ライフサイエンスコーパス: homeobox protein

1 raction with members of the PBC subfamily of homeobox proteins.

2 or and human diabetes gene pancreas/duodenum homeobox protein 1 (Pdx1) regulates beta-cell survival a

3 e best known of which is pancreatic duodenal homeobox protein 1 (Pdx1).

4 tudy of cardiac function in prospero-related homeobox protein 1 (Prox1) heterozygous mice, using pres

5 ic identity through upregulation of prospero homeobox protein 1 (PROX1), the master regulator of lymp

6 levels of the transcription factor prospero homeobox protein 1 (PROX1), which relieved repression of

7 and the transcription factor paired-related homeobox protein 1 (PRRX1; alias PRX-1), a newly identif

8 type, expressing lymphatic markers (prospero homeobox protein 1 and vascular endothelial growth facto

9 results in attenuated expression of prospero homeobox protein 1 during development.

10 r 3 (VEGFR-3) but not of LYVE-1 and prospero homeobox protein 1.

11 reciprocal downregulation of paired related homeobox protein 1.

12 onan receptor 1]: p < 0.05; PROX-1 [prospero homeobox protein 1]: p < 0.001) compared with control su

13 ing the transcription factor T cell leukemia homeobox protein-1) has a major role in the pathogenesis

14 Caudal-related homeobox protein 2 (Cdx2) is an intestine-specific trans

15 ntaining the K50 class homeodomain Pituitary homeobox protein 2 (PITX2) bound to its consensus DNA si

16 cription factor 3), and Shox2 (short-stature homeobox protein 2), have been identified, the cis-regul

17 r observed that MSEW increased orthodenticle homeobox protein 2, a transcription factor promoting PNN

18 n-positive interneurons, PNNs, orthodenticle homeobox protein 2, and MSEW-induced anxiety and hyperac

19 cine zipper protein (HD-ZIP)-encoding genes: HOMEOBOX PROTEIN 21 (HB21), HOMEOBOX PROTEIN 40 (HB40),

20 encoding polyglycine (polyG) in zinc finger homeobox protein 3 (ZFHX3), also known as AT-binding tra

21 xpression of the transcription factor double homeobox protein 4 (DUX4) can lead to a number of diseas

22 we show that the transcription factor double homeobox protein 4 (DUX4), and its previously characteri

23 ectopic reactivation of the embryonic double homeobox protein 4 gene (DUX4) in skeletal muscle.

24 caused by aberrant expression of the double homeobox protein 4 gene (DUX4) in skeletal muscle.

25 -encoding genes: HOMEOBOX PROTEIN 21 (HB21), HOMEOBOX PROTEIN 40 (HB40), and HOMEOBOX PROTEIN 53 (HB5

26 N 21 (HB21), HOMEOBOX PROTEIN 40 (HB40), and HOMEOBOX PROTEIN 53 (HB53).

27 cgn), specificity protein 8 (SP8) and/or LIM homeobox protein 7 (Lhx7) separates striatal CR+ interne

28 ed null mutations of GSC, encoding Goosecoid homeobox protein, a paired-like homeodomain transcriptio

29 initiation do not express KNOX (Knotted-like homeobox) proteins, a molecular marker for shoot apical

30 t and included LIM1, POD1, GFRA1, WT1, BCL2, Homeobox protein A11, timeless, pleiotrophin, HGF, HNF3,

31 Our previous study of LPS predicted homeobox protein A5 (HOXA5) as a target of miR-26a-2, an

32 ked by the activity-dependent neuroprotector homeobox Protein (ADNP) and located near cell-cycle gene

33 vered that activity-dependent neuroprotector homeobox protein (ADNP) was indispensable for immune rea

34 Here we identify a novel role for UNC-4 homeobox protein and its corepressor UNC-37/Groucho, in

35 e confirm for the first time the presence of homeobox proteins and a frizzled homologue in myxozoan p

36 Because BELL homeobox proteins are a family of plant-specific transcr

37 Homeobox proteins are critical regulators of development

38 Three-amino acid extension loop (TALE) homeobox proteins are highly conserved transcription reg

39 Ato repression is mediated by the conserved homeobox proteins BarH1 and BarH2.

40 ough RNA seq and qPCR analysis we identified homeobox protein, Barx1, as a marker for DPSCs.

41 The homeobox protein Barx2 is expressed in both smooth and s

42 ral retina leucine zipper) and CRX (cone rod homeobox) proteins bind to the adjacent NRE and Ret-4 si

43 er," and motifs in this enhancer contain the homeobox protein-binding site TTATTAACA.

44 Expression of the homeobox protein CDX1 is lost or reduced in a significan

45 Homeobox proteins comprise a major class of transcriptio

46 HOX gene-encoded homeobox proteins control body patterning during embryon

47 Mutations in the cone-rod-homeobox protein CRX are typically associated with domin

48 rid screens with Nr2e3 as bait, the cone-rod homeobox protein Crx was identified as an interacting pa

49 st two-hybrid assays indicated that cone-rod homeobox protein (CRX) interacts with ataxin-7, we perfo

50 ral retina leucine zipper (NRL) and cone-rod homeobox protein (CRX), two rod-specific differentiation

51 The cardiac muscle-restricted homeobox protein Csx/Nkx2.5 (Csx) is expressed in the pr

52 family, NKx 2.5, the cardiac muscle-specific homeobox protein (CSX).

53 Because BLR encodes a BELL1-like (BELL) homeobox protein, direct binding of BLR to AG cis-regula

54 benstein and colleagues demonstrate that the homeobox proteins Dlx1 and Dlx2 promote interneuron migr

55 n the transcriptional regulation mediated by Homeobox proteins during embryonic development and cellu

56 al subtypes express Distalless-related (DLX) homeobox proteins during their differentiation, we set o

57 the 2C-specific transcription factor double homeobox protein (DUX) mediates an essential negative fe

58 the insulinoma-associated protein, IA-1, the homeobox protein Gsh-1, and the vertebrate but not the D

59 e identified the hematopoietically expressed homeobox protein Hhex as a transcription factor regulati

60 up-regulated Ape1 via a transcription factor homeobox protein Hox-A5-dependent mechanism.

61 In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have been associated w

62 -adapted populations in the frequency of the Homeobox protein Hox-C4 (HOXC4) rs190771160 variant, a g

63 NUP98 fused to the homeodomain region of the homeobox protein HOXA9, and acts as an aberrant transcri

64 epigenetic silencing of RASSF1A requires the homeobox protein HOXB3.

65 of KRAS-mutant NSCLCs aberrantly express the homeobox protein HOXC10, largely due to unappreciated de

66 om overexpression of a class 1 KNOTTED1-like homeobox protein in Arabidopsis plants.

67 r findings support a key role for the HOXC10 homeobox protein in cervical cancer progression.

68 d the ability to bind with TaHOX1 (the first homeobox protein in Triticum aestivum).

69 dings suggest that these variants affect the homeobox protein IRX3.

70 suggest that the activity of KN1 and related homeobox proteins is maintained following intercellular

71 We demonstrate that Hopx, an atypical homeobox protein, is a specific marker of +4 cells.

72 Previous studies have shown that the LIM homeobox protein Islet1 (ISL1) marks the LGE subventricu

73 We report here that the intestine-specific homeobox protein ISX is critical to control the metaboli

74 e for beta-catenin-mediated expansion of LIM/homeobox protein Lhx2(+) cells, in the stem/early progen

75 tative NKE elements, possible targets of NK2 homeobox proteins like the essential islet transcription

76 Here we show that homeobox protein Mohawk (Mkx) is a key transcription fac

77 pregulation of the MyoD1 negative regulator, homeobox protein Mohawk, and decreased Wnt signaling.

78 lly cloned cog-1 and found that it encodes a homeobox protein most similar to the mammalian GTX and N

79 rentiation from a primitive and pluripotent (homeobox protein Nanog+/ sex-determining region Y-box 9+

80 protein interaction network surrounding the homeobox protein Nanog.

81 diac MLCK is highly regulated by the cardiac homeobox protein Nkx2-5 in neonatal cardiomyocytes.

82 Decreased levels of the prostate-specific homeobox protein NKX3.1 are correlated with hormone-refr

83 The prostatic homeobox protein Nkx3.1, a known proliferation inhibitor

84 n the nucleus and with an androgen-regulated homeobox protein (NKX3.1) in the cytoplasm of LNCaP cell

85 n vertebrate embryogenesis identified Xom, a homeobox protein of the bone morphogenetic protein 4 pat

86 we identify a pathway in which the conserved homeobox protein Orthodenticle (Otd) acts together with

87 gulation of the expression boundaries of the homeobox proteins Pax6, Dbx2 and Msx1 generates precurso

88 n of five of these proteins as the dispersed homeobox protein PDX-1.

89 Like certain other homeobox proteins, PDX-1 contains a consensus FPWMK moti

90 leading to organ asymmetry - implicating the homeobox protein Pitz-2 in one key step - and others sup

91 The clustered homeobox proteins play crucial roles in development, hem

92 In vertebrates, PBC and MEIS homeobox proteins play important roles in development an

93 ype specific, with transcription factors and homeobox proteins predominating in embryonal cells and g

94 granule cells, coexpressed calbindin and the homeobox protein Prox1.

95 a previously identified gene that encodes a homeobox protein required for normal trichome and root h

96 nes encoding the DM protein kinase (DMPK), a homeobox protein Six5 and a protein containing WD repeat

97 The homeobox protein STF-1 appears to function as a master c

98 ed localization of Not mRNA, which encodes a homeobox protein that distinguishes mesoderm from endode

99 CDX1 is a homeobox protein that inhibits proliferation of intestin

100 , designated GPBOX, encodes a 227-amino-acid homeobox protein that is first expressed at E10.5 in the

101 ions and responses; and (c) HLX1, encoding a homeobox protein that may regulate T-cell development.

102 ; the cold shock protein, CspC; the YbgS (or homeobox protein); the putative stress-response protein

103 ain are the response elements for the NKx2.1 homeobox protein, thyroid transcription factor 1 (TTF1).

104 s that are distinct from, but interact with, homeobox proteins to establish lineage-specific gene exp

105 ) fusions of KN1 and Arabidopsis KN1-related homeobox proteins to that of the viral movement protein

106 LeHB-1, a previously uncharacterized tomato homeobox protein, was shown by gel retardation assay to

107 tina-specific transcription factor, cone-rod homeobox protein, which binds to a pineal regulatory ele

108 investigate the mechanism by which the Six1 homeobox protein, which has a crucial role during develo

109 valuated by immunohistochemistry for CDX2, a homeobox protein whose expression in normal adult tissue

110 opment and function, including LIM proteins, homeobox proteins, wnt and T-box pathway proteins, as we

111 regulated targets, zinc finger E-box binding homeobox proteins ZEB1 and ZEB2, which act as transcript

112 -regulation of the zinc finger E-box binding homeobox protein, ZEB2, and the down-regulation of miR-2