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1 aments consist entirely of a single isoform (homotypic).
2 N1)pdm09 recipients, the PPAb titers against homotypic A(H1N1)pdm09 vaccine were similar to those aga
8 o aggregation are not fully accounted for by homotypic adhesion, and that further factors influence t
9 sible for its unique properties of increased homotypic adhesion, apoptosis resistance and budding.
10 of leukocyte migration that is initiated by homotypic adhesive interactions between platelets, leadi
12 human neutrophils causes rapid (</= 30 min) homotypic aggregation and NET release by a mechanism tha
14 undergo a rapid, ECM-dependent mechanism of homotypic aggregation and NETosis in response to C. albi
20 of recombinant Ub precursors to give various homotypic and even branched Ub probes at multi-milligram
21 ignaling mechanism for pseudokinases whereby homotypic and heterotypic association is used to assembl
22 targeting sequence, and participates in both homotypic and heterotypic associations with itself and L
24 ace and programed cell-cell adhesion between homotypic and heterotypic cells via sequence-specific DN
28 ted by the ability of Hax-1 proteins to form homotypic and heterotypic dimers with binding affinities
30 both steady-state and kinetic properties of homotypic and heterotypic GJ channels composed of these
32 These studies yield a set of rules regarding homotypic and heterotypic interactions that are likely t
33 A (NTD and CTD, respectively) engage in both homotypic and heterotypic interactions to create the cap
34 s share highly conserved C-termini mediating homotypic and heterotypic interactions within and betwee
37 ional intercellular communication in several homotypic and heterotypic populations by visualizing the
39 , NS1-CDN vaccinations conferred significant homotypic and heterotypic protection from DENV2-induced
43 connectivity was found both between similar (homotypic) and different (heterotypic) types of cells, w
46 that the ability of mRNAs to self-sort into homotypic assemblies is an inherent property of an messe
49 While the SSPE F required the presence of a homotypic attachment protein, MeV H, in order to fuse, M
52 eles, only IGLV3-21*01 facilitates effective homotypic BCR-BCR interaction that results in autonomous
55 equently observed, the mechanistic basis for homotypic binding site synergy is poorly understood.
57 cell surface receptor that identifies kin by homotypic binding, and in so doing exchanges outer membr
60 functions as a retention factor, increasing homotypic cell adhesion and limiting tumor spreading to
65 cell death initiated by actomyosin-dependent homotypic cell-in-cell invasion that can be observed in
66 Therefore, our data uncover the existence of homotypic cell-to-cell communication among mobile innate
69 TFs, helping to explain the observation that homotypic chains of binding sites express at low levels.
72 timulated DSG3-CAART IFN-gamma secretion and homotypic clustering, consistent with an activated pheno
73 act as direct drivers of gene expression in homotypic clusters of binding sites, independent of spac
74 ltiple copies of single mRNAs organize into 'homotypic clusters' that occupy defined positions within
75 ranules) are composed of RNA, in the form of homotypic clusters, and proteins required for germline d
76 ctor binding site (TFBS) patterns, including homotypic clusters, heterotypic clusters, and enhanceoso
80 KIT mutations, reveals that the strength of homotypic contacts and the cooperativity in the action o
81 ative interactions mediated by multiple weak homotypic contacts between receptor molecules are respon
83 uture occurrences of both the same disorder (homotypic continuity) and other disorders (heterotypic c
87 ct of the heavily studied coding benefits of homotypic coupling to heterotypic coupling across parall
89 gardless of the specific type of GJ channel (homotypic Cx43 and Cx45, and heterotypic Cx43/Cx45 and C
90 ermore, these mutations induced formation of homotypic DC clusters, which represent close correlates
92 rate phages that are either closely related (homotypic defence) or unrelated (heterotypic defence) to
95 ally forms heterodimers with Dpp rather than homotypic dimers, providing a possible explanation for t
97 have evolved means to preferentially take up homotypic DNA containing short and genus-specific sequen
99 cadherin recapitulated this outcome, whereas homotypic E-cadherin engagement promoted apoptotic signa
100 s in spatial chromatin conformation based on homotypic enhancer association, resulting in cooperative
103 further highlight the potential relevance of homotypic Fab:Fab interactions in targeting oligomeric c
106 ety with polarized fluorescent light elicits homotypic Forster resonance energy transfer (homo-FRET),
108 lysosome depends on the GTPase Rab7 and the homotypic fusion and protein sorting (HOPS) complex, but
109 vacuole/endosome tethering (CORVET) and the homotypic fusion and protein sorting (HOPS) complexes, w
110 d Vps41, independent of their known roles in homotypic fusion and protein sorting (HOPS)-mediated ves
111 We find that the tethering complex HOPS (homotypic fusion and protein sorting); the small GTPases
112 ntify VPS39-a gene encoding a subunit of the homotypic fusion and protein-sorting (HOPS) complex-as a
114 vacuole/lysosome, they are integrated by the homotypic fusion and vacuole protein sorting (HOPS) comp
115 -to-lysosomal trafficking, controlled by the homotypic fusion and vacuole protein sorting (HOPS) comp
117 lian homolog of yeast VPS41, a member of the homotypic fusion and vacuole protein sorting (HOPS) comp
119 , a component of the endolysosomal tethering homotypic fusion and vacuole protein sorting (HOPS) comp
122 lysosome fusion in a manner dependent on the homotypic fusion and vacuole protein sorting (HOPS) teth
123 (SNAREs), that catalyze membrane fusion, and homotypic fusion and vacuole protein sorting (HOPS), tha
125 phate (PI3P) and the tethering complex HOPS (homotypic fusion and vacuole protein sorting complex), w
127 he yeast vacuolar tethering/SM complex HOPS (homotypic fusion and vacuole protein sorting) increases
128 C core vacuole/endosome tethering) and HOPS (homotypic fusion and vacuole protein sorting) tethering
129 m yeast vacuoles including SNAREs, the HOPS (homotypic fusion and vacuole protein sorting) tethering
131 ctures of Vps33, the SM subunit of the yeast homotypic fusion and vacuole protein-sorting (HOPS) comp
136 VE3 (RHD3) is an atlastin GTPase involved in homotypic fusion of endoplasmic reticulum (ER) tubules i
138 coding the atlastin-1 GTPase, which mediates homotypic fusion of ER tubules to form the polygonal ER
139 eatment, a process that is paralleled by the homotypic fusion of granules and their heterotypic fusio
140 ces Chlamydia pathogenicity by promoting the homotypic fusion of inclusions and shares structural and
143 1 that implicates the SNARE protein VTI11 in homotypic fusion of protein storage and lytic vacuoles.
144 autophagosomal machinery to CCVs for optimal homotypic fusion of the Coxiella-containing compartments
146 Like other intracellular fusion events, the homotypic fusion of yeast vacuoles requires a Rab GTPase
149 lar compound events (i.e. granule-to-granule homotypic fusion) was severely reduced in the absence of
156 or Arl8 (Arf-like GTPase 8) and its effector homotypic fusion/vacuole protein sorting complex (HOPS)
157 axon terminals form two independent sets of homotypic gap junctions, a feature which might be import
158 uggest that an essential interaction between homotypic gD and gH/gL occurs during both HSV-1 and SaHV
159 rom mice cultured on astrocyte islands with "homotypic" glutamatergic or GABAergic pairs and autaptic
161 hocytic activation molecule (SLAM) family of homotypic haematopoietic cell-specific receptors, we det
162 ads to acute illness and results in lifelong homotypic immunity, but individuals remain susceptible t
163 leads to acute illness followed by lifelong homotypic immunity, but susceptibility to infection by t
164 virus 1 (HSV1) UL39-encoded ICP6 blocks RIP homotypic interacting motif (RHIM) signal transduction,
165 amiana, we define multiple sites of N domain homotypic interaction and infer that it forms a parallel
168 o suppress TNF-induced necrosis, and its RIP homotypic interaction motif (RHIM) domain was required t
169 ix (Z-form) and receptor-interacting protein homotypic interaction motif (RHIM) domains for protein h
170 nifested this function by binding to the RIP homotypic interaction motif (RHIM) domains of TRIF and R
171 F, the four mammalian proteins harboring RIP homotypic interaction motif (RHIM) domains, are key comp
174 ell death pathway requires an N-terminal RIP homotypic interaction motif (RHIM) within R1, acting in
175 ain a motif with some resemblance to the RIP Homotypic Interaction Motif (RHIM), a domain found in ma
176 RIPK1 deficiency, or mutation of its RIP homotypic interaction motif (RHIM), triggers ZBP1-depend
178 t apoptosis together with competitors of RIP homotypic interaction motif (RHIM)-dependent signal tran
179 perinatal lethality in mice in which the RIP homotypic interaction motif domain of RIPK1 has been mut
180 activates programmed necrosis through a RIP homotypic interaction motif-dependent association of TRI
182 to RHIM [receptor-interacting protein (RIP) homotypic interaction motif], an amyloid motif regulatin
183 t contain receptor-interacting protein (RIP) homotypic interaction motifs (RHIM) play a key role in c
184 , located in the SEFIR domain, abolished the homotypic interaction of ACT1 with IL-17 receptors, with
188 separate alpha121 and alpha345 networks by a homotypic interaction through their trimeric noncollagen
189 rt a model in which WRM-1, which can undergo homotypic interaction, binds LIT-1 and thereby generates
191 To define the gH and gL requirements for homotypic interaction, we evaluated the function of a pa
194 connect with prospective glomeruli based on homotypic interactions among neurons expressing the same
195 l tether between the two organelles, forming homotypic interactions and heterocomplexes with its homo
196 smic domain of atlastin acts as a tether and homotypic interactions are timed by GTP binding and hydr
197 previously observed to mediate nectin/nectin homotypic interactions as well as TIGIT/necl-5 recogniti
198 ns initiate intracellular signalling through homotypic interactions between epitopes that are specifi
200 The phenotypes indicate that these promote homotypic interactions between melanophores and xanthoph
201 double-positive thymocytes that provide key homotypic interactions between signaling lymphocyte acti
202 kably strong adhesion forces by establishing homotypic interactions between single cells, leading to
204 we show that this interaction competes with homotypic interactions between the N termini of differen
206 overlap with an epitope in D4 that mediates homotypic interactions essential for KIT activation.
210 that tau filament ends engage in a range of homotypic interactions involving monomers, oligomers, an
213 e effector caspase-1, which interact through homotypic interactions of caspase recruitment domains (C
214 Moreover, these analyses revealed reversible homotypic interactions of NT5B at low pH and in high cal
216 high structural similarity among them, only homotypic interactions participate in complex formation,
217 a transition in the stiffness of E-cadherin homotypic interactions regulates actin and membrane dyna
218 n to enhance binding to host cells, B domain homotypic interactions support cell accumulation and bio
219 ns between pre-amyloid oligomers prevent the homotypic interactions that would lead to mature amyloid
220 ct mediated by receptor biasing toward ErbB3 homotypic interactions uncommonly formed by native neure
221 d neuronal development, ALCAM undergoes both homotypic interactions with other ALCAM molecules and he
222 chanism whereby UnDOx enables the controlled homotypic interactions within the distal titin spring to
223 Our results indicate that Cox15 exhibits homotypic interactions, forming highly stable complexes
228 JAM-B as the major ligand for JAM-C, whereas homotypic JAM-C interactions remained at background leve
231 e 2 exceeded chance levels (P < .05) for all homotypic (median tetrachoric correlation of rho = 0.54
234 he dynamin superfamily, is known to catalyse homotypic membrane fusion in the smooth endoplasmic reti
236 es nucleotide hydrolysis to the catalysis of homotypic membrane fusion to form a branched endoplasmic
239 protein (GRASP) proteins are Golgi-localized homotypic membrane tethers that organize Golgi stacks in
241 ecific associations for both heterotypic and homotypic motif-pairs with particular haematopoietic cel
244 relation to the spatial positioning of such homotypic neighbors; rather, this cell type modulates th
245 rate a role for NKG2D-ligand interaction via homotypic NK cell contact in NK cell effector function.
246 o, that innate immune NK cells can engage in homotypic NK-to-NK cell interactions for optimal surviva
247 atorial complexity of eight linkage types in homotypic (one chain type per polymer) and heterotypic (
248 the issue of whether the PLAD mediates only homotypic or also heterotypic interactions remained inco
255 EDWI-3 degrades numerous neoblast mRNAs in a homotypic ping-pong cycle, it is also guided to another
256 le of intercellular instructed-assembly from homotypic precursors, this work illustrates a new approa
257 adherin 11, and protocadherin 19) results in homotypic preference ex vivo and patterning robustness i
259 iple mechanisms, including interference with homotypic protein interactions and the selection of the
260 tions that are created through extracellular homotypic protein-protein interactions between cadherin
261 t replicate by recruitment and conversion of homotypic proteins into growing protein aggregates.
264 g a caspase recruitment domain (ASC) through homotypic PYD-PYD interactions and the assembly of an in
265 ocesses, indicating that both connexins form homotypic rather than heterotypic or heteromeric gap jun
267 is thought to result in lifelong immunity to homotypic reinfection (ie, reinfection with the same ser
270 ling has been reported to occur only between homotypic retinal ganglion cells, in line with the conce
271 e propensity for heterotypic peptide-RNA and homotypic RNA LLPS, which results in a switch between co
273 idence is provided for SNAP23 involvement in homotypic SG fusion that occurs in the activated cells.
276 itment of distant T cells through long-range homotypic signalling, in part mediated via the diffusion
277 iases while accounting for the phenomenon of homotypic site clustering commonly observed in developme
279 ed immunity was strongest against completely homotypic strains and weakest against fully heterotypic
280 ne effectiveness, comparing effectiveness of homotypic strains with fully or partly heterotypic strai
281 effectiveness was 94% (95% CI 80-98) against homotypic strains, 71% (39-86) against partly heterotypi
282 accine effectiveness was 83% (78-87) against homotypic strains, 82% (70-89) against single-antigen va
286 trocyte subpopulations selectively regulated homotypic synapses through metabotropic glutamate recept
287 of deMs due to their dominant employment of homotypic TF binding site (TFBS) clusters, as opposed to
292 rocess, we studied fragment formation during homotypic vacuolar lysosome membrane fusion in Saccharom
299 over, the adhesive property occurred in both homotypic with Cx50 expressed in both pairing cells and