ライフサイエンスコーパス: homologous sequence

1 the synaptic complex that is stabilized on a homologous sequence.

2 factor-related protein 2 (HRP2), contains a homologous sequence.

3 he Rad51 filament to search the genome for a homologous sequence.

4 lb probes failed to reveal expression of the homologous sequence.

5 es can be obtained using less than 100 bp of homologous sequence.

6 ate, this sequence was replaced by an IS1294-homologous sequence.

7 lls against infection with viruses bearing a homologous sequence.

8 , especially for difficult proteins with few homologous sequences.

9 x epigenetic interactions that occur between homologous sequences.

10 ngle-strand annealing (SSA) between flanking homologous sequences.

11 translocation of dsDNA during the search for homologous sequences.

12 of new genomes regardless of availability of homologous sequences.

13 eins of known structure, we find prolines in homologous sequences.

14 simultaneously aligns and annotates pairs of homologous sequences.

15 le partnering selectivity despite the bZIPs' homologous sequences.

16 proteins that function in the eye and their homologous sequences.

17 s of the genome to quickly identify possible homologous sequences.

18 rees so derived can be examined directly for homologous sequences.

19 ng data in secondary structure prediction to homologous sequences.

20 ns, and specificity in distinguishing highly homologous sequences.

21 ry variation, as defined by the alignment of homologous sequences.

22 dentified a 100-kDa protein without database homologous sequences.

23 mbers of transgenic loci and repeated use of homologous sequences.

24 tly disrupt the activity of genes containing homologous sequences.

25 high accuracy, even for sequences with fewer homologous sequences.

26 , repair was about 14% of that of completely homologous sequences.

27 l 8 bp test to rapidly reject almost all non-homologous sequences.

28 features deduced from a single structure and homologous sequences.

29 more accurate contact predictions from fewer homologous sequences.

30 gent molecular clones with short overlapping homologous sequences.

31 as-yet-unknown 3D structure given sufficient homologous sequences.

32 (DMC1) recombinases, mediate the search for homologous sequences.

33 has led to an explosive growth of unaligned homologous sequences.

34 identified and cloned a cDNA based on nSMase homologous sequences.

35 ; and compared IS-interrupted sequences with homologous sequences.

36 optimized for identifying different types of homologous sequences.

37 ultiple clusters constituting unrelated (non-homologous) sequences.

38 olecule containing the almost identical, or "homologous, " sequence.

39 r reaction), specific (discrimination of 95% homologous sequences, 1 in > or =20,000), and quantitati

40 3997 coding sORFs with readily identifiable homologous sequences, 2376 are subject to purifying sele

41 s nucleotide contacts in a sequence from its homologous sequence alignment across different species.

42 remains difficult to address by conventional homologous sequence alignment approaches.

43 y of one seed model over another, a model of homologous sequence alignment must be chosen.

44 In this paper, we assume a model of homologous sequence alignment which includes indels and

45 PANDIT is a database of homologous sequence alignments accompanied by estimates

46 Using homologous sequence alignments of proteins previously ch

47 A large database of homologous sequence alignments with good estimates of ev

48 A large, high-quality database of homologous sequence alignments with good estimates of th

49 om phenotypic observations or comparisons of homologous sequences among closely related species.

50 ynaptic filaments are sufficient to locate a homologous sequence and form initial joints, even on the

51 TGF-beta(2) peptide containing the homologous sequence and Trp-52 was as active as the TGF-

52 protein using information from only a set of homologous sequences and (if available) a single structu

53 od for sensitive MSA construction, which has homologous sequences and alignments created from multi-s

54 gulation has been generally found to silence homologous sequences and collectively called RNAi.

55 81 suppresses template switches between both homologous sequences and diverged human Alu repetitive e

56 er membrane proteins from the organism share homologous sequences and have been suggested to function

57 ingle genomic sequence, in a pair of aligned homologous sequences and in a set of functionally relate

58 ls that assemble the sequence data, annotate homologous sequences and interrogate it to reveal regula

59 Homologous sequences and potential base pairing were fou

60 ry broad outline of how these proteins align homologous sequences and promote DNA strand exchange has

61 Thus, notwithstanding the highly homologous sequences and similar functions, the RNA m(5)

62 uperfamily of phosphotransferases that share homologous sequences and structural motifs and have many

63 hnique used by molecular biologists to group homologous sequences and study evolution.

64 nied by a deletion that spans one of the two homologous sequences and the intervening sequence, if an

65 he nucleus: those that act between dispersed homologous sequences and those that act to align and pai

66 CbAgo induces DNA interference between homologous sequences and triggers DNA degradation at dou

67 integrating information from the literature, homologous sequences, and database searches.

68 of the target alcohol dehydrogenase gene as homologous sequences, and neomycin phosphotransferase an

69 , to compare the pig X and Y Chromosomes for homologous sequences, and thereby to reveal mechanisms u

70 While direct repeats and imperfectly homologous sequences appear to mediate the formation of

71 y protein for which a tertiary structure and homologous sequences are available, and will facilitate

72 ion occurs at high frequencies even when the homologous sequences are hundreds of bases away from the

73 low accuracy, especially when the available homologous sequences are limited.

74 rthermore, the results suggest that when non-homologous sequences are present at the proximal end, AT

75 Our analysis suggests that Cs1-homologous sequences are present in low copy number in s

76 ith >30 paralogues in the genome of Bgh, and homologous sequences are present in other formae special

77 FgFCO1 devoid of calcium binding motif whose homologous sequences are present in various glycoside hy

78 Many Dal80p binding site-homologous sequences are relatively evenly distributed a

79 arlsbergensis ARS elements revealed that the homologous sequences are required for function.

80 However, when extensive homologous sequences are restricted to one side of the D

81 Homologous sequences are sometimes similar over some reg

82 Homologous sequences are then compiled with the input se

83 compositions determined by our method among homologous sequences are useful in sequence validation,

84 ther homology-directed repair (HDR), using a homologous sequence as a repair template, or nonhomologo

85 tentially error-free process that utilizes a homologous sequence as a repair template.

86 Using these homologous sequences as probes, we identified an express

87 A homologous sequence at a distance from the break site af

88 ted, and thiolate cysteines are clustered in homologous sequences at both the amino and carboxy termi

89 through recombination between the conserved homologous sequences at the 3' end of V(H).

90 o selectively pair oligonucleotides to their homologous sequences at the ends of fragments of duplex

91 Despite a tandem array of highly homologous sequences at the transgenic locus, no gene si

92 ure that have a sufficient number of diverse homologous sequences available, this combined method (EV

93 roves structure prediction accuracy of other homologous sequences beyond the accuracy obtained by seq

94 Y. pestis CO92, biovar Orientalis, revealing homologous sequences but a remarkable amount of genome r

95 tures of two IgG binding domains with highly homologous sequences but different three-dimensional str

96 four-way junction containing a 12 bp core of homologous sequences but has no activity on another four

97 ent of a rapid comparative modeling tool for homologous sequences by extension of the TASSER methodol

98 coring matrix to reflect the identity of the homologous sequence can correct higher identity overexte

99 which large multiple sequence alignments of homologous sequences can be compiled.

100 a wide variety of organisms have shown that homologous sequences can exert a significant impact on e

101 Collections of multiple homologous sequences can provide critical information to

102 NA end by the nuclease is required to reveal homologous sequences capable of being paired by ICP8.

103 for Lk73.5 is followed by another partially homologous sequence containing an ORF (sph-like 2) for a

104 f these chimeras indicate that exchange with homologous sequences could be tolerated, up to V17eco/T1

105 re coordinated approach focused on gathering homologous sequence data will greatly facilitate such ef

106 sign probes for both whole-genome and highly homologous sequence data.

107 Comparisons with available homologous sequences demonstrate subtype switching of U1

108 ure Alignment Database (HOMSTRAD) to include homologous sequences derived from the protein families d

109 On the other hand, some homologous sequences did not appear to be competent to e

110 distinct beta subunit genes each encode five homologous sequence domains (D1-5), three of which (D1,

111 e analysis method has been the comparison of homologous sequence domains in related but moderately ev

112 eases produce single strand ends that engage homologous sequences either by strand invasion or strand

113 the syntenic mouse regions although 13 have homologous sequences elsewhere in the mouse genomic sequ

114 enzymes (FucT III, V, and VI) having highly homologous sequences, especially in the catalytic domain

115 d across the fly genome that pair with their homologous sequences, even when relocated to multiple po

116 ntrast, vectors containing <1,500 bp between homologous sequences exhibited lower frequencies of dele

117 In apes, homologous sequences exist only on the X chromosome.

118 hould exist, which accommodate dozens of non-homologous sequence families.

119 In the other two families, no homologous sequence flanking the breakpoints was found,

120 small duplexes of RNA specifically target a homologous sequence for cleavage by cellular ribonucleas

121 get sequence were only silenced by the exact homologous sequence for each.

122 taining high quality alignments of divergent homologous sequences for cross-species sequence comparis

123 Homologous sequences for Ehrlichia chaffeensis p28 were

124 ysis of conservation profiles in families of homologous sequences for nine proteins whose folding nuc

125 t analysis is a powerful technique to screen homologous sequences for putative HGTs and is useful in

126 ate autonomously in D. radiodurans and carry homologous sequences for replacement recombination in th

127 A is a multi-step modeling process, in which homologous sequences for the target sequence are selecte

128 more surprisingly, they have also shown that homologous sequence fragments make largely additive cont

129 f a deletion on a recipient plasmid with the homologous sequence from a donor plasmid in human cells.

130 residues of mouse band 3 are replaced by the homologous sequence from human band 3, including the nor

131 ino acid spacer with a sequence based on the homologous sequence from subunit B of Pyrococcus horikos

132 is segment could be replaced with mostly non-homologous sequence from the SLC19A2 thiamine transporte

133 y deletion of AXH or by replacement with the homologous sequence from the transcription factor HBP1,

134 ogram SIM were evaluated on 257,716 pairs of homologous sequences from 100 protein families.

135 d through alignment of Arabidopsis CBF1 with homologous sequences from a diverse array of plant speci

136 flowering plant Arabidopsis, is conserved in homologous sequences from all lineages of land plants, i

137 c domain of RPS2 and N, were used to amplify homologous sequences from Arabidopsis thaliana.

138 By comparison of the 1.1-kb element to homologous sequences from Caenorhabditis briggsae, we id

139 tion, and in two cases, D2 could accommodate homologous sequences from D1, which forms a heterodimer

140 repared several chimeric FIXa proteins using homologous sequences from factor VII (FVII): FIXa(FVIIEG

141 repared several chimeric FIXa proteins using homologous sequences from FVII: FIXa(FVIIEGF2) (FIX Delt

142 x virus type 1 (HSV-1) genome is replaced by homologous sequences from HSV-2.

143 bstituted amino acid sequences of IFE-5 with homologous sequences from IFE-3.

144 By extending this analysis to include homologous sequences from numerous Y. pestis and Y. pseu

145 Phylogenetic analysis of homologous sequences from other genera revealed that thi

146 s of all deduced FDLV protein sequences with homologous sequences from other Paramyxoviridae indicate

147 of the E. coli b subunits were replaced with homologous sequences from the b and b' subunits of Therm

148 Moloney murine leukemia virus (M-MuLV) with homologous sequences from the FeLV-945 LTR.

149 ing organisms, rates were calculated for the homologous sequences from the haptophyte Emiliania huxle

150 ts on high-throughput mouse sequences, using homologous sequences from the human genome, TWINSCAN sho

151 which one or two regions were replaced with homologous sequences from the other type.

152 ed in which US2 sequences were replaced with homologous sequences from US3, an HCMV glycoprotein that

153 e annotations stored in the database include homologous sequences from various sequence databases, do

154 Homologous sequences have a much lower global similarity

155 similarity to any other known apyrases, but homologous sequences have been found in the genome of th

156 Mutagenesis studies and alignments of homologous sequences have demonstrated that protein func

157 ximately 400 expressed transcripts for which homologous sequences have not yet been identified in oth

158 e sequence Gly-His-Arg-Pro- (GHRP-), but the homologous sequence in chicken fibrin begins with the se

159 siepsilonRACK sequence in epsilonPKC and its homologous sequence in epsilonRACK constitutes a change

160 nce probe failed to identify a corresponding homologous sequence in genomic DNA from group O pigs, th

161 ch query gene in a focal species compared to homologous sequence in target species.

162 regulatory module as a template identified a homologous sequence in the CFTR R domain and Slc26a6 sul

163 eologous sequence was positioned adjacent to homologous sequence in the donor but not when homeologou

164 ly of proteins binds to the PCS and a partly homologous sequence in the enhancer region of the LCR hy

165 stem-loop in bacterial 16S rRNA and that the homologous sequence in the human mitochondrial 12S molec

166 fy specific DNA sequences among thousands of homologous sequences in a database.

167 LV-945, or the LTR only, was substituted for homologous sequences in a horizontally transmissible pro

168 one-half of the assembled contigs identified homologous sequences in Arabidopsis (Arabidopsis thalian

169 that a conformational determinant requiring homologous sequences in both the VP2 puff and VP1 loop r

170 Homologous sequences in Caenorhabditis elegans and in pr

171 binations caused by the presence of repeated homologous sequences in CFH and CFHR1-R5 genes.

172 However, the presence of homologous sequences in closely related but nonpathogeni

173 s, gapping, and recombinational repair using homologous sequences in donor mtDNA.

174 six Arabidopsis ecotypes revealed 4-11 Tag2-homologous sequences in each, indicating that this eleme

175 ng and handling transgenic plants to silence homologous sequences in fungi grown on these plants.

176 protein sequence, and uses BLAST to identify homologous sequences in GO annotated databases.

177 ine whether recognition of H5 was limited to homologous sequences in H1, the most closely related HA

178 d expressed sequence tag searches identified homologous sequences in murine, porcine, and canine data

179 of the phylogenetic relationships among the homologous sequences in order to make more accurate pred

180 of the phylogenetic relationships among the homologous sequences in order to make more accurate pred

181 Detecting homologous sequences in organisms is an essential step i

182 A search of gene databases revealed homologous sequences in other members of the Fabales and

183 analysis, PGA1 and PGA2 are the only Galpha homologous sequences in pea.

184 revised nomenclature that is consistent with homologous sequences in related species.

185 could take place in the absence of undamaged homologous sequences in repair-proficient cells, suggest

186 and are removed from the pool if they match homologous sequences in that previously reorganized geno

187 ting molecule, which invade their respective homologous sequences in the chromosome, leading to repla

188 Recombination between the vector and homologous sequences in the co-transformed mammalian DNA

189 human glandular kallekrein 2 (HK2), have no homologous sequences in the databases that originate fro

190 ions is equally impeded by insertions of non-homologous sequences in the dsDNA, inserts of 6 base pai

191 s were further associated with 99 582 unique homologous sequences in the HSSP database, which increas

192 minant in molecular-grade water, a series of homologous sequences in the ITS region that are common t

193 are composed of six LNS repeats, named after homologous sequences in the Laminin A G domain, Neurexin

194 Highly homologous sequences in the murine, bovine, and porcine

195 on across flanking regions in the donors and homologous sequences in the recipients.

196 Comparison of fully sequenced Rp1-homologous sequences in the region demonstrates a histor

197 hich have distinct env genes but have highly homologous sequences in the rest of the genome.

198 lfotransferase gene family, which shares two homologous sequences in their catalytic domains.

199 bility of hairpin-produced siRNAs to silence homologous sequences in trans is subject to local chroma

200 ae strand transfer protein, Rad51, seeks out homologous sequences in vivo can be modeled by an in vit

201 ted anti-inflammatory properties of factor X homologous sequences in vivo.

202 ciated sulfotransferases cloned before share homologous sequences including the RDP motif.

203 esults indicate that linear distance between homologous sequences increases the rate of template swit

204 e-dimensional structure or a large number of homologous sequences, indicating a broad applicability o

205 g proteins appear to mediate the transfer of homologous sequence information from the maternal to the

206 Noticeably, most of the homologous sequences inherited from both parents were lo

207 s genome, we investigated whether repetitive homologous sequences inserted into E1-deleted adenoviral

208 Homologous sequence inside the cut sites was detrimental

209 mitrella patens, transforming DNA containing homologous sequences integrates predominantly by homolog

210 We then improved the method by including homologous sequences into the calculation of residue com

211 A homologous sequence is also present upstream of the huma

212 ning (EJ) pathway for repair of DSBs when no homologous sequence is available.

213 These results suggest that the homologous sequence is not compensating for a lack of SB

214 ividual DNA segments can be inhibited if the homologous sequence is placed within the parental somati

215 econstruction of tree topology from a set of homologous sequences is one of the main goals in the stu

216 g of the human BLM gene was confirmed by its homologous sequence, its chromosomal location, and by de

217 ated in the germline nucleus, that recognize homologous sequences leading to their removal.

218 nce on Rad59p, again being greatest when the homologous-sequence length was short.

219 , was defective for SSA, especially when the homologous-sequence length was short; however, even with

220 s and have difficulty discriminating between homologous sequences, limiting their therapeutic applica

221 eins to perfectly align the damaged DNA with homologous sequence located elsewhere in the genome.

222 le-strand breaks by gene conversions between homologous sequences located on different Saccharomyces

223 Such HR events between dispersed homologous sequences may result in not only deletions, b

224 rcus ribozyme was constructed by identifying homologous sequence motifs in rRNA.

225 ns are highly tolerant to recombination with homologous sequences (mutation by recombination is conse

226 bit Th17 polarization and cross-react with a homologous sequence of a Clostridium perfringens adenosi

227 ted Mac-1 in which M25 was replaced with the homologous sequence of CD11c, co-precipitated with uPAR.

228 mino acids within the linker of CaR with the homologous sequence of mGluR1, however, preserved recept

229 including the isogenicity and the length of homologous sequence of the targeting vector and the loca

230 l (S. beecheyi) were completely identical to homologous sequences of B. washoensis, strongly suggesti

231 representative isolate was identical to the homologous sequences of Brucella abortus, B. melitensis,

232 Homologous sequences of delta-conotoxins from two groups

233 Previously the efficiency of SSA, using homologous sequences of different lengths, was measured

234 Mutual recognition of homologous sequences of DNA before strand exchange is co

235 ndard global alignment programs to recognize homologous sequences of lower similarity.

236 and does not depend on the ability to align homologous sequences of specific genes.

237 In some cases, we also downloaded published, homologous sequences of the ITS region of fungi inspecte

238 ne revealed 4 Rp1 homologs and 18 other gene-homologous sequences, of which at least 16 are truncated

239 The level of conservation between two homologous sequences often varies among sequence regions

240 some can be repaired by recombination with a homologous sequence on a heterologous chromosome, withou

241 as shown to take place between Abeta and its homologous sequence on APP.

242 plate but also the capacity to interact with homologous sequence on heterologous chromosomes.

243 This requires an understanding of the XY-homologous sequence on these chromosomes.To this end, we

244 data exhibited a high level of synteny with homologous sequences on the wheat and/or rice syntenous

245 erally conserved for function across distant homologous sequences, one crucial structural feature is

246 ree Streptomyces, but unaffected by resident homologous sequences or inactivation of recA in M. smegm

247 nomic DNA and a linearized vector containing homologous sequences, or hooks, to the gene of interest.

248 No homologous sequences, other than erh orthologs, have bee

249 h insufficient evolutionary information (<10 homologous sequences), our method outperforms the SIFT a

250 odel building and improved identification of homologous sequences, particularly remote homologs.

251 sis of a deletion mutant lacking the amidase-homologous sequence, phi11(Delta181-381), revealed that

252 are maximal for Zr1 and Zr7, the two highly homologous sequences present in all muscle isoforms.

253 e can be increased 6-fold by the presence of homologous sequences previously shown to permit base pai

254 teins share only 5% sequence identity in the homologous sequence regions.

255 on for the lack of SBEI by expression of the homologous sequence reported by Kim et al., agenomic fra

256 e of yeast cyclophilin CPR1 by replacing its homologous sequence resulted in a hybrid molecule with s

257 Systematic comparison of these homologous sequences resulted in identification of a con

258 t degradation of messenger RNAs that contain homologous sequence(s).

259 However, inclusion of non-homologous sequence segments into a profile causes its c

260 he C(beta) density, and a score derived from homologous sequences, SIFT.

261 e point of giving complete alignments of non-homologous sequences, Stemloc-AMA aligns only sequences

262 proficient cells in the absence of undamaged homologous sequences, suggesting the existence of an ICL

263 requirement of transcription of euchromatic homologous sequences, suggests a role of double stranded

264 atural systems, their sequences have 2-fold (homologous) sequence symmetry.

265 A, to form a complex in which the search for homologous sequences takes place.

266 otypes and that this event was mediated by a homologous sequence that was once again missing from the

267 Vs were caused by segregation of single-copy homologous sequences that are located in non-allelic pos

268 identified hotspots of genetic variation in homologous sequences that correspond to variation in bio

269 gonucleotides was efficient for targeting to homologous sequences that were close to or distant from

270 cient evolutionary information (with not <10 homologous sequences), the performance of our method is

271 Using 8-12 homologous sequences, the algorithm correctly identifies

272 Overextended alignments include non-homologous sequences; they occur most frequently between

273 ks and the availability of a large number of homologous sequences through high-throughput sequencing.

274 ocating a branched junction from a fixed non-homologous sequence to all possible dimeric symmetric se

275 conversion, non-reciprocal transfer from one homologous sequence to another, is a major force in evol

276 2 (G-PNA) hybridizes with a DNA dodecamer of homologous sequence to form a four-stranded quadruplex.

277 It is unclear whether R simply serves as a homologous sequence to mediate the strand transfer or co

278 rkov model method HMMER3 to correctly assign homologous sequences to >13,000 manually curated familie

279 oteins that do not have sufficient number of homologous sequences to derive reliable co-evolution pro

280 The purpose of this study is to use multiple homologous sequences to infer a conserved RNA structure.

281 We added homologous sequences to the structural alignment.

282 ars to be at least two mechanisms that bring homologous sequences together within the nucleus: those

283 the relative position and orientation of the homologous sequences used for repair.

284 ting the structure conserved across multiple homologous sequences using the TurboFold algorithm.

285 at all vectors in which the distance between homologous sequences was >1,500 bp deleted at very high

286 d pmtA homologues were cloned from PAO1, and homologous sequences were found in almost all of the P.

287 Highly homologous sequences were found in mouse, Drosophila, an

288 No homologous sequences were identified from outside the pl

289 Two of the three homologous sequences were susceptible to citrullination,

290 f the gene was present in B. pilosicoli, and homologous sequences were widely conserved among porcine

291 events involving relatively short (<200 bp) homologous sequences, where RecA-mediated recombination

292 ingent on the existence of a large number of homologous sequences which are being rapidly made availa

293 s are in contact by analysing covariation in homologous sequences, which aids in the prediction of pr

294 s; and (2) recombinations between the nearby homologous sequences, which can delete genes in individu

295 structure perform similarly to ones based on homologous sequences, while combining sequence and struc

296 tems make up the bulk of the changes between homologous sequences, while unpaired regions are relativ

297 arameter sets should be used in alignment of homologous sequences with a stringent parameter set for

298 HBB genes and strong discrimination against homologous sequences within CCR2 and HBD.

299 rangements can be altered by the presence of homologous sequences within the maternal somatic nucleus

300 based on MD simulations of Ii transmembrane homologous sequences, yields a similar structure that is