ライフサイエンスコーパス: human adenovirus

1 EBER(I) (from Epstein-Barr) and VA(I) (from human adenovirus).

2 I) (from Epstein-Barr virus) and VA(I) (from human adenovirus).

3 DNA viruses mouse cytomegalovirus (MCMV) and human adenovirus.

4 y resembles hexon, the equivalent protein in human adenovirus.

5 these are limited by preexisting immunity to human adenoviruses.

6 s disease burden results from infection with human adenoviruses.

7 PCR using primers designed to amplify known human adenoviruses.

8 detection, identification, and serotyping of human adenoviruses.

9 understanding of pathoepidemiology among the human adenoviruses.

10 d-type and replication-incompetent bovine or human adenoviruses.

11 found to be similar in overall structure to human adenoviruses.

12 , PLDLS, conserved among the E1A proteins of human adenoviruses.

13 at may contribute to persistent infection by human adenoviruses.

14 gnaling, a function found to be conserved by human adenoviruses.

15 ent life cycles in these genetically distant human adenoviruses.

16 he latter activity of which was conserved by human adenoviruses.

17 disease (ARD) associated with subspecies B2 human adenovirus 11a (HAdV-11a) infection were detected

18 atory disease (ARD) among military recruits, human adenovirus 14 (HAdV-14) has historically been cons

19 and H10N8; variant influenza A H3N2 virus), human adenovirus-14, and Middle East respiratory syndrom

20 fluenza H3N2 variant virus in the USA, and a human adenovirus 14p1 also in the USA.

21 identical to that of the prototype strain of human adenovirus 16 [HAdV-16], Ch79) was isolated in Arg

22 ndicate that the E4ORF1 peptide derived from human adenovirus 36 (Ad36) interacts with cells from adi

23 Since the 1970s, replication-competent human adenoviruses 4 and 7 have been used as oral vaccin

24 nucleotide sequences with a high homology to human adenovirus 41 (HAdV-41) and simian adenovirus 1 (S

25 lification reaction of DNA from two viruses (Human adenovirus 41, Phi X 174) and the bacterium Entero

26 (+/-19)%, as model organism, as well as for human adenoviruses 42.4 (+/-3.4)% and murine noroviruses

27 s) by inoculation of a replication-defective human adenovirus 5 (Ad5) vector expressing IFNs can effe

28 -gamma) delivered by a replication-defective human adenovirus 5 (Ad5) vector protected swine when cha

29 Mutants of human adenovirus 5 (Ad5) with enhanced oncolytic activit

30 cells with a replication-competent strain of human adenovirus 5 (Ad5dl309) results in cytotoxicity.

31 derived from common human serotypes, such as human adenovirus 5 (AdHu5), is the high prevalence of vi

32 The cell-transforming activity of human adenovirus 5 (hAd5) E1A is mediated by the N-termi

33 ur unbiased proteomic analysis revealed that human adenovirus 5 (HAdv5) L-E1A was associated with man

34 endent neutralizing antibody in complex with human adenovirus 5 hexon and show how these properties i

35 The possibility that vaccination with a human adenovirus 5 vector increased mucosal T cell activ

36 bovine migrating DC to show that recombinant human adenovirus 5 vectors efficiently transduce afferen

37 2, herpes simplex virus 1, and nonenveloped human adenovirus 5.

38 ed five immunization strategies that include Human adenovirus-5 (AdHu5), Chimpanzee adenovirus-6 (AdC

39 The human adenovirus (Ad) early protein E4-ORF3 forms a uniq

40 Replication-defective human adenovirus (Ad) group C transducing vectors, most

41 Human adenovirus (Ad) is extensively used for a variety

42 The human adenovirus (Ad) serotype 5 has been tested in mala

43 respiratory illnesses associated with a rare human adenovirus (Ad) serotype, Ad14.

44 Human adenovirus (Ad) serotypes Ad3, Ad7, Ad11, and Ad14

45 s to the fiber gene that could differentiate human adenovirus (Ad) species A through F in a single am

46 g a variety of mammalian pathogens including human adenovirus (Ad), whose genomes encode a gene for m

47 Human adenoviruses (Ad) are double-stranded DNA (dsDNA)

48 chanisms that control cell-to-cell spread of human adenoviruses (Ad) are not well understood.

49 Early region 3 (E3) of group C human adenoviruses (Ad) encodes several inhibitors of tu

50 Human adenovirus (AdHu)-based candidate AIDS vaccine can

51 Species B human adenoviruses (Ads) are often associated with fatal

52 The E3 transcription unit of human adenoviruses (Ads) encodes immunomodulatory protei

53 Human adenoviruses (Ads) generally cause mild self-limit

54 The E3-19K protein from human adenoviruses (Ads) retains class I MHC molecules i

55 Human adenoviruses (Ads) typically cause mild illnesses

56 Mammalian cells infected with human adenoviruses (Ads) undergo an apoptotic response a

57 te a mechanism supporting the persistence of human adenovirus (AdV), a virus that can kill immunosupp

58 Human adenoviruses (AdV) have been implicated in a wide

59 nfection of non-enveloped viruses, including human adenoviruses (AdV), papillomaviruses (HPV), and po

60 apability of this approach to rapidly type a human adenovirus and several strains of human rhinovirus

61 iruses, we modeled the inactivation of three-human adenovirus and two bacteriophages-MS2 and phiX174-

62 ubiquitous source of polymorphic markers for human adenoviruses and demonstrates their use through an

63 ngue virus), DNA viruses (vaccinia virus and human adenovirus), and retroviruses (HIV).

64 on of herpes simplex virus 1 (HSV-1), HSV-2, human adenovirus, and human cytomegalovirus in cultured

65 as well the human polyomaviruses BK/JC/MCV, human adenoviruses, and human papillomaviruses.

66 rs are susceptible to infection with certain human adenoviruses, and the pathology accompanying these

67 Human adenoviruses are double-stranded DNA viruses respo

68 kly oncogenic, whereas most of the remaining human adenoviruses are nononcogenic.

69 Some human adenoviruses are tumorigenic in rodents.

70 We use human cells infected with human adenovirus as a complex and dynamic model to demon

71 Use of potently immunogenic human adenoviruses as vaccine vectors could overcome thi

72 munogenic, providing a viable alternative to human adenoviruses as vaccine vectors for human use.

73 transmembrane-containing proteins encoded by human adenoviruses, as a model system to survey the extr

74 cteriophage PRD1 and the double-stranded DNA human adenoviruses, as well as the viral proteins VP2-VP

75 G and IgM antibodies against influenza A and human adenoviruses based on the color and position of th

76 nt-like models that allow direct analysis of human adenovirus-based conditionally replicative adenovi

77 Adenovirus type 9 (Ad9) is distinct among human adenoviruses because it elicits solely mammary tum

78 Despite human adenoviruses being a common and, in some instances

79 that human defensin HD5 inactivates specific human adenoviruses by binding to capsid proteins and blo

80 ction limits of 1 x 10(3) virus particles of Human adenovirus C (HAdV), Human astrovirus (HAstV), and

81 Human adenovirus C (HAdV-C) species are a common cause o

82 HAdV-5 (Human adenovirus C) vectors are more immunogenic than ch

83 in encoded by the E3 transcription region of human adenoviruses called E3-13.7, which diverts recycli

84 Early region 3 genes of human adenoviruses contribute to the virus life cycle by

85 immunodeficient xenograft tumor models since human adenoviruses do not replicate effectively in murin

86 Human adenoviruses do not replicate in mice.

87 We have recently shown that E1A protein of human adenovirus downregulates epidermal growth factor r

88 n chimpanzee adenovirus vectors from species Human adenovirus E (ChAdOx1 and AdC68) in mice, though t

89 of Ad9 are closely related to those of other human adenovirus E1 regions.

90 The human adenovirus E1A 243 amino acid oncoprotein possesse

91 Human adenovirus E1A protein abrogated cotransactivation

92 Although it has been proposed that human adenovirus E1A recruits the Mediator complex to tr

93 for Sur2-E1A interaction, as is the case for human adenovirus E1A.

94 One important function of the human adenovirus E1B 55-kDa protein is induction of sele

95 The human adenovirus E3/19K protein is a type I transmembran

96 The human adenovirus E4 ORF 6 34 kDa oncoprotein (E4 34k), i

97 4 ORF1 and dUTPase proteins, we propose that human adenovirus E4 ORF1 genes have evolved from an ance

98 a genomic location analogous to that of the human adenovirus E4 ORF1s, was a genuine dUTPase enzyme.

99 Our findings indicate that most, if not all, human adenovirus E4-ORF1 proteins share a conserved mole

100 was carried out to investigate whether other human adenovirus E4-ORF1 proteins share this mechanism o

101 human T-cell leukemia virus type 1 Tax, and human adenovirus E4-ORF1, the functional consequences fo

102 l peptides equivalent to a region within the human adenovirus early region 1A protein that confers, i

103 Most human adenoviruses encode two virus-associated (VA) RNAs

104 Studies have revealed that human adenovirus-encoded E1A protein promotes cell proli

105 The E4-ORF1 gene of human adenoviruses encodes a 14-kDa protein that promote

106 Although species C human adenoviruses establish persistent infections, the

107 Human adenovirus expresses several early proteins that c

108 A549 (an epithelial-like cell line) using a human adenovirus expressing a beta-galactosidase reporte

109 udy was to alter the broad native tropism of human adenovirus for virus targeting to c-erbB2-positive

110 in MCF10A cells infected with each wild-type human adenovirus from subgroups A to D.

111 new type but also represented a new species (human adenovirus G).

112 Subgroup A and B human adenoviruses generally induce sarcomas in both mal

113 Attachment of human adenovirus (HAd) to the host cell is a critical st

114 Outbreaks of human adenovirus (HAdV) acute respiratory illness (ARI)

115 ctively to screen for the likely presence of human adenovirus (HAdV) and norovirus (NoV).

116 Several serotypes of human adenovirus (HAdV) cause acute respiratory disease

117 The genome of human adenovirus (HAdV) D30 was sequenced in depth.

118 timicrobial peptides capable of neutralizing human adenovirus (HAdV) in vitro by binding capsid prote

119 Human adenovirus (HAdV) infection mimics Kawasaki diseas

120 Severe human adenovirus (HAdV) infections are an increasing thr

121 An effective therapy for human adenovirus (HAdV) infections in immunocompromised

122 storically intriguing and predicted emergent human adenovirus (HAdV) pathogen, which caused pneumonia

123 was to characterize the etiological role of human adenovirus (HAdV) serotypes in pediatric gastroent

124 Human adenovirus (HAdV) types are associated with distin

125 overage, all 13 viral proteins present in an human adenovirus (HAdV) vector.

126 abs from 10 of 14 patients were positive for human adenovirus (HAdV) while swabs from 2 of 14 patient

127 however, an appropriate viral surrogate for human adenovirus (HAdV), a medium-sized virus with a dou

128 ange of waterborne viral pathogens including human adenovirus (HAdV), but the mechanisms by which fre

129 ay has improved sensitivity for detection of human adenovirus (HAdV), compared to an earlier version

130 vity of NVC-422 against several serotypes of human adenovirus (HAdV), coxsackievirus A24, enterovirus

131 For viruses that lack envelopes, such as human adenovirus (HAdV), other, less well defined, mecha

132 The search for human adenovirus (HAdV)-specific antiviral drugs for the

133 tion and deposition (adsorption) behavior of human adenovirus (HAdV).

134 Human adenoviruses (HAdV) are ubiquitous within the huma

135 Recombination in human adenoviruses (HAdV) may confer virulence upon an o

136 It has long been established that group A human adenoviruses (HAdV-A12, -A18, and -A31) can cause

137 Both drugs reduced the yields of four human adenoviruses (HAdV-A31, -B35, and -C5 and a specie

138 Subspecies B1 human adenoviruses (HAdV-B1s) are important causative ag

139 permissive for the replication of species C human adenoviruses (HAdV-C).

140 Human adenoviruses (HAdVs) are being explored as vectors

141 Human adenoviruses (HAdVs) are highly contagious pathoge

142 Human adenoviruses (HAdVs) are highly contagious pathoge

143 Human adenoviruses (HAdVs) are ubiquitous double-strande

144 Novel human adenoviruses (HAdVs) arise from genome recombinati

145 Human adenoviruses (HAdVs) contain seven species (HAdV-A

146 The role of human adenoviruses (HAdVs) in chronic respiratory diseas

147 pha/beta1-mediated nuclear import.IMPORTANCE Human adenoviruses (HAdVs) represent a ubiquitous and cl

148 Human adenoviruses (HAdVs) shut down host cellular cap-d

149 As one of the first five human adenoviruses (HAdVs) to be sequenced, type 17 was

150 We have recently reported that a group of human adenoviruses (HAdVs) uses desmoglein 2 (DSG2) as a

151 The recent emergence of highly virulent human adenoviruses (HAdVs) with new tissue tropisms unde

152 in IX molecules is conserved among different human adenoviruses (HAdVs), but not in non-HAdVs.

153 myocarditis, and the species specificity of human adenoviruses has limited the development of animal

154 Human adenoviruses have many attractive features for gen

155 eak of pneumonia associated with an emerging human adenovirus (human adenovirus serotype 14 [HAdV-14]

156 In addition, the most commonly used human adenovirus, human adenovirus subgroup C serotype 5

157 n, the first demonstration of replication of human adenoviruses in New World monkeys.

158 t time, we report that E4-ORF1 proteins from human adenoviruses in subgroups A to D evolved a conserv

159 ly detect a wide range of known serotypes of human adenovirus, including all of subgroups A to C.

160 ithin rhesus macaques is complicated because human adenoviruses, including human adenovirus type 5 (H

161 The subgroup C human adenoviruses induce selective export of newly synt

162 Human adenovirus infection activates intracellular signa

163 C4 inhibits human adenovirus infection by directly inactivating the

164 imicrobial peptides are potent inhibitors of human adenovirus infection.

165 ted in fatal disseminated disease resembling human adenovirus infections in immunocompromised patient

166 volutionarily conserved target of E4-ORF3 in human adenovirus infections.

167 Human adenoviruses interfere with a number of cellular p

168 Recombinant human adenovirus is a useful gene delivery vector for cl

169 The E1A gene of species C human adenovirus is an intensely investigated model vira

170 tribute of the E4-ORF3 proteins of different human adenoviruses is the ability to disrupt PML nuclear

171 icator viruses, eight human enteric viruses [human adenoviruses, JC and BK polyomaviruses, Aichi viru

172 demonstrate that the 5' noncoding region of human adenovirus late mRNAs, known as the tripartite lea

173 g suggests that immune evasion strategies of human adenoviruses may be directed, in part, toward prot

174 Genes within the E3 transcription unit of human adenoviruses modulate host immune responses to inf

175 We used MAV-1 to establish a mouse model of human adenovirus myocarditis, providing the means to stu

176 ession.IMPORTANCE To successfully replicate, human adenovirus needs to carry out a rapid yet ordered

177 A human adenovirus, ONYX-015, which has a deletion in the

178 del reproduced in mice what is observed with human adenovirus oral vaccines, it also highlighted that

179 Mature human adenovirus particles contain four minor capsid pro

180 ron tomography reconstructions of individual human adenovirus particles.

181 While human adenoviruses primarily produce self-limited acute

182 The interaction of the human adenovirus proteinase (AVP) and AVP-DNA complexes

183 The interactions of the human adenovirus proteinase (AVP) with polymers with hig

184 The interaction of the human adenovirus proteinase (AVP) with various DNAs was

185 tein of bacteriophage PRD1 resembles that of human adenovirus raised the unexpected possibility that

186 We found that human adenovirus replicates well in Syrian hamster cell

187 immunocompetent model that is permissive to human adenovirus replication in tumors as well as normal

188 rous mouse tissues are poorly permissive for human adenovirus replication.

189 endent pathway through which the E1A gene of human adenovirus sensitizes mouse and human cells to apo

190 ssociated with an emerging human adenovirus (human adenovirus serotype 14 [HAdV-14]) occurred on a ru

191 (i) the discovery of a new mechanism used by human adenovirus serotype 3 to overcome innate antiviral

192 es that priming with a replication-defective human adenovirus serotype 35 (Ad35) vector encoding circ

193 Human adenovirus serotype 4 (HAdV-4) is a reemerging vir

194 The human adenovirus serotype 5 (Ad5) is used widely for app

195 ulated plasmid DNA and replication-defective human adenovirus serotype 5 (Ad5) vaccine vectors expres

196 Using a human adenovirus serotype 5 (Ad5) vector and genetically

197 o-associated virus serotype 6 (AAV-po6), and human adenovirus serotype 5 (Ad5) vector, in a short-ter

198 Here, we show that an adjuvanted human adenovirus serotype 5 (Ad5)-vectored vaccine (Ad5-

199 f the most frequently used vector prototype, human adenovirus serotype 5 (Ad5).

200 Using wild-type and protein VI-mutated human adenovirus serotype 5 (HAdV-C5), we show that caps

201 , we describe the development of recombinant human adenovirus serotype 5 and modified vaccinia virus

202 In contrast, the same Ag vectored by human adenovirus serotype 5 induced clonotypic expansion

203 e was used to boost Ab responses primed by a human adenovirus serotype 5 vaccine recombinant for the

204 This human adenovirus serotype 5-protein regimen also induced

205 neutralized from sera of mice immunized with human adenovirus serotypes 2, 4, 5, 7, and 12.

206 Vaccine strains of human adenovirus serotypes 4 and 7 (HAdV-4vac and HAdV-7

207 f E4-ORF1 proteins encoded by representative human adenovirus serotypes from subgroups A to D induce

208 y affected by preexisting immunity to common human adenovirus serotypes, such as 2, 4, 5, 7, and 12.

209 Binding occurs in multiple human adenovirus serotypes.

210 d that desmoglein 2 (DSG2) is a receptor for human adenovirus species B serotypes Ad3, Ad7, Ad11, and

211 E3 transcription unit for 38 viruses within human adenovirus species D (HAdV-D) revealed distinct an

212 As vaccines, vectors derived from human adenovirus species D serotypes 26 and 48 (HAdV-D26

213 Human adenovirus species D type 19 (HAdV-D19) has been a

214 The E4-ORF1 protein encoded by human adenovirus stimulates viral replication in human e

215 on, the most commonly used human adenovirus, human adenovirus subgroup C serotype 5 (HAd5), when syst

216 Humans are infected by common serotypes of human adenovirus such as AdHu5 early in life and a signi

217 and destroyed in cells infected by species C human adenoviruses, such as type 5.

218 (simian adenoviruses) rather than with other human adenoviruses, suggesting a recent origin of HAdV-4

219 MPORTANCE Early region 3 proteins encoded by human adenoviruses that attenuate immune-mediated pathol

220 w adenovirus was so divergent from the known human adenoviruses that it was not only a new type but a

221 In the case of human adenovirus, this proteolytic cleavage is mediated

222 However, the inability of human adenoviruses to replicate efficiently in laborator

223 Human adenovirus type 12 (Ad12) E1A protein (E1A-12) is

224 viruses (CVB) cause human myocarditis, while human adenovirus type 2 (Ad2) is implicated as an agent

225 The human adenovirus type 2 E2 early (E2E) transcriptional c

226 The circulation of human adenovirus type 21 (HAdV21) in the United States h

227 Human adenovirus type 26 (HAdV26), which belongs to the

228 Human adenovirus type 36 (Ad-36) increases adiposity but

229 Experimental infection of rats with human adenovirus type 36 (Ad-36) promotes adipogenesis a

230 tes cellular glucose and lipid metabolism by human adenovirus type 36.

231 Human adenovirus type 37 (HAdV-37) is a major etiologic

232 tored ZIKV vaccine using a low-seroprevalent human Adenovirus type 4 (Ad4-prM-E) and compared it to a

233 The human adenovirus type 5 (Ad5) E1B 55-kDa protein is requ

234 The human adenovirus type 5 (Ad5) E1B 55-kDa protein modulat

235 Human adenovirus type 5 (Ad5) encoding rat insulin promo

236 possibility of cross-species replication of human adenovirus type 5 (Ad5) in canine cells.

237 opy, we have determined the structure of the human adenovirus type 5 (Ad5) to 3.6-A resolution and ha

238 le using a recombinant replication-defective human adenovirus type 5 (Ad5) vector, Ad5-boIFN-lambda3,

239 -molecular-weight (100K) assembly protein of human adenovirus type 5 (Ad5-100K) was previously define

240 structed a humanized monoclonal IgG1 against human adenovirus type 5 (AdV5) and a panel of Fc-enginee

241 ve virus purification material selective for human adenovirus type 5 (AdV5) offered highly purified v

242 Decoration of human adenovirus type 5 (hAd5) with folate, a known canc

243 icated because human adenoviruses, including human adenovirus type 5 (HAdV-5), are not endogenous to

244 ry of the pro-apoptotic gene PUMA to FLS via human adenovirus type 5 (HAdV5) vectors has been tested

245 ansforming human embryonic kidney cells with human adenovirus type 5 (HAV5) early region 1 (E1) seque

246 city of vaccines encoded by live recombinant human adenovirus type 5 (rAdHu5).

247 ctron counting, we improved the structure of human adenovirus type 5 and confirmed our previous model

248 cted by an E1B 55-kDa protein-null mutant of human adenovirus type 5 carry a large number of posttran

249 Priming with replication-deficient human adenovirus type 5 constructs and boosting with ex

250 eered DNA plasmids and replication-deficient human adenovirus type 5 constructs encoding large sectio

251 ontrast, infection with influenza B virus or human adenovirus type 5 did not induce significant level

252 in to investigate the mechanism by which the human adenovirus type 5 E1B 55-kDa protein protects agai

253 We show that human adenovirus type 5 encodes three proteins, named RI

254 ture, and swine inoculated with 10(9) PFU of human adenovirus type 5 expressing porcine IFN-alpha (Ad

255 Here, we have examined the L4P of human adenovirus type 5 in detail and have defined its t

256 e observation that the early region (E1A) of human adenovirus type 5 is directly linked to and may in

257 ame binding site in hexon; and noninfectious human adenovirus type 5 particles assembled in the absen

258 B-55K protein plays an important role during human adenovirus type 5 productive infection.

259 tem fabricated to deliver a live recombinant human adenovirus type 5 vaccine vector (AdHu5) encoding

260 Human adenovirus type 5 vectors (rAd5) encoding ebolavir

261 nstructed recombinant, replication-defective human adenovirus type 5 vectors containing either porcin

262 The nine known promoters from human adenovirus type 5 were analyzed for inherent DNA s

263 evaluate its efficacy, an adenovirus vector (human adenovirus type 5) encoding a green fluorescent pr

264 VA (Modified Vaccinia virus Ankara) and Ad5 (human adenovirus type 5) vectors both expressing Ag85A i

265 viral protein expression and replication by human adenovirus type 5, and dysregulates cellular gluco

266 Working with human adenovirus type 5, we showed previously that two p

267 iently transcomplemented by the E1 region of human adenovirus type 5.

268 A respiratory outbreak associated with human adenovirus type 7 (HAdV-7) occurred among unvaccin

269 (epidemic period) 85% of typed isolates were human adenovirus type 8 (HAdV-D8), whereas only low leve

270 Major oncogenic determinants for human adenovirus type 9 (Ad9) and high-risk human papill

271 The major oncogenic determinants for human adenovirus type 9 (Ad9) and high-risk human papill

272 Human adenovirus type 9 (Ad9) elicits exclusively estrog

273 In contrast, subgroup D human adenovirus type 9 (Ad9) induces estrogen-dependent

274 Human adenovirus type 9 (Ad9) is unique among oncogenic

275 Among oncogenic adenoviruses, human adenovirus type 9 (Ad9) is unique in eliciting exc

276 ssential oncogenic determinant of subgroup D human adenovirus type 9 (Ad9), which uniquely elicits es

277 Human adenovirus type 9 exclusively elicits mammary tumo

278 ted that the E4-ORF1 protein from subgroup D human adenovirus type 9 upregulates and oncogenically ac

279 ediates oncogenic cellular transformation by human adenovirus type 9, augments viral protein expressi

280 , 50, and 50 genomic copies per reaction for human adenovirus type B3 (HAdV-B3), HAdV-E4, HAdV-B7, HA

281 ermined in triplicate assays by incubating 9 human adenovirus types (1, 2, 3, 4, 5, 7a, 8, 19, and 37

282 d on the newly refined crystal structures of human adenovirus types 2 (Ad2) and Ad5 hexon.

283 le recombinant integrin alphavbeta5 bound to human adenovirus types 2 and 12 (Ad2 and -12) has been d

284 Similar to Ad5, E1A12S from human adenovirus types 2, 3, 9 and 12 suppressed EGFR, w

285 Human adenoviruses typically cause mild infections in th

286 not TFIIIA-independent transcription of the human adenovirus VA RNA gene.

287 IFN-alpha/beta) with a replication-defective human adenovirus vector (adenovirus 5 [Ad5]) can sterile

288 vestigations of the efficiency and safety of human adenovirus vector (AdV)-mediated gene transfer in

289 es the fidelity of the DNA polymerase into a human adenovirus vector.

290 Here, we report the structure of the whole human adenovirus virion at 3.6 angstroms resolution by c

291 nant vesicular stomatitis viruses (VSVs) and human adenoviruses was also evaluated.

292 Ad-2, another human adenovirus, was used as a negative control.

293 Ad-2, a nonadipogenic human adenovirus, was used as a negative control.

294 nse and the E3 immunoregulatory genes of the human adenovirus were unknown until now.

295 replication of P1/HRV2 in mice, recombinant human adenoviruses were used to express bicistronic mRNA

296 nslation and poliovirus tropism, recombinant human adenoviruses were used to express bicistronic mRNA

297 to show that pVIn is associated with mature human adenovirus, where it binds at the base of peripent

298 d by the immunologic heterogeneity of the 51 human adenoviruses, which are grouped from A to F on the

299 ry using a replication-defective recombinant human adenovirus with an early large T-antigen, had a mu

300 length and is most similar to subgroup E of human adenovirus, with 90% identity in most adenovirus t