ライフサイエンスコーパス: hydrolysable

1 The addition of a non-hydrolysable 2'-deoxycytosine-5'-[(alpha,beta)-methyleno

2 With the synthesis of a non-hydrolysable [2-(19) F, 2-(13) C]-adenosine-triphosphate

3 nolics, extractable (8855.50mg GAE/100g) and hydrolysable (7005.51mg GAE/100g), than the other variet

4 Using in vitro assays, ACh and non-hydrolysable ACh analogs repressed the expression of con

5 with the catalytic nucleophile to form a non-hydrolysable adduct analogous to the mechanistic covalen

6 ly added topo II in a manner that depends on hydrolysable adenosine triphosphate (ATP), whereas an in

7 The non-hydrolysable ADP analogue, ADPbetaS, acting at P2Y1 rece

8 We prepare a non-hydrolysable ADPr-Ub probe that we employ in a proteomic

9 This fossil retains total hydrolysable amino acids of a roughly similar compositio

10 ctivity was stimulated by ATP but not by non-hydrolysable AMPPNP.

11 ion to ATP, a diminished response to its non-hydrolysable analog alphabetaMeATP, and a reduced contra

12 ty does not occur in the presence of the non-hydrolysable analog ATP-gammaS.

13 nd to GTPBP1 and aa-tRNA with GTP or the non-hydrolysable analog GDPCP, we show that the distinct GTP

14 des, ADP, and adenylyl-imidodiphosphate (non-hydrolysable analog of ATP).

15 '-[(beta,gamma)-imido]triphosphate, a poorly hydrolysable analog of GTP.

16 AMP and hydrolysable analogs of cAMP inhibited TbTOR4 expression

17 by either adenosine (100 microM) or its non-hydrolysable analogue 2-chloroadenosine (CADO; 0.1-5.0 m

18 However, in the presence of ATP, or the non-hydrolysable analogue 5'-adenylyl beta,gamma-imidodiphos

19 as the effect of ATP was mimicked by the non-hydrolysable analogue 5'-adenylylimidodiphosphate (AMP-P

20 It was found that AMP, ADP and the non-hydrolysable analogue adenylyl imidodiphosphate (AMP-PNP

21 In the presence of non-hydrolysable analogue beta,gamma-imidoadenosine 5'-triph

22 s enhanced by the presence of CTP or the non-hydrolysable analogue CTPyS.

23 n with Rac bound to either GDP or the slowly hydrolysable analogue GMPPNP show that the switch region

24 to NaV1.9, is upregulated by GTP and its non-hydrolysable analogue GTP-gamma-S, but not by GDP.

25 Upon binding of ADPNP (non-hydrolysable analogue of ATP), by PcrA, a conformational

26 Intracellular dialysis with the non-hydrolysable analogue of ATP, 5'-adenylylimidodiphosphat

27 te both in the presence and absence of a non-hydrolysable analogue of ATP, ADPNP.

28 The non-hydrolysable analogue of ATP, AMP-PNP, did not substitut

29 vator, forskolin, and the cell-permeable non-hydrolysable analogue of cyclic adenosine monophosphate

30 lso form in the presence of ATPgammaS, a non-hydrolysable analogue of the ATP required for translocat

31 The presence of ATP or a non-hydrolysable analogue, ADPNP, during limited proteolysis

32 h adenylyl imidodiphosphate (AMP-PNP), a non-hydrolysable analogue.

33 cells internally perfused with cAMP and non-hydrolysable analogues of cAMP.

34 Introducing non-hydrolysable analogues of GTP into the cytosolic compart

35 in the presence or absence of ATP and of non-hydrolysable analogues.

36 A total of 120 compounds, including hydrolysable and condensed tannins, flavonoids and pheno

37 ut also opens new opportunities to stabilize hydrolysable and high-charge-density cations for multiva

38 A wide range of different hydrolysable and poorly hydrolysable nucleoside triphosp

39 tor latrunculin, even in the presence of non-hydrolysable ATP (AMP-PNP).

40 e annealing activity is inhibited by the non-hydrolysable ATP analog (adenosine 5'-O-(thiotriphosphat

41 ures of the complex in the presence of a non-hydrolysable ATP analog reveal how nucleotide binding pr

42 in the presence of both phosphate and a non-hydrolysable ATP analog.

43 becomes irreversible in the presence of non-hydrolysable ATP analogs, resulting in a strong hyperpol

44 d GQ unfolding by BLM in the presence of non-hydrolysable ATP analogs, which has implications for the

45 , but not in the presence of ADP, GDP or non-hydrolysable ATP analogs.

46 nduced by the combination of peptide and non-hydrolysable ATP analogs.

47 , a G-protein activator (GTPgammaS) or a non-hydrolysable ATP analogue (AMPPcP).

48 trated that, following dialysis with the non-hydrolysable ATP analogue 5'-adenylylimidodiphosphate (A

49 The inability of the non-hydrolysable ATP analogue 5'-adenylylimidodiphosphate (A

50 The non-hydrolysable ATP analogue adenylylimidodiphosphate (AMP(

51 amp in the closed conformation using the non-hydrolysable ATP analogue ADPNP (5'-adenylyl beta,gamma-

52 ome core particle in the presence of the non-hydrolysable ATP analogue AMP-PNP at an overall resoluti

53 of ATP, or in the presence of ADP or the non-hydrolysable ATP analogue AMP-PNP, the interaction with

54 B glutamate (i.e. E1371) or by using the non-hydrolysable ATP analogue AMP-PNP.

55 edly inhibited response to AMP-PNP, a poorly hydrolysable ATP analogue that can nearly lock open the

56 g can be achieved in the presence of the non-hydrolysable ATP analogue, 5'-adenylyl beta,gamma-imidod

57 opyrum pernix in complexes with ADP or a non-hydrolysable ATP analogue, ADPNP.

58 resent the structure of EHD2, bound to a non-hydrolysable ATP analogue, and provide evidence consiste

59 mediated dissociation was abrogated by a non-hydrolysable ATP analogue, indicating that chaperone act

60 y adenylyl imidodiphosphate (AMP-PNP), a non-hydrolysable ATP analogue, is markedly diminished in K46

61 DNA substrates either with or without a non-hydrolysable ATP analogue.

62 form tubulin rings in the presence of a non-hydrolysable ATP analogue.

63 which was increased by the presence of a non-hydrolysable ATP analogue.

64 atch pipette or when substituted for the non-hydrolysable ATP analogues 5'-adenylylimidodiphosphate,

65 Previous studies using non-hydrolysable ATP analogues and hydrolysis-deficient cyst

66 ic depletion of eATP or competition with non-hydrolysable ATP analogues induced pathogenesis-related

67 These movements are driven by binding of non-hydrolysable ATP analogues to a monomer of SecA in assoc

68 ame ring, formed with either ATP, ADP or non-hydrolysable ATP analogues, suggesting that the specific

69 of the Ku80 vWA domain, and we show that non-hydrolysable ATP promotes synapsis by stabilising the Ku

70 anion selectivity sequence, requirement for hydrolysable ATP) in Pgp-expressing cells were different

71 currents from inhibition needs intracellular hydrolysable ATP, presumably for PIP(2) resynthesis.

72 predominantly monomeric, AMP-PNP-DnaA (a non-hydrolysable ATP-analog bound-DnaA) was oligomeric, prim

73 One such factor has been identified as hydrolysable ATP-Mg although the mechanism for ATP funct

74 o bind RNA, and RNA binding was prevented by hydrolysable ATP.

75 ing, while formation of the DH also requires hydrolysable ATP.

76 re beta,gamma-complex in the presence of non-hydrolysable ATPgammaS, indicating that an intact RecA f

77 substrate, casein in the presence of slowly hydrolysable ATPgammaS, which reveal the translocation m

78 Xylanase hydrolysable AX are likely also released by microbiota's

79 tations, such as restricted enzyme access to hydrolysable bonds, prohibit more extensive deconstructi

80 phosphate (Ins 2,4,5-P3) is known to be less hydrolysable by the InsP3-5-phosphatase than is Ins 1,4,

81 The high soil acid-hydrolysable C to total organic C ratio at bamboo planta

82 amboo increased microbial C and N, soil acid-hydrolysable C, recalcitrant C, and soluble organic C of

83 of ICa to cAMP could be reversed by the non-hydrolysable cAMP analogue 8-Br-cAMP or the phosphodiest

84 tylmethylxanthine (IBMX; 10 microM), the non-hydrolysable cAMP analogue 8-bromo-cAMP (1 mM), or the a

85 Thus, carnosine, or non-hydrolysable carnosine analogs, may represent a new clas

86 light, or by dialysing the cells with a non-hydrolysable cGMP analogue.

87 focussed on the integration of more or less hydrolysable components to modulate degradation rates.

88 Hydrolysable ester conjugates of PEG(1)(0)(0)(0), PEG(2)

89 ctrum glucocorticoid, using a combination of hydrolysable ester linkers derived from succinic anhydri

90 In the absence of a hydrolysable form of ATP, the distance across the subuni

91 nosine, or intracellular infusion of the non-hydrolysable GTP analog 5'-guanylylimidodiphosphate (Gpp

92 A cold-stable tubulin polymer with the non-hydrolysable GTP analogue GMPCPP, containing semi-conser

93 e crystal structure of Cdc42Hs, with the non-hydrolysable GTP analogue GMPPNP, in complex with the GA

94 rhoGAP, in which Cdc42Hs is bound to the non-hydrolysable GTP analogue GMPPNP.

95 man gamma-tubulin bound to GTP-gammaS (a non-hydrolysable GTP analogue).

96 orm a continuous surface stabilized by a non-hydrolysable GTP analogue, and Sar1 has rearranged from

97 otriphosphate (GTPgammaS, 100 microM), a non-hydrolysable GTP analogue, mimicked the FMRFamide inhibi

98 2-Ran x GppNHp complex where GppNHp is a non-hydrolysable GTP analogue.

99 produced by intracellular dialysis with non-hydrolysable GTPgammaS.

100 Non-hydrolysable guanine nucleotide analogues (GDP-beta-S an

101 gs made with an electrode containing the non-hydrolysable guanosine triphosphate analogue, guanosine

102 antioxidant capacity of extractable (EP) and hydrolysable (HP) polyphenols in murta juice.

103 lly related analogues that are poorly or non-hydrolysable is sufficient to induce opening.

104 GMT was chemically modified with a hydrolysable linker, and subsequently incorporated into

105 d to a hyaluronic acid backbone using either hydrolysable linkers (hSAgAs) or stable click chemistry

106 s, alternative PP-InsP stereoisomers, or non-hydrolysable methylene bisphosphonate analogs ("PCP-InsP

107 e range of different hydrolysable and poorly hydrolysable nucleoside triphosphates were used to eluci

108 import could no longer be inhibited with non-hydrolysable nucleotide analogues, indicating that no Ra

109 loenzymes, but only when the activator and a hydrolysable nucleotide was added and the DNA was opened

110 Although non-hydrolysable nucleotides are sufficient for channel func

111 urve, different concentrations of the poorly hydrolysable nucleotides, ATPgammaS and ADPbetaS, could

112 with minimal effect upon the addition of non-hydrolysable nucleotides.

113 lyphenols and include tannins, classified as hydrolysable or condensed.

114 This study is the first to demonstrate hydrolysable PEG drug ester conjugates are a promising a

115 The prepared hydrolysable polyGMT NPs demonstrate ultra-long release

116 monstrate the ability to polymerize GMT in a hydrolysable polymer structure, and engineer NPs of this

117 Such controlled release hydrolysable polymers with very high drug loading and co

118 unfermented samples) were identified in the hydrolysable polyphenol fraction, demonstrating the cont

119 he importance of integrating extractable and hydrolysable polyphenol fractions to broaden the utiliza

120 3-O-glucoside), Cristalina and Seleccion of hydrolysable polyphenols (gallic acid 3-O-gallate, cinna

121 than 15% to total antioxidant activity, and hydrolysable polyphenols give a major contribution; carc

122 sixty-eight extractable polyphenols, fifteen hydrolysable polyphenols, forty-one betalains, sixteen c

123 Pre-extraction of enzymatically-hydrolysable starch and xylan reduced the release of fur

124 ncluding its thermal properties and built in hydrolysable structure, are thus conducive for use in th

125 e of the enzyme co-crystallised with the non-hydrolysable substrate analogue 2,6-diketo-nona-1,9-dioi

126 The positions of the inhibitor (the non-hydrolysable substrate analogue dUDP) and the metal ion

127 the C.jejuni dUTPase in complex with the non-hydrolysable substrate analogue dUpNHp allows us to defi

128 as been crystallized in complex with the non-hydrolysable substrate analogue S-(2-oxo)pentadecyl-CoA,

129 rmophilus elongation complex (EC) with a non-hydrolysable substrate analogue, adenosine-5'-[(alpha,be

130 wo parts, modified each with appropriate non-hydrolysable substrate analogues(13,14), assembled the t

131 For both high total phenolic, hydrolysable tannin and anthocyanins contents, as well a

132 ort that low dose of chebulagic acid (CA), a hydrolysable tannin found in myrobalan fruits can inhibi

133 Oenothein B, a dimeric hydrolysable tannin, dose-dependently induced a number o

134 the previously identified proanthocyanidin, hydrolysable tannin, flavonoid, and phenolic acid classe

135 enolic acids (13), monomeric flavonoids (8), hydrolysable tannins (12), proanthocyanidin (1) and anth

136 the contents of total phenolics (7.2-17.2%), hydrolysable tannins (16.7-59.5%) and anthocyanins (11.7

137 This study identified and quantified hydrolysable tannins (HTs) in Terminalia ferdinandiana E

138 thocyanins, 4 flavanols, 4 phenolic acids, 2 hydrolysable tannins and 31 flavonols in petal liqueurs.

139 identification of up to 39 chemicals, being hydrolysable tannins and anthocyanins the predominant st

140 Hydrolysable tannins and ellagic acid were identified as

141 entified were from the quercetin family, the hydrolysable tannins and fatty acids and their derivativ

142 noids, phenolic acids and related compounds, hydrolysable tannins and related compounds, and other ph

143 In conclusion, the use of hydrolysable tannins can represent a promising tool for

144 concentrations of riboflavin and methionine, hydrolysable tannins from various sources (nut galls, ch

145 te a sizeable fraction of phenolic acids and hydrolysable tannins in the whole fruit.

146 Hydrolysable tannins were prevalent, namely Sanguiin H-1

147 Hydrolysable tannins were the main phenolic compounds id

148 punicalagin and alpha-punicalagin (the major hydrolysable tannins) against clarification were similar

149 ized models were exposed to tannic acid (TA, hydrolysable tannins) and grape seed extract (GSE, conde

150 itosan and xanthan gum)] on total phenolics, hydrolysable tannins, anthocyanins and antioxidant activ

151 extracts from salad burnet were dominated by hydrolysable tannins, comprising mainly ellagitannins.

152 t (OPVS-E) included gallic acid derivatives, hydrolysable tannins, flavonoids, fatty acids, and anaca

153 a key intermediate in the synthesis of plant hydrolysable tannins, is also a primary anti-inflammator

154 BAK is abundant in phenolic acids, OAKs in hydrolysable tannins.

155 -d-glucose, a precursor for the synthesis of hydrolysable tannins.

156 Flavon-3-ols and hydrolysable-tannins were also found.

157 e ester bond in (T)PUs might be sufficiently hydrolysable to enable at least partial biodegradation o