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1 d in 18% of participants, most commonly with housekeeping (48%) and transportation (36%) and least co
2 ases containing the a3-subunit, but not the "housekeeping" a1-subunit, were isolated bound to actin.
3 f enhanced migratory, vasculoprotective, and housekeeping activities, as well as profound suppression
4 ted without negative effects on the enzyme's housekeeping activity in translation.
5 Using mutagenesis analysis, we separated the housekeeping activity of IRE1alpha at MAMs from its cano
6 onstrates the importance of proteolysis as a housekeeping activity that removes outgoing factors from
7 nput differentiates proton signaling from pH housekeeping activity.
8 ductase (GR), thereby supporting fundamental housekeeping and antioxidant pathways.
9  100 000 person-years [95% CI 593-809]), and housekeeping and factory workers.
10              We compared the pulsing of five housekeeping and five developmentally induced genes by d
11               Macroautophagy serves cellular housekeeping and metabolic functions through delivery of
12 ts and thus plays critical roles in cellular housekeeping and nutrient recycling.
13  to increase exposure to PBDEs and that good housekeeping and personal hygiene practices may reduce e
14   These experiments yielded 37 peptides from housekeeping and structural proteins (i.e., GroEL, EF-TU
15 ear coregulation adapted to accommodate both housekeeping and tissue-dependent metabolic needs.
16 riches for context-specific transcripts over housekeeping and/or structural RNA, and it preserves the
17 ribed and silent genes, repetitive elements, housekeeping, and tissue-specific genes.
18 o generate catabolites that are required for housekeeping biosynthesis processes.
19 thway which plays a crucial role in cellular housekeeping by internalization, transport, sorting and
20 first time that AGGF1 activates autophagy, a housekeeping catabolic cellular process, in endothelial
21      This study shows that KatG is the major housekeeping catalase of DC3000 and provides protection
22 ology categories were overrepresented, while housekeeping cellular functions were mainly transcriptio
23  genome and involved in regulation of either housekeeping/cellular maintenance genes or liver-specifi
24  in contrast to those metabolites exhibiting housekeeping characteristics?
25  indicates that such recruitment of cellular housekeeping components is a common feature used to inte
26 lular localization relative to the ancestral housekeeping desaturase may have allowed proto-SAD5's re
27 ansport, and mutations in the ubiquitous and housekeeping dynamin 2 (DNM2) have been associated with
28  endosomal membranes, thereby regulating the housekeeping endocytic transport in eukaryotes.
29                  Their turnover requires the housekeeping endonuclease RNase E and is activated by th
30 that interact with different core promoters: housekeeping enhancers (hkCP) and developmental enhancer
31              Deletion of the gene coding the housekeeping enzyme sortase A led to the release of NudP
32          In Salmonella enterica, CobA is the housekeeping enzyme that is required for de novo AdoCbl
33 ndings suggest that rather than serving as a housekeeping enzyme, MS has a broad and dynamic role in
34 hosphatase 1 (dCTPase) is a nucleotide pool "housekeeping" enzyme responsible for the catabolism of c
35  Although traditionally considered metabolic housekeeping enzymes because of their ability to detoxif
36       Aminoacyl-tRNA synthetases (aaRSs) are housekeeping enzymes essential for protein synthesis.
37 ption that they are largely constitutive and housekeeping enzymes.
38                          MTH1 is one of the "housekeeping" enzymes that are responsible for hydrolyzi
39           While the essential SecA1 handles "housekeeping" export, the nonessential SecA2 exports a s
40 binding protein profilin is believed to be a housekeeping factor that maintains a general pool of una
41 allows for a reversible sigma-switching from housekeeping factors to alternate sigma-factors when the
42    6S RNAs function through interaction with housekeeping forms of RNA polymerase holoenzyme (Esigma(
43 all RNA that binds within the active site of housekeeping forms of RNA polymerases (e.g. Esigma(70) i
44           BDE-153 was associated with higher housekeeping frequency (35.9%[0.4, 83.9%]) and BDE-209 w
45   In conclusion, seafood consumption, higher housekeeping frequency, and foam mattress were associate
46 curtains and carpets at home, mattress type, housekeeping frequency, and television use was also coll
47 r whether defects in this well characterized housekeeping function cause the specific degeneration of
48 sigma(70) These initial results pointed to a housekeeping function for this protein.
49 degradation of mitochondria, is an important housekeeping function in eukaryotic cells, and defects i
50  GTP dysregulation occurs, revealing a vital housekeeping function of (p)ppGpp; in fact, loss of (p)p
51 books depict metabolism as a well understood housekeeping function of cells.
52 fferocytosis is recognized as a constitutive housekeeping function of macrophages, these data indicat
53 vide evidence of another important metabolic housekeeping function of these glial cells.
54 hese results, we suggest that SOD1 carries a housekeeping function that maintains ROS levels below a
55                   VAPs have an intracellular housekeeping function, as well as an extracellular signa
56 tious disease, but also are involved in host housekeeping functions and can suppress allergic disease
57  during senescence: early down-regulation of housekeeping functions and metabolic processes followed
58                                Proteins with housekeeping functions and stable expression level such
59 netic states across cell types correspond to housekeeping functions and stimulus response, respective
60   We find that the coordinated regulation of housekeeping functions and tissue-specific gene expressi
61 t nonhost resistance mechanisms and pathogen housekeeping functions are conserved at deeper phylogene
62 ciples likely coordinate differentiation and housekeeping functions during progenitor cell differenti
63 genes but also the coordinated adaptation of housekeeping functions from a metabolically active, prol
64 that have been thought primarily to subserve housekeeping functions in cells-ribosomal RNAs, transfer
65                                          The housekeeping functions of autophagy in mediating the cle
66  but instead are often involved in essential housekeeping functions that are highly conserved across
67 veal that NF-Y regulates not only genes with housekeeping functions through cell type-invariant promo
68                         They are involved in housekeeping functions, metabolism (sugar, amino acids),
69 t protein homologues; instead, they affected housekeeping functions, such as signal recognition parti
70          We show that although FAS possesses housekeeping functions, under starvation conditions it i
71 al binding events are enriched at genes with housekeeping functions, while distal binding events inte
72  while also performing important homeostatic housekeeping functions.
73 fficient translation of genes with important housekeeping functions.
74 ates the translation of genes with important housekeeping functions.
75 s rendering them unable to perform important housekeeping functions.
76 t plants, features consistent with essential housekeeping functions.
77 r suited than stochastic switch behavior for housekeeping functions.
78 KAR2 under stress had no effect on its known housekeeping functions.
79 rmal tissues, which were highly enriched for housekeeping functions.
80 ble elements and structural genes for normal housekeeping functions.
81  have been shown to be enriched in essential housekeeping functions.
82 tified of which class A sortase is meant for housekeeping functions.
83 ed to nucleotide biosynthesis and a range of housekeeping functions.
84 g copies) and RNA transcripts from the GAPDH housekeeping gene (5.45 ng total mouse embryonic stem ce
85  there was no amplification of CRX; only the housekeeping gene (GAPDH) demonstrated amplification.
86 nching holes to deliver cholesterol-modified housekeeping gene (Gapdh) siRNA to the mouse ear skin.
87 Among children positive for the P falciparum housekeeping gene (PF08_0085; ubiquitin-conjugating enzy
88 tissue-specific transcriptional control of a housekeeping gene by a generic TF.
89 xpression domains in C(3), including typical housekeeping gene expression patterns in various tissues
90          We identified SNORD44 as a suitable housekeeping gene for qPCR analysis comparing normal and
91  which dominantly inherited mutations in the housekeeping gene GARS, which encodes glycyl-tRNA synthe
92              These results indicate that the housekeeping gene HPRT regulates purinergic signaling in
93 nant of Polycomb recruitment to the CGI of a housekeeping gene in somatic cells.
94                   The role of this metabolic housekeeping gene in tumorigenesis is still a matter of
95 , and CRISPR/cas) is its ability to cleave a housekeeping gene mRNA after being activated by a cancer
96  ii) tightly bind a structured fragment of a housekeeping gene mRNA, and iii) cleave it with efficien
97 or a gene therapy DNA machine that cleaves a housekeeping gene only in the presence of a cancer-causi
98             The 5,097 bp of the concatenated housekeeping gene sequence from the patient were 99.0% i
99 ed and identified to the species level using housekeeping gene sequencing.
100             We applied ScanDel to HPRT1, the housekeeping gene underlying Lesch-Nyhan syndrome, an X-
101  through retroposition of a highly conserved housekeeping gene, Caf40.
102 the core promoter -270GC-rich box of PIGM, a housekeeping gene, disrupts binding of the generic trans
103 -function mutations in the widely expressed, housekeeping gene, GARS The mechanisms underlying select
104 robust upregulation of this highly expressed housekeeping gene.
105 e compared to that of beta2 microglobulin, a housekeeping gene.
106 s suggest a surprising potential role for a 'housekeeping' gene in fine-tuning the development of an
107 y after photobleaching implied modulation of housekeeping-gene pulse strength occurs at the level of
108 agent was characterized by sequencing of six housekeeping genes (16S rRNA, ftsZ, gltA, groEL, ribC, a
109 free CpG island from the human HNRPA2B1-CBX3 housekeeping genes (A2UCOE) effectively prevents transge
110 ly 25% of expressed genes that are essential/housekeeping genes (e.g. RNA synthesis and splicing).
111                                              Housekeeping genes (HKG) are presumed to be constitutive
112 Diabrotica undecimpunctata howardi (Barber), housekeeping genes (HKG), beta-actin (Actin), beta-tubul
113                                              Housekeeping genes (HKGs) are essential for basic mainte
114                         Selection of optimal housekeeping genes (HKGs) as reference genes is critical
115 is dependent on normalization by appropriate housekeeping genes (HKGs).
116 as developed based on the sequences of eight housekeeping genes (ppa, pgm, gyrB, gmk, glyA, atpA, arc
117 ic proteins, but also repress a small set of housekeeping genes - such as those encoding lactate dehy
118 displays binary behavior, strongly expressed housekeeping genes altered the magnitude of their transc
119 erol (gpd1) caused a prolonged repression of housekeeping genes and a delay in gene activation at ind
120 those of four major gastric proteins and two housekeeping genes and comparable to the level of pepsin
121  an expanded eight gene version based on six housekeeping genes and two 'putative virulence' genes (e
122 , our analysis reveals that the locations of housekeeping genes are closely associated with cross-tis
123 ly bipartite organization in which conserved housekeeping genes are concentrated in syntenic gene-ric
124  We previously reported that specialized and housekeeping genes are differentially regulated via de n
125 ed during terminal erythroid maturation, but housekeeping genes are not preferentially lost.
126                                     By using housekeeping genes as a model, we demonstrated that XP-D
127 th been shown to be suitable alternatives to housekeeping genes as loading controls.
128 DR) approach, which employs stably expressed housekeeping genes as references to eliminate platform-s
129 s-related genes, and are reduced to encoding housekeeping genes as well as a protease subunit (clpP)-
130 ulation of a large number of genes including housekeeping genes as well as actively regulated genes.
131          When normalized with respect to the housekeeping genes B2M or GAPDH, mean tumor/normal ratio
132 spect to tissue weight or mRNA levels of the housekeeping genes B2M or GAPDH, were over-expressed in
133 parison to normalization with respect to the housekeeping genes B2M or GAPDH.
134 ve to either: tissue weight or levels of the housekeeping genes beta-2 microglobulin (B2M) and glycer
135 a set of randomly chosen genes, and a set of housekeeping genes broadly conserved in eukaryotes.
136                      As loss of neighbouring housekeeping genes can confer collateral lethality, we s
137 nes, and multilocus sequence typing of three housekeeping genes confirmed culture purity.
138 e groEL gene, and multilocus sequencing of 7 housekeeping genes confirmed the presence of a common st
139 IB dynamics that regulate specialized versus housekeeping genes during cardiac hypertrophy.
140  promoter regions of some of the most active housekeeping genes during interphase in human cells, but
141 rom positive controls, negative controls and housekeeping genes embedded in the nCounter system.
142    To search for the internal references, 10 housekeeping genes from a gut transcriptome of a wood-fe
143 ely removes highly expressed but nonspecific housekeeping genes from lens tissue expression profiles,
144 sponds to different functional classes, with housekeeping genes having few contacts, and dosage-sensi
145 such GAPs generated so far bear mutations in housekeeping genes important for parasite development in
146 interacts with transcriptional regulators at housekeeping genes in somatic cells is not well understo
147 or, to mechanistically dissect how essential housekeeping genes like TFR1 successfully balance the op
148 scription factors, effectors, and supportive housekeeping genes required for establishing and propaga
149     In this study, expression profiles of 16 housekeeping genes selected from C. maculata were cloned
150 ots typically involves normalization against housekeeping genes such as beta-actin.
151 rase III is highly conserved and transcribes housekeeping genes such as ribosomal 5S rRNA, tRNA and o
152 f bacterial communities by the sequencing of housekeeping genes such as that encoding the small subun
153 +)CD8(+) stage involved a global shutdown of housekeeping genes that is rare among cells of the immun
154  by a process that may be common among other housekeeping genes that reside in large regulatory domai
155 is brings about global repression and allows housekeeping genes to be expressed in all cells of the b
156 typing utilizing eight chromosomally located housekeeping genes to obtain information about species a
157   After in silico analysis, a final set of 7 housekeeping genes was selected (dnaA, metS, recA, tufA,
158 bolic functions, while mRNA levels for these housekeeping genes were low in cells at the bottom of th
159                                         Four housekeeping genes with allelic polymorphisms were ident
160 lity to find tissue- and cell line-optimised housekeeping genes without any prior bias, that again in
161 g improved reference genes over the cohort ('housekeeping genes') typically used for normalisation in
162 thermore, we present 692 uniformly expressed housekeeping genes, 43% of whose human orthologs are als
163 omains of early embryonic development genes, housekeeping genes, and constitutive regulatory elements
164 usually differ for gene density, GC content, housekeeping genes, and recombination frequency.
165 how that mOTUs, which are based on essential housekeeping genes, are demonstrably well-suited for qua
166 and IB), atpD (type II), and recA (type III) housekeeping genes, as well as a Fic family toxin gene (
167  11 H. ducreyi loci, including virulence and housekeeping genes, augmenting published data sets with
168  levels affect the polyadenylation levels of housekeeping genes, but not of p21 and c-fos genes, whic
169 leotide polymorphism (SNP) approach for nine housekeeping genes, characterizing penA alleles, and ant
170 al activation across cell lines, enriched in housekeeping genes, functionally related to fundamental
171 iption start site on many of the most active housekeeping genes, including genes encoding translation
172 o been shown to affect expression of E. coli housekeeping genes, including H-NS, a global regulator t
173 e to convergent losses of photosynthesis and housekeeping genes, making them excellent systems for st
174  II plays a role in incrementally increasing housekeeping genes, proportionate to the increase in hea
175 s, especially to conserved regions of common housekeeping genes, such as actin, alpha/beta-tubulin, a
176 biotic-producing functions and depleted from housekeeping genes, suggesting that they have a role in
177 MLST) scheme, comprised of seven single-copy housekeeping genes, to genetically characterize Trichomo
178 ched for the insulator binding protein CTCF, housekeeping genes, transfer RNAs and short interspersed
179 ion partners of functional fusions are often housekeeping genes, whereas the 3' fusion partners are e
180                                 In addition, housekeeping genes, which are routinely used as loading
181 d nucleotides that are often associated with housekeeping genes.
182 sistent with previous work employing nuclear housekeeping genes.
183 els of promoter SNP density are common among housekeeping genes.
184 ithout causing an outage of transcription of housekeeping genes.
185  contain both spliced and unspliced mRNAs of housekeeping genes.
186 affect expression or polymerase occupancy at housekeeping genes.
187 ng scheme (MLST) for P. acnes based on seven housekeeping genes.
188 lated species, including those encoding core housekeeping genes.
189 e only a small number of previously reported housekeeping genes.
190 nzymes needed in small amounts and even many housekeeping genes.
191 ription in many pathogens; they also control housekeeping genes.
192  is also common within constitutively active housekeeping genes.
193 genes, 43% of whose human orthologs are also housekeeping genes.
194             We found that the repression of "housekeeping" genes coincides with the transient activat
195 m mutations in a family of general "cellular housekeeping" genes is unknown.
196 ve chromatin and constitutively transcribed (housekeeping) genes.
197 ormalization across samples using reference (housekeeping) genes.
198 ys are spatially proximal to one another and housekeeping-genes tend to be proximal to several other
199 for at least one daily-living activity, with housekeeping, grocery shopping, and laundry being the ac
200 iscover lincRNAs expected to play a critical housekeeping (HK) role within the cell.
201                         We find that sets of housekeeping interactions provide a sensitive means of e
202 ichia coli, this process requires either the housekeeping Isc or the stress-induced Suf pathway.
203 ion observed in A. thaliana mainly producing housekeeping isoprenoid metabolites.
204 n remain problematic, due to the absence of "housekeeping" kinases and the obvious fallacy of the ass
205 ggravates the loss of RNA polymerase II from housekeeping loci, which apparently do not accumulate at
206                         We identify putative housekeeping, mammalian-specific, defense-related, and p
207 ydrogenase (GAPDH) is often used as a stable housekeeping marker for constant gene expression.
208 em, where it probably constitutes a baseline housekeeping mechanism and a first line of defence again
209 st chaperone gene expression is an essential housekeeping mechanism and provides a roadmap for defini
210 ted by TiO(2) nanoparticles and autophagy, a housekeeping mechanism that removes damaged cellular con
211 fatty acid-treated RAW264.7, respectively as housekeeping miRNAs.
212 nous ZnT8 from a basal level to 32.5% of the housekeeping Na(+)/K(+) ATPase on the cell surface, ther
213  in silico studies therefore reveal a set of housekeeping noncoding RNAs of interest both in terms of
214 tant over the two samples, which function as housekeeping normalization genes.
215 domain superfamily, CsrD, in addition to the housekeeping nucleases RNase E and PNPase.
216 llular constituents is critical for cellular housekeeping, nutrient recycling, and various aspects of
217 eep loss, suggesting that it may promote the housekeeping of heavily used and strong synapses in resp
218  of all specialized genes, while sparing the housekeeping ones, and, thus, attenuated pathological hy
219 Transcriptome analyses often have focused on housekeeping or tissue-specific genes or on gene coexpre
220 olism, demonstrating that a core gene in the housekeeping pathway of pterin biosynthesis has been coo
221 s mutated in IBMFS frequently participate in housekeeping pathways, which are important for cell grow
222 reated a mouse model that mimicked the human housekeeping pattern of fpgs gene expression.
223 ts, quantitates adduct levels relative to a "housekeeping peptide", and annotates modifications based
224  critical micellar concentration compared to housekeeping phospholipid analogs.
225 2alpha activity in the generation of a basal housekeeping PI3P pool and in the control of membrane re
226             Genome packaging is an essential housekeeping process in virtually all organisms for prop
227 ticipates in basic functional and structural housekeeping processes common to all cell types.
228  pivotal role in the mitophagy mitochondrial housekeeping program.
229  diverse developmental pathways and cellular housekeeping programs.
230 TFIIB is constitutively bound to all paused, housekeeping, promoters, whereas de novo recruitment of
231      We use this probe to measure kinase and housekeeping protein activities, separately or simultane
232 nly one protein per assay with an additional housekeeping protein for normalization.
233 stable isotope-labeled standard peptides (or housekeeping protein peptides), but quantitation using w
234 election on the transferrin receptor TfR1, a housekeeping protein required for iron uptake and the ce
235               Alternatively, it may act as a housekeeping protein that regulates the activity of endo
236 t cells requires its binding to an essential housekeeping protein, translation elongation factor Tu (
237               SMN1 encodes SMN, a ubiquitous housekeeping protein, which makes the primarily motor ne
238 encodes beta-actin, an abundant cytoskeletal housekeeping protein.
239 etases (aaRSs) have long been viewed as mere housekeeping proteins and have therefore often been over
240 s the major route of initiation of mRNAs for housekeeping proteins and thus, the bulk of protein synt
241 e trends were maintained for subsets of only housekeeping proteins and when moving from exomes of 1,0
242 factors, whereas the process likely involves housekeeping proteins as well.
243 at they have retained typical structural and housekeeping proteins found in nematocysts of jellyfish,
244                 Although peptides related to housekeeping proteins from nitrite-oxidizing microorgani
245 own that the expression level of such common housekeeping proteins is, in fact, dependent on various
246 athway involved in some cases recruitment of housekeeping proteins through gene duplication and their
247 ecursors for the synthesis of peptidoglycan, housekeeping proteins, and virulence factors in bacteria
248 he synthesis of the peptidoglycan cell wall, housekeeping proteins, and virulence factors of bacteria
249 ylation sites from 1,257 tissue-specific and housekeeping proteins.
250 mRNAs encoding ribosomal proteins and other 'housekeeping' proteins tending to have shorter tails.
251 atalytic mechanism distinct from that of the housekeeping PTAC.
252 dels successfully increased the inclusion of housekeeping reactions, which are often lost in models b
253 were categorized as constitutively expressed housekeeping, regulated homeostatic, or dynamic early st
254           RhoGDIalpha has been regarded as a housekeeping regulator essential to control homeostasis
255                        In this work, KsgA, a housekeeping ribosomal methyltransferase (rMtase) involv
256 d have come at some expense to the protein's housekeeping role in aminoacylation and editing.
257              We conclude that MT3 may play a housekeeping role in metal homeostasis, while MT4 may fu
258                               Aside from its housekeeping role in the assembly of snRNPs, additional
259  in Gram-negative bacteria has a more global housekeeping role, prompting our investigation to determ
260 eutically intractable owing to its essential housekeeping role.
261 ssemblies that have probably served cellular housekeeping roles for at least one billion years, ances
262 ass E sortase (SavSrtE) annotated to perform housekeeping roles in Streptomyces avermitilis Biochemic
263 maged DNA and also allow the study of normal housekeeping roles of PARP-1 with undamaged DNA.
264 t to be ubiquitously expressed and to serve 'housekeeping' roles in controlling protein homeostasis.
265 he crl gene has two overlapping promoters, a housekeeping, RpoD- (sigma(70)) dependent promoter, and
266                                          The housekeeping sarco(endo)plasmic reticulum Ca(2+) ATPase
267 ion in expression of stress-related, but not housekeeping, selenoproteins.
268 ma factor activity from competition with the housekeeping sigma factor for RNA polymerase and allows
269 nscription from the rrn promoter by both the housekeeping sigma factor holoenzyme (Esigma(70) ) and t
270  we analyzed the promoter specificity of the housekeeping sigma factor RpoD to promoters encoding pre
271  dependent upon a consensus sequence for the housekeeping sigma factor SigA and an A+T-rich upstream
272 ed by the RNA polymerase holoenzyme with the housekeeping sigma factor sigma(70).
273  sigma(G) but not promoters dependent on the housekeeping sigma factor sigma(A) .
274    Instead, MarA drives transcription by the housekeeping sigma(70) -associated RNAP.
275 gh rRNA transcription activities or when the housekeeping sigma(70) was sequestered, and was only sig
276 (Eco) 6S RNA interacts specifically with the housekeeping sigma(70)-holoenzyme (Esigma(70)) and plays
277 d can be suppressed by overexpression of the housekeeping sigma, SigA.
278 Mtb RbpA-SID in complex with domain 2 of the housekeeping sigma-factor, sigma(A).
279 erved region (NCR), which is present only in housekeeping sigma-factors.
280                                  Primary, or housekeeping, sigma factors are responsible for most of
281                          We discuss both the housekeeping sigmas, which govern transcription of the m
282                               The prototypic housekeeping sortase A (SaSrtA) from Staphylococcus aure
283                       Here, we show that the housekeeping sortase A (SrtA) enzyme promotes intestinal
284 be covalently linked to the cell wall by the housekeeping sortase A.
285 ve pili on the cell surface modulated by the housekeeping sortase are among the notable highlights.
286                    Genetic disruption of the housekeeping sortase in several Gram-positive pathogens
287 known adhesion-related proteins, such as the housekeeping sortase responsible for covalently linking
288  and that they govern the pilin-specific and housekeeping sortase specificity.
289 ral biofilms, that genetic disruption of its housekeeping sortase SrtA generates exceedingly long pil
290 xically, we discovered that depletion of the housekeeping sortase SrtA was lethal for Actinomyces ori
291 n CafA via modulation of pilus length by the housekeeping sortase SrtA.
292                             In addition, the housekeeping sortase, SrtA, was found to process EbpB an
293 enzymes - the pilus-specific sortase and the housekeeping sortase.
294 how coordination between differentiation and housekeeping states can be achieved by interconnected re
295 ched for specific transcription factors, non-housekeeping status, and genomic and 3D conformational p
296 UMOylations, and one (CrUBC3) is involved in housekeeping SUMOylations.
297 ences in stability between developmental and housekeeping transcripts, although strongly induced RNAs
298 t to no increase in H4K12 acetylation of the housekeeping tubA promoter.
299 iously for different groups of genes such as housekeeping versus regulated genes.
300 oter interactions differentially regulating "housekeeping" versus "developmental" genes.

 
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