ライフサイエンスコーパス: homing

1 tification using Next Generation Sequencing (HOMINGS).

2 he biosphere in DNA restriction, repair, and homing.

3 cyte chemoattractant protein-1, and monocyte homing.

4 ng genes through a mechanism known as intron homing.

5 which inhibits BM vascular cell adhesion and homing.

6 nt assembly with anionic molecules and tumor homing.

7 ation regarding the efficiency of CAR T-cell homing.

8 hemokine-receptor imprint indicative of skin-homing.

9 CXCR4-dependent manner of hMSC migration and homing.

10 renewal, proliferation, differentiation, and homing.

11 l candidate ChR have been implicated in skin homing.

12 proved porphyrin pharmacokinetics and tumour-homing.

13 G-CSF administration diminished cancer cell homing.

14 senchymal stromal cells (MSC) in cancer cell homing.

15 1 may play an important role in ADSC-TM cell homing.

16 ylation are important for controlling B cell homing.

17 roles in endothelial function and lymphocyte homing.

18 an T-cell beta2AR is critical for T(EM) cell homing.

19 OT-I mice did not exhibit this preferential homing.

20 d expressed markers of exhaustion and tissue homing.

21 f the samples was determined using QIIME and HOMINGS.

22 Despite anecdotal reports of the astonishing homing abilities in dogs, their homing strategies are no

23 ing displaced to distant sites have impaired homing ability but it is unknown what the role of olfact

24 d by their immunogenic nature and poor tumor homing ability, thus oAd cannot be utilized to treat dis

25 provide additional functionalities, such as homing, adhesion or hypoxia resistance.

26 tage over functional, population-suppressing homing alleles.

27 The absence of natal homing allows resistant individuals to spread quickly th

28 a tissue homing signature and the epithelial homing alpha-E integrin (CD103) through transforming gro

29 autoantibody responses by increasing the gut-homing alpha4beta7 integrin expression on Tfh cells.

30 Gut-homing alpha4beta7(high) CD4(+) T lymphocytes have been

31 on induced cell surface expression of T-cell homing and activation proteins, including ICAM-1, VCAM-1

32 cquiring features compatible with lymph node homing and antigen presentation, but unexpectedly expres

33 n-3 (K3)-mediated integrin adhesion controls homing and bone marrow (BM) retention of normal hematopo

34 ruption of retinoid homeostasis affected gut-homing and differentiation of lymphocytes and displayed

35 ation, specifically hampering gut lymphocyte homing and IgA(+) plasma cell differentiation.

36 T) likely contributed to dysregulated T cell homing and impaired lung immunity.

37 ng is a key component of steady-state tissue homing and in mounting an inflammatory response.

38 our results suggest that SOX11 promotes MCL homing and invasion and increases CAM-DR through the dir

39 molecular effects of pFUS increased both MSC homing and MSC production of VEGF and IL-10, suggesting

40 Basal lymphocyte homing and neutrophil recruitment to inflamed sites are

41 ors, linTT1-functionalized NWs showed robust homing and penetration into malignant lesions, whereas o

42 NMR measurements showed greater CAR T cell homing and persistence in the tumors and spleen compared

43 ted by NKTR-214 increases the proliferation, homing and persistence of anti-tumor T cells compared to

44 cally rooted in the need for rapid stem cell homing and proliferation during early development and/or

45 n (CLA(+) ) T cells are specialized for skin homing and represent the main T-cell population in atopi

46 hematopoietic stem cell regulation mediating homing and retention to the niche in the bone marrow.

47 numbers was associated with superior tissue homing and survival abilities and was largely mediated b

48 Sympathetic nerves contribute to the homing and survival of hypertension-specific T(EM) cells

49 xhibit unique signatures supporting roles in homing and survival, with an ability to evade immune sur

50 hotopic model of osteosarcoma revealed tumor homing and systemic immune expansion.

51 is accompanied by Th2/Tc2 activation in skin-homing and systemic subsets, correlating with disease se

52 cytokine polarization among circulating skin-homing and systemic subsets, which differentiates it fro

53 em adhesion molecules involved in lymphocyte homing and the translation of those discoveries into the

54 The mechanisms driving blood cell homing and their interactions with hematopoietic microen

55 cells to express cycling, activation, tissue-homing and tissue residency markers.

56 r findings suggest that IL10 inhibits BM-FPC homing and transdifferentiation to myofibroblasts in pre

57 thod to evaluate cell biodistribution, tumor homing, and fate in preclinical studies.

58 reg cell biology, including their stability, homing, and functional specialization; integrating these

59 umor-targeting peptides for selective tissue homing, and fusogenic lipid coatings to induce fusion wi

60 omoted SDF-1-CXCR4-axis-mediated chemotaxis, homing, and long-term engraftment when these cells were

61 differ in cytokine production, cytotoxicity, homing, and memory traits.

62 r regulation of BCR signaling, Ab responses, homing, and tolerance.

63 an adhesion protein that mediates intestinal homing, and we demonstrated KMT2D-dependent control of I

64 16S community profiles were obtained by HOMINGS, and 408 bacterial species and 84 genus probes w

65 ocal signalling interactions and immune cell homing; and identifies cell types that are directly affe

66 tification Using Next-Generation Sequencing (HOMINGS) approach was used to analyze the microbiomes of

67 e DNA rearrangement steps during WHO element homing are very similar to those during mating-type swit

68 d their expression of several candidate skin-homing-associated chemokine receptors was measured using

69 combinational DNA repair, the probability of homing-associated loss of the effector, the fitness cost

70 ool, heritably maintained a predilection for homing back to their tissue of origin on subsequent reac

71 could readily be adapted to engineer stable, homing-based drives in relevant organisms.

72 n ultrasonic vocalization without changes in homing behavior.

73 Ultrasonic vocalization and homing behavioral experiments were carried out at releva

74 practices and T-cell maturation, intestinal homing (beta7hi), activation, and HIV-1 coreceptor (CCR5

75 The neutrophil-selective homing by MS LECs may retain neutrophils in the LN medul

76 Tissue colonization (homing) by blood-borne cells critically hinges on the ab

77 ges are thus universal "plug-and-play" tumor-homing cancer therapeutics.

78 ying increased cytotoxic markers and altered homing capabilities, and remaining relatively stable ove

79 therapy but is limited by the lack of tumor-homing capability of the current antiangiogenic agents.

80 s and activation of nonspecific T cells with homing capacity to inflamed tissues are associated with

81 by the presence of circulating T cells with homing capacity to inflamed tissues, including the gut m

82 hted repercussions of ECM remodeling on cell homing, cardiac fibroblast activation, and focal adhesio

83 on of Programmed Death-1 (PD-1) and the skin-homing CCL17.

84 ue to the epigenetic regulation of the brain-homing CCR6+ CD4 and CD8 T cells.

85 gulatory T cells and increased CXCR3+ tissue-homing CD4 T cells.

86 Piperacillin-responsive skin-homing CD4(+) clones expressing an array of Vbeta recept

87 ma (CTCL), an often-fatal malignancy of skin-homing CD4(+) T cells for which there are few effective

88 and enzyme-linked immune absorbent spot, gut-homing CD8 T cells, interleukin-2, symptoms, video capsu

89 re, enzyme-linked immune absorbent spot, gut-homing CD8 T cells, intraepithelial leukocyte counts, an

90 T-cell subsets with distinct functional and homing characteristics exist, but the signaling pathways

91 critical for the induction of the key thymus-homing chemokine receptor - CCR6 on Tregs.

92 c acid esters on the expression of the brain-homing chemokine receptor CCR6 in CD4 and CD8 T cells of

93 human CD4+ memory T cells expressing the gut-homing chemokine receptor CCR9 and found a reduced frequ

94 cells expressed higher levels of CCR6, a CNS-homing chemokine receptor, and exhibited a regulatory pr

95 derived clones expressed high levels of skin-homing chemokine receptors and migrated in the presence

96 xpanded Tregs reveal an enhancement in graft-homing chemokine receptors, which may be partly responsi

97 hed from the other clusters as being a "skin-homing chemokines/IL-1R1-dominant" cluster, whereas clus

98 We aimed to compare frequencies of skin homing (CLA(+) ) vs systemic (CLA(-) ) "polar" CD4(+) an

99 sure cytokine production by circulating skin-homing (CLA(+)) versus systemic (CLA(-)) "polar" CD4(+)/

100 usceptibility to HIV-1 infection (CCR5+, gut-homing, CM CD4+ T cells) was preferentially expressed in

101 R1+ and alpha4beta7+ emigration- and mucosal-homing competent phenotype, while this was restricted to

102 We show that this homing CRISPR-Cas9 system acts as an expressed genetic b

103 Peripheral blood skin-homing/cutaneous lymphocyte antigen (CLA)(+) T cells eme

104 T-cell activation, respectively, within skin-homing/cutaneous lymphocyte antigen (CLA)(+) versus syst

105 These results show that a haplolethal homing drive can provide an effective tool for targeted

106 Here, we present a homing drive in Drosophila melanogaster that reduces the

107 rformance closely resembles that of standard homing drives in Drosophila melanogaster.

108 gree of genetic specificity achievable using homing drives, for example based on the CRISPR/Cas9 syst

109 A charge-based cartilage homing drug delivery platform like this can elicit disea

110 n NK cell proliferation and priming for skin-homing during an acute viral infection in humans.

111 nal PET imaging and quantification of T-cell homing during inflammation and cardiomyocyte viability a

112 es (without exogenous supplements), and cell-homing effects on bone-targeting diseases, such as prost

113 effects of MSC therapy by overcoming the low homing efficiency of MSCs systemically administered in i

114 such a 'compass run' significantly increased homing efficiency.

115 Some inteins contain a homing endonuclease (HEN) responsible for their propagat

116 aining an 18-base pair recognition site of a homing endonuclease (I-SceI), which is found by chance o

117 I-PpoI is a homing endonuclease that has a high cleavage activity an

118 extensively retargeted variants of a single homing endonuclease, that have been shown to function ef

119 LAGLIDADG homing endonucleases (LHEs) are a class of rare-cleaving

120 cues caused the animals to make directional homing errors and that the magnitude and direction of th

121 We examined tissue homing, expression of PLZF, T-bet, and RORgammat, and cy

122 rtment, which included an increase in T cell homing factors, erythropoiesis, and adipogenesis.

123 Unlike monocytes or dendritic cells, gut-homing gammadelta T-APCs employed an IL-6 independent me

124 CRISPR-based homing gene drives have sparked both enthusiasm and deep

125 However, CRISPR-based homing gene drives proposed for this purpose have faced

126 enetically related to a family of unorthodox homing genetic elements found in Torulaspora and Lachanc

127 A homing guide RNA (hgRNA) scaffold directs the Cas9-hgRNA

128 Taxonomic profiles were obtained by HOMINGS (Human Oral Microbe Identification using Next Ge

129 re overload enhanced BM-FPC mobilization and homing in IL10KO mice compared with WT mice.

130 n forested areas, and analyzed components of homing in over 600 trials.

131 posed system and its robustness to imperfect homing, incomplete penetrance of toxins and transgene fi

132 including embryonic development, lymphocyte homing, inflammation, and cancer progression.

133 CD4+ T cells expressing the gut homing integrin complex alpha4beta7 are associated with

134 ch acts on T(H) cells to induce IL-5 and gut-homing integrin.

135 nded, differentiated, and imprinted with gut-homing integrins permissive of migration into the damage

136 ng CCR5 co-receptors and alpha4beta7 mucosal homing integrins were decreased.

137 l subset that coexpresses high levels of gut-homing integrins, CD103 and alpha4beta7.

138 e molecular mechanisms regulating lymphocyte homing into lymph nodes are only partly understood.

139 Later stages in T-cell homing involve chemokines (Ch) and lymphocyte chemokine

140 Efficient hematopoietic stem cell (HSC) homing is important for hematopoietic cell transplantati

141 n generated a population of gastrointestinal-homing LAP(+)Foxp3(-) Treg cells.

142 exhibited uniquely low expression of the gut-homing marker alpha4beta7 and were not enriched at the g

143 k 6, whereas cells expressing the intestinal homing marker increased steadily in the central memory (

144 Engineered gene drives based on a homing mechanism could rapidly spread genetic alteration

145 ltiplexin and Eater as an integral part of a homing mechanism that specifies and maintains hematopoie

146 ranscriptional programs controlling cellular homing, metabolism, and potential effector functions.

147 same proportional navigation guidance law as homing missiles.

148 stimulatory molecule CD86 and the lymph node homing molecule CCR7 on S. aureus-infected DCs.

149 racterize their function(s), and examine gut-homing molecule expression in blood and intestinal tissu

150 enotype enriched for chemokine receptors and homing molecules that facilitate migration to sites of i

151 ectins) or a surface (expressing recombinant homing molecules).

152 a monolayer of endothelial cells (expressing homing molecules, e.g., selectins) or a surface (express

153 ssembly with therapeutic cargo, forming HER3-homing nanobiologics.

154 Due to the preferential homing of AnxA5 to the TME enriched with PS+ tumor cells

155 Homing of B cells to Peyer's patches was partially rescu

156 No changes in homeostatic turnover and homing of B cells were detectable, limiting the effects

157 that IL10 inhibits pressure overload-induced homing of BM-FPCs to the heart and their transdifferenti

158 ericytic cell surface markers suppresses the homing of cancer cells to the bone marrow.

159 and lesional CCL17 accounted for the dermal homing of CD8(+)CCR4(+) T-cells, that along with a conco

160 attractant cytokines mediating retention and homing of circulating cells.

161 erm trigger an immune response that promotes homing of circulating leukocytes to the uterine lumen to

162 d follicular stromal cells and modulates the homing of CXCR5-expressing cells toward the FDC-containi

163 Targeted homing of engineered T-cell immunotherapies holds promis

164 Glucocorticoids induced rapid bone marrow homing of eosinophils.

165 orter, PLA2 or 12-Lox activity also inhibits homing of germ cells in vivo Using a live-imaging chemot

166 ermination of lesion growth, cyst formation, homing of GFP(+)/Tie2(+) EPCs, numbers of circulating EP

167 This is not due to reduced homing of Grasp55-deficient cells to these organs but to

168 s provide an architectural basis for nuclear homing of HIV-1 replication complexes and subsequent int

169 eading to defects in adhesion, migration and homing of HSCs regenerated in a Wnt5a-haploinsufficient

170 Homing of HSPCs from bloodstream to bone marrow (BM) is

171 Little is known regarding lymph node (LN)-homing of immune cells via afferent lymphatics.

172 pregulates local chemoattractants to enhance homing of intravenously (IV)-infused MSC and improve out

173 LinTT1-functionalization increased tumor homing of iron oxide nanoworms (NWs) across a panel of f

174 sures to skeletal muscle would improve local homing of iv-infused MSCs and their therapeutic efficacy

175 mental insights into mechanisms that control homing of lymph-derived immune cells.

176 or immune cell subsets, suggestive of active homing of MAIT cells to the site of infection.

177 iated with GR deficiency results in impaired homing of mature B cells to bone marrow, whereas migrati

178 Homing of pathogenic CD4(+) T cells to the CNS is depend

179 establish that RAGE-PR3 interaction mediates homing of prostate cancer cells to the bone marrow.

180 Tfh and B cells, which is essential for the homing of Tfh cells and the development of B cell follic

181 TORC2(DC-/-) and not to enhanced lymph node homing of the cells.

182 emokine receptor, which induces preferential homing of the engineered cells to the small intestine, a

183 t neovessels and a concomitant loss of tumor homing of the nanosystem.

184 explored for the refinement of the cutaneous homing of the therapeutic stem cells.

185 This immunotherapeutic regimen caused homing of tumor-infiltrating DC to draining lymph nodes

186 mokine receptors if possible to increase the homing of vaccine-primed cells to sites of infection.

187 extranodal lymphomas of mature CD4(+), skin-homing or skin-resident T cells.

188 the chemotactic cues along the perivascular homing paths, leading to rapid block of entry.

189 nanosystem consisting of a tumor vasculature-homing peptide (CGKRK) fused to a pro-apoptotic peptide

190 e wall and multiple copies of a breast-tumor-homing peptide at its tip.

191 Since the tumor-homing peptide can be discovered and customized virtuall

192 Silencing of MYOCD in RAL rats by a cardiac homing peptide conjugated MYOCD siRNA resulted in attenu

193 (D)VAP is a tumor homing peptide exhibiting high binding affinity to gluco

194 Nanoparticles directed by the tumor-homing peptide iRGD were selectively taken up by primary

195 Here we describe the homing peptide that interacts with the C-isoform of Tena

196 with an extended C-terminus comprised of CAR homing peptide that recognizes inflamed blood vessels an

197 umors yield a distinct landscape of vascular homing peptides characterized by over-representation of

198 uctural peptides, cell-penetrating and tumor-homing peptides, antimicrobial peptides, peptide hormone

199 Moreover, by incorporating tumor-homing peptides, immunostimulatory nucleotide-bearing na

200 mor-specific affinity ligands, such as tumor homing peptides.

201 Homing performance improves continuously over generation

202 focused-ultrasound (pFUS) increases enhanced homing permeability and retention of MSC in mouse kidney

203 and warrant strict safety monitoring of gut-homing perturbing agents used in treating intestinal inf

204 Homing phenotypes of circulating lymphocytes were analyz

205 e, we compared the flight characteristics of homing pigeons (Columba livia) flying solo and in pairs

206 Here, we use homing pigeons to investigate whether the repeated remov

207 or, CD44, on MSC membranes, to improve their homing potential towards an inflammatory site without af

208 ine production, gene expression, plasticity, homing potentials, and their reactivity to self-antigens

209 new germline niches as they develop and this homing process is directed by a Sphigosine-1-Phosphate (

210 tron-encoded endonucleases that initiate the homing process.

211 PARC inhibited in vivo and adipocyte-induced homing, proliferation, and invasion of OvCa cells.

212 We have therefore examined the BM homing properties of human induced pluripotent stem cell

213 follicles by ectopic expression of the CXCR5 homing protein.

214 results support the engineered expression of homing proteins to direct CD8 T cells to target tissues

215 s) are multiplexed, increasing the effective homing rate and decreasing the effective resistant allel

216 the vector, and then use the nuclease-based homing reaction as a form of gene drive to spread those

217 of different molecular processes during the homing reaction, various fitness effects, and the effica

218 ubset of RORgammat(+) ILC2s express the skin-homing receptor CCR10, and the frequencies of IL-17-prod

219 Expression of the gut homing receptor CCR9 on T-effector memory cells 30 days

220 cells also express the vascular endothelium-homing receptor CX3CR1 and migrate toward CX3CL1-express

221 We first demonstrated that the primary homing receptor for linTT1, p32 (or gC1qR), is expressed

222 eptor and was also recently found as a novel homing receptor for T-cells implicated in colitis.

223 Here, engineered expression of the CCR9 homing receptor redirected CD8 T cells to the small inte

224 BW preterm neonates, their expression of the homing receptors alpha4beta7, CCR4, and CCR9 was altered

225 t varied in expression of CD7; CD10; and the homing receptors CCR7, CCR9, and ITGB7.

226 1 activity led to enhanced expression of the homing receptors CD62L and CCR7.

227 ouse model of OS abundantly express the skin homing receptors cutaneous lymphocyte associated antigen

228 sis, ILCP in PB of mouse and human expressed homing receptors for secondary lymphoid organs, mainly C

229 ion and expression of transcription factors, homing receptors, and signaling molecules appear to play

230 alphaalpha cells and their expression of gut-homing receptors.

231 s MBC subsets that have profoundly different homing, residency, and functional properties, and mediat

232 matical model to estimate tolerable rates of homing-resistant allele generation to suppress a wild po

233 uppressed populations rapidly rebounding, as homing-resistant alleles have a significant fitness adva

234 with current designs, the slow emergence of homing-resistant alleles is expected to result in suppre

235 7 and alpha4beta1, critical for gut and lung homing, respectively.

236 R3(+), CD103(+,) CD49a(+), CD69(+), CD127(+) homing, retention and survival markers.

237 ting memory CD8 T cell pool expressing liver-homing/retention markers (CD69(+)CD103(+) CXCR6(+)CXCR3(

238 paired individuals benefitted from improved homing route accuracy, which reduced flight distance by

239 Homing routes are more similar in consecutive generation

240 lls had gestationally regulated responses to homing signals and/or adhesion mechanisms that influence

241 cytes and increased expression of lymphocyte-homing signals in the metastatic tumors.

242 to prime CD8(+) T cells expressing a tissue homing signature and the epithelial homing alpha-E integ

243 ese bystander T cells express defined tissue homing signatures that suggest their recruitment to infl

244 4beta7 integrin expression and imprinted gut-homing specificity on T cells.

245 astonishing homing abilities in dogs, their homing strategies are not fully understood.

246 a novel genetic amplified nanoparticle tumor-homing strategy to enhance the MRI accuracy of ultrasmal

247 icotinoid pesticide, thiamethoxam, decreases homing success in honey bees.

248 Macrophage homing/survival signals were determined at 14 days after

249 To remedy this, we theoretically explore a homing system architecture in which guide RNAs (gRNAs) a

250 he recent development of a CRISPR-Cas9-based homing system for the suppression of Anopheles gambiae i

251 ed for current designs for CRISPR-Cas9-based homing systems.

252 n incurable non-Hodgkin lymphoma of the skin-homing T cell.

253 ood and skin phenotypes and determining skin-homing T-cell functional properties are needed to establ

254 tment to the gut, while impairing Th17 cells homing through the CCR6-CCL20 axis in treated HIV-1-infe

255 ified pathological cardiac ECM prevents cell homing, thus providing further hints to identify a possi

256 in atherosclerosis and the process of T cell homing to atherosclerotic plaques.

257 Memory T cell homing to BM during DR was associated with enhanced prot

258 a phenotype associated with effective B cell homing to but not within lymph nodes.

259 eby enhancing both CAR T-cell activation and homing to CXCL9/10-expressing tumours to eradicate HER-2

260 or type 5, a chemokine receptor required for homing to GCs) and expand in lymph nodes (LNs) following

261 cell release and may promote progenitor cell homing to ischemic calf muscle.

262 ity parameters in vivo but showed comparable homing to lymphoid organs and intact in vitro migration

263 (VEGF) and interleukin-10 (IL-10) than MSCs homing to non-pFUS-treated muscle.

264 n vitro selection of DNA aptamers capable of homing to nuclei of cultured cells without transfection

265 cells from the gut, suggesting that they are homing to or from the gut.

266 can be engineered to become capable of first homing to orthotopic breast tumors and then capturing an

267 Furthermore, MSCs homing to pFUS-treated CLI muscle expressed more vascula

268 7 cells are completely dependent on CCR6 for homing to psoriasiform skin.

269 events engraftment syndrome and allows their homing to secondary lymphoid organs for promoting tolera

270 allows for expression of CXCR3 and efficient homing to sites of T(H)1 responses.

271 from degradation and clearance; 2) selective homing to target cell types; and 3) cytoplasmic release

272 CXCR3-mediated TNF(+) T cell homing to the BM upregulated the Th17 chemoattractant CC

273 dard transplantation protocol relies on cell homing to the bone marrow after intravenous injection.

274 f MSC pharmacologically enhanced cancer cell homing to the bone marrow in mice.

275 s-endothelial migration of HSPCs since their homing to the bone marrow vasculatures remained intact.

276 distributed within peripheral organs without homing to the brain.

277 (DF) induces GCX degradation, leading to CTC homing to the endothelium, a first step in secondary tum

278 e progression and proper autoreactive T-cell homing to the epidermis.

279 IL-7R blockade reduced human T cell homing to the gut and colonic inflammation in vivo in hu

280 duced mucosal injury, and reduced lymphocyte homing to the gut.

281 ic humoral and cellular responses and induce homing to the intestinal and female genital mucosae.

282 (MAdCAM-1) to selectively reduce lymphocyte homing to the intestinal tract.

283 ve immune responses, including CD4(+) T-cell homing to the intestine and the development of IgA-produ

284 pment of the cells in the lungs, followed by homing to the liver and to a joint afflicted with hemart

285 e, or defects of T cell activation or T cell homing to the site of inoculation.

286 We discuss the mechanisms of eosinophil homing to the TME and examine their diverse pro-tumorige

287 c stem and progenitor cells (HSPCs) involves homing to the vasculatures and lodgment to their niches.

288 abine followed by EBV-CTLs results in T-cell homing to tumors and inhibition of tumor growth.

289 in multiple tumour types and role in cancer "homing" to bone marrow.

290 , their seasonal timing and possible return (homing) to western headwater tributaries where they were

291 cipate that coupling DO sequences with tumor-homing transduction domains can create a potentially val

292 Skin-homing Treg cells also play a critical role in mitigatin

293 ory T cells, and induced preferential T-cell homing via modulation of vascular endothelial cells.

294 use model, we demonstrate generation of lung-homing, virus-specific T effectors after influenza infec

295 In subgroups, leukocyte homing was blocked by integrin antibodies (n = 5).

296 Such exposure may impair foraging and homing, which are vital to normal colony function and ec

297 cells was sufficient to promote bone marrow homing within a short timeframe.

298 emokine that supports B-cell trafficking and homing within the bone marrow, a major CD53 function ide

299 pidermis, colonising the skin and eventually homing within the hair follicles.

300 y contrast, integrins are dispensable for LN homing, yet still contribute by increasing the dwell tim