ライフサイエンスコーパス: homologous gene

1 ded by the RPE65 gene rather than by another homologous gene.

2 me segment and has been proposed to affect a homologous gene.

3 bacteria and red algae possess just one nblA-homologous gene.

4 ve been discovered by chance or by searching homologous genes.

5 c as a result of the disparate regulation of homologous genes.

6 complicated by the functional redundancy of homologous genes.

7 o-sex chromosomes that contain a total of 12 homologous genes.

8 uman and mouse tumors or whether they affect homologous genes.

9 ng transcription of AcF3GT1 and AcANS or the homologous genes.

10 The annotations describe matches to human homologous genes.

11 a [FLNa], FLNb, FLNc) that originate from 3 homologous genes.

12 quence similarity to transfer annotations to homologous genes.

13 and was conserved in >50% of human and mouse homologous genes.

14 NA (known as siRNA) inhibits expression from homologous genes.

15 ery different reactions, they are encoded by homologous genes.

16 s or non-native probes derived from putative homologous genes.

17 create multiple crossover libraries from non-homologous genes.

18 randed RNA by sequence-specific silencing of homologous genes.

19 sponds to double-stranded RNA by suppressing homologous genes.

20 nce sequence the positions of all introns in homologous genes.

21 represented in the mouse by a cluster of six homologous genes.

22 ifficulty in studying expression patterns of homologous genes.

23 The interactions between MITEs and homologous genes across 19 accessions provided a fine so

24 Two adjacent homologous genes (alpA and alpB), which encode H. pylori

25 ults support the hypothesis that exchange of homologous genes among S. aureus genomes can play a role

26 nal BLAST searches that are used to identify homologous genes and combine them into two fundamentally

27 phs' to represent the assembly of reads from homologous genes and discuss potential applications of g

28 information in the public domain concerning homologous genes and their products increases greatly.

29 genomic context in operons containing other homologous genes, and distributions of conserved surface

30 . cruzi genome contains a large family of TS homologous genes, and it has been suggested that TS homo

31 es abundance, similarity between isoforms or homologous genes, and large data size all pose challenge

32 ganization, the low level of conservation of homologous genes, and the lack of many genes conserved i

33 y relevant cis-regulatory sequence change in homologous genes, and validate it using microarray data

34 Clusters of two or more homologous genes are abundant, totaling 1391 clusters co

35 mary literature, articles about well-studied homologous genes are added as references.

36 We show that homologous genes are present, and expressed, in a wide r

37 nd atTIC40, encode the Tic proteins, and two homologous genes, atHSP93-V and atHSP93-III, encode Hsp9

38 hosphate)-binding cassette (ABC) transporter-homologous gene, ATP11A.

39 yet no mutations have been described in the homologous genes beta- and gamma-synuclein.

40 A comparison of homologous genes between B. schlosseri and other diverse

41 In a comparison of the genomic sequences of homologous genes between C.elegans and Caenorhabditis br

42 r the conservation of expression patterns of homologous genes between distantly related species.

43 Substitution analysis of homologous genes between human and rodent also indicates

44 entists study macrosynteny, microsynteny and homologous genes between sequences.

45 Exchange of homologous genes between the two organisms showed that t

46 Here, we establish that finding the homologous gene block problem is NP-hard and APX-hard.

47 This signal specifies the cardiac field, and homologous genes (BMP2/4 and Nkx2.5) perform this functi

48 A pair of homologous genes, BnPMT6s, in two QTLs were identified a

49 -stranded RNA (dsRNA) inhibits expression of homologous genes by a process involving messenger RNA de

50 rely heavily on pre-computation to identify homologous genes by genome-wide comparisons.

51 onserved in Caenorhabditis elegans, in which homologous genes (called lin-2, lin-7, and lin-10) are r

52 which is a process by which the proximity of homologous genes can lead to a change in gene expression

53 Interactions between paired homologous genes can lead to changes in gene expression.

54 to the formation of novel structures and how homologous genes can regulate the disparate morphologica

55 oteins encoded by the reductive dehalogenase homologous genes CbdbA1092 and CbdbA1503 were specifical

56 atients retain at least one copy of a highly homologous gene, centromeric SMN ( SMN2 ).

57 We demonstrate here that the homologous gene cluster pilABCD in an otitis media isola

58 fungal symbiont, Neotyphodium uncinatum, two homologous gene clusters (LOL-1 and LOL-2) associated wi

59 Among a large number of homologous gene clusters in C. elegans, two gene familie

60 S. meliloti as suggested by the presence of homologous gene clusters in other bacterial genomes.

61 Pan-genome analysis identified 10,110 homologous gene clusters present only in a subset of str

62 A total of 331 homologous gene clusters were essential for fitness duri

63 Homologous gene clusters were found in genomes of other

64 In addition, we annotate the homologous genes containing cysteine (Cys) instead of Se

65 Because homologous genes control early developmental events as w

66 rs through both homologous crossing over and homologous gene conversion during meiosis.

67 t to high levels of recombination as well as homologous gene conversion, indicating that patterns pro

68 A set of homologous genes could be identified in Brassica napus t

69 ch in Arabidopsis thaliana is encoded by two homologous genes, CSN5A and CSN5B.

70 Plasmids carrying homologous genes cut at appropriate sites recombined eff

71 e DNA diversity of a noncoding region of the homologous genes DD44Y and DD44X, sampling S. latifolia

72 er-1106, observed in HRR25 (CKIdelta/epsilon homologous gene)-deleted Saccharomyces cerevisiae cells

73 Comparative analysis of inferred homologous genes derived from this model shows patterns

74 aracterized the full-length cDNAs of 3-OST-1 homologous genes, designated as 3-OST-2, 3-OST-3A, and 3

75 Five homologous genes, designated NnOMT1-5 and encoding polyp

76 yses in nonhuman primates (NHPs) reveal that homologous genes do not generate the same ascending and

77 nts KB25/pKJB5 at 44 degrees C, but the less homologous gene does not.

78 These two homologous genes encode small proteins containing a calc

79 oremediation of chlorinated solvents, reveal homologous genes encoding an incomplete Wood-Ljungdahl p

80 d IRX10 and IRX10-like (IRX10-L), two highly homologous genes encoding members of the glycosyltransfe

81 quencies of apparent gene conversion between homologous genes encoding outer membrane proteins.

82 Several homologous genes encoding proteins involved in regulatin

83 Mammals have three homologous genes encoding proteins with hyaluronan synth

84 Four homologous genes encoding SAPAP proteins have been previ

85 reonine protein phosphatase1) and FyPP3, two homologous genes encoding the catalytic subunits of prot

86 reonine protein phosphatase1) and FyPP3, two homologous genes encoding the catalytic subunits of Ser/

87 clude rapid cold-induced expression of three homologous genes encoding transcriptional activators, CB

88 The phenylalanine ammonia-lyase homologous gene encP from the "Streptomyces maritimus" e

89 yndrome) led us to study the role of two non-homologous genes, EVC and LBN, in heart development and

90 No homologous gene exists in any (non-H. pylori) organism.

91 This map was then compared to homologous gene expression in zebrafish, mouse, and shar

92 conserved, one possible model to account for homologous gene expression patterns, is conservation of

93 rom across-tissue differential expression to homologous gene expression.

94 HME results from mutations in one of two homologous genes, EXT1 and EXT2.

95 ssed gene display for the analysis of highly homologous gene families as demonstrated by its applicat

96 e can infer rooted species phylogenies using homologous gene families from complete genomes of 10 bac

97 blished sequences, and to detect potentially homologous gene families in both P. falciparum and Plasm

98 n dorsal columns of fly neurectoderm, and of homologous gene families in corresponding domains of ver

99 The differential gain and loss of genes from homologous gene families represents an important source

100 ntraction of KIR haplotypes as well as other homologous gene families that map in tandem.

101 structural and functional gene annotations, homologous gene families, multiple sequence alignments,

102 ncluding trinucleotide repeat expansions and homologous gene families, to facilitate their functional

103 ies phylogeny based on 36 genomes with 8,332 homologous gene families.

104 Our results suggested that highly homologous gene family members may function antagonistic

105 In vitro recombination of homologous genes (family shuffling) has been proposed as

106 Patterns of homologous gene flow among genomes of 12 strains from a

107 Homologous genes for both C-P lyase and phosphonatase de

108 portance of proteins encoded by positionally homologous genes for the cell tropism of other gammaherp

109 Homologous genes for this pathway are widespread in bact

110 ion, including the convergent recruitment of homologous genes for venom expression.

111 to explore the expression of this gene and a homologous gene, Foxp1, in the developing brain.

112 d by virus-mediated, transient expression of homologous gene fragments.

113 Both the homologous gene from E. faecalis V583 (EF1861) and E. co

114 on and molecular characterization of an ORC4-homologous gene from maize argues that, in its evolution

115 he substitution of S. pyogenes gacB with the homologous gene from Streptococcus agalactiae (Group B S

116 mid based expression of plmT2 or fos ORF4 (a homologous gene from the fostriecin biosynthetic gene cl

117 Cloning of the homologous gene from the mouse revealed 93% amino acid h

118 a coli, a gene fragment corresponding to the homologous gene from the pathogenic oral bacterium Porph

119 We have cloned and sequenced the homologous gene from Xenopus (Xenopus Dna2).

120 Our study identified homologous genes from Arabidopsis thaliana with known fu

121 and DeltaPpGbeta2 can be complemented by the homologous genes from Arabidopsis, AtXLG2 and AtAGB1, re

122 urther confirmation of this interaction, the homologous genes from Chlamydia trachomatis, serovar E,

123 acids that showed significant similarity to homologous genes from crayfish, insects, earthworms, and

124 targets are located at the same position in homologous genes from different plants; these either cou

125 rameshift signals are present in at least 21 homologous genes from different species, 2 of which are

126 homologous genes from each group underlie quantitative t

127 difficulties in metagenomic assembly is that homologous genes from evolutionarily closely related spe

128 soflavone synthase, and used them to isolate homologous genes from other leguminous species including

129 s but can be replaced by at least one of the homologous genes from other pathways.

130 share significant sequence similarities with homologous genes from other plants, the clade-specific f

131 uding ESTs derived from duplicated genes and homologous genes from related species.

132 validated by qRT-PCR, and compared with the homologous genes from S. japonica, a species in the same

133 e C4-Pepc and C4-Me genes from maize and the homologous genes from sorghum (Sorghum bicolor) and Seta

134 analysis of sequences from gene families and homologous genes from species of varying divergence can

135 To rectify this problem, we compare homologous genes from the budding yeast Saccharomyces ce

136 es encoding ShMKS1 and ShMKS2 as well as the homologous genes from the cultivated tomato, Solanum lyc

137 ation among these editases, we have isolated homologous genes from the Japanese pufferfish, Fugu rubr

138 or a convergent gene fusion involving a MutS-homologous gene functioning within the mitochondrion and

139 and their mechanism of export, we cloned the homologous genes (glnA1 and sodA) from the rapid-growing

140 ation genes, like the glutathione peroxidase homologous gene GPXH/GPX5 and the sigma-class glutathion

141 sharing a core cis-regulatory motif and each homologous gene group as sharing a homologous cis-regula

142 roup of genes specified by the user or among homologous gene groups; (3) inter-database comparative v

143 An unproven assumption is that homologous genes have a common ancestor.

144 Homologous genes have recently been shown to regulate st

145 Although homologous genes have yet to be inactivated in any other

146 ons and is mapped to chromosome 17; a highly homologous gene, hUAT2, maps to a nearby region of chrom

147 the single-gene-deficient mice by the intact homologous gene (i.e., hsp70.3 in hsp70.1-/- mice and vi

148 is AD model, with significant enrichment for homologous genes identified as differentially expressed

149 rged substantially, making identification of homologous genes impossible despite a separation of only

150 obolus heterostrophus Hypothesizing that the homologous gene in Coccidioides posadasii could be impor

151 A targeted deletion of the homologous gene in Listeria was generated, and in contra

152 Deleting the homologous gene in P. falciparum, PfDegP, similarly lowe

153 Knockout of the homologous gene in zebrafish recapitulated a heart failu

154 rice and barley and to a lesser extent with homologous genes in Arabidopsis.

155 Conserved effects on sleep-like behaviour of homologous genes in C. elegans and Drosophila suggest a

156 omparisons of intron-exon structures between homologous genes in different eukaryotic species have re

157 he same ligand to regulate the expression of homologous genes in different organisms.

158 tive mapping, which compares the location of homologous genes in different species, is a powerful too

159 The existence of homologous genes in diverse species is intriguing.

160 volved, and map-based cloning identified two homologous genes in duplicated regions of the genome.

161 There are two RAD54-homologous genes in human cells, hRAD54 and RAD54B.

162 We now report the identification of homologous genes in humans and mice encoding MGAT2.

163 ided important insights into the function of homologous genes in humans, such studies are necessarily

164 biosis genes are CASTOR and POLLUX, the twin homologous genes in Lotus japonicus that encode putative

165 on, they can be used to overexpress specific homologous genes in M. maripaludis.

166 ngus and is unique to filamentous fungi, but homologous genes in Magnaporthe, Ustilago, Aspergillus,

167 Mrr superfamily of homologous genes in microbial genomes restricts modified

168 ms and by analyzing site-specific changes in homologous genes in model systems such as the yeast Sacc

169 pported by independent expression data or by homologous genes in other species.

170 Homologous genes in plants including rice and potato ind

171 unavailable, thus sequence comparison among homologous genes in present-day organisms forms the core

172 were made to induce the four annotated Xa27 homologous genes in rice cultivar Nipponbare, but none o

173 imated that a minimum copy number of the p44-homologous genes in the genome is 18; (v) detected two d

174 ifferent mRNAs that are transcribed from p44-homologous genes in the HGE agent cultivated in HL-60 ce

175 Knockout or knockdown of the homologous genes in the higher plant model Arabidopsis t

176 dentification and characterization of highly homologous genes in the invertebrates Caenorhabditis ele

177 By contrast, knockouts of homologous genes in the mouse often do not exhibit compa

178 milar intron architecture, and therefore the homologous genes in these fungi are likely to use the sa

179 Distantly homologous genes in this region, US7, US8, US9, and US10

180 n subsequent generations, and can inactivate homologous genes in trans.

181 However, the deletion of the homologous genes in Y. pseudotuberculosis does not seem

182 By comparing yapK and yapJ to three homologous genes in Y. pseudotuberculosis IP32953 (YPTB0

183 For example, they share nine non-redundant homologous genes, including ribonucleotide reductase sma

184 , by connecting contigs with the guidance of homologous genes-information that is orthogonal to the s

185 Based on the presumed function of homologous genes involved in the biosynthesis of thiovir

186 ing animals and plants share common cores of homologous genes involved in the key processes of viral

187 I-PpoI-induced contact between homologous genes is abrogated by the transcriptional inh

188 nts a conserved linkage because the order of homologous genes is conserved.

189 d proposed that the functional similarity of homologous genes is primarily determined by the cellular

190 w report that the differential regulation of homologous genes is the mechanism responsible for the di

191 nes EGD-e and L. innocua CLIP 11262, contain homologous genes (lmo2764 and lin2907, respectively) tha

192 However, a handful of genes, including the homologous genes LNK1 and LNK2, are more strongly induce

193 Thus, two highly homologous genes, located in a head-to-head configuratio

194 and PCR analyses revealed disruption of the homologous gene locus in one fbpA::OmegaKm transformant

195 On the other hand, the order of exons within homologous genes (<2.5 kb) was preserved, as expected.

196 that the shared and divergent parts of these homologous genes may be involved in specifying the share

197 Nucleotide identities of homologous genes mostly varied by less than 1% within po

198 Deletion of two homologous genes, MRS3 and MRS4, that encode mitochondri

199 In addition to NY-BR-1, a homologous gene, NY-BR-1.1, was identified in this study

200 henomenon in which silencing among dispersed homologous genes occurs.

201 OsbHLH068, which is a homologous gene of AtbHLH112 that is up-regulated under

202 Gene-targeted knockdown of CYP2C55, the homologous gene of CYP2C9, demonstrated viability rescue

203 f ALS, in which the expression of dnc-1, the homologous gene of human dynactin-1, is knocked down (KD

204 of Staphylococcus epidermidis, but not in a homologous gene of the more aggressive human pathogen, S

205 or why the same mutation in highly conserved homologous genes of different species leads to different

206 H. saguini contains homologous genes of known virulence factors found in oth

207 egions of extreme codon conservation between homologous genes of related species.

208 and that none of them can be replaced by the homologous genes of the other mce operons.

209 human PTTG family consists of at least three homologous genes, of which PTTG1 is located on chromosom

210 We also identified a homologous gene on the Mus musculus X chromosome (MMUX)

211 ugView is a Java application for visualizing homologous genes on a pair of related genomes, and can a

212 Clustering of co-expressed, non-homologous genes on chromosomes implies their co-regulat

213 If the two groups consist of two homologous genes, one from each individual, the IBD is c

214 le sets of chemotaxis genes, the deletion of homologous genes or even different genes in the same ope

215 y predicted by transferring annotations from homologous genes or proteins for which experimental evid

216 lignments and trees representing families of homologous genes or proteins.

217 ome) can be assigned to one of two groups: X-homologous genes or testis-specific gene families with n

218 the molecular basis of how these two highly homologous genes orchestrate their diverse functions rem

219 rom multiple sequence alignments of putative homologous genes (orthologs and paralogs) and further ut

220 KEY MESSAGE: The homologous genes OsbHLH068 and AtbHLH112 have partially

221 Here, two rice CCR4 homologous genes, OsCCR4a and OsCCR4b, were identified.

222 s displaying V(D)J-mediated immunity, and no homologous gene pair has been identified in other organi

223 of this question we asked whether mouse X-Y homologous gene pairs are expressed in brain in a sex-sp

224 analysis results such as synteny blocks and homologous gene pairs between different cucurbit species

225 Structural variations distinguish homologous gene pairs characterized by divergent promote

226 gate the partial coding sequence for 56 more homologous gene pairs from the neo-sex chromosomes.

227 Approximately 12 X-Y homologous gene pairs have been identified in the non-re

228 ust to gene expression levels and removal of homologous gene pairs.

229 mutations in PDE6A and those reported in the homologous gene PDE6B encoding the beta subunit of rod c

230 Work on homologous genes present in Escherichia coli suggests th

231 ion of numerous flexible gene modules, where homologous genes present in the pan-genome interchange t

232 The homologous gene product of myxomavirus (MV), M153R, was

233 21, but not in the syp122 mutant lacking the homologous gene product; the delay was rescued by comple

234 e amino acid sequence similarity between the homologous gene products and MUM2.

235 This process often yields homologous gene products exhibiting diverse functions.

236 of the Hpa RXLR effector gene HaRxL96 and a homologous gene, PsAvh163, from the Glycine max (soybean

237 plication events can be used to discriminate homologous genes, QuartetS uses an approximate phylogene

238 ccharomyces cerevisiae where deletion of the homologous gene RAD27 results in genome instability and

239 apeutic agents in gene therapy by initiating homologous gene recombination and repair.

240 ing, c-IAP1-deficient mice were generated by homologous gene recombination.

241 at removing low quality clusters of putative homologous genes recovered by heuristic-based approaches

242 The family is composed of five highly homologous genes referred to as TAFA-1 to -5.

243 erial symbionts and pathogens each contain a homologous gene region necessary for the synthesis and t

244 Four homologous genes regulated as part of the AFT1-regulon (

245 herefore, by combining chemical genetics and homologous gene replacement in somatic cells, we reveal

246 Using mutagenesis and homologous gene replacement in Tetrahymena thermophila,

247 analysis of an archaeon, we have developed a homologous gene replacement strategy for Halobacterium s

248 LEU2 was replaced by ADE1, preventing simple homologous gene replacement to become Leu2(+).

249 sertional mutagenesis, chemical mutagenesis, homologous gene replacement, conditional knockdown techn

250 out mutations in tomato SlHAK20 and the rice homologous genes resulted in hypersensitivity to salt st

251 thaliana accessions, this locus contains two homologous genes, RPW8.1 and RPW8.2.

252 We examined sequence variation in 18 homologous gene segments (including nearly 10,000 base p

253 g the CREB gene by transfecting cells with a homologous gene sequence double-stranded RNA drastically

254 ic applications, with particular emphasis on homologous gene sequences among mammals.

255 here was specific competition for binding by homologous gene sequences but not by pUC nor Bacillus su

256 ication designed for comparative analysis of homologous gene sequences either from multigene families

257 and unique short (US) genomic regions, where homologous genes share a high degree of colinearity and

258 f DNA and amino acid identity for 65% of the homologous genes shared by the two genomes.

259 Comparison of expression of eight ABI5-homologous genes shows overlapping regulation by ABI3, A

260 Homologous gene silencing was validated by reverse trans

261 are the expression pattern with those of the homologous genes SorCS1 and SorCS2.

262 oss-of-function mutants of SPL10 and its two homologous genes, SPL2 and SPL11, flowered late compared

263 those in genes with a small number of known homologous gene structures, show a significant correlati

264 on of functional features of dog-human-mouse homologous genes suggests that the dog might have underg

265 Finally, we identify a homologous gene, syne-2, that is expressed in an overlap

266 Recent studies entailing homologous gene targeting and mutation of WI-1 have prov

267 We created an Ercc1 mutant through homologous gene targeting.

268 e function has been hampered by obstacles to homologous gene targeting.

269 ted lactoferrin knockout (LFKO(-/-)) mice by homologous gene targeting.

270 we generated mice deficient in XIAP through homologous gene targeting.

271 In addition, there are four TipE-homologous genes (TEH1-4) in D. melanogaster and three t

272 In a nonrestoring genotype we identified a homologous gene that exhibits a deletion in the promoter

273 numerous pseudoparalogs were detected, i.e. homologous genes that apparently were acquired by early

274 t it is composed of approximately 100 highly homologous genes that are found only in mycobacteria.

275 RGA and GAI are homologous genes that encode putative transcriptional re

276 ogs are two fundamentally different types of homologous genes that evolved, respectively, by vertical

277 We show that Nematostella uses homologous genes to achieve bilateral symmetry: Multiple

278 ion systems create opportunities for testing homologous genes to increase competence of transformatio

279 Cosuppression, the silencing of dispersed homologous genes triggered by high copy number, may have

280 rom different metagenomes, we show a pool of homologous gene variants co-exist for each module in eac

281 sed in Escherichia coli strains in which the homologous gene was mutated.

282 nment of sea urchin gene models to groups of homologous genes was accomplished by BLAST alignment and

283 An algorithm for detecting local clusters of homologous genes was applied to the genome of Caenorhabd

284 correlation of transposition hot spots among homologous genes was poor.

285 UTR1, cytosolic NAD kinase, and YEF1, a UTR1-homologous gene we characterized as encoding a low speci

286 ent (i.e., CELLULOSE SYNTHASE1) and expansin homologous genes were all down-regulated, indicating the

287 Mutations in homologous genes were identified in the barley eceriferu

288 Homologous genes were subsequently identified in other i

289 Two homologous genes were suggestively associated: BCOR (Xp1

290 ten is compounded by the tight clustering of homologous genes, which precludes the generation of mult

291 50 (CYP) 2B1 and 2B2 proteins are encoded by homologous genes whose promoters contain a mammalian-app

292 strain of H. ducreyi (35000HP) contains two homologous genes whose protein products have estimated m

293 for the simultaneous inactivation of several homologous genes with a single transgene.

294 method for simultaneously identifying novel homologous genes with identical structure in the human,

295 screens are limited in the identification of homologous genes with overlapping functions.

296 ay profile of mammalian nociceptors revealed homologous genes with potentially shared nociceptive fun

297 Homologous genes within the flavonoid pathway for C. sal

298 hat regulatory interactions between pairs of homologous genes within the same cell can lead to under-

299 hereas the expression of YOL002c and a third homologous gene, YOL101c, was induced by high zinc.

300 to reflect the presence of a second, highly homologous gene, ZmMrp4, that is also coregulated with t