ライフサイエンスコーパス: hyaluronic acid

1 vitro and in vivo, including JAK2/STAT3 and hyaluronic acid.

2 ses in the abundance of soluble collagen and hyaluronic acid.

3 ices versus the active controls treated with hyaluronic acid.

4 CD44, capable of blocking binding to native hyaluronic acid.

5 , including mTOR, osteoglycin and binding of hyaluronic acid.

6 18, high-sensitivity C-reactive protein, or hyaluronic acid.

7 44, a cell-surface glycoprotein receptor for hyaluronic acid.

8 growth factor, hepatocyte growth factor, and hyaluronic acid.

9 3 months, and 22 used cross-linked forms of hyaluronic acid.

10 ream of hyl are also essential for growth on hyaluronic acid.

11 rted by direct binding of IgM to heparin and hyaluronic acid.

12 ced a systemic marker of inflammation, serum hyaluronic acid.

13 wn Norway rats by subretinal injection of 1% hyaluronic acid.

14 size was 0.39 (95% CI 0.18, 0.59), favoring hyaluronic acid.

15 more effective for pain than intraarticular hyaluronic acid.

16 The mice also received intraperitoneal hyaluronic acid.

17 12 it was 0.35 (95% CI 0.03, 0.66) favoring hyaluronic acid.

18 wn Norway rats by subretinal injection of 1% hyaluronic acid.

19 hyaluronidase family of enzymes that degrade hyaluronic acid.

20 express HYAL1 hyaluronidase, which degrades hyaluronic acid.

21 15, IFN-alpha, hepatocyte growth factor, and hyaluronic acid.

22 ar matrix components, including collagen and hyaluronic acid.

23 cilitates pancreatic cancer cell adhesion to hyaluronic acid.

24 covalently crosslinked hydrogels formed from hyaluronic acid.

25 in (12 kDa), chondroitin sulfate B (41 kDa), hyaluronic acid (1.6 MDa), and dextran (6 kDa).

26 ic ethanol feeding with small-specific sized hyaluronic acid 35 (HA35) normalizes TLR4 signaling; how

27 The control group received intra-articular hyaluronic acid (60 mg, single dose).

28 nds include bacterial lipopolysaccharide and hyaluronic acid, a component of the extracellular matrix

29 In contrast, addition of hyaluronic acid, a nonsulfated glycosaminoglycan, had no

30 Equipped with an outer shell crosslinked by hyaluronic acid, a specific tumour-targeting ligand, the

31 Equipped with hyaluronic acid, a tumour-targeting ligand, this formula

32 and significant reduction in accumulation of hyaluronic acid-a high molecular extracellular matrix gl

33 ation/reorientation, accompanied by restored hyaluronic acid accumulation in the palatal mesenchyme.

34 fabricated from natural polymers (chitosan, hyaluronic acid, alginates, gelatin, heparin, chondroiti

35 ic polymers polyethylene glycol, dextran, or hyaluronic acid also reduces inactivation in all three.

36 se-2 by DC maturation allowed degradation of hyaluronic acid and abrogated LC-DC interactions.

37 IPF, soluble factors such as short-fragment hyaluronic acid and cells such as CD11b(+) macrophages c

38 h selectivity (>90-fold) toward heparin over hyaluronic acid and chondroitin sulfate.

39 ctive over other glycosaminoglycans, such as hyaluronic acid and chondroitin sulfate.

40 ingly, when embedded in a 3D ECM composed of hyaluronic acid and collagen, BTICs exhibited opposite d

41 l brain, CSPGs are thought to associate with hyaluronic acid and glycoproteins such as the tenascins

42 identify the polyanionic glycosaminoglycans hyaluronic acid and heparan sulfate as two key macromole

43 Detectable hyaluronic acid and higher d-dimer, interleukin 6, inter

44 d that the interaction between C. neoformans hyaluronic acid and human brain endothelial CD44 could b

45 Hyaluronic acid and HYAL1-type hyaluronidase show high a

46 flexible or rod-like biopolymers, including hyaluronic acid and mucins, in the glycocalyx strongly c

47 r seems to function as the main receptor for hyaluronic acid and osteopontin, serving as coreceptor f

48 of the Scissor system using the ECM element hyaluronic acid and test formulations of insulin and fou

49 wn-Norway rats by subretinal injection of 1% hyaluronic acid and the intraretinal levels of the autop

50 ible hydrogel, based on thiol-functionalized hyaluronic acid and thiol-functionalized gelatin, which

51 ying two different biopolymers (alginate and hyaluronic acid) and mouse bone marrow stromal cells.

52 n microscopy shows that polyethylene glycol, hyaluronic acid, and albumin do not adsorb to the surfac

53 size was 0.22 (95% CI -0.05, 0.49) favoring hyaluronic acid, and at week 12 it was 0.35 (95% CI 0.03

54 timal ratios were controllably conjugated to hyaluronic acid, and elicited significant tumor reductio

55 spatial and temporal changes in tenascin-C, hyaluronic acid, and fibronectin ECM distribution as ear

56 coccal pyrogenic exotoxin B (SpeB), capsular hyaluronic acid, and proteins that allow host plasmin as

57 uction, whereas pulling on syndecan-1, CD44, hyaluronic acid, and with control probes did not.

58 lycan (GAG), generated from the sulfation of hyaluronic acid, are anti-inflammatory but have difficul

59 t the hypothesis that S. pneumoniae utilizes hyaluronic acid as a carbon source during colonization.

60 lginate, but poly-beta-D-glucuronic acid and hyaluronic acid as well.

61 minotransferase [AST]/platelet ratio, FIB-4, hyaluronic acid, AST/alanine aminotransferase ratio, and

62 We adapted the biophysical properties of hyaluronic acid-based hydrogels to support the different

63 Alternatively, when DOX was encapsulated in hyaluronic acid-based nanoparticles (HAC/DOX) and intrav

64 Herein, we developed hyaluronic acid-based substrates capable of sequential p

65 Recent advances in designing hyaluronic acid-based, actively targeted, hyaluronidase-

66 aluronan (HA) localization with biotinylated hyaluronic acid binding protein (b-HABP), and analyses o

67 PEPGPH20 was validated through staining with hyaluronic acid binding protein.

68 The hyaluronic acid-binding peptide (HABP) PEP35 was assesse

69 n is a large chondroitin sulfate-containing, hyaluronic acid-binding proteoglycan present in the extr

70 enotype is due to abundant production of the hyaluronic acid capsular polysaccharide, a key virulence

71 on of virulence factors, one of which is the hyaluronic acid capsule (encoded by genes in the has ope

72 eins (sfbI and fbp54), streptolysin O (slo), hyaluronic acid capsule (hasA), streptokinase (ska), and

73 including those for strong repression of the hyaluronic acid capsule and cysteine protease production

74 egulates the abundance of mRNAs encoding the hyaluronic acid capsule biosynthesis proteins (hasABC; a

75 tation in the hasA gene resulting in loss of hyaluronic acid capsule biosynthesis.

76 ve antigen, as well as hasACB, providing for hyaluronic acid capsule formation, two traits that each

77 demonstrate that pneumococci can utilize the hyaluronic acid capsule of other bacterial species for g

78 ticular, the pattern of polymorphisms in the hyaluronic acid capsule synthesis operon was especially

79 s encoding a two-component regulator and the hyaluronic acid capsule virulence factor.

80 nding (GRAB) protein, and the antiphagocytic hyaluronic acid capsule.

81 ed lower levels of the anthrax toxins and no hyaluronic acid capsule.

82 Pretreatment of chondrocytes with hyaluronic acid caused a decrease of mitochondrial DNA d

83 adenoviral vector transgene expression in a hyaluronic acid-CD44 independent manner that is down-reg

84 stigated the constituent of the PC formed by hyaluronic acid-coated chitosan NPs (HA-CS NPs).

85 onsist of an extracellular matrix containing hyaluronic acid, collagen fibers, but few elastic fibers

86 tion from skin tissue is challenging, as the hyaluronic acid-collagen matrix is extremely difficult t

87 d was attenuated in growth on cellobiose and hyaluronic acid compared to the growth of wild-type D39.

88 pathology and increased levels of pulmonary hyaluronic acid, compared to mice infected with the wild

89 with indirect lung injury, while circulating hyaluronic acid concentrations were elevated (32-fold) i

90 G (heparan sulfate, chondroitin sulfate, and hyaluronic acid) concentrations as well as patterns of h

91 mized to receive the matrix therapy agent or hyaluronic acid-containing eyedrops, 0.1%, every other d

92 The expression of hyaluronic acid, COX-2, and macrophage inflammatory prot

93 The chemical synthesis of a hyaluronic acid decasaccharide using the preactivation-b

94 st be aware of the potential for dextranomer/hyaluronic acid (Deflux) implants to mimic distal ureter

95 ctivity is substrate-dependent, with optimal hyaluronic acid degradation at pH 5, poly-beta-D-glucuro

96 idative/nitrosative damage and prevention of hyaluronic acid degradation.

97 ral routes for degradation by hyaluronidases-hyaluronic-acid-degrading enzymes-and oxidative stresses

98 nel-dependent LTP is known to be impaired by hyaluronic acid digestion.

99 Endogenous hyaluronic acid expression is markedly increased in DSS-

100 n, and 47 of 53 (89%) provided training with hyaluronic acid fillers.

101 nanoparticles are composed of biodegradable hyaluronic acid, for tumor targeting and cellular delive

102 , an inflammatory stimulus, such as low m.w. hyaluronic acid from the extracellular matrix, must also

103 We use this model to study the binding of hyaluronic acid functionalized with host molecules to tu

104 Unlike the hyaluronic acid gel commonly used in ophthalmic surgery,

105 Neuromodulators and hyaluronic acid gel fillers have been shown to be well t

106 A 3D model was then established using a hyaluronic acid-gelatin hydrogel to culture a mixture of

107 s been described, with botulinum A toxin and hyaluronic acid; graded full-thickness blepharotomy rema

108 matrix therapy agent group compared with the hyaluronic acid group (4.4 vs 6.1 days; mean difference,

109 n the matrix therapy agent group than in the hyaluronic acid group as measured with OCT (12.4 vs 23.9

110 d how E-selectin-dependent rolling modulates hyaluronic acid (HA) adhesion as a function of fluid she

111 been limited to analgesics, glucocorticoids, hyaluronic acid (HA) and a small number of unproven alte

112 plasmids encoding anthrax toxins as well as hyaluronic acid (HA) and B. cereus exopolysaccharide (BP

113 Charge interaction between polyanionic hyaluronic acid (HA) and cationic AuNPs stabilized with

114 We investigated the contributions of hyaluronic acid (HA) and chondroitin sulfate (CS) to glo

115 atrix (ECM), which is relatively enriched in hyaluronic acid (HA) and flexible.

116 Major constituents of the VB are hyaluronic acid (HA) and glycosaminoglycans (GAGs), both

117 sociated with a time-dependent deposition of hyaluronic acid (HA) and increased expression of markers

118 class I hyaluronan synthases (HASs) elongate hyaluronic acid (HA) by addition to the reducing or the

119 whey formulated media for the production of hyaluronic acid (HA) by Streptococcus zooepidemicus.

120 maturation were those that produced abundant hyaluronic acid (HA) capsular polysaccharide and/or larg

121 The hyaluronic acid (HA) capsule of GAS is a major virulence

122 nes (group A Streptococcus [GAS]) produces a hyaluronic acid (HA) capsule that plays critical roles i

123 Group A streptococcus (GAS) depends on a hyaluronic acid (HA) capsule to evade phagocytosis and t

124 zed a redox-sensitive nano-micelle formed by hyaluronic acid (HA) conjugated with d-alpha-tocopherol

125 c membrane consists of high molecular weight hyaluronic acid (HA) covalently linked to the heavy chai

126 Biological functions of hyaluronic acid (HA) depend on its molecular size.

127 Hyaluronic acid (HA) drug conjugates with distinct linke

128 A single treatment of hyaluronic acid (HA) filler, 20 mg/mL, may provide an im

129 Hyaluronic acid (HA) forms dynamic cross-links with bran

130 f neutrophil-attracting factors and protects hyaluronic acid (HA) from damage.

131 f our study was to evaluate the effects of a hyaluronic acid (HA) gel at 45 days on the microbiome of

132 Recently, hyaluronic acid (HA) has been suggested as an additional

133 t the development of a new cationic liposome-hyaluronic acid (HA) hybrid nanoparticle (NP) system and

134 We investigated synthetic, tunable hyaluronic acid (HA) hydrogels and determined both the a

135 Methacrylated hyaluronic acid (HA) hydrogels provide a backbone polyme

136 We developed a class of hyaluronic acid (HA) hydrogels that form through noncova

137 Shear-thinning, injectable hyaluronic acid (HA) hydrogels were formed through supra

138 Hyaluronic acid (HA) hydrogels were selected because of

139 e demonstrate that in covalently crosslinked hyaluronic acid (HA) hydrogels, the differentiation of h

140 This article describes the use of hyaluronic acid (HA) in combination with Rho-kinase inhi

141 erived hyaluronidase (HAase) HYAL-1 degrades hyaluronic acid (HA) into proangiogenic fragments that s

142 Hyaluronic acid (HA) is a highly abundant component in t

143 Hyaluronic acid (HA) is a large glycosaminoglycan abunda

144 Hyaluronic acid (HA) is a major component of the glycoca

145 Hyaluronic acid (HA) is abundant in cartilage and synovi

146 Because hyaluronic acid (HA) is found in many surgical viscoelas

147 High molecular weight hyaluronic acid (HA) is used as a lubricant in OA therap

148 and interleukin 6 (IL-6) levels and pre-ART hyaluronic acid (HA) levels were associated with new AID

149 nylboronic acid (CPBA), folic acid (FA), and hyaluronic acid (HA) molecules, by screening the 4-ATP S

150 sembling process to prepare docetaxel-loaded hyaluronic acid (HA) nanocapsules by using a self-emulsi

151 allenge using cisplatin loaded CD44 targeted hyaluronic acid (HA) nanoparticle (NP) induced synergist

152 ironments containing pathological amounts of hyaluronic acid (HA) or chondroitin sulfate (CS) did not

153 Hyaluronic acid (HA) promotes tumor metastasis and is an

154 The hyaluronic acid (HA) receptor for endocytosis (HARE) is

155 The hyaluronic acid (HA) receptor for endocytosis (HARE; als

156 satile method to transiently overexpress the hyaluronic acid (HA) receptor, CD44, on MSC membranes, t

157 , which includes inflammation, adipogenesis, hyaluronic acid (HA) secretion, and fibrosis.

158 4-Methylumbelliferone (4-MU) is a hyaluronic acid (HA) synthesis inhibitor with anticancer

159 e the potential of different formulations of hyaluronic acid (HA) to improve new bone formation in cr

160 Hyaluronic acid (HA), a glycosaminoglycan located betwee

161 face coating platform to non-covalently bind hyaluronic acid (HA), a natural lubricant in the body.

162 Hyaluronic acid (HA), an immunoneutral polysaccharide th

163 atrix remodeling was defined by detection of hyaluronic acid (HA), an inhibitor of preOL maturation,

164 the presence or absence of unlabeled sCD44, hyaluronic acid (HA), and a selected 10-mer HA binding p

165 l components of cartilage: type II collagen, hyaluronic acid (HA), and glycosaminoglycans (GAGs).

166 ression and release of heparan sulfate (HS), hyaluronic acid (HA), and sialic acid on human trophobla

167 al peptide of type III procollagen (PIIINP), hyaluronic acid (HA), and YKL-40 levels were determined

168 We identify hyaluronan, or hyaluronic acid (HA), as the primary matrix determinant

169 DS), chondroitin sulfate (CS), heparin (HP), hyaluronic acid (HA), chitosan (CH)] and model protein l

170 ntrinsic micro-regional interactions between hyaluronic acid (HA), collagen and the spatial origins o

171 regulate the metabolism and the signaling of hyaluronic acid (HA), the major component of the extrace

172 lodextrin (HP-beta-CD) was added into sodium hyaluronic acid (HA), the needle material.

173 to ensure that the viscous properties of the hyaluronic acid (HA)-based hydrogel are close to the bio

174 Here, a hyaluronic acid (HA)-based hydrogel is engineered to pre

175 ry, a matrix metalloprotease (MMP)-sensitive hyaluronic acid (HA)-based hydrogel was used for BMP-2 d

176 We hypothesized that hyaluronic acid (HA)-based in-situ crosslinkable hydroge

177 further functionalized this Zn-DPA analog to hyaluronic acid (HA)-based self-assembled nanoparticles

178 Importantly, we also found that hyaluronic acid (HA)-decorated CP/Ad-SS-GD/RNP nanocompl

179 (Se)-directed crosslinked hydrogels based on hyaluronic acid (HA)-dopamine (HD), including indocyanin

180 e and efficient strategy for this delivering hyaluronic acid (HA)-modified RNase A (RNase A-HA) in na

181 Additionally, the application of a hyaluronic acid (HA)-poly-L-glutamate cross polymer (HA-

182 little is known about how cells navigate the hyaluronic acid (HA)-rich, nanoporous ECM of the brain,

183 PP) anions and were successively coated with hyaluronic acid (HA).

184 sPLA(2) activity as chemical conjugates with hyaluronic acid (HA).

185 lfate (KS), chondroitin sulfate A (CSA), and hyaluronic acid (HA).

186 , GA was injected into a solution of 1.5 MDa hyaluronic acid (HA).

187 enhance topical delivery of a macromolecule, hyaluronic acid (HA, MW: 200-325kDa).

188 ed by formulating with a tocopherol-modified hyaluronic acid (HA-Toco) as a polymeric nano-suspension

189 ispersed in aldehyde- and hydrazide-modified hyaluronic acids (HA), then combined via a double-barrel

190 Here monodisperse synthetic hyaluronan (or hyaluronic acid [HA]) complexes in the approximately 1-

191 cascade activation [D-dimer], and fibrosis (hyaluronic acid [HA]) were measured at baseline and thro

192 Hyaluronan (hyaluronic acid; HA) instillation to the bladder has bee

193 ches have equal efficacy, but beyond week 8, hyaluronic acid has greater efficacy.

194 RD was induced by transscleral injection of hyaluronic acid (Healon) or sterile balanced salt soluti

195 Moreover, CCl(4)-induced serum hyaluronic acid, hepatic tissue levels of alpha-SMA or a

196 ic sperm injection (ICSI) include binding to hyaluronic acid (herein termed hyaluronan).

197 same building blocks previously employed for hyaluronic acid hexasaccharide syntheses failed to yield

198 platelet count, albumin, bilirubin, INR, and hyaluronic acid; however, changes in these did not corre

199 Vs are self-assembled from hypoxia-sensitive hyaluronic acid (HS-HA) conjugated with 2-nitroimidazole

200 y was used to test human DBM formulated with hyaluronic acid (HY) and cancellous and cortical bone gr

201 we developed a series of heparin-containing hyaluronic acid (HyA)-based hydrogels with various degre

202 arbon nanotube (A-MWCNT) functionalized with hyaluronic acid (Hyalu) and this mixture was separately

203 s paper shows that the injection of a porous hyaluronic acid hydrogel into the stroke cavity signific

204 Here, we show that a hyaluronic acid hydrogel system enables, across a physio

205 We developed a hyaluronic acid hydrogel that uses a tandem crosslinking

206 ESA was encapsulated in hyaluronic acid hydrogels during gel formation, and then

207 throughput platform based on light-modulated hyaluronic acid hydrogels that enables imposition of mut

208 cells (MECs) were cultured on methacrylated hyaluronic acid hydrogels whose stiffness can be dynamic

209 nt therapeutic mechanisms for the actions of hyaluronic acid in osteoarthritis.

210 may mediate ETV1's significant expansion of hyaluronic acid in PDAC stroma.

211 DSS induced a marked increase in hyaluronic acid in the lamina propria of wild-type but n

212 Cre;Etv1(fl/fl)) reduced levels of SPARC and hyaluronic acid in the stroma.

213 vel function for pneumococcal degradation of hyaluronic acid in vivo and provide mechanistic details

214 higher amounts of HYAL1 (in tumor cells) and hyaluronic acid (in tumor-associated stroma) than HYAL1-

215 Exogenous hyaluronic acid induced the expression of tumor necrosis

216 press a hyaluronate lyase (Hyl) that cleaves hyaluronic acid into disaccharides, we hypothesized that

217 ated in Brown Norway rats by injection of 1% hyaluronic acid into the subretinal space.

218 Injection of dermal filler, cross-linked hyaluronic acid, into the skin of individuals over 70 ye

219 The glycosaminoglycan hyaluronic acid is present on the apical surface of airw

220 Hyaluronic acid is widely used in the treatment of osteo

221 D44, known primarily for its role in binding hyaluronic acid, is characteristically expressed on HSPC

222 ementation, the intra-articular injection of hyaluronic acid, is widely used for symptomatic knee ost

223 Herein, the basic properties of hyaluronic acid, its binding partners, and natural route

224 evident both noninvasively and by increased hyaluronic acid levels (P < 0.01) at week 3.

225 Hyaluronic acid levels were significantly higher in the

226 c sinusoidal endothelium and increased serum hyaluronic acid levels, along with superior transplanted

227 ts were examined by tissue morphology, serum hyaluronic acid levels, and liver tests (endothelial and

228 ng heparan sulfate, chondroitin sulfate, and hyaluronic acid) lining the vascular lumen.

229 In addition to hyaluronic acid, lipids are particularly relevant for lu

230 a core-membrane structured lipid-polycation-hyaluronic acid (LPH) nanoparticle for systemic gene del

231 ith monosulfated (4-sulfated) and unsulfated hyaluronic acid matrices in microfluidics-based choice a

232 performance of LSM was comparable to that of hyaluronic acid measurement but superior to the aspartat

233 Protein kinase Calpha and the receptor for hyaluronic acid-mediated motility (RHAMM) regulate divis

234 k focuses on the investigation of injectable hyaluronic acid (MeHA) hydrogels that have tunable mecha

235 The cancer trap is composed of hyaluronic acid microparticles that have good cell and t

236 f doxorubicin in small molecular form versus hyaluronic acid nanoparticle (NP) formulation in MCF-7 a

237 sulated microRNA-34a in our well-established Hyaluronic-Acid nanoparticles and delivered to cisplatin

238 Using a norbornene-modified hyaluronic acid (NorHA) macromer as a representative bio

239 stigated the impact of small, specific-sized hyaluronic acid of 35 kD (HA35) on ethanol-induced sensi

240 However, nanomaterials based on hyaluronic acid offer a compelling strategy for reducing

241 Langerin recognized hyaluronic acid on DCs and removal of these carbohydrate

242 esized that the chondroprotective effects of hyaluronic acid on oxidatively stressed chondrocytes are

243 Engagement of CD44 by its natural ligands, hyaluronic acid or chondroitin sulfate, protected CLL ce

244 n-invasive markers of liver fibrosis such as hyaluronic acid or procollagen-III-peptide.

245 red with mesenchymal stromal cells (MSCs) or hyaluronic acid or when they were stimulated via ligatio

246 of albumin (P = .051), and higher levels of hyaluronic acid (P < .001) with an area under the receiv

247 Because heavy chain-hyaluronic acid/pentraxin 3 (HC-HA/PTX3) purified from h

248 A using hyaluronic acid-poly(ethylene imine)/hyaluronic acid-poly(ethylene glycol) (HA-PEI/HA-PEG) se

249 b-2 (miR-125b2) expressing plasmid DNA using hyaluronic acid-poly(ethylene imine)/hyaluronic acid-pol

250 zyme hyaluronidase (HysA), which cleaves the hyaluronic acid polymer at the beta-1,4 glycosidic bond.

251 ations of nanoclay are applied to cross-link hyaluronic acid polymers derivatised with a pendant bisp

252 al approaches, we show that depletion of the hyaluronic acid precursor UDP-glucuronic acid is suffici

253 ections of agents such as corticosteroid and hyaluronic acid preparations has been assessed.

254 EMT-induced metabolic reprogramming affects hyaluronic acid production, as well as associated extrac

255 in Th differentiation, osteopontin, but not hyaluronic acid, promoted Th1/Th17 differentiation.

256 Lymphatic vessel endothelial hyaluronic acid receptor (LYVE-1) is a recently defined

257 essed F4/80 and lymphatic vessel endothelial hyaluronic acid receptor and produced VEGFC.

258 nvestigated the presence on LAM cells of the hyaluronic acid receptor CD44 and its splice variants as

259 were enriched for cells expressing the major hyaluronic acid receptor CD44.

260 The hyaluronic acid receptor for endocytosis (HARE; also des

261 We also found that a secondary hyaluronic acid receptor, RHAMM (receptor of hyaluronan-

262 Similarly, sulfated hyaluronic acid (sHA) has not been evaluated for biologi

263 of genes involving PKA, Wnt, Lhx1, FGF8, and hyaluronic acid signaling regulating the transition of n

264 ng cells (TIC) in both Boyden chamber and 3D hyaluronic acid spheroid invasion assays.

265 ranching and reduced extracellular matrix by hyaluronic acid staining, all of which are associated wi

266 mals uniformly displayed clear reductions in hyaluronic acid staining.

267 atively, through the formation of cable-like hyaluronic acid structures.

268 Hyaluronic acid supported significant pneumococcal growt

269 , we identified a posteriorly-enriched gene, Hyaluronic Acid Synthase 2 (Has2), which encodes a key e

270 Hyaluronic acid synthase 2 was highly expressed, whereas

271 with aging, whereas in dermal sheath cells, hyaluronic acid synthase 2, HAS2, and PDPN increased and

272 cid and UDP-N-Acetyl-Glucosamine, as well as hyaluronic acid synthase which forms the disaccharide ch

273 so induced the MyD88-dependent expression of hyaluronic acid synthases 2 and 3, enzymes involved in h

274 ctivates angiogenesis, triggers collagen and hyaluronic acid synthesis and the formation of the extra

275 acid synthases 2 and 3, enzymes involved in hyaluronic acid synthesis, in lamina propria macrophages

276 that key components of this dynamic matrix, hyaluronic acid, tenascin-C and fibronectin, differentia

277 expression of a transitional matrix rich in hyaluronic acid, tenascin-C, and fibronectin controls mu

278 from lipid rafts can directly interact with hyaluronic acid, the C. neoformans ligand.

279 on addition of micromolar concentrations of hyaluronic acid, the resulting fluid viscoelasticity can

280 When osteopontin and hyaluronic acid, the two major ligands of CD44, were tes

281 red by subsequent layers of polyarginine and hyaluronic acid, thereby creating multi-layered assembli

282 Furthermore, exogenous hyaluronic acid, through the activation of TLRs and the

283 Our hypothesis is that hyaluronic acid, through TLRs, plays a protective role i

284 Serum hyaluronic acid, tissue inhibitor of metalloproteinase 1

285 d commercial kits to analyze serum levels of hyaluronic acid, tissue inhibitor of metalloproteinases-

286 Binding of hyaluronic acid to CD44 activates cell signaling pathway

287 231 than MCF-7 potentially due to binding of hyaluronic acid to CD44 expressed by MDA-MB-231.

288 Addition of polymers like dextran or hyaluronic acid to surfactant fully reverses inhibition

289 to 0.88) for the most efficacious treatment (hyaluronic acid) to 0.18 (CrI, 0.04 to 0.33) for the lea

290 ials that reported effects of intraarticular hyaluronic acid versus corticosteroids on knee OA were s

291 Hyaluronic acid was chemically modified with hydroxyethy

292 not MyD88(-/-), TLR4(-/-), COX-2(-/-) mice, hyaluronic acid was protective against DSS-induced colit

293 In wild-type mice, hyaluronic acid was therapeutic in established DSS-induc

294 tin-18 fragments), and hepatic fibrogenesis (hyaluronic acid) were measured.

295 nd to laminin, fibronectin, vitronectin, and hyaluronic acid, which are extracellular matrix elements

296 m subjects with IPF, we found short-fragment hyaluronic acid, which induced migration and proliferati

297 of EMT significantly increases production of hyaluronic acid, which is enabled by the reprogramming o

298 Hyaluronidases degrade hyaluronic acid, which promotes metastasis.

299 endocytosis and anthrax toxin lethality, and hyaluronic acid--which interferes with CD44-mediated int

300 abricated with biocompatible and dissolvable hyaluronic acid with a deep cave formed in the basal por