ライフサイエンスコーパス: humoral immune response

1 ted antibacterial effector functions and the humoral immune response.

2 ndent on neither cytotoxic T lymphocytes nor humoral immune response.

3 antibody production, signifying an increased humoral immune response.

4 virus spread, which is resistant to the host humoral immune response.

5 cell formation, directly linking EG with the humoral immune response.

6 d virus as the vaccine is complicated by the humoral immune response.

7 elucidate the effect of the adjuvant on the humoral immune response.

8 nstruct and help B cells launch an effective humoral immune response.

9 the two main players of the T cell-dependent humoral immune response.

10 lutinin is the major antigenic target of the humoral immune response.

11 Abs to remove the pathogen that induces the humoral immune response.

12 gical effects of omega-3-derived SPMs on the humoral immune response.

13 immunization induced a robust and long-lived humoral immune response.

14 rotection and forms an important part of the humoral immune response.

15 ost cells and are the primary targets of the humoral immune response.

16 e virus may subvert the early HIV-1-specific humoral immune response.

17 al and participates in the regulation of the humoral immune response.

18 gM is the first antibody produced during the humoral immune response.

19 urther elucidated the role of mPGES-1 in the humoral immune response.

20 ance mechanism to limit accessibility to the humoral immune response.

21 ffects on virus replication and the adaptive humoral immune response.

22 ies tropism and a primary target of the host humoral immune response.

23 n (F) glycoproteins, the main targets of the humoral immune response.

24 ctivation, and the other associated with the humoral immune response.

25 ny adjuvant, which resulted in a significant humoral immune response.

26 hether and to what extent 9cRA modulates the humoral immune response.

27 high efficacy and potency to help Env trimer humoral immune responses.

28 on lymphocyte activation limits cellular and humoral immune responses.

29 ial for induction of potent and long-lasting humoral immune responses.

30 ccines continue to fail to induce these rare humoral immune responses.

31 on safety, reactogenicity, and cellular and humoral immune responses.

32 ted roles of LCs in type 17, regulatory, and humoral immune responses.

33 an immune system to induce both cellular and humoral immune responses.

34 c portion of IgG and important regulators of humoral immune responses.

35 arding the optimal approach for induction of humoral immune responses.

36 ins, most of which constitute key targets of humoral immune responses.

37 complex interplay between mucosal and serum humoral immune responses.

38 c in eliciting glycan-dependent cellular and humoral immune responses.

39 nfection and induced both systemic and local humoral immune responses.

40 in induction of germinal center B cells and humoral immune responses.

41 Tfh cells, resulting in marked impairment of humoral immune responses.

42 and maintenance of germinal center (GC) and humoral immune responses.

43 primary and secondary adaptive cellular and humoral immune responses.

44 iggered cellular immunity and cross-reactive humoral immune responses.

45 ce and are transforming our understanding of humoral immune responses.

46 zation strategies induce strong cellular and humoral immune responses.

47 egimen for both vaccine-induced cellular and humoral immune responses.

48 cells has complementary functions to promote humoral immune responses.

49 nity, in addition to potent and high-avidity humoral immune responses.

50 ulting in severe graft fibrosis and aberrant humoral immune responses.

51 lls) provide critical help to B cells during humoral immune responses.

52 pendent primarily on generation of effective humoral immune responses.

53 l responses and the development of effective humoral immune responses.

54 er, hypoxia elicited changes in cellular and humoral immune responses.

55 ce as a potential strategy for strengthening humoral immune responses.

56 distinct complement of adaptive cellular and humoral immune responses.

57 tion, nutrient dynamics, gene expression, or humoral immune responses.

58 roteins, and initiation of wound healing and humoral immune responses.

59 B cells retain the ability to participate in humoral immune responses.

60 e primary objective of noninferiority of the humoral immune response 1 month post-dose 2 was consider

61 ation before patients have mounted their own humoral immune responses(2,3).

62 ersistent, broad, and effective cellular and humoral immune responses able to delay heterologous SIVs

63 The humoral immune response after acute infection with HIV-1

64 lerability profile and induced rapid, robust humoral immune responses after 1 intramuscular dose of v

65 ide high-resolution molecular information on humoral immune responses after HuNoV vaccination and dem

66 We investigated the role of CD47 in inducing humoral immune responses after intranasal infection with

67 To examine the humoral immune response against B. miyamotoi, we infecte

68 orally administered to mice and generated a humoral immune response against both peptide antigen, an

69 lenge depended largely on the quality of the humoral immune response against EBOV GP.Here we present

70 ly to enhance the breadth and potency of the humoral immune response against HCV.

71 d are capable of contributing to the ongoing humoral immune response against Plasmodium infection.

72 avirus infection, a serological study of the humoral immune response against the individual viral pro

73 TCD colonization is associated with a humoral immune response against toxins A and B, with evi

74 d play important roles in T cell-independent humoral immune responses against blood-borne pathogens.

75 Germinal center formation and humoral immune responses against C. rodentium were sever

76 o the coat protein or as adjuvant to enhance humoral immune responses against coadministered Ags or v

77 Humoral immune responses against donor antigens are impo

78 ts/cells that are responsible for sustaining humoral immune responses against HIV.

79 Although studies analyzing humoral immune responses against SARS-CoV-2 were availab

80 za vaccine (QIV) and tested the cellular and humoral immune responses against the four vaccine strain

81 Humoral immune responses, albeit absent in completely pr

82 EZH2 histone methyltransferase mediates the humoral immune response and drives lymphomagenesis throu

83 ew networks that have important functions as humoral immune response and organismal injury/abnormalit

84 neutralizes viral variants that escaped the humoral immune response and reinfected the liver graft o

85 a susceptible hamster model in terms of the humoral immune response and survival from leptospiral ch

86 ction of N-deglycosylated hemocyanins in the humoral immune response and their nonspecific antitumor

87 t assay to define the characteristics of the humoral immune response and to determine seroprevalence.

88 anscription factor T-bet are associated with humoral immune responses and autoimmunity.

89 losteric inhibition in preclinical models of humoral immune responses and B-cell lymphomas.

90 MN vaccine induced superior humoral immune responses and conferred protective immuni

91 summarize the role of human Tfh cells during humoral immune responses and discuss the contribution of

92 ved the gastrointestinal conditions, induced humoral immune responses and drived protection against p

93 ed novel knowledge about the role of TL1A in humoral immune responses and its mechanism of action in

94 alled IL-40, that plays an important role in humoral immune responses and may also play a role in B c

95 ength HA antigens at inducing cross-reactive humoral immune responses and that VSV-cHA vaccine-induce

96 , we tested the immunogenicity (cellular and humoral immune responses) and efficacy (AD-like patholog

97 into host cells and is a key target for the humoral immune response, and yet many structural details

98 on and efficacy of HIV-specific cellular and humoral immune responses, and the preclinical modeling o

99 The BuV-specific humoral immune responses appeared to be strong and long-

100 cal tolerance that control both cellular and humoral immune responses are desirable.

101 that the suppressive effects on Ag-specific humoral immune responses are entirely B cell intrinsic.

102 e variants was not due to suppression by the humoral immune response as virus neutralising antibodies

103 that can provide insight into the underlying humoral immune responses, as well as important lessons t

104 Furthermore, T2D mice had an impaired humoral immune response at day 14 with reduced total IgG

105 Humoral immune responses at mucosal surfaces have histor

106 Humoral immune responses attack different parasite stage

107 During the humoral immune response, B cells undergo a dramatic chan

108 oses immense immunological challenges to the humoral immune response because of its ability to shield

109 ymphocyte subsets representing stages of the humoral immune response before and after antigen exposur

110 induces persistent SIV-specific cellular and humoral immune responses both systemically and at the or

111 Mice immunized with LANACs mounted a strong humoral immune response but did not produce neutralizing

112 Both forms of iNKT-cell help induce primary humoral immune responses, but only noncognate iNKT-cell

113 helper (Tfh) cells play a prominent role in humoral immune responses, but the mechanisms of their ac

114 elp to support germinal center reactions and humoral immune responses by antigen-specific wild-type B

115 s play an essential role in antigen-specific humoral immune responses by differentially regulating B

116 cells are necessary to generate and maintain humoral immune responses by providing help to antigen-sp

117 However, CPS-specific adaptive humoral immune responses can only be achieved by the cov

118 ation regimens that elicit both cellular and humoral immune responses can prevent HIV infection in hu

119 prehensive approach to systematically survey humoral immune responses, capturing the array of functio

120 In addition to eliciting humoral immune responses, CD4(+) and CD8(+) T cells char

121 mulation showed more robust and long-lasting humoral immune response compared to a single bolus injec

122 burden, resistant mice exhibited an elevated humoral immune response compared with susceptible mice.

123 dose, inducing a significantly more durable humoral immune response compared with three doses of a l

124 trated a strong, efficient, and safe in vivo humoral immune response compared with traditional forms

125 these vaccination regimens and cellular and humoral immune responses compared between the RV144 seri

126 that can induce strong and broad T cell and humoral immune responses correlating with HIV-1 protecti

127 V-positive C cases did not elicit long-lived humoral immune responses, despite viremia levels of up t

128 humanized mice to support the study of human humoral immune responses, discussing the current and fut

129 B cells ensure humoral immune responses due to the production of Ag-spe

130 rane fusion and is the primary target of the humoral immune response during infection.

131 Dysregulation of cellular and humoral immune response elements, along with organ-defin

132 To understand the humoral immune response elicited upon natural infections

133 We compared the HIV-1-specific cellular and humoral immune responses elicited in rhesus macaques imm

134 Common VH gene usage indicates common humoral immune responses, even among unrelated patients.

135 mas arise in the germinal center (GC), where humoral immune responses evolve from potentially oncogen

136 insic manner to mount an effective long-term humoral immune response following immunization.

137 hemagglutinin (HA) is a major target of the humoral immune response following infection and/or seaso

138 ays, despite the development of an effective humoral immune response following symptomatic primary in

139 The significance of humoral immune response for allograft survival after liv

140 pointed to the potential for harnessing the humoral immune response for early cancer detection.

141 This study shows the evolution of the humoral immune response from IgM to IgG DSA posttranspla

142 Although the humoral immune response generates the primary correlate

143 Humoral immune responses have the potential to maintain

144 immunity, but whether and how mTOR modulates humoral immune responses have yet to be fully understood

145 virus on viral replication and the adaptive humoral immune response.IMPORTANCE Using computer algori

146 Here we examine the humoral immune response in a subset of human volunteers

147 ecent findings related to B cells and to the humoral immune response in cancer and their translationa

148 odified Ad vectors boosted the OprF-specific humoral immune response in contrast to immunization with

149 activity, and neutralization capacity of the humoral immune response in ebolavirus survivors.

150 d individuals is likely due to a more intact humoral immune response in ECs and/or distinct responses

151 al targets on CHIKV that elicit a protective humoral immune response in humans are poorly defined.

152 replication was a consistent feature of the humoral immune response in immunized mice.

153 it is glycosylated, does not induce a strong humoral immune response in mice, and does not activate A

154 d a strong capacity to induce a long-lasting humoral immune response in mice.

155 e the repertoire of antigens associated with humoral immune response in pancreatic ductal adenocarcin

156 We determined and compared the humoral immune response in patients with severe (hospita

157 in alteration is associated with a decreased humoral immune response in Rictor KO mice.

158 ted that PvCSP-VK210 was the major target of humoral immune response in studied population, presentin

159 ynthetic DNA adjuvant, eliciting an enhanced humoral immune response in vaccinated mice.

160 ospheres significantly enhanced both Th1 and humoral immune responses in a mouse model of genital gon

161 In this study, humoral immune responses in CHIKV-infected patients and

162 ied Env proteins elicited potent and durable humoral immune responses in colorectal mucosa in rhesus

163 used to analyze the established cellular and humoral immune responses in healthy adults and asthmatic

164 r findings provide a better understanding of humoral immune responses in human cancer and suggest tha

165 e evaluated the generation of virus-specific humoral immune responses in infant (n = 6) and adult (n

166 nnate immune responses and downregulation of humoral immune responses in lymphoid tissues were confir

167 Advax(CpG) induced the highest cellular and humoral immune responses in mice.

168 immune disease and PD, impaired cellular and humoral immune responses in PD, imaging evidence of infl

169 HIV may each enhance mucosal HIV-1-specific humoral immune responses in sexually exposed but HIV-1-u

170 Adaptive humoral immune responses in the airways are mediated by

171 nts in cervical lymph nodes (CLN) to driving humoral immune responses in the infected CNS is poorly d

172 The patterns of humoral immune responses in the natural host are therefo

173 The protective role of B cells and humoral immune responses in tuberculosis infection has b

174 of PNSN(OVA + CpG) to stimulate cellular and humoral immune responses in vivo was compared with other

175 enchymal stromal cells play a key role in TD humoral immune responses in vivo.

176 macaques with bivalent VLPs generated strong humoral immune responses, including high titers of bindi

177 ings that form a framework for examining the humoral immune response induced by systemic orthopoxviru

178 for protective immunity, namely, V2-specific humoral immune responses inversely correlating with HIV

179 Anti-Id antibody responses (humoral immune responses [IRs]) were measured before eac

180 rotein antigens are conjugated with DNA, the humoral immune response is blunted and acquires features

181 fect on the induction and progression of the humoral immune response is not fully understood.

182 re the functional defect of the cellular and humoral immune response is often not recognized until th

183 et the relationship between severity and the humoral immune response is poorly understood.

184 ses, but their control of TFH cell-dependent humoral immune responses is unknown.

185 We compared humoral immune response kinetics in a panel study of sub

186 arly stages of infection when a delayed host humoral immune response likely affects virus systemic di

187 but HIV-induced dysfunction in the anti-HCV humoral immune response may play a role.

188 se of the peripheral nervous system in which humoral immune responses mediate tissue damage, inductio

189 , we sought to determine whether and how the humoral immune response might vary among controllers.

190 on and the extensive and variable breadth of humoral immune response observed in the volunteers at ba

191 We therefore analyzed the humoral immune response of mice chronically treated with

192 The humoral immune response of transplant recipients to infl

193 r inhibitory activities against cellular and humoral immune responses of S. exigua.

194 The humoral immune response over time was measured by ELISA.

195 HIV employs multiple means to evade the humoral immune response, particularly the elicitation of

196 Humoral immune responses, particularly immunoglobulin A

197 The humoral immune response plays an important role in the c

198 vement, cell-cell signaling and interaction, humoral immune response, protein synthesis, cell death a

199 The humoral immune response provides specific, long-lived pr

200 tly augmented and prolonged the cellular and humoral immune responses provoked by H5N1 and 2009 H1N1

201 lopment of assays capable of detecting early humoral immune responses.Recent advances in understandin

202 mic repertoire of antigens associated with a humoral immune response reflecting disease pathogenesis

203 lls play roles in both normal and pathogenic humoral immune responses regardless of host age.

204 -viral vector boosts to enhance cellular and humoral immune responses remains poorly understood.

205 Th2 helper cells that mediate cell-based and humoral immune responses, respectively.

206 p24CE DNA vaccination induced humoral immune responses similar in magnitude to those i

207 ine produced a more robust cell-mediated and humoral immune response than the systemic replicon vacci

208 nd toward higher HIV-1-specific cellular and humoral immune responses than did ALVAC-C, indicating th

209 es more potent antigen-specific cellular and humoral immune responses than those elicited by traditio

210 ion leads to the development of adaptive and humoral immune responses that are among the largest for

211 the PC that could be an important target of humoral immune responses that are involved in protection

212 that a live-attenuated HSV-1 vaccine elicits humoral immune responses that are unparalleled by a glyc

213 onses induced by nasal allergen exposure and humoral immune responses that included IgE-dependent bas

214 This approach enables humoral immune responses that may be difficult to elicit

215 They orchestrate humoral immune responses that modulate activities of oth

216 ating strains but can also stimulate broader humoral immune responses that potentially attenuate infe

217 skin DCs is their promotion of TFH cells and humoral immune responses that potentially represent an e

218 e podocyte, and both induce IgG4-predominant humoral immune responses that produce circulating autoan

219 iated activation of MZ B is known to trigger humoral immune response, the signal cascade directing th

220 nt is focused on the principal target of the humoral immune response, the spike (S) glycoprotein, whi

221 on the principal target of the neutralizing humoral immune response, the spike (S) glycoprotein.

222 lls (B(mem)) are essential for the secondary humoral immune responses, the chemokine response pattern

223 re of infectious HIV-1 correlated with other humoral immune responses, the extent of variation betwee

224 een proposed to mediate viral evasion of the humoral immune response, though the mechanisms are poorl

225 racteristics of antibodies that underlie the humoral immune response to a given antigen.

226 Moreover, the humoral immune response to a second antigen is also hamp

227 sponse but that IL-33 was needed to induce a humoral immune response to a single inhalational challen

228 We investigated the humoral immune response to Abeta42 fibrils and produced

229 ve TcdB, very little is known about the host humoral immune response to C. difficile and TcdB during

230 of CHIKV E2/E1 is the primary target for the humoral immune response to CHIKV, and antibodies targeti

231 new avenues to a better understanding of the humoral immune response to CMV and development of more e

232 otype 2 strain (R36A)] markedly inhibits the humoral immune response to coimmunized heterologous prot

233 The humoral immune response to decellularized scaffolds has

234 differences in the associations between the humoral immune response to EBV and disease risk across c

235 on of transcripts expressed during the human humoral immune response to find 30% of the human genome

236 te of a virion modulates the efficacy of the humoral immune response to flavivirus infection.

237 that the kinetics and quality of the infant humoral immune response to HIV are highly comparable to

238 underlie the best available examples of the humoral immune response to HIV are providing important i

239 uppression and viral breakthrough impact the humoral immune response to HIV infection.

240 In 430 participants, humoral immune response to HZ/su was noninferior in HZ-P

241 S/CpG and BCG vaccine generated a comparable humoral immune response to ID injection.

242 known about the nature and durability of the humoral immune response to infection with severe acute r

243 understanding of how pregnancy modifies the humoral immune response to influenza vaccination will ai

244 Additionally, the humoral immune response to LPS is an important component

245 Molecular determinants of human humoral immune response to N9 neuraminidase (NA) protein

246 The primary humoral immune response to natural infection is neutrali

247 We also detected and quantitated the humoral immune response to NiV by virus-specific immunog

248 ing that immunodominance plays a role in the humoral immune response to NoV infections.

249 Our results indicate that the humoral immune response to SHIV infection develops with

250 ine response in terms of anti-glycoprotein E humoral immune response to the adjuvanted recombinant zo

251 ents receiving the active treatment showed a humoral immune response to the MAGE-A3 antigen, although

252 kers able to monitor or predict a protective humoral immune response to the vaccine.

253 r of viral entry and the principal target of humoral immune response to the virus.

254 pp Deltapla mutant-immunized mice elicited a humoral immune response to the WT bacterium, as well as

255 Our findings indicate that a humoral immune response to this protein is not associate

256 on are transforming our understanding of the humoral immune response to viral infection.

257 Clearance was proposed to be mediated by humoral immune responses to amyloid.

258 the specific suppression of cellular and/or humoral immune responses to an Ag by prior administratio

259 to mount cross-reactive and cross-protective humoral immune responses to antigens from the most preva

260 ficantly less likely to develop long-lasting humoral immune responses to DENV, as measured in healthy

261 ozoans, and fungi, their potential impact on humoral immune responses to extracellular bacteria are u

262 In this Review, we compare the adaptive humoral immune responses to human immunodeficiency virus

263 Pregnant women do not have impaired humoral immune responses to IIV and may have increased c

264 Most humoral immune responses to influenza virus target the h

265 Humoral immune responses to influenza virus vaccines in

266 tudinal characteristics of cell-mediated and humoral immune responses to NiV infection during the acu

267 We analyzed humoral immune responses to nonhuman leukocyte antigen (

268 ion is associated with decreased mucosal and humoral immune responses to OPV but not the prolonged vi

269 fh) cells are critical for the generation of humoral immune responses to pathogenic infections, provi

270 The contribution of humoral immune responses to spontaneous control of hepat

271 synthetic oligosaccharide epitopes revealed humoral immune responses to the PS-I related glycan epit

272 a; and evaluation of the anti-glycoprotein E humoral immune responses to the vaccine compared with pl

273 imeric V1V2 scaffold alters the hierarchy of humoral immune responses to V2 region epitopes, providin

274 emulsion (GLA-SE) augments both cellular and humoral immune responses to vaccine Ags.

275 Humoral immune responses to varicella vaccine are best a

276 ntal understanding of coordinated aspects of humoral immune responses, to more globally differentiate

277 ere, we show that TBL1XR1 mutations skew the humoral immune response toward generating abnormal immat

278 a model Ag, we investigated the evolution of humoral immune responses toward its immunodominant seque

279 We monitored the humoral immune response under natural pollen exposure to

280 post-RABV immunization.IMPORTANCE Extending humoral immune responses using adjuvants is an important

281 egion as being significantly associated with humoral immune response variations after rubella vaccina

282 -binding cytokine interleukin (IL)-21 drives humoral immune responses via STAT3-dependent induction o

283 26 potential convalescent plasma donors, the humoral immune response was evaluated using a severe acu

284 Concurrent induction of potent cellular and humoral immune responses was also achieved by combining

285 Cell-mediated and humoral immune responses were assessed at baseline and f

286 t clinical symptoms, although DTMUV-specific humoral immune responses were detected.

287 nd ability to induce skin abscesses and host humoral immune responses were significantly attenuated i

288 This is best exemplified during humoral immune response when an expanding B cell clone a

289 We investigated cellular and humoral immune responses when allogeneic hepatocytes are

290 s indicate an essential role for LSD1 in the humoral immune response, where it modulates enhancer fun

291 , respectively, and induced balanced Th1/Th2 humoral immune responses, whereas mice immunized with th

292 ll subsets beyond the T1 stage and disrupted humoral immune responses, which can be recovered by addi

293 r signal-regulated protein kinase to inhibit humoral immune responses, while stimulating cell 'spread

294 This led to a balanced Env-specific humoral immune response with a more inflammatory Fc glyc

295 co-loaded with F1-V and MPLA induced potent humoral immune responses with 11-, 23-, and 15-fold incr

296 Previous efforts focused on priming humoral immune responses with recombinant HCV envelope E

297 Most subunit vaccines primarily generate humoral immune responses, with a weaker than desired CD8

298 ck of MOZ affected the functional outcome of humoral immune responses, with an increase in secondary

299 ent gp120 elicited high levels of T cell and humoral immune responses, with the vector containing a d

300 Suppressing unwanted humoral immune responses without compromising the host's