ライフサイエンスコーパス: hope

1 of hypothermic oxygenated machine perfusion (HOPE).

2 s to reduce the threat of death and maintain hope.

3 ess towards these goals has been slower than hoped.

4 liminary success of immunotherapy has raised hopes.

5 c origins and opened the door to therapeutic hopes.

6 HOPE 4 was an open, community-based, cluster-randomised

7 This is the first case under the HOPE Act at our center where discovery of an HIV-specifi

8 donors through the HIV Organ Policy Equity (HOPE) Act.

9 ts with high bacterial burdens a therapeutic hope against infection with MDR P. aeruginosa that lack

10 ical successes with gene correction, raising hopes amongst patients and clinicians worldwide.

11 harsh conditions and may activate "incentive hope." An evolutionarily adaptive response to these woul

12 about a patient's future, thereby inspiring hope and encouraging further treatment and 2) an "action

13 tates who have ESKD is often shaped by their hopes and prognostic expectations related to kidney tran

14 after cDCD liver transplantation in 1 Swiss (HOPE) and 6 French (NRP) centers.

15 1 diabetes represents an autoimmune disease, hope arose that immune-based therapies would soon emerge

16 We review studies that present hope as a direct or secondary mediator of outcome.

17 forms of adversity; organisms do not need to hope as a subjective feeling, but to behave as if they h

18 serine, an endogenous amino acid, offers new hope as a therapeutic agent for refractory TLE.

19 istory Museums, for example, the blue whale 'Hope' at the Natural History Museum, London.

20 identify and resolve these mistakes and, we hope, avoid them in the future.

21 hout hypothermic oxygenated liver perfusion (HOPE) before transplantation.

22 We argue that hope can be a therapeutic target and review evidence sho

23 ing of comorbid HFpEF and DM improves, it is hoped clinicians will be better equipped to offer effect

24 Grafts in the HOPE cohort were procured from older donors and had long

25 s born preterm, 54.6% were alive with no AYA HOPE comorbidities at the end of follow-up.

26 Health Outcomes and Patient Experience (AYA HOPE) Comorbidity Index, which includes conditions that

27 ere obtained every 30 minutes during 50 dual-HOPE (D-HOPE) procedures.

28 vorable to such extensions because incentive hope denotes an unconscious process capable of working a

29 We hope disease researchers will expand social network anal

30 hich is a testament to the early success and hope engendered by this line of investigation.

31 or different host-parasite systems, which we hope enhances our understanding of how parasites circula

32 t and review evidence showing the effects of hope-enhancing therapies.

33 ge entered the Atlantic via the Cape of Good Hope, establishing colonies in the Mediterranean Sea, an

34 Many commentaries suggest that incentive hope even could help understand phenomena beyond these r

35 subduction interface, the non-rupture of the Hope fault, and slow apparent rupture speed.

36 stimated that patients operated on today may hope for a 30-year survival of >80%.

37 Such a drug would raise the hope for a cure to many P2X7-dependent pathologies, incl

38 eed, inhibitors of invasion and egress offer hope for a desperately needed new drug to combat this ne

39 utic approaches discussed herein provide new hope for AS patients.

40 determinants, and pharmacogenomics comes the hope for better, disease-modifying, or even curative, ph

41 a new era of personalized medicine, offering hope for curative responses in patients with serious ill

42 therapies continue to be developed providing hope for food allergy patients everywhere.

43 or improved diabetes and lipid control fuels hope for future prevention of CVD associated with diabet

44 ening using large chemical libraries provide hope for improvement.

45 Pitted against the hope for improving treatment outcomes is the threat of t

46 patients who seem unresponsive, thus raising hope for more accurate diagnosis and prognosis.

47 Some new developments raise renewed hope for neuroprotection: the appearance of new compound

48 ed progress over the past few years provides hope for new, efficacious opioids devoid of the side eff

49 ties, unique therapeutic options and greater hope for prolonged survival.

50 from a diverse pool of precursors, fostering hope for rapid induction of a protective immune response

51 In vivo regeneration of beta cells provides hope for self-renewal of functional insulin-secreting ce

52 itioning from emergence to endemism, lending hope for the continued survival of the endangered Tasman

53 chine learning provides the first glimmer of hope for the development of an accurate, inexpensive, fa

54 e explored; these efforts provide reasonable hope for the future.

55 r targeted drug therapies, thereby providing hope for the management of patients suffering from this

56 Although most participants hoped for direct benefit, no one expected to benefit.

57 This has raised hopes for applications in data encryption, data storage,

58 altar, close to the shores of Africa, raises hopes for the future recovery of archaic human DNA from

59 ly with knowledgeable partners to obtain the hoped-for benefits and avoid failures.

60 Speed vaccine program, which range from the hoped-for rapid success to a catastrophic adverse influe

61 Lily Safra Hope Foundation and National Institute for Health Resear

62 Society, National Institutes of Health, and Hope Foundation for Cancer Research.

63 loci already identified, to lay out what we hope future analyses may help us understand, both in ter

64 Hypothermic oxygenated perfusion (HOPE) has been shown to protect liver recipients from ac

65 elimination of immunosuppression and, it is hoped, help revitalize the field of intestinal transplan

66 to consideration together with the incentive hope hypothesis: population mobility, animal domesticati

67 ed some considerations on how the "incentive hope" hypothesis could be tested on a human population.

68 is commentary, we discuss how the "incentive hope" hypothesis explains differences in food-wasting be

69 therapies and gene therapies provide renewed hope in advancing efforts toward a sterilizing or functi

70 core-matched recipients CONCLUSION:: NRP and HOPE in cDCD achieved similar post-transplant recipient

71 See also the editorial by Mitsouras and Hope in this issue.

72 Positioning "incentive hope" in a general model of behavioral control systems r

73 strategy has not been as widely realized as hoped, in part owing to legal and regulatory barriers.

74 Hope is a contextual term that has different connotation

75 We posit that an individual's level of hope is often determined by innate personality character

76 Our hope is that by following our guidelines, researchers wi

77 By summarizing the issues, the hope is that commercial companies, regulatory agencies,

78 The hope is that integrating knowledge of how bone marrow ni

79 The hope is that recognition of paracrine and circadian fact

80 Our hope is that such mechanistic insights will provide a fo

81 Our hope is that the TRPA1 KO rat will become a useful tool

82 By focusing on success stories, the hope is that this Perspective will identify and inform b

83 Our hope is that this technique can form the basis for futur

84 The hope is that with increased awareness of effective curat

85 The hope is that, contained within the mathematical foundati

86 Our hope is to be a part of a solution and provide insight t

87 With each of these iterations, the hope is to ultimately shift away from a one-size-fits-al

88 icle proposes that a new concept - incentive hope - is necessary in the behavioral sciences to explai

89 olinium catalysts in organocatalysis, and we hope it will aid the design of new halogen bond catalyst

90 tivity to the local curvature, from which we hope it will enable new opportunities for designing next

91 e disease originates and progresses will, we hope, lead to new therapies.

92 Specifically, incentive hope may involve mechanisms of anticipation of both rewa

93 amic preservation strategies such as NRP and HOPE may offer safer use of cDCD grafts.

94 disease and, on a personal level, what they hope might be achieved with this information.

95 We hope new research directions based on a molecular approa

96 ystrophy and spinal muscular atrophy, offers hope not only for additional neuromuscular diseases, but

97 have complemented field observations in the hope of achieving a better understanding of the fate and

98 ligand 17 (CCL17) chemokine axis, offer the hope of better results but require clinical validation.

99 gh affinities and selectivities, raising the hope of biomedical applications in the near future.

100 that distinguishes the two ensembles in the hope of clarifying the fuzzy borders of the current clas

101 a matrix, framework or nanoparticle with the hope of constricting the movement of the enzyme and shie

102 tiparametric risk assessment in DCM with the hope of creating parametric risk models to predict sudde

103 nce management, that shaped my career in the hope of demonstrating that career paths and collaboratio

104 n to kill millions of enemy civilians in the hope of ending a ground war that threatens thousands of

105 onalized medicine in psychiatry provides the hope of escape from the current standard trial-and-error

106 me-based therapeutic interventions, with the hope of expanding immunotherapy efficacy.

107 ctors responsible for this success, with the hope of facilitating the development of laboratories in

108 The hope of finding new therapeutic strategies aimed specifi

109 al differences in stress responses, with the hope of harnessing this information for the development

110 studies and flag specific limitations in the hope of helping researchers to make the most of neuroima

111 In the hope of identifying a reliable correlate by comparing pr

112 ntiation, persistence, and function with the hope of identifying novel therapeutic targets to treat,

113 rties of hits and leads are presented in the hope of informing best practices for FBDD.

114 t to blunt immunosuppression in GBM with the hope of maximizing the clinical outcome of antitumor the

115 owever, attempts to target the MMPs with the hope of treating tumors have thus far failed.

116 s and weaknesses in this literature with the hope of triggering further theoretical and empirical dev

117 tractably measure and analyze them with the hope of ultimately facilitating knowledge production and

118 and participation to improve our science in hopes of equitably improving public health.

119 ndations to both students and faculty in the hopes of helping future generations succeed in the field

120 hasize the need for appropriate treatment in hopes of minimizing the progression to invasive disease.

121 hly fluorinated alternatives are produced in hopes of reducing bioaccumulation.

122 Here we investigate the impact of HOPE on the T cell-mediated immune response following ki

123 Overall, we hope our analytical insights on interfacial mechanisms w

124 Finally, we hope our multivariate model and its associated validatio

125 We hope our work will serve a small part in upgrading the R

126 ined every 30 minutes during 50 dual-HOPE (D-HOPE) procedures.

127 Incentive hope refers to a specific motivational mechanism in the

128 While hope remains that earlier intervention with existing the

129 liver grafts were transplanted after NRP and HOPE, respectively.

130 and 95% versus 93% (P = 0.482) after NRP and HOPE, respectively.

131 hypothermic oxygenated machine perfusion ([D]HOPE) resuscitates livers after cold storage, NMP enable

132 A study on Hope's bone surface was performed to assess the biodeter

133 Hence we hope SREF will be a promising tool to study intracellula

134 We hope such information can highlight areas for targeted i

135 We hope that a defined model for NK cell memory will empowe

136 have occurred in the past 4 years, restoring hope that a new era has dawned in oligonucleotide/siRNA

137 However, the initial hope that a small set of genes would be responsible for

138 reports and ongoing clinical trials provide hope that available immunomodulatory therapies could hav

139 We hope that both newcomers and specialists will benefit fr

140 s but Goodies classic reading list, with the hope that by looking back at highlights in the field of

141 It is my hope that by sharing snippets of my journey, enriched as

142 y across the United States and elsewhere, we hope that early experiences from a heart team operating

143 There is hope that functional magnetic resonance imaging (fMRI) f

144 autoimmune T cell-mediated disease provides hope that future therapies directed towards depleting th

145 sion patterns on drug sensitivity, providing hope that future treatment options will become increasin

146 lity of data at public archives provides the hope that greater insights could be obtained through int

147 We hope that identifying the molecular cues regulating each

148 enetic association studies (GWAS) raised the hope that it would be possible to identify single polymo

149 I especially hope that my trajectory will be of interest and perhaps

150 nd offering future avenues for discovery, we hope that others also embrace the comparative approach t

151 We hope that our approach will be applicable to many biolog

152 More broadly, we hope that our approach will provide the blueprints for n

153 We hope that our review and perspectives provide rationales

154 We hope that our review article may serve as a reference po

155 Early warning signals (EWSs) offer the hope that patterns observed in data can predict the futu

156 iple sclerosis, but there is a real sense of hope that researchers are getting closer to a successful

157 These data not only raise the hope that researchers working in drug discovery may be a

158 cientific rationale for this approach in the hope that researchers, regulators, funders and editors c

159 Here I reflect on my encounter, in the hope that sharing it can be of some value.

160 lytic functions of active kinases, providing hope that similar properties in pseudokinases could be p

161 We hope that some of these innovations, hard-gained in this

162 We hope that such implementation of a pool test for coronav

163 We hope that the adoption of STing will help to democratize

164 We hope that the conceptual framework proposed in this revi

165 We hope that the creation of this ecosystem will allow agen

166 est practices in undergraduate education and hope that the dissemination of this declaration will pla

167 It is our hope that the emerging big picture of the formation and

168 ts and materials scientists and to give them hope that the field of molecular semiconductors for logi

169 We hope that the framework will be helpful to validate othe

170 We hope that the quantified series could serve as a textboo

171 It is our hope that the strategy of temperature cycling to "freeze

172 th venous thromboembolism (VTE), the initial hope that their presence would inform recurrence risk an

173 cannot be sustained for the long term in the hope that there will be an effective vaccine or treatmen

174 There is hope that these advances will be helpful in treating mor

175 We hope that these findings will lead to the synthesis of o

176 We hope that these initial advances will encourage basic sc

177 We hope that these recommendations will help researchers to

178 These materials are freely shared, with the hope that they become part of a pool of open-source soft

179 ts and resources for this undertaking in the hope that they may enhance the experience of others.

180 m George in honor of his memory and with the hope that they may inspire future generations of scienti

181 the field of livestock helminthology, and we hope that they will stimulate ongoing or new research ef

182 We hope that this algorithm can support diagnostic decision

183 We hope that this approach will offer a simpler, more robus

184 We also hope that this article can serve as a resource that will

185 We hope that this comprehensive review attracts more plant

186 We hope that this comprehensive survey and the proposed str

187 We hope that this contribution highlighting the generalizab

188 antioselectivity in radical reactions and we hope that this focused survey of progress so far will in

189 We hope that this framework contributes to a balanced appro

190 an example of excellent preservation, and we hope that this manuscript will be a starting point for m

191 opment of a stronger evidence base, with the hope that this paper serves as a catalyst for a renewed

192 We hope that this Perspective, together with other similar

193 We hope that this platform, which is compatible with a larg

194 We hope that this review article offers the impetus and roa

195 Therefore, we hope that this review will help to better understand the

196 te and our knowledge is evolving rapidly, we hope that this review will provide a useful framework an

197 d examples of biological applications in the hope that this snapshot of a new but quickly developing

198 We hope that this will help future studies to further chara

199 We hope that this work inspires experimental studies on the

200 s of more-complex natural communities and we hope that this work will help to bridge the gap between

201 We hope that this work will provide a common vocabulary tha

202 We hope that, in the same way that linear DNA became a cano

203 Initially, it was hoped that accurate measurement of behavioural phenotype

204 It is hoped that further development of this inverse approach

205 defining challenges for drug hunters, it is hoped that further research into the medicinal chemistry

206 It is hoped that his proof-of-concept device with machine-lear

207 ng a deeper understanding of the KCCQ, it is hoped that its use can further improve the patient-cente

208 It is hoped that our manuscript can serve to spur greater fede

209 It is hoped that quiescent NSCs could be activated therapeutic

210 It is hoped that the approach of computing partition ratios of

211 It is hoped that the definitions and considerations described

212 It is hoped that the present work will inspire the development

213 It is hoped that the research in this review can provide a ref

214 It is hoped that these scales will be used for future research

215 It is hoped that this account will stimulate ideas that transc

216 It is hoped that this analysis will aid the development of fut

217 It is hoped that this contribution will be supportive of the f

218 It is hoped that this Perspective will inspire the chemist to

219 It is hoped that this review will encourage scientists and aca

220 It is hoped that this review will not only deepen the ties bet

221 pursuit of novel MRI contrast agents, it is hoped that this review will spur the critical thinking f

222 middle-income countries (LMICs) have raised hopes that artificial intelligence (AI) might help to ad

223 Initial hopes that these abnormalities of REM sleep may serve as

224 article is to report our Society's plans in hopes that we may stimulate other scientific societies t

225 ey personal exposure data for this study, we hope the application and learnings from our exposure ass

226 We hope the discussion on this intriguing scenario will pro

227 We hope the findings will inform the debate about the role

228 We hope the results of this study will inform key areas of

229 derrepresented state of women in science, we hope these guidelines may be adapted and applied to grou

230 We hope these numbers add context as policy makers establis

231 We hope these recommendations can provide guidance to advoc

232 We hope these results will encourage journals, institutions

233 We hope these results will provide insight into the rationa

234 cacy are needed to turn the "hype" into the "hope" these new-age oncology therapeutics have to offer.

235 We hope this discussion will contribute to potential future

236 We hope this discussion will provide a framework for instit

237 We hope this effort will foster ongoing dialog and promote

238 We hope this form of display along with the added annotatio

239 of therapeutic and genomic developments, we hope this inflammation-profiling approach will enable fu

240 In sum, we hope this novel parcellation algorithm will facilitate f

241 istorically been underrepresented at SER; we hope this program continues to grow in its reach and imp

242 We hope this review facilitates some of these interactions

243 We hope this summary will serve not only as a timeline and

244 Going forward, we hope this will help provide support to individuals in th

245 We hope this will provide further reproducibility, robustne

246 We are hoping this review could inspire further researches in d

247 potentially automate radiation dosimetry we hope to accelerate the understanding of radiobiology and

248 potentially automate radiation dosimetry, we hope to accelerate the understanding of radiobiology and

249 In writing this essay, I hope to achieve three aims: 1) to tell the story of how

250 Given the potential for hope to alter oncological outcomes in patients with canc

251 Lastly, we hope to bring further insights into the synthesis of int

252 Hence, we hope to bring new perspectives to alleviate the metaflam

253 By presenting this case, the authors hope to bring renewed attention to this phenomenon among

254 We hope to cast some doubt on this assumption and instead a

255 t good starting points for self-learning and hope to convince readers that computational data analysi

256 methods based on bioorthogonal reactions, we hope to enable researchers to interrogate the mechanics

257 recruit and support minority applicants, we hope to encourage more students to consider the MD/PhD c

258 In this way, we hope to illustrate how bacteria have evolved common appr

259 We hope to increase research and policy attention on these

260 ndicus and two different types of viruses we hope to increase the understanding of virus-host interac

261 American Heart Association to combat RHD, we hope to inspire others to collaborate, communicate, and

262 Here we review what is known and what we hope to learn about how bacteria and the factors they pr

263 is via the R packages R-INLA and glmmTMB, we hope to make efficient estimation of RSFs and SSFs with

264 In this work, we hope to make it easier for readers to find relevant rese

265 immunomodulatory therapies has given renewed hope to many patients, but notable challenges remain wit

266 In doing so, we hope to motivate increased investigation of the temporal

267 We hope to offer rational solutions to overcome some major

268 nagement of malignant melanoma and now offer hope to patients with advanced disease.

269 ystems and novel surgical interventions give hope to patients with PD about their future outcomes and

270 Immunotherapy is bringing new hope to patients, but also a whole new spectrum of toxic

271 standard-of-care approaches and bringing new hope to patients.

272 In doing so, we hope to provide a common framework that will facilitate

273 ring some of the lessons learned by CIRM, we hope to provide insights into concrete improvements that

274 By disclosing these compounds, we hope to provide valuable tools for the study of PTK2 deg

275 ar border between facts and speculations, we hope to stimulate the future research toward a better un

276 potential to meet the TPP specifications, we hope to support harmonized evidence generation and enabl

277 These findings are hoped to assist in further manipulation and metabolic en

278 dimensional (3D) culture systems have fueled hopes to bring about the next generation of more physiol

279 This study hopes to provide a new design concept for high-performan

280 achieved a sterile cure, with millions more hoping to avoid the potential pitfalls of lifelong antir

281 view charts future perspectives in the field hoping to encourage further progress and applications, w

282 s reflect on their paths to IDSA leadership, hoping to help guide members seeking to partner with the

283 act as a resource for microbiome researchers hoping to identify host effects of microbiome colonizati

284 ers were not significantly different between HOPE-treated DCD and unperfused DBD liver recipients at

285 /70) recipients with tumor recurrence in the HOPE-treated DCD cohort (P = 0.002) in Center A.

286 Additionally, HOPE-treated kidneys showed better function and less ear

287 Our series includes 100 HOPE-treated liver-transplanted patients with an overall

288 Similarly, HOPE treatment protected recipients of extended donation

289 Similarly, HOPE treatment, without any immunosuppression, protected

290 HOPE-treatment of DCD livers resulted therefore in a 5-y

291 How can we make this hope true more often, for more of the clients who need o

292 a whole spectrum of diseases-an analysis we hope will be helpful in weighing the risks and benefits

293 okinetics characterize these tools, which we hope will be of broad utility to the field of epigenetic

294 tion, including an illustrated key, which we hope will improve the diagnostic capabilities of hematol

295 unexpected positives that we have found and hope will persist: improved access to experts; deeper an

296 ssay, I share bits of my life's story that I hope will resonate with a broad audience, especially stu

297 comprehensive overview of cyclotides that we hope will stimulate further work on this fascinating fam

298 n extensive overview of gas hydrates that we hope will stimulate further work on this riveting field.

299 vide suggestions for future research that we hope will yield important information for the developmen

300 We analyse the concept of hope with respect to its applicability for oncology.