ライフサイエンスコーパス: horn

1 ation co-localized to the ipsilateral dorsal horn.

2 cated in lamina II of the superficial dorsal horn.

3 vity across all laminae of the spinal dorsal horn.

4 ding capability of the mechanosensory dorsal horn.

5 ate afferent input to the superficial dorsal horn.

6 ons (MBONs) connecting the MB to the lateral horn.

7 n superficial laminae of the thoracic dorsal horn.

8 ferent synapses from the spinal cord ventral horn.

9 itory interneurons in the spinal cord dorsal horn.

10 icking the collagenous component of the real horn.

11 ds by gating mechanical inputs in the dorsal horn.

12 elated peptide (CGRP) staining in the dorsal horn.

13 c transmission within the superficial dorsal horn.

14 these cells in the superficial spinal dorsal horn.

15 ng to a decision neuron (LHN) in the lateral horn.

16 a membranes (SPMs) of the ipsilateral dorsal horn.

17 CaV2.2 expression in the SPMs of the dorsal horn.

18 n neurons in the spinal and medullary dorsal horn.

19 ctivity to the mushroom body and the lateral horn.

20 of double labeling in the superficial dorsal horn.

21 -facilitated CaV2.2 expression in the dorsal horn.

22 dorsal root ganglia (DRG) and spinal dorsal horn.

23 ding projection neurons in the spinal dorsal horn.

24 r labeled S1 CST terminals within the dorsal horn.

25 al circuitry, particularly within the dorsal horn.

26 with enhanced activity of the spinal dorsal horn.

27 xcitatory interneurons in superficial dorsal horn.

28 y interneurons in the rat superficial dorsal horn.

29 ts that the CSDns receive within the lateral horn.

30 ciceptive A-delta and C fibers in the dorsal horn.

31 lia and spinal sensory input from the dorsal horn.

32 ypes (A vs. C fibers) across thoracic dorsal horns.

33 properties between the natural and the faux horns.

34 nd both labels were quantified in the dorsal horns.

35 soventrally expanded mandibles and elaborate horns.

36 descending projections to the spinal dorsal horn [1].

37 s, forceps, proboscises, stingers, tusks and horns [1].

38 verlapping region of the reorganizing dorsal horn; (2) S1 CST and primary afferent inputs connect in

39 tic spine dynamics in the superficial dorsal horn; (2) that nerve injury-induced pain triggers change

40 d II neurons within the rodent spinal dorsal horn, a principal site of action for opiate analgesia.

41 cal techniques has revealed that the lateral horn, a region of the brain involved in olfaction in fli

42 rge and unique repertoire identified in head horns, a recent morphological innovation.

43 outed in an overlapping region of the dorsal horn after injury, and that larger (presumably faster) c

44 through its functional resemblance to an ear horn (aka ear trumpet), the geometry of the cochlear duc

45 esent in lamina II of the superficial dorsal horn, an area involved in nociception.

46 ts, in the developmental evolution of beetle horns, an evolutionary novelty, and horn polyphenisms, a

47 gical evidence of reconnection to the dorsal horn and behavioral recovery in mechanical pressure, the

48 in laminae I and V of the spinal cord dorsal horn and caudal spinal trigeminal nucleus and in the nuc

49 onally transported to the spinal cord dorsal horn and contributes to characteristics of neuropathic p

50 ents, which terminate medially in the dorsal horn and dorsolaterally in nTTD, terminate in specific c

51 to higher brain areas including the lateral horn and mushroom body.

52 annels, were inserted into the lumbar dorsal horn and peripheral neurons activated electrically via t

53 lbumin-expressing interneurons in the dorsal horn and represents a pharmacological target to manipula

54 tic tracing of genetically identified dorsal horn and RVM neurons to uncover an RVM-spinal cord-prima

55 Hz) frequency oscillations within the dorsal horn and somatosensory thalamus.

56 Crossings were detected in areas of dorsal horns and anterior white commissure.

57 JCI, Vella et al. have taken the bull by the horns and applied considerable technical muscle to answe

58 Comparative analyses reveal that bovid horns and cervid antlers share similar gene expression p

59 in the lower cranial nerve nuclei, anterior horns and corresponding nerves, atrophy of the spinothal

60 iate the serial homology between prothoracic horns and insects wings and suggest that other insect in

61 The calves had no horns and were otherwise healthy and phenotypically unre

62 These include loss of lower (ventral horn) and upper motor neurons (corticospinal motor neuro

63 n are normally balanced in the spinal dorsal horn, and how their imbalance disrupts somatosensory pro

64 al correlations in the ventral horns, dorsal horns, and central spinal cord gray matter.

65 ady-state behavior in the spinal cord dorsal horn; and (3) this work opens the door to further invest

66 e beam when the lens is applied to a conical horn antenna.

67 dels in which afferent inputs in the ventral horn are dramatically reduced (ER81(-/-) knockout), weak

68 The horns are assembled from repeated globular domains attac

69 Horns are sexually selected traits used in contests betw

70 rature active hydrothermal venting at Dragon Horn area (49.7 degrees E) on the Southwest Indian Ridge

71 was injected into the left intermediolateral horn around the thoracolumbar junction, whereas a Cre-de

72 es in dendritic spine dynamics in the dorsal horn associated with peripheral nerve injury and pain.

73 ch it mediates sex-specific development in a horned beetle species by combining systemic dsx knockdow

74 conserved during development of Onthophagus horned beetles and have retained the ability to regulate

75 cription in three closely related species of horned beetles exhibiting strikingly diverse degrees of

76 Within the dorsal horn, besides KChIP3 in the inner lamina II and lamina I

77 ered, approximately 120,000-y-old giant long-horned bison, Bison latifrons, from Snowmass, Colorado.

78 ibition and returns a highly derived sigmoid horn body size allometry to its presumed ancestral, line

79 isbudding, a routine procedure that prevents horn bud growth through cauterization, is painful for ca

80 CST terminal boutons in the affected dorsal horn, but no change in the size profile of the spared/sp

81 s between dentate gyrus (DG) and the Ammon's horn (CA1) within the hippocampus.

82 ia and reduced CGRP expression in the dorsal horn caudal to the lesion.

83 motor nerve up to the level of the anterior horn cell.

84 lei and in the neuropil surrounding anterior horn cells.

85 ern: a symmetric involvement of the anterior horn cells.

86 ediated through at least two distinct dorsal horn circuit mechanisms.

87 To determine how dorsal horn circuitry alters to facilitate recovery post-injury

88 MGE-derived neuronal precursors into dorsal horn circuitry in intact, adult mice with short- (5-6 we

89 Little is understood about dorsal horn circuitry, despite the fact that this region loses

90 Prostephanus truncatus (Horn) (Coleoptera: Bostrichidae), is a beetle that is a

91 -opioid receptors (MOR) in the spinal dorsal horn constitutively repress the expression of synaptic l

92 rabrachial neurons in the superficial dorsal horn contribute to persistent pain states, and that the

93 enhancing glycinergic tone within the dorsal horn could obtund nociceptor signaling to the brain and

94 the dominant P(C) Celtic POLLED allele, with horned cows (pp) and obtained six heterozygous (P(C)p) p

95 In the lateral horn, CSDn processes are excited in an odor identity dep

96 throughout the superficial and deeper dorsal horn (DDH), as well as the lateral spinal nucleus (LSN),

97 We show that prothoracic horns derive from bilateral source tissues; that diverse

98 n the trypanotolerant N'Dama, coat color and horn development in Ankole, and heat tolerance and tick

99 gonize each other through spinal cord dorsal horn (DH) gating neurons.

100 The dorsal horn (DH) of the spinal cord is a complex laminar struct

101 ABSTRACT: The dorsal horn (DH) of the spinal cord is an important site for mo

102 es changes in sensory circuits of the dorsal horn (DH) where nociceptive inputs integrate for pain pr

103 of painful stimulation occurs in the dorsal horn (DH), an area of the spinal cord that receives inpu

104 regions of the CNS, including in the dorsal horn (DH), its contribution to pain remains undefined.

105 Using DRG and dorsal horn (DH; another key structure for CIPN pain response)

106 tract, spinal trigeminal nucleus, and dorsal horn [DH]).

107 conveying mechanical allodynia in the dorsal horn differ by the nature of the injury.

108 , the transcriptional profile of prothoracic horns diverges markedly from that of wings and other win

109 d intersegmental correlations in the ventral horns, dorsal horns, and central spinal cord gray matter

110 Thus, based on the changes in dorsal horn, DRG and peripheral innervation, we suggest that th

111 ncore stores 3 x more strain energy than the horn during impact.

112 How interneurons (INs) in the dorsal horn encode these modalities and transform them into sti

113 ilitate mechanical pain by inhibiting dorsal horn enkephalinergic/GABAergic interneurons.

114 sue of the Journal of Clinical Microbiology, Horn et al. (E.

115 Dorsal horn excitatory interneurons that express gastrin-releas

116 Functional connectivity of dorsal horns exhibited a U-shaped profile along the dorsal-inte

117 ng infection, Il1a(-/-) oviducts and uterine horns exhibited reduced neutrophil infiltration, and thi

118 ed equivalent hyperalgesia and spinal dorsal horn expression of genes associated with microglial prol

119 Fluralaner shows promise for control of horn flies and house flies.

120 Insecticide-susceptible horn flies and stable flies were tested topically.

121 outperformed permethrin by > 2-fold for the horn flies but underperformed permethrin by > 45-fold fo

122 d thereby regulates weapon size in the broad-horned flour beetle Gnatocerus cornutus.

123 We therefore seek a new surface, the horn, for which a defect-free state can be maintained fo

124 of horn polyphenisms by actively suppressing horn formation in low-nutrition males.

125 South American horned frogs (Ceratophrys) are a notable exception.

126 the superficial medullary and spinal dorsal horn from the trigeminal subnucleus caudalis to C2.

127 characterised by the separation of the hoof horn from the underlying skin.

128 al pain likely via modulation of deep dorsal horn GABAergic neurons.SIGNIFICANCE STATEMENT Pain is th

129 er the evolution trail was flower-like gall, horned gall, circular gall and ensiform gall.

130 urther support for a critical role of dorsal horn gastrin-releasing peptide neurons in itch circuits,

131 a role in pain.SIGNIFICANCE STATEMENT Dorsal horn gastrin-releasing peptide neurons serve a well-esta

132 neurotransmission in the spinal cord dorsal horn gates nociceptive signaling, is essential in mainta

133 n, horn length, and testes size, but not for horn growth or our measure of annual fitness.

134 nd leg length, parasite burden, horn length, horn growth, and testicular circumference.

135 population density for all traits apart from horn growth, with directional selection being stronger u

136 These data confirm a critical role of dorsal horn GRP neurons in spinal itch transmission but do not

137 uitry for mechanical allodynia in the dorsal horn has important implications for the mechanistic and

138 erated cranial structures such as crests and horns, hereafter referred to collectively as ornaments,

139 or D1 in synaptic compartment (P3) in dorsal horn homogenates and presynaptic met-enkephalin-containi

140 mmunoreactivity for met-enkephalin in dorsal horn homogenates, which was dose-dependently attenuated

141 ptured other arthropods between mandible and horn in a manner that could only be achieved by articula

142 that were confusingly similar to real rhino horn in look, feel and properties.

143 nges to the neuronal circuitry of the dorsal horn in monkeys following a lesion that deafferented thr

144 pinal injection targeting the lumbar ventral horn in rodents.

145 uperficial laminae of the spinal cord dorsal horn in TOW mice, specifically in GABAergic inhibitory n

146 We investigated the origin of prothoracic horns in scarabaeine beetles, one of the most pronounced

147 o 19 min of asphyxia by immersing the uterus horns in water at 37 degrees C followed by 30 min in air

148 s, and microglia activation in spinal dorsal horns in wild-type mice, but all these changes were comp

149 ration underlies normalization of the dorsal horn inhibitory tone after injury and may be responsible

150 ined to delineate specific changes to dorsal horn input circuitry.

151 er expressed by a small population of dorsal horn interneurons (GRP neurons).

152 nclude that Y1R-expressing excitatory dorsal horn interneurons facilitate neuropathic pain hypersensi

153 ) in the most cranial portion of the uterine horn ipsilateral to the corpus luteum.

154 ulated excitability within the spinal dorsal horn is a critical mediator of chronic pain.

155 The spinal dorsal horn is a major site for the induction and maintenance o

156 The deep dorsal horn is a poorly characterized spinal cord region implic

157 Demand for rhino horn is driving poaching with devastating effect for the

158 We demonstrate that the dorsal horn is organized into spatially restricted excitatory m

159 profiles within the Vc/C2 superficial dorsal horn (lamina I) 3 weeks post-CCI-ION.

160 nes over time on the same superficial dorsal horn (lamina II) neurons before and after peripheral ner

161 Activity mapping suggested dorsal horn laminae II-IV was activated in females but showed n

162 sacral parasympathetic nucleus (SPN), dorsal horn laminae II-IV, and dorsal commissural nucleus (SDCo

163 CK) neurons located deeper within the dorsal horn (laminae III-IV) are important for both types of in

164 trade-off when investing in testes mass vs. horn length between the species.

165 Male horn length consistently experienced positive sexual sel

166 ale ('soft selection'), whereas selection on horn length occurred at the metapopulation scale ('hard

167 We compared relative pronotal horn length using high-resolution X-ray CT scanning data

168 or body weight, leg length, parasite burden, horn length, and testes size, but not for horn growth or

169 dy weight, hind leg length, parasite burden, horn length, horn growth, and testicular circumference.

170 he mushroom body (CA) as well as the lateral horn (LH) of the protocerebrum via the medial AL tract.

171 la, one higher olfactory centre, the lateral horn (LH), is implicated in innate behaviour.

172 body, required for learning, and the lateral horn (LH), proposed to mediate innate olfactory behavior

173 single pair of Lk neurons within the Lateral Horn (LHLK neurons).

174 ke mouthparts along with a striking array of horn-like cephalic projections [4-6].

175 present a general acoustic treatment of the horn-like geometry of the cochlea, accompanied by a simp

176 nal membrane vesicle whilst 2-fold symmetric horn-like structures protrude outwards.

177 The Texas Horned Lizard (Phrynosoma cornutum) is native to the wes

178 ronal components and functions of the dorsal horn LTMR-recipient zone (LTMR-RZ), a role for LTMR-RZ p

179 In dorsal horn, males and females show increased GFAP(+) astrocyti

180 tive hornless tortoise, unlike the Gondwanan horned meiolaniid radiation to the southwest.

181 Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a signif

182 toneurons, where it was required for ventral horn microglial activation and proliferation.

183 ed axonal and synaptic plasticity on ventral horn motor neurons.

184 issecting the cellular composition of dorsal-horn networks, studies are beginning to elucidate the in

185 e develop a mathematical model of the dorsal horn neural circuit to investigate mechanisms for the da

186 Here we show that in spinal dorsal horn neurons >80% of mGluR5 is intracellular, of which a

187 ptional changes in superficial spinal dorsal horn neurons (SSDHN) are essential in the development an

188 ncrease in c-Fos expression in spinal dorsal horn neurons and displayed increased evoked activity and

189 oded by Tacr1) is expressed in spinal dorsal horn neurons and has been suggested to mediate itch in r

190 than 20% of superficial Tacr1(CreER) dorsal horn neurons are spinal projection neurons, and thus the

191 hyperexcitability of nociceptive deep dorsal horn neurons by TNF-alpha largely depends on the formati

192 To characterize the subtypes of dorsal horn neurons engaged by dopamine signaling in the hypera

193 of glycine-activated current in mouse dorsal horn neurons from spinal cord slices.

194 nd central sensitization of medullary dorsal horn neurons is a critical factor in muscle hyperalgesia

195 cordings from mechanonociceptive deep dorsal horn neurons of normal rats in vivo, we found that spina

196 ing the Wnt5a-Ryk/Ror2 axis in spinal dorsal horn neurons prevented activity-dependent dendritic spin

197 othing is known about how superficial dorsal horn neurons process sensory input from muscle versus sk

198 in synapses, such as those on anterior motor horn neurons that integrate many complex neural inputs.

199 ity of second-order trigeminovascular dorsal horn neurons that receive peripheral input from the cran

200 induces ROS production in spinal cord dorsal horn neurons, an effect eliminated by ROS scavenger N-te

201 uli activate overlapping ensembles of dorsal horn neurons, and that stimulus type and intensity is en

202 d neurons, but not wide dynamic-range dorsal horn neurons, and why it may not be effective in all mig

203 , along with moderate (47%) loss of anterior horn neurons, notably in demyelinating MS lesions.

204 primary afferents and in superficial dorsal horn neurons, there is little to no information as to th

205 tween dorsal root ganglia neurons and dorsal horn neurons, we reconstructed the first pain synapse in

206 m putative gustatory interneurons or lateral horn neurons, which can also relay indirect feedback fro

207 he resulting synaptic transmission to dorsal horn neurons.

208 inal cord and oxidative DNA damage in dorsal horn neurons.

209 enhanced neuronal responses in spinal dorsal horn neurons.

210 regulated kinase (ERK) in superficial dorsal horn neurons.

211 hyperexcitability of nociceptive deep horsal horn neurons.

212 SCs and puff NMDAR currents in spinal dorsal horn neurons.

213 oot and puff NMDAR currents in spinal dorsal horn neurons.

214 ts receptors at multiple sites in the dorsal horn: NPY Y1 receptors (Y1Rs) on post-synaptic neurons a

215 tients with Ommaya-reservoirs to the frontal horn of a lateral ventricle.

216 frican continent (Algeria and Libya) and the Horn of Africa (Ethiopia).

217 laria was reported from Djibouti City in the Horn of Africa and increasingly severe outbreaks have be

218 clude creation of new protected areas in the horn of Africa and Liberia, as well as improved connecti

219 The Horn of Africa harbors the largest reservoir of Plasmodi

220 oss its full range (Asia, Arabian Peninsula, Horn of Africa) and a set of spatial models that identif

221 uniquely is most frequent in Arabia and the Horn of Africa, but is distributed much more widely, fro

222 We confirm the broad significance of the Horn of Africa, Guinean forests, coastal forests of East

223 ef) is a cornerstone of food security in the Horn of Africa, where it is prized for stress resilience

224 ettii infections are mainly described in the Horn of Africa.

225 s shaped the genome of today's cattle in the Horn of Africa.

226 eneration develops in the spinal cord dorsal horn of HIV patients with chronic pain, but the patients

227 c protein, specifically in the spinal dorsal horn of patients with HIV-1 in whom pain developed, sugg

228 ynapse on second-order neurons in the dorsal horn of subnucleus caudalis and cervical C1/C2 spinal co

229 was preferably expressed within the anterior horn of the gray matter, in both cervical and lumbar sec

230 nt of the spinal cord, targeting the ventral horn of the gray matter.

231 ateral ventricle, distance between occipital horn of the left lateral ventricle and internal surface

232 the nociceptive neurocircuitry of the dorsal horn of the lumbar cord.

233 glia-mediated inflammation within the dorsal horn of the lumbar spinal cord.SIGNIFICANCE STATEMENT Mo

234 y is the die-back in the spinal cord ventral horn of the projections of proprioceptive axons mediatin

235 oglia and astrocyte activation in the dorsal horn of the spinal cord and pain-related brain regions,

236 60 and GPR160 increased in the rodent dorsal horn of the spinal cord following traumatic nerve injury

237 ne-1-phosphate (S1P) generated in the dorsal horn of the spinal cord in response to nerve injury driv

238 neurotransmission in the superficial dorsal horn of the spinal cord is thought to contribute to chro

239 ssed by neuronal circuits in the deep dorsal horn of the spinal cord.

240 the primary synaptic afferents in the dorsal horn of the spinal cord.

241 ulate incoming noxious stimuli in the dorsal horn of the spinal cord.

242 itially integrated in the superficial dorsal horn of the spinal cord.

243 ing dorsal root ganglia (DRG) and the dorsal horn of the spinal cord.

244 pe was counted within the superficial dorsal horn of the Vc/C2 and the means from each rat were compa

245 xcitatory synapses in the superficial dorsal horn of Vc/C2 could lead to enhanced activation of nocic

246 vealed correlated signals in the spinal cord horns of monkeys and humans.

247 ed abundance of the kinase RSK in the dorsal horns of the spinal cord, which are heavily populated wi

248 Synaptic inhibition in the spinal dorsal horn plays a key role in that processing.

249 trait thresholds, such as those involved in horn polyphenisms and the corresponding origin of altern

250 ole in the nutrition-dependent regulation of horn polyphenisms by actively suppressing horn formation

251 f beetle horns, an evolutionary novelty, and horn polyphenisms, a highly derived form of environment-

252 ass, specifically for GfTNMT from the yellow horned poppy (Glaucium flavum).

253 ontests between males, and we find that both horn presence and relative size are strongly positively

254 5a-Ryk/Ror2 interaction in the spinal dorsal horn prevented spine remodeling and significantly reduce

255 at, in the absence of Hox input, prothoracic horn primordia transform to contribute to ectopic wings.

256 However, dorsal horn projection neurons that contribute to the postsynap

257 ., habituation of) an aversive sound (klaxon-horn) reduced freezing to conditioned stimuli previously

258 These are a cephalic horn resulting from an extreme modification of the clype

259 inity anomaly was advected south around Cape Horn, resulting in brief but significant impacts on coas

260 In all cases, one of the uterine horns revealed collection due to a hemivaginal septum an

261 mulate wells from a specific well pad in the Horn River Basin, British Columbia, where there is suffi

262 s upstream pathway in the spinal cord dorsal horn (SCDH).

263 bpopulation of excitatory superficial dorsal horn (SDH) neurons.

264 ity of neurons within the superficial dorsal horn (SDH) of the spinal cord is thought to underlie hei

265 mission within the spinal superficial dorsal horn (SDH) that include a reduction in primary afferent-

266 gic neurons in the mature superficial dorsal horn (SDH), and modifies activity-dependent plasticity a

267 gnaling across the mature superficial dorsal horn (SDH), remains unknown.

268 ers, including the mushroom body and lateral horn, seats of learned and innate behavior.

269 tion of sound, we analyze the effects of the horn-shaped domain, material properties of the tracheal

270 inuous fields of epidermal scales and intact horn sheaths capping the body armor.

271 cal properties of biomaterials such as hair, horn, skin, or bone are determined by the architecture o

272 l, as in other species, into cervical dorsal horn, subnucleus caudalis, subnucleus interpolaris, subn

273 regulate glutamate release at the DRG-dorsal horn synapse.

274 ation of glutamate release at the DRG-dorsal horn synapse.

275 eceptor (NMDAR) responses at lamina I dorsal horn synapses.

276 upregulates phosphorylated GluN2B at dorsal horn synapses.

277 A preferential ability of the dorsal horn synaptic network to amplify nociceptive input arisi

278 gerated sexual traits (for example, antlers, horns, tail feathers, mandibles and dewlaps), show that

279 ers projected to deeper layers of the dorsal horn than did C fibers.

280 afferent terminals in the superficial dorsal horn that co-expressed the neuropeptide CGRP.

281 f neurons in lamina III and IV of the dorsal horn that coexpress PAX2, a transcription factor for GAB

282 in the mouse superficial spinal cord dorsal horn that express estrogen receptor alpha (ERalpha) and

283 inhibition circuit in the spinal cord dorsal horn that processes mechanical itch as well as spontaneo

284 pathway, a region of the sacral spinal cord horn that receives visceral sensory afferents from the b

285 The lateral horn, the insect analog of the mammalian cortical amygda

286 radely labeled axons innervated each uterine horn, these projected rostrally or caudally from their s

287 transferred to the mushroom body and lateral horn through dual pathways termed medial and lateral ant

288 y due to the leakage of LPS from the uterine horns through the cervix.

289 es move from medial to lateral in the dorsal horn to dorsomedial to ventrolateral in nTTD, whereas in

290 t morphological change from unpeeling "ram's horns" to blunt-ended dissociation at the microtubule en

291 ivity in the healthy adult rat spinal dorsal horn via activation of spinal 5-HT3 receptors (5-HT3Rs).

292 tx), the beta-ntx from the venom of the nose-horned viper (Vipera a.

293 n gerbil Gerbillus pyramidum and the Saharan horned viper Cerastes cerastes.

294 After 7-9 days, uterine horns were stained to visualize traced nerve axons and e

295 s differs from GABAA receptors in the dorsal horn, where different receptor stoichiometries underlie

296 els expressed in nerves of the spinal dorsal horn, where their activation is believed to reduce trans

297 or beamline science have focused on Langevin horns which deliver significant power to the confined dr

298 Dns) innervate the antennal lobe and lateral horn, which are first and second order neuropils.

299 right and left lateral ventricle, posterior horn width of the right and left lateral ventricle, dist

300 cant differences with regard to the anterior horn width of the right and left lateral ventricle, post