ライフサイエンスコーパス: homodimeric

1 Cytoplasmic dynein is a homodimeric AAA+ motor that transports a multitude of ca

2 In a homodimeric ABC exporter such as MsbA responsible for li

3 r feature differentiating heterodimeric from homodimeric ABC exporters.

4 as a new parameter in the mechanism of this homodimeric ABC transporter.

5 he p140 catalytic subunit (POLG) and the p55 homodimeric accessory subunit (POLG2), which enhances bi

6 le catalytic subunit, encoded by Polg, and a homodimeric accessory subunit encoded by the Polg2 gene.

7 (2) POLG2 encodes the approximately 110-kDa homodimeric accessory subunit, p55.

8 ukaryotic nonmuscle cells, regulation of the homodimeric actin cross-linking protein alpha-actinin-4

9 The homodimeric adhesion/growth-regulatory galectin-1 and a

10 ds on our recently reported structure of the homodimeric alpha-crystallin domain (ACD) and C-terminal

11 agonist ([(3)H]UNSW-MK259, [(3)H]19) and its homodimeric analogue [(3)H]UR-AP060 ([(3)H]33).

12 are believed to have evolved from an extinct homodimeric ancestor through a process of gene duplicati

13 ty and observed that GrxD can form FeS-bound homodimeric and BolA containing heterodimeric complexes.

14 PtaA is homodimeric and contains a pyridoxal phosphate cofactor.

15 The protein is homodimeric and contains a uniquely ligated two iron-two

16 ellular roles of GrxD as a component of both homodimeric and heterodimeric complexes to ultimately un

17 h factor-beta (TGF-beta) family of secreted, homodimeric and heterodimeric proteins controls the diff

18 B, p50, and p52, which assemble into several homodimeric and heterodimeric species.

19 Importantly, mutations induced by both homodimeric and heterodimeric TALENs are passed efficien

20 iological significance of human lectins with homodimeric and tandem-repeat-type displays.

21 The H chain of these homodimeric antibodies consists of one antigen-binding d

22 ee amino acid insertion into the middle of a homodimeric archaeal histone fold motif.

23 The enzyme displays a multidomain, homodimeric architecture and footprints a DNA region of

24 these channels in the TMEM16 family share a homodimeric architecture facilitated by their cytoplasmi

25 Human TMEM175 adopts a homodimeric architecture with a central ion-conduction p

26 tor tyrosine kinases with a disulfide-linked homodimeric architecture.

27 Modeling of the homodimeric ASC PYD complex formed via an asymmetric int

28 enables structural asymmetry of the overall homodimeric assembly and allows signal transduction to t

29 meso-diaminopimelate decarboxylase adopts a homodimeric assembly.

30 ylase) complex, could adopt a salt-dependent homodimeric association with its target epigenomic loci.

31 We also report the structure of the homodimeric Atg7 C-terminal domain, which is homologous

32 structure of ATM kinase, which is an intact homodimeric ATM/Tel1 from Schizosaccharomyces pombe.

33 cassette sub-family G member 2 (ABCG2) is a homodimeric ATP-binding cassette (ABC) transporter that

34 d-facing crystal structures of the bacterial homodimeric ATP-binding cassette transporters MsbA from

35 Hsp90 is a homodimeric ATP-dependent molecular chaperone that remod

36 Hsp90 is a homodimeric ATPase that is essential in eukaryotes for t

37 membrane-spanning heterodimer, MalF-MalG; a homodimeric ATPase, MalK2; and a periplasmic maltose rec

38 The homodimeric bacterial enzyme, undecaprenyl diphosphate s

39 cence resonance energy transfer (FRET), that homodimeric bacterial SSB from Thermus thermophilus (Tth

40 y can be applied to the engineering of other homodimeric bacteriophytochromes, which will further exp

41 xB), which we have termed mod2B, composed of homodimeric beta subunits that contain amino acid sequen

42 nomic data to accurately infer monomeric and homodimeric binding motifs.

43 ure of the BEN-DNA target complex, revealing homodimeric binding of the BEN domain and extensive nucl

44 Finally, hepcidin and Id1 mRNA induction by homodimeric BMP2, homodimeric BMP6, and heterodimeric BM

45 and Id1 mRNA induction by homodimeric BMP2, homodimeric BMP6, and heterodimeric BMP2/6 were blunted

46 e molecules allows the direct observation of homodimeric boronic acids and their heterodimeric comple

47 d Flamingo), an atypical cadherin that forms homodimeric bridges between adjacent cells.

48 As a consequence, homodimeric but not monomeric p85alpha suppresses the PI

49 ans contains genes for two SSB homologs: the homodimeric, canonical Ssb, encoded by the gene ssb, and

50 Moreover, ligands that disrupted the homodimeric CAR interactions in its D1 domains triggered

51 he dimer-dimer interaction interface between homodimeric CC MBS and homodimeric LZ PKG-Ialpha.

52 , we report the 3D NMR solution structure of homodimeric CC MBS in which amino acids 932-967 form a c

53 c simulations, we study various sequences of homodimeric CC, in both parallel and antiparallel config

54 nature of the low-pH structural form of the homodimeric CcdB (controller of cell death B) protein.

55 rystal structures of IgV domains that form a homodimeric CEACAM6 complex, monomeric CEACAM8, and a he

56 we characterize Clr-a as a disulfide-linked homodimeric cell surface glycoprotein.

57 ons, recent studies have indicated that this homodimeric chaperone can also assume a variety of asymm

58 et of type III secretion (TTS) autoinhibited homodimeric chaperones adopt a molten globule-like state

59 genes and clarify the function of kif17, the homodimeric ciliary kinesin gene.

60 ded by the kif3c-like (kif3cl) gene, and the homodimeric ciliary kinesin, kif17, are dispensable for

61 Comparison of NgBR/DHDDS with homodimeric cis-PTase structures leads to a model where

62 rization yielded a mechanistic blueprint for homodimeric class I cytokine receptor activation and its

63 Homodimeric class I cytokine receptors are assumed to ex

64 issect the action at the pathway entrance in homodimeric Clostridium tetani H(+)-PPase upon ligand bi

65 he bivalent carbohydrate-binding property of homodimeric CNL is essential for its activity, providing

66 -terminal domain, revealing a 15-nm parallel homodimeric coiled coil.

67 t to design a set of orthogonal antiparallel homodimeric coiled coils using a computational approach.

68 gineer sets of three orthogonal antiparallel homodimeric coiled coils.

69 C2A releases UNC-13L from an autoinhibitory homodimeric complex to become fusion-competent by functi

70 PSAJ: complex crystal structure suggested a homodimeric complex with considerably fewer sequence-spe

71 with benzodiazepine binding across the CCK1R homodimeric complex, resulting in their ability to inhib

72 logous metazoan dynein light chains, forming homodimeric composite substrate binding sites that engag

73 omistic representations of each receptor, in homodimeric configurations with either transmembrane hel

74 ons suggest that the mutations stabilize the homodimeric conformation, positioning the cytosolic kina

75 viously been crystalized in a characteristic homodimeric conformation.

76 h motor domain was characterized by studying homodimeric constructs, and a global fit to the data res

77 These domains are tethered to the homodimeric Core by ~30-residue linkers that are suscept

78 protein functions in the same pathway as its homodimeric counterparts (mitoNEET and NAF-1), and could

79 ct asymmetrical backbone motions, unlike its homodimeric counterparts that face the cytosolic side of

80 and have better toxicity profiles than their homodimeric counterparts.

81 Analysis of the homodimeric CrISA1 structure reveals a unique elongated

82 Additionally, we reveal that homodimeric CTD can bind carotenoid in the absence of NT

83 ion (seconds) and slow decay (hours) of this homodimeric Cu(A) site to two mononuclear Cu(2+) sites,

84 Interleukin-5 is a Th2 homodimeric cytokine involved in the differentiation, ma

85 he extracellular membrane proximal domain of homodimeric cytokine receptors as a key regulator of int

86 prolactin receptor as an archetype model of homodimeric cytokine receptors to address the role of th

87 d that JAK2-V617F requires interactions with homodimeric cytokine receptors to elicit its transformin

88 the interleukin-17 family form six different homodimeric cytokines (IL-17A-F) and the heterodimeric I

89 Legionella pneumophila uses a single homodimeric disulfide bond (DSB) oxidoreductase DsbA2 to

90 The core NHEJ machinery comprises the homodimeric DNA end-binding protein Ku and DNA ligase D

91 t a mode of interaction where the N-terminal homodimeric domain of Rtt106 intercalates between the tw

92 nd in vitro, and mutations in the N-terminal homodimeric domain of Rtt106 that affect formation of Rt

93 w that the editing endonucleases do not form homodimeric domains, and may therefore function as inter

94 pplicable to a large range of complexes with homodimeric E1 components.

95 Atg7 is a noncanonical, homodimeric E1 enzyme that interacts with the noncanonic

96 f an E1p-E2p didomain subcomplex involving a homodimeric E1p, and the results may be applicable to a

97 s of Hsc/p70-Interacting Protein (CHIP) is a homodimeric E3 ubiquitin ligase.

98 Our Escherichia coli RNAPsigma(70-)homodimeric EcSspA structure suggests this is a general

99 The heme cavity of the homodimeric enzyme is similar to prokaryotic KatGs inclu

100 hymidylate synthase from Escherichia coli, a homodimeric enzyme known to be half-the-sites reactive.

101 reductase (ccNiR) is a periplasmic, decaheme homodimeric enzyme that catalyzes the six-electron reduc

102 cterize a singly ligated state ("lig1") of a homodimeric enzyme that is otherwise obscured by rapid e

103 LiLPPS is a homodimeric enzyme with a sigmoidal saturation curve and

104 es along the reaction pathway of a bacterial homodimeric enzyme, fluoroacetate dehalogenase (FAcD).

105 med with half-of-the-sites reactivity in the homodimeric enzyme.

106 ture and dynamics facilitates catalysis in a homodimeric enzyme.

107 tified in the Sphingomonadaceae as a soluble homodimeric enzyme.

108 I topoisomerases are essential ATP-dependent homodimeric enzymes required for transcription, replicat

109 These homodimeric enzymes were highly specific for NADPH (Km =

110 Many bacteriophytochromes function as homodimeric enzymes, in which light-induced conformation

111 topoisomerases (Top2alpha and Top2beta) are homodimeric enzymes; they are essential for altering DNA

112 hepsin cascade that is initiated through the homodimeric EPOR complex and is required for the surviva

113 tability and oligomerization dynamics of the homodimeric Escherichia coli beta and the homotrimeric S

114 The four-helix HAMP bundle of the homodimeric Escherichia coli serine chemoreceptor (Tsr)

115 sisting of the import receptor Mia40 and the homodimeric FAD-dependent thiol oxidase ALR.

116 g, resulting in one F(ab')2 molecule and one homodimeric Fc fragment.

117 nprecedented asymmetric structure within the homodimeric Fc polypeptide, enable completely selective

118 cenone atropodiastereomeric pairs, including homodimeric flavomannin A (1) and the previously unrepor

119 unctionally important state as a symmetrical homodimeric form of SecR decorated by monomeric Atr1a, i

120 In contrast, the homodimeric forms of NFkappaB, p50p50 and p65p65, bind D

121 is-PTases have evolved from their ancestral, homodimeric forms to fulfill their function in long-chai

122 binding of the proteins in their hetero- and homodimeric forms.

123 Expression of ErbB2 elevated the homodimeric fraction of ErbB3 even in unstimulated cells

124 HRG stimulation increased the homodimeric fraction of ErbB3 significantly and reduced

125 n microscopy structures of heterodimeric and homodimeric full-length GABA(B) receptors.

126 Using the example of homodimeric galectin-1 and monomeric galectin-3, the mut

127 itio the known high-resolution structures of homodimeric GASright motifs at near-atomic level.

128 (Single-GATA) while a monomeric GATA1 and a homodimeric GATA1 bivalently bind to two GATA motifs in

129 receptor interfaces are formed compared with homodimeric GDF9 and BMP15.

130 While there has been growing interest in the homodimeric gene products of CISD1 (mitoNEET) and CISD2

131 richia coli cAMP receptor protein, CRP, is a homodimeric global transcription activator that employs

132 Stanniocalcin-1 (STC1) is a disulfide-bound homodimeric glycoprotein, first identified as a hypocalc

133 MPO is a homodimeric glycoprotein, posttranslationally modified w

134 fore likely be restricted to closely related homodimeric GPCRs.

135 ization is reversible in vivo, restoring the homodimeric ground state.

136 monomeric hCMG complex and suggest that the homodimeric hCtf4 acts as a platform linking polymerase

137 strate that the hCtf4-CMG complex contains a homodimeric hCtf4 and a monomeric hCMG complex and sugge

138 munoglobulin new antigen receptor (IgNAR), a homodimeric heavy chain-only antibody, as a major part o

139 A homodimeric helical bundle was reconnected into a monome

140 as the symmetry of the starting scaffold, a homodimeric helical protein (DSD).

141 resent a comprehensive geometric analysis of homodimeric helices that demonstrates the existence of a

142 We apply this strategy to the homodimeric hemoglobin HbI from Scapharca inaequivalvis.

143 tin interactions are established through the homodimeric hinge domain of Smchd1 and, intriguingly, th

144 Our demonstration that homodimeric human PrpF39 directly interacts with U1C-CTD

145 ocrystal structure of derivative 31 with the homodimeric human S1P lyase.

146 closely related, internally deleted, SVs of homodimeric human tyrosyl-tRNA synthetase (TyrRS).

147 Here we report crystal structures of homodimeric IL-17A and its complex with IL-17RA.

148 It blocked homodimeric IL-17A with an IC50 value of 21 pm, which co

149 Whereas homodimeric IL-22Ralpha1 SyCyRs failed to activate signa

150 We find that T. maritima FliG(N) is homodimeric in the absence of the FliF(C) peptide but fo

151 A subset of homodimeric interactions could not be modeled on the nuc

152 ral and quantitative differences between the homodimeric interactions of the three mouse PERIOD homol

153 This study identified sites of in vivo homodimeric interactions within ExbD periplasmic domain

154 w that heterodimerization appears to disrupt homodimeric interactions, suggesting the sharing of inte

155 e, as well as the molecular link between the homodimeric interface and TRD loop, leading to enhanced

156 e interplay of target recognition domain and homodimeric interface fine-tunes the distinct target sel

157 Packing defects at the homodimeric interface stimulate binding, whereas correct

158 882H mutation reduces the DNA binding at the homodimeric interface, as well as the molecular link bet

159 ly important regions of TNSALP (active site, homodimeric interface, crown domain, calcium site, ...).

160 the P2 subdomain was mainly involved in the homodimeric interface, whereas a large gap between the P

161 vided by allosteric modulation across a GPCR homodimeric interface.

162 dicated considerable differences between the homodimeric interfaces of AUX/IAA and ARF PB1 domains.

163 ansition and exchanges partners in localized homodimeric interfaces to form an ExbD(2)-TonB heterotri

164 Homodimeric KIF17 and heterotrimeric KIF3AB are processi

165 ly motors--heterotrimeric kinesin-II and the homodimeric Kif17 kinesin--in zebrafish cilia.

166 motor proteins; however, the function of the homodimeric Kif17 motor in cilia is poorly understood, w

167 s significantly slower than ADP release from homodimeric KIF3AA and KIF3BB, which reach 80-90 s(-1) T

168 Heterodimeric KIF3AC and homodimeric KIF3AA and KIF3CC are processive, although t

169 -state kinetics of KIF3AC to the kinetics of homodimeric KIF3AA and KIF3CC.

170 Heterodimeric KIF3AC and homodimeric KIF3AA displayed a similar likelihood of swi

171 d as a homodimer are exceeding slow, whereas homodimeric KIF3AA, as well as KIF3AC, have much faster

172 h ADP release at 78 s(-1) are fast steps for homodimeric KIF3AA.

173 Overall our results implicate homodimeric KIF3CC as a unique promoter of microtubule c

174 microtubule dynamics in vitro, an engineered homodimeric KIF3CC was incorporated into a dynamic micro

175 unctional differences, the heterodimeric and homodimeric kinesin-14s share a common evolutionary stru

176 In Caenorhabditis elegans, homodimeric [kinesin family (KIF) 17, osmotic avoidance

177 tructures of aglycosylated heterodimeric and homodimeric "knob" and "hole" Fc fragments derived from

178 CNL is a homodimeric lectin, each of whose monomers consist of a

179 The cross-linking capacity of homodimeric lectins was enhanced by covalent connection

180 Among them, the homodimeric Ly49 NK receptors, which can adopt two disti

181 ion interface between homodimeric CC MBS and homodimeric LZ PKG-Ialpha.

182 haea In contrast to all flavodoxins, FldA is homodimeric, markedly less acidic, and stabilizes an ani

183 We demonstrate that HbI functions like a homodimeric mechanical device, such as pliers or scissor

184 Survivin, a homodimeric member of the Inhibitor of Apoptosis Protein

185 NAF-1 is a homodimeric member of the novel Fe-S protein NEET family

186 Endophilin A1 is a homodimeric membrane-binding endocytic accessory protein

187 arsenic repressor (ArsR) family of bacterial homodimeric metal-sensing proteins and has emerged as a

188 Moreover, this homodimeric metalloenzyme has been directly linked to bo

189 Copper/zinc superoxide dismutase (SOD) is a homodimeric metalloenzyme that has been extensively stud

190 complex molybdenum cofactor (Moco)-dependent homodimeric metalloenzyme that is vitally important for

191 itis elegans CPS-6, a homolog of EndoG, is a homodimeric Mg(2+)-dependent nuclease, binding preferent

192 Cytoplasmic dynein is a homodimeric microtubule (MT) motor protein responsible f

193 r and central nervous system function - form homodimeric, modular PDZ protein complexes with cell-typ

194 Human fatty acid synthase (hFAS) is a homodimeric multidomain enzyme that catalyzes a series o

195 NOSs are homodimeric multidomain enzymes responsible for producin

196 an meprin beta is a 145-kDa disulfide-linked homodimeric multidomain type-I membrane metallopeptidase

197 es throughout the catalytic cycle of LmrA, a homodimeric multidrug ABC transporter from L. lactis.

198 Escherichia coli EmrE, a homodimeric multidrug antiporter, has been suggested to

199 In our studies on the homodimeric multidrug/lipid A ABC exporter MsbA from Esc

200 The exchange of subunits between homodimeric mutant Cu, Zn superoxide dismutase (SOD1) an

201 ix containing the R1500P mutation folds into homodimeric (mutant/mutant) and heterodimeric [mutant/wi

202 Each ~75-kDa subunit of homodimeric Na(+)-PPase forms an unusual funnel-like str

203 gene duplication and fusion from a classical homodimeric nitroreductase such that the monomeric prote

204 different from the arrangements observed in homodimeric non-NMDA receptors and reveals the molecular

205 The homodimeric NR harbors three cofactors, each of which is

206 radical cofactor, Mn(III)(2)-Y(*), in their homodimeric NrdF (beta2) subunit to initiate reduction o

207 reening strategies to therapeutically target homodimeric oncogenic proteins considered undruggable.

208 e of Fsq, solved to 2.7 angstrom, revealed a homodimeric organization with FAD bound noncovalently.

209 To date, studies have demonstrated that homodimeric p55 disease variants are deficient in the ab

210 c18 plasmids encode parS sites and two small homodimeric ParA-like (delta2) and ParB-like (omega2) pr

211 we report the biochemical properties of the homodimeric PFO of C. reinhardtii expressed in Escherich

212 Homodimeric Plk4 has been shown to be ubiquitinated as a

213 nt a room-temperature neutron structure of a homodimeric PLP-dependent enzyme, aspartate aminotransfe

214 of KIF3AB is tuned somewhat differently from homodimeric processive kinesins.

215 he processivity of KIF3AB in comparison with homodimeric processive kinesins.

216 Human mitoNEET is a homodimeric protein anchored to the outer mitochondrial

217 n this study, we used 14-3-3sigma as a model homodimeric protein and performed a systematic investiga

218 e C-terminal domains of both subunits of the homodimeric protein bind different ends of the intron RN

219 of WT and 14 mutated CRPs to determine how a homodimeric protein can distinguish nonpalindromic DNA s

220 interprotein disulfide formation within this homodimeric protein complex.

221 H(+)-Pyrophosphatase is a membrane-embedded homodimeric protein containing a single type of polypept

222 alysis of CYT-18 shows that both CTDs of the homodimeric protein extend outward from the catalytic do

223 tures (residues 37-61 in each monomer of the homodimeric protein molecule) was systematically varied.

224 Synechocystis sp. PCC6803 is combined in the homodimeric protein of Nostoc sp. PCC7120.

225 TGF-beta1 is a disulfide-bonded homodimeric protein produced by platelets and other cell

226 at shock protein Hsp31 is a stress-inducible homodimeric protein that is involved in diauxic shift re

227 These studies have shown that Hsp90 is a homodimeric protein that requires ATP hydrolysis and a h

228 lecules that could disrupt the constitutive, homodimeric protein-protein interface within CK2beta.

229 It is believed that they arose once from a homodimeric protein.

230 Aldehyde oxidases (AOXs) are homodimeric proteins belonging to the xanthine oxidase f

231 otic CLC anion channels and transporters are homodimeric proteins composed of multiple alpha-helical

232 ymmetry in the absence of ligands in several homodimeric proteins that are either asymmetric function

233 Homodimeric proteins that behave as allosterically modul

234 In contrast to nearly all homodimeric proteins, CHIP is asymmetric.

235 CLC anion channels are homodimeric proteins.

236 Homodimeric proton-translocating pyrophosphatase (H(+)-P

237 se (TR) is a selenocysteine (Sec)-containing homodimeric pyridine nucleotide oxidoreductase which cat

238 The three-dimensional structure revealed a homodimeric quaternary organization, never reported befo

239 and Mossbauer spectroscopic features of the homodimeric QueE point to the presence of a single [4Fe-

240 aerobic chlorophototroph that has a type-I, homodimeric reaction center (RC).

241 2-angstrom resolution x-ray structure of the homodimeric reaction center-photosystem from the phototr

242 s a and c as principal pigments, and type-1, homodimeric reaction centres.

243 roliferative leukemia virus oncogene, MPL, a homodimeric receptor activated by thrombopoietin (THPO),

244 e receptors, identified a functional IL-10R2 homodimeric receptor complex, and uncovered broad recept

245 odimerization results from the divergence of homodimeric receptors and will therefore likely be restr

246 solution crystal structures of reconstructed homodimeric receptors in complex with hen-egg white lyso

247 me assays, we found that rather than HMGL46, homodimeric recombinant HMGL35 is the active enzyme cata

248 These results suggest that the homodimeric RNA complex formed by the SARS pseudoknot oc

249 Functional relevance of a homodimeric S. aureus PI-PLC crystal structure is suppor

250 ructures of bacterial STING define a minimal homodimeric scaffold that selectively responds to cyclic

251 Upon receipt of a stimulus, a homodimeric sensor histidine kinase autophosphorylates a

252 The periplasmic moiety of the homodimeric sensor kinase BvgS is composed of four bilob

253 apicomplexan orthologue to be a functional, homodimeric serine palmitoyltransferase localized to the

254 e enzyme bound with NAD(+) and UDP reveals a homodimeric short-chain dehydrogenase/reductase (SDR), b

255 eta1, -beta2, and -beta3, are small secreted homodimeric signaling proteins with essential roles in r

256 both exist as monomeric, heterodimeric, and homodimeric species throughout the cell cycle.

257 vious observations on homotetrameric SSBs to homodimeric SSBs, indicating that the dynamic features m

258 Homodimeric StaL can accommodate GPA substrate in only o

259 The inactive, homodimeric state absorbs UV-B light, resulting in disso

260 size that WipA can thereby transition from a homodimeric state to a heterodimeric state in which the

261 -angle X-ray scattering, we show that in the homodimeric state, the OH transitions between these two

262 peroxidase (bCcP) enzymes are described by a homodimeric state.

263 substrate, we found that each monomer of the homodimeric structure bound AdoMet in its active site.

264 e binding two zinc ions, the domain adopts a homodimeric structure highly similar to those of a numbe

265 This study is the first to demonstrate the homodimeric structure of 5-HT2C receptors endogenously e

266 The homodimeric structure of CDK2AP1 includes an intrinsical

267 We examine the homodimeric structure of the dominant beta-ladder segmen

268 The homodimeric structure was shown to be dispensible, with

269 The latter exhibits a thioredoxin fold and a homodimeric structure with two intermolecular disulfide

270 The four independent subunits from the two homodimeric structures differ only slightly in the pepti

271 Here, we reveal homodimeric structures of NEGR1 and NTM.

272 r, each crystal structure produced different homodimeric structures, suggesting flexibility in their

273 on was caused by charge reduction using PTR, homodimeric superoxide dismutase/CuZn (31.4 kDa) was sub

274 Here, we constructed homodimeric TALENs to 10 different targets in various en

275 sted symmetric binding modes relative to the homodimeric target; however, none can fully explain SAR

276 studies in S. pneumoniae that an unannotated homodimeric TetR from S. agalactiae (PDB 3KKC) is the bo

277 the glycophorin A (GpA) model system, whose homodimeric TM helix interface has been characterized by

278 eption, UVR8 switches instantaneously from a homodimeric to monomeric configuration, which leads to i

279 e report the development of a broad-spectrum homodimeric tobramycin adjuvant that is nontoxic and mor

280 n a reengineered single-chain version of the homodimeric transcription factor cAMP receptor protein.

281 Peroxide stress regulators (PerRs) are homodimeric transcriptional repressors with each monomer

282 transferrin (hTF) molecules to the specific homodimeric transferrin receptor (TFR) on the cell surfa

283 complex, biologically important system: the homodimeric transmembrane dimer from the alpha chain of

284 selectin glycoprotein ligand-1 (PSGL-1) is a homodimeric transmembrane mucin on leukocytes.

285 Only one DARPin binds to the homodimeric transporter in the absence as well as in the

286 These sets are identical in homodimeric transporters, and remain evolutionary relate

287 e of bound ethidium, revealing an asymmetric homodimeric two-domain molecule with an entirely helical

288 JAK2ex13InDel does not require an exogenous homodimeric type 1 cytokine receptor to transform Ba/F3

289 eeds to directly associate with a functional homodimeric type I cytokine receptor, suggesting that, a

290 NKR-P1B is a homodimeric type II transmembrane C-type lectinlike rece

291 Making it unique among homodimeric type-I RCs, the isolated RC was photoactive

292 or facilitating MORF4L1 self-assembly into a homodimeric unit.

293 , purified to homogeneity, and shown to be a homodimeric uridine phosphorylase, with similar specific

294 photon reception by the Arabidopsis thaliana homodimeric UV RESISTANCE LOCUS8 (UVR8) photoreceptor le

295 UV-B absorption by homodimeric UVR8 induces monomerization and hence signal

296 We reveal that the homodimeric XPF is able to bind various ssDNA sequences

297 ere found in the CD247 gene that encodes the homodimeric zeta protein.

298 east-based assay with activity on par with a homodimeric Zif268 zinc-finger nuclease.

299 IX (CA IX) is an extracellular transmembrane homodimeric zinc metalloenzyme that has been validated a

300 Factor XI (fXI) is a homodimeric zymogen that is converted to a protease with