コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
5 icant differences in DNA methylation between homologous alleles associated with local changes in gene
6 ion of haematopoietic cells to replace their homologous (allelic) counterparts, increasing polygenic
7 the supremely rapid activation of the highly homologous alpha-amino-3-hydroxy-5-methyl-4-isoxazolepro
10 ntigens elicited antibodies that neutralized homologous and heterologous HCV genotypes, blocked the i
11 is organism, and that the relative levels of homologous and non-homologous repair in a given fungal s
12 ase has the potential to distinguish between homologous and nonhomologous RNA templates during sexual
14 noted to be primed for apoptosis with Bcl-2 homologous antagonist/killer activation in vitro and in
15 ations, or in vivo, where contributions from homologous antenna complexes cannot be disentangled.
16 e properties of LEM2 described here, and the homologous architectures of related inner nuclear membra
17 and conformational equilibrium of the highly homologous arrestin-2 and arrestin-3 and found that thes
18 of a Pmt1-Pmt2 structure and comparison with homologous beta-trefoil - carbohydrate complexes allows
19 GABA(B1) and GABA(B2), that are structurally homologous but perform distinct and complementary functi
20 ry insects demonstrates how neurons that are homologous can nonetheless mediate different computation
22 t allows tamoxifen-induced expression of the homologous Card14(E138A) mutation from the endogenous mo
23 A and SidE ubiquitin ligases harbor a highly homologous catalytic phosphodiesterase (PDE) domain.
25 hereas functionally downstream dimorphic but homologous cell types, called male-specific aggression-p
26 bability of developing parasitemia following homologous challenge (p<0.05); v) non-protected subjects
28 plex (SC), a protein structure that mediates homologous chromosomal pairing and class I crossovers.
29 Strikingly, in the absence of the distal homologous chromosome arm dnTA is further increased, wit
35 engineered degradation of Atg14 and observed homologous chromosome segregation followed by sister chr
36 ous end-joining, even in haploid cells where homologous chromosomes are not present during much of th
37 ter-chromosomal interaction patterns between homologous chromosomes are similar, and the similarity i
38 effects could underlie interactions between homologous chromosomes as required for gametogenesis.
40 a meiosis-specific structure formed between homologous chromosomes during prophase that promotes DSB
42 segregation is enabled by crossovers between homologous chromosomes in the first meiotic division.
43 In meiosis, crossover (CO) formation between homologous chromosomes is essential for faithful segrega
45 he 3D nucleus revealed that distances of the homologous chromosomes to the center of nucleus are almo
47 bination and correct segregation of multiple homologous chromosomes, which can form complex multivale
51 Vaccine) and protective efficacy assessed by homologous controlled human malaria infection (CHMI).
57 ture than that predicted from the docking of homologous crystal structures of the separate transmembr
58 revealed a similarly localized rhythm in the homologous deep posteromedial cortex that was temporally
59 ted in behavioural adaptation and control, a homologous definition across mammals is available - but
60 ng the existing literature, we show that the homologous definition better aligns results of rodent st
61 We show that five Formica species exhibit homologous divergent haplotypes spanning 11 Mbp on chrom
63 een shown to be important for RAD51-mediated homologous DNA pairing and HR-mediated DNA repair, the r
64 rface of the S1-S4 voltage-sensor segment of homologous Domain 4, whose movement is associated with i
65 ulating inactive conformations of the highly homologous dopamine D(2) and D(3) receptors (D(2)R and D
68 se (DNA-PK) plays a critical role in the non-homologous end joining (NHEJ) repair pathway and the DNA
70 and breaks are repaired predominantly by non-homologous end joining (NHEJ), which directly ligates DN
72 ights into LINP1's ability to facilitate non-homologous end joining (NHEJ). We characterized LINP1 st
73 choice of homologous recombination over non-homologous end joining and potentially other mutagenic p
75 by repair through either the error-prone non-homologous end joining or the homology directed repair p
79 tween high-fidelity (HF) and error-prone non-homologous end-joining (NHEJ), as well as between proxim
81 . dermatitidis through disruption of the non-homologous end-joining pathway, with three individual ev
83 plied our structural knowledge of DabA and a homologous enzyme from the kainic acid biosynthetic path
84 evolved from ferulic acid esterases, and two homologous enzymes are shown to exhibit MHET turnover.
86 CaM, CaMKII and FGF/fibroblast growth factor homologous factor interactions affect the timing or func
92 rom different metagenomes, we show a pool of homologous gene variants co-exist for each module in eac
94 y predicted by transferring annotations from homologous genes or proteins for which experimental evid
95 ion of numerous flexible gene modules, where homologous genes present in the pan-genome interchange t
96 ent (i.e., CELLULOSE SYNTHASE1) and expansin homologous genes were all down-regulated, indicating the
101 sed binding-site identification, followed by homologous GPCR detections through structure and orthost
102 -reactivity towards allergens from the birch homologous group has been observed in basic research and
103 representative allergen of the Fagales tree homologous group, but further diagnostics may be needed
106 ; (c) new models beyond the current model of homologous groups; (d) simplification of pharmacovigilan
107 he INTU/FUZ heterodimer as a novel member of homologous HerMon (Hermansky-Pudlak syndrome and MON1-CC
109 at when expressed in human cells, two highly homologous HSP70s, HSPA1A and HSPA1L, have opposing effe
111 RRS specificity in competition studies using homologous (inactivated Pitman Moore rabies virus) and h
113 target enzyme and selectivity toward highly homologous isoenzymes, representative examples of the se
116 anced when both sens alleles were present in homologous loci such that each allele was regulated in t
117 s with known and novel CIFs suggest that the homologous LRR-RKs GSO1/SGN3 and GSO2 have evolved uniqu
118 ange rates and analyses of mAb reactivity to homologous LTPs revealed three structural epitopes: two
120 The unc-7 touch defect can be rescued by the homologous mouse gene Panx1 gene, thus, innexin/pannexin
122 nature" by creating a mouse line bearing the homologous mutation in IL-17F (Ser65Leu) by CRISPR/Cas9.
124 ts, suggesting that this approach identifies homologous neurobiological circuits across individuals.
125 ghts, we call for widespread adoption of the homologous nomenclature, and reinterpretation of previou
126 ding leaves, and reverse genetic analyses of homologous NS1 target genes in Arabidopsis, reveal that
127 alignments of 72 chloroplast genes and 7621 homologous nuclear-encoded proteins, for 157 and 76 taxa
131 ior wt-HAI antibody responses against 5 of 6 homologous or drifted strains evaluated compared to unad
135 s-Alder proficiencies (>80% accuracy) of two homologous Pd(2)L(4) metallocages with a variety of subs
136 recognized Amb a-derived T-cell epitopes and homologous peptides from western ragweed (Amb p), giant
138 yclopropanation and competing TFE/c-C(3)F(6)/homologous perfluoroanion generation, (13)C/(2)H KIEs, L
139 ith chloroquine induces protection against a homologous Plasmodium falciparum sporozoite (PfSPZ) chal
140 ally lacked cross-neutralization to a highly homologous pre-emergent bat coronavirus, WIV1-CoV, which
141 ous degrees of functional divergence between homologous primate cytomegalovirus immunevasins and sugg
144 core component of the WASP-family verprolin homologous protein (WAVE) regulatory complex (WRC), as a
145 regulation of CCAAT/enhancer-binding protein homologous protein and immunoglobulin heavy chain bindin
147 vation of the CCAAT-enhancer-binding protein homologous protein, and activation of the cyclic adenosi
148 rotocol was tested on a large set of 285 non-homologous proteins and generated structural models with
149 clustering method that ensures there are no homologous proteins between sets yet maintains the maxim
150 ecially in cases for which no structures for homologous proteins have been experimentally determined(
151 (MFN2) is one of two ubiquitously expressed homologous proteins in eukaryote cells, playing a critic
152 MDFI) and MDFI domain-containing (MDFIC) are homologous proteins known to regulate myogenic transcrip
153 The Akt family is comprised of three unique homologous proteins with isoform-specific effects, but i
154 inase substrate (IRAG, Mrvi1, and Jaw1L) are homologous proteins with small ER luminal domains and la
157 d the modulated targeting vectors to produce homologous recombinant mice directly by pronuclear injec
159 plays a critical role in the choice between homologous recombination (HR) and non-homologous end-joi
160 elomeres, which is associated with increased Homologous Recombination (HR) and TERRA transcription.
161 m BRCA1 germline mutations are deficient for homologous recombination (HR) DNA repair and are sensiti
162 ly, we have shown that NUCKS1 helps maintain homologous recombination (HR) DNA repair in human cells
164 find that Ino80 is selectively required for homologous recombination (HR) DNA repair, which is mecha
165 ss and enhances therapeutic efficacy against homologous recombination (HR) DNA repair-deficient HGSOC
166 trategies that can target BRCA wild-type and homologous recombination (HR) DNA repair-proficient canc
168 s to introduce genome editing reagents and a homologous recombination (HR) donor template into embryo
169 es to stalled replication forks and recruits homologous recombination (HR) factors such as CtBP inter
171 eagues underscores that DNA damage repair by homologous recombination (HR) is not an all-or-nothing p
173 of BRCA-deficient cancer and that defects in homologous recombination (HR) or fork protection (FP) do
175 inaccessible to 53BP1 but permissive to the homologous recombination (HR) proteins RNF169, RAD51, an
177 (DDC) is often robustly activated during the homologous recombination (HR) repair of DNA double stran
178 be restarted and repaired by RAD51-mediated homologous recombination (HR), but HR can also perform p
180 mbination of cisplatin and Nutlin-3 inhibits homologous recombination (HR), which leads to persistenc
182 tic (s)BRCA1/2 mutations or g/s mutations in homologous recombination (HR)-related genes other than B
188 y an important role in transcription-coupled homologous recombination and DNA replication restart.
189 e diverse ways that HPV oncogenes manipulate homologous recombination and ideas on how the resulting
190 ch may be crucial for CtIP functions in both homologous recombination and microhomology-mediated end-
191 ation and the recruitment of proteins of the homologous recombination and non-homologous end joining
192 dishevelled2 gene using CRISPR/Cas9-induced homologous recombination and observed its dynamics direc
193 otes DNA double-strand break (DSB) repair by homologous recombination and protects DNA replication fo
195 ications were likely mediated by non-allelic homologous recombination at regions of high sequence ide
198 yndrome (22q11.2DS) results from non-allelic homologous recombination between low-copy repeats termed
199 otein 1 (RAD51AP1) plays an integral role in homologous recombination by activating RAD51 recombinase
201 patients with BRCA mutations, patients with homologous recombination deficiencies, and the intention
202 lish that ALC1 loss is synthetic lethal with homologous recombination deficiency (HRD), which we attr
203 tion rates were associated with APOBEC3B and homologous recombination deficiency, increasing neoantig
205 9.37 months [95% CI, 6.65 to 11.85 months]); homologous recombination deficient (HRD) cohort (236 ruc
206 s LSTs are a primary functional component of homologous recombination deficient cellular phenotypes,
208 mutational signature 3 reflecting defective homologous recombination DNA repair, and positive immune
211 tion to several additional genes involved in homologous recombination may also have predictive value
212 light on how BRCA1 influences the choice of homologous recombination over non-homologous end joining
213 utations affecting genes associated with the homologous recombination pathway may be underrepresented
215 s it seemed that HPV oncogenes activated the homologous recombination pathway to facilitate the HPV l
217 CHK1i-induced DNA damage by attenuating DNA homologous recombination repair activity and RAD51 foci
218 ock size of six with stratification based on homologous recombination repair gene mutation status, pr
222 Unlike previous in planta or intra-genomic homologous recombination reports in which the original c
224 sation episodes through real-time intra-host homologous recombination while the rest are co-transmitt
226 vergence in relation to their involvement in homologous recombination, exemplifying a duplicate reten
227 ex evolutionary history, including extensive homologous recombination, gene loss, gene duplications,
230 mmonly upregulated in cancers, especially in homologous recombination-deficient cancers, which displa
233 y, the increase of base substitutions in the homologous recombination-deficient Rad51 mutant, specifi
242 ype or COBRA HA antigens were exchanged with homologous regions in the COBRA HA proteins to determine
243 which is stabilized by base pairing between homologous regions of the ASOs bound by each dimer of PC
244 ctural variants, especially in repetitive or homologous regions, can be problematic due to uneven rea
245 ative of major plant lineages, combined with homologous relationships among genes of 72 species from
247 at the relative levels of homologous and non-homologous repair in a given fungal species may play a m
249 flammatory cytokines were also suppressed by homologous RV, as was intestinal damage in response to e
252 of most eutherian mammals share only a small homologous segment, the pseudoautosomal region (PAR), in
254 e of yeast cyclophilin CPR1 by replacing its homologous sequence resulted in a hybrid molecule with s
256 events involving relatively short (<200 bp) homologous sequences, where RecA-mediated recombination
258 utilizing database matching, mass defect and homologous series evaluation, and MS/MS fragmentation ex
262 een for isomeric contributions and to follow homologous series or compound classes, instead of indivi
263 a the relative odds of previous detection of homologous strains (defined by field-inversion gel elect
267 cal structure biasing terms, the addition of homologous template and co-evolutionary restraints to AW
268 protein structure or high sequence identity homologous templates, the approach successfully identifi
269 t1(R455H), a cytoplasmic C-terminal mutation homologous to a human R474H variant that results in EIMF
270 owever, silencing of DvABCB2 which is highly homologous to DvABCB1 at the amino acid level, did not r
271 hose distinguishing features are a catalytic homologous to E6AP C terminus (HECT) domain and 3 centra
273 ntify a family of over 30 enzymes, which are homologous to mammalian carboxylesterase (CES) enzymes,
274 alkane-oxidizing archaea (ANKA) use enzymes homologous to MCR named alkyl-coenzyme M reductase (ACR)
276 vanadium and iron-only nitrogenases that are homologous to molybdenum nitrogenases are also found in
277 cestor already possessed multicopy sequences homologous to most human and chimpanzee palindromes.
278 E1 and PHOTOSYSTEM II PHOSPHATASE, which are homologous to proteins that antagonize the state transit
280 When the host silences these TEs, siRNAs homologous to the captured regions may also target the g
281 , we describe seven vegetative phage genomes homologous to the historic phage B3 that infect Pseudomo
282 BX7 transcript variant 1 (mCbx7v1), which is homologous to the human CBX7 gene (hCBX7v1) and is expre
283 aracterized Drosophila gene CG8108, which is homologous to the human gene CIZ1, as essential for surv
284 that acetylates triacylinositols, a function homologous to the last step in the acylsucrose biosynthe
285 irected silencing via induction of a pathway homologous to the mammalian RIG-I helicase viral respons
286 use the intermicrovillar adhesion complex is homologous to the myosin-7a (MYO7A)-based Usher syndrome
287 lacoderms have traditionally been considered homologous to the palatal vomer-dermopalatine series of
288 lular domain (ECD) of SEMA6A/6B via a region homologous to the receptor-binding site in Clostridioide
289 lastid envelopes of E. gracilis by machinery homologous to the translocons of outer and inner chlorop
291 omere protein A and discovered that they are homologous to viral protein sequences from the Mimivirid
292 mid in control cells by using the endogenous homologous transcript as a template, indicating ATXN3's
295 between the global structural similarity of homologous transporters and the enormous diversity of th
296 nd spectroscopic studies confirm assembly of homologous U(VI)(mu-O(Ar))(2)M(n+) cores with a range of
297 ation-inhibiting (HI) antibodies against the homologous vaccine antigen, most of them also had lower
299 ocerebral segment and are therefore serially homologous with the first appendage pair of extant euart