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2 was 4.2 hours (interquartile range, 2.7-8.0 hr), divided into a median prehospital delay of 0.52 hou
3 to mesenchymal stem/stromal cell infusion (0 hr), 1 hour, 4 hours, 12 hours, 24 hours, and 72 hours a
11 in sera of individual PND 3 pups collected 1 hr postexposure utilizing ultra-high-pressure tandem mas
16 ctivity with recovery to near reference in 1 hr, followed by a slow activity decay to a stable, level
17 on-associated proteins in serum obtained: <1 hr (within 1-hour), 4-12 hr and 48-72 hr post injury.
20 ontractility of individual cells for up to 1 hr after seeding, while collective forces on longer time
22 ide (0.00012 +/- 0.00004 mumol N(2)O gDW(-1) hr(-1)) and carbon dioxide (3.556 +/- 0.471 mumol CO(2)
28 for covariates, women in the highest (>= ~11 hr/day) vs. the lowest (<= ~9 hr/day) quartile of sedent
29 timepoint images of embryos collected at 113 hr post-insemination, in embryo selection amongst 97 cli
31 the evening (LNd) group by approximately 12 hr; PDF alone delays the phase of the DN3 group by appro
33 mortality (area under the curve, 0.77 at 12 hr up to 0.93 at 5-10 d after cardiogenic shock onset).
34 ngth significantly predicted major delay (12 hr: odds ratio, 6.98; CI, 2.33-20.89; 8 hr: odds ratio,
35 igned to one of four groups (n = 6/group; 12 hr): 1) no spontaneous breathing activity and positive e
36 and 70 patients with circulatory shock (< 12 hr duration), defined as the need for vasopressors to ma
38 s of artificial kidney failure: early (<= 12 hr), intermediate (> 12-24 hr), and late (> 24 hr) in 35
41 stis sp. PCC 6803 metabolism that spans a 12-hr light/12-hr dark cycle by segmenting it into 12 Time
42 6803 metabolism that spans a 12-hr light/12-hr dark cycle by segmenting it into 12 Time Point Models
43 oxygenation (< 66 hr: odds ratio, 1; 66-128 hr: odds ratio, 0.281; 95% CI, 0.101-0.777; p = 0.014; 1
45 ian shift duration was 12 hours (range, 7-14 hr), and the median number of consecutive shifts allowed
47 exposure to a natural winter 9 hr 20 min:14 hr 40 min light-dark cycle as compared to the modern ele
48 e regional and age-specific prevalence of 14 hr-HPV genotypes as well as their prevalence in abnormal
49 er spending a weekend camping in a summer 14 hr 39 min:9 hr 21 min natural light-dark cycle compared
50 y shown that exposure to a natural summer 14 hr 40 min:9 hr 20 min light-dark cycle entrains the huma
58 isoniazid C(MAX) = 1,200 ng/ml, T(MAX) = 2.2 hr and T(1/2) = 4.7 hr), and two combination therapy pro
59 al activation (GFAP and CD68) and HMGB1 at 2 hr, 6 hr, 24 hr, 3 days, and 7 days postinjury, and seru
60 oading (n = 8, isotonic saline, 1 L/hr for 2 hr) or diuretic treatment (n = 8, furosemide, 40 mg ever
63 rgeted analysis of unfractionated lysates (2 hr) accurately reproduces the quantification of fraction
67 co) between burnt (432 +/- 83 mg CO(2) m(-2) hr(-1) ) and intact PSF (359 +/- 76 mg CO(2) m(-2) hr(-1
68 e-affected areas (7.8 +/- 2.2 mg CH(4) m(-2) hr(-1) ) compared to the intact PSF (4.0 +/- 2.0 mg CH(4
69 o the intact PSF (4.0 +/- 2.0 mg CH(4) m(-2) hr(-1) ) due to prolonged higher WT and more optimal met
70 ly higher CH(4) flux (0.88 +/- 0.03 mg m(-2) hr(-1) ) than spring thaw (0.48 +/- 0.04 mg m(-2) hr(-1)
73 s , 78.17 +/- 1.04%, 11.23 +/- 1.05 mg/cm(2)/hr, and 12.78 +/- 0.32%, respectively, while these value
75 by routine histology) in the OM, at 2 or 20 hr after termination of NA exposure, in humanized mice.
77 membrane oxygenation circuit at day 1 (10-23 hr), day 3, and day 7 of extracorporeal membrane oxygena
78 281; 95% CI, 0.101-0.777; p = 0.014; 128-232 hr: odds ratio, 0.474; 95% CI, 0.191-1.174; p = 0.107; a
79 4; 95% CI, 0.191-1.174; p = 0.107; and > 232 hr: odds ratio, 1.084; 95% CI, 0.429-2.737; p = 0.864; o
81 ure: early (<= 12 hr), intermediate (> 12-24 hr), and late (> 24 hr) in 35%, 31%, and 34% of circuits
84 by time to intubation (<= 8 hr: 38.2%; 8-24 hr: 31.6%; >= 24 hr: 38.1%; p = 0.7), and there was no a
88 rcadian clock that promotes approximately 24 hr rhythms in many behavioral and physiological processe
90 mulation produced lasting ( approximately 24 hr) enhancement of recollection precision, without effec
92 The mucosal transcriptional response at 24 hr revealed the involvement of activated T cells, which
96 that exhibited of 4,500- fold expression, 24 hr following exposure to the toxic compound 5-hydroxymet
97 /FIO2 (change in PaO2/FIO2 over the first 24 hr) were associated with mortality, whereas pressure var
102 Using a conventional dosing of 16 g/2 g/24 hr continuous infusion, obese patients were more likely
104 Carlo simulations showed that 12 g/1.5 g/24 hr was inadequate in both groups and 16 g/2 g/24 hr was
106 ), intermediate (> 12-24 hr), and late (> 24 hr) in 35%, 31%, and 34% of circuits, respectively.
108 ation (<= 8 hr: 38.2%; 8-24 hr: 31.6%; >= 24 hr: 38.1%; p = 0.7), and there was no association betwee
109 (GFAP and CD68) and HMGB1 at 2 hr, 6 hr, 24 hr, 3 days, and 7 days postinjury, and serum was collect
110 gly, RNA pol II-mediated RNA synthesis in 24 hr-treated cells was upregulated, indicating that, in co
113 ected for total body water and the sum of 24 hr urine plus total body water metabolites of PA, TYR, H
114 combination with colchicine treatment or 24 hr fasting, to assess NPY/Npy expression locally in the
115 Consumption of turkey during the past 24 hr was not associated with total arsenic or DMA during t
116 itatory synapses, whereas more prolonged (24 hr) firing depressed both AMPAR and NMDAR EPSCs and elim
117 ON or OFF medication, with memory tested 24 hr later ON or OFF medication (4 conditions, within-subj
118 further experiments were run without the 24 hr delay, but they too failed to reproduce effects of do
121 s) or lower dose heparin (up to 12,000 U/24 hr aiming for activated partial thromboplastin time < 45
122 was tested in a semiarid shrubland using 24 hr campaigns using two treatments: trenched plots and pl
123 orphological changes in LX-2 cells within 24 hr post-infection with HCV, HIV or HCV/HIV in MLH co-cul
124 se bats will exchange fat reserves within 24 hr, meaning that they must survive on the food of the da
126 posure-response analysis suggested that a 24-hr post-dose concentration of KAF156 of 21.5 ng/mL (90%
127 ariate method is based on collection of a 24-hr time series of plasma melatonin, a suprachiasmatic nu
128 Drosophila brain confer an approximately 24-hr rhythm onto locomotor activity are unclear, but invol
130 m was to evaluate the association between 24-hr dietary recall of poultry consumption and arsenic exp
132 erized by recessive inheritance of a long 26 hr period phenotype, encodes an RNA-binding protein that
133 2 mRNA rhythms were delayed by 0.97 +/- 0.29 hr (p < 0.01), indicating that human molecular clocks ma
134 lucose rhythms were delayed by 5.69 +/- 1.29 hr (p < 0.001), and average glucose concentration decrea
135 erquartile range]) life at 12.9 hr [5.5-21.3 hr]) hours than access dysfunction-free circuits (18.8 h
138 ic profile, with an initial plasma peak at 3 hr, followed by a rapid decline to a sub-therapeutic con
139 eral anesthetic, isoflurane (ISO, 1.5% for 3 hr), at three early postnatal ages (P3, P5 and P7).
147 nts' circadian rhythms were measured in a 37-hr constant routine that removes sleep and environmental
149 an mechanical ventilation time (25.2 vs 19.4 hr; p < 0.01), cardiac surgical ICU readmissions (5.3% v
150 nged emergency department to ICU time (> 2.4 hr) is associated with increased hospital mortality afte
153 ycan biosynthesis metabolites decreased at 4 hr by doripenem alone, reflecting its mechanism of actio
155 teoglycan components of PNNs were enhanced 4 hr after fear conditioning but were no longer different
161 to ectopic Erk signaling, except from 1 to 4 hr post-fertilization, when perturbing the spatial exten
162 f promoter-anchored chromatin loops within 4 hr after inducing differentiation of 3T3-L1 preadipocyte
166 patients than healthy patients (4.90 vs 1.48 hr) and was correlated with encephalopathy severity by G
169 vity drops precipitously during the first 48 hr of differentiation, corresponding to a release of C/E
170 her the relationship between early (first 48 hr) net ultrafiltration and mortality is mediated by flu
172 2 patients (57%) awoke: late awakening (> 48 hr from sedation stop; median time to awakening 5 days [
174 ere, we show that resveratrol (10 microM, 48 hr) induces both a cell growth arrest and a metabolic re
177 tshawytscha), and find that in less than 48 hr, males can upregulate sperm velocity when faced with
178 The analysis, which was completed in 1.5 hr, included loading data, annotation, principal compone
179 cardiopulmonary bypass was 4.6 hours (2-16.5 hr) compared with 170.4 hours (70-1,008 hr) on extracorp
180 anagement was implemented faster (1.9 vs 3.5 hr from 911 call; p < 0.001) and more frequently in the
184 me on ventilator (difference of median, 98.5 hr; p = 0.003) and length of ICU stay (difference of med
185 e assembled a novel MRI dataset containing 5 hr of RSFC data, 6 hr of task fMRI, multiple structural
187 h different post-mortem time delays (up to 5 hr) to mimic the way the human brain tissue is usually p
189 s (breakfast, lunch, dinner) were given at 5-hr intervals, beginning either 0.5 (early) or 5.5 (late)
191 ys for 24-hour intervals (median time, 18.52 hr); 31 (26%) for 12-hour intervals (median, 10.58 hr);
193 1 (26%) for 12-hour intervals (median, 10.58 hr); 117 (47%) for 8-hour intervals (median, 9.60 hr); a
195 anges in inundation duration between 2 and 6 hr/day did not affect SOM decay, the treatment without i
197 MRI dataset containing 5 hr of RSFC data, 6 hr of task fMRI, multiple structural MRIs, and neuropsyc
198 se in circulating WBCs, augment the early (6 hr postcecal ligation and puncture) recruitment of infla
199 d hydrocortisone at a 50 mg IV bolus every 6 hr and fludrocortisone as a 50 mug tablet once daily).
201 icting severe oliguria (< 0.3 mL/kg/hr for 6 hr) occurring within the next 12 hours were tested in th
203 ivation (GFAP and CD68) and HMGB1 at 2 hr, 6 hr, 24 hr, 3 days, and 7 days postinjury, and serum was
204 117 (47%) for 8-hour intervals (median, 9.60 hr); and 113 (72%) for 6-hour intervals (median, 9.55 hr
205 f 0.52 hours (interquartile range, 0.40-0.66 hr) and a median emergency department delay of 3.6 hours
206 of extracorporeal membrane oxygenation (< 66 hr: odds ratio, 1; 66-128 hr: odds ratio, 0.281; 95% CI,
207 odds ratio, 1.29; 95% CI, 1.02-1.64 (2.4-3.7 hr) and odds ratio, 1.54; 95% CI, 1.11-2.14 (> 3.7 hr),
208 d odds ratio, 1.54; 95% CI, 1.11-2.14 (> 3.7 hr), both compared with the reference category (< 1.2 hr
209 ,200 ng/ml, T(MAX) = 2.2 hr and T(1/2) = 4.7 hr), and two combination therapy protocols including dru
210 predefined time points (3, 6, 12, 24, 48, 72 hr), animals (>/= 6 per group) underwent echocardiograph
212 e quantification of fractionated lysates (72 hr analysis) while obviating the need for peptide detect
214 ave setup for the first time a long-term (72 hr) respiratory distress syndrome model in spontaneously
215 50,000 simulated exomes and it required 1.75 hr for the analysis of a quantitative trait using severa
216 ane administration was 3.33 hours (2.33-5.75 hr), range 1-19 hours with a mean consumption of 7.89 mL
218 (12 hr: odds ratio, 6.98; CI, 2.33-20.89; 8 hr: odds ratio, 23.70; CI, 8.13-69.11; 6 hr: odds ratio,
219 y did not differ by time to intubation (<= 8 hr: 38.2%; 8-24 hr: 31.6%; >= 24 hr: 38.1%; p = 0.7), an
220 n duration of monitoring was 47 hours (15-88 hr), and median duration from cardiac arrest to inclusio
221 (median [interquartile range]) life at 12.9 hr [5.5-21.3 hr]) hours than access dysfunction-free cir
222 ighest (>= ~11 hr/day) vs. the lowest (<= ~9 hr/day) quartile of sedentary time had higher risk for C
223 exposure to a natural summer 14 hr 40 min:9 hr 20 min light-dark cycle entrains the human circadian
224 a weekend camping in a summer 14 hr 39 min:9 hr 21 min natural light-dark cycle compared to a typical
226 fter a week's exposure to a natural winter 9 hr 20 min:14 hr 40 min light-dark cycle as compared to t
227 ained and applied on a large dataset (28,939 hr of data) using a stratified 20-fold cross-validation.
231 ventilation (weighted mean difference, -2.98 hr [95% CI, -5.08 to -0.89]; I = 34%; n = 334, five tria
232 perate at a sorting speed of up to 125 beads/hr (~3.5 times faster than a trained operator) providing
234 performed an associative memory task during hr-fMRI in which they encoded and later retrieved face-n
235 atients with OSA on placebo (AHI > 10 events/hr), AHI was lowered by 74% (62-88%) (P < 0.001) and all
237 sleep apnea (apnea-hypopnea index > 5 events/hr) were administered an antioxidant or placebo cocktail
238 , 8.1 +/- 2.2 years, AHI:11.1 +/- 5.9 events/hr), and 200 control subjects (84 male, 8.2 +/- 2.0 year
239 recessive ppd mutants on a spring-flowering hr mutant background show early, photoperiod-insensitive
242 = 0.015), time from admission to intubation (hr) (unit odds ratio, 1.01; 1.01-1.03; p = 0.017), and u
244 nds facilities, and an additional 116-186 kg hr(-1) formed from the photochemical oxidation of diesel
245 icate that AP infusion at the dose of 25U/kg/hr corrects serum and tissue AP deficiency and may preve
247 inimum urine output between 0.3 and 0.5mL/kg/hr), or 3) severe acute kidney injury (serum creatinine
248 , 0.15 mg/kg/hr (3.7 mg/kg/d) and 0.11 mg/kg/hr (2.8 mg/kg/d), increased by 36% and 58%, respectively
249 doses on the day of cannulation, 0.15 mg/kg/hr (3.7 mg/kg/d) and 0.11 mg/kg/hr (2.8 mg/kg/d), increa
250 g/kg/hr opioids (9.7 mg/kg/d) and 0.39 mg/kg/hr benzodiazepines (9.4 mg/kg/d) at decannulation, an in
251 ischarge, patients were receiving 0.40 mg/kg/hr opioids (9.7 mg/kg/d) and 0.39 mg/kg/hr benzodiazepin
252 d (propofol 2.6 +/- 1.2 vs 2.6 +/- 1.2 mg/kg/hr; p = 0.23 and remifentanil 1.27 +/- 0.17 vs 1.27 +/-
255 for predicting severe oliguria (< 0.3 mL/kg/hr for 6 hr) occurring within the next 12 hours were tes
256 ultrafiltration rate greater than 1.75 mL/kg/hr was associated with significantly greater mortality (
257 net ultrafiltration greater than 1.75 mL/kg/hr was independently associated with increased hospital
258 ne < 132 umol/L or urine output >= 0.5 mL/kg/hr), 2) mild-moderate acute kidney injury (serum creatin
262 h a net ultrafiltration less than 1.01 mL/kg/hr, a net ultrafiltration rate greater than 1.75 mL/kg/h
263 py clearance rates: 1) no clearance (0 mL/kg/hr, to measure adsorption), 2) low clearance (20 mL/kg/h
264 Reduction in morphine use of 0.25 mug/kg/hr (95% CI, -0.68 to 1.18 mug/kg/hr) was not statistical
269 units/kg/hr] vs 15.1 international units/kg/hr [10.7-18.3 international units/kg/hr] in the treatmen
270 se heparin dose (13.5 international units/kg/hr [9.6-17.9 international units/kg/hr] vs 15.1 internat
271 nits/kg/hr [10.7-18.3 international units/kg/hr] in the treatment and control group, respectively; p
272 units/kg/hr [9.6-17.9 international units/kg/hr] vs 15.1 international units/kg/hr [10.7-18.3 interna
273 weeks, at three levels of exposure (0.1 kGy/hr/wk [low], 1 kGy/hr/wk [medium] and 3 kGy/hr/wk [high]
276 r fluid loading (n = 8, isotonic saline, 1 L/hr for 2 hr) or diuretic treatment (n = 8, furosemide, 4
280 boli (adjusted risk ratio, 1.03/microembolus/hr; 95% CI, 1.01-1.05) and with persistently positive tr
281 at an infarct core growth rate (IGR) <4.1 ml/hr and initial infarct core volumes (ICV) <19.9 ml had a
284 efore angiotensin II initiation was 40 ng/mL/hr (normal, 0.6-3.0 ng/mL/hr) with resultant drop to 22
285 L/hr) with resultant drop to 22 and 12 ng/mL/hr at 2 and 6 hours after angiotensin II initiation, res
286 ation was 40 ng/mL/hr (normal, 0.6-3.0 ng/mL/hr) with resultant drop to 22 and 12 ng/mL/hr at 2 and 6
287 ed to infuse sustained low rates (0.15 mug / hr) of (R)-DOI.HCl to mice fed a high-fat "Western" diet
289 st NO(3) production was approximately 1 ppbv hr(-1), while NO(3) and N(2)O(5) were at or below 3 pptv
290 edian IP than qualified lr-MSM and qualified hr-MSM (2 [interquartile range {IQR}, 1-2] vs 3 [IQR, 2-
293 ied as low risk (lr) or medium-to-high risk (hr) based on self-reported sexual behavior and as qualif
294 utic vaccines have focused on two high-risk (hr) HPV genotypes, 16 and 18, and two viral targets, E6
296 rom December 1, 2016, to August 2, 2018, the hr-HPV prevalence among 60,135 women was 24.78%, the mos
299 h pentobarbital (Pento, 40 mg/kg body weight/hr) or propofol (Prop, 12 mg/kg body weight/hr), respect