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1 iana NFU1 assembles one [4Fe-4S] cluster per homodimer.
2 identified as ligands for the CD8alphaalpha homodimer.
3 PiSFI3 forms an unusual trans-homodimer.
4 ld type, and that there are two active sites/homodimer.
5 mediated through production of the IL-12p40 homodimer.
6 is functionally equivalent to the mouse MafA homodimer.
7 for many years that LPL was only active as a homodimer.
8 lly on the metabotropic glutamate receptor 2 homodimer.
9 eric Cdc10 drives assembly of the core Cdc10 homodimer.
10 monomer interacts with a monomer of the Cmu1 homodimer.
11 d adjacent to the C-terminal regions of each homodimer.
12 o comprehensively characterize the hole-hole homodimer.
13 nd 2-fold higher than the Ser(838)-harboring homodimer.
14 QC division depends on formation of the SHR homodimer.
15 ed for the stability and function of the TM2 homodimer.
16 microtubules over micrometer distances as a homodimer.
17 riptional program and DNA-damage repair as a homodimer.
18 BD2) bound to an RNA duplex as an asymmetric homodimer.
19 oloenzyme is a tetramer that consists of two homodimers.
20 ytoplasm, while none of these mutants formed homodimers.
21 no acid residue for the formation of HLA-B27 homodimers.
22 nic phospholipids, regulating activated PDK1 homodimers.
23 homodimers fourfold compared to constitutive homodimers.
24 lotypes (HLA-B*27:02 to HLA-B*27:09) to form homodimers.
25 ively formed antiparallel L18W-PGLa and MG2a homodimers.
26 d reduction in the lateral mobility of ErbB3 homodimers.
27 icans and Candida parapsilosis formed stable homodimers.
28 family of galectins and bridging potency of homodimers.
29 tudy the asymmetric function of melanocortin homodimers.
30 ient cells, MNT binds to MLX, but also forms homodimers.
31 ponsible for its compromised ability to form homodimers.
32 ponsible for its compromised ability to form homodimers.
33 -4 heterodimers being more stable than ClC-4 homodimers.
34 g heterodimers with bHLH TFs or from forming homodimers.
35 otility on single microtubules as individual homodimers.
36 s) that are typically thought to function as homodimers.
37 of this protein, and the tetherin TMD forms homodimers.
38 sine 7 upon engagement by antibodies or KACL homodimers.
39 , followed by the assembly of inactive Pol I homodimers.
40 a transcriptional coregulator of p52 and p50 homodimers.
41 ow that Pnc1 co-import requires Gpd1 to form homodimers.
42 purify without contaminating GDF9 and BMP15 homodimers.
43 ers of BTB proteins while sparing functional homodimers.
44 2DeltaEx16) that forms constitutively active homodimers.
45 g affinity for NRXNs or its capacity to form homodimers.
46 nductance compared with the TRESK and TREK-2 homodimers.
47 nels are assembled as primitive antiparallel homodimers.
48 y rates of the KIF3AA and much slower KIF3CC homodimers.
49 chemical and motile properties as engineered homodimers.
52 chical equations of motion approach on model homodimers, a method used in the intermediate coupling r
53 ate T cells via an anti-CD3 (aCD3) arm, aCD3 homodimer (aCD3 HD) and high-molecular-weight species (H
54 ution within the hCCS interface reduces hCCS homodimer affinity, creating a pool of hCCS available to
55 nal dynamics of the two subunits forming the homodimer and allosteric perturbations on cGMP binding.
56 ent transcription factor, FgSR, that forms a homodimer and binds to a 16-bp cis-element of its target
57 emonstrated with holo glutaredoxin 5 (GLRX5) homodimer and holo GLRX5:BolA-like protein 3 (BOLA3) het
60 es as a switch to boost the activity of MDM2 homodimer and promote its self-destruction to enable rap
61 '3'-cGAMP induces closing of the human STING homodimer and release of the STING C-terminal tail, whic
62 ng of the spike trimer to more than one ACE2 homodimer and suggests a mechanical contribution of the
64 his mutation eliminates the function of BMP7 homodimers and all other BMPs that normally heterodimeri
65 inetics of KIF3A and KIF3C when expressed as homodimers and analyzed in vitro are distinctively diffe
66 pting BRAF-containing dimers, including BRAF homodimers and BRAF-CRAF heterodimers, but not CRAF homo
68 rbB3 and ErbB2 led to the formation of ErbB3 homodimers and ErbB3/ErbB2 heterodimers in a competitive
69 ia, the fastest variants discovered here are homodimers and exhibit a much simpler folding and activa
70 tematically the thermodynamic stabilities of homodimers and heterodimers of kainate and AMPA receptor
73 h other GPCRs; however, the existence of APJ homodimers and oligomers remains to be investigated.
74 found that PiT1 and PiT2 form high-abundance homodimers and Pi-regulated low-abundance heterodimers.
75 enhancement of viral infectivity require Nef homodimers and support a mechanism by which the Nef dime
77 disease-associated HLA-B27 allotypes to form homodimers and the failure of HLA-B*27:03 to form homodi
78 used to determine the affinity of parental (homodimer) and bispecific (heterodimer) interactions wit
79 rofile change was observed for the hole-hole homodimer, and the multiple HIC peaks were explored and
80 tion of HER2 through disruption of HER2-HER2 homodimers, and (ii) the subsequent degradation of HER2
81 characteristics of KIF3C when expressed as a homodimer are exceeding slow, whereas homodimeric KIF3AA
84 s, suggesting that RAF heterodimers, and not homodimers, are the major players in determining the amp
85 he insertion of one [4Fe-4S](2+) cluster per homodimer as determined by UV-visible absorption/CD, res
86 FtsZ-binding pocket, which defines the SepF homodimer as the functional unit, and suggests a reversi
88 The two beta-subunits make a tightly bound homodimer at the center, and two alpha-subunits are boun
89 ssays, we show that both Lu and Lu(v13) form homodimers at the cell surface of epithelial cancer cell
99 wo different multidrug ABC transporters, the homodimer BmrA from Bacillus subtilis and the heterodime
103 mmetric surface pockets present on the PNPOx homodimer, but this site has never been verified by othe
105 Following stimulation by ATP, the NLRP6 homodimer can further assemble into a linear molecular p
107 imers and the failure of HLA-B*27:03 to form homodimers challenge the role of HLA-B27 homodimers in A
109 owed a significantly reduced ability to form homodimers compared with all other allotypes, including
110 study of the full-length protein, revealed a homodimer comprising a coiled coil with two independent
111 xibility translates into an ensemble of ACE2 homodimer conformations that could sterically accommodat
113 photosynthetic cytochrome b (6) f complex, a homodimer containing eight distinct subunits and 26 tran
114 ion of drug candidates, with minimal risk of homodimer contamination using a single Protein A chromat
117 hat the DNA-binding preferences of AR and GR homodimers differ significantly, both within and outside
119 in absence of PRO and incapable of forming a homodimer due to a steric clash of an ENZ-specific tyros
120 a small fraction was present as constitutive homodimers exhibiting a ~40% lower mobility than monomer
122 oteins: FemX adds the first glycine, and the homodimers FemA and FemB sequentially add two Gly-Gly di
123 molecule located at the center of the PD-L1 homodimer, filling a deep hydrophobic channel-like pocke
125 oop in the carboxyl terminus of LPL prevents homodimer formation and forces LPL into a monomeric stat
127 ), and Phe(121)) and demonstrated attenuated homodimer formation in a cell-based fluorescence complem
132 tational method for the modeling of parallel homodimers formed by transmembrane (TM) alpha-helices.
134 B3 significantly and reduced the mobility of homodimers fourfold compared to constitutive homodimers.
135 suggest piston-type TM signaling by the TM2 homodimer from PASP across the full TM region, whereas t
137 cles is experimentally revealed by comparing homodimer H-bond energies of aromatic heterocycles with
138 ating desired bispecific molecules, parental homodimers, half molecules, and antibodies with mispaire
139 72, Thr76, Gly80' and Tyr83') forms a stable homodimer, has catalytic activity similar to the wild ty
140 sid proteins (from four heterodimers and two homodimers) have obvious structural homology while seque
142 5D2-bound LPL monomers are as stable as LPL homodimers (i.e., they are not more prone to unfolding),
144 MPE is a monomer, whereas Mre11 and SbcD are homodimers; (ii) MPE lacks the capping domain present in
148 owever, sensitive detection of low-abundance homodimer impurities can still be challenging for regula
152 electrophoresis revealed that CAR can form a homodimer in a configuration in which the PP2A/RACK1 bin
153 a 3.7 angstrom cryo-EM structure of the KimA homodimer in an inward-occluded, trans-inhibited conform
154 stance of the membrane and forms a stable TM homodimer in both the inactive and fumarate-activated st
155 hic studies demonstrated that RABL3 formed a homodimer in solution via interactions between the effec
158 revealing that full-length CYP102A1 forms a homodimer in which both the heme and FAD domains contact
161 BMP7/BMP4 heterodimers are more active than homodimers in vitro, but it is not known whether these h
164 at the cross-linking time of alpha-actinin-4 homodimers increases approximately twofold within the ce
166 l structure of the EMC that consists of Erh1 homodimers interacting with Mmi1 in a 2:2 stoichiometry
169 ese ANGPTLs inactivate LPL by converting LPL homodimers into monomers, rendering them highly suscepti
171 domain)/IR(intracellular-domain) demonstrate homodimer IRalpha enhances insulin binding and signaling
174 Cryo-EM revealed that the Delta12 variant homodimer is conformationally more stable and incapable
175 usively on CD8(+) T cells, the CD8alphaalpha homodimer is present in subsets of T cells and human nat
176 we show that overexpression of a forced E2A homodimer is sufficient to drive robust neural commitmen
179 es that HLA-B27 heavy chains aberrantly form homodimers, is a central hypothesis that attempts to exp
180 single-molecule velocities of the engineered homodimers KIF3AA and KIF3CC are 293 and 7.5 nm/s, respe
181 eq and gene-editing we show that the p50/p50 homodimer known to act as repressor for a number of pro-
182 Treating larvae and adults with r-bursicon homodimers led to up-regulation of five anti-microbial p
187 in speeds similar to KIF3AC, suggesting the homodimers mechanically impact each other's motility to
193 eterodimer that corresponds to the canonical homodimer observed in all previously reported PRMTs.
194 loop, T-cell receptor binding, formation of homodimer of alpha-beta heterodimers, and cholesterol bi
195 meric association, consisting of a disc-like homodimer of CNNM2BAT bound to two independent PRL-1 mol
196 9- angstrom resolution, depicting a parallel homodimer of protocadherin-15 EC1-3 molecules forming an
199 s formed from anti-electrostatic anion-anion homodimers of organophosphates and cyanostar macrocycles
200 We have previously shown evidence of stable homodimers of SERCA2a in heterologous cells and cardiomy
201 sed heterodimer stability as compared to the homodimers of their constituents, matching well physiolo
203 A binding specificity by forming cooperative homodimers on precisely spaced and oriented DNA sites.
205 nd structural results indicate that the EutD homodimer opens the pyrimidine ring of ectoine through a
206 action of Omomyc is to bind DNA as either a homodimer or a heterodimer with Max that is formed cotra
214 on of human IgG, creating a fully functional homodimer (or "lysibody") with high-affinity binding and
215 two conserved binding modes: forming C2A/C2A homodimers, or forming a heterodimer with the zinc finge
220 vation that only a single subunit of the p66 homodimer precursor is susceptible to HIV-1 protease.
224 subunit of the periplasmic domain of the Tsr homodimer (pTsr) has an intact serine-binding site.
228 ligand binding domain (LBD) of the mGluR7/7 homodimer revealed it to have an apparent affinity ~4000
229 DNA interactomes of 80 heterodimers and 22 homodimers revealed that 72% of heterodimer motifs corre
230 zation of receptor complexes, including Ror2 homodimers, Ror2/Fzd7 and Ror2/dsh heterodimers in an en
231 crystal revealed a typical four-helix bundle homodimer, similar to previously well-studied chemorecep
232 ys revealed that Gsx2 binds both monomer and homodimer sites in the developing mouse ventral telencep
234 rse homo-oligomers in solution, and 15 (four homodimers, six homotrimers, six homotetramers and one h
235 the versatility of this method in separating homodimer species from bsAb based on either electrostati
236 (>=95%) by inducing partial disorder in one homodimer species without affecting the heterodimer.
238 rinsic tryptophan for UV-B perception with a homodimer structure containing 26 structural tryptophan
239 rmacophore designed to target a melanocortin homodimer such that one receptor is occupied by an agoni
240 cted between RTA and the non-truncated P2-P2 homodimer, suggesting that the structural architecture o
241 e prodomain in the pro- and latent myostatin homodimers, suggesting a 1:1 (antibody:myostatin homodim
243 ation of a more symmetrically arranged PD-L1 homodimer than that previously reported for other inhibi
244 unique 3(10)-helical feature present in MDM2 homodimer that allows pS429 to stabilize the closed E2-u
245 ering, and electron microscopy unveil an XPG homodimer that binds, unstacks, and sculpts duplex DNA a
249 ere, we produce stable recombinant E protein homodimers that are recognized by strongly neutralizing
250 tor allosteric signaling that occurs between homodimers that can be applied straightforwardly in vitr
251 sequence homology and form disulphide-linked homodimers that contain a pair of acidic aspartic acid r
253 y characterized bacterial beta-etherases are homodimers that fall into two distinct GST subclasses: L
254 ve form of E. coli Ia RNR is composed of two homodimers that form the active alpha(2)beta(2) complex.
255 peroxide H(2) Both COX isoforms are sequence homodimers that function as conformational heterodimers
256 tudies show that each bursicon subunit forms homodimers that induce prophylactic immunity in Drosophi
259 estigate heterodimerization among known GPCR homodimers: the CXC chemokine receptor 4 and sphingosine
264 he Escherichia coli chorismate mutase (EcCM) homodimer to be dependent on incorporation of a noncanon
265 Fascetto (Feo) in Drosophila, which forms a homodimer to cross-link interzonal MTs, ensuring proper
266 se findings, we test a model showing how the homodimer to monomer site ratio and the Gsx protein leve
268 CAR undergoes a conversion from inactive homodimers to active heterodimers with retinoid X recept
273 matted into scalable bsAbs that were free of homodimer traces by combining interface exchange, asymme
275 inity, which places the DNA residence of the homodimers under thermodynamic rather than kinetic contr
276 ious studies have established that the Hsp90 homodimer undergoes an ATP-driven cycle through open and
277 e spatial domain organization within the p66 homodimer using pulsed Q-band double electron-electron r
280 a/beta constant domain pair and the IgG1 CH3 homodimer was evidenced by X-ray crystallography and use
281 S-box TF usually works by forming hetero- or homodimers, we conducted yeast-two-hybrid screening and
282 because ATF4 is unable to form highly-stable homodimers, we hypothesized that ATF4 may promote muscle
284 GAFb) and a catalytic domain, cone PDE6 is a homodimer whereas rod PDE6 consists of two homologous ca
285 pharmacological profile similar to the TRESK homodimer, whereas the presence of the TREK-2 subunit re
286 main' RXLR effector that forms a novel trans-homodimer which is required for its ability to suppress
287 ull-length OsCYP20-2 promotes OsFSD2 forming homodimers which enhance its activity, eliminating the a
288 describe the structure of a PcdhgammaB7 cis-homodimer, which includes the membrane-proximal extracel
290 erodimers are 10 times more stable than IAPP homodimers, which explains the substoichiometric ability
291 demonstrating that the CC3 forms a parallel homodimer whose dimer interface is formed by a small num
294 ein from methane-oxidizing bacteria, forms a homodimer with a dicopper Cu(A) center at the dimer inte
297 the modern tetramer evolved-a noncooperative homodimer with high oxygen affinity that existed before
299 a subset of kinesin-14 motors that exist as homodimers with an N-terminal microtubule-binding tail,
300 the leptospiral PerR revealed an asymmetric homodimer, with one monomer displaying complete regulato