histone-like fold domain (HFD) of CiNF-YC1 and CiNF-YA3,

13 nts, including two novel human proteins with histone-like folds and sequence relationships to yeast S

14 including the ubiquitous HU proteins, serve histone-like functions in prokaryotes.

15 identity with the consensus sequence of the histone-like HB protein of Bacillus species.

16 The histone-like HU (heat unstable) protein plays a key role

17 pret new experimental data for the bacterial histone-like HU protein and two eukaryotic high-mobility

18 These data reveal histone-like modification cassettes - or "histone mimics

19 uence homologies and propose that an ancient histone-like motif in two CBF subunits controls the form

20 response sigma factor (sigmas), and H-NS, a histone-like nucleoid protein and global transcription r

21 reduction in levels of the global suppressor histone-like nucleoid structure protein, H-NS.

22 The histone-like nucleoid structuring (H-NS) protein is a DN

23 The histone-like nucleoid structuring (H-NS) protein plays a

24 tion from these promoters is silenced by the histone-like nucleoid structuring (H-NS) protein.

25 MucR is a recent addition to the family of histone-like nucleoid structuring (H-NS) proteins.

26 ors that participate in this process are the histone-like nucleoid structuring protein (H-NS) and the

27 The histone-like nucleoid structuring protein (H-NS) has bee

28 The histone-like nucleoid structuring protein (H-NS) is a DN

29 The histone-like nucleoid structuring protein (H-NS) is a nu

30 Histone-like nucleoid structuring protein (H-NS) is repr

31 We found that the histone-like nucleoid structuring protein (H-NS) selecti

32 hat are believed to facilitate DNA bridging: histone-like nucleoid structuring protein (H-NS), ParB,

33 erve as binding sites for the gene repressor histone-like nucleoid structuring protein (H-NS), we mea

34 -k to the non-specific DNA-binding domain of histone-like nucleoid structuring protein from Escherich

35 The histone-like nucleoid structuring protein H-NS and DNA s

36 also found to be structurally similar to the histone-like nucleoid structuring protein H-NS, indicati

37 ent a mutant of Escherichia coli lacking the histone-like nucleoid structuring protein H-NS.

38 e silencer EAT6 was capable of replacing the histone-like nucleoid structuring protein nucleation fun

39 ncer AT8 is a nucleation site for recruiting histone-like nucleoid structuring protein to form a cis-

40 pression in K pneumoniae was silenced by the histone-like nucleoid structuring protein via direct bin

41 E is repressed by the global regulator H-NS (histone-like nucleoid structuring protein), but can be a

42 onal and architectural profiles of the H-NS (histone-like nucleoid structuring protein)-regulated, os

43 The histone-like nucleoid structuring protein, H-NS, is a pr

44 leoid structuring (H-NS, also referred to as histone-like nucleoid structuring) protein silences tran

45 Members of the histone-like nucleoid-structuring (H-NS) family of prote

46 We recently found that histone-like nucleoid-structuring protein (H-NS) binds t

47 r, foreign DNA appears to be silenced by the histone-like nucleoid-structuring protein (H-NS) in seve

48 Histone-like nucleoid-structuring protein (H-NS) is an a

49 Global colocalization of the histone-like nucleoid-structuring protein (H-NS) with Rh

50 scription of virulence genes silenced by the histone-like nucleoid-structuring protein (H-NS).

51 ssect this mechanism for a model system: the Histone-like Nucleoid-Structuring protein (H-NS).

52 rm into rows [as on binding of the bacterial histone-like nucleoid-structuring protein (H-NS)], large

53 oughout the growth cycle, and shows archaeal histone-like oligomerization behavior.

54 also engineered the sequence of a synthetic "histone-like" peptide to spike into the sample, of which

55 sr2 appears to be a unique protein with both histone-like properties and protective features that may

56 The histone like protein HctA is central to RB:EB differenti

57 In contrast, the histone-like protein (H-NS) and the stationary-phase sig

58 in vitro transcription assay, we showed that histone-like protein (HLP), a homologue of Escherichia c

59 The histone-like protein (HlpA) is highly conserved among st

60 In addition to its role in the nucleoid, the histone-like protein (HlpA) of Streptococcus pyogenes is

61 hether a highly abundant nucleoid-associated histone-like protein (HU) happens to be the glue in ques

62 y includes integration host factor (IHF) and histone-like protein (HU); both are present in the extra

63 tase (SP-STP) and their endogenous substrate histone-like protein (SP-HLP).

64 Consequently, we propose this bifunctional histone-like protein as a candidate that could structura

65 rate an alternative function for an archaeal histone-like protein as a transcriptional regulator, wit

66 PRM2 is a histone-like protein essential to spermatogenesis and wa

67 HU (Histone-like protein from Escherichia coli strain U93) i

68 The effects of HU, the histone-like protein from Escherichia coli, on the equil

69 nomical approach for gene delivery using the histone-like protein from the hyperthermostable eubacter

70 ption from this promoter is repressed by the histone-like protein H-NS and requires OmpR-P for induct

71 s a stable complex with the Escherichia coli histone-like protein H-NS and transfer RNAs (tRNAs).

72 richia coli and to determine the role of the histone-like protein H-NS in this environmental regulati

73 teomic analysis, we found that the bacterial histone-like protein H-NS interacts with Arn, implying a

74 The histone-like protein H-NS is a major component of the ba

75 Here, we report that the histone-like protein H-NS is an aerobic repressor of cyd

76 rotein Csp15, and increased synthesis of the histone-like protein H-NS.

77 by cell extract requires the presence of the histone-like protein H-NS.

78 ly acquired genes, which are silenced by the histone-like protein H-NS.

79 pBA transcription even in the absence of the histone-like protein H-NS.

80 One of the known targets of histone-like protein H1 is flhDC, the master operon whic

81 tilis acetylome and found that the essential histone-like protein HBsu contains seven previously unkn

82 2A, respectively, and to the archaebacterial histone-like protein HMf-2.

83 (E) and O(I), specifically interact with the histone-like protein HU and close the loop in supercoile

84 tion of plectoneme-free regions, whereas the histone-like protein HU and SMC (structural maintenance

85 omarkers that allow such discrimination: the histone-like protein HU form B, the 10 kDa chaperonin Cp

86 The histone-like protein HU from Escherichia coli is involve

87 erved much slower dissociation kinetics of a histone-like protein HU from the whole chromosome during

88 The histone-like protein HU is involved in compaction of the

89 phosphate, a DNA-bending protein such as the histone-like protein HU or integration host factor (IHF)

90 gal operators (OE and OI) and binding of the histone-like protein HU to a specific locus (hbs) about

91 he gal promoters also requires the bacterial histone-like protein HU which acts as a co-factor.

92 a coli requires Gal repressor (GalR) and the histone-like protein HU.

93 may contribute to such processes include the histone-like protein HU.

94 vely supercoiled DNA and the presence of the histone-like protein HU.

95 disclose the in vivo organization of a viral histone-like protein in bacteria.

96 ith high identity to zebrafish H1M, a linker histone-like protein involved in primordial germ cell sp

97 odies to streptolysin O, indicating that the histone-like protein is released by group A streptococci

98 s identified a direct repressor of bfrB, the histone-like protein Lsr2.

99 The gene, termed tcbC, encoded a histone-like protein of 14.5 kDa.

100 ophage 29 protein p6 has been described as a histone-like protein that compacts the viral genome by f

101 Adenovirus encodes the histone-like protein VII, which causes catastrophic glob

102 Integration host factor (IHF) is a bacterial histone-like protein whose primary biological role is to

103 with FliF (the MS ring protein) and H-NS (a histone-like protein).

104 d, the expression of the gene coding for the histone-like protein, hns, was significantly derepressed

105 l nucleoid remodeling dependent on conserved histone-like protein, HU is one of the determining facto

106 Here we present data showing that the histone-like protein, HU, has a role in the molecular pa

107 s flanking the promoters, (2) the binding of histone-like protein, HU, to a site between the GalR-bin

108 two distal operators, and the binding of the histone-like protein, HU, to an architecturally critical

109 Using an altered bacterial histone-like protein, HUalpha, we show that reorganizati

110 those disrupting hns, which encodes a small histone-like protein, resulted in increased eptA transcr

111 activator, and is repressed by YmoA, a small histone-like protein.

112 By contrast, 'histone-like' protein (i.e. Fis, IHF and H-NS) -binding

113 Histone-like proteins (such as HU, H-NS, and Fis) partic

114 gap by investigating 11 types of histone and histone-like proteins across humans, Drosophila, and Arc

115 iption is required in cells deficient in the histone-like proteins Fis or IHF.

116 These structures, organized by histone-like proteins H-NS and StpA, have key roles in r

117 s components of Escherichia coli pre-RC, two histone-like proteins HU and IHF (integration host facto

118 However, the precise function of halophilic histone-like proteins remain unclear.

119 while non-specific binding of IHF and other histone-like proteins serves to structure the nucleoid.

120 cytoplasmic Large DNA Viruses (NCLDV) encode histone-like proteins that in Melbournevirus were shown

121 protein has some features characteristic of histone-like proteins, and we showed that purified HP119

122 The chlamydial histone-like proteins, Hc1 and Hc2, function as global r

123 unlike other structurally related bacterial histone-like proteins, IHF has evolved a sequence-depend

124 gement of kDNA is related to the presence of histone-like proteins, known as KAPs (kinetoplast-associ

125 rt the characterization of a group of linker histone-like proteins, named the GH1-HMGA family in Arab

126 ain DNA-binding proteins, such as histone or histone-like proteins, to modulate topology of chromosom

127 e specific nucleoprotein complexes involving histone-like proteins, which repress promoter activity w

128 paternal genome and replaces sperm-specific histone-like proteins.

129 ed two independent acquisitions of bacterial histone-like proteins.

130 tein of influenza A H3N2 subtype possesses a histone-like sequence (histone mimic) that is used by th

131 ic transcription factor (TF) composed of two histone-like subunits (NF-YB and NF-YC) and a sequence-s

132 results strongly suggest the existence of a histone-like surface on TFIID.

133 This is the first demonstration that a non-histone-like TAF is required for continuous, high level

134 responsible for expression of cTAF(II)31, a histone-like TAF(II) residing in both the transcription

135 Unexpectedly, we find that the histone-like TAF(II)s have distinct roles in expression

136 subunits shared by TFIID and SAGA are three histone-like TAF(II)s, which have been proposed to form

137 It was shown previously that three histone-like TAFs are broadly required for transcription

138 for TAFs in transcription, we find that the histone-like TAFs are generally required for in vivo tra

139 s, indicating its loss of function, like the histone-like TAFs, causes degradation of the constituent

140 ilizing interactions of TAFs, especially the histone-like TAFs, in TFIID.

141 ressed by overexpression of any of the other histone-like TAFs.

142 e of the gene encoding TAF25p, that this non-histone-like TBP-associated factor, which is shared betw